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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1566127
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prss53
Name: serine protease 53
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prss53affects expressionEXP 6480464CTDbisphenol A affects the expression of PRSS53 mRNAPMID:25181051
Prss53decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of PRSS53 mRNAPMID:30816183 PMID:32528016 PMID:35192832
Prss53increases expressionEXP 6480464CTDbisphenol A results in increased expression of PRSS53 mRNAPMID:34947998
Prss53multiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of PRSS53 mRNAPMID:36041667
Prss53decreases expressionISOPrss53 (Mus musculus)6480464CTDbisphenol A results in decreased expression of PRSS53 mRNAPMID:32156529
Prss53decreases expressionISOPRSS53 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of PRSS53 mRNAPMID:27685785
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