| SS/Jr |
heart left ventricle end-systolic area |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) |
Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. |
heart left ventricle size trait |
not specified |
0 days
| 6 |
|
0.25 |
cm2 |
0.07 |
0.17 |
echocardiography |
0.0 |
|
0 |
|
|
69602 |
749 |
| SS/Jr |
heart left ventricle end-diastolic area |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) |
Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. |
heart left ventricle size trait |
not specified |
0 days
| 6 |
|
0.62 |
cm2 |
0.11 |
0.27 |
echocardiography |
0.0 |
|
0 |
|
|
69596 |
749 |
| SS-Nppbem2Mcwi+/+ |
heart interventricular end-systolic septal wall thickness |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
28 days
| 5 |
|
0.82 |
mm |
0.07 |
0.16 |
echocardiography |
0.0 |
|
0 |
|
|
99563 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
168 days
| 5 |
|
1.86 |
mm |
0.04 |
0.09 |
echocardiography |
0.0 |
|
0 |
|
|
99570 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-diastolic diameter |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
28 days
| 5 |
|
5.7 |
mm |
0.36 |
0.8 |
echocardiography |
0.0 |
|
0 |
|
|
99573 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-diastolic diameter |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
252 days
| 6 |
|
7.83 |
mm |
0.3 |
0.73 |
echocardiography |
0.0 |
|
0 |
|
|
99581 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-diastolic posterior wall thickness |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
84 days
| 6 |
|
1.72 |
mm |
0.06 |
0.15 |
echocardiography |
0.0 |
|
0 |
|
|
99587 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic posterior wall thickness |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
252 days
| 5 |
|
1.85 |
mm |
0.14 |
0.31 |
echocardiography |
0.0 |
|
0 |
|
|
99592 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-diastolic posterior wall thickness |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
252 days
| 6 |
|
2.54 |
mm |
0.16 |
0.39 |
echocardiography |
0.0 |
|
0 |
|
|
99591 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart interventricular end-systolic septal wall thickness |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
56 days
| 5 |
|
2.51 |
mm |
0.08 |
0.18 |
echocardiography |
0.0 |
|
0 |
|
|
99595 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
168 days
| 5 |
|
3.19 |
mm |
0.12 |
0.27 |
echocardiography |
0.0 |
|
0 |
|
|
99600 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic diameter |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
84 days
| 10 |
|
3.98 |
mm |
0.45 |
1.42 |
echocardiography |
0.0 |
|
0 |
|
|
99608 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic diameter |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
252 days
| 5 |
|
5.46 |
mm |
0.37 |
0.83 |
echocardiography |
0.0 |
|
0 |
|
|
99612 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-systolic diameter |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
252 days
| 6 |
|
4.72 |
mm |
0.04 |
0.1 |
echocardiography |
0.0 |
|
0 |
|
|
99611 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-systolic posterior wall thickness |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
28 days
| 5 |
|
1.45 |
mm |
0.1 |
0.22 |
echocardiography |
0.0 |
|
0 |
|
|
99613 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic posterior wall thickness |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
84 days
| 10 |
|
3.29 |
mm |
0.19 |
0.6 |
echocardiography |
0.0 |
|
0 |
|
|
99618 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-systolic posterior wall thickness |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
252 days
| 6 |
|
3.77 |
mm |
0.11 |
0.27 |
echocardiography |
0.0 |
|
0 |
|
|
99621 |
2319 |
| SS-Nppbem2Mcwi+/+ |
ejection fraction |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
28 days
| 5 |
|
83.2 |
% |
7.2 |
16.1 |
echocardiography |
0.0 |
|
0 |
|
|
99623 |
2319 |
| SS-Nppbem2Mcwi+/+ |
ejection fraction |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
56 days
| 5 |
|
85.8 |
% |
2.8 |
6.26 |
echocardiography |
0.0 |
|
0 |
|
|
99625 |
2319 |
| WKY |
ejection fraction |
sham surgical control condition (for 224 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
cardiac output trait |
male |
266 days-280 days |
5 |
|
86.8 |
% |
1.5 |
3.35 |
echocardiography |
0.0 |
lad occlusion sham |
210 |
days |
|
100300 |
2460 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle weight |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
168 days
| 5 |
|
1.67 |
g |
0.03 |
0.07 |
echocardiography |
0.0 |
|
0 |
|
|
99675 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-diastolic diameter |
controlled sodium content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 4 |
|
8.75 |
mm |
0.66 |
1.32 |
echocardiography |
0.0 |
|
0 |
|
|
99712 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-diastolic septal wall thickness |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
84 days
| 6 |
|
1.42 |
mm |
0.08 |
0.2 |
echocardiography |
0.0 |
|
0 |
|
|
99763 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-diastolic septal wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
252 days
| 7 |
|
2.26 |
mm |
0.23 |
0.61 |
echocardiography |
0.0 |
|
0 |
|
|
99766 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic posterior wall thickness |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
84 days
| 6 |
|
1.54 |
mm |
0.17 |
0.42 |
echocardiography |
0.0 |
|
0 |
|
|
99775 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic posterior wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
168 days
| 7 |
|
1.89 |
mm |
0.16 |
0.42 |
echocardiography |
0.0 |
|
0 |
|
|
99776 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic diameter |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
84 days
| 7 |
|
3.98 |
mm |
0.45 |
1.19 |
echocardiography |
0.0 |
|
0 |
|
|
99786 |
2319 |
| SS.ZUC-Leprfa+/+/Slc |
heart ventricle septal wall thickness |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle wall thickness |
male |
91 days
| 10 |
|
0.18 |
cm |
0.0 |
0.01 |
echocardiography |
0.0 |
|
0 |
|
|
101784 |
2641 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle end-diastolic diameter |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle end-diastolic diameter |
male |
91 days
| 8 |
|
8.09 |
mm |
0.22 |
0.62 |
echocardiography |
0.0 |
|
0 |
|
|
101787 |
2641 |
| SS.ZUC-Leprfa+/+/Slc |
calculated heart left ventricle weight |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle mass |
male |
91 days
| 8 |
|
948.71 |
mg |
51.33 |
145.18 |
echocardiography |
0.0 |
|
0 |
|
|
101795 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
calculated heart left ventricle weight |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle mass |
male |
91 days
| 12 |
|
986.71 |
mg |
25.23 |
87.4 |
echocardiography |
0.0 |
|
0 |
|
|
101798 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle end-diastolic diameter |
atorvastatin (6 mg/kg/d) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle end-diastolic diameter |
male |
91 days
| 13 |
|
8.56 |
mm |
0.08 |
0.29 |
echocardiography |
0.0 |
|
0 |
|
|
101996 |
2644 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle fractional shortening |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
56 days
| 6 |
|
48.3 |
% |
8.1 |
19.84 |
echocardiography |
0.0 |
|
0 |
|
|
99636 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle fractional shortening |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
252 days
| 5 |
|
38.8 |
% |
2.6 |
5.81 |
echocardiography |
0.0 |
|
0 |
|
|
99642 |
2319 |
| Crl:WI |
heart left ventricle weight to body weight ratio |
control condition |
Korkmaz-Ic�z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. |
heart left ventricle mass |
male |
112 days
| 10 |
|
2.52 |
mg/g |
0.17 |
0.54 |
echocardiography |
0.0 |
|
0 |
|
|
102989 |
2783 |
| GK/MolTac |
heart left ventricle end-diastolic diameter to body weight ratio |
control condition |
Korkmaz-Ic�z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. |
heart left ventricle diameter |
male |
112 days
| 8 |
|
15.29 |
mm/kg |
0.51 |
1.44 |
echocardiography |
0.0 |
|
0 |
|
|
102996 |
2783 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic posterior wall thickness |
controlled sodium content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
98 days
| 4 |
|
1.87 |
mm |
0.2 |
0.4 |
echocardiography |
0.0 |
|
0 |
|
|
99715 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic posterior wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
84 days
| 7 |
|
2.03 |
mm |
0.06 |
0.16 |
echocardiography |
0.0 |
|
0 |
|
|
99774 |
2319 |
| GK/CskCrljCrl |
heart left ventricle weight to body weight ratio |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart left ventricle mass |
male |
168 days
| 4 |
|
2.84 |
mg/g |
0.18 |
0.36 |
echocardiography |
0.0 |
|
0 |
|
|
103114 |
2786 |
| Crl:WI |
E/A wave ratio |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
1.29 |
null |
0.06 |
0.11 |
echocardiography |
0.0 |
|
0 |
|
e/a wave |
103125 |
2786 |
| GK/CskCrljCrl |
E' wave velocity |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
36.26 |
mm/s |
6.77 |
13.54 |
echocardiography |
0.0 |
|
0 |
|
e' wave |
103128 |
2786 |
| Crl:WI |
E/E' wave ratio |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
23.4 |
null |
5.03 |
10.05 |
echocardiography |
0.0 |
|
0 |
|
e/e' wave |
103131 |
2786 |
| Crl:WI |
left ventricular isovolumetric relaxation time |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
19.09 |
ms |
1.55 |
3.1 |
echocardiography |
0.0 |
|
0 |
|
|
103137 |
2786 |
| Crl:WI |
left ventricular isovolumetric contraction time |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
10.98 |
ms |
0.49 |
0.98 |
echocardiography |
0.0 |
|
0 |
|
|
103133 |
2786 |
| SS-Nppbem2Mcwi-/- |
ejection fraction |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
84 days
| 6 |
|
80.4 |
% |
2.8 |
6.86 |
echocardiography |
0.0 |
|
0 |
|
|
99799 |
2319 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle end-diastolic diameter |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle end-diastolic diameter |
female |
91 days
| 7 |
|
7.1 |
mm |
0.12 |
0.32 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101718 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle fractional shortening |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle end-diastolic diameter |
female |
91 days
| 7 |
|
61.3 |
% |
2.7 |
7.14 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101722 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle relative wall thickness |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle wall thickness |
female |
91 days
| 9 |
|
44.0 |
% |
2.0 |
6.0 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101727 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
heart isovolumetric relaxation time |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart muscle relaxation trait |
female |
91 days
| 9 |
|
24.8 |
ms |
1.8 |
5.4 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101735 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
heart isovolumetric relaxation time |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart muscle relaxation trait |
female |
91 days
| 8 |
|
43.1 |
ms |
1.5 |
4.24 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101737 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
heart isovolumetric relaxation time |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart muscle relaxation trait |
female |
91 days
| 7 |
|
57.9 |
ms |
4.2 |
11.11 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101738 |
2622 |
| SD |
heart left ventricle end-systolic diameter |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
175 days
| 10 |
|
7.4 |
mm |
0.3 |
0.95 |
echocardiography |
0.0 |
ACF |
105 |
days |
|
99242 |
2278 |
| SD |
left ventricle end-diastolic wall stress |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
175 days
| 10 |
|
16.0 |
g/cm2 |
1.0 |
3.16 |
echocardiography |
0.0 |
ACF |
105 |
days |
|
99250 |
2278 |
| SD |
heart left ventricle end-diastolic diameter |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 7 |
|
7.7 |
mm |
0.2 |
0.53 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
99343 |
2278 |
| SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
lvedd/pw |
5.8 |
null |
0.2 |
0.45 |
echocardiography |
0.0 |
ACF |
2 |
days |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
99356 |
2278 |
| SD |
heart left ventricle fractional shortening |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
|
48.0 |
% |
5.0 |
11.18 |
echocardiography |
0.0 |
ACF |
2 |
days |
ledd/pw |
99364 |
2278 |
| SD |
heart left ventricle fractional shortening |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
|
37.0 |
% |
1.0 |
2.83 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
99368 |
2278 |
| SD |
ejection fraction |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
cardiac output trait |
male |
72 days
| 5 |
|
79.0 |
% |
3.0 |
6.71 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
99374 |
2278 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle fractional shortening |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
168 days
| 6 |
|
46.0 |
% |
8.3 |
20.33 |
echocardiography |
0.0 |
|
0 |
|
|
99807 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle fractional shortening |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
168 days
| 7 |
|
44.3 |
% |
2.8 |
7.41 |
echocardiography |
0.0 |
|
0 |
|
|
99806 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle fractional shortening |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
252 days
| 6 |
|
39.2 |
% |
5.8 |
14.21 |
echocardiography |
0.0 |
|
0 |
|
|
99809 |
2319 |
| SD |
ejection fraction |
sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
cardiac output trait |
male |
98 days
| 7 |
|
67.0 |
% |
2.0 |
5.29 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
99377 |
2278 |
| SD |
left ventricle end-diastolic wall stress |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
16.0 |
g/cm2 |
1.0 |
2.24 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
99388 |
2278 |
| WKY |
heart left ventricle end-diastolic diameter |
left anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-diastolic diameter |
male |
266 days-280 days |
16 |
|
10.8 |
mm |
0.3 |
1.2 |
echocardiography |
0.0 |
lad occlusion |
210 |
days |
|
100307 |
2460 |
| WKY |
heart left ventricle end-systolic diameter |
left anterior descending coronary artery occlusion (for 196 days) then vehicle control condition (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-systolic diameter |
male |
238 days-252 days |
30 |
|
8.9 |
mm |
0.2 |
1.1 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
|
100344 |
2460 |
| WKY |
heart left ventricle end-systolic diameter |
left anterior descending coronary artery occlusion (for 196 days) then furosemide (10 ml/kg/d) (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-systolic diameter |
male |
238 days-252 days |
20 |
|
9.0 |
mm |
0.2 |
0.89 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
|
100343 |
2460 |
| WKY |
heart left ventricle fractional shortening |
left anterior descending coronary artery occlusion (for 196 days) then furosemide (10 ml/kg/d) (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-diastolic diameter |
male |
238 days-252 days |
20 |
|
15.1 |
% |
1.0 |
4.47 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
|
100349 |
2460 |
| WKY |
ejection fraction |
left anterior descending coronary artery occlusion (for 196 days) then vehicle control condition (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
