Phenominer Database Results (76 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Duration Post Insult Time Value Experiment Notes Record ID Study ID
FHH-Chr 1BN/Mcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait male 49 days-63 days 10 4.73 % 2.0 6.34 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 49411 461
FHH-Chr 1BN/Mcwi time to peak heart contraction air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 10 1125.69 s 42.89 135.62 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50242 461
FHH-Chr 1BN/Mcwi heart contraction pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49 days-63 days 10 43.4 mmHg 3.35 10.61 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50012 461
FHH-Chr 1BN/Mcwi left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 9 125.16 mmHg 4.18 12.54 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45519 461
FHH-Chr 1BN/Mcwi left ventricular diastolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 9 54.65 mmHg 3.65 10.95 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46432 461
FHH-Chr 1BN/Mcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 9 271.35 beats/min 9.78 29.34 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48223 461
FHH-Chr 1BN/Mcwi percent change in heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 9 post-ischemic value/pre-ischemic value x 100% 81.32 % 3.3 9.9 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48432 461
FHH-Chr 1BN/Mcwi left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 10 5.34 mmHg 0.16 0.51 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49192 461
FHH-Chr 1BN/Mcwi arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 9 7.15 ml/min/g 0.93 2.79 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46227 461
FHH-Chr 1BN/Mcwi arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 10 15.29 ml/min/g 0.72 2.27 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46679 461
FHH-Chr 1BN/Mcwi left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 9 68.47 mmHg 3.87 11.62 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47937 461
FHH-Chr 1BN/Mcwi heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 10 241.58 beats/min 8.76 27.71 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47608 461
FHH-Chr 1BN/Mcwi left ventricular diastolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 10 50.14 mmHg 2.18 6.89 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46443 461
FHH-Chr 1BN/Mcwi percent change in left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 10 post-ischemic value/pre-ischemic value x 100% 59.13 % 8.47 26.78 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48771 461
FHH-Chr 1BN/Mcwi left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 9 5.29 mmHg 0.19 0.57 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49203 461
FHH-Chr 1BN/Mcwi heart left ventricle infarction weight to total heart left ventricle weight ratio air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait male 49 days-63 days 10 10.78 % 4.5 14.23 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 49713 461
FHH-Chr 1BN/Mcwi heart left ventricle infarction weight to total heart left ventricle weight ratio air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait female 49 days-63 days 10 9.2 % 4.39 13.88 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 49724 461
FHH-Chr 1BN/Mcwi time to onset of heart contraction air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49 days-63 days 10 946.07 s 60.82 192.34 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49325 461
FHH-Chr 1BN/Mcwi time to onset of heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49 days-63 days 9 890.95 s 27.06 81.19 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50134 461
FHH-Chr 1BN/Mcwi left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 9 94.47 mmHg 5.26 15.79 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49903 461
FHH-Chr 1BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 10 0.39 IU/g 0.08 0.27 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47511 461
FHH-Chr 1BN/Mcwi left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 10 146.91 mmHg 5.97 18.87 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48650 461
FHH-Chr 1BN/Mcwi left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 9 119.87 mmHg 4.19 12.56 balloon tipped catheter with pressure transducer in isolated perfused heart 0 46765 461
FHH-Chr 1BN/Mcwi percent change in arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 9 post-ischemic value/pre-ischemic value x 100% 54.91 % 3.73 11.2 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46092 461
FHH-Chr 1BN/Mcwi left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 9 109.03 mmHg 3.72 11.16 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 44841 461
FHH-Chr 1BN/Mcwi left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 9 39.82 mmHg 8.0 23.99 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45285 461
FHH-Chr 1BN/Mcwi percent change in left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 8 post-ischemic value/pre-ischemic value x 100% 64.16 % 1.79 5.07 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46345 461
FHH-Chr 1BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 0.21 IU/g 0.04 0.11 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47350 461
FHH-Chr 1BN/Mcwi arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 10 7.05 ml/min/g 0.94 2.97 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46216 461
FHH-Chr 1BN/Mcwi left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 9 40.17 mmHg 2.58 7.75 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47716 461
FHH-Chr 1BN/Mcwi heart contraction pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49 days-63 days 10 43.3 mmHg 2.9 9.17 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50023 461
FHH-Chr 1BN/Mcwi heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 10 278.29 beats/min 12.74 40.29 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47597 461
FHH-Chr 1BN/Mcwi percent change in left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 10 post-ischemic value/pre-ischemic value x 100% 68.29 % 3.41 10.79 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48782 461
FHH-Chr 1BN/Mcwi left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 10 148.32 mmHg 6.53 20.64 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45744 461
FHH-Chr 1BN/Mcwi left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 10 152.1 mmHg 6.15 19.44 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45755 461
FHH-Chr 1BN/Mcwi arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 10 14.88 ml/min/g 1.14 3.59 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46668 461
FHH-Chr 1BN/Mcwi arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 10 12.46 ml/min/g 0.9 2.85 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46885 461
FHH-Chr 1BN/Mcwi left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 9 99.51 mmHg 6.66 19.97 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 44830 461
