Phenominer Database Results (113 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Sample Notes Record ID Study ID
MWF-Chr 6SHR/Rkb serum creatinine level control condition Schulz A, et al., Clin Sci (Lond). 2007 Oct 22;. blood creatinine amount female 168 days 20 0.48 mg/dl 0.01 0.06 serum creatinine analysis 0.0 0 68176 309
Hsd:WI serum creatinine level 1H-pyrazole (10 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. blood creatinine amount male 0 days 6 1.11 mg/dl 0.25 0.62 serum creatinine analysis 0.0 0 75974 1544
Hsd:WI serum creatinine level lycopene (6 mg/kg/d) (for 12 days) then cisplatin (7 mg/kg) Erman F, et al., Biol Trace Elem Res. 2014 Feb 16. blood creatinine amount not specified 78 days 7 0.4 mg/dl 0.01 0.03 serum creatinine analysis 0.0 0 76043 1546
Crl:CD(SD) serum creatinine level control condition (for 28 days) then vehicle control condition (for 84 days) Jia G, et al., Pediatr Nephrol. 2010 Jun;25(6):1139-46. Epub 2010 Mar 13. blood creatinine amount male 112 days 5 0.43 mg/dl 0.03 0.07 serum creatinine analysis 0.0 0 100766 2521
SD serum creatinine level controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then paricalcitol (0.8 mg/kg) (for 90 days) Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. blood creatinine amount female 0 days 10 1.5 mg/dl 0.11 0.35 serum creatinine analysis 0.0 unx 97 days 100639 2499
SHR/NCrlCrlj serum creatinine level unilateral nephrectomy (for 42 days) then controlled candesartan content drinking water (1 mg/kg/d) (for 28 days) Kohara K, et al., Hypertension. 1993 Jun;21(6 Pt 2):975-9. blood creatinine amount male 126 days 8 0.67 mg/dl 0.04 0.11 serum creatinine analysis 0.0 unx 42 days 101247 2583
SS.ZUC-Leprfa-/-/Slc serum creatinine level fasting (for 16 hours) Hattori T, et al., Nutr Diabetes. 2011 Jan 31;1:e1. doi: 10.1038/nutd.2010.1. blood creatinine amount male 126 days 7 1.09 mg/dl 0.19 0.5 serum creatinine analysis 0.0 0 101934 2642
SD serum creatinine level control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. blood creatinine amount male 120 days 3 0.55 mg/dl 0.01 0.01 serum creatinine analysis 0.0 0 100206 2439
SS.ZUC-Leprfa+/+/Slc serum creatinine level everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. blood creatinine amount male 91 days 10 0.34 mg/dl 0.01 0.03 serum creatinine analysis 0.0 0 101874 2641
LOU/M serum creatinine level control condition van Hoesel QG, etal., J Natl Cancer Inst. 1986 Feb;76(2):299-307. blood creatinine amount female 84 days 43 0.43 mg/dl 0.01 0.03 serum creatinine analysis 0.0 0 109291 3144
SD serum creatinine level control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. blood creatinine amount male 60 days 3 0.53 mg/dl 0.02 0.04 serum creatinine analysis 0.0 0 100204 2439
MWF/Fub serum creatinine level control condition Schulz A, et al., J Am Soc Nephrol 2003 Dec;14(12):3081-9. blood creatinine amount male 126 days 8 0.58 mg/dl 0.07 0.2 serum creatinine analysis 0 13006 325
MWF-Chr 6SHR/Rkb serum creatinine level control condition Schulz A, et al., J Am Soc Nephrol. 2007 Jan;18(1):113-21 blood creatinine amount not specified 168 days 19 0.43 mg/dl 0.02 0.08 serum creatinine analysis 0.0 0 65374 117
MWF/FubRkb serum creatinine level control condition Schulz A, et al., J Am Soc Nephrol 2002 Nov;13(11):2706-14. blood creatinine amount not specified 0 days 8 0.49 mg/dl 0.0 0.01 serum creatinine analysis 0.0 0 67605 769
