SS.SR-(D13Mit9-D13Mit1)/Jr |
heart weight to body weight ratio |
controlled sodium content diet (1 %) (for 60 days) then controlled sodium content diet (0.2 %) (for 40 days) |
Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 |
heart mass |
male |
134 days
| 11 |
|
|
3.3 |
g/kg |
|
|
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
66114 |
650 |
SS-Ncf2em1Mcwi-/- |
left kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
6 |
|
|
1.4 |
g |
0.05 |
0.11 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66750 |
717 |
SS-Ulk4em3Mcwi-/- |
left kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
4 |
|
|
1.55 |
g |
0.09 |
0.18 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66756 |
717 |
SS-Acad10em2Mcwi-/- |
left kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
12 |
|
|
1.51 |
g |
0.03 |
0.12 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66758 |
717 |
SS-Mthfrem1Mcwi+/+ |
left kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
1 |
|
|
1.63 |
g |
|
|
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66759 |
717 |
SS-Gpr183em2Mcwi-/- |
left kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
9 |
|
|
1.54 |
g |
0.05 |
0.14 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66764 |
717 |
SHR.BN-(D2Rat171-D2Arb24)/Ipcv |
heart weight to body weight ratio |
control condition |
Pravenec M, et al., J Hypertens 2001 Jun;19(6):1061-4. |
heart mass |
male |
100 days
| 8 |
|
|
3.78 |
g/kg |
0.05 |
0.14 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
11282 |
61 |
SHR.BN-(D5Wox12-D5Wox20)/Ipcv |
both kidneys wet weight to body weight ratio |
control condition |
Pravenec M, et al., Physiol Res 2003;52(3):285-9. |
kidney mass |
male |
80 days-100 days |
8 |
|
|
6.9 |
g/kg |
0.24 |
0.68 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
65508 |
612 |
OLETF/Got |
abdominal fat pad weight |
control condition |
Ogino Genom 2000 Nov 15;70(1):19-25. |
abdominal fat pad mass |
male |
252 days
| 14 |
|
|
78.8 |
g |
2.14 |
8.0 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
11407 |
83 |
F344.GK-(D1Mgh10-D1Rat119)/Swe |
epididymal fat pad weight |
control condition |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
epididymal fat pad mass |
male |
185 days
| 10 |
|
|
12.4 |
g |
0.3 |
0.95 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
11484 |
85 |
BN.GH-(D18Rat41-D18Mgh4)/Mcwi |
kidney wet weight |
angiotensin II (5-50 ng/kg/min) (between 0.2 and 1 hours) then norepinephrine (0.1-1 ug/kg/min) (between 0.2 and 1 hours) then phenylephrine (4 ug/kg) (between 0 and 0 hours) |
Bilusic M, et al., Croat Med J. 2008 Oct;49(5):586-99. |
kidney mass |
male |
132 days-146 days |
21 |
|
|
1.17 |
g |
0.04 |
0.2 |
post excision weight measurement |
|
|
|
0 |
|
ng/kg/min |
|
|
|
11546 |
101 |
SHR/Izm |
heart left ventricle wet weight |
control condition |
Tsujita Y, et al., Am J Physiol Heart Circ Physiol 2000 Nov;279(5):H2062-7 |
heart left ventricle mass |
male |
168 days
| 6 |
|
|
0.94 |
g |
0.01 |
0.02 |
post excision weight measurement |
|
|
|
0 |
|
polyethylene catheter (PE-50) |
|
|
|
11583 |
103 |
WKY/NCruk |
left kidney wet weight |
control condition |
Clemitson JR, et al., Hypertension 2002 Sep;40(3):292-7 |
kidney mass |
male |
175 days
| 19 |
|
|
1.21 |
g |
0.04 |
0.16 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
11643 |
110 |
COP/OlaHsd |
heart weight to body weight ratio |
running on inclined treadmill (10 m/min) (for 0.1 hours) |
Lee SJ, et al., Physiol Genomics 2005 Jul 20;. |
heart mass |
male |
105 days
| 4 |
|
|
2.17 |
g/kg |
|
|
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
13339 |
345 |
F344/NSlc |
mesenteric fat pad weight |
specific pathogen-free condition (for 210 days) then fasting (for 1 days) |
Kose H, et al., Mamm Genome. 2007 Aug;18(8):609-15. Epub 2007 Aug 21. |
mesenteric fat pad mass |
male |
218 days
| 7 |
|
|
7.0 |
g |
0.7 |
1.85 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
12780 |
311 |
F344/NSlc |
epididymal fat pad weight |
specific pathogen-free condition (for 210 days) then fasting (for 1 days) |
Kose H, et al., Mamm Genome. 2007 Aug;18(8):609-15. Epub 2007 Aug 21. |
epididymal fat pad mass |
male |
218 days
| 7 |
|
|
10.4 |
g |
0.7 |
1.85 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
12782 |
311 |
SS-Rag1em1Mcwi+/+ |
left kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
4 |
|
|
1.53 |
g |
0.07 |
0.13 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66788 |
717 |
SS-Bcas3em4Mcwi+/+ |
left kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
1 |
|
|
1.38 |
g |
|
|
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66796 |
717 |
SS-Tfdp2em2Mcwi-/- |
left kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
3 |
|
|
1.37 |
g |
0.01 |
0.02 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66798 |
717 |
SS-Cybaem1Mcwi+/+ |
left kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
2 |
|
|
1.52 |
g |
0.11 |
0.15 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66799 |
717 |
SS-Renem1Mcwi-/- |
left kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
5 |
|
|
1.89 |
g |
0.14 |
0.31 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66802 |
717 |
LEW |
heart right ventricle weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
heart right ventricle mass |
male |
98 days
| 6 |
|
|
0.54 |
mg/g |
0.01 |
0.01 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
64891 |
226 |
SS.LEW-(D18Rat61-D18Rat45)/Ayd |
heart left ventricle weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
heart left ventricle mass |
male |
98 days
| 6 |
|
|
2.61 |
mg/g |
0.08 |
0.2 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
64900 |
226 |
SS.LEW-(D16Got3-D16Rat112)/Ayd |
heart right ventricle weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
heart right ventricle mass |
male |
98 days
| 9 |
|
|
0.57 |
mg/g |
0.0 |
0.01 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
64909 |
226 |
SS.LEW-(D10Chm128-D10Chm169)/Ayd |
heart left ventricle weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
heart left ventricle mass |
male |
98 days
| 8 |
|
|
2.97 |
mg/g |
0.08 |
0.23 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
64914 |
226 |
SS.LEW-(D3Got33-D3Chm68)/Ayd |
heart right ventricle weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
heart right ventricle mass |
male |
98 days
| 10 |
|
|
0.62 |
mg/g |
0.01 |
