Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - TERM ANNOTATION REPORT

10 Annotations Found.

An association has been curated linking F8 and factor VIII deficiency in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Guillet B, etal., Hum Mutat. 2006 Jul;27(7):676-85.
  • The annotation has been inferred from sequence orthology with F8 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Guillet B, etal., Hum Mutat. 2006 Jul;27(7):676-85.
  • 30 RGD objects have been annotated to factor VIII deficiency  (DOID:12134)
  • 28 papers in RGD have been used to annotate F8


    • An association has been curated linking F8 and factor VIII deficiency in Rattus norvegicus.        

  • The association was inferred from mutant phenotype (IMP)
    		•  
  • The annotation was made from Nielsen LN, etal., J Thromb Haemost. 2014 Aug;12(8):1274-82. doi: 10.1111/jth.12635.
  • 25 additional annotations were made from Nielsen LN, etal., J Thromb Haemost. 2014 Aug;12(8):1274-82. doi: 10.1111/jth.12635.
  • 30 RGD objects have been annotated to factor VIII deficiency  (DOID:12134)
  • 28 papers in RGD have been used to annotate F8


    • An association has been curated linking F8 and factor VIII deficiency in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from VandenDriessche T, etal., Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):10379-84.
  • The annotation has been inferred from sequence orthology with F8 (Homo sapiens) [(IMP) inferred from mutant phenotype]
  • 2 additional annotations were made from VandenDriessche T, etal., Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):10379-84.
  • 30 RGD objects have been annotated to factor VIII deficiency  (DOID:12134)
  • 28 papers in RGD have been used to annotate F8
  • Qualifier: treatment


    • An association has been curated linking F8 and factor VIII deficiency in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Akkarapatumwong V, etal., Hum Mutat. 2000 Jan;15(1):117-8.
  • The annotation has been inferred from sequence orthology with F8 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Akkarapatumwong V, etal., Hum Mutat. 2000 Jan;15(1):117-8.
  • 30 RGD objects have been annotated to factor VIII deficiency  (DOID:12134)
  • 28 papers in RGD have been used to annotate F8
  • Curation Notes: DNA:missense mutations, nonsense mutations, frameshift mutation:exon:multiple


    • An association has been curated linking F8 and factor VIII deficiency in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from OMIM Disease Annotation Pipeline
  • The annotation has been inferred from sequence orthology with F8 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 30 RGD objects have been annotated to factor VIII deficiency  (DOID:12134)
  • 28 papers in RGD have been used to annotate F8


    • An association has been curated linking F8 and factor VIII deficiency in Rattus norvegicus.        

  • The association was inferred by association of genotype and phenotype (IAGP)
    		•  
  • The annotation was made from Booth CJ, etal., J Thromb Haemost. 2010 Nov;8(11):2472-7. doi: 10.1111/j.1538-7836.2010.03978.x.
  • 12 additional annotations were made from Booth CJ, etal., J Thromb Haemost. 2010 Nov;8(11):2472-7. doi: 10.1111/j.1538-7836.2010.03978.x.
  • 30 RGD objects have been annotated to factor VIII deficiency  (DOID:12134)
  • 28 papers in RGD have been used to annotate F8
  • Curation Notes: DNA,protein:missense mutation,decreased activity:exon:p.L176P(rat)


    • An association has been curated linking F8 and factor VIII deficiency in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with F8 (Homo sapiens) [(EXP) inferred from experiment]
  • 30 RGD objects have been annotated to factor VIII deficiency  (DOID:12134)
  • 28 papers in RGD have been used to annotate F8
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:11918545 PMID:16051741


    • An association has been curated linking F8 and factor VIII deficiency in Rattus norvegicus.        

  • The association was inferred from mutant phenotype (IMP)
    		•  
  • The annotation was made from Shi Q, etal., Blood Adv. 2020 Jan 14;4(1):55-65. doi: 10.1182/bloodadvances.2019000944.
  • 28 additional annotations were made from Shi Q, etal., Blood Adv. 2020 Jan 14;4(1):55-65. doi: 10.1182/bloodadvances.2019000944.
  • 30 RGD objects have been annotated to factor VIII deficiency  (DOID:12134)
  • 28 papers in RGD have been used to annotate F8
  • Qualifier: treatment


