SD-Abcb1aem1Sage-/- |
brain uptake index of quinidine |
tritiated quinidine (10 uCi) (for 0 hours) and quinidine (10 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
brain molecular composition trait |
male |
42 days-56 days |
3 |
21.6 |
% |
0.6 |
1.04 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
sec post excision |
quinidine uptake index |
|
106160 |
3028 |
SD-Abcb1aem1Sage-/- |
brain uptake index of quinidine |
tritiated quinidine (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
brain molecular composition trait |
male |
42 days-56 days |
3 |
12.4 |
% |
1.7 |
2.94 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
sec post excision |
quinidine uptake index |
|
106161 |
3028 |
SD-Abcb1aem1Sage-/- |
aqueous humor uptake index of quinidine |
tritiated quinidine (10 uCi) (for 0 hours) and quinidine (10 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
REQUEST NEW TERM (00:0000000) |
male |
35 days-49 days |
3 |
12.5 |
% |
0.7 |
1.21 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
sec post excision |
quinidine uptake index |
aqueous humor molecular composition trait |
106142 |
3028 |
SD-Abcb1aem1Sage-/- |
aqueous humor uptake index of quinidine |
tritiated quinidine (10 uCi) (for 0 hours) and vehicle control condition (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
REQUEST NEW TERM (00:0000000) |
male |
42 days-56 days |
3 |
12.0 |
% |
0.6 |
1.04 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
sec post excision |
quinidine uptake index |
aqueous humor molecular composition trait |
106141 |
3028 |
SD-Abcb1aem1Sage-/- |
retinal uptake index of quinidine |
tritiated quinidine (10 uCi) (for 0 hours) and vehicle control condition (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
retina molecular composition trait |
male |
42 days-56 days |
3 |
227.0 |
% |
25.0 |
43.3 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
sec post excision |
quinidine uptake index |
|
106123 |
3028 |
SD-Abcb1aem1Sage-/- |
retinal uptake index of quinidine |
tritiated quinidine (10 uCi) (for 0 hours) and quinidine (10 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
retina molecular composition trait |
male |
42 days-56 days |
3 |
182.0 |
% |
24.0 |
41.57 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
sec post excision |
quinidine uptake index |
|
106124 |
3028 |
SD-Abcb1aem1Sage-/- |
aqueous humor uptake index of quinidine |
tritiated quinidine (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
REQUEST NEW TERM (00:0000000) |
male |
35 days-49 days |
3 |
8.83 |
% |
0.4 |
0.69 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
sec post excision |
quinidine uptake index |
aqueous humor molecular composition trait |
106143 |
3028 |
SD-Abcb1aem1Sage-/- |
retinal uptake index of quinidine |
tritiated quinidine (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
retina molecular composition trait |
male |
42 days-56 days |
3 |
142.0 |
% |
5.0 |
8.66 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
sec post excision |
quinidine uptake index |
|
106125 |
3028 |
SD-Abcb1aem1Sage-/- |
brain uptake index of quinidine |
tritiated quinidine (10 uCi) (for 0 hours) and vehicle control condition |
Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. |
brain molecular composition trait |
male |
42 days-56 days |
3 |
26.1 |
% |
2.4 |
4.16 |
liquid scintillation counting |
0.0 |
carotid injection |
15 |
sec post excision |
quinidine uptake index |
|
106159 |
3028 |