0.03 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
64945 |
226 |
SS-Chr 19SHR/Rkb |
heart right ventricle weight to body weight ratio |
controlled sodium content diet (0.2 %) (for 56 days) |
Wendt N, et al., J Hypertens. 2007 Jan;25(1):95-102. |
heart right ventricle mass |
male |
98 days
| 20 |
|
|
0.51 |
mg/g |
0.01 |
0.04 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
66092 |
669 |
SS-Ulk4em3Mcwi-/- |
heart wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
heart mass |
male |
70 days-77 days |
4 |
|
|
1.26 |
g |
0.05 |
0.11 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
67000 |
717 |
SS-Apoeem7Mcwi+/+ |
heart wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
heart mass |
male |
70 days-77 days |
3 |
|
|
1.16 |
g |
0.06 |
0.1 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
67018 |
717 |
SS-Apoeem7Mcwi-/- |
heart wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
heart mass |
male |
70 days-77 days |
5 |
|
|
1.1 |
g |
0.03 |
0.06 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
67023 |
717 |
SS-Rag1em2Mcwi+/+ |
heart wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
heart mass |
male |
70 days-77 days |
1 |
|
|
1.05 |
g |
|
|
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
67041 |
717 |
SS-Renem1Mcwi-/- |
heart wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
heart mass |
male |
70 days-77 days |
5 |
|
|
0.99 |
g |
0.04 |
0.09 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
67046 |
717 |
F344/NSlc |
mesenteric fat pad weight |
control condition |
Kose H, et al., Exp Anim. 2008 Apr;57(2):135-8. |
mesenteric fat pad mass |
male |
217 days
| 9 |
|
|
8.9 |
g |
0.6 |
1.8 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
66186 |
716 |
F344/NSlc |
retroperitoneal fat pad weight |
control condition |
Kose H, et al., Exp Anim. 2008 Apr;57(2):135-8. |
retroperitoneal fat pad mass |
male |
217 days
| 9 |
|
|
10.3 |
g |
0.7 |
2.1 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
66188 |
716 |
F344/NSlc |
epididymal fat pad weight to body weight ratio |
control condition |
Kose H, et al., Exp Anim. 2008 Apr;57(2):135-8. |
epididymal fat pad mass |
male |
217 days
| 9 |
|
|
2.62 |
% |
0.22 |
0.66 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
66196 |
716 |
F344.OLETF-(D8Rat58-D8Mgh17)/Tj |
epididymal fat pad weight to body weight ratio |
control condition |
Kose H, et al., Exp Anim. 2008 Apr;57(2):135-8. |
epididymal fat pad mass |
male |
217 days
| 20 |
|
|
2.57 |
% |
0.05 |
0.22 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
66197 |
716 |
OLETF |
abdominal fat pad weight |
control condition (for 16 hours) |
Watanabe TK, et al., Genomics 1999 Jun 15;58(3):233-9. |
abdominal fat pad mass |
male |
210 days
| 5 |
|
|
60.8 |
g |
|
|
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
67220 |
312 |
SS.MNS-(D2Chm25-Fgg)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98 days
| 9 |
|
|
10.6 |
g/kg |
0.2 |
0.6 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
64794 |
226 |
SS.MNS-(D2Wox27-Adh1)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98 days
| 5 |
|
|
10.3 |
g/kg |
0.2 |
0.45 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
64796 |
226 |
SS.LEW-(D2Rat199-D2Mco17)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98 days
| 8 |
|
|
11.4 |
g/kg |
0.6 |
1.7 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
64799 |
226 |
F344/Jcl |
both testes wet weight |
control condition |
Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. |
testis mass |
male |
900 days
| 8 |
|
|
6.62 |
g |
|
|
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
65821 |
341 |
SS.SR-Inha/Jr |
heart wet weight |
controlled sodium content diet (2 %) (for 24 days) |
Rapp JP, et al., Genomics 1998 Jul 15;51(2):191-6 |
heart mass |
male |
62 days
| 20 |
|
|
1.25 |
g |
0.01 |
0.06 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
65835 |
633 |
SS.SR-(D7Rat16-D7Rat189)/Jr |
heart wet weight |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) |
Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. |
heart mass |
male |
68 days-70 days |
20 |
|
|
1.18 |
g |
0.02 |
0.07 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
11804 |
147 |
SHR/N |
heart left ventricle wet weight |
control condition |
Innes BA, et al., Hypertension 1998 Mar;31(3):741-6 |
heart left ventricle mass |
male |
140 days
| 34 |
|
|
1.02 |
g |
0.01 |
0.06 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
11664 |
113 |
F344/NHsd |
heart left ventricle wet weight |
control condition |
Zhao L et al., 2001, Circulation, 103(3), 442-7 |
heart left ventricle mass |
male |
105 days
| 12 |
|
median |
0.54 |
g |
|
|
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
11564 |
102 |
DRY |
heart left ventricle weight to body weight ratio |
control condition |
Innes BA, et al., Hypertension 1998 Mar;31(3):741-6 |
heart left ventricle mass |
male |
140 days
| 35 |
|
|
1.82 |
mg/g |
0.01 |
0.06 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
11667 |
113 |
SS/Jr |
heart wet weight |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) |
Saad Y, et al., Hypertension. 2007 |
heart mass |
male |
64 days-66 days |
0 |
|
|
1.31 |
g |
0.01 |
|
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
11982 |
205 |
SS/Jr |
heart weight to body weight ratio |
controlled sodium content diet (2 %) (between 24 and 27 days) |
Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85 |
heart mass |
male |
64 days-69 days |
20 |
|
|
4.39 |
g/kg |
0.05 |
0.24 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
11987 |
221 |
SS/Jr |
heart weight to body weight ratio |
controlled sodium content diet (2 %) (between 24 and 27 days) |
Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85 |
heart mass |
male |
64 days-69 days |
20 |
|
|
4.35 |
g/kg |
0.07 |
0.3 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
11988 |
221 |
SS/Jr |
heart weight to body weight ratio |
controlled sodium content diet (2 %) (between 24 and 27 days) |
Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85 |
heart mass |
male |
64 days-69 days |
20 |
|
|
4.22 |
g/kg |
0.06 |
0.29 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
11993 |
221 |
SS/Jr |
heart weight to body weight ratio |
controlled sodium content diet (2 %) (between 24 and 27 days) |
Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85 |
heart mass |
male |
