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GENE - TERM ANNOTATION REPORT

8 Annotations Found.

An association has been curated linking Lepr and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from Nannipieri M, etal., Diabetes Care. 2006 Nov;29(11):2509-11.
  • The annotation has been inferred from sequence orthology with LEPR (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Nannipieri M, etal., Diabetes Care. 2006 Nov;29(11):2509-11.
  • 808 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 100 papers in RGD have been used to annotate Lepr
  • Qualifier: susceptibility
  • Curation Notes: DNA:insertion:3' utr (human)


  • An association has been curated linking Lepr and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from Qu Y, etal., Diabetes Res Clin Pract. 2008 Jul;81(1):33-7. Epub 2008 Apr 24.
  • The annotation has been inferred from sequence orthology with LEPR (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Qu Y, etal., Diabetes Res Clin Pract. 2008 Jul;81(1):33-7. Epub 2008 Apr 24.
  • 808 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 100 papers in RGD have been used to annotate Lepr
  • Curation Notes: DNA:polymorphisms (human)


  • An association has been curated linking Lepr and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from de Luca C, etal., J Clin Invest. 2005 Dec;115(12):3484-93. Epub 2005 Nov 10.
  • The annotation has been inferred from sequence orthology with Lepr (Mus musculus) [(IMP) inferred from mutant phenotype]
  • 8 additional annotations were made from de Luca C, etal., J Clin Invest. 2005 Dec;115(12):3484-93. Epub 2005 Nov 10.
  • 808 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 100 papers in RGD have been used to annotate Lepr
  • Qualifier: treatment


  • An association has been curated linking Lepr and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred by association of genotype and phenotype (IAGP)
  •  
  • The annotation was made from Hattori T, etal., Nutr Diabetes. 2011 Jan 31;1:e1. doi: 10.1038/nutd.2010.1.
  • 30 additional annotations were made from Hattori T, etal., Nutr Diabetes. 2011 Jan 31;1:e1. doi: 10.1038/nutd.2010.1.
  • 808 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 100 papers in RGD have been used to annotate Lepr


  • An association has been curated linking Lepr and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with LEPR (Homo sapiens) [(EXP) inferred from experiment]
  • 808 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 100 papers in RGD have been used to annotate Lepr
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:20175764 PMID:22933112 PMID:24263156 PMID:26939912


  • An association has been curated linking Lepr and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from Swellam M and Hamdy N, IUBMB Life. 2012 Feb;64(2):180-6. doi: 10.1002/iub.597. Epub 2012 Jan 3.
  • The annotation has been inferred from sequence orthology with LEPR (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 11 additional annotations were made from Swellam M and Hamdy N, IUBMB Life. 2012 Feb;64(2):180-6. doi: 10.1002/iub.597. Epub 2012 Jan 3.
  • 808 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 100 papers in RGD have been used to annotate Lepr
  • Curation Notes: associated with nonalcoholic fatty liver disease;DNA:intron:c.2673+1118C>T (rs6700896) (human)


  • An association has been curated linking Lepr and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence or structural similarity (ISS)
  •  
  • The annotation was made from RGD automated import pipeline for MGI gene-to-disease annotations
  • The annotation has been inferred from sequence or structural similarity with Lepr (Mus musculus) [(IAGP) inferred by association of genotype and phenotype]
  • 808 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 100 papers in RGD have been used to annotate Lepr
  • Curation Notes: OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036


  • An association has been curated linking Lepr and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred by association of genotype and phenotype (IAGP)
  •  
  • The annotation was made from Schauer A, etal., ESC Heart Fail. 2020 Oct;7(5):2123-2134. doi: 10.1002/ehf2.12915. Epub 2020 Jul 25.
  • 39 additional annotations were made from Schauer A, etal., ESC Heart Fail. 2020 Oct;7(5):2123-2134. doi: 10.1002/ehf2.12915. Epub 2020 Jul 25.
  • 808 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 100 papers in RGD have been used to annotate Lepr
  • Curation Notes: DNA:mutations:cds: : (rat)


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