cardiac output trait |
male |
238 days-252 days |
30 |
|
37.0 |
% |
1.4 |
7.67 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
|
100353 |
2460 |
| SS.ZUC-Leprfa+/+/Slc |
E/A wave ratio |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
blood flow trait |
male |
91 days
| 10 |
|
1.72 |
null |
0.06 |
0.19 |
echocardiography |
0.0 |
|
0 |
|
|
101814 |
2641 |
| SS.ZUC-Leprfa+/+/Slc |
E wave deceleration time |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
blood flow trait |
male |
91 days
| 10 |
|
38.2 |
ms |
1.45 |
4.59 |
echocardiography |
0.0 |
|
0 |
|
|
101818 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
E/A wave ratio |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
blood flow trait |
male |
91 days
| 7 |
|
1.54 |
null |
0.13 |
0.34 |
echocardiography |
0.0 |
|
0 |
|
|
101815 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
heart isovolumetric relaxation time |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart muscle relaxation trait |
male |
91 days
| 7 |
|
38.35 |
ms |
1.84 |
4.87 |
echocardiography |
0.0 |
|
0 |
|
|
101823 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
time constant of left ventricular pressure decay |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricular blood pressure trait |
male |
91 days
| 12 |
|
28.77 |
ms |
1.73 |
5.99 |
echocardiography |
0.0 |
|
0 |
|
|
101828 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
heart posterior wall thickness |
vehicle control condition (0.5 %) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle posterior wall thickness |
male |
91 days
| 13 |
|
0.21 |
cm |
0.01 |
0.02 |
echocardiography |
0.0 |
|
0 |
|
|
101998 |
2644 |
| SS.ZUC-Leprfa-/-/Slc |
heart posterior wall thickness |
atorvastatin (20 mg/kg/d) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle posterior wall thickness |
male |
91 days
| 13 |
|
0.2 |
cm |
0.01 |
0.02 |
echocardiography |
0.0 |
|
0 |
|
|
102000 |
2644 |
| SS.ZUC-Leprfa-/-/Slc |
heart isovolumetric relaxation time |
vehicle control condition (0.5 %) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart muscle relaxation trait |
male |
91 days
| 13 |
|
40.75 |
ms |
2.42 |
8.73 |
echocardiography |
0.0 |
|
0 |
|
|
102016 |
2644 |
| SD-Myh7bem1Blar+/+ |
heart left ventricle fractional shortening |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart left ventricle end-diastolic diameter |
not specified |
84 days
| 0 |
|
72.52 |
% |
16.33 |
|
echocardiography |
0.0 |
|
0 |
|
SD-Myh7bem1Blar+/+ (RS:0005005) |
110945 |
3192 |
| SD-Myh7bem1Blar-/- |
heart interventricular end-diastolic septal wall thickness |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart ventricle septum thickness |
not specified |
84 days
| 0 |
|
2.58 |
mm |
0.4 |
|
echocardiography |
0.0 |
|
0 |
|
heart left ventricle end-systolic internal diameter (CMO:0003851) |
110956 |
3192 |
| SD-Myh7bem1Blar+/- |
heart left ventricle end-systolic posterior wall thickness |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart left ventricle posterior wall thickness |
not specified |
84 days
| 0 |
|
4.34 |
mm |
0.42 |
|
echocardiography |
0.0 |
|
0 |
|
|
110964 |
3192 |
| SD-Myh7bem1Blar+/+ |
heart left ventricle end-systolic posterior wall thickness |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart left ventricle posterior wall thickness |
not specified |
84 days
| 0 |
|
3.33 |
mm |
0.52 |
|
echocardiography |
0.0 |
|
0 |
|
|
110963 |
3192 |
| SD-Myh7bem1Blar-/- |
heart rate |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart pumping trait |
not specified |
84 days
| 0 |
|
391.7 |
beats/min |
47.0 |
|
echocardiography |
0.0 |
|
0 |
|
heart left ventricle end-systolic internal diameter (CMO:0003851) |
110968 |
3192 |
| SD-Myh7bem1Blar+/+ |
heart left ventricle end-systolic internal diameter |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart left ventricle end-systolic diameter |
not specified |
84 days
| 0 |
|
1.43 |
mm |
0.93 |
|
echocardiography |
0.0 |
|
0 |
|
heart left ventricle end-systolic internal diameter (CMO:0003851) |
110951 |
3192 |
| SS.SHR-(D9Mco72-D9Mco105)/Mco |
heart left ventricle end-systolic area |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) |
Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. |
heart left ventricle size trait |
not specified |
0 days
| 7 |
|
0.44 |
cm2 |
0.05 |
0.13 |
echocardiography |
0.0 |
|
0 |
|
|
69603 |
749 |
| WKY |
heart left ventricle fractional shortening |
sham surgical control condition (for 196 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-diastolic diameter |
male |
238 days-252 days |
12 |
|
41.1 |
% |
3.0 |
10.39 |
echocardiography |
0.0 |
lad occlusion sham |
196 |
days |
|
100348 |
2460 |
| SS.ZUC-Leprfa-/-/Slc |
heart isovolumetric relaxation time |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart muscle relaxation trait |
male |
91 days
| 12 |
|
34.39 |
ms |
1.07 |
3.71 |
echocardiography |
0.0 |
|
0 |
|
|
101824 |
2641 |
| SS-Nppbem2Mcwi-/- |
ejection fraction |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
56 days
| 6 |
|
85.2 |
% |
6.5 |
15.92 |
echocardiography |
0.0 |
|
0 |
|
|
99626 |
2319 |
| SD |
left ventricle end-diastolic wall stress |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
175 days
| 10 |
|
7.0 |
g/cm2 |
1.0 |
3.16 |
echocardiography |
0.0 |
sham ACF |
105 |
days |
|
99249 |
2278 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-diastolic septal wall thickness |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
168 days
| 6 |
|
1.9 |
mm |
0.2 |
0.49 |
echocardiography |
0.0 |
|
0 |
|
|
99765 |
2319 |
| SS.ZUC-Leprfa+/+/Slc |
heart ventricle septal wall thickness |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle wall thickness |
female |
91 days
| 12 |
|
0.15 |
cm |
0.0 |
0.01 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101708 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle end-diastolic diameter |
vehicle control condition (0.5 %) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle end-diastolic diameter |
male |
91 days
| 13 |
|
8.27 |
mm |
0.13 |
0.47 |
echocardiography |
0.0 |
|
0 |
|
|
101995 |
2644 |
| Crl:WI |
heart rate |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
370.33 |
beats/min |
15.6 |
31.2 |
echocardiography |
0.0 |
|
0 |
|
|
103093 |
2786 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic diameter |
controlled sodium content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
98 days
| 4 |
|
4.18 |
mm |
0.19 |
0.38 |
echocardiography |
0.0 |
|
0 |
|
|
99719 |
2319 |
| GK/CskCrljCrl |
A' wave velocity |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
52.27 |
mm/s |
5.98 |
11.95 |
echocardiography |
0.0 |
|
0 |
|
a' wave |
103130 |
2786 |
| SD |
heart left ventricle end-diastolic diameter |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
|
6.9 |
mm |
0.2 |
0.45 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
99339 |
2278 |
| SD |
heart left ventricle end-systolic diameter |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
72 days
| 5 |
|
4.1 |
mm |
0.2 |
0.45 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
99349 |
2278 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle fractional shortening |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
252 days
| 7 |
|
41.6 |
% |
5.6 |
14.82 |
echocardiography |
0.0 |
|
0 |
|
|
99808 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle weight |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
252 days
| 6 |
|
1.84 |
g |
0.08 |
0.2 |
echocardiography |
0.0 |
|
0 |
|
|
99815 |
2319 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle relative wall thickness |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle wall thickness |
male |
91 days
| 10 |
|
45.0 |
% |
2.0 |
6.32 |
echocardiography |
0.0 |
|
0 |
|
|
101802 |
2641 |
| SD |
left ventricle end-diastolic wall stress |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
6.0 |
g/cm2 |
1.0 |
2.24 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
99389 |
2278 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-diastolic posterior wall thickness |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
heart left ventricle posterior wall thickness |
female |
252 days
| 4 |
|
1.95 |
mm |
0.1 |
0.2 |
echocardiography |
0.0 |
|
0 |
|
|
101645 |
2621 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic diameter |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
heart left ventricle end-systolic diameter |
female |
252 days
| 5 |
|
4.12 |
mm |
0.21 |
0.47 |
echocardiography |
0.0 |
|
0 |
|
|
101650 |
2621 |
| SS-Nppbem2Mcwi-/- |
heart rate |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
28 days
| 7 |
|
344.0 |
beats/min |
43.0 |
113.77 |
echocardiography |
0.0 |
|
0 |
|
|
99554 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart rate |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
56 days
| 6 |
|
390.0 |
beats/min |
8.0 |
19.6 |
echocardiography |
0.0 |
|
0 |
|
|
99556 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart rate |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
84 days
| 10 |
|
382.0 |
beats/min |
45.0 |
142.3 |
echocardiography |
0.0 |
|
0 |
|
|
99558 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart rate |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
168 days
| 5 |
|
351.0 |
beats/min |
8.0 |
17.89 |
echocardiography |
0.0 |
|
0 |
|
|
99560 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart rate |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
252 days
| 6 |
|
342.0 |
beats/min |
5.0 |
12.25 |
echocardiography |
0.0 |
|
0 |
|
|
99561 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart interventricular end-systolic septal wall thickness |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
56 days
| 5 |
|
1.26 |
mm |
0.07 |
0.16 |
echocardiography |
0.0 |
|
0 |
|
IVSd |
99565 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
84 days
| 10 |
|
2.01 |
mm |
0.08 |
0.25 |
echocardiography |
0.0 |
|
0 |
|
|
99568 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic diameter |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
28 days
| 7 |
|
5.3 |
mm |
0.49 |
1.3 |
echocardiography |
0.0 |
|
0 |
|
|
99574 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic posterior wall thickness |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
56 days
| 6 |
|
1.27 |
mm |
0.13 |
0.32 |
echocardiography |
0.0 |
|
0 |
|
|
99586 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic posterior wall thickness |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
28 days
| 7 |
|
0.8 |
mm |
0.16 |
0.42 |
echocardiography |
0.0 |
|
0 |
|
|
99584 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart interventricular end-systolic septal wall thickness |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
28 days
| 5 |
|
1.82 |
mm |
0.23 |
0.51 |
echocardiography |
0.0 |
|
0 |
|
|
99593 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart interventricular end-systolic septal wall thickness |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
252 days
| 6 |
|
3.81 |
mm |
0.16 |
0.39 |
echocardiography |
0.0 |
|
0 |
|
|
99601 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-systolic diameter |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
56 days
| 5 |
|
4.21 |
mm |
0.41 |
0.92 |
echocardiography |
0.0 |
|
0 |
|
|
99605 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic diameter |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
28 days
| 7 |
|
2.4 |
mm |
0.45 |
1.19 |
echocardiography |
0.0 |
|
0 |
|
|
99604 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-systolic diameter |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
84 days
| 6 |
|
3.98 |
mm |
0.16 |
0.39 |
echocardiography |
0.0 |
|
0 |
|
|
99607 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-systolic diameter |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
168 days
| 5 |
|
4.51 |
mm |
0.13 |
0.29 |
echocardiography |
0.0 |
|
0 |
|
|
99609 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic posterior wall thickness |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
168 days
| 5 |
|
3.01 |
mm |
0.05 |
0.11 |
echocardiography |
0.0 |
|
0 |
|
|
99620 |
2319 |
| WKY |
ejection fraction |
left anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) then ramipril (1 mg/kg/d) (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
cardiac output trait |
male |
266 days-280 days |
32 |
|
40.5 |
% |
2.4 |
13.58 |
echocardiography |
0.0 |
lad occlusion |
210 |
days |
|
100302 |
2460 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle weight |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
56 days
| 5 |
|
1.16 |
g |
0.04 |
0.09 |
echocardiography |
0.0 |
|
0 |
|
|
99670 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle weight |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
56 days
| 6 |
|
1.15 |
g |
0.02 |
0.05 |
echocardiography |
0.0 |
|
0 |
|
|
99671 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle weight |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
84 days
| 10 |
|
1.53 |
g |
0.08 |
0.25 |
echocardiography |
0.0 |
|
0 |
|
|
99673 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
252 days
| 6 |
|
3.52 |
mm |
0.21 |
0.51 |
echocardiography |
0.0 |
|
0 |
|
|
99785 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic diameter |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
84 days
| 6 |
|
4.64 |
mm |
0.36 |
0.88 |
echocardiography |
0.0 |
|
0 |
|
|
99787 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic diameter |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
168 days
| 7 |
|
4.83 |
mm |
0.35 |
0.93 |
echocardiography |
0.0 |
|
0 |
|
|
99788 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic diameter |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
252 days
| 7 |
|
4.67 |
mm |
0.74 |
1.96 |
echocardiography |
0.0 |
|
0 |
|
|
99790 |
2319 |
| SS.ZUC-Leprfa-/-/Slc |
heart ventricle septal wall thickness |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle wall thickness |
male |
91 days
| 12 |
|
0.16 |
cm |
0.0 |
0.01 |
echocardiography |
0.0 |
|
0 |
|
|
101786 |
2641 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle posterior wall thickness |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle posterior wall thickness |
male |
91 days
| 8 |
|
1.56 |
mm |
0.09 |
0.25 |
echocardiography |
0.0 |
|
0 |
|
|
101791 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle posterior wall thickness |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle posterior wall thickness |
male |
91 days
| 12 |
|
1.68 |
mm |
0.05 |
0.17 |
echocardiography |
0.0 |
|
0 |
|
|
101794 |
2641 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic posterior wall thickness |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
84 days
| 6 |
|
2.62 |
mm |
0.2 |
0.49 |
echocardiography |
0.0 |
|
0 |
|
|
99793 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-systolic posterior wall thickness |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
heart left ventricle posterior wall thickness |
female |
252 days
| 4 |
|
3.08 |
mm |
0.09 |
0.18 |
echocardiography |
0.0 |
|
0 |
|
|
101651 |
2621 |
| SS-Nppbem2Mcwi-/- |
ejection fraction |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
cardiac output trait |
female |
252 days
| 5 |
|
85.0 |
% |
1.9 |
4.25 |
echocardiography |
0.0 |
|
0 |
|
|
101654 |
2621 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle weight |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
heart left ventricle mass |
female |
252 days
| 5 |
|
1.44 |
g |
0.03 |
0.07 |
echocardiography |
0.0 |
|
0 |
|
|
101658 |
2621 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle fractional shortening |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
