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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2915
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ins1
Name: insulin 1
Acc ID: CHEBI:17254
Term: 4-methylcatechol
Definition: A methylcatechol having a single methyl substituent at the 4-position. It has been isolated from Picea abies.
Chemical ID: MESH:C018599
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ins1decreases expressionEXP 6480464CTD4-methylcatechol results in decreased expression of INS1 mRNAPMID:29473434
Ins1multiple interactionsEXP 6480464CTD[4-methylcatechol co-treated with Glucose] results in increased secretion of INS1 proteinPMID:29473434
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