SS/JrHsdMcwi |
urine albumin excretion rate |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
urine albumin amount |
male |
87 days-120 days |
6 |
5.71 |
mg/d |
0.54 |
1.31 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
51455 |
481 |
FHH/EurMcwi |
urine albumin excretion rate |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
urine albumin amount |
female |
87 days-120 days |
7 |
1.37 |
mg/d |
0.31 |
0.81 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
Moms and pups used in studies were fed Teklad |
51465 |
481 |
SS-Chr 18BN/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
urine albumin amount |
female |
87 days-120 days |
8 |
2.78 |
mg/d |
0.7 |
1.97 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
Moms and pups used in studies were fed Teklad |
51469 |
481 |
SHR/NCrl |
urine albumin excretion rate |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
urine albumin amount |
male |
87 days-120 days |
9 |
0.75 |
mg/d |
0.12 |
0.36 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
Moms and pups used in studies were fed Teklad |
51471 |
481 |
BN/NHsdMcwi |
urine albumin excretion rate |
controlled sodium content diet (4 %) (between 17 and 36 days) |
PhysGen Renal A data |
urine albumin amount |
male |
87 days-120 days |
4 |
1.22 |
mg/d |
0.23 |
0.45 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
Moms and pups used in studies were fed Dyets |
51571 |
481 |
SHR/Fub |
urine albumin excretion rate |
controlled sodium content diet (0.2 %) |
Poyan Mehr A, et al., Physiol Genomics 2003 Aug 15;14(3):209-16. |
urine albumin amount |
not specified |
196 days
| 11 |
2.6 |
mg/d |
|
|
|
enzyme linked immunosorbent assay |
urine |
0.0 |
|
0 |
|
rat albumin ELISA |
|
|
13285 |
335 |
SS-Ets1em1Mcwi+/+ |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine albumin amount |
male |
70 days-77 days |
4 |
111.73 |
mg/d |
41.84 |
83.68 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
- |
66901 |
717 |
SS-Nox4em2Mcwi-/- |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine albumin amount |
male |
70 days-77 days |
5 |
17.0 |
mg/d |
2.3 |
5.13 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
- |
66914 |
717 |
SS-Itga9em1Mcwi+/+ |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine albumin amount |
male |
70 days-77 days |
4 |
34.92 |
mg/d |
4.36 |
8.71 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
- |
66923 |
717 |
SS-Nckap5em3Mcwi+/+ |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine albumin amount |
male |
70 days-77 days |
2 |
47.26 |
mg/d |
29.31 |
41.45 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
- |
66928 |
717 |
FHH-Chr 20BN/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
urine albumin amount |
male |
80 days-99 days |
8 |
138.32 |
mg/d |
33.41 |
94.5 |
Download Values
|
radioimmunoassay |
|
|
|
0 |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52401 |
482 |
FHH-Chr 2BN/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
urine albumin amount |
male |
80 days-99 days |
5 |
117.94 |
mg/d |
38.55 |
86.21 |
Download Values
|
radioimmunoassay |
|
|
|
0 |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52412 |
482 |
FHH-Chr 17BN/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
urine albumin amount |
male |
80 days-99 days |
10 |
151.8 |
mg/d |
21.71 |
68.65 |
Download Values
|
radioimmunoassay |
|
|
|
0 |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52417 |
482 |
