Phenominer Database Results (157 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Site Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Record ID Study ID
SPRD.WKY-(D5Rat190-D5Rat114)/Ibmm mammary gland terminal end bud count control condition Lella V, et al., Int J Cancer. 2007 Oct 15;121(8):1738-43. mammary gland development trait female 55 days 5 59.3 null 2.6 5.81 ex vivo light microscopy 0 0 66136 709
ACI/SegHsd prostate tumorous lesion number control condition Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. prostate integrity trait male 900 days 12 5.3 null ex vivo light microscopy 0 0 65822 341
F344/Jcl percentage of study population developing testis tumors during a period of time control condition Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. testis integrity trait male 900 days 8 100.0 % ex vivo light microscopy 0.0 0 testis tumor incidence 65841 341
SHRSP.WKY-(Klk1-D1Rat116)/Izm percentage of study population developing cerebrovascular lesions during a period of time controlled sodium content drinking water (1 %) (for 14 days) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. cerebrovascular system integrity trait female 98 days 9 0.0 % ex vivo light microscopy MA:0000168 0 0 65299 115
SS.SR-(D7Mco19-D7Mco7)/Jr artery wall thickness to artery total diameter ratio controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. coronary artery integrity trait male 114 days-118 days 3 53.3 % 1.9 3.29 ex vivo light microscopy 0 0 65737 283
SHRSP/Izm brain infarction volume control condition (for 153 days) Yao H, et al., Physiol Genomics. 2007 Feb 27;. brain integrity trait male 153 days 17 103.4 mm3 6.01 24.8 ex vivo light microscopy 0 MCA occlusion 3 days 65951 567
F344/Jcl percentage of study population developing leukemia during a period of time control condition Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. leukocyte integrity trait male 900 days 8 25.0 % ex vivo light microscopy 0 0 leukemia incidence 66142 341
LEW/Rkb count of superficial glomeruli not directly contacting the kidney surface control condition Schulz A, et al., J Am Soc Nephrol 2002 Nov;13(11):2706-14. kidney glomerulus quantity not specified 126 days 8 6.3 null 1.1 3.1 ex vivo light microscopy 0.0 0 67600 769
LEW/Rkb count of superficial glomeruli directly contacting the kidney surface control condition Schulz A, et al., J Am Soc Nephrol 2002 Nov;13(11):2706-14. kidney glomerulus quantity not specified 126 days 8 0.0 null 0.0 0.0 ex vivo light microscopy 0.0 0 67602 769
BN/SsNHsd percentage of study population developing pituitary gland hyperplastic lesions during a period of time diethylstilbestrol (5 mg) (for 70 days) and surgical implantation (for 70 days) Pandey J, et al., Carcinogenesis 2004 May 27;. pituitary gland integrity trait not specified 91 days 6 100.0 % ex vivo light microscopy 0.0 surgery implant 70 days xco:0000295 69908 1240
BN/SsNHsd percentage of study population developing pituitary tumors that replace a portion of the gland during a period of time diethylstilbestrol (5 mg) (for 70 days) and surgical implantation (for 70 days) Pandey J, et al., Carcinogenesis 2004 May 27;. pituitary gland integrity trait not specified 91 days 6 0.0 % ex vivo light microscopy 0.0 surgery implant 70 days xco:0000295 69909 1240
F344/NHsd percentage of study population developing pituitary tumors that invade the glandular capsule during a period of time diethylstilbestrol (5 mg) (for 70 days) and surgical implantation (for 70 days) Pandey J, et al., Carcinogenesis 2004 May 27;. pituitary gland integrity trait not specified 91 days 6 50.0 % ex vivo light microscopy 0.0 surgery implant 70 days xco:0000295 69915 1240
SHR/Fub count of superficial glomeruli directly contacting the kidney surface control condition Schulz A, et al., J Am Soc Nephrol 2003 Dec;14(12):3081-9. kidney glomerulus quantity male 126 days 8 0.0 null 0.0 0.0 ex vivo light microscopy 0.0 0 67834 325
FHH/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy Shiozawa M, et al., J Am Soc Nephrol 2000 Nov;11(11):2068-78. kidney glomerulus integrity trait male 91 days-98 days 26 52.1 % 2.29 11.7 ex vivo light microscopy 0.0 unilateral nephrectomy 39 days performed at 5 to 6 weeks of age 69159 1128
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb percentage of study population developing cerebrovascular lesions during a period of time controlled sodium content diet (3.7 mg/g) (between 28 and 49 days) and controlled sodium content drinking water (1 %) (between 28 and 49 days) and controlled potassium content diet (6.3 mg/g) (between 28 and 49 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. cerebrovascular system integrity trait not specified 70 days-91 days 20 61.0 % ex vivo light microscopy 0.0 0 69121 1126
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy then NG-nitroarginine methyl ester (10-21 mg/kg/d) (for 126 days) van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 20.0 % 3.0 10.39 ex vivo light microscopy 0.0 unilateral nephrectomy 126 days Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68882 832
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio right nephrectomy then NG-nitroarginine methyl ester (50-150 mg/l) Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 15.0 % 1.0 3.46 ex vivo light microscopy 0.0 0 67722 62
BN/CrlCrlj percentage of study population developing chronic pancreatitis during a period of time controlled protein content diet Tsuji A, et al., Genomics 2001 Jun 15;74(3):365-9. pancreas integrity trait male 90 days 5 0.0 % ex vivo light microscopy 0.0 0 67773 321
WBN/KobSlc percentage of study population developing chronic pancreatitis during a period of time controlled protein content diet Tsuji A, et al., Genomics 2001 Jun 15;74(3):365-9. pancreas integrity trait male 150 days 5 100.0 % ex vivo light microscopy 0.0 0 67775 321
