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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2482
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp7a1
Name: cytochrome P450 family 7 subfamily A member 1
Acc ID: CHEBI:1296
Term: 20-hydroxycholesterol
Definition: An oxysterol that is cholesterol substituted by a hydroxy group at position 20.
Chemical ID: MESH:C025813
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp7a1increases metabolic processingEXP 6480464CTDCYP7A1 protein results in increased metabolism of 20-hydroxycholesterolPMID:10882719
Cyp7a1increases metabolic processingISOCYP7A1 (Homo sapiens)6480464CTDCYP7A1 protein results in increased metabolism of 20-hydroxycholesterolPMID:10882719
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