SS-Sh2b3em1Mcwi-/- |
blood mononuclear cell count |
controlled sodium chloride content diet (0.4 %) (for 21 days) |
Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. |
leukocyte quantity |
not specified |
84 days
| 4 |
|
14.7 |
x 10E6 cells/ml |
0.6 |
1.2 |
flow cytometry method |
0.0 |
0 |
n=4-7 |
106511 |
3031 |
SS-Sh2b3em1Mcwi-/- |
spleen regulatory T cell count to total T cell count ratio |
controlled sodium chloride content diet (0.4 %) (for 42 days) |
Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. |
T cell quantity |
not specified |
63 days
| 4 |
|
5.2 |
% |
0.3 |
0.6 |
flow cytometry method |
0.0 |
0 |
n=4-7 -tregs blood % |
106517 |
3031 |
SS-Sh2b3em1Mcwi-/- |
urine albumin excretion rate |
controlled sodium chloride content diet (0.4 %) (for 42 days) |
Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. |
urine albumin amount |
not specified |
63 days
| 6 |
|
3.6 |
mg/d |
0.3 |
0.73 |
urine albumin analysis |
0.0 |
0 |
n=6-8 |
106525 |
3031 |
SS-Sh2b3em1Mcwi-/- |
urine albumin excretion rate |
controlled sodium chloride content diet (0.4 %) (for 42 days) then controlled sodium chloride content diet (4 %) (for 21 days) |
Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. |
urine albumin amount |
not specified |
84 days
| 6 |
|
30.3 |
mg/d |
7.0 |
17.15 |
urine albumin analysis |
0.0 |
0 |
n=6-8 |
106529 |
3031 |
SS-Sh2b3em1Mcwi-/- |
spleen weight |
controlled sodium chloride content diet (0.4 %) (for 42 days) |
Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. |
spleen mass |
not specified |
63 days
| 4 |
|
2.4 |
g |
0.2 |
0.4 |
post excision weight measurement |
0.0 |
0 |
n=4-7 |
106509 |
3031 |
SS-Sh2b3em1Mcwi-/- |
blood B lymphocyte count |
controlled sodium chloride content diet (0.4 %) (for 42 days) |
Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. |
B cell quantity |
not specified |
63 days
| 4 |
|
4.0 |
x 10E6 cells/ml |
0.3 |
0.6 |
flow cytometry method |
0.0 |
0 |
n=4-7 |
106515 |
3031 |
SS-Sh2b3em1Mcwi-/- |
mean arterial blood pressure |
controlled sodium chloride content diet (0.4 %) (for 70 days) then controlled sodium chloride content diet (4 %) (for 21 days) |
Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. |
arterial blood pressure trait |
not specified |
91 days
| 6 |
15sec/min for 3 hrs/day |
135.7 |
mmHg |
1.1 |
2.69 |
vascular fluid filled catheter |
0.0 |
0 |
n=6-8 |
106523 |
3031 |
SS-Sh2b3em1Mcwi-/- |
urine albumin excretion rate |
controlled sodium chloride content diet (0.4 %) (for 42 days) then controlled sodium chloride content diet (4 %) (for 10 days) |
Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. |
urine albumin amount |
not specified |
73 days
| 6 |
|
9.4 |
mg/d |
2.4 |
5.88 |
urine albumin analysis |
0.0 |
0 |
n=6-8 |
106527 |
3031 |
SS-Sh2b3em1Mcwi-/- |
blood T lymphocyte count |
controlled sodium chloride content diet (0.4 %) (for 42 days) |
Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. |
T cell quantity |
not specified |
63 days
| 4 |
|
7.0 |
x 10E6 cells/ml |
0.4 |
0.8 |
flow cytometry method |
0.0 |
0 |
n=4-7 |
106513 |
3031 |
SS-Sh2b3em1Mcwi-/- |
blood regulatory T cell count to total T cell count ratio |
controlled sodium chloride content diet (0.4 %) (for 42 days) |
Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. |
T cell quantity |
not specified |
63 days
| 4 |
|
4.9 |
% |
0.1 |
0.2 |
flow cytometry method |
0.0 |
0 |
n=4-7 -tregs spleen % |
106519 |
3031 |
SS-Sh2b3em1Mcwi-/- |
kidney total CD45 positive leukocyte count |
controlled sodium chloride content diet (0.4 %) (for 21 days) then controlled sodium chloride content diet (4 %) (for 21 days) |
Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. |
leukocyte quantity |
not specified |
84 days
| 5 |
|
1.84 |
x 10E6 cells/ml |
0.3 |
0.67 |
flow cytometry method |
0.0 |
0 |
n=5-6 |
106534 |
3031 |
SS-Sh2b3em1Mcwi-/- |
mean arterial blood pressure |
controlled sodium chloride content diet (0.4 %) (for 70 days) |
Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. |
arterial blood pressure trait |
not specified |
70 days
| 6 |
15sec/min for 3 hrs/day for 7days |
127.7 |
mmHg |
2.0 |
4.9 |
vascular fluid filled catheter |
0.0 |
0 |
n=6-8 |
106521 |
3031 |