RHA/N |
defecation rate |
control condition |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
defecation behavior trait |
both |
111 days-118 days |
19 |
0.74 |
/5 min |
0.07 |
0.3 |
ex vivo visual assessment |
300.0 |
|
0 |
|
video monitoring |
|
|
66024 |
114 |
BN/OlaHsd |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral nerve myelin (2 mg) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
7 |
0.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84473 |
1178 |
BN/OlaHsd |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral myelin protein 2 peptide 58-81 (100 ug) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
7 |
0.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84523 |
1178 |
WF/NHsd |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral myelin protein 2 peptide 58-81 (100 ug) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
5 |
0.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84525 |
1178 |
F344/NHsd |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral myelin protein 2 peptide 58-81 (100 ug) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
3 |
0.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84526 |
1178 |
SD |
heart left ventricle infarction area to total heart left ventricle area ratio |
left anterior descending coronary artery occlusion (for 28 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left ventricle integrity trait |
male |
77 days
| 6 |
35.4 |
% |
1.9 |
4.65 |
ex vivo visual assessment |
0.0 |
lad occlusion |
28 |
days |
|
|
|
101127 |
2564 |
WAG/RijCrl |
metastatic lung tumor number |
S4MH cells (250 X 10E3) (for 21 days) then sham surgical control condition (for 11 days) |
Garc?a-Alonso I, et al., J Surg Res. 2008 Aug;148(2):185-90. doi: 10.1016/j.jss.2007.06.026. Epub 2007 Aug 2. |
lung integrity trait |
male |
87 days
| 10 |
28.5 |
null |
7.68 |
24.29 |
ex vivo visual assessment |
0.0 |
S4MH injection |
21 |
days |
|
|
|
108162 |
3119 |
ACI/SegHsd |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral nerve myelin (2 mg) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
4 |
0.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84474 |
1178 |
N:HS |
defecation rate |
control condition |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
defecation behavior trait |
both |
111 days-118 days |
20 |
2.87 |
/5 min |
3.65 |
16.34 |
ex vivo visual assessment |
300 |
|
0 |
|
video monitoring |
|
|
66023 |
114 |
RLA/N |
defecation rate |
control condition |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
defecation behavior trait |
both |
111 days-118 days |
18 |
0.22 |
/5 min |
0.02 |
0.1 |
ex vivo visual assessment |
300 |
|
0 |
|
video monitoring |
|
|
66025 |
114 |
SHR/NIcoCrlf |
defecation rate |
control condition |
Ramos A, et al., Behav Brain Res. 1998 Nov;96(1-2):195-205 |
defecation behavior trait |
female |
56 days-63 days |
12 |
0.1 |
/5 min |
0.1 |
0.35 |
ex vivo visual assessment |
300 |
|
0 |
|
video monitoring |
defecation rate measurement |
|
65140 |
108 |
LEW.1N |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral nerve myelin (2 mg) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
6 |
100.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84521 |
1178 |
ACI/SegHsd |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral myelin protein 2 peptide 58-81 (100 ug) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
4 |
0.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84524 |
1178 |
COP |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral myelin protein 2 peptide 58-81 (100 ug) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
8 |
100.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84528 |
1178 |
COP |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral nerve myelin (2 mg) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
8 |
100.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84514 |
1178 |
LEW.1AV1/Kini |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral nerve myelin (2 mg) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
41 |
100.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84522 |
1178 |
F344/NHsd |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral nerve myelin (2 mg) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
4 |
0.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84476 |
1178 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral myelin protein 2 peptide 58-81 (100 ug) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
5 |
80.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84529 |
1178 |
PVG |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral myelin protein 2 peptide 58-81 (100 ug) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
8 |
0.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84531 |
1178 |
LEW.1AR1/Ztm |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral myelin protein 2 peptide 58-81 (100 ug) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
4 |
100.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84533 |
1178 |
LEW.1AV1/Kini |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral myelin protein 2 peptide 58-81 (100 ug) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
6 |
100.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84536 |
1178 |
ACI/SegHsd |
percentage of study population developing pituitary tumors during a period of time |
17 beta-estradiol (27.5 mg) (between 146 and 202 days) |
Shull JD, et al., Carcinogenesis. 1997 Aug;18(8):1595-601 |
pituitary gland integrity trait |
female |
207 days-265 days |
21 |
100.0 |
% |
|
|
ex vivo visual assessment |
0 |
|
0 |
|
|
|
|
65551 |
76 |
WF.DA-(D19Mit1-D19Mit6)/Kop |
post-insult time to onset of moribundity |
controlled 4-nitroquinoline N-oxide content drinking water (10 mg/l) (for 180 days) |
Hirano M, et al., Cancer Lett 2005 May 2;. |
life span trait |
both |
42 days-222 days |
23 |
179.65 |
d |
0.35 |
1.67 |
ex vivo visual assessment |