heart left ventricle end-diastolic diameter |
female |
252 days
| 5 |
|
47.4 |
% |
2.4 |
5.37 |
echocardiography |
0.0 |
|
0 |
|
|
101656 |
2621 |
| SS-Nppbem2Mcwi+/+ |
heart rate |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
heart pumping trait |
female |
252 days
| 4 |
|
321.0 |
beats/min |
10.0 |
20.0 |
echocardiography |
0.0 |
|
0 |
|
|
101659 |
2621 |
| SS.ZUC-Leprfa-/-/Slc |
heart ventricle septal wall thickness |
atorvastatin (20 mg/kg/d) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle wall thickness |
male |
91 days
| 13 |
|
0.2 |
cm |
0.0 |
0.01 |
echocardiography |
0.0 |
|
0 |
|
|
101994 |
2644 |
| Crl:WI |
heart left ventricle end-diastolic posterior wall index |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart left ventricle posterior wall thickness |
male |
168 days
| 4 |
|
3.69 |
mm/kg |
0.28 |
0.56 |
echocardiography |
0.0 |
|
0 |
|
|
103105 |
2786 |
| GK/CskCrljCrl |
heart left ventricle end-systolic posterior wall index |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart left ventricle posterior wall thickness |
male |
168 days
| 4 |
|
7.35 |
mm/kg |
0.65 |
1.29 |
echocardiography |
0.0 |
|
0 |
|
|
103108 |
2786 |
| GK/CskCrljCrl |
heart left ventricle end-systolic diameter to body weight ratio |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart left ventricle end-systolic diameter |
male |
168 days
| 4 |
|
13.6 |
mm/kg |
1.35 |
2.7 |
echocardiography |
0.0 |
|
0 |
|
mm/kg |
103112 |
2786 |
| SS-Nppbem2Mcwi-/- |
ejection fraction |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
252 days
| 5 |
|
74.2 |
% |
3.4 |
7.6 |
echocardiography |
0.0 |
|
0 |
|
|
99632 |
2319 |
| GK/MolTac |
heart left ventricle end-diastolic anterior wall index |
control condition |
Korkmaz-Ic�z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. |
heart left ventricle anterior wall thickness |
male |
112 days
| 8 |
|
7.31 |
mm/kg |
0.22 |
0.62 |
echocardiography |
0.0 |
|
0 |
|
|
102994 |
2783 |
| Crl:WI |
heart left ventricle end-diastolic anterior wall index |
control condition |
Korkmaz-Ic�z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. |
heart left ventricle anterior wall thickness |
male |
112 days
| 10 |
|
4.94 |
mm/kg |
0.15 |
0.47 |
echocardiography |
0.0 |
|
0 |
|
|
102993 |
2783 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-systolic diameter |
controlled sodium content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
98 days
| 4 |
|
5.26 |
mm |
0.65 |
1.3 |
echocardiography |
0.0 |
|
0 |
|
|
99718 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-systolic posterior wall thickness |
controlled sodium content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
98 days
| 4 |
|
2.51 |
mm |
0.23 |
0.46 |
echocardiography |
0.0 |
|
0 |
|
|
99720 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic posterior wall thickness |
controlled sodium content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
98 days
| 4 |
|
3.18 |
mm |
0.33 |
0.66 |
echocardiography |
0.0 |
|
0 |
|
|
99721 |
2319 |
| SS-Nppbem2Mcwi-/- |
ejection fraction |
controlled sodium chloride content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
98 days
| 4 |
|
83.0 |
% |
1.41 |
2.82 |
echocardiography |
0.0 |
|
0 |
|
|
99723 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle weight |
controlled sodium chloride content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
98 days
| 4 |
|
1.47 |
g |
0.11 |
0.22 |
echocardiography |
0.0 |
|
0 |
|
|
99726 |
2319 |
| SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
lvedd/pw |
4.6 |
null |
0.3 |
0.67 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
99357 |
2278 |
| GK/CskCrljCrl |
heart ventricle end-diastolic septal wall index |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart ventricle septum thickness |
male |
168 days
| 4 |
|
4.8 |
mm/kg |
0.47 |
0.93 |
echocardiography |
0.0 |
|
0 |
|
|
103116 |
2786 |
| GK/CskCrljCrl |
heart left ventricle fractional shortening |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart left ventricle end-diastolic diameter |
male |
168 days
| 4 |
|
38.2 |
% |
4.45 |
8.89 |
echocardiography |
0.0 |
|
0 |
|
|
103120 |
2786 |
| GK/CskCrljCrl |
myocardial performance index |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
0.57 |
null |
0.06 |
0.11 |
echocardiography |
0.0 |
|
0 |
|
|
103140 |
2786 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle posterior wall thickness |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle posterior wall thickness |
female |
91 days
| 12 |
|
1.4 |
mm |
0.02 |
0.07 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101712 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle posterior wall thickness |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle posterior wall thickness |
female |
91 days
| 7 |
|
2.16 |
mm |
0.06 |
0.16 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101714 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle end-diastolic diameter |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle end-diastolic diameter |
female |
91 days
| 8 |
|
7.2 |
mm |
0.14 |
0.4 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101717 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
calculated heart left ventricle weight |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle mass |
female |
91 days
| 12 |
|
589.0 |
mg |
31.0 |
107.39 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101724 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
calculated heart left ventricle weight |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle mass |
female |
91 days
| 8 |
|
1114.0 |
mg |
35.0 |
98.99 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101725 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
E wave deceleration time |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart pumping trait |
female |
91 days
| 12 |
|
53.6 |
ms |
1.4 |
4.85 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101732 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
time constant of left ventricular pressure decay |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricular blood pressure trait |
female |
91 days
| 7 |
|
62.4 |
ms |
3.3 |
8.73 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101750 |
2622 |
| SD |
heart left ventricle end-systolic diameter |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
98 days
| 8 |
|
4.3 |
mm |
0.3 |
0.85 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
99239 |
2278 |
| SD |
heart left ventricle end-systolic diameter |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
175 days
| 10 |
|
5.6 |
mm |
0.1 |
0.32 |
echocardiography |
0.0 |
sham ACF |
105 |
days |
|
99241 |
2278 |
| SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
lvedd/pw |
7.7 |
null |
0.5 |
1.41 |
echocardiography |
0.0 |
ACF |
28 |
days |
heart left ventricle end-diastolic dimeter to posterior wall thickness ratio |
99244 |
2278 |
| SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
lvedd/pw |
4.8 |
null |
0.3 |
0.85 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
heart left ventricle end-diastolic dimeter to posterior wall thickness ratio |
99243 |
2278 |
| SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
175 days
| 10 |
lvedd/pw |
5.9 |
null |
0.3 |
0.95 |
echocardiography |
0.0 |
sham ACF |
105 |
days |
heart left ventricle end-diastolic dimeter to posterior wall thickness ratio |
99245 |
2278 |
| SD |
left ventricle end-systolic wall stress |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
77.0 |
g/cm2 |
8.0 |
22.63 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
99252 |
2278 |
| SD |
heart left ventricle fractional shortening |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
175 days
| 10 |
|
34.0 |
% |
2.0 |
6.32 |
echocardiography |
0.0 |
ACF |
105 |
days |
|
99258 |
2278 |
| SD |
heart left ventricle end-diastolic diameter |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
|
8.0 |
mm |
0.1 |
0.22 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
99342 |
2278 |
| SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
lvedd/pw |
6.0 |
null |
0.4 |
1.13 |
echocardiography |
0.0 |
ACF |
28 |
days |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
99362 |
2278 |
| SD |
heart left ventricle fractional shortening |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
|
41.0 |
% |
2.0 |
4.47 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
ledd/pw |
99363 |
2278 |
| SD |
ejection fraction |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
cardiac output trait |
male |
72 days
| 5 |
|
72.0 |
% |
2.0 |
4.47 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
99373 |
2278 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle fractional shortening |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
84 days
| 6 |
|
44.3 |
% |
2.9 |
7.1 |
echocardiography |
0.0 |
|
0 |
|
|
99805 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart rate |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
252 days
| 6 |
|
342.5 |
beats/min |
20.0 |
48.99 |
echocardiography |
0.0 |
|
0 |
|
|
99821 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart rate |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
168 days
| 6 |
|
348.0 |
beats/min |
19.0 |
46.54 |
echocardiography |
0.0 |
|
0 |
|
|
99819 |
2319 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle relative wall thickness |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle wall thickness |
male |
91 days
| 7 |
|
57.0 |
% |
4.0 |
10.58 |
echocardiography |
0.0 |
|
0 |
|
|
101803 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle relative wall thickness |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle wall thickness |
male |
91 days
| 12 |
|
41.0 |
% |
1.0 |
3.46 |
echocardiography |
0.0 |
|
0 |
|
|
101804 |
2641 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle fractional shortening |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle end-diastolic diameter |
male |
91 days
| 8 |
|
32.62 |
% |
1.67 |
4.72 |
echocardiography |
0.0 |
|
0 |
|
|
101805 |
2641 |
| SD |
left ventricle end-diastolic wall stress |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
4.0 |
g/cm2 |
1.0 |
2.24 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
lved-ws |
99387 |
2278 |
| SD |
left ventricle end-systolic wall stress |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 7 |
|
65.0 |
g/cm2 |
5.0 |
13.23 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
99399 |
2278 |
| WKY |
heart left ventricle end-systolic diameter |
sham surgical control condition (for 224 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-systolic diameter |
male |
266 days-280 days |
5 |
|
3.8 |
mm |
0.3 |
0.67 |
echocardiography |
0.0 |
lad occlusion sham |
210 |
days |
|
100309 |
2460 |
| WKY |
heart rate |
sham surgical control condition (for 224 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart pumping trait |
male |
266 days-280 days |
5 |
|
398.0 |
beats/min |
37.0 |
82.73 |
echocardiography |
0.0 |
lad occlusion sham |
210 |
days |
|
100312 |
2460 |
| WKY |
heart left ventricle end-systolic diameter |
left anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) then ramipril (1 mg/kg/d) (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-systolic diameter |
male |
266 days-280 days |
32 |
|
8.8 |
mm |
0.3 |
1.7 |
echocardiography |
0.0 |
lad occlusion |
210 |
days |
|
100311 |
2460 |
| WKY |
heart left ventricle end-systolic diameter |
sham surgical control condition (for 196 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-systolic diameter |
male |
238 days-252 days |
12 |
|
4.9 |
mm |
0.3 |
1.04 |
echocardiography |
0.0 |
lad occlusion sham |
196 |
days |
|
100342 |
2460 |
| WKY |
heart left ventricle end-diastolic diameter |
left anterior descending coronary artery occlusion (for 196 days) then furosemide (10 ml/kg/d) (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-diastolic diameter |
male |
238 days-252 days |
20 |
|
10.6 |
mm |
0.2 |
0.89 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
|
100340 |
2460 |
| WKY |
ejection fraction |
sham surgical control condition (for 196 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
cardiac output trait |
male |
238 days-252 days |
12 |
|
75.8 |
% |
3.9 |
13.51 |
echocardiography |
0.0 |
lad occlusion sham |
196 |
days |
|
100351 |
2460 |
| WKY |
ejection fraction |
left anterior descending coronary artery occlusion (for 196 days) then furosemide (10 ml/kg/d) (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
cardiac output trait |
male |
238 days-252 days |
20 |
|
35.5 |
% |
2.0 |
8.94 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
|
100352 |
2460 |
| WKY |
E/A wave ratio |
sham surgical control condition (for 196 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
blood flow trait |
male |
238 days-252 days |
12 |
|
1.39 |
null |
0.15 |
0.52 |
echocardiography |
0.0 |
lad occlusion sham |
196 |
days |
e/a wave |
100354 |
2460 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle fractional shortening |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle end-diastolic diameter |
male |
91 days
| 10 |
|
35.33 |
% |
1.87 |
5.91 |
echocardiography |
0.0 |
|
0 |
|
|
101806 |
2641 |
| SS.ZUC-Leprfa+/+/Slc |
heart isovolumetric relaxation time |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart muscle relaxation trait |
male |
91 days
| 10 |
|
31.43 |
ms |
1.47 |
4.65 |
echocardiography |
0.0 |
|
0 |
|
|
101822 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
heart posterior wall thickness |
atorvastatin (6 mg/kg/d) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle posterior wall thickness |
male |
91 days
| 13 |
|
0.2 |
cm |
0.0 |
0.01 |
echocardiography |
0.0 |
|
0 |
|
|
101999 |
2644 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle fractional shortening |
atorvastatin (20 mg/kg/d) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle end-diastolic diameter |
male |
91 days
| 13 |
|
44.28 |
% |
1.6 |
5.77 |
echocardiography |
0.0 |
|
0 |
|
|
102009 |
2644 |
| SS.ZUC-Leprfa-/-/Slc |
ejection fraction |
vehicle control condition (0.5 %) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
cardiac output trait |
male |
91 days
| 13 |
|
82.5 |
% |
1.94 |
6.99 |
echocardiography |
0.0 |
|
0 |
|
|
102010 |
2644 |
| SS-Plekha7em4Mcwi-/- |
heart ventricle septal wall thickness |
controlled sodium content diet (8 %) (for 28 days) |
Endres BT, et al., Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12817-22. doi: 10.1073/pnas.1410745111. Epub 2014 Aug 18. |
heart left ventricle wall thickness |
male |
91 days
| 10 |
|
0.25 |
cm |
0.01 |
0.03 |
echocardiography |
0.0 |
|
0 |
|
|
105757 |
3022 |
| SD-Myh7bem1Blar-/- |
heart left ventricle fractional shortening |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart left ventricle end-diastolic diameter |
not specified |
84 days
| 0 |
|
81.02 |
% |
10.01 |
|
echocardiography |
0.0 |
|
0 |
|
|
110946 |
3192 |
| SD-Myh7bem1Blar+/+ |
heart left ventricle end-diastolic posterior wall thickness |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart left ventricle posterior wall thickness |
not specified |
84 days
| 0 |
|
1.93 |
mm |
0.28 |
|
echocardiography |
0.0 |
|
0 |
|
|
110960 |
3192 |
| SD-Myh7bem1Blar+/- |
heart left ventricle end-systolic internal diameter |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart left ventricle end-systolic diameter |
not specified |
84 days
| 0 |
|
0.36 |
mm |
0.32 |
|
echocardiography |
0.0 |
|
0 |
|
heart left ventricle end-systolic internal diameter (CMO:0003851) |
110952 |
3192 |
| SD-Myh7bem1Blar-/- |
