GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cxcl6 | increases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of CXCL5 mRNA; Tetrachlorodibenzodioxin results in increased expression of CXCL6 mRNA | PMID:15644576 PMID:19692669 | Cxcl6 | increases expression | ISO | Cxcl5 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of CXCL5 mRNA | PMID:16054899 PMID:26862745 PMID:28973351 PMID:32553695 | Cxcl6 | multiple interactions | ISO | Cxcl5 (Mus musculus) | 6480464 | CTD | [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL5 mRNA]; [Tetrachlorodibenzodioxin co-treated with EGF protein] results in increased expression of CXCL5 mRNA; AHRR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL5 mRNA]; IL1B protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL5 mRNA]; N-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL5 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of CXCL5 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [EGF protein results in increased expression of CXCL5 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [[AHR protein binds to ARNT protein] which binds to CXCL5 promoter] | PMID:15667827 PMID:16054899 PMID:26862745 PMID:28973351 | | ||||||||||||||||||||||
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