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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1350913
Species: Homo sapiens
RGD Object: Gene
Symbol: BNIP3
Name: BCL2 interacting protein 3
Acc ID: CHEBI:132774
Term: roxadustat
Definition: An N-acylglycine resulting from the formal condensation of the amino group of glycine with the carboxy group of 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid. It is an inhibitor of hypoxia inducible factor prolyl hydroxylase (HIF-PH).
Chemical ID: MESH:C584543
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BNIP3multiple interactionsISOBnip3 (Rattus norvegicus)6480464CTDroxadustat promotes the reaction [Hyaluronic Acid results in increased expression of BNIP3 protein]PMID:27082295
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