ejection fraction |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
cardiac output trait |
not specified |
84 days
| 0 |
|
97.65 |
% |
2.63 |
|
echocardiography |
0.0 |
|
0 |
|
|
110841 |
3192 |
| SD-Myh7bem1Blar+/- |
heart left ventricle fractional shortening |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart left ventricle end-diastolic diameter |
not specified |
84 days
| 0 |
|
84.34 |
% |
11.12 |
|
echocardiography |
0.0 |
|
0 |
|
|
110947 |
3192 |
| SS/Jr |
heart ventricle septal wall thickness |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) |
Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. |
heart left ventricle wall thickness |
not specified |
0 days
| 6 |
|
0.26 |
cm |
0.02 |
0.05 |
echocardiography |
0.0 |
|
0 |
|
|
69606 |
749 |
| SD |
left ventricle end-systolic wall stress |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
81.0 |
g/cm2 |
8.0 |
22.63 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
99400 |
2278 |
| SS-Plekha7em4Mcwi+/+ |
heart ventricle septal wall thickness |
controlled sodium content diet (8 %) (for 28 days) |
Endres BT, et al., Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12817-22. doi: 10.1073/pnas.1410745111. Epub 2014 Aug 18. |
heart left ventricle wall thickness |
male |
91 days
| 10 |
|
0.17 |
cm |
0.01 |
0.03 |
echocardiography |
0.0 |
|
0 |
|
|
105756 |
3022 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic posterior wall thickness |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
heart left ventricle posterior wall thickness |
female |
252 days
| 5 |
|
1.81 |
mm |
0.07 |
0.16 |
echocardiography |
0.0 |
|
0 |
|
|
101646 |
2621 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-diastolic septal wall thickness |
controlled sodium content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
98 days
| 4 |
|
1.81 |
mm |
0.19 |
0.38 |
echocardiography |
0.0 |
|
0 |
|
|
99711 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic posterior wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
84 days
| 7 |
|
3.29 |
mm |
0.19 |
0.5 |
echocardiography |
0.0 |
|
0 |
|
|
99792 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle weight |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
heart left ventricle mass |
female |
252 days
| 4 |
|
1.46 |
g |
0.02 |
0.04 |
echocardiography |
0.0 |
|
0 |
|
|
101657 |
2621 |
| GK/MolTac |
heart left ventricle end-diastolic posterior wall index |
control condition |
Korkmaz-Ic�z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. |
heart left ventricle posterior wall thickness |
male |
112 days
| 8 |
|
8.85 |
mm/kg |
0.31 |
0.88 |
echocardiography |
0.0 |
|
0 |
|
|
102992 |
2783 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic diameter |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
168 days
| 7 |
|
8.68 |
mm |
0.33 |
0.87 |
echocardiography |
0.0 |
|
0 |
|
|
99770 |
2319 |
| Crl:WI |
heart ventricle end-systolic septal wall index |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart ventricle septum thickness |
male |
168 days
| 4 |
|
6.58 |
mm/kg |
0.48 |
0.96 |
echocardiography |
0.0 |
|
0 |
|
|
103117 |
2786 |
| Crl:WI |
E' wave velocity |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
54.43 |
mm/s |
8.1 |
16.2 |
echocardiography |
0.0 |
|
0 |
|
e' wave |
103127 |
2786 |
| GK/CskCrljCrl |
A wave velocity |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
560.5 |
mm/s |
38.94 |
77.88 |
echocardiography |
0.0 |
|
0 |
|
a wave |
103124 |
2786 |
| SD |
heart left ventricle end-diastolic diameter |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
|
10.6 |
mm |
0.3 |
0.85 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
99344 |
2278 |
| SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 7 |
lvedd/pw |
4.5 |
null |
0.4 |
1.06 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
99361 |
2278 |
| SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
lvedd/pw |
5.4 |
null |
0.4 |
0.89 |
echocardiography |
0.0 |
ACF |
2 |
days |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
99358 |
2278 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle weight |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
168 days
| 7 |
|
1.67 |
g |
0.06 |
0.16 |
echocardiography |
0.0 |
|
0 |
|
|
99812 |
2319 |
| SD |
left ventricle end-systolic wall stress |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
49.0 |
g/cm2 |
9.0 |
20.12 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
99397 |
2278 |
| WKY |
heart rate |
left anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart pumping trait |
male |
266 days-280 days |
16 |
|
362.0 |
beats/min |
31.0 |
124.0 |
echocardiography |
0.0 |
lad occlusion |
210 |
days |
|
100313 |
2460 |
| WKY |
heart left ventricle fractional shortening |
sham surgical control condition (for 224 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-diastolic diameter |
male |
266 days-280 days |
5 |
|
51.5 |
% |
1.7 |
3.8 |
echocardiography |
0.0 |
lad occlusion sham |
210 |
days |
|
100303 |
2460 |
| WKY |
heart ventricle septal wall thickness |
left anterior descending coronary artery occlusion (for 196 days) then vehicle control condition (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle wall thickness |
male |
238 days-252 days |
30 |
|
0.1 |
cm |
0.0 |
0.02 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
|
100338 |
2460 |
| SS/Jr |
heart left ventricle posterior wall thickness |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) |
Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. |
heart left ventricle posterior wall thickness |
not specified |
0 days
| 6 |
|
2.9 |
mm |
0.3 |
0.73 |
echocardiography |
0.0 |
|
0 |
|
|
69604 |
749 |
| SS.SHR-(D9Mco72-D9Mco105)/Mco |
heart ventricle septal wall thickness |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) |
Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. |
heart left ventricle wall thickness |
not specified |
0 days
| 7 |
|
0.2 |
cm |
0.01 |
0.03 |
echocardiography |
0.0 |
|
0 |
|
|
69607 |
749 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic diameter |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
heart left ventricle end-diastolic diameter |
female |
252 days
| 5 |
|
7.81 |
mm |
0.06 |
0.13 |
echocardiography |
0.0 |
|
0 |
|
|
101644 |
2621 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-diastolic septal wall thickness |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
heart ventricle septum thickness |
female |
252 days
| 5 |
|
1.8 |
mm |
0.04 |
0.09 |
echocardiography |
0.0 |
|
0 |
|
IVSd |
101642 |
2621 |
| SS-Nppbem2Mcwi+/+ |
heart interventricular end-diastolic septal wall thickness |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
heart ventricle septum thickness |
female |
252 days
| 4 |
|
1.98 |
mm |
0.04 |
0.08 |
echocardiography |
0.0 |
|
0 |
|
IVSd |
101641 |
2621 |
| SS-Nppbem2Mcwi+/+ |
heart rate |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
56 days
| 5 |
|
367.0 |
beats/min |
19.0 |
42.49 |
echocardiography |
0.0 |
|
0 |
|
|
99555 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart rate |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
252 days
| 5 |
|
347.0 |
beats/min |
4.0 |
8.94 |
echocardiography |
0.0 |
|
0 |
|
|
99562 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
252 days
| 5 |
|
2.27 |
mm |
0.07 |
0.16 |
echocardiography |
0.0 |
|
0 |
|
|
99572 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-diastolic diameter |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
84 days
| 6 |
|
7.53 |
mm |
0.07 |
0.17 |
echocardiography |
0.0 |
|
0 |
|
|
99577 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-diastolic diameter |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
56 days
| 5 |
|
8.11 |
mm |
0.35 |
0.78 |
echocardiography |
0.0 |
|
0 |
|
|
99575 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic diameter |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
168 days
| 5 |
|
8.84 |
mm |
0.09 |
0.2 |
echocardiography |
0.0 |
|
0 |
|
|
99580 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic diameter |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
252 days
| 5 |
|
8.88 |
mm |
0.22 |
0.49 |
echocardiography |
0.0 |
|
0 |
|
|
99582 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic posterior wall thickness |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
168 days
| 5 |
|
1.81 |
mm |
0.09 |
0.2 |
echocardiography |
0.0 |
|
0 |
|
|
99590 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
28 days
| 7 |
|
1.95 |
mm |
0.33 |
0.87 |
echocardiography |
0.0 |
|
0 |
|
|
99594 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart interventricular end-systolic septal wall thickness |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
84 days
| 6 |
|
2.85 |
mm |
0.13 |
0.32 |
echocardiography |
0.0 |
|
0 |
|
|
99597 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-systolic diameter |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
28 days
| 5 |
|
3.09 |
mm |
0.61 |
1.36 |
echocardiography |
0.0 |
|
0 |
|
|
99603 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic posterior wall thickness |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
56 days
| 6 |
|
2.34 |
mm |
0.56 |
1.37 |
echocardiography |
0.0 |
|
0 |
|
|
99616 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-systolic posterior wall thickness |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
84 days
| 6 |
|
2.9 |
mm |
0.07 |
0.17 |
echocardiography |
0.0 |
|
0 |
|
|
99617 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-systolic posterior wall thickness |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
168 days
| 5 |
|
3.29 |
mm |
0.13 |
0.29 |
echocardiography |
0.0 |
|
0 |
|
|
99619 |
2319 |
| SS-Nppbem2Mcwi-/- |
ejection fraction |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
168 days
| 5 |
|
79.0 |
% |
1.6 |
3.58 |
echocardiography |
0.0 |
|
0 |
|
|
99630 |
2319 |
| SS-Nppbem2Mcwi-/- |
ejection fraction |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
84 days
| 10 |
|
83.3 |
% |
4.3 |
13.6 |
echocardiography |
0.0 |
|
0 |
|
|
99628 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle weight |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
84 days
| 6 |
|
1.34 |
g |
0.04 |
0.1 |
echocardiography |
0.0 |
|
0 |
|
|
99672 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic diameter |
controlled sodium content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 4 |
|
8.17 |
mm |
0.32 |
0.64 |
echocardiography |
0.0 |
|
0 |
|
|
99713 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-diastolic septal wall thickness |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
252 days
| 6 |
|
2.36 |
mm |
0.2 |
0.49 |
echocardiography |
0.0 |
|
0 |
|
|
99767 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic posterior wall thickness |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
252 days
| 6 |
|
1.94 |
mm |
0.2 |
0.49 |
echocardiography |
0.0 |
|
0 |
|
|
99779 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
84 days
| 6 |
|
2.69 |
mm |
0.06 |
0.15 |
echocardiography |
0.0 |
|
0 |
|
|
99781 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
168 days
| 6 |
|
3.18 |
mm |
0.34 |
0.83 |
echocardiography |
0.0 |
|
0 |
|
|
99783 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic diameter |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
252 days
| 6 |
|
5.18 |
mm |
0.51 |
1.25 |
echocardiography |
0.0 |
|
0 |
|
|
99791 |
2319 |
| SS.ZUC-Leprfa-/-/Slc |
heart ventricle septal wall thickness |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle wall thickness |
male |
91 days
| 7 |
|
0.21 |
cm |
0.01 |
0.03 |
echocardiography |
0.0 |
|
0 |
|
|
101785 |
2641 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle fractional shortening |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
56 days
| 5 |
|
48.0 |
% |
3.9 |
8.72 |
echocardiography |
0.0 |
|
0 |
|
|
99635 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle fractional shortening |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
84 days
| 6 |
|
47.0 |
% |
2.1 |
5.14 |
echocardiography |
0.0 |
|
0 |
|
|
99637 |
2319 |
| GK/MolTac |
heart left ventricle weight to body weight ratio |
control condition |
Korkmaz-Ic�z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. |
heart left ventricle mass |
male |
112 days
| 8 |
|
3.41 |
mg/g |
0.17 |
0.48 |
echocardiography |
0.0 |
|
0 |
|
|
102990 |
2783 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
controlled sodium content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
98 days
| 4 |
|
3.31 |
mm |
0.19 |
0.38 |
echocardiography |
0.0 |
|
0 |
|
|
99717 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle weight |
controlled sodium chloride content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
98 days
| 4 |
|
1.53 |
g |
0.09 |
0.18 |
echocardiography |
0.0 |
|
0 |
|
|
99727 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic diameter |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
168 days
| 6 |
|
8.33 |
mm |
0.64 |
1.57 |
echocardiography |
0.0 |
|
0 |
|
|
99771 |
2319 |
| Crl:WI |
heart ventricle end-diastolic septal wall index |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart ventricle septum thickness |
male |
168 days
| 4 |
|
4.03 |
mm/kg |
0.31 |
0.62 |
echocardiography |
0.0 |
|
0 |
|
|
103115 |
2786 |
| GK/CskCrljCrl |
E wave velocity |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
818.5 |
mm/s |
39.05 |
78.1 |
echocardiography |
0.0 |
|
0 |
|
mm/s |
103122 |
2786 |
| GK/CskCrljCrl |
E/A wave ratio |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
1.49 |
null |
0.14 |
0.29 |
echocardiography |
0.0 |
|
0 |
|
e/a wave |
103126 |
2786 |
| GK/CskCrljCrl |
left ventricular isovolumetric contraction time |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
12.26 |
ms |
0.63 |
1.25 |
echocardiography |
0.0 |
|
0 |
|
|
103134 |
2786 |
| SS-Nppbem2Mcwi-/- |
ejection fraction |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
84 days
| 7 |
|
83.3 |
% |
4.3 |
11.38 |
echocardiography |
0.0 |
|
0 |
|
|
99798 |
2319 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle fractional shortening |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle end-diastolic diameter |
female |
91 days
| 9 |
|
39.8 |
% |
2.5 |
7.5 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101719 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
E wave deceleration time |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart pumping trait |
female |
91 days
| 9 |
|
35.4 |
ms |
1.2 |
3.6 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101731 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
myocardial performance index |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart pumping trait |
female |
91 days
| 9 |
|
0.44 |
null |
0.01 |
0.03 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101739 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
time constant of left ventricular pressure decay |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricular blood pressure trait |
female |
91 days
| 8 |
|
47.3 |
ms |
1.5 |
4.24 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101749 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricular end-diastolic blood pressure to heart left ventricular end-diastolic diameter ratio |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricular blood pressure trait |
female |
91 days
| 7 |
|
0.81 |
mmHg/mm |
0.03 |
0.08 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101754 |
2622 |
| SD |
heart left ventricle end-diastolic diameter |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
175 days
| 10 |
|
9.0 |
mm |
0.1 |
0.32 |
echocardiography |
0.0 |
sham ACF |
105 |
days |
|
99237 |