BN/CrlCrlj percentage of study population developing chronic pancreatitis during a period of time controlled protein content diet Tsuji A, et al., Genomics 2001 Jun 15;74(3):365-9. pancreas integrity trait male 120 days 5 0.0 % ex vivo light microscopy 0.0 0 67776 321
WF/CrCrli well differentiated malignant colorectal tumor number 1,2-dimethylhydrazine (20 mg/kg/week) (for 182 days) De Miglio MR, et al., Carcinogenesis. 2007 May 17;. colorectal integrity trait not specified 0 days 20 0.16 null 0.04 0.19 ex vivo light microscopy 0.0 0 70382 1378
LOU/MBbb number of ruptures of the internal elastic lamina of the renal arteries control condition Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. renal artery integrity trait male 120 days-126 days 8 0.13 null 0.12 0.35 ex vivo light microscopy 0.0 0 number of internal elastic lamina ruptures 96777 1680
LEW.BN-(D10Rat43-D10Mco4)/Rj percentage of study population displaying Toxoplasma gondii brain cysts at a point in time Toxoplasma gondii cysts (20 null) (for 42 days) Cavailles P, et al., Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):744-9. Epub 2006 Jan 6. brain integrity trait both 98 days-174 days 4 0.0 % ex vivo light microscopy 0.0 0 75681 1518
LEW.BN-(D10Mco17-D10Mco14)/Ciml percentage of study population displaying Toxoplasma gondii brain cysts at a point in time Toxoplasma gondii cysts (20 null) (for 42 days) Cavailles P, et al., Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):744-9. Epub 2006 Jan 6. brain integrity trait both 98 days-174 days 3 0.0 % ex vivo light microscopy 0.0 0 75682 1518
LEW.BN-(D10Arb4-D10Rat133)/Ciml percentage of study population displaying Toxoplasma gondii brain cysts at a point in time Toxoplasma gondii cysts (20 null) (for 42 days) Cavailles P, et al., Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):744-9. Epub 2006 Jan 6. brain integrity trait both 98 days-174 days 4 75.0 % ex vivo light microscopy 0.0 0 75684 1518
LEW.BN-(D10Mco17-D10Rat133)/Ciml percentage of study population displaying Toxoplasma gondii brain cysts at a point in time Toxoplasma gondii cysts (20 null) (for 42 days) Cavailles P, et al., Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):744-9. Epub 2006 Jan 6. brain integrity trait both 98 days-174 days 3 100.0 % ex vivo light microscopy 0.0 0 75687 1518
BN/Rj patent ductus arteriosus score control condition Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. artery integrity trait female 120 days-126 days 3 4.0 null 1.48 2.56 ex vivo light microscopy 0.0 0 score of PDA 96774 1680
LOU/MBbb number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries control condition Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. artery integrity trait male 120 days-126 days 8 0.0 null ex vivo light microscopy 0.0 0 number of internal elastic lamina ruptures 97048 1680
F344/Jcl prostate tumorous lesion number control condition Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. prostate integrity trait male 900 days 8 1.5 null ex vivo light microscopy 0 0 65823 341
SHRSP.WKY-(Klk1-D1Rat116)/Izm percentage of study population developing cerebrovascular lesions during a period of time controlled sodium content drinking water (1 %) (for 14 days) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. cerebrovascular system integrity trait male 98 days 13 0.0 % ex vivo light microscopy MA:0000168 0 0 65297 115
ACI.FHH-(D3Wox2-D3Rat59)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio right nephrectomy Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 20.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 67718 62
ACI.FHH-(D3Wox2-D3Rat59)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio right nephrectomy then NG-nitroarginine methyl ester (50-150 mg/l) Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 11 39.0 % 5.0 16.58 ex vivo light microscopy 0.0 0 67723 62
LOU/MBbb arterial internal elastic lamina rupture composite score control condition Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. artery integrity trait female 120 days-126 days 3 0.0 null ex vivo light microscopy 0.0 0 internal elastic lamina rupture score 97051 1680
F344/Jcl percentage of study population developing ventral prostate tumorous lesions during a period of time control condition Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. prostate integrity trait male 900 days 8 50.0 % ex vivo light microscopy 0 0 65824 341
BN/NHsdMcwi kidney glomerulus diameter controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. kidney glomerulus size trait female 97 days-101 days 22 95.0 um 1.2 5.63 ex vivo light microscopy 0.0 0 plasma creatinine analysis 67285 151
SHRSP/Izm percentage of study population developing cerebrovascular lesions during a period of time controlled sodium content drinking water (1 %) (for 14 days) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. cerebrovascular system integrity trait female 98 days 10 0.0 % ex vivo light microscopy MA:0000168 0 0 65292 115
SHRSP.WKY-(Klk1-D1Rat116)/Izm percentage of study population developing cerebrovascular lesions during a period of time controlled sodium content drinking water (1 %) (for 28 days) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. cerebrovascular system integrity trait male 112 days 9 0.0 % ex vivo light microscopy MA:0000168 0 0 65301 115
MWF/FubRkb count of superficial glomeruli not directly contacting the kidney surface control condition Schulz A, et al., J Am Soc Nephrol 2002 Nov;13(11):2706-14. kidney glomerulus quantity not specified 126 days 8 19.4 null 1.41 4.0 ex vivo light microscopy 0.0 0 67599 769
BN/SsNHsd percentage of study population developing pituitary tumors that replace the entire gland during a period of time diethylstilbestrol (5 mg) (for 70 days) and surgical implantation (for 70 days) Pandey J, et al., Carcinogenesis 2004 May 27;. pituitary gland integrity trait not specified 91 days 6 0.0 % ex vivo light microscopy 0.0 surgery implant 70 days xco:0000295 69910 1240
