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GENE - TERM ANNOTATION REPORT

RGD ID: 13853807
Species: Sus scrofa
RGD Object: Gene
Symbol: EXOC6
Name: exocyst complex component 6
Acc ID: GO:0006887
Term: exocytosis
Definition: A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for example of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.
Definition Source(s): GOC:mah, ISBN:0716731363, PMID:22323285
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EXOC6involved_inIBAPANTHER:PTN000294823 or SGD:S000003202 or dictyBase:DDB_G0293936150520179GO_Central GO_REF:0000033
EXOC6involved_inIEAUniProtKB-KW:KW-0268150520179UniProt GO_REF:0000043
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