    • An association has been curated linking F8 and factor VIII deficiency in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with F8 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 30 RGD objects have been annotated to factor VIII deficiency  (DOID:12134)
  • 28 papers in RGD have been used to annotate F8
  • Curation Notes: ClinVar Annotator: match by term: Factor 8 deficiency, congenital | ClinVar Annotator: match by term: Factor VIII deficiency, congenital | ClinVar Annotator: match by term: Hemophilia A | ClinVar Annotator: match by term: Hemophilia A, congenital
  • Original References(s): PMID:10215414 PMID:10338101 PMID:10404764 PMID:10519986 PMID:10609755 PMID:10896236 PMID:10910910 PMID:10910913 PMID:11102988 PMID:11110718 PMID:11179760 PMID:11189482 PMID:11251334 PMID:11298607 PMID:11341489 PMID:11410838 PMID:11442643 PMID:11554935 PMID:11713379 PMID:11748850 PMID:11843836 PMID:11857744 PMID:11858487 PMID:12139751 PMID:12204009 PMID:12325022 PMID:12351418 PMID:12406074 PMID:12871415 PMID:12884004 PMID:1301194 PMID:1301932 PMID:1301960 PMID:1349567 PMID:1357455 PMID:1412186 PMID:1523102 PMID:15471879 PMID:15569173 PMID:1559571 PMID:15625837 PMID:15670040 PMID:1569180 PMID:1569181 PMID:15710596 PMID:15735794 PMID:15741993 PMID:15810915 PMID:15921397 PMID:15996930 PMID:16128892 PMID:16173970 PMID:1639429 PMID:1643024 PMID:16601827 PMID:1671991 PMID:16769589 PMID:16786531 PMID:16834740 PMID:16972227 PMID:17209060 PMID:17222201 PMID:17445092 PMID:17498081 PMID:17550859 PMID:17610549 PMID:17610560 PMID:18034822 PMID:18184865 PMID:18217193 PMID:18371163 PMID:18387975 PMID:18403393 PMID:1840568 PMID:18479430 PMID:1851341 PMID:18565236 PMID:18600086 PMID:18691168 PMID:1908096 PMID:1908817 PMID:1923751 PMID:1924291 PMID:19369668 PMID:19377476 PMID:19448530 PMID:19456877 PMID:19473408 PMID:19473423 PMID:19548904 PMID:1969840 PMID:19719548 PMID:19719828 PMID:1973901 PMID:19740093 PMID:1979502 PMID:20028422 PMID:20102490 PMID:20108389 PMID:20193250 PMID:20300295 PMID:20301578 PMID:20331753 PMID:20331761 PMID:20431853 PMID:20533009 PMID:20536985 PMID:20800587 PMID:20860608 PMID:2104741 PMID:2104766 PMID:2105106 PMID:2105906 PMID:2106480 PMID:21070499 PMID:2107542 PMID:2109644 PMID:2110545 PMID:2121026 PMID:2121641 PMID:21217077 PMID:2125022 PMID:21371196 PMID:21462120 PMID:2159433 PMID:21645180 PMID:21645224 PMID:21645226 PMID:21689372 PMID:21751985 PMID:21838755 PMID:21883705 PMID:21910785 PMID:22103590 PMID:22958177 PMID:23534532 PMID:23625609 PMID:23711237 PMID:23711294 PMID:23809411 PMID:23812942 PMID:23913812 PMID:23926300 PMID:23961341 PMID:23963097 PMID:24033266 PMID:24086941 PMID:24108539 PMID:24118398 PMID:24134483 PMID:2473810 PMID:24845853 PMID:2493803 PMID:2495245 PMID:24953131 PMID:2498882 PMID:2506948 PMID:2510835 PMID:25326637 PMID:25628142 PMID:2563431 PMID:2567219 PMID:25708597 PMID:25741868 PMID:25741908 PMID:25824987 PMID:25854144 PMID:25948085 PMID:25955082 PMID:26308136 PMID:26383047 PMID:26879396 PMID:26897466 PMID:27292088 PMID:27868395 PMID:27943580 PMID:28252515 PMID:2831458 PMID:2833855 PMID:2835307 PMID:28492532 PMID:2861360 PMID:2887317 PMID:2901224 PMID:2907841 PMID:29296726 PMID:2986011 PMID:2987704 PMID:2993888 PMID:3035554 PMID:30534853 PMID:30913330 PMID:3097553 PMID:31064749 PMID:3122181 PMID:3131627 PMID:3137981 PMID:32166871 PMID:32581362 PMID:34355501 PMID:35014236 PMID:6253938 PMID:6438527 PMID:7579394 PMID:7662970 PMID:7728145 PMID:7794769 PMID:7959679 PMID:7984443 PMID:8011517 PMID:8052958 PMID:8054459 PMID:8069313 PMID:8281136 PMID:8307558 PMID:8322269 PMID:8449505 PMID:8485051 PMID:8490618 PMID:8497853 PMID:8547094 PMID:8576960 PMID:8584995 PMID:8639447 PMID:8644728 PMID:9184393 PMID:9326186 PMID:9452104 PMID:9569189 PMID:9594277 PMID:9792405 PMID:9829908 PMID:9886318


    • An association has been curated linking F8 and factor VIII deficiency in Rattus norvegicus.        

  • The association was inferred from sequence or structural similarity (ISS)
    		•  
  • The annotation was made from RGD automated import pipeline for MGI gene-to-disease annotations
  • The annotation has been inferred from sequence or structural similarity with F8 (Mus musculus) [(IAGP) inferred by association of genotype and phenotype]
  • 30 RGD objects have been annotated to factor VIII deficiency  (DOID:12134)
  • 28 papers in RGD have been used to annotate F8
  • Curation Notes: OMIM:306700


    • Go Back to source page   Continue to Ontology report