FHH-Chr XBN/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
urine albumin amount |
male |
80 days-99 days |
7 |
204.89 |
mg/d |
18.57 |
49.14 |
Download Values
|
radioimmunoassay |
|
|
|
0 |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52421 |
482 |
FHH-Chr XBN/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
urine albumin amount |
female |
80 days-99 days |
7 |
54.12 |
mg/d |
21.95 |
58.07 |
Download Values
|
radioimmunoassay |
|
|
|
0 |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52428 |
482 |
FHH-Chr 9BN/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
urine albumin amount |
male |
80 days-99 days |
6 |
246.64 |
mg/d |
17.37 |
42.55 |
Download Values
|
radioimmunoassay |
|
|
|
0 |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52429 |
482 |
SS-Chr 4BN/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
urine albumin amount |
male |
80 days-99 days |
7 |
53.64 |
mg/d |
9.34 |
24.71 |
Download Values
|
radioimmunoassay |
|
|
|
0 |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52615 |
482 |
SS.BN-(D8Rat163-D8Rat81)/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
urine albumin amount |
male |
80 days-99 days |
21 |
21.33 |
mg/d |
6.67 |
30.55 |
Download Values
|
radioimmunoassay |
|
|
|
0 |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52623 |
482 |
SS-Chr 2BN/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (8 %) (between 19 and 22 days) |
PhysGen Renal B data |
urine albumin amount |
male |
80 days-99 days |
10 |
73.9 |
mg/d |
13.02 |
41.18 |
Download Values
|
radioimmunoassay |
|
|
|
0 |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52628 |
482 |
FHH-Chr 15BN/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
urine albumin amount |
male |
80 days-99 days |
9 |
73.05 |
mg/d |
23.6 |
70.81 |
Download Values
|
radioimmunoassay |
|
|
|
0 |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52387 |
482 |
FHH-Chr 19BN/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
urine albumin amount |
male |
80 days-99 days |
7 |
227.43 |
mg/d |
44.77 |
118.45 |
Download Values
|
radioimmunoassay |
|
|
|
0 |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52390 |
482 |
SS.BN-(D13Rat20-D13Rat127)/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (8 %) (for 18 days) |
Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. |
urine albumin amount |
female |
84 days-88 days |
12 |
21.2 |
mg/d |
4.9 |
16.97 |
|
urine analysis |
|
86400 |
|
0 |
|
|
|
|
65216 |
15 |
SS.BN-(D13Rat115-D13Rat61)/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (8 %) (for 18 days) |
Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. |
urine albumin amount |
male |
84 days-88 days |
12 |
45.4 |
mg/d |
6.5 |
22.52 |
|
urine analysis |
|
86400 |
|
0 |
|
|
|
|
65221 |
15 |
SS.BN-(D13Rat123-D13Rat197)/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (8 %) (for 18 days) |
Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. |
urine albumin amount |
male |
84 days-88 days |
12 |
56.8 |
mg/d |
9.2 |
31.87 |
|
urine analysis |
|
86400 |
|
0 |
|
|
|
|
65222 |
15 |
SS.BN-(D13Rat101-D13Rat46)/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (8 %) (for 18 days) |
Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. |
urine albumin amount |
female |
84 days-88 days |
12 |
29.2 |
mg/d |
5.4 |
18.71 |
|
urine analysis |
|
86400 |
|
0 |
|
|
|
|
65235 |
15 |
SS/Jr |
urine albumin excretion rate |
controlled sodium content diet (0.2 %) |
Poyan Mehr A, et al., Physiol Genomics 2003 Aug 15;14(3):209-16. |