SS-Renem1Mcwi+/+ serum creatinine level controlled sodium content diet (0.4 %) (for 42 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. blood creatinine amount male 63 days 5 0.22 mg/dl 0.03 0.07 serum creatinine analysis 0.0 0 98343 2038
Hsd:WI serum creatinine level cisplatin (7 mg/kg) Erman F, et al., Biol Trace Elem Res. 2014 Feb 16. blood creatinine amount not specified 78 days 7 1.37 mg/dl 0.21 0.56 serum creatinine analysis 0.0 0 76040 1546
LEW/Rkb serum creatinine level control condition Schulz A, et al., J Am Soc Nephrol 2002 Nov;13(11):2706-14. blood creatinine amount not specified 0 days 8 0.42 mg/dl 0.0 0.0 serum creatinine analysis 0.0 0 67606 769
SS/NEisSlc serum creatinine level controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) then vehicle control condition (for 49 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. blood creatinine amount male 126 days 8 0.47 mg/dl 0.04 0.11 serum creatinine analysis 0.0 0 102326 2684
SS/NEisSlc serum creatinine level controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) then tolvaptan (0.05 %) (for 49 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. blood creatinine amount male 126 days 8 0.35 mg/dl 0.01 0.03 serum creatinine analysis 0.0 0 102327 2684
SR/NEisSlc creatinine clearance controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. glomerular filtration trait male 126 days 8 3.9 ml/min 0.8 2.26 serum creatinine analysis 0.0 0 102331 2684
MWF serum creatinine level lisinopril (80-100 mg/l) Macconi D, et al., Am J Pathol. 2009 Mar;174(3):797-807. Epub 2009 Jan 22. blood creatinine amount male 280 days 10 0.77 mg/dl 0.06 0.19 serum creatinine analysis 0.0 0 100245 2459
SD creatinine clearance controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then paricalcitol (0.8 mg/kg) (for 90 days) Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. glomerular filtration trait female 0 days 10 0.35 ml/min 0.02 0.06 serum creatinine analysis 0.0 unx 97 days 100644 2499
PCK-Pkhd1pck/CrljCrl serum creatinine level control condition (for 28 days) then vehicle control condition (for 84 days) Jia G, et al., Pediatr Nephrol. 2010 Jun;25(6):1139-46. Epub 2010 Mar 13. blood creatinine amount male 112 days 5 0.51 mg/dl 0.04 0.09 serum creatinine analysis 0.0 0 100765 2521
FHH/EurMcwi creatinine clearance to total kidney weight ratio control condition Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. glomerular filtration trait male 56 days 6 1.2 ml/min/g 0.07 0.17 serum creatinine analysis 0.0 0 99489 2318
SHR/NCrlCrlj serum creatinine level unilateral nephrectomy (for 42 days) then controlled delapril content drinking water (30 mg/kg/d) (for 28 days) Kohara K, et al., Hypertension. 1993 Jun;21(6 Pt 2):975-9. blood creatinine amount male 126 days 9 0.74 mg/dl 0.04 0.12 serum creatinine analysis 0.0 unx 42 days 101248 2583
WI creatinine clearance to body weight ratio controlled in utero environment (for 21 days) and standard diet (50 % of calories) (for 21 days) Ceravolo GS, et al., Life Sci. 2007 Jan 30;80(8):782-7. Epub 2006 Nov 10. glomerular filtration trait male 102 days 6 0.48 ml/min/100g 0.08 0.18 serum creatinine analysis 0.0 0 101066 2563
SS.ZUC-Leprfa+/+/Slc creatinine clearance to body weight ratio control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. glomerular filtration trait male 91 days 8 0.43 ml/min/100g 0.03 0.08 serum creatinine analysis 0.0 0 101877 2641
SS.ZUC-Leprfa-/-/Slc creatinine clearance to total kidney weight ratio everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. glomerular filtration trait male 91 days 12 0.28 ml/min/g 0.04 0.14 serum creatinine analysis 0.0 0 101884 2641