0.0 |
|
0 |
|
|
180 day maximum |
|
70328 |
1339 |
PVG.1AV1 |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral nerve myelin (2 mg) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
8 |
100.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84516 |
1178 |
LEW.1F |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral nerve myelin (2 mg) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
4 |
100.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84520 |
1178 |
LEW/Han |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral myelin protein 2 peptide 58-81 (100 ug) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
18 |
100.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84527 |
1178 |
LEW.1WR1/WorBrm |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral myelin protein 2 peptide 58-81 (100 ug) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
4 |
100.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84532 |
1178 |
LEW.1F |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral myelin protein 2 peptide 58-81 (100 ug) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
4 |
50.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84534 |
1178 |
LEW.1N |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral myelin protein 2 peptide 58-81 (100 ug) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
12 |
0.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84535 |
1178 |
SD |
heart left ventricle infarction area to total heart left ventricle area ratio |
left anterior descending coronary artery occlusion (for 140 days) |
Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. |
heart left ventricle integrity trait |
male |
189 days
| 10 |
37.9 |
% |
2.0 |
6.32 |
ex vivo visual assessment |
0.0 |
lad occlusion |
140 |
days |
|
|
|
101128 |
2564 |
LEW/NIcoCrlf |
defecation rate |
control condition |
Ramos A, et al., Behav Brain Res. 1998 Nov;96(1-2):195-205 |
defecation behavior trait |
male |
56 days-63 days |
5 |
0.6 |
/5 min |
0.6 |
1.34 |
ex vivo visual assessment |
300 |
|
0 |
|
video monitoring |
defecation rate measurement |
|
65137 |
108 |
SHR/NIcoCrlf |
defecation rate |
control condition |
Ramos A, et al., Behav Brain Res. 1998 Nov;96(1-2):195-205 |
defecation behavior trait |
male |
56 days-63 days |
12 |
0.1 |
/5 min |
0.1 |
0.35 |
ex vivo visual assessment |
300 |
|
0 |
|
video monitoring |
defecation rate measurement |
|
65138 |
108 |
DA/ZtmKini |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral nerve myelin (2 mg) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
8 |
50.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84515 |
1178 |
LEW.1WR1/WorBrm |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral nerve myelin (2 mg) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
37 |
100.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84518 |
1178 |
PVG.1AV1 |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral myelin protein 2 peptide 58-81 (100 ug) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
4 |
25.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84530 |
1178 |
LEW/Han |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral nerve myelin (2 mg) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
29 |
100.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84513 |
1178 |
WF/NHsd |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral nerve myelin (2 mg) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
5 |
0.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84475 |
1178 |
WAG/RijCrl |
metastatic lung tumor number |
S4MH cells (250 X 10E3) (for 21 days) then partial hepatectomy (for 11 days) |
Garc?a-Alonso I, et al., J Surg Res. 2008 Aug;148(2):185-90. doi: 10.1016/j.jss.2007.06.026. Epub 2007 Aug 2. |
lung integrity trait |
male |
87 days
| 10 |
99.2 |
null |
0.54 |
1.71 |
ex vivo visual assessment |
0.0 |
S4MH injection |
21 |
days |
|
|
|
108163 |
3119 |
ACI/SegHsd |
percentage of study population developing pituitary tumors during a period of time |
bilateral ovariectomy then 17 beta-estradiol (27.5 mg) (for 140 days) |
Shull JD, et al., Carcinogenesis. 1997 Aug;18(8):1595-601 |
pituitary gland integrity trait |
female |
201 days-203 days |
11 |
100.0 |
% |
|
|
ex vivo visual assessment |
0 |
|
0 |
|
|
|
|
65561 |
76 |
WF/Kga |
post-insult time to onset of moribundity |
controlled 4-nitroquinoline N-oxide content drinking water (10 mg/l) (for 180 days) |
Hirano M, et al., Cancer Lett 2005 May 2;. |
life span trait |
both |
42 days-222 days |
20 |
180.0 |
d |
0.0 |
0.0 |
ex vivo visual assessment |
0.0 |
|
0 |
|
|
180 day maximum |
|
70327 |
1339 |
DA/Slc |
post-insult time to onset of moribundity |
controlled 4-nitroquinoline N-oxide content drinking water (10 mg/l) (for 180 days) |
Hirano M, et al., Cancer Lett 2005 May 2;. |
life span trait |
both |
42 days-222 days |
20 |
161.45 |
d |
2.85 |
12.73 |
ex vivo visual assessment |
0.0 |
|
0 |
|
|
180 day maximum |
|
70329 |
1339 |
PVG |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral nerve myelin (2 mg) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
8 |
0.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84517 |
1178 |
LEW.1AR1/Ztm |
percentage of study population developing experimental autoimmune neuritis during a period of time |
peripheral nerve myelin (2 mg) and Freund's complete adjuvant (100 ul) |
de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. |
peripheral nervous system integrity trait |
male |
98 days-200 days |
30 |
100.0 |
% |
|
|
ex vivo visual assessment |
0.0 |
|
0 |
|
|
|
peripheral nervous system integrity trait |
84519 |
1178 |
LEW/NIcoCrlf |
defecation rate |
control condition |
Ramos A, et al., Behav Brain Res. 1998 Nov;96(1-2):195-205 |
defecation behavior trait |
female |
56 days-63 days |
6 |
0.0 |
/5 min |
0.0 |
0.0 |
ex vivo visual assessment |
300 |
|
0 |
|
video monitoring |
defecation rate measurement |
|
65139 |
108 |