urine albumin amount |
not specified |
196 days
| 12 |
148.47 |
mg/d |
|
|
|
enzyme linked immunosorbent assay |
urine |
0.0 |
|
0 |
|
rat albumin ELISA |
|
|
13283 |
335 |
MWF/FubRkb |
urine albumin excretion rate |
control condition |
Schulz A, et al., J Am Soc Nephrol. 2007 Jan;18(1):113-21 |
urine albumin amount |
not specified |
56 days
| 18 |
18.1 |
mg/d |
2.0 |
8.49 |
|
enzyme linked immunosorbent assay |
|
0.0 |
|
0 |
|
|
|
|
65273 |
117 |
SS-Adra2aem1Mcwi-/- |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine albumin amount |
male |
70 days-77 days |
8 |
28.05 |
mg/d |
5.32 |
15.04 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
- |
43585 |
421 |
SS-Sh2b3em1Mcwi-/+ |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine albumin amount |
male |
70 days-77 days |
3 |
16.02 |
mg/d |
3.39 |
5.88 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
- |
43590 |
421 |
SS-Ulk3em4Mcwi-/+ |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine albumin amount |
male |
70 days-77 days |
4 |
30.07 |
mg/d |
12.74 |
25.47 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
- |
43594 |
421 |
SS-Agtrapem4Mcwi-/- |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine albumin amount |
male |
70 days-77 days |
7 |
70.31 |
mg/d |
29.32 |
77.57 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
- |
43596 |
421 |
SS-Hexim2em4Mcwi-/- |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine albumin amount |
male |
70 days-77 days |
10 |
37.47 |
mg/d |
6.37 |
20.14 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
- |
43598 |
421 |
SS-Agtr1aem1Mcwi+/+ |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine albumin amount |
male |
70 days-77 days |
6 |
50.27 |
mg/d |
20.21 |
49.51 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
- |
44259 |
441 |
SS-Wdr72em1Mcwi-/- |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine albumin amount |
male |
70 days-77 days |
1 |
112.98 |
mg/d |
|
|
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
- |
44278 |
441 |
SS-Plod1em1Mcwi-/- |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine albumin amount |
male |
70 days-77 days |
12 |
59.54 |
mg/d |
6.96 |
24.12 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
- |
44286 |
441 |
SS-Plekha7em1Mcwi-/- |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine albumin amount |
male |
70 days-77 days |
9 |
31.02 |
mg/d |
3.97 |
11.9 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
- |
44288 |
441 |
SS-Plcd3em7Mcwi-/- |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine albumin amount |
male |
70 days-77 days |
10 |
59.6 |
mg/d |
8.7 |
27.51 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
- |
44296 |
441 |
SS-Cyp1a1em1Mcwi-/- |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine albumin amount |
male |
70 days-77 days |
7 |
33.13 |
mg/d |
7.01 |
18.54 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
- |
44301 |
441 |
SS/JrHsdMcwi |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine albumin amount |
male |
70 days-77 days |
7 |
75.58 |
mg/d |
16.27 |
43.05 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
- |
44302 |
441 |
SS-Nppbem2Mcwi-/- |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 14 days) |
PhysGen Knockout data |
urine albumin amount |
male |
70 days-77 days |
16 |
58.99 |
mg/d |
9.31 |
37.24 |
Download Values
|
automated urine analysis |
|
|
|
0 |
|
|
|
- |
44309 |
441 |
LL/Mav |
urine albumin excretion rate |