2278 |
| SD |
heart left ventricle end-diastolic diameter |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
|
7.0 |
mm |
0.2 |
0.57 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
99235 |
2278 |
| SD |
heart left ventricle end-systolic diameter |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
98 days
| 8 |
|
6.3 |
mm |
0.3 |
0.85 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
99240 |
2278 |
| SD |
left ventricle end-systolic wall stress |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
67.0 |
g/cm2 |
13.0 |
36.77 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
99251 |
2278 |
| SD |
left ventricle end-diastolic wall stress |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
3.0 |
g/cm2 |
1.0 |
2.83 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
99247 |
2278 |
| SD |
left ventricle end-systolic wall stress |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
175 days
| 10 |
|
72.0 |
g/cm2 |
7.0 |
22.14 |
echocardiography |
0.0 |
sham ACF |
105 |
days |
|
99253 |
2278 |
| SD |
left ventricle end-systolic wall stress |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
175 days
| 10 |
|
80.0 |
g/cm2 |
6.0 |
18.97 |
echocardiography |
0.0 |
ACF |
105 |
days |
|
99254 |
2278 |
| SD |
heart left ventricle fractional shortening |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
|
38.0 |
% |
2.0 |
5.66 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
99256 |
2278 |
| SD |
heart left ventricle end-diastolic diameter |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
|
8.2 |
mm |
0.2 |
0.45 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
99340 |
2278 |
| SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
lvedd/pw |
5.7 |
null |
0.3 |
0.85 |
echocardiography |
0.0 |
ACF |
28 |
days |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
99360 |
2278 |
| SD |
heart left ventricle fractional shortening |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
|
39.0 |
% |
1.0 |
2.83 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
99369 |
2278 |
| SD |
heart left ventricle fractional shortening |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
|
43.0 |
% |
1.0 |
2.83 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
99370 |
2278 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle weight |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
84 days
| 6 |
|
1.32 |
g |
0.04 |
0.1 |
echocardiography |
0.0 |
|
0 |
|
|
99811 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart rate |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
84 days
| 7 |
|
382.0 |
beats/min |
45.0 |
119.06 |
echocardiography |
0.0 |
|
0 |
|
|
99816 |
2319 |
| SS.ZUC-Leprfa+/+/Slc |
E wave deceleration time |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
blood flow trait |
male |
91 days
| 8 |
|
33.89 |
ms |
1.4 |
3.96 |
echocardiography |
0.0 |
|
0 |
|
|
101817 |
2641 |
| SD |
left ventricle end-diastolic wall stress |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 7 |
|
4.0 |
g/cm2 |
1.0 |
2.65 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
99391 |
2278 |
| SD |
left ventricle end-systolic wall stress |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
50.0 |
g/cm2 |
3.0 |
6.71 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
lves-ws |
99395 |
2278 |
| SD |
left ventricle end-diastolic wall stress |
sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 7 |
|
4.0 |
g/cm2 |
1.0 |
2.65 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
99393 |
2278 |
| WKY |
heart rate |
left anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) then ramipril (1 mg/kg/d) (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart pumping trait |
male |
266 days-280 days |
32 |
|
373.0 |
beats/min |
15.0 |
84.85 |
echocardiography |
0.0 |
lad occlusion |
210 |
days |
|
100314 |
2460 |
| WKY |
heart ventricle septal wall thickness |
sham surgical control condition (for 196 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle wall thickness |
male |
238 days-252 days |
12 |
|
0.14 |
cm |
0.01 |
0.03 |
echocardiography |
0.0 |
lad occlusion sham |
196 |
days |
|
100336 |
2460 |
| WKY |
heart left ventricle end-diastolic diameter |
sham surgical control condition (for 196 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-diastolic diameter |
male |
238 days-252 days |
12 |
|
8.3 |
mm |
0.2 |
0.69 |
echocardiography |
0.0 |
lad occlusion sham |
196 |
days |
|
100339 |
2460 |
| WKY |
heart posterior wall thickness |
left anterior descending coronary artery occlusion (for 196 days) then furosemide (10 ml/kg/d) (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle posterior wall thickness |
male |
238 days-252 days |
20 |
|
0.17 |
cm |
0.01 |
0.04 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
|
100346 |
2460 |
| WKY |
heart posterior wall thickness |
left anterior descending coronary artery occlusion (for 196 days) then vehicle control condition (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle posterior wall thickness |
male |
238 days-252 days |
30 |
|
0.18 |
cm |
0.0 |
0.02 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
|
100347 |
2460 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle fractional shortening |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle end-diastolic diameter |
male |
91 days
| 7 |
|
44.43 |
% |
1.71 |
4.52 |
echocardiography |
0.0 |
|
0 |
|
|
101807 |
2641 |
| SS.ZUC-Leprfa+/+/Slc |
ejection fraction |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
cardiac output trait |
male |
91 days
| 8 |
|
69.1 |
% |
2.22 |
6.28 |
echocardiography |
0.0 |
|
0 |
|
|
101809 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
E wave deceleration time |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
blood flow trait |
male |
91 days
| 7 |
|
43.45 |
ms |
1.23 |
3.25 |
echocardiography |
0.0 |
|
0 |
|
|
101819 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
time constant of left ventricular pressure decay |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricular blood pressure trait |
male |
91 days
| 7 |
|
36.72 |
ms |
1.45 |
3.84 |
echocardiography |
0.0 |
|
0 |
|
|
101827 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
time constant of left ventricular pressure decay |
vehicle control condition (0.5 %) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricular blood pressure trait |
male |
91 days
| 13 |
|
33.52 |
ms |
1.09 |
3.93 |
echocardiography |
0.0 |
|
0 |
|
|
102019 |
2644 |
| SS.ZUC-Leprfa-/-/Slc |
ejection fraction |
atorvastatin (20 mg/kg/d) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
cardiac output trait |
male |
91 days
| 13 |
|
79.88 |
% |
1.51 |
5.44 |
echocardiography |
0.0 |
|
0 |
|
|
102012 |
2644 |
| SS.ZUC-Leprfa-/-/Slc |
ejection fraction |
atorvastatin (6 mg/kg/d) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
cardiac output trait |
male |
91 days
| 13 |
|
79.33 |
% |
1.21 |
4.36 |
echocardiography |
0.0 |
|
0 |
|
|
102011 |
2644 |
| SD-Myh7bem1Blar+/+ |
heart left ventricle end-diastolic internal diameter |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart left ventricle end-diastolic diameter |
not specified |
84 days
| 0 |
|
4.98 |
mm |
0.43 |
|
echocardiography |
0.0 |
|
0 |
|
SD-Myh7bem1Blar+/+ (RS:0005005) |
110948 |
3192 |
| SD-Myh7bem1Blar+/- |
heart left ventricle end-diastolic posterior wall thickness |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart left ventricle posterior wall thickness |
not specified |
84 days
| 0 |
|
2.78 |
mm |
0.43 |
|
echocardiography |
0.0 |
|
0 |
|
|
110961 |
3192 |
| SD-Myh7bem1Blar-/- |
heart left ventricle end-systolic posterior wall thickness |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart left ventricle posterior wall thickness |
not specified |
84 days
| 0 |
|
4.08 |
mm |
0.48 |
|
echocardiography |
0.0 |
|
0 |
|
heart left ventricle end-systolic internal diameter (CMO:0003851) |
110965 |
3192 |
| SD-Myh7bem1Blar+/- |
ejection fraction |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
cardiac output trait |
not specified |
84 days
| 0 |
|
98.37 |
% |
2.12 |
|
echocardiography |
0.0 |
|
0 |
|
|
110842 |
3192 |
| SD-Myh7bem1Blar+/+ |
heart interventricular end-diastolic septal wall thickness |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart ventricle septum thickness |
not specified |
84 days
| 0 |
|
1.91 |
mm |
0.31 |
|
echocardiography |
0.0 |
|
0 |
|
|
110954 |
3192 |
| SS.SHR-(D9Mco72-D9Mco105)/Mco |
heart left ventricle relative wall thickness |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) |
Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. |
heart left ventricle wall thickness |
not specified |
0 days
| 7 |
|
62.0 |
% |
3.0 |
7.94 |
echocardiography |
0.0 |
|
0 |
|
|
69609 |
749 |
| WKY |
heart left ventricle fractional shortening |
left anterior descending coronary artery occlusion (for 196 days) then vehicle control condition (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-diastolic diameter |
male |
238 days-252 days |
30 |
|
15.8 |
% |
0.7 |
3.83 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
|
100350 |
2460 |
| SS.ZUC-Leprfa+/+/Slc |
E/A wave ratio |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
blood flow trait |
male |
91 days
| 8 |
- |
1.95 |
null |
0.09 |
0.25 |
echocardiography |
0.0 |
|
0 |
|
e/a |
101813 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
E wave deceleration time |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
blood flow trait |
male |
91 days
| 12 |
|
35.82 |
ms |
0.68 |
2.36 |
echocardiography |
0.0 |
|
0 |
|
|
101820 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle fractional shortening |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle end-diastolic diameter |
male |
91 days
| 12 |
|
38.55 |
% |
1.09 |
3.78 |
echocardiography |
0.0 |
|
0 |
|
|
101808 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
E wave deceleration time |
vehicle control condition (0.5 %) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
blood flow trait |
male |
91 days
| 13 |
|
53.05 |
ms |
1.48 |
5.34 |
echocardiography |
0.0 |
|
0 |
|
|
102013 |
2644 |
| SS.ZUC-Leprfa-/-/Slc |
heart isovolumetric relaxation time |
atorvastatin (20 mg/kg/d) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart muscle relaxation trait |
male |
91 days
| 13 |
|
29.2 |
ms |
1.79 |
6.45 |
echocardiography |
0.0 |
|
0 |
|
|
102018 |
2644 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-systolic diameter |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
heart left ventricle end-systolic diameter |
female |
252 days
| 4 |
|
3.66 |
mm |
0.15 |
0.3 |
echocardiography |
0.0 |
|
0 |
|
|
101649 |
2621 |
| WKY |
ejection fraction |
left anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
cardiac output trait |
male |
266 days-280 days |
16 |
|
38.5 |
% |
3.2 |
12.8 |
echocardiography |
0.0 |
lad occlusion |
210 |
days |
|
100301 |
2460 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic diameter |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
168 days
| 6 |
|
4.54 |
mm |
0.91 |
2.23 |
echocardiography |
0.0 |
|
0 |
|
|
99789 |
2319 |
| SS.ZUC-Leprfa-/-/Slc |
myocardial performance index |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart pumping trait |
female |
91 days
| 7 |
|
0.99 |
null |
0.03 |
0.08 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101742 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
time constant of left ventricular pressure decay |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricular blood pressure trait |
female |
91 days
| 12 |
|
46.8 |
ms |
2.9 |
10.05 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101748 |
2622 |
| SD |
heart left ventricle end-diastolic diameter |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
|
7.0 |
mm |
0.1 |
0.22 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
99341 |
2278 |
| SD |
heart left ventricle end-systolic diameter |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
98 days
| 8 |
|
6.8 |
mm |
0.3 |
0.85 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
99352 |
2278 |
| SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
lvedd/pw |
4.6 |
null |
0.2 |
0.45 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
99355 |
2278 |
| SD |
left ventricle end-diastolic wall stress |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
15.0 |
g/cm2 |
2.0 |
5.66 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
99392 |
2278 |
| SD |
left ventricle end-diastolic wall stress |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
16.0 |
g/cm2 |
2.0 |
5.66 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
99394 |
2278 |
| SD |
left ventricle end-systolic wall stress |
sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 7 |
|
68.0 |
g/cm2 |
8.0 |
21.17 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
99401 |
2278 |
| WKY |
heart left ventricle end-diastolic diameter |
left anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) then ramipril (1 mg/kg/d) (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-diastolic diameter |
male |
266 days-280 days |
32 |
|
10.6 |
mm |
0.3 |
1.7 |
echocardiography |
0.0 |
lad occlusion |
210 |
days |
|
100308 |
2460 |
| WKY |
heart posterior wall thickness |
sham surgical control condition (for 196 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle posterior wall thickness |
male |
238 days-252 days |
12 |
|
0.17 |
cm |
0.01 |
0.03 |
echocardiography |
0.0 |
lad occlusion sham |
196 |
days |
|
100345 |
2460 |
| SS.SHR-(D9Mco72-D9Mco105)/Mco |
heart left ventricle end-diastolic area |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) |
Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. |
heart left ventricle size trait |
not specified |
0 days
| 7 |
|
0.88 |
cm2 |
0.06 |
0.16 |
echocardiography |
0.0 |
|
0 |
|
|
69597 |
749 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
heart ventricle septum thickness |
female |
252 days
| 5 |
|
3.11 |
mm |
0.08 |
0.18 |
echocardiography |
0.0 |
|
0 |
|
|
101648 |
2621 |
| SS-Nppbem2Mcwi+/+ |
heart rate |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
28 days
| 5 |
|
382.0 |
beats/min |
16.0 |
35.78 |
echocardiography |
0.0 |
|
0 |
|
|
99553 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart rate |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
84 days
| 6 |
|
368.0 |
beats/min |
13.0 |
31.84 |
echocardiography |
0.0 |
|
0 |
|
|
99557 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart interventricular end-systolic septal wall thickness |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
168 days
| 5 |
|
1.84 |
mm |
0.09 |
0.2 |
echocardiography |
0.0 |
|
0 |
|
|
99569 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-diastolic diameter |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
168 days
| 5 |
|
8.48 |
mm |
0.08 |
0.18 |
echocardiography |
0.0 |
|
0 |
|
|
99579 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic posterior wall thickness |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
84 days
| 10 |
|
2.03 |
mm |
0.06 |
0.19 |
echocardiography |
0.0 |
|
0 |
|
|
99588 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart interventricular end-systolic septal wall thickness |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
168 days
| 5 |
|
3.26 |
mm |
0.08 |
0.18 |
echocardiography |
0.0 |
|
0 |
|
|
99599 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic diameter |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
56 days
| 6 |
|
4.23 |
mm |
0.65 |
1.59 |
echocardiography |
0.0 |
|
0 |
|
|
99606 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic diameter |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-systolic diameter |