64 days-69 days |
20 |
|
|
4.09 |
g/kg |
0.03 |
0.14 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
11994 |
221 |
SS/Jr |
heart weight to body weight ratio |
controlled sodium content diet (2 %) (between 24 and 27 days) |
Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85 |
heart mass |
male |
64 days-69 days |
20 |
|
|
4.08 |
g/kg |
0.04 |
0.17 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
11998 |
221 |
SS/Jr |
heart weight to body weight ratio |
controlled sodium content diet (2 %) (between 24 and 27 days) |
Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85 |
heart mass |
male |
64 days-69 days |
20 |
|
|
4.3 |
g/kg |
0.09 |
0.42 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
11999 |
221 |
SS/Jr |
heart weight to body weight ratio |
controlled sodium content diet (2 %) (between 24 and 27 days) |
Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85 |
heart mass |
male |
64 days-69 days |
20 |
|
|
4.42 |
g/kg |
0.06 |
0.27 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
12001 |
221 |
F344.OLETF-(D1Rat166-D1Rat90)/Tj |
mesenteric fat pad weight |
control condition |
Muramatsu Y, et al., Biochem Biophys Res Commun 2005 Jun 17;331(4):1270-6. |
mesenteric fat pad mass |
male |
245 days
| 9 |
|
|
14.8 |
g |
0.5 |
1.5 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
12443 |
262 |
SS.LEW-(D1Uia2-D1Rat49)/Jr |
heart weight to body weight ratio |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) |
Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. |
heart mass |
male |
68 days-70 days |
20 |
|
|
3.94 |
g/kg |
0.03 |
0.14 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
12563 |
266 |
WKY |
heart weight to body weight ratio |
controlled sodium content diet (0.4 %) (for 122 days) then controlled sodium content diet (1.4 %) (for 210 days) |
Inomata H, et al., Hypertens Res 2005 Mar;28(3):273-81. |
heart mass |
male |
360 days
| 4 |
|
|
2.5 |
g/kg |
0.1 |
0.2 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
12593 |
268 |
SS/Jr |
heart wet weight |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) |
Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. |
heart mass |
male |
64 days-66 days |
30 |
|
|
1.3 |
g |
0.01 |
0.07 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
12846 |
313 |
SS.LEW-(D1Mco85-D1Rat49)/Mco |
heart wet weight |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) |
Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. |
heart mass |
male |
64 days-66 days |
20 |
|
|
1.21 |
g |
0.14 |
0.61 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
12858 |
313 |
SS/Jr |
heart wet weight |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) |
Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. |
heart mass |
male |
68 days-70 days |
20 |
|
|
1.28 |
g |
0.02 |
0.07 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
12518 |
266 |
SS/Jr |
heart wet weight |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) |
Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. |
heart mass |
male |
68 days-70 days |
20 |
|
|
1.29 |
g |
0.02 |
0.08 |
post excision weight measurement |
|
|
|
0 |
|
|
regression of heart weight on body weight |
|
|
12522 |
266 |
SS.LEW-(D1Mco87-D1Rat71)/Jr |
heart wet weight |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) |
Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. |
heart mass |
male |
68 days-70 days |
20 |
|
|
1.29 |
g |
0.02 |
0.08 |
post excision weight measurement |
|
|
|
0 |
|
|
regression of heart weight on body weight |
|
|
12526 |
266 |
SS.LEW-(D1Uia2-D1Rat49)/Jr |
heart wet weight |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) |
Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. |
heart mass |
male |
68 days-70 days |
20 |
|
|
1.21 |
g |
0.02 |
0.09 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
12530 |
266 |
SS.LEW-(D1Rat196-D1Mco36)/Jr |
heart wet weight |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) |
Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. |
heart mass |
male |
68 days-70 days |
20 |
|
|
1.17 |
g |
0.01 |
0.03 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
12533 |
266 |
SS.LEW-(D1Uia8-D1Rat18)/Mco |
heart wet weight |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) |
Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. |
heart mass |
male |
68 days-70 days |
20 |
|
|
1.19 |
g |
0.01 |
0.06 |
post excision weight measurement |
|
|
|
0 |
|
|
regression of heart weight on body weight |
|
|
12535 |
266 |
SS/Jr |
heart weight to body weight ratio |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) |
Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. |
heart mass |
male |
68 days-70 days |
20 |
|
|
4.21 |
g/kg |
0.06 |
0.27 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
12547 |
266 |
SS.LEW-(D1Mco2-D1Rat49)/Jr |
heart weight to body weight ratio |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) |
Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. |
heart mass |
male |
68 days-70 days |
20 |
|
|
3.87 |
g/kg |
0.02 |
0.1 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
12557 |
266 |
SHRSP |
heart wet weight |
controlled sodium content diet (0.4 %) (for 122 days) then controlled sodium content diet (1.4 %) (for 210 days) |
Inomata H, et al., Hypertens Res 2005 Mar;28(3):273-81. |
heart mass |
female |
360 days
| 4 |
|
|
0.78 |
g |
0.05 |
0.1 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
12568 |
268 |
SS.LEW-(D1Uia8-D1Rat213)/Mco |
heart weight to body weight ratio |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) |
Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. |
heart mass |
male |
68 days-70 days |
20 |
|
|
3.45 |
g/kg |
0.06 |
0.26 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
12570 |
266 |
SHRSP |
heart weight to body weight ratio |
controlled sodium content diet (0.4 %) (for 122 days) then controlled sodium content diet (1.4 %) (for 210 days) |
Inomata H, et al., Hypertens Res 2005 Mar;28(3):273-81. |
heart mass |
female |
360 days
| 4 |
|
|
4.8 |
g/kg |
0.5 |
1.0 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
12571 |
268 |
LEW/OlaHsd |
liver weight to body weight ratio |
controlled olive oil content diet (5 %) (for 30 days) and controlled cholesterol content diet (2 %) (for 30 days) |
de Wolf ID, et al., Exp Biol Med (Maywood) 2002 Jul;227(7):529-34. |
liver mass |
female |