FHH-Chr 1BN/Mcwi percent change in arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 10 post-ischemic value/pre-ischemic value x 100% 47.68 % 2.98 9.41 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47092 461
FHH-Chr 1BN/Mcwi percent change in arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 10 post-ischemic value/pre-ischemic value x 100% 55.37 % 3.7 11.71 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46081 461
FHH-Chr 1BN/Mcwi left ventricular diastolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 10 5.18 mmHg 0.24 0.77 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47223 461
FHH-Chr 1BN/Mcwi percent change in heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 10 post-ischemic value/pre-ischemic value x 100% 98.7 % 10.16 32.14 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48421 461
FHH-Chr 1BN/Mcwi left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 10 53.5 mmHg 6.47 20.46 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45296 461
FHH-Chr 1BN/Mcwi arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 10 7.06 ml/min/g 0.69 2.19 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 44733 461
FHH-Chr 1BN/Mcwi arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 10 7.43 ml/min/g 0.25 0.79 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 44744 461
FHH-Chr 1BN/Mcwi arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 9 12.92 ml/min/g 1.26 3.79 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46896 461
FHH-Chr 1BN/Mcwi heart contraction pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49 days-63 days 10 41.1 mmHg 1.92 6.08 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48048 461
FHH-Chr 1BN/Mcwi time to onset of heart contraction air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49 days-63 days 10 900.59 s 38.21 120.84 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49314 461
FHH-Chr 1BN/Mcwi time to onset of heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49 days-63 days 8 924.55 s 40.3 113.98 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50145 461
FHH-Chr 1BN/Mcwi time to peak heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 10 1152.5 s 25.98 82.15 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46563 461
FHH-Chr 1BN/Mcwi percent change in left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 10 post-ischemic value/pre-ischemic value x 100% 35.97 % 3.49 11.03 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48553 461
FHH-Chr 1BN/Mcwi left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 10 143.14 mmHg 6.57 20.76 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48639 461
FHH-Chr 1BN/Mcwi left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 9 59.33 mmHg 8.69 26.07 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47926 461
FHH-Chr 1BN/Mcwi percent change in left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 9 post-ischemic value/pre-ischemic value x 100% 45.23 % 9.67 29.0 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46334 461
FHH-Chr 1BN/Mcwi heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 10 260.6 beats/min 21.86 69.14 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45163 461
FHH-Chr 1BN/Mcwi heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 10 223.08 beats/min 5.09 16.11 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45174 461
FHH-Chr 1BN/Mcwi percent change in arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 10 post-ischemic value/pre-ischemic value x 100% 49.61 % 2.83 8.95 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47103 461
FHH-Chr 1BN/Mcwi percent change in heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 10 post-ischemic value/pre-ischemic value x 100% 93.4 % 3.73 11.8 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48321 461
FHH-Chr 1BN/Mcwi heart contraction pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49 days-63 days 9 42.22 mmHg 2.99 8.96 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48059 461
FHH-Chr 1BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 0.34 IU/g 0.06 0.19 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47486 461
FHH-Chr 1BN/Mcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 10 251.12 beats/min 19.54 61.78 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48960 461
FHH-Chr 1BN/Mcwi left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 10 103.64 mmHg 6.21 19.65 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49914 461
FHH-Chr 1BN/Mcwi time to peak heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 9 1143.03 s 39.64 118.91 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46574 461
FHH-Chr 1BN/Mcwi left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 8 116.03 mmHg 4.99 14.12 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45530 461
FHH-Chr 1BN/Mcwi percent change in left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 10 post-ischemic value/pre-ischemic value x 100% 26.78 % 6.6 20.88 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48542 461
FHH-Chr 1BN/Mcwi left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 8 110.75 mmHg 4.97 14.05 balloon tipped catheter with pressure transducer in isolated perfused heart 0 46776 461
FHH-Chr 1BN/Mcwi left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 9 40.56 mmHg 4.9 14.71 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47727 461
FHH-Chr 1BN/Mcwi left ventricular diastolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 10 5.18 mmHg 0.28 0.89 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47212 461
FHH-Chr 1BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 0.33 IU/g 0.1 0.3 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47373 461
FHH-Chr 1BN/Mcwi percent change in left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 8 post-ischemic value/pre-ischemic value x 100% 97.25 % 4.99 14.12 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 44944 461
FHH-Chr 1BN/Mcwi percent change in heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 10 post-ischemic value/pre-ischemic value x 100% 95.53 % 9.46 29.91 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48310 461
FHH-Chr 1BN/Mcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 9 221.52 beats/min 13.46 40.36 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48971 461
FHH-Chr 1BN/Mcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 10 258.51 beats/min 7.81 24.69 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48212 461
FHH-Chr 1BN/Mcwi percent change in left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 9 post-ischemic value/pre-ischemic value x 100% 71.44 % 10.82 32.47 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 44933 461
FHH-Chr 1BN/Mcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait female 49 days-63 days 9 4.81 % 2.75 8.25 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 49422 461
FHH-Chr 1BN/Mcwi time to peak heart contraction air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 10 1154.0 s 24.51 77.5 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50253 461