F344.BN-(D5Rat1-D5Mit5)/Dlw percentage of study population developing pituitary tumors that invade the glandular capsule during a period of time diethylstilbestrol (5 mg) (for 70 days) and surgical implantation (for 70 days) Pandey J, et al., Carcinogenesis 2004 May 27;. pituitary gland integrity trait not specified 91 days 6 67.0 % ex vivo light microscopy 0.0 surgery implant 70 days xco:0000295 69919 1240
SHR/Fub count of superficial glomeruli not directly contacting the kidney surface control condition Schulz A, et al., J Am Soc Nephrol 2003 Dec;14(12):3081-9. kidney glomerulus quantity male 126 days 8 0.1 null 0.11 0.3 ex vivo light microscopy 0.0 0 67831 325
LOU/Ins percentage of study population developing hematuria during a period of time control condition Kota LT, et al., Physiol Genomics. 2008 Jun 3;. kidney integrity trait male 126 days 20 0.0 % ex vivo light microscopy 0.0 0 68637 870
F344/Jcl percentage of study population developing bilateral testis tumors during a period of time control condition Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. testis integrity trait male 900 days 8 88.0 % ex vivo light microscopy 0.0 0 necropsy bilateral testis tumor incidence 67949 341
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio control condition van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 8.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68878 832
ACI.FHH-(D1Rat384-D1Rat452)(D17Rat61-D1Arb5)(D17Rat51)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy then NG-nitroarginine methyl ester (10-21 mg/kg/d) (for 126 days) van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 9 29.0 % 4.0 12.0 ex vivo light microscopy 0.0 unilateral nephrectomy 126 days Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68885 832
ACI.FHH-(D1Mit18-D1Mit8)(D14Mit11-D14Hmgc14b)(D14Rat65-D14Rat90)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio NG-nitroarginine methyl ester (9-16 mg/kg/d) (for 126 days) van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 33.0 % 3.0 10.39 ex vivo light microscopy 0.0 0 Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68888 832
ACI/SegHsd percentage of study population developing benign colorectal tumors during a period of time 1,2-dimethylhydrazine (20 mg/kg/week) (for 182 days) De Miglio MR, et al., Carcinogenesis. 2007 May 17;. colorectal integrity trait not specified 0 days 20 75.0 % ex vivo light microscopy 0.0 0 70376 1378
WF/CrCrli percentage of study population developing well differentiated malignant colorectal tumors during a period of time 1,2-dimethylhydrazine (20 mg/kg/week) (for 182 days) De Miglio MR, et al., Carcinogenesis. 2007 May 17;. colorectal integrity trait not specified 0 days 20 15.0 % ex vivo light microscopy 0.0 0 70379 1378
BN-Lx/Cub motile sperm count to total sperm count ratio control condition Zidek V, et al., J Reprod Fertil 1999 Jul;116(2):329-33. sperm quantity male 90 days 9 67.0 % 0.87 2.6 ex vivo light microscopy 0.0 0 69016 1076
SHR/OlaIpcv normal sperm count to total sperm count ratio control condition Zidek V, et al., J Reprod Fertil 1999 Jul;116(2):329-33. sperm quantity male 90 days 9 80.2 % 0.43 1.3 ex vivo light microscopy 0.0 0 normal sperm to total sperm ratio 69021 1076
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio control condition Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 9.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 67708 62
ACI.FHH-(D1Rat298-D1Rat90)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio control condition Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 14.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 67710 62
ACI.FHH-(D1Rat475-D1Rat90)(D3Rat84-D3Rat59)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio control condition Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 14.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 67711 62
BN/CrlCrlj percentage of study population developing chronic pancreatitis during a period of time controlled protein content diet Tsuji A, et al., Genomics 2001 Jun 15;74(3):365-9. pancreas integrity trait male 150 days 6 0.0 % ex vivo light microscopy 0.0 0 67777 321
ACI.FHH-(D1Mit18-D1Mit8)(D14Mit11-D14Hmgc14b)(D14Rat65-D14Rat90)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy then NG-nitroarginine methyl ester (10-21 mg/kg/d) (for 126 days) van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 2 59.0 % 11.0 15.56 ex vivo light microscopy 0.0 unilateral nephrectomy 126 days Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68884 832
BN/Rj arterial internal elastic lamina rupture composite score control condition Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. artery integrity trait male 120 days-126 days 7 118.7 null 7.14 18.9 ex vivo light microscopy 0.0 0 internal elastic lamina rupture score 96769 1680
BN/Rj arterial internal elastic lamina rupture composite score control condition Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. artery integrity trait female 120 days-126 days 3 65.0 null 21.82 37.8 ex vivo light microscopy 0.0 0 internal elastic lamina rupture score 96770 1680
BN.LEW-(D10Rat32-D10Mgh4)/Rj percentage of study population displaying Toxoplasma gondii brain cysts at a point in time Toxoplasma gondii cysts (20 null) (for 42 days) Cavailles P, et al., Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):744-9. Epub 2006 Jan 6. brain integrity trait both 98 days-174 days 5 0.0 % ex vivo light microscopy 0.0 0 75688 1518
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb percentage of study population developing cerebrovascular lesions during a period of time controlled sodium content diet (3.7 mg/g) (between 28 and 67 days) and controlled sodium content drinking water (1 %) (between 28 and 67 days) and controlled potassium content diet (6.3 mg/g) (between 28 and 67 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. cerebrovascular system integrity trait not specified 70 days-109 days 33 100.0 % ex vivo light microscopy 0.0 0 84575 1126
