Phenominer Database Results (40 results)

 

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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Site Method Duration Post Insult Time Value Record ID Study ID
LH/Mav heart left ventricle weight to body weight ratio perindopril (1.5 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. heart left ventricle mass male 119 days 8 2.37 mg/g 0.07 0.2 post excision weight measurement 0.0 0 103411 2824
LH/Mav aorta weight to body weight ratio perindopril (0.4 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. aorta mass male 119 days 8 12.5 mg/100g 0.6 1.7 post excision weight measurement 0.0 0 103415 2824
LH/Mav body weight perindopril (0.4 mg/kg/d) (for 98 days) Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. body mass male 161 days 8 459.0 g 10.0 28.28 body weighing method 0.0 0 102804 2723
LH/Mav body weight perindopril (0.04 mg/kg/d) (for 98 days) Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. body mass male 161 days 6 457.0 g 11.0 26.94 body weighing method 0.0 0 102807 2723
LH/Mav plasma total cholesterol level streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. blood cholesterol amount male 112 days 11 73.36 mg/dl 4.63 15.37 blood cholesterol analysis 0.0 0 102666 2703
LH/Mav body weight perindopril (0.1 mg/kg/d) (for 98 days) Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. body mass male 112 days 8 404.0 g 6.0 16.97 body weighing method 0.0 0 102789 2723
LH/Mav renal vascular resistance to kidney weight ratio perindopril (1.5 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. kidney blood vessel physiology trait male 84 days 7 SBP/RBF 23.0 ml/min/g/mmHg 2.0 5.29 ultrasonic flowmeter 0.0 0 102858 2761
LH/Mav renal blood flow rate to kidney weight ratio perindopril (1.5 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. renal blood flow trait male 84 days 7 5.3 ml/min/g 0.5 1.32 ultrasonic flowmeter 0.0 0 102854 2761
LH/Mav heart left ventricle weight to body weight ratio perindopril (0.4 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. heart left ventricle mass male 119 days 8 2.41 mg/g 0.08 0.23 post excision weight measurement 0.0 0 103410 2824
LH/Mav plasma creatinine level streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. blood creatinine amount male 112 days 9 0.54 mg/dl 0.01 0.03 plasma creatinine analysis 0.0 0 102677 2703
SHR/N-cp serum glucose level standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 112 and 126 days) then perindopril (0.25-0.5 mg/kg/d) (between 56 and 70 days) Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. blood glucose amount male 140 days-168 days 8 179.69 mg/dl 21.78 61.6 serum glucose analysis 0.0 0 101506 2601
SHR/N-cp serum glucose level standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then perindopril (0.25-0.5 mg/kg/d) (between 84 and 98 days) Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. blood glucose amount male 168 days-196 days 8 139.76 mg/dl 18.15 51.34 serum glucose analysis 0.0 0 101509 2601
SHR/N-cp both kidneys wet weight to body weight ratio standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then perindopril (0.25-0.5 mg/kg/d) (between 84 and 98 days) Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. kidney mass male 168 days-196 days 8 1.67 g/kg 0.1 0.28 post excision weight measurement 0.0 0 101524 2601
LH/Mav both kidneys wet weight to body weight ratio streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. kidney mass male 112 days 9 7.02 g/kg 0.18 0.54 post excision weight measurement 0.0 0 102695 2703
LH/Mav both kidneys wet weight to body weight ratio streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. kidney mass male 112 days 11 6.44 g/kg 0.14 0.46 post excision weight measurement 0.0 0 102696 2703
LH/Mav body weight perindopril (0.04 mg/kg/d) (for 98 days) Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. body mass male 112 days 8 394.0 g 4.0 11.31 body weighing method 0.0 0 102788 2723
LH/Mav systolic blood pressure perindopril (1.5 mg/kg/d) (for 42 days) Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. arterial blood pressure trait male 63 days 7 undefined 113.0 mmHg 3.0 7.94 tail cuff plethysmography 0.0 0 102850 2761
LH/Mav both kidneys wet weight to body weight ratio perindopril (1.5 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. kidney mass male 119 days 8 5.87 g/kg 0.1 0.28 post excision weight measurement 0.0 0 103421 2824
LH/Mav body weight perindopril (0.1 mg/kg/d) (for 98 days) Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. body mass male 161 days 8 452.0 g 5.0 14.14 body weighing method 0.0 0 102803 2723
LH/Mav body weight perindopril (0.04 mg/kg/d) (for 98 days) Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. body mass male 161 days 8 442.0 g 6.0 16.97 body weighing method 0.0 0 102802 2723