77 days
| 4 |
|
|
36.3 |
g/kg |
0.35 |
0.7 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
12581 |
267 |
WKY/N |
heart left ventricle wet weight |
control condition |
Ye P and West MJ, Clin Exp Pharmacol Physiol 2003 Dec;30(12):930-6. |
heart left ventricle mass |
female |
84 days
| 22 |
|
|
0.59 |
g |
0.05 |
0.24 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
13072 |
327 |
SS.SR-(D3Mco19-D3Mco5)/Jr |
heart wet weight |
controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (for 28 days) |
Cicila GT, et al., Mamm Genome 1999 Feb;10(2):112-6. |
heart mass |
male |
65 days
| 19 |
|
|
1.23 |
g |
0.01 |
0.03 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
11778 |
145 |
SS.SR-(Cyp11b1)/Jr |
heart wet weight |
controlled sodium content diet (1 %) (for 30 days) then controlled sodium content diet (0.2 %) (for 40 days) |
Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. |
heart mass |
male |
100 days
| 16 |
|
|
1.11 |
g |
0.02 |
0.07 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
11784 |
146 |
SS/Jr |
heart weight to body weight ratio |
controlled sodium content diet (2 %) (between 25 and 28 days) |
Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35. |
heart mass |
not specified |
64 days-68 days |
41 |
|
|
4.06 |
g/kg |
0.04 |
0.26 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
11843 |
148 |
SS/Jr |
heart wet weight |
controlled sodium content diet (2 %) (for 24 days) |
Saad Y, et al., Mamm Genome. 2008 Jan 4 |
heart mass |
male |
64 days-68 days |
20 |
|
|
1.17 |
g |
0.01 |
0.04 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
12157 |
232 |
WKY/NCruk |
heart right ventricle wet weight |
control condition |
Sebkhi A, et al., Hypertension 1999 Apr;33(4):949-53. |
heart right ventricle mass |
not specified |
84 days
| 22 |
|
|
0.21 |
g |
0.0 |
0.02 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
12188 |
233 |
SS.MNS-(D10Mco30-D10Got101)/Mco |
heart wet weight |
controlled sodium content diet (2 %) (for 24 days) |
Saad Y, et al., Mamm Genome. 2008 Jan 4 |
heart mass |
male |
64 days-68 days |
20 |
|
|
1.16 |
g |
0.01 |
0.04 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
12207 |
232 |
SS.MNS-(D10Mco30-D10Got91)/3Mco |
heart wet weight |
controlled sodium content diet (2 %) (for 24 days) |
Saad Y, et al., Mamm Genome. 2008 Jan 4 |
heart mass |
male |
64 days-68 days |
20 |
|
|
1.13 |
g |
0.01 |
0.04 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
12210 |
232 |
SS.MNS-(D10Mco62-D10Got99)/Mco |
heart weight to body weight ratio |
controlled sodium content diet (2 %) (for 24 days) |
Saad Y, et al., Mamm Genome. 2008 Jan 4 |
heart mass |
male |
64 days-68 days |
20 |
|
|
4.09 |
g/kg |
0.03 |
0.13 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
12221 |
232 |
SS/Jr |
heart wet weight |
controlled sodium content diet (2 %) (for 28 days) |
Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. |
heart mass |
male |
68 days-70 days |
20 |
|
|
1.3 |
g |
0.01 |
0.05 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
12960 |
305 |
SS/Jr |
both kidneys wet weight |
controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) |
Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. |
kidney mass |
male |
70 days-72 days |
20 |
|
|
2.9 |
g |
0.05 |
0.23 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
12316 |
237 |
SHR/NHsd |
heart wet weight |
controlled sodium content diet (0.3 %) |
Packard M, et al., Am J Physiol Renal Physiol. 2009 Apr;296(4):F839-46. Epub 2009 Jan 28. |
heart mass |
male |
84 days
| 12 |
|
|
1.08 |
g |
0.01 |
0.04 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
12349 |
246 |
SS.LEW-(D10Mco113-D10Got93)/Mco |
heart weight to body weight ratio |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) |
Saad Y, et al., Hypertension. 2007 |
heart mass |
male |
64 days-66 days |
0 |
|
|
3.91 |
g/kg |
0.04 |
|
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
12050 |
205 |
SS.WKY-(D2N35-Mme)/Mco |
heart weight to body weight ratio |
controlled sodium content diet (2 %) (for 28 days) |
Deng AY, et al., Hypertension 1997 Aug;30(2 Pt 1):199-202 |
heart mass |
male |
68 days
| 27 |
|
|
3.28 |
g/kg |
0.02 |
0.09 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
|
12101 |
231 |
SS.LEW-(D17Rat65-D17Chm2)/Ayd |
heart weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
heart mass |
male |
98 days
| 5 |
|
|
3.6 |
g/kg |
0.2 |
0.45 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
12118 |
226 |
SS/HsdMcwiCrl |
both kidneys wet weight to tibia length ratio |
controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) then controlled protein content diet (19 %) (for 91 days) |
Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26. |
kidney mass |
male |
112 days
| 6 |
|
|
0.71 |
g/cm |
0.03 |
0.07 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
67642 |
735 |
SS/HsdMcwiCrl |
epididymal fat pad weight to tibia length ratio |
controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) |
Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26. |
epididymal fat pad mass |
male |
112 days
| 9 |
|
|
1.33 |
g/cm |
0.07 |
0.21 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
67653 |
735 |
SS/Jr |
calculated heart weight |
controlled sodium content diet (2 %) (between 24 and 27 days) |
Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 |
heart mass |
not specified |
64 days-71 days |
40 |
regression of heart weight on body weight |
|
1.18 |
g |
0.01 |
0.06 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
4 rats per cage, 2 SR/Jr 2 LEW/NCrl |
64766 |
222 |
SS.LEW-(D18Rat30-D18Chm29)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98 days
| 8 |
|
|
10.4 |
g/kg |
0.2 |
0.57 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
64801 |
226 |
SS.LEW-(D3Rat52-D3Chm57)/Ayd |
heart left ventricle wet weight |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) |
Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. |
heart left ventricle mass |
male |
77 days
| 8 |
|
|
0.79 |
g |
0.03 |
0.09 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
65034 |
542 |
ACI/SegHsd |
spleen wet weight |
control condition |
Yamashita S, et al., Cancer Res 2005 Apr 1;65(7):2610-6. |
spleen mass |
male |
900 days
| 12 |
|
null |
0.8 |
g |
|
|
post excision weight measurement |
|
|
|
0 |
|
method not specified, assumed to be digital scale |
|
|
|
13305 |
341 |