LOU/MBbb number of ruptures of the internal elastic lamina of the renal arteries control condition Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. renal artery integrity trait female 120 days-126 days 8 0.0 null ex vivo light microscopy 0.0 0 number of internal elastic lamina ruptures 97047 1680
LOU/MBbb arterial internal elastic lamina rupture composite score control condition Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. artery integrity trait male 120 days-126 days 8 0.0 null ex vivo light microscopy 0.0 0 internal elastic lamina rupture score 97050 1680
ACI/SegHsd percentage of study population developing ventral prostate tumorous lesions with a solid structure during a period of time control condition Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. prostate integrity trait male 900 days 12 92.0 % ex vivo light microscopy 0.0 0 109885 341
ACI/SegHsd percentage of study population developing ventral prostate tumorous lesions with round, irregular size nuclei during a period of time control condition Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. prostate integrity trait male 900 days 12 100.0 % ex vivo light microscopy 0.0 0 109957 341
ACI/SegHsd number of ventral prostate tumorous lesions with round, irregular size nuclei control condition Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. prostate integrity trait male 900 days 12 5.1 null 0.69 2.4 ex vivo light microscopy 0.0 0 109959 341
SHRSP.WKY-(Klk1-D1Rat116)/Izm percentage of study population developing cerebrovascular lesions during a period of time controlled sodium content drinking water (1 %) (for 28 days) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. cerebrovascular system integrity trait male 112 days 13 0.0 % ex vivo light microscopy MA:0000168 0 0 65300 115
ACI.FHH-(D3Wox2-D3Rat59)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio control condition Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 13.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 67709 62
SHR/OlaIpcv motile sperm count to total sperm count ratio control condition Zidek V, et al., J Reprod Fertil 1999 Jul;116(2):329-33. sperm quantity male 90 days 9 57.0 % 1.57 4.7 ex vivo light microscopy 0.0 0 69015 1076
ACI.FHH-(D1Rat384-D1Rat156)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio NG-nitroarginine methyl ester (9-16 mg/kg/d) (for 126 days) van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 20.0 % 3.0 10.39 ex vivo light microscopy 0.0 0 Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68887 832
ACI/SegHsd well differentiated malignant colorectal tumor number 1,2-dimethylhydrazine (20 mg/kg/week) (for 182 days) De Miglio MR, et al., Carcinogenesis. 2007 May 17;. colorectal integrity trait not specified 0 days 20 0.28 null 0.04 0.16 ex vivo light microscopy 0.0 0 70381 1378
ACI.FHH-(D1Mit18-D1Mit8)(D14Mit11-D14Hmgc14b)(D14Rat65-D14Rat90)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 30.0 % 3.0 10.39 ex vivo light microscopy 0.0 unilateral nephrectomy 126 days Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68876 832
SHRSP/Bbb percentage of study population developing cerebrovascular lesions during a period of time controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days) Rubattu S, et al., Nat Genet 1996 Aug;13(4):429-34 cerebrovascular system integrity trait both 84 days 30 100.0 % ex vivo light microscopy 0.0 0 69117 1125
SHRSP/Bbb percentage of study population developing cerebrovascular lesions during a period of time controlled sodium content diet (3.7 mg/g) (between 70 and 88 days) and controlled sodium content drinking water (1 %) (between 70 and 88 days) and controlled potassium content diet (6.3 mg/g) (between 70 and 88 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. cerebrovascular system integrity trait not specified 70 days-88 days 31 100.0 % ex vivo light microscopy 0.0 0 69119 1126
BN/Rj number of ruptures of the internal elastic lamina of the renal arteries control condition Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. renal artery integrity trait female 120 days-126 days 3 0.33 null 0.33 0.58 ex vivo light microscopy 0.0 0 number of internal elastic lamina ruptures 96772 1680
LEW.BN-(D10Mco17-D10Rat221)/Ciml percentage of study population displaying Toxoplasma gondii brain cysts at a point in time Toxoplasma gondii cysts (20 null) (for 42 days) Cavailles P, et al., Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):744-9. Epub 2006 Jan 6. brain integrity trait both 98 days-174 days 3 66.67 % ex vivo light microscopy 0.0 0 75683 1518
BN.LEW-(D10Mco17-D10Mco14)/Ciml percentage of study population displaying Toxoplasma gondii brain cysts at a point in time Toxoplasma gondii cysts (20 null) (for 42 days) Cavailles P, et al., Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):744-9. Epub 2006 Jan 6. brain integrity trait both 98 days-174 days 5 40.0 % ex vivo light microscopy 0.0 0 75689 1518
SHRSP.WKY-(D1Wox29-D1Arb21)/Izm brain infarction volume control condition (for 153 days) Yao H, et al., Physiol Genomics. 2007 Feb 27;. brain integrity trait male 153 days 15 66.4 mm3 5.55 21.5 ex vivo light microscopy 0 MCA occlusion 3 days 65950 567
SHRSP/Izm percentage of study population developing cerebrovascular lesions during a period of time controlled sodium content drinking water (1 %) (for 14 days) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. cerebrovascular system integrity trait male 98 days 12 50.0 % ex vivo light microscopy MA:0000168 0 0 65291 115
SS.SR-(D3Arb14-D3Mco36)/Mco artery wall thickness to artery total diameter ratio controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. coronary artery integrity trait male 114 days-118 days 6 55.0 % 3.4 8.33 ex vivo light microscopy 0 0 65735 283
F344/NHsd percentage of study population developing pituitary gland hyperplastic lesions during a period of time diethylstilbestrol (5 mg) (for 70 days) and surgical implantation (for 70 days) Pandey J, et al., Carcinogenesis 2004 May 27;. pituitary gland integrity trait not specified 91 days 6 0.0 % ex vivo light microscopy 0.0 surgery implant 70 days xco:0000295 69912 1240