male |
168 days
| 5 |
|
5.0 |
mm |
0.13 |
0.29 |
echocardiography |
0.0 |
|
0 |
|
|
99610 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic posterior wall thickness |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
252 days
| 5 |
|
2.88 |
mm |
0.25 |
0.56 |
echocardiography |
0.0 |
|
0 |
|
|
99622 |
2319 |
| SS-Nppbem2Mcwi+/+ |
ejection fraction |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
168 days
| 5 |
|
85.0 |
% |
1.0 |
2.24 |
echocardiography |
0.0 |
|
0 |
|
|
99629 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle fractional shortening |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
28 days
| 7 |
|
54.9 |
% |
6.9 |
18.26 |
echocardiography |
0.0 |
|
0 |
|
|
99634 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-diastolic posterior wall thickness |
controlled sodium content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
98 days
| 4 |
|
1.58 |
mm |
0.12 |
0.24 |
echocardiography |
0.0 |
|
0 |
|
|
99714 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-diastolic septal wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
84 days
| 7 |
|
2.01 |
mm |
0.08 |
0.21 |
echocardiography |
0.0 |
|
0 |
|
|
99762 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-diastolic septal wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
168 days
| 7 |
|
1.92 |
mm |
0.12 |
0.32 |
echocardiography |
0.0 |
|
0 |
|
|
99764 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic posterior wall thickness |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
168 days
| 6 |
|
1.88 |
mm |
0.14 |
0.34 |
echocardiography |
0.0 |
|
0 |
|
|
99777 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
84 days
| 7 |
|
3.19 |
mm |
0.2 |
0.53 |
echocardiography |
0.0 |
|
0 |
|
|
99780 |
2319 |
| SS.ZUC-Leprfa+/+/Slc |
heart ventricle septal wall thickness |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle wall thickness |
male |
91 days
| 8 |
|
0.16 |
cm |
0.01 |
0.01 |
echocardiography |
0.0 |
|
0 |
|
|
101783 |
2641 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle end-diastolic diameter |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle end-diastolic diameter |
male |
91 days
| 10 |
|
7.65 |
mm |
0.12 |
0.38 |
echocardiography |
0.0 |
|
0 |
|
|
101788 |
2641 |
| SS.ZUC-Leprfa+/+/Slc |
calculated heart left ventricle weight |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle mass |
male |
91 days
| 10 |
|
962.28 |
mg |
30.76 |
97.27 |
echocardiography |
0.0 |
|
0 |
|
|
101796 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
calculated heart left ventricle weight |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle mass |
male |
91 days
| 7 |
|
1286.0 |
mg |
64.26 |
170.02 |
echocardiography |
0.0 |
|
0 |
|
|
101797 |
2641 |
| SS.ZUC-Leprfa+/+/Slc |
heart ventricle septal wall thickness |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle wall thickness |
female |
91 days
| 9 |
|
0.16 |
cm |
0.0 |
0.01 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101707 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
heart ventricle septal wall thickness |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle wall thickness |
female |
91 days
| 8 |
|
0.21 |
cm |
0.0 |
0.01 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101709 |
2622 |
| SS-Nppbem2Mcwi+/+ |
ejection fraction |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
cardiac output trait |
female |
252 days
| 4 |
|
87.0 |
% |
1.8 |
3.6 |
echocardiography |
0.0 |
|
0 |
|
|
101653 |
2621 |
| GK/CskCrljCrl |
heart rate |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
323.0 |
beats/min |
23.85 |
47.69 |
echocardiography |
0.0 |
|
0 |
|
|
103094 |
2786 |
| GK/CskCrljCrl |
heart left ventricle end-diastolic posterior wall index |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart left ventricle posterior wall thickness |
male |
168 days
| 4 |
|
4.94 |
mm/kg |
0.5 |
1.0 |
echocardiography |
0.0 |
|
0 |
|
|
103106 |
2786 |
| Crl:WI |
heart left ventricle end-systolic diameter to body weight ratio |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart left ventricle end-systolic diameter |
male |
168 days
| 4 |
|
8.68 |
mm/kg |
0.72 |
1.44 |
echocardiography |
0.0 |
|
0 |
|
|
103111 |
2786 |
| SS-Nppbem2Mcwi+/+ |
ejection fraction |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
252 days
| 6 |
|
74.8 |
% |
2.7 |
6.61 |
echocardiography |
0.0 |
|
0 |
|
|
99631 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle fractional shortening |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
168 days
| 5 |
|
46.8 |
% |
1.2 |
2.68 |
echocardiography |
0.0 |
|
0 |
|
|
99639 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle fractional shortening |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
84 days
| 10 |
|
47.3 |
% |
4.1 |
12.97 |
echocardiography |
0.0 |
|
0 |
|
|
99638 |
2319 |
| Crl:WI |
heart left ventricle end-diastolic diameter to body weight ratio |
control condition |
Korkmaz-Ic�z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. |
heart left ventricle diameter |
male |
112 days
| 10 |
|
12.55 |
mm/kg |
0.25 |
0.79 |
echocardiography |
0.0 |
|
0 |
|
|
102995 |
2783 |
| SS-Nppbem2Mcwi+/+ |
heart interventricular end-systolic septal wall thickness |
controlled sodium content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
98 days
| 4 |
|
2.91 |
mm |
0.13 |
0.26 |
echocardiography |
0.0 |
|
0 |
|
IVSs |
99716 |
2319 |
| SS-Nppbem2Mcwi+/+ |
ejection fraction |
controlled sodium chloride content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
98 days
| 4 |
|
77.3 |
% |
3.09 |
6.18 |
echocardiography |
0.0 |
|
0 |
|
|
99722 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle fractional shortening |
controlled sodium content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 4 |
|
41.7 |
% |
2.62 |
5.24 |
echocardiography |
0.0 |
|
0 |
|
|
99724 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic diameter |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
84 days
| 7 |
|
7.52 |
mm |
0.32 |
0.85 |
echocardiography |
0.0 |
|
0 |
|
|
99768 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic posterior wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
168 days
| 7 |
|
3.17 |
mm |
0.17 |
0.45 |
echocardiography |
0.0 |
|
0 |
|
|
99794 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic posterior wall thickness |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
168 days
| 6 |
|
3.23 |
mm |
0.43 |
1.05 |
echocardiography |
0.0 |
|
0 |
|
|
99795 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic posterior wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
252 days
| 7 |
|
3.41 |
mm |
0.5 |
1.32 |
echocardiography |
0.0 |
|
0 |
|
|
99796 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic posterior wall thickness |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
252 days
| 6 |
|
3.13 |
mm |
0.43 |
1.05 |
echocardiography |
0.0 |
|
0 |
|
|
99797 |
2319 |
| SS-Nppbem2Mcwi-/- |
ejection fraction |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
252 days
| 7 |
|
77.4 |
% |
6.0 |
15.87 |
echocardiography |
0.0 |
|
0 |
|
|
99802 |
2319 |
| SS-Nppbem2Mcwi-/- |
ejection fraction |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
168 days
| 6 |
|
81.0 |
% |
7.1 |
17.39 |
echocardiography |
0.0 |
|
0 |
|
|
99801 |
2319 |
| SS-Nppbem2Mcwi-/- |
ejection fraction |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
168 days
| 7 |
|
80.2 |
% |
3.4 |
9.0 |
echocardiography |
0.0 |
|
0 |
|
|
99800 |
2319 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle posterior wall thickness |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle posterior wall thickness |
female |
91 days
| 9 |
|
1.5 |
mm |
0.02 |
0.06 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101711 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle posterior wall thickness |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle posterior wall thickness |
female |
91 days
| 8 |
|
2.06 |
mm |
0.04 |
0.11 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101713 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle end-diastolic diameter |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle end-diastolic diameter |
female |
91 days
| 9 |
|
7.21 |
mm |
0.21 |
0.63 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101715 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
calculated heart left ventricle weight |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle mass |
female |
91 days
| 9 |
|
764.0 |
mg |
27.0 |
81.0 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101723 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
E wave deceleration time |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart pumping trait |
female |
91 days
| 8 |
|
56.9 |
ms |
1.8 |
5.09 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101733 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
myocardial performance index |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart pumping trait |
female |
91 days
| 8 |
|
0.61 |
null |
0.03 |
0.08 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101741 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricular end-diastolic blood pressure to heart left ventricular end-diastolic diameter ratio |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricular blood pressure trait |
female |
91 days
| 8 |
|
0.63 |
mmHg/mm |
0.05 |
0.14 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101753 |
2622 |
| SD |
heart left ventricle end-diastolic diameter |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
|
10.1 |
mm |
0.3 |
0.85 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
99236 |
2278 |
| SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
175 days
| 10 |
lvedd/pw |
7.9 |
null |
0.4 |
1.26 |
echocardiography |
0.0 |
ACF |
105 |
days |
heart left ventricle end-diastolic dimeter to posterior wall thickness ratio |
99246 |
2278 |
| SD |
left ventricle end-diastolic wall stress |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
14.0 |
g/cm2 |
3.0 |
8.49 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
99248 |
2278 |
| SD |
heart left ventricle end-systolic diameter |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
72 days
| 5 |
|
4.3 |
mm |
0.5 |
1.12 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
99348 |
2278 |
| SD |
heart left ventricle end-diastolic diameter |
sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 7 |
|
7.6 |
mm |
0.1 |
0.26 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
99345 |
2278 |
| SD |
heart left ventricle end-systolic diameter |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
98 days
| 7 |
|
4.7 |
mm |
0.2 |
0.53 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
99351 |
2278 |
| SD |
heart left ventricle end-systolic diameter |
sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
98 days
| 7 |
|
4.7 |
mm |
0.2 |
0.53 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
99353 |
2278 |
| SD |
heart left ventricle fractional shortening |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 7 |
|
38.0 |
% |
2.0 |
5.29 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
99367 |
2278 |
| SD |
ejection fraction |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
cardiac output trait |
male |
72 days
| 5 |
|
76.0 |
% |
5.0 |
11.18 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
99372 |
2278 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle weight |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
84 days
| 7 |
|
1.53 |
g |
0.08 |
0.21 |
echocardiography |
0.0 |
|
0 |
|
|
99810 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle weight |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
168 days
| 6 |
|
1.59 |
g |
0.05 |
0.12 |
echocardiography |
0.0 |
|
0 |
|
|
99813 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart rate |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
84 days
| 6 |
|
361.0 |
beats/min |
11.0 |
26.94 |
echocardiography |
0.0 |
|
0 |
|
|
99817 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart rate |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
168 days
| 7 |
|
349.0 |
beats/min |
20.0 |
52.92 |
echocardiography |
0.0 |
|
0 |
|
|
99818 |
2319 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle relative wall thickness |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle wall thickness |
male |
91 days
| 8 |
|
39.0 |
% |
2.0 |
5.66 |
echocardiography |
0.0 |
|
0 |
|
|
101801 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricular end-diastolic blood pressure to heart left ventricular end-diastolic diameter ratio |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricular blood pressure trait |
male |
91 days
| 3 |
|
1.08 |
mmHg/mm |
0.11 |
0.19 |
echocardiography |
0.0 |
|
0 |
|
lvedp/lvdd |
101831 |
2641 |
| SD |
left ventricle end-systolic wall stress |
artificial aortocaval fistula (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
54.0 |
g/cm2 |
3.0 |
6.71 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
99396 |
2278 |
| SD |
left ventricle end-diastolic wall stress |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
16.0 |
g/cm2 |
4.0 |
8.94 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
99390 |
2278 |
| SD |
left ventricle end-systolic wall stress |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
72 days
| 5 |
|
37.0 |
g/cm2 |
7.0 |
15.65 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
99398 |
2278 |
| WKY |
heart left ventricle end-systolic diameter |
left anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-systolic diameter |
male |
266 days-280 days |
16 |
|
9.1 |
mm |
0.4 |
1.6 |
echocardiography |
0.0 |
lad occlusion |
210 |
days |
|
100310 |
2460 |
| WKY |
E/A wave ratio |
left anterior descending coronary artery occlusion (for 196 days) then furosemide (10 ml/kg/d) (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
blood flow trait |
male |
238 days-252 days |
20 |
|
1.61 |
null |
0.21 |
0.94 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
|
100355 |
2460 |
| SS.ZUC-Leprfa+/+/Slc |
heart isovolumetric relaxation time |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart muscle relaxation trait |
male |
91 days
| 8 |
|
24.22 |
ms |
2.42 |
6.84 |
echocardiography |
0.0 |
|
0 |
|
|
101821 |
2641 |
| SS.ZUC-Leprfa+/+/Slc |
time constant of left ventricular pressure decay |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricular blood pressure trait |
male |
91 days
| 8 |
|
27.47 |
ms |
0.82 |
2.32 |
echocardiography |
0.0 |
|
0 |
|
|
101825 |
2641 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricular end-diastolic blood pressure to heart left ventricular end-diastolic diameter ratio |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricular blood pressure trait |
male |
91 days
| 4 |
|
0.56 |
mmHg/mm |
0.04 |
0.08 |
echocardiography |
0.0 |
|
0 |
|
lvedp/lvdd |
101829 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
E wave deceleration time |
atorvastatin (6 mg/kg/d) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
blood flow trait |
male |
91 days
| 13 |
|
46.93 |
ms |
1.06 |
3.82 |
echocardiography |
0.0 |
|
0 |
|
|
102014 |
2644 |
| SD-Myh7bem1Blar+/- |
heart interventricular end-systolic septal wall thickness |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart ventricle septum thickness |
not specified |
84 days
| 0 |
|
4.11 |
mm |
0.49 |
|
echocardiography |
0.0 |
|
0 |
|
|
110958 |
3192 |
| SD-Myh7bem1Blar+/+ |
ejection fraction |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
cardiac output trait |
not specified |
84 days
| 0 |
|
92.12 |
% |
8.24 |
|
echocardiography |
0.0 |
|
0 |
|
SD-Myh7bem1Blar+/+ (RS:0005005) |
110840 |
3192 |