SS-Renem1Mcwi+/+ serum creatinine level controlled sodium content diet (0.4 %) (for 42 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. blood creatinine amount male 63 days 8 0.53 mg/dl 0.02 0.06 serum creatinine analysis 0.0 0 98345 2038
LOU/M serum creatinine level doxorubicin (1 mg/kg) (for 49 days) van Hoesel QG, etal., J Natl Cancer Inst. 1986 Feb;76(2):299-307. blood creatinine amount female 133 days 43 0.61 mg/dl 0.0 0.03 serum creatinine analysis 0.0 XCO:0000539 49 days intravenous 109293 3144
MWF/Ztm serum creatinine level control condition Remuzzi A, etal., Kidney Int. 2006 Apr;69(7):1124-30. doi: 10.1038/sj.ki.5000060. blood creatinine amount male 350 days 9 1.22 mg/dl 0.05 0.15 serum creatinine analysis 0.0 0 109951 3158
MWF/Fub serum creatinine level control condition Kreutz R, etal., J Hypertens. 2007 Nov;25(11):2308-16. doi: 10.1097/HJH.0b013e3282ef8611. blood creatinine amount male 112 days 8 0.63 mg/dl 0.02 0.06 serum creatinine analysis 0.0 0 109864 3156
SHR/FubRkb serum creatinine level control condition Schulz A, etal., Physiol Genomics. 2008 Sep 17;35(1):30-5. Epub 2008 Jul 22. blood creatinine amount male 168 days 10 0.4 mg/dl 0.01 0.04 serum creatinine analysis 0.0 0 108946 3133
MWF/FubRkb serum creatinine level control condition Schulz A, etal., Physiol Genomics. 2008 Sep 17;35(1):30-5. Epub 2008 Jul 22. blood creatinine amount female 168 days 10 0.47 mg/dl 0.01 0.04 serum creatinine analysis 0.0 0 108951 3133
MWF-Chr 8SHR/Rkb creatinine clearance control condition Schulz A, etal., Physiol Genomics. 2008 Sep 17;35(1):30-5. Epub 2008 Jul 22. glomerular filtration trait male 168 days 10 0.0 ml/min 0.0 0.0 serum creatinine analysis 0.0 0 108954 3133
MWF/FubRkb creatinine clearance control condition Schulz A, etal., Physiol Genomics. 2008 Sep 17;35(1):30-5. Epub 2008 Jul 22. glomerular filtration trait female 168 days 10 0.0 ml/min 0.0 0.0 serum creatinine analysis 0.0 0 108957 3133
WKY serum creatinine level control condition Macconi D, etal., J Am Soc Nephrol. 2012 Sep;23(9):1496-505. doi: 10.1681/ASN.2011121144. Epub 2012 Jul 19. blood creatinine amount male 350 days 4 0.34 mg/dl 0.02 0.04 serum creatinine analysis 0.0 0 109547 3147
WKY serum creatinine level control condition Macconi D, etal., J Am Soc Nephrol. 2012 Sep;23(9):1496-505. doi: 10.1681/ASN.2011121144. Epub 2012 Jul 19. blood creatinine amount male 420 days 4 0.32 mg/dl 0.04 0.07 serum creatinine analysis 0.0 0 109548 3147
PCK-Pkhd1pck/CrljCrl serum creatinine level control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. blood creatinine amount male 180 days 4 0.58 mg/dl 0.14 0.24 serum creatinine analysis 0.0 0 100207 2439
SHR/Fub serum creatinine level control condition Schulz A, et al., J Am Soc Nephrol 2003 Dec;14(12):3081-9. blood creatinine amount male 126 days 8 0.77 mg/dl 0.16 0.44 serum creatinine analysis 0 13012 325
SS-Renem1Mcwi+/+ serum creatinine level controlled sodium content diet (0.4 %) (for 42 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. blood creatinine amount female 63 days 8 0.27 mg/dl 0.03 0.08 serum creatinine analysis 0.0 0 98346 2038
SS-Renem1Mcwi+/+ serum creatinine level controlled sodium content diet (0.4 %) (for 42 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. blood creatinine amount female 63 days 4 0.43 mg/dl 0.03 0.06 serum creatinine analysis 0.0 0 98348 2038
SHR/FubRkb serum creatinine level control condition Schulz A, et al., J Am Soc Nephrol. 2007 Jan;18(1):113-21 blood creatinine amount not specified 168 days 10 0.4 mg/dl 0.01 0.04 serum creatinine analysis 0.0 0 65373 117