vehicle control condition |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
urine albumin amount |
male |
112 days
| 9 |
4.4 |
mg/d |
0.3 |
0.9 |
|
urine albumin analysis |
|
0.0 |
|
0 |
|
|
|
|
102738 |
2721 |
LH/Mav |
urine albumin excretion rate |
streptozotocin (75 mg/kg) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
urine albumin amount |
male |
112 days
| 14 |
35.6 |
mg/d |
1.8 |
6.73 |
|
urine albumin analysis |
|
0.0 |
|
0 |
|
|
|
|
102741 |
2721 |
SS.BN-(D13Got42-D13Got45)/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days) |
Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. |
urine albumin amount |
male |
60 days-67 days |
13 |
240.0 |
mg/d |
29.0 |
104.56 |
|
urine microalbumin analysis |
|
0.0 |
|
0 |
|
|
strain 26-B |
|
98627 |
2098 |
SS.BN-(D13Got42-D13Rat130)/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days) |
Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. |
urine albumin amount |
male |
60 days-67 days |
14 |
239.0 |
mg/d |
29.0 |
108.51 |
|
urine microalbumin analysis |
|
0.0 |
|
0 |
|
|
strain 26-C |
|
98628 |
2098 |
SS.BN-(D13Got45-D13Hmgc664)/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days) |
Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. |
urine albumin amount |
male |
60 days-67 days |
14 |
167.0 |
mg/d |
28.0 |
104.77 |
|
urine microalbumin analysis |
|
0.0 |
|
0 |
|
|
strain 26-M |
|
98638 |
2098 |
SS.BN-(D13Hmgc1048-D13Hmgc664)/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (0.4 %) (between 20 and 29 days) |
Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. |
urine albumin amount |
male |
41 days-50 days |
15 |
1.7 |
mg/d |
0.4 |
1.55 |
|
urine microalbumin analysis |
|
86400.0 |
|
0 |
|
|
strain 26-N |
|
98529 |
2079 |
SS.BN-(D13Hmgc1048-D13Hmgc1050)/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (0.4 %) (between 20 and 29 days) |
Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. |
urine albumin amount |
male |
41 days-50 days |
11 |
2.2 |
mg/d |
0.3 |
0.99 |
|
urine microalbumin analysis |
|
86400.0 |
|
0 |
|
|
strain 26-P |
|
98531 |
2079 |
SS.BN-(D13Hmgc1041-D13Hmgc664)/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days) |
Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. |
urine albumin amount |
male |
59 days-68 days |
13 |
252.0 |
mg/d |
25.0 |
90.14 |
|
urine microalbumin analysis |
|
86400.0 |
|
0 |
|
|
strain 26-Q |
|
98539 |
2079 |
SS.BN-(D13Hmgc1041-D13Hmgc664)/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (0.4 %) (between 20 and 29 days) |
Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. |
urine albumin amount |
male |
41 days-50 days |
13 |
2.9 |
mg/d |
0.5 |
1.8 |
|
urine microalbumin analysis |
|
86400.0 |
|
0 |
|
|
strain 26-Q |
|
98532 |
2079 |
SS.BN-(D13Hmgc64-RN34_13048990782)/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (0.4 %) (for 70 days) then controlled sodium content diet (8 %) (for 21 days) |
Hoffman MJ, et al., Hypertension. 2013 Sep;62(3):557-63. doi: 10.1161/HYPERTENSIONAHA.113.01708. Epub 2013 Jul 1. |
urine albumin amount |
female |
91 days
| 11 |
45.0 |
mg/d |
12.0 |
39.8 |
|
urine microalbumin analysis |
|
1.0 |
|
0 |
|
|
|
|
98712 |
2141 |
SS/JrHsdMcwi |
urine albumin excretion rate |
controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days) |
Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. |
urine albumin amount |
male |
59 days-68 days |
14 |
278.0 |
mg/d |
18.0 |
67.35 |
|
