SHR/Bbb |
percentage of study population developing cerebrovascular lesions during a period of time |
controlled sodium content diet (3.7 mg/g) (for 140 days) and controlled sodium content drinking water (1 %) (for 140 days) and controlled potassium content diet (6.3 mg/g) (for 140 days) |
Rubattu S, et al., Nat Genet 1996 Aug;13(4):429-34 |
cerebrovascular system integrity trait |
both |
182 days
| 30 |
|
20.0 |
% |
|
|
ex vivo light microscopy |
0.0 |
0 |
69118 |
1125 |
SHR/Bbb |
body weight |
controlled protein content diet (19.7 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) and controlled sodium content diet (3.7 mg/g) (for 84 days) |
Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. |
body mass |
not specified |
126 days
| 18 |
|
289.0 |
g |
1.89 |
8.0 |
body weighing method |
0.0 |
0 |
97908 |
1938 |
SHR/Bbb |
systolic blood pressure |
controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days) |
Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. |
arterial blood pressure trait |
not specified |
70 days
| 18 |
undefined |
180.0 |
mmHg |
0.94 |
4.0 |
tail cuff plethysmography |
0.0 |
0 |
97911 |
1938 |
SHR/Bbb |
systolic blood pressure |
controlled protein content diet (19.7 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) and controlled sodium content diet (3.7 mg/g) (for 56 days) |
Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. |
arterial blood pressure trait |
not specified |
98 days
| 18 |
undefined |
189.0 |
mmHg |
1.41 |
6.0 |
tail cuff plethysmography |
0.0 |
0 |
97912 |
1938 |
SHR/Bbb |
urine total protein excretion rate |
controlled protein content diet (19.7 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) and controlled sodium content diet (3.7 mg/g) (for 56 days) |
Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. |
total urine protein amount |
not specified |
98 days
| 18 |
|
68.0 |
mg/d |
3.3 |
14.0 |
urine analysis |
0.0 |
0 |
97929 |
1938 |
SHR/Bbb |
urine total protein excretion rate |
controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days) |
Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. |
total urine protein amount |
not specified |
70 days
| 18 |
|
33.0 |
mg/d |
1.3 |
5.5 |
urine analysis |
0.0 |
0 |
97928 |
1938 |
SHR/Bbb |
urine total protein excretion rate |
controlled protein content diet (19.7 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) and controlled sodium content diet (3.7 mg/g) (for 84 days) |
Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. |
total urine protein amount |
not specified |
126 days
| 18 |
|
85.0 |
mg/d |
3.77 |
16.0 |
urine analysis |
0.0 |
0 |
97930 |
1938 |
SHR/Bbb |
body weight |
controlled protein content diet (19.7 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) and controlled sodium content diet (3.7 mg/g) (for 56 days) |
Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. |
body mass |
not specified |
98 days
| 18 |
|
260.0 |
g |
3.77 |
16.0 |
body weighing method |
0.0 |
0 |
97907 |
1938 |
SHR/Bbb |
body weight |
controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days) |
Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. |
body mass |
not specified |
70 days
| 18 |
|
220.0 |
g |
3.06 |
13.0 |
body weighing method |
0.0 |
0 |
97906 |
1938 |
SHR/Bbb |
systolic blood pressure |
controlled protein content diet (19.7 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) and controlled sodium content diet (3.7 mg/g) (for 84 days) |
Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. |
arterial blood pressure trait |
not specified |
126 days
| 18 |
undefined |
188.0 |
mmHg |
0.94 |
4.0 |
tail cuff plethysmography |
0.0 |
0 |
97913 |
1938 |
SHR/Bbb |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
control condition (for 0 hours) |
Steireif C, etal., J Hypertens. 2013 Nov;31(11):2203-12; discussion 2212. doi: 10.1097/HJH.0b013e3283642384. |
vasodilation trait |
male |
84 days
| 10 |
|
68.1 |
% |
4.3 |
13.6 |
wire myography |
0.0 |
0 |
109368 |
3141 |