F344/NHsd percentage of study population developing pituitary tumors that replace a portion of the gland during a period of time diethylstilbestrol (5 mg) (for 70 days) and surgical implantation (for 70 days) Pandey J, et al., Carcinogenesis 2004 May 27;. pituitary gland integrity trait not specified 91 days 6 50.0 % ex vivo light microscopy 0.0 surgery implant 70 days xco:0000295 69913 1240
F344.BN-(D5Rat1-D5Mit5)/Dlw lactotroph count to total pituicyte count ratio in prolactinoma diethylstilbestrol (5 mg) (for 70 days) and surgical implantation (for 70 days) Pandey J, et al., Carcinogenesis 2004 May 27;. pituitary gland integrity trait not specified 91 days 6 86.0 % 9.0 22.05 ex vivo light microscopy 0.0 surgery implant 70 days xco:0000295 lactotroph to total pituicyte ratio 69920 1240
ACI.FHH-(D17Rat117-D17Arb5)(D17Rat180-D17Rat51)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio controlled hydrogen ion content drinking water (2.4-2.8 pH) Van Dijk SJ, et al., Nephron Exp Nephrol 2005 Jun 20;101(2):e59-e66. kidney glomerulus integrity trait male 173 days-180 days 7 2.0 % 1.0 2.65 ex vivo light microscopy 0.0 0 67951 751
SHRSR/Bbb percentage of study population developing cerebrovascular lesions during a period of time controlled sodium content diet (3.7 mg/g) (for 84 days) and controlled sodium content drinking water (1 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. cerebrovascular system integrity trait not specified 126 days 18 0.0 % ex vivo light microscopy 0.0 0 69120 1126
SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb percentage of study population developing cerebrovascular lesions during a period of time controlled sodium content diet (3.7 mg/g) (between 42 and 91 days) and controlled sodium content drinking water (1 %) (between 42 and 91 days) and controlled potassium content diet (6.3 mg/g) (between 42 and 91 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. cerebrovascular system integrity trait not specified 81 days-133 days 31 20.0 % ex vivo light microscopy 0.0 0 69124 1126
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio controlled hydrogen ion content drinking water (2.4-2.8 pH) Van Dijk SJ, et al., Nephron Exp Nephrol 2005 Jun 20;101(2):e59-e66. kidney glomerulus integrity trait male 173 days-180 days 8 8.0 % 2.0 5.66 ex vivo light microscopy 0.0 0 67950 751
WF/CrCrli benign colorectal tumor number 1,2-dimethylhydrazine (20 mg/kg/week) (for 182 days) De Miglio MR, et al., Carcinogenesis. 2007 May 17;. colorectal integrity trait not specified 0 days 20 0.25 null 0.14 0.62 ex vivo light microscopy 0.0 0 70377 1378
ACI.FHH-(D3Wox2-D3Rat59)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio NG-nitroarginine methyl ester (50-150 mg/l) Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 18.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 67714 62
WBN/KobSlc percentage of study population developing chronic pancreatitis during a period of time controlled protein content diet Tsuji A, et al., Genomics 2001 Jun 15;74(3):365-9. pancreas integrity trait male 120 days 5 100.0 % ex vivo light microscopy 0.0 0 67774 321
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 15.0 % 3.0 10.39 ex vivo light microscopy 0.0 unilateral nephrectomy 126 days Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68874 832
ACI.FHH-(D1Rat384-D1Rat156)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio control condition van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 14.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68879 832
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio NG-nitroarginine methyl ester (9-16 mg/kg/d) (for 126 days) van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 11.0 % 1.0 3.46 ex vivo light microscopy 0.0 0 Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68886 832
BN/Rj number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries control condition Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. artery integrity trait male 120 days-126 days 7 59.4 null 3.67 9.7 ex vivo light microscopy 0.0 0 number of internal elastic lamina ruptures 96767 1680
LOU/MBbb patent ductus arteriosus score control condition Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. artery integrity trait female 120 days-126 days 10 0.17 null 0.17 0.54 ex vivo light microscopy 0.0 0 score of PDA 96776 1680
BN.LEW-(D10Mco17-D10Rat80)/Ciml percentage of study population displaying Toxoplasma gondii brain cysts at a point in time Toxoplasma gondii cysts (20 null) (for 42 days) Cavailles P, et al., Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):744-9. Epub 2006 Jan 6. brain integrity trait both 98 days-174 days 5 0.0 % ex vivo light microscopy 0.0 0 75690 1518
SHRSP.SHRSR-(D1Rat134-Mt1-ps1)/Bbb percentage of study population developing cerebrovascular lesions during a period of time controlled sodium content diet (3.7 mg/g) (between 28 and 91 days) and controlled sodium content drinking water (1 %) (between 28 and 91 days) and controlled potassium content diet (6.3 mg/g) (between 28 and 91 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. cerebrovascular system integrity trait not specified 70 days-133 days 35 100.0 % ex vivo light microscopy 0.0 0 84576 1126
LOU/MBbb number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries control condition Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. artery integrity trait female 120 days-126 days 3 0.0 null ex vivo light microscopy 0.0 0 number of internal elastic lamina ruptures 97049 1680
F344/Jcl number of ventral prostate tumorous lesions with solid structure control condition Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. prostate integrity trait male 900 days 8 0.4 null 0.25 0.7 ex vivo light microscopy 0.0 0 109888 341
