Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3055
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mbl1
Name: mannose binding lectin 1
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mbl1multiple interactionsISOMbl1 (Mus musculus)6480464CTD[MBL1 co-treated with MBL2] promotes the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of CCL22 mRNA]; [MBL1 co-treated with MBL2] promotes the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of CXCL2 mRNA]; [MBL1 co-treated with MBL2] promotes the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of IL21 mRNA]; [MBL1 co-treated with MBL2] promotes the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of IL22RA2 mRNA]; [MBL1 co-treated with MBL2] promotes the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of IRF4 mRNA]; [MBL1 co-treated with MBL2] promotes the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of KIR3DL2 mRNA]; [MBL1 co-treated with MBL2] promotes the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of MT2 mRNA]; [MBL1 co-treated with MBL2] promotes the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of NLRP10 mRNA]; [MBL1 co-treated with MBL2] promotes the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of NLRP4B mRNA]; [MBL1 co-treated with MBL2] promotes the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of NLRP6 mRNA]; [MBL1 co-treated with MBL2] promotes the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of NTN1 mRNA]; [MBL1 co-treated with MBL2] promotes the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of RFTN1 mRNA]PMID:27106289
Go Back to source page   Continue to Ontology report