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GENE - TERM ANNOTATION REPORT

RGD ID: 18904537
Species: Heterocephalus glaber
RGD Object: Gene
Symbol: Afp
Name: alpha fetoprotein
Acc ID: DOID:684
Term: hepatocellular carcinoma
Definition: A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver. (DO)
Definition Source(s): http://cancergenome.nih.gov/cancersselected/LiverHepatocellularCarcinoma "DO" "DO", http://en.wikipedia.org/wiki/Hepatocellular_carcinoma "DO" "DO", http://www.omim.org/entry/114550 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Afp ISOAFP (Homo sapiens)9068941RGDprotein:increased expression:serum (human)PMID:22392353 REF_RGD_ID:125097525
Afpdisease_progressionISOAFP (Homo sapiens)9068941RGD PMID:28611981 REF_RGD_ID:126790579
Afpdisease_progressionISOAFP (Homo sapiens)9068941RGDassociated with hepatitis BPMID:25968302 REF_RGD_ID:126790583
AfpseverityISOAFP (Homo sapiens)9068941RGDprotein:increased expression:serum (human)PMID:22147961 REF_RGD_ID:14401581
AfptreatmentISOAfp (Rattus norvegicus)9068941RGD PMID:25999787 REF_RGD_ID:152177911
Afp ISOAFP (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanismPMID:15276417 PMID:24012840 PMID:28284560 PMID:32961231 PMID:9029167
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