SS/Jr |
heart wet weight |
controlled sodium content diet (2 %) (between 24 and 27 days) |
Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 |
heart mass |
not specified |
64 days-71 days |
20 |
|
|
1.21 |
g |
0.02 |
0.07 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
4 rats per cage, 2 SR/Jr 2 LEW/NCrl |
64762 |
222 |
SS.SHR-(D9Rat7-D9Rat52)/Mco |
heart wet weight |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) |
Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. |
heart mass |
not specified |
0 days
| 0 |
|
|
1.5 |
g |
0.02 |
|
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
67561 |
749 |
SS/Jr |
heart weight to body weight ratio |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) |
Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. |
heart mass |
not specified |
0 days
| 0 |
|
|
4.16 |
g/kg |
0.07 |
|
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
67566 |
749 |
SS.SHR-(D9Rat7-D9Mco91)/Mco |
heart weight to body weight ratio |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) |
Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. |
heart mass |
not specified |
0 days
| 0 |
|
|
4.16 |
g/kg |
0.06 |
|
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
67576 |
749 |
LEW/Cub |
heart weight to body weight ratio |
losartan (10 mg/kg) (for 0.2 hours) then pentolinium (5 mg/kg) (for 0.1 hours) then NG-nitroarginine methyl ester (30 mg/kg) (for 0.3 hours) |
Ueno T, et al., Physiol Res 2003;52(6):689-700. |
heart mass |
not specified |
0 days
| 9 |
|
|
2.5 |
g/kg |
|
|
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
65413 |
568 |
SS/Jr |
calculated kidney weight |
control condition |
Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87 |
kidney mass |
male |
183 days
| 6 |
adjusted organ weight for differences in body weight by regression analysis using programs from SPSS |
|
3.31 |
g |
0.14 |
0.34 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
65450 |
104 |
SHR/FubRkb |
heart weight to body weight ratio |
control condition |
Schulz A, et al., J Am Soc Nephrol. 2007 Jan;18(1):113-21 |
heart mass |
not specified |
168 days
| 10 |
|
|
2.93 |
g/kg |
0.03 |
0.09 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
65370 |
117 |
MWF/FubRkb |
heart weight to body weight ratio |
control condition |
Schulz A, et al., J Am Soc Nephrol. 2007 Jan;18(1):113-21 |
heart mass |
not specified |
168 days
| 18 |
|
|
2.3 |
g/kg |
0.04 |
0.17 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
65372 |
117 |
SS/Jr |
heart wet weight |
controlled sodium content diet (2 %) (between 24 and 27 days) |
Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 |
heart mass |
not specified |
64 days-71 days |
40 |
|
|
1.24 |
g |
0.01 |
0.05 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
4 rats per cage, 2 SR/Jr 2 LEW/NCrl |
64747 |
222 |
SHRSP/Izm |
retroperitoneal fat pad weight to body weight ratio |
control condition (0 null) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
retroperitoneal fat pad mass |
female |
91 days
| 5 |
|
|
0.67 |
% |
0.03 |
0.08 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
64845 |
115 |
SHRSP.WKY-(Klk1-D1Rat116)/Izm |
retroperitoneal fat pad weight to body weight ratio |
control condition (0 null) |
Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. |
retroperitoneal fat pad mass |
female |
91 days
| 5 |
|
|
0.56 |
% |
0.04 |
0.09 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
64846 |
115 |
SHR/NHsd |
calculated heart weight |
control condition |
Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87 |
heart mass |
male |
183 days
| 6 |
adjusted heart weight for differences in body weight by regression analysis using programs from SPSS |
|
1.63 |
g |
0.01 |
0.03 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
65449 |
104 |
ACI/N |
both adrenal glands wet weight |
control condition |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
adrenal gland mass |
both |
167 days-174 days |
210 |
|
|
36.0 |
mg |
0.27 |
3.9 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
65987 |
114 |
BN/SsN |
both adrenal glands weight to body weight ratio |
control condition |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
adrenal gland mass |
both |
167 days-174 days |
210 |
|
|
25.1 |
mg/100g |
0.16 |
2.3 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
65992 |
114 |
F344/NRrrc |
both adrenal glands weight to body weight ratio |
control condition |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
adrenal gland mass |
both |
167 days-174 days |
210 |
|
|
21.1 |
mg/100g |
0.09 |
1.3 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
65996 |
114 |
WKY/N |
heart weight to body weight ratio |
control condition |
Johannesson M, et al., Genome Res. 2009 Jan;19(1):150-8 |
heart mass |
both |
167 days-174 days |
45 |
|
|
3.96 |
g/kg |
0.04 |
0.25 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
66000 |
114 |
SS/Jr |
heart weight to body weight ratio |
controlled sodium content diet (0.2 %) (for 10 days) then controlled sodium content diet (2 %) (for 24 days) |
Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 |
heart mass |
not specified |
68 days
| 27 |
|
|
4.05 |
g/kg |
|
|
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
66031 |
650 |
SS-Mmp2em1Mcwi-/- |
right kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
6 |
|
|
1.4 |
g |
0.08 |
0.21 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66204 |
717 |
SS-Alms1em1Mcwi-/- |
right kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
6 |
|
|
1.3 |
g |
0.09 |
0.23 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66205 |
717 |
SS-Chr 5BN-Cyp4a2em1Mcwi+/+ |
right kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
3 |
|
|
1.77 |
g |
0.07 |
0.13 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66224 |
717 |
SS-Cybaem1Mcwi-/- |
right kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
6 |
|
|
1.44 |
g |
0.06 |
0.15 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66227 |
717 |
SS-Gpr183em1Mcwi+/+ |
right kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
4 |
|
|
1.45 |
g |
0.07 |
0.13 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66228 |
717 |
SS-Gpr183em3Mcwi+/+ |
right kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
4 |
|
|
1.55 |
g |
0.05 |
0.09 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66233 |
717 |
SS-Nox4em2Mcwi+/+ |
right kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
3 |
|
|
1.28 |
g |
0.08 |
0.13 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66235 |
717 |
SS-Mmp2em2Mcwi-/- |
right kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
6 |
|
|
1.36 |
g |
0.06 |
0.14 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66238 |
717 |
SS-Renem1Mcwi+/+ |
right kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
4 |
|
|
1.52 |
g |
0.06 |
0.11 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66246 |
717 |
SS-Bcas3em4Mcwi+/+ |
right kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
1 |
|
|
1.38 |
g |
|
|
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
66248 |
717 |
SS-Nckap5em2Mcwi-/- |
heart wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
heart mass |
male |
70 days-77 days |
8 |
|
|
1.14 |
g |
0.04 |
0.1 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
67011 |
717 |
SS-Ncf2em1Mcwi+/+ |
heart wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
heart mass |
male |
70 days-77 days |
5 |
|
|
1.16 |
g |
0.06 |
0.13 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
67013 |
717 |
LEW/Rkb |
both kidneys wet weight to body weight ratio |
control condition |
Schulz A, et al., J Am Soc Nephrol 2002 Nov;13(11):2706-14. |
kidney mass |
not specified |
126 days
| 8 |
|
|
5.93 |
g/kg |
0.53 |
1.5 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
67598 |
769 |
SHRSP/Gcrc |
heart weight to body weight ratio |
control condition |
Jeffs B, et al., Hypertension 2000 Jan;35(1 Pt 2):179-87. |
heart mass |
male |
147 days
| 3 |
|
|
4.5 |
g/kg |
0.3 |
0.52 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
65535 |
613 |
SS-Adra2aem1Mcwi-/- |
left kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
9 |
|
|
1.36 |
g |
0.04 |
0.13 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
43631 |
421 |
SS-Rasgrp3em1Mcwi+/+ |
left kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
6 |
|
|
1.53 |
g |
0.07 |
0.16 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
43632 |
421 |
SS-Rasgrp3em1Mcwi-/- |
left kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
10 |
|
|
1.58 |
g |
0.04 |
0.14 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
43633 |
421 |
SS-Ulk3em4Mcwi+/+ |
left kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
2 |
|
|
1.49 |
g |
0.17 |
0.24 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
43635 |
421 |
SS-Adra2aem1Mcwi-/- |
heart wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
heart mass |
male |
70 days-77 days |
9 |
|
|
1.07 |
g |
0.02 |
0.06 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
43645 |
421 |
SS-Ulk3em4Mcwi+/+ |
heart wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
heart mass |
male |
70 days-77 days |
2 |
|
|
1.16 |
g |
0.07 |
0.1 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
43649 |
421 |
SS-Ulk3em4Mcwi-/+ |
heart wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
heart mass |
male |
70 days-77 days |
4 |
|
|
1.18 |
g |
0.17 |
0.33 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
43652 |
421 |
SS-Wdr72em2Mcwi+/+ |
right kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
7 |
|
|
1.42 |
g |
0.05 |
0.12 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
43604 |
421 |
SS-Agtrapem4Mcwi-/- |
right kidney wet weight |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
kidney mass |
male |
70 days-77 days |
7 |
|
|
1.43 |
g |
0.03 |
0.09 |
post excision weight measurement |
|
|
|
0 |
|
|
|
|
- |
43610 |
421 |
LEW |
heart left ventricle wet weight |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) |
Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. |
heart left ventricle mass |
male |
77 days
| 14 |
|
|
0.72 |
g |
0.03 |
0.13 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
65027 |
542 |
SS.SR-(D7Mco19-D7Mco7)/Jr |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
kidney mass |
male |
114 days-118 days |
3 |
|
|
10.53 |
g/kg |
0.18 |
0.31 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
65127 |
283 |
SS.SR-(D3Arb14-D3Mco36)/Mco |
heart wet weight |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 0 and 672 hours) then controlled sodium content diet (4 %) (between 46 and 48 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
heart mass |
male |
114 days-118 days |
6 |
|
|
1.67 |
g |
0.05 |
0.12 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
65130 |
283 |
SS.SR-(D7Mco19-D7Mco7)/Jr |
heart wet weight |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 0 and 672 hours) then controlled sodium content diet (4 %) (between 46 and 48 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
heart mass |
male |
114 days-118 days |
3 |
|
|
1.82 |
g |
0.07 |
0.12 |
post excision weight measurement |
|
0 |
|
0 |
|
|
|
|
|
65132 |
283 |
GH/Omr |
heart left ventricle wet weight |
angiotensin II (5-50 ng/kg/min) (between 0.2 and 1 hours) then norepinephrine (0.1-1 ug/kg/min) (between 0.2 and 1 hours) then phenylephrine (4 ug/kg) (between 0 and 0 hours) |
Bilusic M, et al., Croat Med J. 2008 Oct;49(5):586-99. |
heart left ventricle mass |
male |
132 days-146 days |
21 |
|
|
1.69 |
g |
0.03 |
0.13 |
post excision weight measurement |
|
0.0 |
|
0 |
|
ng/kg/min |
|
|
|
68329 |
101 |
BN/Elh |
heart left ventricle wet weight |
angiotensin II (5-50 ng/kg/min) (between 0.2 and 1 hours) then norepinephrine (0.1-1 ug/kg/min) (between 0.2 and 1 hours) then phenylephrine (4 ug/kg) (between 0 and 0 hours) |
Bilusic M, et al., Croat Med J. 2008 Oct;49(5):586-99. |
heart left ventricle mass |
male |
132 days-146 days |
21 |
|
|
1.15 |
g |
0.03 |
0.13 |
post excision weight measurement |
|
0.0 |
|
0 |
|
ng/kg/min |
|
|
|
68333 |
101 |
GH/Omr |
heart left ventricle weight to body weight ratio |
angiotensin II (5-50 ng/kg/min) (between 0.2 and 1 hours) then norepinephrine (0.1-1 ug/kg/min) (between 0.2 and 1 hours) then phenylephrine (4 ug/kg) (between 0 and 0 hours) |
Bilusic M, et al., Croat Med J. 2008 Oct;49(5):586-99. |
heart left ventricle mass |
male |
132 days-146 days |
21 |
|
|
4.7 |
mg/g |
0.15 |
0.7 |
post excision weight measurement |
|
0.0 |
|
0 |
|
ng/kg/min |
Original CMO ID was CMO:0000540. Corrected 2-15-2018. |
|
|
68334 |
101 |
WAG/RijKyo |
heart wet weight |
control condition |
Redina OE, et al., Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):456-64. |
heart mass |
not specified |
180 days
| 9 |
|
|
1.01 |