| SD-Myh7bem1Blar-/- |
heart interventricular end-systolic septal wall thickness |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart ventricle septum thickness |
not specified |
84 days
| 0 |
|
3.89 |
mm |
0.73 |
|
echocardiography |
0.0 |
|
0 |
|
heart left ventricle end-systolic internal diameter (CMO:0003851) |
110959 |
3192 |
| SS/Jr |
heart left ventricle relative wall thickness |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) |
Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. |
heart left ventricle wall thickness |
not specified |
0 days
| 6 |
|
107.0 |
% |
34.0 |
83.28 |
echocardiography |
0.0 |
|
0 |
|
|
69611 |
749 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle fractional shortening |
atorvastatin (6 mg/kg/d) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle end-diastolic diameter |
male |
91 days
| 13 |
|
43.53 |
% |
1.18 |
4.25 |
echocardiography |
0.0 |
|
0 |
|
|
102008 |
2644 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic posterior wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
252 days
| 7 |
|
2.17 |
mm |
1.94 |
5.13 |
echocardiography |
0.0 |
|
0 |
|
|
99778 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
168 days
| 7 |
|
3.24 |
mm |
0.21 |
0.56 |
echocardiography |
0.0 |
|
0 |
|
|
99782 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart rate |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
heart pumping trait |
female |
252 days
| 5 |
|
355.0 |
beats/min |
10.0 |
22.36 |
echocardiography |
0.0 |
|
0 |
|
|
101660 |
2621 |
| SS.ZUC-Leprfa-/-/Slc |
heart ventricle septal wall thickness |
atorvastatin (6 mg/kg/d) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle wall thickness |
male |
91 days
| 13 |
|
0.2 |
cm |
0.0 |
0.01 |
echocardiography |
0.0 |
|
0 |
|
|
101993 |
2644 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle fractional shortening |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
28 days
| 5 |
|
46.0 |
% |
8.4 |
18.78 |
echocardiography |
0.0 |
|
0 |
|
|
99633 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle fractional shortening |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
252 days
| 6 |
|
39.0 |
% |
2.2 |
5.39 |
echocardiography |
0.0 |
|
0 |
|
|
99641 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle fractional shortening |
controlled sodium content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 4 |
|
47.0 |
% |
1.41 |
2.82 |
echocardiography |
0.0 |
|
0 |
|
|
99725 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic diameter |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
252 days
| 6 |
|
8.52 |
mm |
0.51 |
1.25 |
echocardiography |
0.0 |
|
0 |
|
|
99773 |
2319 |
| Crl:WI |
left ventricular ejection time |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
61.51 |
ms |
2.21 |
4.42 |
echocardiography |
0.0 |
|
0 |
|
|
103135 |
2786 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricular end-diastolic blood pressure to heart left ventricular end-diastolic diameter ratio |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricular blood pressure trait |
female |
91 days
| 9 |
|
0.32 |
mmHg/mm |
0.02 |
0.06 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101751 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricular end-diastolic blood pressure to heart left ventricular end-diastolic diameter ratio |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricular blood pressure trait |
male |
91 days
| 5 |
|
0.6 |
mmHg/mm |
0.05 |
0.11 |
echocardiography |
0.0 |
|
0 |
|
lvedp/lvdd |
101830 |
2641 |
| WKY |
heart left ventricle end-diastolic diameter |
sham surgical control condition (for 224 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-diastolic diameter |
male |
266 days-280 days |
5 |
|
7.9 |
mm |
0.2 |
0.45 |
echocardiography |
0.0 |
lad occlusion sham |
210 |
days |
|
100306 |
2460 |
| WKY |
heart left ventricle end-diastolic diameter |
left anterior descending coronary artery occlusion (for 196 days) then vehicle control condition (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-diastolic diameter |
male |
238 days-252 days |
30 |
|
10.6 |
mm |
0.1 |
0.55 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
|
100341 |
2460 |
| SS.SHR-(D9Mco72-D9Mco105)/Mco |
heart left ventricle posterior wall thickness |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) |
Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. |
heart left ventricle posterior wall thickness |
not specified |
0 days
| 7 |
|
2.4 |
mm |
0.1 |
0.26 |
echocardiography |
0.0 |
|
0 |
|
|
69605 |
749 |
| SS-Nppbem2Mcwi+/+ |
heart interventricular end-systolic septal wall thickness |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
heart ventricle septum thickness |
female |
252 days
| 4 |
|
3.51 |
mm |
0.07 |
0.14 |
echocardiography |
0.0 |
|
0 |
|
IVSs |
101647 |
2621 |
| SS-Nppbem2Mcwi+/+ |
heart rate |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
168 days
| 5 |
|
337.0 |
beats/min |
13.0 |
29.07 |
echocardiography |
0.0 |
|
0 |
|
|
99559 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
28 days
| 7 |
|
0.81 |
mm |
0.1 |
0.26 |
echocardiography |
0.0 |
|
0 |
|
|
99564 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart interventricular end-systolic septal wall thickness |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
84 days
| 6 |
|
1.7 |
mm |
0.1 |
0.24 |
echocardiography |
0.0 |
|
0 |
|
|
99567 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
56 days
| 6 |
|
1.21 |
mm |
0.12 |
0.29 |
echocardiography |
0.0 |
|
0 |
|
|
99566 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart interventricular end-systolic septal wall thickness |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
252 days
| 6 |
|
2.41 |
mm |
0.14 |
0.34 |
echocardiography |
0.0 |
|
0 |
|
|
99571 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic diameter |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
56 days
| 6 |
|
8.18 |
mm |
0.35 |
0.86 |
echocardiography |
0.0 |
|
0 |
|
|
99576 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic diameter |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
84 days
| 10 |
|
7.52 |
mm |
0.32 |
1.01 |
echocardiography |
0.0 |
|
0 |
|
|
99578 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-diastolic posterior wall thickness |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
56 days
| 5 |
|
1.28 |
mm |
0.17 |
0.38 |
echocardiography |
0.0 |
|
0 |
|
|
99585 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-diastolic posterior wall thickness |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
28 days
| 5 |
|
0.9 |
mm |
0.05 |
0.11 |
echocardiography |
0.0 |
|
0 |
|
|
99583 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-diastolic posterior wall thickness |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
168 days
| 5 |
|
2.02 |
mm |
0.08 |
0.18 |
echocardiography |
0.0 |
|
0 |
|
|
99589 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
56 days
| 6 |
|
2.53 |
mm |
0.24 |
0.59 |
echocardiography |
0.0 |
|
0 |
|
|
99596 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
84 days
| 10 |
|
3.19 |
mm |
0.2 |
0.63 |
echocardiography |
0.0 |
|
0 |
|
|
99598 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
252 days
| 5 |
|
3.58 |
mm |
0.12 |
0.27 |
echocardiography |
0.0 |
|
0 |
|
|
99602 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic posterior wall thickness |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
28 days
| 7 |
|
1.48 |
mm |
0.19 |
0.5 |
echocardiography |
0.0 |
|
0 |
|
|
99614 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-systolic posterior wall thickness |
control condition (for 56 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle posterior wall thickness |
male |
56 days
| 5 |
|
2.35 |
mm |
0.39 |
0.87 |
echocardiography |
0.0 |
|
0 |
|
|
99615 |
2319 |
| SS-Nppbem2Mcwi-/- |
ejection fraction |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
28 days
| 7 |
|
90.3 |
% |
4.3 |
11.38 |
echocardiography |
0.0 |
|
0 |
|
|
99624 |
2319 |
| SS-Nppbem2Mcwi+/+ |
ejection fraction |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
84 days
| 6 |
|
83.3 |
% |
2.0 |
4.9 |
echocardiography |
0.0 |
|
0 |
|
|
99627 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle weight |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
168 days
| 5 |
|
1.64 |
g |
0.02 |
0.04 |
echocardiography |
0.0 |
|
0 |
|
|
99674 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle weight |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
28 days
| 7 |
|
0.75 |
g |
0.05 |
0.13 |
echocardiography |
0.0 |
|
0 |
|
|
99669 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle weight |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
252 days
| 6 |
|
1.94 |
g |
0.06 |
0.15 |
echocardiography |
0.0 |
|
0 |
|
|
99676 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle weight |
control condition (for 252 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
252 days
| 5 |
|
1.84 |
g |
0.03 |
0.07 |
echocardiography |
0.0 |
|
0 |
|
|
99677 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart interventricular end-diastolic septal wall thickness |
controlled sodium content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
98 days
| 4 |
|
1.67 |
mm |
0.09 |
0.18 |
echocardiography |
0.0 |
|
0 |
|
|
99710 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart interventricular end-systolic septal wall thickness |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart ventricle septum thickness |
male |
252 days
| 7 |
|
3.48 |
mm |
0.26 |
0.69 |
echocardiography |
0.0 |
|
0 |
|
|
99784 |
2319 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle end-diastolic diameter |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle end-diastolic diameter |
male |
91 days
| 12 |
|
8.05 |
mm |
0.07 |
0.24 |
echocardiography |
0.0 |
|
0 |
|
|
101790 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle end-diastolic diameter |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle end-diastolic diameter |
male |
91 days
| 7 |
|
7.58 |
mm |
0.2 |
0.53 |
echocardiography |
0.0 |
|
0 |
|
|
101789 |
2641 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle posterior wall thickness |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle posterior wall thickness |
male |
91 days
| 10 |
|
1.7 |
mm |
0.06 |
0.19 |
echocardiography |
0.0 |
|
0 |
|
|
101792 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle posterior wall thickness |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricle posterior wall thickness |
male |
91 days
| 7 |
|
2.16 |
mm |
0.09 |
0.24 |
echocardiography |
0.0 |
|
0 |
|
|
101793 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
heart ventricle septal wall thickness |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle wall thickness |
female |
91 days
| 7 |
|
0.21 |
cm |
0.01 |
0.01 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101710 |
2622 |
| SS-Nppbem2Mcwi-/- |
ejection fraction |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
cardiac output trait |
male |
252 days
| 6 |
|
74.5 |
% |
6.4 |
15.68 |
echocardiography |
0.0 |
|
0 |
|
|
99803 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle fractional shortening |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
heart left ventricle end-diastolic diameter |
female |
252 days
| 4 |
|
49.5 |
% |
2.2 |
4.4 |
echocardiography |
0.0 |
|
0 |
|
|
101655 |
2621 |
| SS.ZUC-Leprfa-/-/Slc |
heart ventricle septal wall thickness |
vehicle control condition (0.5 %) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle wall thickness |
male |
91 days
| 13 |
|
0.21 |
cm |
0.0 |
0.01 |
echocardiography |
0.0 |
|
0 |
|
|
101992 |
2644 |
| Crl:WI |
heart left ventricle end-diastolic diameter to body weight ratio |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart left ventricle end-diastolic diameter |
male |
168 days
| 4 |
|
15.32 |
mm/kg |
1.01 |
2.03 |
echocardiography |
0.0 |
|
0 |
|
|
103109 |
2786 |
| GK/CskCrljCrl |
heart left ventricle end-diastolic diameter to body weight ratio |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart left ventricle end-diastolic diameter |
male |
168 days
| 4 |
|
21.91 |
mm/kg |
1.06 |
2.11 |
echocardiography |
0.0 |
|
0 |
|
|
103110 |
2786 |
| Crl:WI |
heart left ventricle weight to body weight ratio |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart left ventricle mass |
male |
168 days
| 4 |
|
2.45 |
mg/g |
0.16 |
0.31 |
echocardiography |
0.0 |
|
0 |
|
|
103113 |
2786 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle fractional shortening |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
168 days
| 5 |
|
43.4 |
% |
1.5 |
3.35 |
echocardiography |
0.0 |
|
0 |
|
|
99640 |
2319 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle weight |
control condition (for 28 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
28 days
| 5 |
|
0.79 |
g |
0.01 |
0.02 |
echocardiography |
0.0 |
|
0 |
|
|
99643 |
2319 |
| Crl:WI |
heart left ventricle end-diastolic posterior wall index |
control condition |
Korkmaz-Ic�z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. |
heart left ventricle posterior wall thickness |
male |
112 days
| 10 |
|
6.04 |
mm/kg |
0.27 |
0.85 |
echocardiography |
0.0 |
|
0 |
|
|
102991 |
2783 |
| SS-Nppbem2Mcwi+/+ |
heart rate |
controlled sodium chloride content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
98 days
| 4 |
|
420.0 |
beats/min |
7.0 |
14.0 |
echocardiography |
0.0 |
|
0 |
|
|
99728 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic diameter |
gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
84 days
| 6 |
|
8.33 |
mm |
0.4 |
0.98 |
echocardiography |
0.0 |
|
0 |
|
|
99769 |
2319 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-diastolic diameter |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
252 days
| 7 |
|
7.99 |
mm |
0.62 |
1.64 |
echocardiography |
0.0 |
|
0 |
|
|
99772 |
2319 |
| Crl:WI |
heart left ventricle fractional shortening |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart left ventricle end-diastolic diameter |
male |
168 days
| 4 |
|
43.45 |
% |
1.78 |
3.56 |
echocardiography |
0.0 |
|
0 |
|
|
103119 |
2786 |
| GK/CskCrljCrl |
heart ventricle end-systolic septal wall index |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart ventricle septum thickness |
male |
168 days
| 4 |
|
7.66 |
mm/kg |
0.63 |
1.26 |
echocardiography |
0.0 |
|
0 |
|
|
103118 |
2786 |
| Crl:WI |
A wave velocity |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
813.67 |
mm/s |
76.65 |
153.3 |
echocardiography |
0.0 |
|
0 |
|
a wave |
103123 |
2786 |
| Crl:WI |
A' wave velocity |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
51.35 |
mm/s |
6.4 |
12.8 |
echocardiography |
0.0 |
|
0 |
|
a' wave |
103129 |
2786 |
| GK/CskCrljCrl |
left ventricular ejection time |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
65.54 |
ms |
3.12 |
6.23 |
echocardiography |
0.0 |
|
0 |
|
|
103136 |
2786 |
| Crl:WI |
myocardial performance index |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
0.49 |
null |
0.03 |
0.05 |
echocardiography |
0.0 |
|
0 |
|
|
103139 |
2786 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle end-diastolic diameter |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle end-diastolic diameter |
female |
91 days
| 12 |
|
6.5 |
mm |
0.17 |
0.59 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101716 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle fractional shortening |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle end-diastolic diameter |
female |
91 days
| 12 |
|
55.2 |
% |
1.9 |
6.58 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101720 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle fractional shortening |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle end-diastolic diameter |