MWF/FubRkb serum creatinine level control condition Schulz A, et al., J Am Soc Nephrol. 2007 Jan;18(1):113-21 blood creatinine amount not specified 168 days 18 0.42 mg/dl 0.01 0.05 serum creatinine analysis 0.0 0 65375 117
SD creatinine clearance left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (80 mg/kg) Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. glomerular filtration trait male 0 days 7 0.44 ml/min 0.11 0.29 serum creatinine analysis 0.0 unx 70 days 98994 2179
FHH-Nr4a1m1Mcwi creatinine clearance to total kidney weight ratio control condition Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. glomerular filtration trait male 168 days 6 0.6 ml/min/g 0.2 0.49 serum creatinine analysis 0.0 0 99494 2318
WKY serum creatinine level control condition (for 280 days) Macconi D, et al., Am J Pathol. 2009 Mar;174(3):797-807. Epub 2009 Jan 22. blood creatinine amount male 280 days 9 0.53 mg/dl 0.03 0.1 serum creatinine analysis 0.0 0 100246 2459
MWF serum creatinine level lisinopril (80-100 mg/l) (for 140 days) Macconi D, et al., Am J Pathol. 2009 Mar;174(3):797-807. Epub 2009 Jan 22. blood creatinine amount male 420 days 10 0.91 mg/dl 0.02 0.06 serum creatinine analysis 0.0 0 100250 2459
SD serum creatinine level controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then vehicle control condition (100 ul) (for 90 days) Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. blood creatinine amount female 0 days 13 1.65 mg/dl 0.14 0.5 serum creatinine analysis 0.0 unx 97 days 100637 2499
SD serum creatinine level controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then paricalcitol (0.8 mg/kg) (for 90 days) and enalapril (25 mg/l) (for 90 days) Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. blood creatinine amount female 0 days 12 0.93 mg/dl 0.05 0.17 serum creatinine analysis 0.0 unx 97 days 100640 2499
SD creatinine clearance control condition Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. glomerular filtration trait female 0 days 8 0.96 ml/min 0.07 0.2 serum creatinine analysis 0.0 - 0 days 100641 2499
SHR/NCrlCrlj serum creatinine level unilateral nephrectomy (for 42 days) Kohara K, et al., Hypertension. 1993 Jun;21(6 Pt 2):975-9. blood creatinine amount male 126 days 5 0.95 mg/dl 0.08 0.18 serum creatinine analysis 0.0 unx 42 days 101246 2583
SHR/NCrlCrlj serum creatinine level unilateral nephrectomy (for 42 days) then controlled hydralazine content drinking water (15 mg/kg/d) (for 28 days) Kohara K, et al., Hypertension. 1993 Jun;21(6 Pt 2):975-9. blood creatinine amount male 126 days 5 0.92 mg/dl 0.06 0.13 serum creatinine analysis 0.0 unx 42 days 101249 2583
SS-Nppbem2Mcwi+/+ serum creatinine level control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. blood creatinine amount male 252 days 6 0.3 mg/dl 0.1 0.24 serum creatinine analysis 0.0 0 99750 2319
WI creatinine clearance to body weight ratio controlled in utero environment (for 21 days) and standard diet (100 % of calories) (for 21 days) Ceravolo GS, et al., Life Sci. 2007 Jan 30;80(8):782-7. Epub 2006 Nov 10. glomerular filtration trait male 102 days 6 0.54 ml/min/100g 0.06 0.13 serum creatinine analysis 0.0 0 101065 2563
MWF/Ztm serum creatinine level control condition Macconi D, etal., J Am Soc Nephrol. 2012 Sep;23(9):1496-505. doi: 10.1681/ASN.2011121144. Epub 2012 Jul 19. blood creatinine amount male 350 days 7 0.77 mg/dl 0.11 0.3 serum creatinine analysis 0.0 0 109541 3147
