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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550022
Species: Mus musculus
RGD Object: Gene
Symbol: Gnaq
Name: guanine nucleotide binding protein, alpha q polypeptide
Acc ID: CHEBI:50743
Term: cyproterone acetate
Definition: A steroid ester resulting from the formal condensation of the carboxy group of acetic acid with the 17-hydroxy group of cyproterone. It is an antiandrogenic drug which has recently been recognized to promote the occurrence and growth of intracranial meningiomas.
Chemical ID: MESH:D017373
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gnaqmultiple interactionsISOGNAQ (Homo sapiens)6480464CTD[Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to GNAQ protein modified form]PMID:28751236
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