WF/CrCrli percentage of study population developing benign colorectal tumors during a period of time 1,2-dimethylhydrazine (20 mg/kg/week) (for 182 days) De Miglio MR, et al., Carcinogenesis. 2007 May 17;. colorectal integrity trait not specified 0 days 20 25.0 % ex vivo light microscopy 0.0 0 70375 1378
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio NG-nitroarginine methyl ester (50-150 mg/l) Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 11.0 % 1.0 3.46 ex vivo light microscopy 0.0 0 67712 62
ACI.FHH-(D1Rat298-D1Rat90)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio NG-nitroarginine methyl ester (50-150 mg/l) Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 23.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 67715 62
ACI.FHH-(D1Mit18-D1Mit8)(D14Mit11-D14Hmgc14b)(D14Rat65-D14Rat90)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio control condition van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 21.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68880 832
ACI/SegHsd percentage of study population developing poorly differentiated malignant colorectal tumors during a period of time 1,2-dimethylhydrazine (20 mg/kg/week) (for 182 days) De Miglio MR, et al., Carcinogenesis. 2007 May 17;. colorectal integrity trait not specified 0 days 20 15.0 % ex vivo light microscopy 0.0 0 70384 1378
MWF/FubRkb count of superficial glomeruli directly contacting the kidney surface control condition Schulz A, et al., J Am Soc Nephrol 2002 Nov;13(11):2706-14. kidney glomerulus quantity not specified 126 days 8 2.9 null 0.57 1.6 ex vivo light microscopy 0.0 0 67601 769
SPRD.WKY-(D18Wox8-D18Rat44)/Ibmm mammary gland terminal end bud count control condition Lella V, et al., Int J Cancer. 2007 Oct 15;121(8):1738-43. mammary gland development trait female 55 days 5 60.3 null 4.9 10.96 ex vivo light microscopy 0 0 66137 709
ACI/SegHsd percentage of study population developing testis tumors during a period of time control condition Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. testis integrity trait male 900 days 12 92.0 % ex vivo light microscopy 0.0 0 testis tumor incidence 65840 341
SHRSP/Izm percentage of study population developing cerebrovascular lesions during a period of time controlled sodium content drinking water (1 %) (for 28 days) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. cerebrovascular system integrity trait male 112 days 12 100.0 % ex vivo light microscopy MA:0000168 0 0 65294 115
SHRSP/Izm percentage of study population developing cerebrovascular lesions during a period of time controlled sodium content drinking water (1 %) (for 28 days) Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. cerebrovascular system integrity trait female 112 days 10 60.0 % ex vivo light microscopy MA:0000168 0 0 65295 115
SS/Jr artery wall thickness to artery total diameter ratio controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. coronary artery integrity trait male 114 days-118 days 3 54.0 % 7.0 12.12 ex vivo light microscopy 0 0 65738 283
ACI/SegHsd percentage of study population developing leukemia during a period of time control condition Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. leukocyte integrity trait male 900 days 12 0.0 % ex vivo light microscopy 0 0 leukemia incidence 66143 341
BN/SsNHsd percentage of study population developing pituitary tumors that invade the glandular capsule during a period of time diethylstilbestrol (5 mg) (for 70 days) and surgical implantation (for 70 days) Pandey J, et al., Carcinogenesis 2004 May 27;. pituitary gland integrity trait not specified 91 days 6 0.0 % ex vivo light microscopy 0.0 surgery implant 70 days xco:0000295 69911 1240
F344/NHsd percentage of study population developing pituitary tumors that replace the entire gland during a period of time diethylstilbestrol (5 mg) (for 70 days) and surgical implantation (for 70 days) Pandey J, et al., Carcinogenesis 2004 May 27;. pituitary gland integrity trait not specified 91 days 6 50.0 % ex vivo light microscopy 0.0 surgery implant 70 days xco:0000295 69914 1240
MWF/Fub count of superficial glomeruli not directly contacting the kidney surface control condition Schulz A, et al., J Am Soc Nephrol 2003 Dec;14(12):3081-9. kidney glomerulus quantity male 126 days 8 19.4 null 1.41 4.0 ex vivo light microscopy 0.0 0 67827 325
WF/CrCrli percentage of study population developing poorly differentiated malignant colorectal tumors during a period of time 1,2-dimethylhydrazine (20 mg/kg/week) (for 182 days) De Miglio MR, et al., Carcinogenesis. 2007 May 17;. colorectal integrity trait not specified 0 days 20 80.0 % ex vivo light microscopy 0.0 0 70383 1378
WF/CrCrli poorly differentiated malignant colorectal tumor number 1,2-dimethylhydrazine (20 mg/kg/week) (for 182 days) De Miglio MR, et al., Carcinogenesis. 2007 May 17;. colorectal integrity trait not specified 0 days 20 1.08 null 0.06 0.29 ex vivo light microscopy 0.0 0 70385 1378
WF/CrCrli poorly differentiated malignant colorectal tumor number 1,2-dimethylhydrazine (20 mg/kg/week) (for 182 days) De Miglio MR, et al., Carcinogenesis. 2007 May 17;. colorectal integrity trait not specified 0 days 20 0.21 null 0.05 0.22 ex vivo light microscopy 0.0 0 70386 1378
SHR/Bbb percentage of study population developing cerebrovascular lesions during a period of time controlled sodium content diet (3.7 mg/g) (for 140 days) and controlled sodium content drinking water (1 %) (for 140 days) and controlled potassium content diet (6.3 mg/g) (for 140 days) Rubattu S, et al., Nat Genet 1996 Aug;13(4):429-34 cerebrovascular system integrity trait both 182 days 30 20.0 % ex vivo light microscopy 0.0 0 69118 1125
SHRSP.SHRSR-(D1Rat134-Mt1-ps1)/Bbb percentage of study population developing cerebrovascular lesions during a period of time controlled sodium content diet (3.7 mg/g) (between 28 and 49 days) and controlled sodium content drinking water (1 %) (between 28 and 49 days) and controlled potassium content diet (6.3 mg/g) (between 28 and 49 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. cerebrovascular system integrity trait not specified 70 days-91 days 34 63.0 % ex vivo light microscopy 0.0 0 69122 1126