female |
91 days
| 8 |
|
47.7 |
% |
1.9 |
5.37 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101721 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricle relative wall thickness |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle wall thickness |
female |
91 days
| 12 |
|
45.0 |
% |
1.0 |
3.46 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101728 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle relative wall thickness |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle wall thickness |
female |
91 days
| 7 |
|
61.0 |
% |
2.0 |
5.29 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101730 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle relative wall thickness |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle wall thickness |
female |
91 days
| 8 |
|
57.0 |
% |
2.0 |
5.66 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101729 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
calculated heart left ventricle weight |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricle mass |
female |
91 days
| 7 |
|
1176.0 |
mg |
46.0 |
121.7 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101726 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
E wave deceleration time |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart pumping trait |
female |
91 days
| 7 |
|
59.9 |
ms |
1.0 |
2.65 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101734 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
heart isovolumetric relaxation time |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart muscle relaxation trait |
female |
91 days
| 12 |
|
39.0 |
ms |
1.0 |
3.46 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101736 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
time constant of left ventricular pressure decay |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricular blood pressure trait |
female |
91 days
| 9 |
|
36.2 |
ms |
0.5 |
1.5 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101747 |
2622 |
| SS.ZUC-Leprfa+/+/Slc |
heart left ventricular end-diastolic blood pressure to heart left ventricular end-diastolic diameter ratio |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart left ventricular blood pressure trait |
female |
91 days
| 12 |
|
0.63 |
mmHg/mm |
0.05 |
0.17 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101752 |
2622 |
| SD |
heart left ventricle end-diastolic diameter |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
175 days
| 10 |
|
11.6 |
mm |
0.4 |
1.26 |
echocardiography |
0.0 |
ACF |
105 |
days |
|
99238 |
2278 |
| SD |
heart left ventricle fractional shortening |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
|
38.0 |
% |
4.0 |
11.31 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
99255 |
2278 |
| SD |
heart left ventricle fractional shortening |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
175 days
| 10 |
|
40.0 |
% |
1.0 |
3.16 |
echocardiography |
0.0 |
sham ACF |
105 |
days |
|
99257 |
2278 |
| SD |
heart left ventricle end-diastolic diameter |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 8 |
|
10.2 |
mm |
0.2 |
0.57 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
99346 |
2278 |
| SD |
heart left ventricle end-systolic diameter |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
72 days
| 5 |
|
4.0 |
mm |
0.2 |
0.45 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
99350 |
2278 |
| SD |
heart left ventricle end-systolic diameter |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
98 days
| 8 |
|
5.9 |
mm |
0.2 |
0.57 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
99354 |
2278 |
| SD |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
98 days
| 7 |
lvedd/pw |
4.2 |
null |
0.2 |
0.53 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
heart left ventricle end-diastolic diameter to posterior wall thickness ratio |
99359 |
2278 |
| SD |
heart left ventricle fractional shortening |
artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
|
50.0 |
% |
3.0 |
6.71 |
echocardiography |
0.0 |
ACF |
2 |
days |
|
99366 |
2278 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle weight |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle mass |
male |
252 days
| 7 |
|
1.78 |
g |
0.04 |
0.11 |
echocardiography |
0.0 |
|
0 |
|
|
99814 |
2319 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricular end-diastolic blood pressure to heart left ventricular end-diastolic diameter ratio |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricular blood pressure trait |
male |
91 days
| 9 |
|
0.65 |
mmHg/mm |
0.05 |
0.15 |
echocardiography |
0.0 |
|
0 |
|
lvedp/lvdd |
101832 |
2641 |
| SD |
ejection fraction |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
cardiac output trait |
male |
98 days
| 7 |
|
66.0 |
% |
2.0 |
5.29 |
echocardiography |
0.0 |
sham ACF |
28 |
days |
|
99375 |
2278 |
| SD |
ejection fraction |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
cardiac output trait |
male |
98 days
| 8 |
|
63.0 |
% |
2.0 |
5.66 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
99376 |
2278 |
| SD |
ejection fraction |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
cardiac output trait |
male |
98 days
| 8 |
|
71.0 |
% |
1.0 |
2.83 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
99378 |
2278 |
| SD |
left ventricle end-systolic wall stress |
artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricular blood pressure trait |
male |
98 days
| 8 |
|
62.0 |
g/cm2 |
6.0 |
16.97 |
echocardiography |
0.0 |
ACF |
28 |
days |
|
99402 |
2278 |
| WKY |
heart left ventricle fractional shortening |
left anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-diastolic diameter |
male |
266 days-280 days |
16 |
|
16.8 |
% |
1.6 |
6.4 |
echocardiography |
0.0 |
lad occlusion |
210 |
days |
|
100304 |
2460 |
| WKY |
heart left ventricle fractional shortening |
left anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) then ramipril (1 mg/kg/d) (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle end-diastolic diameter |
male |
266 days-280 days |
32 |
|
18.0 |
% |
1.5 |
8.49 |
echocardiography |
0.0 |
lad occlusion |
210 |
days |
|
100305 |
2460 |
| WKY |
heart ventricle septal wall thickness |
left anterior descending coronary artery occlusion (for 196 days) then furosemide (10 ml/kg/d) (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
heart left ventricle wall thickness |
male |
238 days-252 days |
20 |
|
0.13 |
cm |
0.03 |
0.13 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
|
100337 |
2460 |
| SS.ZUC-Leprfa-/-/Slc |
ejection fraction |
control condition |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
cardiac output trait |
male |
91 days
| 7 |
|
82.46 |
% |
1.65 |
4.37 |
echocardiography |
0.0 |
|
0 |
|
|
101811 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
ejection fraction |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
cardiac output trait |
male |
91 days
| 12 |
|
76.47 |
% |
1.2 |
4.16 |
echocardiography |
0.0 |
|
0 |
|
|
101812 |
2641 |
| SS.ZUC-Leprfa+/+/Slc |
ejection fraction |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
cardiac output trait |
male |
91 days
| 10 |
|
72.2 |
% |
2.34 |
7.4 |
echocardiography |
0.0 |
|
0 |
|
|
101810 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
E/A wave ratio |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
blood flow trait |
male |
91 days
| 12 |
|
1.91 |
null |
0.07 |
0.24 |
echocardiography |
0.0 |
|
0 |
|
e/a |
101816 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle end-diastolic diameter |
atorvastatin (20 mg/kg/d) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle end-diastolic diameter |
male |
91 days
| 13 |
|
8.43 |
mm |
0.11 |
0.4 |
echocardiography |
0.0 |
|
0 |
|
|
101997 |
2644 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle relative wall thickness |
vehicle control condition (0.5 %) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle wall thickness |
male |
91 days
| 13 |
|
49.0 |
% |
1.0 |
3.61 |
echocardiography |
0.0 |
|
0 |
|
|
102004 |
2644 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle relative wall thickness |
atorvastatin (6 mg/kg/d) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle wall thickness |
male |
91 days
| 13 |
|
46.0 |
% |
1.0 |
3.61 |
echocardiography |
0.0 |
|
0 |
|
|
102005 |
2644 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle fractional shortening |
vehicle control condition (0.5 %) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle end-diastolic diameter |
male |
91 days
| 13 |
|
47.66 |
% |
2.43 |
8.76 |
echocardiography |
0.0 |
|
0 |
|
|
102007 |
2644 |
| SS.ZUC-Leprfa-/-/Slc |
heart left ventricle relative wall thickness |
atorvastatin (20 mg/kg/d) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricle wall thickness |
male |
91 days
| 13 |
|
47.0 |
% |
2.0 |
7.21 |
echocardiography |
0.0 |
|
0 |
|
|
102006 |
2644 |
| SS.ZUC-Leprfa-/-/Slc |
heart isovolumetric relaxation time |
atorvastatin (6 mg/kg/d) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart muscle relaxation trait |
male |
91 days
| 13 |
|
32.78 |
ms |
1.14 |
4.11 |
echocardiography |
0.0 |
|
0 |
|
|
102017 |
2644 |
| SS.ZUC-Leprfa-/-/Slc |
time constant of left ventricular pressure decay |
atorvastatin (6 mg/kg/d) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricular blood pressure trait |
male |
91 days
| 13 |
|
25.89 |
ms |
1.53 |
5.52 |
echocardiography |
0.0 |
|
0 |
|
|
102020 |
2644 |
| SD-Myh7bem1Blar+/- |
heart left ventricle end-diastolic internal diameter |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart left ventricle end-diastolic diameter |
not specified |
84 days
| 0 |
|
3.34 |
mm |
0.88 |
|
echocardiography |
0.0 |
|
0 |
|
|
110949 |
3192 |
| SD-Myh7bem1Blar-/- |
heart left ventricle end-diastolic posterior wall thickness |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart left ventricle posterior wall thickness |
not specified |
84 days
| 0 |
|
3.2 |
mm |
0.5 |
|
echocardiography |
0.0 |
|
0 |
|
heart left ventricle end-systolic internal diameter (CMO:0003851) |
110962 |
3192 |
| SD-Myh7bem1Blar-/- |
heart left ventricle end-diastolic internal diameter |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart left ventricle end-diastolic diameter |
not specified |
84 days
| 0 |
|
3.19 |
mm |
0.93 |
|
echocardiography |
0.0 |
|
0 |
|
|
110950 |
3192 |
| SD-Myh7bem1Blar-/- |
heart left ventricle end-systolic internal diameter |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart left ventricle end-systolic diameter |
not specified |
84 days
| 0 |
|
0.69 |
mm |
0.44 |
|
echocardiography |
0.0 |
|
0 |
|
heart left ventricle end-systolic internal diameter (CMO:0003851) |
110953 |
3192 |
| SD-Myh7bem1Blar+/- |
heart interventricular end-diastolic septal wall thickness |
control condition |
Chen P, etal., Sci China Life Sci. 2020 Sep;63(9):1347-1362. doi: 10.1007/s11427-019-1627-y. Epub 2020 Mar 17. |
heart ventricle septum thickness |
not specified |
84 days
| 0 |
|
2.52 |
mm |
0.39 |
|
echocardiography |
0.0 |
|
0 |
|
|
110955 |
3192 |
| WKY |
E/A wave ratio |
left anterior descending coronary artery occlusion (for 196 days) then vehicle control condition (for 182 days) |
Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. |
blood flow trait |
male |
238 days-252 days |
30 |
|
1.85 |
null |
0.14 |
0.77 |
echocardiography |
0.0 |
lad occlusion |
196 |
days |
|
100356 |
2460 |
| SS.ZUC-Leprfa+/+/Slc |
time constant of left ventricular pressure decay |
everolimus (0.83 mg/kg/d) (for 28 days) |
Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. |
heart left ventricular blood pressure trait |
male |
91 days
| 10 |
|
29.01 |
ms |
2.59 |
8.19 |
echocardiography |
0.0 |
|
0 |
|
|
101826 |
2641 |
| SS.ZUC-Leprfa-/-/Slc |
time constant of left ventricular pressure decay |
atorvastatin (20 mg/kg/d) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
heart left ventricular blood pressure trait |
male |
91 days
| 13 |
|
22.53 |
ms |
0.89 |
3.21 |
echocardiography |
0.0 |
|
0 |
|
|
102021 |
2644 |
| SS.ZUC-Leprfa-/-/Slc |
E wave deceleration time |
atorvastatin (20 mg/kg/d) (for 28 days) |
Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. |
blood flow trait |
male |
91 days
| 13 |
|
43.5 |
ms |
1.57 |
5.66 |
echocardiography |
0.0 |
|
0 |
|
|
102015 |
2644 |
| SS-Nppbem2Mcwi+/+ |
heart left ventricle end-diastolic diameter |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
heart left ventricle end-diastolic diameter |
female |
252 days
| 4 |
|
7.28 |
mm |
0.11 |
0.22 |
echocardiography |
0.0 |
|
0 |
|
|
101643 |
2621 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle end-systolic posterior wall thickness |
control condition (for 252 days) |
Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. |
heart left ventricle posterior wall thickness |
female |
252 days
| 5 |
|
3.1 |
mm |
0.16 |
0.36 |
echocardiography |
0.0 |
|
0 |
|
|
101652 |
2621 |
| SS-Nppbem2Mcwi-/- |
heart left ventricle fractional shortening |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart left ventricle end-diastolic diameter |
male |
84 days
| 7 |
|
47.3 |
% |
4.1 |
10.85 |
echocardiography |
0.0 |
|
0 |
|
|
99804 |
2319 |
| Crl:WI |
heart left ventricle end-systolic posterior wall index |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart left ventricle posterior wall thickness |
male |
168 days
| 4 |
|
5.96 |
mm/kg |
0.36 |
0.72 |
echocardiography |
0.0 |
|
0 |
|
|
103107 |
2786 |
| SS-Nppbem2Mcwi-/- |
heart rate |
controlled sodium chloride content diet (for 21 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
98 days
| 4 |
|
421.0 |
beats/min |
4.0 |
8.0 |
echocardiography |
0.0 |
|
0 |
|
|
99729 |
2319 |
| Crl:WI |
E wave velocity |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
1041.33 |
mm/s |
82.04 |
164.08 |
echocardiography |
0.0 |
|
0 |
|
|
103121 |
2786 |
| GK/CskCrljCrl |
E/E' wave ratio |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
26.84 |
null |
3.78 |
7.55 |
echocardiography |
0.0 |
|
0 |
|
e/e' wave |
103132 |
2786 |
| GK/CskCrljCrl |
left ventricular isovolumetric relaxation time |
control condition |
Devanathan S, et al., PLoS One. 2013 Oct 21;8(10):e78477. doi: 10.1371/journal.pone.0078477. eCollection 2013. |
heart pumping trait |
male |
168 days
| 4 |
|
24.88 |
ms |
2.17 |
4.34 |
echocardiography |
0.0 |
|
0 |
|
|
103138 |
2786 |
| SS.ZUC-Leprfa+/+/Slc |
myocardial performance index |
bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
heart pumping trait |
female |
91 days
| 12 |
|
0.57 |
null |
0.03 |
0.1 |
echocardiography |
0.0 |
ovariectomy |
42 |
days |
|
101740 |
2622 |
| SD |
heart left ventricle end-systolic diameter |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-systolic diameter |
male |
72 days
| 5 |
|
4.0 |
mm |
0.2 |
0.45 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
99347 |
2278 |
| SD |
ejection fraction |
sham surgical control condition (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
cardiac output trait |
male |
72 days
| 5 |
|
66.0 |
% |
3.0 |
6.71 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
99371 |
2278 |
| SD |
heart left ventricle fractional shortening |
sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle end-diastolic diameter |
male |
72 days
| 5 |
|
43.0 |
% |
2.0 |
4.47 |
echocardiography |
0.0 |
sham ACF |
2 |
days |
|
99365 |
2278 |
| SS-Nppbem2Mcwi-/- |
heart rate |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
heart pumping trait |
male |
252 days
| 7 |
|
327.0 |
beats/min |
19.0 |
50.27 |
echocardiography |
0.0 |
|
0 |
|
|
99820 |
2319 |