LH/Mav body weight perindopril (0.01 mg/kg/d) (for 98 days) Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. body mass male 161 days 6 460.0 g 14.0 34.29 body weighing method 0.0 0 102806 2723
LH/Mav plasma triglyceride level streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. blood triglyceride amount male 112 days 10 2.42 mmol/l 0.3 0.95 plasma triglyceride analysis 0.0 0 102671 2703
SHR/N-cp serum glucose level standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 84 and 98 days) then perindopril (0.25-0.5 mg/kg/d) (between 28 and 42 days) Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. blood glucose amount male 112 days-140 days 8 192.39 mg/dl 29.04 82.14 serum glucose analysis 0.0 0 101503 2601
SHR/N-cp kidney sclerotic glomeruli count to total glomeruli count ratio standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then perindopril (0.25-0.5 mg/kg/d) (between 84 and 98 days) Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. kidney glomerulus integrity trait male 168 days-196 days 8 9.0 % 4.0 11.31 ex vivo light microscopy with histochemistry 0.0 0 101527 2601
Crl:SD systolic blood pressure controlled protein content diet (20 %) then perindopril (1 mg/kg/d) (for 120 days) Zoja C, etal., Am J Med. 1992 Apr 27;92(4B):60S-63S. doi: 10.1016/0002-9343(92)90149-6. arterial blood pressure trait male 540 days-660 days 8 130.0 mmHg 7.0 19.8 tail cuff plethysmography tail 0.0 0 108594 3126
LH/Mav body weight perindopril (0.4 mg/kg/d) (for 98 days) Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. body mass male 112 days 8 405.0 g 7.0 19.8 body weighing method 0.0 0 102790 2723
LH/Mav body weight perindopril (0.01 mg/kg/d) (for 98 days) Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. body mass male 112 days 6 391.0 g 8.0 19.6 body weighing method 0.0 0 102792 2723
LH/Mav aorta weight to body weight ratio perindopril (1.5 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. aorta mass male 119 days 8 13.6 mg/100g 0.5 1.41 post excision weight measurement 0.0 0 103416 2824
LH/Mav plasma triglyceride level streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. blood triglyceride amount male 112 days 11 1.5 mmol/l 0.12 0.4 plasma triglyceride analysis 0.0 0 102672 2703
LH/Mav plasma creatinine level streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. blood creatinine amount male 112 days 11 0.54 mg/dl 0.01 0.03 plasma creatinine analysis 0.0 0 102678 2703
LH/Mav heart left ventricle weight to body weight ratio streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. heart left ventricle mass male 112 days 9 23.8 mg/g 0.8 2.4 post excision weight measurement 0.0 0 102683 2703
LH/Mav aorta weight to body weight ratio streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. aorta mass male 112 days 9 12.3 mg/100g 0.4 1.2 post excision weight measurement 0.0 0 102689 2703
LH/Mav body weight perindopril (0.04 mg/kg/d) (for 98 days) Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. body mass male 112 days 6 372.0 g 9.0 22.05 body weighing method 0.0 0 102793 2723
SHR/N-cp serum glucose level standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 42 and 56 days) then perindopril (0.25-0.5 mg/kg/d) Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. blood glucose amount male 70 days-98 days 8 154.28 mg/dl 19.97 56.47 serum glucose analysis 0.0 0 101500 2601
SHR/N-cp plasma renin activity level standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then perindopril (0.25-0.5 mg/kg/d) (between 84 and 98 days) Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. renin activity male 168 days-196 days 8 52.0 ng/ml/h 8.0 22.63 radioimmunoassay 0.0 0 101533 2601
Crl:SD urine total protein excretion rate controlled protein content diet (20 %) then perindopril (1 mg/kg/d) (for 120 days) Zoja C, etal., Am J Med. 1992 Apr 27;92(4B):60S-63S. doi: 10.1016/0002-9343(92)90149-6. total urine protein amount male 540 days-660 days 8 32.0 mg/d 9.0 25.46 Bradford protein assay 0.0 0 108597 3126
LH/Mav both kidneys wet weight to body weight ratio perindopril (0.4 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. kidney mass male 119 days 8 6.22 g/kg 0.21 0.59 post excision weight measurement 0.0 0 103420 2824
LH/Mav plasma total cholesterol level streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. blood cholesterol amount male 112 days 10 83.78 mg/dl 6.56 20.76 blood cholesterol analysis 0.0 0 102665 2703
LH/Mav heart left ventricle weight to body weight ratio streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. heart left ventricle mass male 112 days 11 19.9 mg/g 0.5 1.66 post excision weight measurement 0.0 0 102684 2703
LH/Mav aorta weight to body weight ratio streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. aorta mass male 112 days 11 10.1 mg/100g 0.2 0.66 post excision weight measurement 0.0 0 102690 2703