g |
0.03 |
0.09 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
68048 |
835 |
WAG/RijKyo |
heart weight to body weight ratio |
control condition |
Redina OE, et al., Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):456-64. |
heart mass |
not specified |
180 days
| 9 |
|
|
3.27 |
g/kg |
0.09 |
0.27 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
68055 |
835 |
WAG/RijKyo |
both kidneys wet weight to body weight ratio |
control condition |
Redina OE, et al., Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):456-64. |
kidney mass |
not specified |
180 days
| 9 |
|
|
5.2 |
g/kg |
0.1 |
0.3 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
68057 |
835 |
WAG/RijKyo |
both adrenal glands weight to body weight ratio |
control condition |
Redina OE, et al., Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):456-64. |
adrenal gland mass |
not specified |
180 days
| 9 |
|
|
14.0 |
mg/100g |
0.3 |
0.9 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
68060 |
835 |
SS/JrTol |
heart wet weight |
control condition (for 140 days) |
Garrett MR, et al., Physiol Genomics. 2007 May 15;. |
heart mass |
male |
140 days
| 6 |
|
|
1.3 |
g |
0.02 |
0.05 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
67962 |
834 |
PD/Cub |
single kidney wet weight to body weight ratio |
controlled sucrose content diet (for 7 days) then dexamethasone (0.03 mg/ml) (for 3 days) |
Seda O, et al., Physiol Genomics. 2005 Apr 14;21(2):243-52. Epub 2005 Feb 22. |
kidney mass |
male |
310 days
| 6 |
|
|
3.8 |
g/kg |
0.04 |
0.1 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
70286 |
1318 |
WKY/NCruk |
left kidney wet weight |
left nephrectomy and left kidney transplant then right nephrectomy |
Clemitson JR, et al., Hypertension 2002 Sep;40(3):292-7 |
kidney mass |
male |
175 days
| 17 |
|
|
1.54 |
g |
0.06 |
0.23 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
67750 |
110 |
COP.DA-(D16Rat12-D16Rat90)/Mco |
pancreas wet weight |
control condition |
Ways JA, et al., Physiol Genomics. 2006 Dec 19;. |
pancreas mass |
not specified |
105 days
| 8 |
|
|
0.49 |
g |
0.04 |
0.11 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
68491 |
933 |
COP.DA-(D3Rat233-D3Mgh14)/Mco |
pancreas wet weight |
control condition |
Ways JA, et al., Physiol Genomics. 2006 Dec 19;. |
pancreas mass |
not specified |
105 days
| 18 |
|
|
0.52 |
g |
0.02 |
0.08 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
68492 |
933 |
COP.DA-(D3Rat233-D3Mgh14)/Mco |
heart wet weight |
control condition |
Ways JA, et al., Physiol Genomics. 2006 Dec 19;. |
heart mass |
not specified |
105 days
| 18 |
|
|
0.75 |
g |
0.02 |
0.08 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
68508 |
933 |
COP.DA-(D16Rat12-D16Rat90)/Mco |
pancreas weight to body weight ratio |
control condition |
Ways JA, et al., Physiol Genomics. 2006 Dec 19;. |
pancreas mass |
not specified |
105 days
| 8 |
|
|
1.79 |
mg/g |
0.12 |
0.34 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
68511 |
933 |
COP.DA-(D16Rat12-D16Rat90)/Mco |
liver weight to body weight ratio |
control condition |
Ways JA, et al., Physiol Genomics. 2006 Dec 19;. |
liver mass |
not specified |
105 days
| 8 |
|
|
34.2 |
g/kg |
0.67 |
1.9 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
68515 |
933 |
COP/OlaHsd |
heart left ventricle weight to body weight ratio |
control condition |
Ways JA, et al., Physiol Genomics. 2006 Dec 19;. |
heart left ventricle mass |
not specified |
105 days
| 15 |
|
|
1.75 |
mg/g |
0.02 |
0.08 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
68517 |
933 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
heart weight to body weight ratio |
cold ambient air exposure (4 degrees C) (for 90 days) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
heart mass |
not specified |
112 days
| 10 |
|
|
3.18 |
g/kg |
0.07 |
0.22 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
68697 |
971 |
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
both kidneys wet weight |
cold ambient air exposure (4 degrees C) (for 90 days) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
kidney mass |
not specified |
112 days
| 10 |
|
|
3.32 |
g |
0.07 |
0.23 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
68700 |
971 |
Hsd:WI |
spleen wet weight |
vehicle control condition (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
spleen mass |
male |
119 days-126 days |
5 |
|
|
0.71 |
g |
0.03 |
0.07 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
76115 |
1545 |
Hsd:WI |
spleen wet weight |
bisphenol A (250 mg/kg/d) (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
spleen mass |
male |
119 days-126 days |
6 |
|
|
0.7 |
g |
0.14 |
0.35 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
76117 |
1545 |
ACI/SegHsd |
thymus wet weight |
diethylstilbestrol (5 mg) (for 84 days) and surgical implantation |
Gould KA, et al., Mamm Genome. 2006 May;17(5):451-64. |
thymus mass |
male |
147 days
| 13 |
|
|
166.0 |
mg |
6.1 |
22.0 |
post excision weight measurement |
|
0.0 |
subcutaneous implant |
84 |
days |
diethylstilbestrol |
|
|
|
69099 |
1121 |
SS-Rag1em2Mcwi |
thymus wet weight |
controlled sodium content diet (4 %) (for 21 days) |
Mattson DL, et al., Am J Physiol Regul Integr Comp Physiol. 2013 Jan 30. |
thymus mass |
not specified |
84 days
| 4 |
|
|
120.0 |
mg |
10.0 |
20.0 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
69290 |
1057 |
HanTac:WH |
thyroid gland wet weight |
bisphenol A (0.025 mg/kg/d) (between 16 and 17 days) |
Christiansen S, et al., Reproduction. 2014 Mar 2;147(4):477-87. doi: 10.1530/REP-13-0377. Print 2014. |
thyroid gland mass |
female |
16 days-17 days |
20 |
|
|
5.2 |
mg |
0.27 |
1.2 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
96708 |
1559 |
SD |
liver wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
male |
71 days-85 days |
6 |
|
|
4.31 |
g |
0.14 |
0.35 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
85192 |
1602 |
SD |
heart wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
female |
71 days-85 days |
6 |
|
|
0.41 |
g |
0.02 |
0.04 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
85237 |
1602 |
SD |
heart wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
female |
85 days-99 days |
6 |
|
|
0.44 |
g |
0.01 |
0.03 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
85240 |
1602 |
SD |
spleen wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