urine microalbumin analysis |
|
86400.0 |
|
0 |
|
|
|
|
98535 |
2079 |
ACI.FHH-(rs105487995-rs106411696)/Mcwi |
urine albumin excretion rate |
unilateral nephrectomy then NG-nitroarginine methyl ester (150 mg/l) (for 56 days) |
Lazar J, et al., Physiol Genomics. 2013 Aug 15;45(16):720-8. doi: 10.1152/physiolgenomics.00089.2013. Epub 2013 Jun 18. |
urine albumin amount |
male |
91 days
| 8 |
33.72 |
mg/d |
6.92 |
19.57 |
|
urine albumin analysis |
|
0.0 |
unx |
56 |
days |
|
rf-1-2 |
|
100061 |
2400 |
ACI.FHH-(rs198076037-rs105278863)/Mcwi |
urine albumin excretion rate |
unilateral nephrectomy then NG-nitroarginine methyl ester (150 mg/l) (for 56 days) |
Lazar J, et al., Physiol Genomics. 2013 Aug 15;45(16):720-8. doi: 10.1152/physiolgenomics.00089.2013. Epub 2013 Jun 18. |
urine albumin amount |
male |
91 days
| 5 |
69.44 |
mg/d |
7.49 |
16.75 |
|
urine albumin analysis |
|
0.0 |
unx |
56 |
days |
|
rf-1-7 |
|
100066 |
2400 |
FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi |
urine albumin excretion rate |
control condition (for 84 days) |
Rangel-Filho A, et al., J Am Soc Nephrol. 2013 Feb;24(2):283-92. doi: 10.1681/ASN.2012090927. Epub 2013 Jan 4. |
urine albumin amount |
male |
84 days
| 5 |
30.0 |
mg/d |
4.0 |
8.94 |
|
urine albumin analysis |
|
0.0 |
|
0 |
|
|
|
|
104249 |
2946 |
FHH |
urine albumin excretion rate |
control condition (for 84 days) |
Rangel-Filho A, et al., J Am Soc Nephrol. 2013 Feb;24(2):283-92. doi: 10.1681/ASN.2012090927. Epub 2013 Jan 4. |
urine albumin amount |
male |
84 days
| 8 |
68.0 |
mg/d |
18.0 |
50.91 |
|
urine albumin analysis |
|
0.0 |
|
0 |
|
|
|
|
104250 |
2946 |
SS-Sh2b3em1Mcwi-/- |
urine albumin excretion rate |
controlled sodium chloride content diet (0.4 %) (for 42 days) then controlled sodium chloride content diet (4 %) (for 10 days) |
Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. |
urine albumin amount |
not specified |
73 days
| 6 |
9.4 |
mg/d |
2.4 |
5.88 |
|
urine albumin analysis |
|
0.0 |
|
0 |
|
|
n=6-8 |
|
106527 |
3031 |
SS/JrHsdMcwi |
urine albumin excretion rate |
controlled sodium chloride content diet (0.4 %) (for 42 days) then controlled sodium chloride content diet (4 %) (for 21 days) |
Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. |
urine albumin amount |
not specified |
84 days
| 6 |
104.9 |
mg/d |
8.9 |
21.8 |
|
urine albumin analysis |
|
0.0 |
|
0 |
|
|
n=6-8 |
|
106528 |
3031 |
SHRSP/A3NCrl |
urine albumin excretion rate |
controlled fat content diet (24.5 %) (for 56 days) and controlled sodium chloride content drinking water (1 %) (for 56 days) |
Lenhard SC, etal., J Pharmacol Exp Ther. 2003 Dec;307(3):939-46. doi: 10.1124/jpet.103.057398. Epub 2003 Oct 15. |
urine albumin amount |
male |
126 days-140 days |
6 |
22.9 |
mg/d |
5.1 |
12.49 |
|
urine albumin analysis |
|
0.0 |
|
0 |
|
immunoturbidimetric assay |
baseline vehicle group |
|
107376 |
3083 |
GK/Jpe |
urine albumin excretion rate |
controlled cholesterol content diet (1.25 %) (for 90 days) and controlled cocoa butter content diet (7.5 %) (for 90 days) and lipoic acid (50 mg/kg) (for 90 days) |
Sena CM, etal., Br J Pharmacol. 2008 Mar;153(5):894-906. doi: 10.1038/sj.bjp.0707474. Epub 2007 Oct 1. |
urine albumin amount |
male |
540 days
| 10 |
17.8 |
mg/d |
2.9 |
9.17 |
|
urine albumin analysis |
|
0.0 |
|
0 |
|
|
|
|
108023 |
3108 |
SHR-Chr 6MWF/Rkb |
urine albumin excretion rate |
sham surgical control condition |
Schulz A, etal., Physiol Genomics. 2010 Jun. |
