SS-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
3 |
1.67 |
ng/ml/h |
0.55 |
0.96 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51006 |
481 |
SS-Chr 18BN/Mcwi |
urine sodium excretion rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
urine sodium amount |
male |
87 days-120 days |
6 |
1.16 |
mEq/d |
0.25 |
0.62 |
flame atomic emission spectrometry |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51044 |
481 |
SS-Chr 18BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
7 |
0.35 |
mg/dl |
0.01 |
0.02 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
51171 |
481 |
SS-Chr 18BN/Mcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
heart pumping trait |
male |
87 days-120 days |
7 |
3.43 |
beats/min |
11.16 |
29.52 |
vascular fluid filled catheter |
|
0 |
Moms and pups used in studies were fed Dyets |
51086 |
481 |
SS-Chr 18BN/Mcwi |
urine sodium excretion rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
urine sodium amount |
male |
87 days-120 days |
8 |
1.25 |
mEq/d |
0.15 |
0.43 |
flame atomic emission spectrometry |
|
0 |
Moms and pups used in studies were fed Dyets |
51264 |
481 |
SS-Chr 18BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
5 |
0.29 |
mg/dl |
0.01 |
0.02 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Teklad |
51313 |
481 |
SS-Chr 18BN/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87 days-120 days |
3 |
107.87 |
mmHg |
1.27 |
2.21 |
vascular fluid filled catheter |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51327 |
481 |
SS-Chr 18BN/Mcwi |
heart rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
heart pumping trait |
male |
87 days-120 days |
5 |
394.09 |
beats/min |
7.89 |
17.63 |
vascular fluid filled catheter |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51379 |
481 |
SS-Chr 18BN/Mcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87 days-120 days |
5 |
-3.43 |
mmHg |
1.25 |
2.78 |
vascular fluid filled catheter |
|
0 |
Moms and pups used in studies were fed Teklad |
50804 |
481 |
SS-Chr 18BN/Mcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
heart pumping trait |
female |
87 days-120 days |
3 |
15.12 |
beats/min |
28.47 |
49.3 |
vascular fluid filled catheter |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50908 |
481 |
SS-Chr 18BN/Mcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
heart pumping trait |
female |
87 days-120 days |
5 |
-6.56 |
beats/min |
8.43 |
18.85 |
vascular fluid filled catheter |
|
0 |
Moms and pups used in studies were fed Teklad |
50980 |
481 |
SS-Chr 18BN/Mcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87 days-120 days |
5 |
-18.8 |
mmHg |
3.71 |
8.29 |
vascular fluid filled catheter |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50761 |
481 |
SS-Chr 18BN/Mcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87 days-120 days |
3 |
-6.83 |
mmHg |
2.51 |
4.35 |
vascular fluid filled catheter |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50765 |
481 |
SS-Chr 18BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
male |
87 days-120 days |
5 |
0.28 |
mg/dl |
0.06 |
0.14 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51533 |
481 |
SS-Chr 18BN/Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
blood creatinine amount |
female |
87 days-120 days |
2 |
0.37 |
mg/dl |
0.07 |
0.09 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51537 |
481 |
SS-Chr 18BN/Mcwi |
creatinine clearance |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
glomerular filtration trait |
male |
87 days-120 days |
6 |
1.92 |
ml/min |
0.12 |
0.28 |
urine creatinine analysis |
|
0 |
Moms and pups used in studies were fed Dyets |
51540 |
481 |
SS-Chr 18BN/Mcwi |
urine sodium excretion rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
urine sodium amount |
female |
87 days-120 days |
7 |
0.91 |
mEq/d |
0.11 |
0.28 |
flame atomic emission spectrometry |
|
0 |
Moms and pups used in studies were fed Teklad |
51519 |
481 |
SS-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
female |
87 days-120 days |
2 |
1.29 |
ng/ml/h |
0.49 |
0.69 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50569 |
481 |
SS-Chr 18BN/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87 days-120 days |
7 |
119.18 |
mmHg |
4.9 |
12.98 |
vascular fluid filled catheter |
|
0 |
Moms and pups used in studies were fed Dyets |
51819 |
481 |
SS-Chr 18BN/Mcwi |
heart rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
heart pumping trait |
female |
87 days-120 days |
3 |
465.42 |
beats/min |
20.72 |
35.89 |
vascular fluid filled catheter |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51383 |
481 |
SS-Chr 18BN/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87 days-120 days |
5 |
105.29 |
mmHg |
2.43 |
5.43 |
vascular fluid filled catheter |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51323 |
481 |
SS-Chr 18BN/Mcwi |
heart rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
heart pumping trait |
female |
87 days-120 days |
5 |
409.57 |
beats/min |
5.76 |
12.88 |
vascular fluid filled catheter |
|
0 |
Moms and pups used in studies were fed Teklad |
50881 |
481 |
SS-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
7 |
2.5 |
ng/ml/h |
0.55 |
1.46 |
radioimmunoassay |
|
0 |
Moms and pups used in studies were fed Dyets |
50387 |
481 |
SS-Chr 18BN/Mcwi |
creatinine clearance |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
glomerular filtration trait |
male |
87 days-120 days |
4 |
1.66 |
ml/min |
0.1 |
0.2 |
urine creatinine analysis |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51447 |
481 |
SS-Chr 18BN/Mcwi |
plasma renin activity level |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
renin activity |
male |
87 days-120 days |
5 |
2.8 |
ng/ml/h |
0.87 |
1.94 |
radioimmunoassay |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50565 |
481 |
SS-Chr 18BN/Mcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87 days-120 days |
7 |
-21.19 |
mmHg |
2.27 |
6.01 |
vascular fluid filled catheter |
|
0 |
Moms and pups used in studies were fed Dyets |
50625 |
481 |
SS-Chr 18BN/Mcwi |
creatinine clearance |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
glomerular filtration trait |
female |
87 days-120 days |
2 |
0.73 |
ml/min |
0.02 |
0.02 |
urine creatinine analysis |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51451 |
481 |
SS-Chr 18BN/Mcwi |
creatinine clearance |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
glomerular filtration trait |
female |
87 days-120 days |
4 |
1.03 |
ml/min |
0.2 |
0.41 |
urine creatinine analysis |
|
0 |
Moms and pups used in studies were fed Teklad |
51055 |
481 |
SS-Chr 18BN/Mcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
heart pumping trait |
male |
87 days-120 days |
5 |
10.88 |
beats/min |
6.24 |
13.95 |
vascular fluid filled catheter |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50904 |
481 |
SS-Chr 18BN/Mcwi |
urine sodium excretion rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
urine sodium amount |
female |
87 days-120 days |
4 |
0.79 |
mEq/d |
0.09 |
0.17 |
flame atomic emission spectrometry |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51048 |
481 |
SS-Chr 18BN/Mcwi |
heart rate |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
heart pumping trait |
male |
87 days-120 days |
7 |
383.32 |
beats/min |
7.64 |
20.22 |
vascular fluid filled catheter |
|
0 |
Moms and pups used in studies were fed Dyets |
51243 |
481 |
SS-Chr 18BN/Mcwi |
mean arterial blood pressure |
controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87 days-120 days |
5 |
117.87 |
mmHg |
3.37 |
7.54 |
vascular fluid filled catheter |
|
0 |
Moms and pups used in studies were fed Teklad |
52000 |
481 |