MWF/Ztm serum creatinine level controlled lisinopril content drinking water (80 mg/l) (for 1 days) Macconi D, etal., J Am Soc Nephrol. 2012 Sep;23(9):1496-505. doi: 10.1681/ASN.2011121144. Epub 2012 Jul 19. blood creatinine amount male 280 days 8 0.57 mg/dl 0.04 0.12 serum creatinine analysis 0.0 0 109543 3147
MWF/Ztm serum creatinine level controlled lisinopril content drinking water (80 mg/l) (for 140 days) Macconi D, etal., J Am Soc Nephrol. 2012 Sep;23(9):1496-505. doi: 10.1681/ASN.2011121144. Epub 2012 Jul 19. blood creatinine amount male 420 days 8 0.61 mg/dl 0.03 0.08 serum creatinine analysis 0.0 0 109545 3147
MWF/FubRkb serum creatinine level control condition Schulz A, et al., Clin Sci (Lond). 2007 Oct 22;. blood creatinine amount female 168 days 18 0.47 mg/dl 0.0 0.02 serum creatinine analysis 0.0 0 68177 309
SS.ZUC-Leprfa-/-/Slc serum creatinine level control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. blood creatinine amount male 91 days 7 0.34 mg/dl 0.04 0.11 serum creatinine analysis 0.0 0 101875 2641
SS.ZUC-Leprfa-/-/Slc creatinine clearance to total kidney weight ratio control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. glomerular filtration trait male 91 days 7 0.4 ml/min/g 0.03 0.08 serum creatinine analysis 0.0 0 101883 2641
FHH-Nr4a1m1Mcwi creatinine clearance to total kidney weight ratio control condition Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. glomerular filtration trait male 56 days 6 1.0 ml/min/g 0.12 0.29 serum creatinine analysis 0.0 0 99490 2318
FHH/EurMcwi creatinine clearance to total kidney weight ratio control condition Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. glomerular filtration trait male 168 days 6 1.2 ml/min/g 0.2 0.49 serum creatinine analysis 0.0 0 99493 2318
SR/NEisSlc serum creatinine level controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. blood creatinine amount male 126 days 8 0.22 mg/dl 0.01 0.03 serum creatinine analysis 0.0 0 102325 2684
MWF serum creatinine level control condition (for 280 days) Macconi D, et al., Am J Pathol. 2009 Mar;174(3):797-807. Epub 2009 Jan 22. blood creatinine amount male 280 days 10 0.76 mg/dl 0.06 0.2 serum creatinine analysis 0.0 0 100244 2459
MWF serum creatinine level control condition (for 350 days) Macconi D, et al., Am J Pathol. 2009 Mar;174(3):797-807. Epub 2009 Jan 22. blood creatinine amount male 350 days 10 0.97 mg/dl 0.09 0.27 serum creatinine analysis 0.0 0 100247 2459
MWF serum creatinine level control condition (for 420 days) Macconi D, et al., Am J Pathol. 2009 Mar;174(3):797-807. Epub 2009 Jan 22. blood creatinine amount male 402 days-420 days 10 1.77 mg/dl 0.24 0.77 serum creatinine analysis 0.0 0 Ages originally entered as low bound 420 days and high bound 402 days. 100249 2459
SD creatinine clearance controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then vehicle control condition (100 ul) (for 90 days) Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. glomerular filtration trait female 0 days 13 0.3 ml/min 0.03 0.11 serum creatinine analysis 0.0 unx 97 days 100642 2499
SD creatinine clearance controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then paricalcitol (0.8 mg/kg) (for 90 days) and enalapril (25 mg/l) (for 90 days) Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. glomerular filtration trait female 0 days 12 0.58 ml/min 0.05 0.17 serum creatinine analysis 0.0 unx 97 days 100645 2499