urine albumin amount |
male |
168 days
| 10 |
0.5 |
mg/d |
0.2 |
0.63 |
|
enzyme linked immunosorbent assay |
|
0.0 |
|
0 |
|
|
|
|
108127 |
3116 |
MWF/FubRkb |
urine albumin excretion rate |
control condition |
Ijpelaar DH, etal., Am J Physiol Renal Physiol. 2008 Apr;294(4):F758-67. Epub 2008 Jan 16. |
urine albumin amount |
male |
30 days
| 5 |
0.14 |
mg/d |
0.05 |
0.11 |
|
enzyme linked immunosorbent assay |
|
0.0 |
|
0 |
|
|
|
|
109715 |
3152 |
MWF/FubRkb |
urine albumin excretion rate |
control condition |
Ijpelaar DH, etal., Am J Physiol Renal Physiol. 2008 Apr;294(4):F758-67. Epub 2008 Jan 16. |
urine albumin amount |
female |
30 days
| 5 |
0.11 |
mg/d |
0.02 |
0.04 |
|
enzyme linked immunosorbent assay |
|
0.0 |
|
0 |
|
|
|
|
109716 |
3152 |
MWF/FubRkb |
urine albumin excretion rate |
control condition |
Ijpelaar DH, etal., Am J Physiol Renal Physiol. 2008 Apr;294(4):F758-67. Epub 2008 Jan 16. |
urine albumin amount |
female |
44 days
| 5 |
11.7 |
mg/d |
4.47 |
10.0 |
|
enzyme linked immunosorbent assay |
|
0.0 |
|
0 |
|
|
|
|
109718 |
3152 |
MWF/FubRkb |
urine albumin excretion rate |
sham surgical control condition |
Schulz A, etal., Physiol Genomics. 2010 Jun. |
urine albumin amount |
male |
168 days
| 10 |
108.7 |
mg/d |
12.3 |
38.9 |
|
enzyme linked immunosorbent assay |
|
0.0 |
|
0 |
|
|
|
|
108124 |
3116 |
BN/NHsdMcwi |
urine albumin excretion rate |
control condition |
Nobrega MA, et al., Diabetes 2004 Mar;53(3):735-42. |
urine albumin amount |
male |
180 days
| 0 |
0.7 |
mg/d |
0.1 |
|
|
albumin blue 580-based urine albumin analysis with spectrophotometric readout |
|
86400.0 |
|
0 |
|
albumin blue 580-based urine albumin analysis with spectrophotometric readout (MMO:0000756) |
n=6-27 |
|
110566 |
3177 |
SHRSP/A3NCrl |
urine albumin excretion rate |
controlled sodium chloride content drinking water (1 %) (for 56 days) and controlled fat content diet (24.5 %) (for 56 days) |
Costell MH, etal., Front Pharmacol. 2012 Jul 5;3:128. doi: 10.3389/fphar.2012.00128. eCollection 2012. |
urine albumin amount |
male |
84 days-91 days |
9 |
1.3 |
mg/d |
0.03 |
0.09 |
|
urine microalbumin analysis |
|
86400.0 |
|
0 |
|
baseline |
baseline high salt high fat diet group |
|
107058 |
3073 |
MWF/FubRkb |
urine albumin excretion rate |
sham surgical control condition (for 84 days) |
Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. |
urine albumin amount |
not specified |
84 days
| 15 |
58.1 |
mg/d |
5.8 |
22.46 |
|
enzyme linked immunosorbent assay |
|
0.0 |
|
0 |
|
|
|
|
109659 |
3149 |
MWF/FubRkb |
urine albumin excretion rate |
left nephrectomy (for 84 days) |
Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. |
urine albumin amount |
not specified |
84 days
| 15 |
124.1 |
mg/d |
10.9 |
42.22 |
|
enzyme linked immunosorbent assay |
|
0.0 |
|
0 |
|
|
|
|
109661 |
3149 |
MWF-Chr 8SHR/Rkb |
urine albumin excretion rate |
control condition |
Schulz A, etal., Physiol Genomics. 2008 Sep 17;35(1):30-5. Epub 2008 Jul 22. |
urine albumin amount |
female |
56 days
| 20 |
0.4 |
mg/d |
0.1 |
0.45 |
|
enzyme linked immunosorbent assay |
|
0.0 |
|
0 |
|
|
|
|
108968 |
3133 |
SS.BN-(D13Rat7-D13Rat60)/Mcwi |
urine albumin excretion rate |
controlled sodium content diet (8 %) (for 18 days) |
Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. |
urine albumin amount |
female |
84 days-88 days |
12 |
22.4 |
mg/d |
4.1 |
14.2 |
|
urine analysis |
|
86400 |
|
0 |
|
|
|
|
65204 |
15 |
|