Phenominer Database Results (28 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Site Method Duration Post Insult Time Value Clinical Measurement Notes Experiment Notes Record ID Study ID
SS-Sh2b3em1Mcwi-/- urine total protein excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data total urine protein amount male 70 days-77 days 16 81.78 mg/d 5.64 22.56 automated urine analysis 0 - 43503 421
SS-Sh2b3em1Mcwi-/- heart rate controlled sodium content diet (4 %) (for 12 days) PhysGen Knockout data heart pumping trait male 70 days-77 days 10 371.9 beats/min 5.06 16.01 radiotelemetry carotid artery 0 - 43657 421
SS-Sh2b3em1Mcwi-/- urine albumin excretion rate controlled sodium chloride content diet (0.4 %) (for 42 days) then controlled sodium chloride content diet (4 %) (for 10 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. urine albumin amount not specified 73 days 6 9.4 mg/d 2.4 5.88 urine albumin analysis 0.0 0 n=6-8 106527 3031
SS-Sh2b3em1Mcwi-/- heart wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data heart mass male 70 days-77 days 13 1.09 g 0.01 0.05 post excision weight measurement 0 - 43643 421
SS-Sh2b3em1Mcwi-/- urine albumin excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine albumin amount male 70 days-77 days 16 31.9 mg/d 4.57 18.29 automated urine analysis 0 - 43583 421
SS-Sh2b3em1Mcwi-/- spleen weight controlled sodium chloride content diet (0.4 %) (for 42 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. spleen mass not specified 63 days 4 2.4 g 0.2 0.4 post excision weight measurement 0.0 0 n=4-7 106509 3031
SS-Sh2b3em1Mcwi-/- spleen regulatory T cell count to total T cell count ratio controlled sodium chloride content diet (0.4 %) (for 42 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. T cell quantity not specified 63 days 4 5.2 % 0.3 0.6 flow cytometry method 0.0 0 n=4-7 -tregs blood % 106517 3031
SS-Sh2b3em1Mcwi-/- mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 70 days) then controlled sodium chloride content diet (4 %) (for 21 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. arterial blood pressure trait not specified 91 days 6 15sec/min for 3 hrs/day 135.7 mmHg 1.1 2.69 vascular fluid filled catheter 0.0 0 n=6-8 106523 3031
SS-Sh2b3em1Mcwi-/- heart rate controlled sodium content diet (4 %) (for 11 days) PhysGen Knockout data heart pumping trait male 70 days-77 days 12 373.58 beats/min 7.33 25.41 radiotelemetry carotid artery 0 - 43673 421
SS-Sh2b3em1Mcwi-/- left kidney wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data kidney mass male 70 days-77 days 13 1.36 g 0.03 0.1 post excision weight measurement 0 - 43629 421
SS-Sh2b3em1Mcwi-/- mean arterial blood pressure controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data arterial blood pressure trait male 70 days-77 days 14 1/3 systolic pressure + 2/3 diastolic pressure 120.79 mmHg 2.3 8.62 radiotelemetry carotid artery 0 - 43456 421
SS-Sh2b3em1Mcwi-/- mean arterial blood pressure controlled sodium content diet (4 %) (for 13 days) PhysGen Knockout data arterial blood pressure trait male 70 days-77 days 13 1/3 systolic pressure + 2/3 diastolic pressure 119.31 mmHg 3.73 13.45 radiotelemetry carotid artery 0 - 43472 421
SS-Sh2b3em1Mcwi-/- body weight controlled sodium content diet (4 %) (for 10 days) PhysGen Knockout data body mass male 70 days-77 days 18 315.9 g 5.3 22.7 whole body digital scale 0 - 43487 421
SS-Sh2b3em1Mcwi-/- blood T lymphocyte count controlled sodium chloride content diet (0.4 %) (for 42 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. T cell quantity not specified 63 days 4 7.0 x 10E6 cells/ml 0.4 0.8 flow cytometry method 0.0 0 n=4-7 106513 3031