SS-Nppbem2Mcwi-/- serum creatinine level control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. blood creatinine amount male 252 days 6 0.4 mg/dl 0.1 0.24 serum creatinine analysis 0.0 0 99751 2319
SD creatinine clearance left nephrectomy (for 70 days) Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. glomerular filtration trait male 0 days 5 1.4 ml/min 0.2 0.45 serum creatinine analysis 0.0 unx 70 days 103797 2179
SS.ZUC-Leprfa+/+/Slc serum creatinine level control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. blood creatinine amount male 91 days 8 0.35 mg/dl 0.01 0.03 serum creatinine analysis 0.0 0 101873 2641
SS.ZUC-Leprfa+/+/Slc creatinine clearance to total kidney weight ratio control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. glomerular filtration trait male 91 days 8 0.48 ml/min/g 0.02 0.06 serum creatinine analysis 0.0 0 101881 2641
SS.ZUC-Leprfa+/+/Slc serum creatinine level fasting (for 16 hours) Hattori T, et al., Nutr Diabetes. 2011 Jan 31;1:e1. doi: 10.1038/nutd.2010.1. blood creatinine amount male 126 days 6 0.32 mg/dl 0.03 0.07 serum creatinine analysis 0.0 0 101933 2642
SD serum creatinine level control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. blood creatinine amount male 180 days 5 0.55 mg/dl 0.06 0.1 serum creatinine analysis 0.0 0 100208 2439
Crl:WI serum creatinine level control condition Kreutz R, etal., J Hypertens. 2007 Nov;25(11):2308-16. doi: 10.1097/HJH.0b013e3282ef8611. blood creatinine amount male 112 days 8 0.58 mg/dl 0.03 0.08 serum creatinine analysis 0.0 0 109863 3156
WKY serum creatinine level control condition Macconi D, etal., J Am Soc Nephrol. 2012 Sep;23(9):1496-505. doi: 10.1681/ASN.2011121144. Epub 2012 Jul 19. blood creatinine amount male 280 days 4 0.33 mg/dl 0.03 0.06 serum creatinine analysis 0.0 0 109546 3147
MWF-Chr 8SHR/Rkb serum creatinine level control condition Schulz A, etal., Physiol Genomics. 2008 Sep 17;35(1):30-5. Epub 2008 Jul 22. blood creatinine amount female 168 days 10 0.48 mg/dl 0.01 0.04 serum creatinine analysis 0.0 0 108949 3133
SHR/FubRkb creatinine clearance control condition Schulz A, etal., Physiol Genomics. 2008 Sep 17;35(1):30-5. Epub 2008 Jul 22. glomerular filtration trait female 168 days 10 0.0 ml/min 0.0 0.0 serum creatinine analysis 0.0 0 108953 3133
MWF-Chr 8SHR/Rkb creatinine clearance control condition Schulz A, etal., Physiol Genomics. 2008 Sep 17;35(1):30-5. Epub 2008 Jul 22. glomerular filtration trait female 168 days 10 0.0 ml/min 0.0 0.0 serum creatinine analysis 0.0 0 108955 3133
MWF/FubRkb creatinine clearance control condition Schulz A, etal., Physiol Genomics. 2008 Sep 17;35(1):30-5. Epub 2008 Jul 22. glomerular filtration trait male 168 days 10 0.0 ml/min 0.0 0.0 serum creatinine analysis 0.0 0 108956 3133
Hsd:WI serum creatinine level silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. blood creatinine amount male 0 days 6 0.85 mg/dl 0.03 0.08 serum creatinine analysis 0.0 0 75975 1544
SD serum creatinine level controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then enalapril (25 mg/l) (for 90 days) Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. blood creatinine amount female 0 days 12 0.93 mg/dl 0.02 0.07 serum creatinine analysis 0.0 unx 97 days 100638 2499
Hsd:WI serum creatinine level control condition Erman F, et al., Biol Trace Elem Res. 2014 Feb 16. blood creatinine amount not specified 78 days 7 0.29 mg/dl 0.01 0.03 serum creatinine analysis 0.0 0 76038 1546
SHR/FubRkb serum creatinine level control condition Schulz A, et al., Clin Sci (Lond). 2007 Oct 22;. blood creatinine amount female 168 days 10 0.4 mg/dl 0.02 0.06 serum creatinine analysis 0.0 0 68175 309
