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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1589867
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Spen
Name: spen family transcriptional repressor
Acc ID: CHEBI:16842
Term: formaldehyde
Definition: An aldehyde resulting from the formal oxidation of methanol.
Chemical ID: MESH:D005557
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Spendecreases expressionISORGD:13509796480464CTDFormaldehyde results in decreased expression of SPEN mRNA

PMID:17938736, PMID:20655997
Spenincreases expressionISORGD:13509796480464CTDFormaldehyde results in increased expression of SPEN mRNA

PMID:27905399
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.