SS-Sh2b3em1Mcwi-/- heart rate controlled sodium content diet (4 %) (for 13 days) PhysGen Knockout data heart pumping trait male 70 days-77 days 13 359.15 beats/min 6.27 22.6 radiotelemetry carotid artery 0 - 43441 421
SS-Sh2b3em1Mcwi-/- heart rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data heart pumping trait male 70 days-77 days 13 349.62 beats/min 7.36 26.54 radiotelemetry carotid artery 0 - 43519 421
SS-Sh2b3em1Mcwi-/- mean arterial blood pressure controlled sodium content diet (4 %) (for 11 days) PhysGen Knockout data arterial blood pressure trait male 70 days-77 days 12 1/3 systolic pressure + 2/3 diastolic pressure 124.25 mmHg 2.86 9.9 radiotelemetry carotid artery 0 - 43535 421
SS-Sh2b3em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70 days-77 days 16 10.41 mEq/d 0.37 1.48 automated urine analysis 0 - 43567 421
SS-Sh2b3em1Mcwi-/- blood B lymphocyte count controlled sodium chloride content diet (0.4 %) (for 42 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. B cell quantity not specified 63 days 4 4.0 x 10E6 cells/ml 0.3 0.6 flow cytometry method 0.0 0 n=4-7 106515 3031
SS-Sh2b3em1Mcwi-/- urine albumin excretion rate controlled sodium chloride content diet (0.4 %) (for 42 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. urine albumin amount not specified 63 days 6 3.6 mg/d 0.3 0.73 urine albumin analysis 0.0 0 n=6-8 106525 3031
SS-Sh2b3em1Mcwi-/- urine albumin excretion rate controlled sodium chloride content diet (0.4 %) (for 42 days) then controlled sodium chloride content diet (4 %) (for 21 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. urine albumin amount not specified 84 days 6 30.3 mg/d 7.0 17.15 urine albumin analysis 0.0 0 n=6-8 106529 3031
SS-Sh2b3em1Mcwi-/- kidney total CD45 positive leukocyte count controlled sodium chloride content diet (0.4 %) (for 21 days) then controlled sodium chloride content diet (4 %) (for 21 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. leukocyte quantity not specified 84 days 5 1.84 x 10E6 cells/ml 0.3 0.67 flow cytometry method 0.0 0 n=5-6 106534 3031
SS-Sh2b3em1Mcwi-/- urine creatinine excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine creatinine amount male 70 days-77 days 17 10.65 mg/d 0.36 1.49 automated urine analysis 0 - 43551 421
SS-Sh2b3em1Mcwi-/- right kidney wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data kidney mass male 70 days-77 days 13 1.35 g 0.03 0.12 post excision weight measurement 0 - 43599 421
SS-Sh2b3em1Mcwi-/- blood mononuclear cell count controlled sodium chloride content diet (0.4 %) (for 21 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. leukocyte quantity not specified 84 days 4 14.7 x 10E6 cells/ml 0.6 1.2 flow cytometry method 0.0 0 n=4-7 106511 3031
SS-Sh2b3em1Mcwi-/- blood regulatory T cell count to total T cell count ratio controlled sodium chloride content diet (0.4 %) (for 42 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. T cell quantity not specified 63 days 4 4.9 % 0.1 0.2 flow cytometry method 0.0 0 n=4-7 -tregs spleen % 106519 3031
SS-Sh2b3em1Mcwi-/- mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 70 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. arterial blood pressure trait not specified 70 days 6 15sec/min for 3 hrs/day for 7days 127.7 mmHg 2.0 4.9 vascular fluid filled catheter 0.0 0 n=6-8 106521 3031
SS-Sh2b3em1Mcwi-/- mean arterial blood pressure controlled sodium content diet (4 %) (for 12 days) PhysGen Knockout data arterial blood pressure trait male 70 days-77 days 10 1/3 systolic pressure + 2/3 diastolic pressure 125.6 mmHg 2.09 6.6 radiotelemetry carotid artery 0 - 43613 421