Hsd:WI serum creatinine level vehicle control condition (for 10 days) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. blood creatinine amount male 0 days 6 0.54 mg/dl 0.01 0.03 serum creatinine analysis 0.0 0 75972 1544
Hsd:WI serum creatinine level lycopene (6 mg/kg/d) (for 12 days) Erman F, et al., Biol Trace Elem Res. 2014 Feb 16. blood creatinine amount not specified 78 days 7 0.33 mg/dl 0.02 0.05 serum creatinine analysis 0.0 0 76039 1546
SS/NEisSlc creatinine clearance controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) then vehicle control condition (for 49 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. glomerular filtration trait male 126 days 8 1.9 ml/min 0.5 1.41 serum creatinine analysis 0.0 0 102332 2684
SS/NEisSlc creatinine clearance controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) then tolvaptan (0.05 %) (for 49 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. glomerular filtration trait male 126 days 8 3.6 ml/min 0.7 1.98 serum creatinine analysis 0.0 0 102333 2684
FHH/EurMcwi creatinine clearance to total kidney weight ratio control condition Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. glomerular filtration trait male 112 days 6 0.9 ml/min/g 0.06 0.15 serum creatinine analysis 0.0 0 99491 2318
FHH-Nr4a1m1Mcwi creatinine clearance to total kidney weight ratio control condition Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. glomerular filtration trait male 112 days 6 0.7 ml/min/g 0.06 0.15 serum creatinine analysis 0.0 0 99492 2318
MWF serum creatinine level lisinopril (80-100 mg/l) (for 70 days) Macconi D, et al., Am J Pathol. 2009 Mar;174(3):797-807. Epub 2009 Jan 22. blood creatinine amount male 350 days 10 0.86 mg/dl 0.03 0.11 serum creatinine analysis 0.0 0 100248 2459
SD creatinine clearance controlled calcium content diet (0.6 %) (for 97 days) and controlled content diet (0.9 %) (for 97 days) and unilateral nephrectomy (for 97 days) then enalapril (25 mg/l) (for 90 days) Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. glomerular filtration trait female 0 days 12 0.56 ml/min 0.03 0.1 serum creatinine analysis 0.0 unx 97 days 100643 2499
PCK-Pkhd1pck/CrljCrl serum creatinine level control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. blood creatinine amount male 120 days 3 0.57 mg/dl 0.03 0.06 serum creatinine analysis 0.0 0 100205 2439
SS.ZUC-Leprfa-/-/Slc serum creatinine level everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. blood creatinine amount male 91 days 12 0.37 mg/dl 0.03 0.1 serum creatinine analysis 0.0 0 101876 2641
SS.ZUC-Leprfa-/-/Slc creatinine clearance to body weight ratio control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. glomerular filtration trait male 91 days 7 0.28 ml/min/100g 0.03 0.08 serum creatinine analysis 0.0 0 101879 2641
SS.ZUC-Leprfa+/+/Slc creatinine clearance to total kidney weight ratio everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. glomerular filtration trait male 91 days 10 0.47 ml/min/g 0.05 0.16 serum creatinine analysis 0.0 0 101882 2641
SS-Renem1Mcwi+/- serum creatinine level controlled sodium content diet (0.4 %) (for 42 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. blood creatinine amount male 63 days 9 0.26 mg/dl 0.02 0.06 serum creatinine analysis 0.0 0 98344 2038
SS-Renem1Mcwi+/- serum creatinine level controlled sodium content diet (0.4 %) (for 42 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. blood creatinine amount female 63 days 9 0.26 mg/dl 0.02 0.06 serum creatinine analysis 0.0 0 98347 2038