BN/Rj percentage of study population developing hematuria during a period of time control condition Kota LT, et al., Physiol Genomics. 2008 Jun 3;. kidney integrity trait male 126 days 60 16.7 % ex vivo light microscopy 0.0 0 68638 870
ACI/SegHsd percentage of study population developing bilateral testis tumors during a period of time control condition Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. testis integrity trait male 900 days 12 25.0 % ex vivo light microscopy 0.0 0 necropsy bilateral testis tumor incidence 67948 341
ACI.FHH-(D1Rat384-D1Rat156)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 13.0 % 2.0 6.93 ex vivo light microscopy 0.0 unilateral nephrectomy 126 days Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68875 832
ACI/SegHsd percentage of study population developing well differentiated malignant colorectal tumors during a period of time 1,2-dimethylhydrazine (20 mg/kg/week) (for 182 days) De Miglio MR, et al., Carcinogenesis. 2007 May 17;. colorectal integrity trait not specified 0 days 20 20.0 % ex vivo light microscopy 0.0 0 70380 1378
ACI.FHH-(D1Rat475-D1Rat90)(D3Rat84-D3Rat59)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio NG-nitroarginine methyl ester (50-150 mg/l) Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 31.0 % 6.0 20.78 ex vivo light microscopy 0.0 0 67716 62
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio right nephrectomy Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 15.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 67717 62
ACI.FHH-(D1Rat475-D1Rat90)(D3Rat84-D3Rat59)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio right nephrectomy then NG-nitroarginine methyl ester (50-150 mg/l) Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 5 64.0 % 11.0 24.6 ex vivo light microscopy 0.0 0 67725 62
LEW.BN-(D10Mgh7-D10Rat221)/Ciml percentage of study population displaying Toxoplasma gondii brain cysts at a point in time Toxoplasma gondii cysts (20 null) (for 42 days) Cavailles P, et al., Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):744-9. Epub 2006 Jan 6. brain integrity trait both 98 days-174 days 4 100.0 % ex vivo light microscopy 0.0 0 75685 1518
F344/Jcl percentage of study population developing ventral prostate tumorous lesions with a solid structure during a period of time control condition Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. prostate integrity trait male 900 days 8 25.0 % ex vivo light microscopy 0.0 0 109886 341
ACI/SegHsd number of ventral prostate tumorous lesions with solid structure control condition Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. prostate integrity trait male 900 days 12 3.0 null 0.75 2.6 ex vivo light microscopy 0.0 0 109887 341
F344/Jcl percentage of study population developing ventral prostate tumorous lesions with round, irregular size nuclei during a period of time control condition Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. prostate integrity trait male 900 days 8 38.0 % ex vivo light microscopy 0.0 0 109958 341
F344/Jcl number of ventral prostate tumorous lesions with round, irregular size nuclei control condition Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. prostate integrity trait male 900 days 8 1.3 null 0.64 1.8 ex vivo light microscopy 0.0 0 109960 341
SPRD/Ztm mammary gland terminal end bud count control condition Lella V, et al., Int J Cancer. 2007 Oct 15;121(8):1738-43. mammary gland development trait female 55 days 5 84.6 null 12.4 27.73 ex vivo light microscopy 0 0 66135 709
ACI.FHH-(D1Rat475-D1Rat90)(D3Rat84-D3Rat59)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio right nephrectomy Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 27.0 % 3.0 10.39 ex vivo light microscopy 0.0 0 67720 62
ACI.FHH-(D1Rat384-D1Rat156)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy then NG-nitroarginine methyl ester (10-21 mg/kg/d) (for 126 days) van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 11 42.0 % 6.0 19.9 ex vivo light microscopy 0.0 unilateral nephrectomy 126 days Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68883 832
ACI.FHH-(D1Rat324-D1Rat156)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio controlled hydrogen ion content drinking water (2.4-2.8 pH) Van Dijk SJ, et al., Nephron Exp Nephrol 2005 Jun 20;101(2):e59-e66. kidney glomerulus integrity trait male 173 days-180 days 8 15.0 % 3.0 8.49 ex vivo light microscopy 0.0 0 67952 751
SHRSR.SHRSP-(Klk1-Mt1-ps1)/Bbb percentage of study population developing cerebrovascular lesions during a period of time controlled sodium content diet (3.7 mg/g) (between 42 and 91 days) and controlled sodium content drinking water (1 %) (between 42 and 91 days) and controlled potassium content diet (6.3 mg/g) (between 42 and 91 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. cerebrovascular system integrity trait not specified 81 days-133 days 33 20.0 % ex vivo light microscopy 0.0 0 69123 1126
BN/Rj number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries control condition Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. artery integrity trait female 120 days-126 days 3 36.3 null 10.39 18.0 ex vivo light microscopy 0.0 0 number of internal elastic lamina ruptures 96768 1680
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco artery wall thickness to artery total diameter ratio controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. coronary artery integrity trait male 114 days-118 days 6 57.3 % 3.9 9.55 ex vivo light microscopy 0 0 65736 283
BN/Rj patent ductus arteriosus score control condition Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. artery integrity trait male 120 days-126 days 61 3.78 null 0.37 2.86 ex vivo light microscopy 0.0 0 score of PDA 96773 1680