female |
85 days-99 days |
6 |
|
|
0.23 |
g |
0.0 |
0.01 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
85253 |
1602 |
SD |
brain wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
male |
85 days-99 days |
6 |
|
|
0.68 |
g |
0.01 |
0.03 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
85259 |
1602 |
SD |
adrenal gland wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
male |
71 days-85 days |
6 |
|
|
0.02 |
g |
0.0 |
0.0 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
85266 |
1602 |
SD |
adrenal gland wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
male |
85 days-99 days |
6 |
|
|
0.02 |
g |
0.0 |
0.0 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
85270 |
1602 |
SD |
testis wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
testis mass |
male |
71 days-85 days |
6 |
|
|
1.17 |
g |
0.05 |
0.13 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
85280 |
1602 |
FHH.PCK-(D9Rat35-D9Rat70)/Mcwi |
both kidneys wet weight |
control condition |
O'Meara CC, et al., Physiol Genomics. 2012 Aug 1;44(15):741-53. doi: 10.1152/physiolgenomics.00187.2011. Epub 2012 Jun 5. |
kidney mass |
male |
189 days
| 15 |
|
|
2.12 |
g |
0.2 |
0.77 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
96908 |
1738 |
Crl:SD |
left renal fat pad weight |
controlled ethanol content drinking water (1 %) (for 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
renal fat pad mass |
female |
105 days
| 12 |
|
|
0.74 |
g |
0.04 |
0.15 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
total body fat volume, cm3 |
|
|
75837 |
1538 |
Crl:SD |
left renal fat pad weight to body weight ratio |
controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
renal fat pad mass |
female |
105 days
| 12 |
|
|
0.5 |
% |
0.04 |
0.13 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
total body fat volume, cm3 |
|
|
75846 |
1538 |
Hsd:WI |
spleen weight to body weight ratio |
bisphenol A (125 mg/kg/d) (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
spleen mass |
male |
119 days-126 days |
6 |
|
|
0.18 |
% |
0.0 |
0.01 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
76121 |
1545 |
Hsd:WI |
spleen weight to body weight ratio |
bisphenol A (250 mg/kg/d) (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
spleen mass |
male |
119 days-126 days |
6 |
|
|
0.2 |
% |
0.03 |
0.08 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
76122 |
1545 |
BluHsd:LE |
both testes wet weight |
bisphenol A (25 ug/kg) (for 30 days) and controlled in utero environment (for 9 days) then maternal milk (for 21 days) then controlled fat content diet (21.2 %) (for 28 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
testis mass |
male |
98 days
| 8 |
|
|
3.5 |
g |
0.3 |
0.85 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
76251 |
1543 |
Hsd:WI |
left kidney wet weight to body weight ratio |
octylphenol (125 mg/kg/d) (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
kidney mass |
male |
119 days-126 days |
6 |
|
|
3.65 |
mg/g |
0.19 |
0.47 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
76088 |
1545 |
Hsd:WI |
right kidney wet weight |
octylphenol (250 mg/kg/d) (for 91 days) |
Yildiz N and Barlas N, Hum Exp Toxicol. 2013 Jul;32(7):675-86. doi: 10.1177/0960327112464796. |
kidney mass |
male |
119 days-126 days |
6 |
|
|
1.09 |
g |
0.07 |
0.16 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
76074 |
1545 |
BluHsd:LE |
both testes wet weight |
bisphenol A (25 ug/kg) (for 30 days) and controlled in utero environment (for 9 days) then maternal milk (for 21 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
testis mass |
male |
98 days
| 8 |
|
|
3.6 |
g |
0.2 |
0.57 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
76248 |
1543 |
HanTac:WH |
combined levator ani and bulbocavernosus muscle weight |
vehicle control condition (between 16 and 17 days) |
Christiansen S, et al., Reproduction. 2014 Mar 2;147(4):477-87. doi: 10.1530/REP-13-0377. Print 2014. |
skeletal muscle mass |
male |
16 days-17 days |
18 |
|
|
26.0 |
mg |
1.04 |
4.4 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
96662 |
1559 |
HanTac:WH |
liver wet weight |
vehicle control condition (between 16 and 17 days) |
Christiansen S, et al., Reproduction. 2014 Mar 2;147(4):477-87. doi: 10.1530/REP-13-0377. Print 2014. |
liver mass |
male |
16 days-17 days |
18 |
|
|
0.75 |
g |
0.03 |
0.11 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
96672 |
1559 |
HanTac:WH |
liver wet weight |
bisphenol A (0.25 mg/kg/d) (between 16 and 17 days) |
Christiansen S, et al., Reproduction. 2014 Mar 2;147(4):477-87. doi: 10.1530/REP-13-0377. Print 2014. |
liver mass |
male |
16 days-17 days |
14 |
|
|
0.72 |
g |
0.02 |
0.07 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
96674 |
1559 |
HanTac:WH |
liver wet weight |
bisphenol A (5 mg/kg/d) (between 16 and 17 days) |
Christiansen S, et al., Reproduction. 2014 Mar 2;147(4):477-87. doi: 10.1530/REP-13-0377. Print 2014. |
liver mass |
male |
16 days-17 days |
16 |
|
|
0.74 |
g |
0.02 |
0.08 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
96675 |
1559 |
HanTac:WH |
both adrenal glands wet weight |
bisphenol A (0.25 mg/kg/d) (between 16 and 17 days) |
Christiansen S, et al., Reproduction. 2014 Mar 2;147(4):477-87. doi: 10.1530/REP-13-0377. Print 2014. |
adrenal gland mass |
male |
16 days-17 days |
14 |
|
|
7.2 |
mg |
0.4 |
1.5 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
96679 |
1559 |
HanTac:WH |
left ovary wet weight |
vehicle control condition (between 16 and 17 days) |
Christiansen S, et al., Reproduction. 2014 Mar 2;147(4):477-87. doi: 10.1530/REP-13-0377. Print 2014. |
ovary mass |
female |
16 days-17 days |
15 |
|
|
3.2 |
mg |
0.27 |
1.04 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
left ovary |
|
|
96697 |
1559 |
HanTac:WH |
bulbourethral gland wet weight |
bisphenol A (0.25 mg/kg/d) (between 16 and 17 days) |
Christiansen S, et al., Reproduction. 2014 Mar 2;147(4):477-87. doi: 10.1530/REP-13-0377. Print 2014. |
bulbourethral gland mass |
male |
16 days-17 days |
14 |
|
|
1.5 |
mg |
0.11 |
0.4 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
96669 |
1559 |
SD |
both lungs wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
male |
71 days-85 days |
6 |
|
|
0.77 |
g |
0.04 |
0.11 |
post excision weight measurement |
|
0.0 |
|
0 |
|
|
|
|
|
85221 |
1602 |
|