LOU/M serum creatinine level doxorubicin (1 mg/kg) (for 35 days) van Hoesel QG, etal., J Natl Cancer Inst. 1986 Feb;76(2):299-307. blood creatinine amount female 119 days 43 0.57 mg/dl 0.0 0.02 serum creatinine analysis 0.0 XCO:0000539 35 days 109292 3144
MWF/Ztm serum creatinine level control condition Remuzzi A, etal., Kidney Int. 2006 Apr;69(7):1124-30. doi: 10.1038/sj.ki.5000060. blood creatinine amount male 420 days 7 1.92 mg/dl 0.29 0.77 serum creatinine analysis 0.0 0 109952 3158
SHR/FubRkb serum creatinine level control condition Schulz A, etal., Physiol Genomics. 2008 Sep 17;35(1):30-5. Epub 2008 Jul 22. blood creatinine amount female 168 days 10 0.4 mg/dl 0.02 0.06 serum creatinine analysis 0.0 0 108947 3133
MWF-Chr 8SHR/Rkb serum creatinine level control condition Schulz A, etal., Physiol Genomics. 2008 Sep 17;35(1):30-5. Epub 2008 Jul 22. blood creatinine amount male 168 days 10 0.44 mg/dl 0.01 0.05 serum creatinine analysis 0.0 0 108948 3133
MWF/FubRkb serum creatinine level control condition Schulz A, etal., Physiol Genomics. 2008 Sep 17;35(1):30-5. Epub 2008 Jul 22. blood creatinine amount male 168 days 10 0.42 mg/dl 0.01 0.04 serum creatinine analysis 0.0 0 108950 3133
SHR/FubRkb creatinine clearance control condition Schulz A, etal., Physiol Genomics. 2008 Sep 17;35(1):30-5. Epub 2008 Jul 22. glomerular filtration trait male 168 days 10 0.0 ml/min 0.0 0.0 serum creatinine analysis 0.0 0 108952 3133
MWF/Ztm serum creatinine level control condition Macconi D, etal., J Am Soc Nephrol. 2012 Sep;23(9):1496-505. doi: 10.1681/ASN.2011121144. Epub 2012 Jul 19. blood creatinine amount male 280 days 7 0.57 mg/dl 0.05 0.12 serum creatinine analysis 0.0 0 109540 3147
MWF/Ztm serum creatinine level control condition Macconi D, etal., J Am Soc Nephrol. 2012 Sep;23(9):1496-505. doi: 10.1681/ASN.2011121144. Epub 2012 Jul 19. blood creatinine amount male 420 days 7 1.78 mg/dl 0.52 1.38 serum creatinine analysis 0.0 0 109542 3147
MWF/Ztm serum creatinine level controlled lisinopril content drinking water (80 mg/l) (for 70 days) Macconi D, etal., J Am Soc Nephrol. 2012 Sep;23(9):1496-505. doi: 10.1681/ASN.2011121144. Epub 2012 Jul 19. blood creatinine amount male 350 days 8 0.66 mg/dl 0.05 0.14 serum creatinine analysis 0.0 0 109544 3147
SS.ZUC-Leprfa+/+/Slc creatinine clearance to body weight ratio everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. glomerular filtration trait male 91 days 10 0.39 ml/min/100g 0.04 0.13 serum creatinine analysis 0.0 0 101878 2641
SS.ZUC-Leprfa-/-/Slc creatinine clearance to body weight ratio everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. glomerular filtration trait male 91 days 12 0.17 ml/min/100g 0.02 0.07 serum creatinine analysis 0.0 0 101880 2641
SD serum creatinine level control condition Finch JL, et al., Am J Physiol Renal Physiol. 2011 Sep 28. blood creatinine amount female 0 days 8 0.58 mg/dl 0.03 0.08 serum creatinine analysis 0.0 0 days 100636 2499
Hsd:WI serum creatinine level vehicle control condition (for 10 days) then cisplatin (7.5 mg/kg) Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. blood creatinine amount male 0 days 6 1.69 mg/dl 0.06 0.14 serum creatinine analysis 0.0 0 75973 1544
PCK-Pkhd1pck/CrljCrl serum creatinine level control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. blood creatinine amount male 60 days 3 0.45 mg/dl 0.05 0.09 serum creatinine analysis 0.0 0 100203 2439