WKY/Ztm mammary gland terminal end bud count control condition Lella V, et al., Int J Cancer. 2007 Oct 15;121(8):1738-43. mammary gland development trait female 55 days 5 33.8 null 2.1 4.7 ex vivo light microscopy 0 0 66138 709
ACI/SegHsd percentage of study population developing ventral prostate tumorous lesions during a period of time control condition Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. prostate integrity trait male 900 days 12 100.0 % ex vivo light microscopy 0 0 65825 341
SS/JrHsdMcwi kidney glomerulus diameter controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. kidney glomerulus size trait female 97 days-101 days 16 117.0 um 3.8 15.2 ex vivo light microscopy 0.0 0 plasma creatinine analysis glomerular diameter 67286 151
MWF/Fub count of superficial glomeruli directly contacting the kidney surface control condition Schulz A, et al., J Am Soc Nephrol 2003 Dec;14(12):3081-9. kidney glomerulus quantity male 126 days 8 2.9 null 0.57 1.6 ex vivo light microscopy 0.0 0 67833 325
F344.BN-(D5Rat1-D5Mit5)/Dlw percentage of study population developing pituitary gland hyperplastic lesions during a period of time diethylstilbestrol (5 mg) (for 70 days) and surgical implantation (for 70 days) Pandey J, et al., Carcinogenesis 2004 May 27;. pituitary gland integrity trait not specified 91 days 6 0.0 % ex vivo light microscopy 0.0 surgery implant 70 days xco:0000295 69916 1240
F344.BN-(D5Rat1-D5Mit5)/Dlw percentage of study population developing pituitary tumors that replace a portion of the gland during a period of time diethylstilbestrol (5 mg) (for 70 days) and surgical implantation (for 70 days) Pandey J, et al., Carcinogenesis 2004 May 27;. pituitary gland integrity trait not specified 91 days 6 67.0 % ex vivo light microscopy 0.0 surgery implant 70 days xco:0000295 69917 1240
F344.BN-(D5Rat1-D5Mit5)/Dlw percentage of study population developing pituitary tumors that replace the entire gland during a period of time diethylstilbestrol (5 mg) (for 70 days) and surgical implantation (for 70 days) Pandey J, et al., Carcinogenesis 2004 May 27;. pituitary gland integrity trait not specified 91 days 6 33.0 % ex vivo light microscopy 0.0 surgery implant 70 days xco:0000295 69918 1240
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy Shiozawa M, et al., J Am Soc Nephrol 2000 Nov;11(11):2068-78. kidney glomerulus integrity trait male 91 days-98 days 21 3.2 % 0.39 1.8 ex vivo light microscopy 0.0 unilateral nephrectomy 39 days performed at 5 to 6 weeks of age 69158 1128
ACI.FHH-(D1Rat384-D1Rat452)(D17Rat61-D1Arb5)(D17Rat51)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 12.0 % 2.0 6.93 ex vivo light microscopy 0.0 unilateral nephrectomy 126 days Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68877 832
ACI.FHH-(D1Rat384-D1Rat452)(D17Rat61-D1Arb5)(D17Rat51)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio control condition van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 8.0 % 1.0 3.46 ex vivo light microscopy 0.0 0 Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68881 832
ACI.FHH-(D1Rat298-D1Rat90)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio right nephrectomy Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 23.0 % 3.0 10.39 ex vivo light microscopy 0.0 0 67719 62
ACI.FHH-(D1Rat298-D1Rat90)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio right nephrectomy then NG-nitroarginine methyl ester (50-150 mg/l) Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 37.0 % 4.0 13.86 ex vivo light microscopy 0.0 0 67724 62
WBN/KobSlc percentage of study population developing chronic pancreatitis during a period of time controlled protein content diet Tsuji A, et al., Genomics 2001 Jun 15;74(3):365-9. pancreas integrity trait male 90 days 13 69.0 % ex vivo light microscopy 0.0 0 67772 321
ACI.FHH-(D1Rat384-D1Rat452)(D17Rat61-D1Arb5)(D17Rat51)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio NG-nitroarginine methyl ester (9-16 mg/kg/d) (for 126 days) van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 14.0 % 7.0 24.25 ex vivo light microscopy 0.0 0 Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68889 832
LOU/MBbb patent ductus arteriosus score control condition Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. artery integrity trait male 120 days-126 days 27 0.28 null 0.13 0.68 ex vivo light microscopy 0.0 0 score of PDA 96775 1680
ACI/SegHsd benign colorectal tumor number 1,2-dimethylhydrazine (20 mg/kg/week) (for 182 days) De Miglio MR, et al., Carcinogenesis. 2007 May 17;. colorectal integrity trait not specified 0 days 20 1.5 null 0.31 1.4 ex vivo light microscopy 0.0 0 70378 1378
BN-Lx/Cub normal sperm count to total sperm count ratio control condition Zidek V, et al., J Reprod Fertil 1999 Jul;116(2):329-33. sperm quantity male 90 days 9 84.8 % 0.8 2.4 ex vivo light microscopy 0.0 0 normal sperm to total sperm ratio 69022 1076
BN/Rj number of ruptures of the internal elastic lamina of the renal arteries control condition Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. renal artery integrity trait male 120 days-126 days 7 2.14 null 0.55 1.46 ex vivo light microscopy 0.0 0 number of internal elastic lamina ruptures 96771 1680
LEW.BN-(D10Rat32-D10Rat133)/Ciml percentage of study population displaying Toxoplasma gondii brain cysts at a point in time Toxoplasma gondii cysts (20 null) (for 42 days) Cavailles P, et al., Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):744-9. Epub 2006 Jan 6. brain integrity trait both 98 days-174 days 4 75.0 % ex vivo light microscopy 0.0 0 75686 1518
BN.LEW-(D10Rat32-D10Rat133)/Ciml percentage of study population displaying Toxoplasma gondii brain cysts at a point in time Toxoplasma gondii cysts (20 null) (for 42 days) Cavailles P, et al., Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):744-9. Epub 2006 Jan 6. brain integrity trait both 98 days-174 days 5 0.0 % ex vivo light microscopy 0.0 0 75691 1518