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GENE - TERM ANNOTATION REPORT

7 Annotations Found.

An association has been curated linking NFE2L2 and Chemical and Drug Induced Liver Injury in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Osburn WO, etal., Toxicol Sci. 2008 Jul;104(1):218-27. Epub 2008 Apr 15.
  • The annotation has been inferred from sequence orthology with Nfe2l2 (Mus musculus) [(IMP) inferred from mutant phenotype]
  • 5 additional annotations were made from Osburn WO, etal., Toxicol Sci. 2008 Jul;104(1):218-27. Epub 2008 Apr 15.
  • 531 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 80 papers in RGD have been used to annotate NFE2L2


    • An association has been curated linking NFE2L2 and Chemical and Drug Induced Liver Injury in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Yu W, etal., Life Sci. 2020 Feb 15;243:117274. doi: 10.1016/j.lfs.2020.117274. Epub 2020 Jan 9.
  • The annotation has been inferred from sequence orthology with Nfe2l2 (Mus musculus) [(IEP) inferred from expression pattern]
  • 2 additional annotations were made from Yu W, etal., Life Sci. 2020 Feb 15;243:117274. doi: 10.1016/j.lfs.2020.117274. Epub 2020 Jan 9.
  • 531 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 80 papers in RGD have been used to annotate NFE2L2
  • Qualifier: treatment


    • An association has been curated linking NFE2L2 and Chemical and Drug Induced Liver Injury in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Mahmoud AM, etal., Environ Sci Pollut Res Int. 2020 Mar;27(8):7910-7921. doi: 10.1007/s11356-019-07532-6. Epub 2019 Dec 31.
  • The annotation has been inferred from sequence orthology with Nfe2l2 (Rattus norvegicus) [(IEP) inferred from expression pattern]
  • 12 additional annotations were made from Mahmoud AM, etal., Environ Sci Pollut Res Int. 2020 Mar;27(8):7910-7921. doi: 10.1007/s11356-019-07532-6. Epub 2019 Dec 31.
  • 531 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 80 papers in RGD have been used to annotate NFE2L2
  • Qualifier: treatment
  • Curation Notes: induced by methotrexate (CHEBI:44185), treated by ferulic acid (CHEBI:17620)


    • An association has been curated linking NFE2L2 and Chemical and Drug Induced Liver Injury in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Zheng L, etal., Biomed Pharmacother. 2018 Jan;97:481-488. doi: 10.1016/j.biopha.2017.10.153. Epub 2017 Nov 6.
  • The annotation has been inferred from sequence orthology with Nfe2l2 (Rattus norvegicus) [(IEP) inferred from expression pattern] & Nfe2l2 (Mus musculus) [(IEP) inferred from expression pattern]
  • 149 additional annotations were made from Zheng L, etal., Biomed Pharmacother. 2018 Jan;97:481-488. doi: 10.1016/j.biopha.2017.10.153. Epub 2017 Nov 6.
  • 531 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 80 papers in RGD have been used to annotate NFE2L2
  • Qualifier: treatment


    • An association has been curated linking NFE2L2 and Chemical and Drug Induced Liver Injury in Homo sapiens.        

  • The association was inferred from experiment (EXP)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • 531 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 80 papers in RGD have been used to annotate NFE2L2
  • Curation Notes: CTD Direct Evidence: therapeutic
  • Original References(s): PMID:22491424 PMID:22627062 PMID:24813929 PMID:26958860 PMID:30215777


    • An association has been curated linking NFE2L2 and Chemical and Drug Induced Liver Injury in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Abo El-Magd NF and Eraky SM, Life Sci. 2020 Mar 1;244:117331. doi: 10.1016/j.lfs.2020.117331. Epub 2020 Jan 20.
  • The annotation has been inferred from sequence orthology with Nfe2l2 (Rattus norvegicus) [(IEP) inferred from expression pattern]
  • 2 additional annotations were made from Abo El-Magd NF and Eraky SM, Life Sci. 2020 Mar 1;244:117331. doi: 10.1016/j.lfs.2020.117331. Epub 2020 Jan 20.
  • 531 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 80 papers in RGD have been used to annotate NFE2L2
  • Qualifier: treatment


    • An association has been curated linking NFE2L2 and Chemical and Drug Induced Liver Injury in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Abdelzaher WY, etal., Immunopharmacol Immunotoxicol. 2020 Feb 18:1-9. doi: 10.1080/08923973.2020.1727499.
  • The annotation has been inferred from sequence orthology with Nfe2l2 (Rattus norvegicus) [(IEP) inferred from expression pattern]
  • 2 additional annotations were made from Abdelzaher WY, etal., Immunopharmacol Immunotoxicol. 2020 Feb 18:1-9. doi: 10.1080/08923973.2020.1727499.
  • 531 RGD objects have been annotated to Chemical and Drug Induced Liver Injury  (DOID:9007383)
  • 80 papers in RGD have been used to annotate NFE2L2
  • Qualifier: treatment


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