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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61928
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hif1a
Name: hypoxia inducible factor 1 subunit alpha
Acc ID: CHEBI:136604
Term: cyclohexyl isocyanate
Definition: An isocyanate comprising a cyclohexane core with a single isocyanato substituent.
Chemical ID: MESH:C000536
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hif1amultiple interactionsEXP 6480464CTD[cobaltous chloride results in increased activity of HIF1A protein] which results in decreased susceptibility to cyclohexylisocyanatePMID:14980978
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