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RGD ID: 732801
Species: Homo sapiens
RGD Object: Gene
Symbol: IDE
Name: insulin degrading enzyme
Acc ID: DOID:9352
Term: type 2 diabetes mellitus
Definition: A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. (DO)
Definition Source(s): "DO" "DO", "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IDE IAGP 1626697RGDDNA:haplotype::CC haplotype of SNPs rs2209972 and rs1887922 in men of European descent from the Framingham Heart Study 
IDEno_associationIAGP 1626698RGDDNA:SNP,haplotype::no association with 21 single-marker SNPs or with 13 multi-marker haplotypes in 4206 individuals from Scandinavia and Canada 
IDE ISOIde (Rattus norvegicus)737717RGDDNA:missense mutations, haplotype:exon:p.H18R, p.A890V (rat) 
IDE ISOIde (Mus musculus)737718RGD  
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