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Strain
Phenotype
Conditions
Study
Experiment Name
Sex
Age
# of Animals
Value
Units
SEM
SD
Method
Method Duration
Post Insult Type
Post Insult Time Value
Post Insult Time Unit
Method Notes
Clinical Measurement Notes
Record ID
Study ID
BN/SsN
calculated serum anti-rat type 2 collagen autoantibody titer
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %)
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89
blood autoantibody amount
both
66 days-126 days
13
2.0
null
0.55
2.0
enzyme linked immunosorbent assay
0.0
immunized
10
days
variable
titer
69965
850
BN/SsN
calculated serum anti-rat type 2 collagen autoantibody titer
Freund's incomplete adjuvant (50 %) and type II collagen (2 mg/kg)
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50
blood autoantibody amount
female
66 days-126 days
7
1.9
null
0.68
1.8
enzyme linked immunosorbent assay
0.0
0
titer
69928
1241
BN/SsN
calculated serum anti-porcine type 2 collagen antibody titer
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %)
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89
blood immunoglobulin amount
both
66 days-126 days
13
3.0
null
0.55
2.0
enzyme linked immunosorbent assay
0.0
immunized
10
days
variable
titer
69964
850
BN/SsN
percentage of study population developing chronic experimental arthritis during a period of time
Freund's incomplete adjuvant (50 %) (between 1 and 7 days) and type II collagen (2 mg/kg) (between 1 and 7 days) then Freund's incomplete adjuvant (50 %) (between 1 and 35 days) and type II collagen (100 ug) (between 1 and 35 days)
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50
joint integrity trait
female
66 days-126 days
7
0.0
%
in vivo visual assessment
0.0
0
69924
1241
BN/SsN
percentage of study population developing experimental arthritis during a period of time
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %)
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89
joint integrity trait
both
66 days-126 days
13
0.0
%
in vivo visual assessment
0.0
immunized
10
days
variable
69961
850
BN/SsN
percentage of study population developing chronic experimental arthritis during a period of time
Freund's incomplete adjuvant (50 %) (between 1 and 7 days) and type II collagen (2 mg/kg) (between 1 and 7 days) then Freund's incomplete adjuvant (50 %) (between 1 and 35 days) and type II collagen (100 ug) (between 1 and 35 days)
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50
joint integrity trait
male
66 days-126 days
13
0.0
%
in vivo visual assessment
0.0
0
69923
1241
BN/SsN
body weight loss
type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %)
Griffiths MM, et al., Arthritis Rheum 2000 Jun;43(6):1278-89
body mass
both
66 days-126 days
13
0.0
%
0.0
0.0
body weighing method
0.0
immunized
10
days
variable
(weight loss)
69958
850
BN/SsN
calculated serum anti-rat type 2 collagen autoantibody titer
Freund's incomplete adjuvant (50 %) and type II collagen (2 mg/kg)
Furuya T, et al., Hum Mol Genet 2000 Sep 22;9(15):2241-50
blood autoantibody amount
male
66 days-126 days
13
1.3
null
0.28
1.0
enzyme linked immunosorbent assay
0.0
0
titer
69927
1241