SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb |
percentage of study population developing cerebrovascular lesions during a period of time |
controlled sodium content diet (3.7 mg/g) (between 28 and 49 days) and controlled sodium content drinking water (1 %) (between 28 and 49 days) and controlled potassium content diet (6.3 mg/g) (between 28 and 49 days) |
Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. |
cerebrovascular system integrity trait |
not specified |
70 days-91 days |
20 |
61.0 |
% |
|
|
ex vivo light microscopy |
0.0 |
0 |
69121 |
1126 |
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb |
urine total protein excretion rate |
controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days) |
Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. |
total urine protein amount |
not specified |
84 days
| 20 |
232.0 |
mg/d |
20.35 |
91.0 |
Bradford protein assay |
0.0 |
0 |
70259 |
1126 |
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb |
systolic blood pressure |
controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) |
Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. |
arterial blood pressure trait |
not specified |
70 days
| 33 |
186.0 |
mmHg |
1.2 |
6.9 |
tail cuff plethysmography |
0.0 |
0 |
69188 |
1126 |
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb |
systolic blood pressure |
controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days) |
Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. |
arterial blood pressure trait |
not specified |
56 days
| 33 |
164.0 |
mmHg |
2.61 |
15.0 |
tail cuff plethysmography |
0.0 |
0 |
69187 |
1126 |
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb |
urine total protein excretion rate |
controlled sodium content diet (3.7 mg/g) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) |
Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. |
total urine protein amount |
not specified |
98 days
| 3 |
351.0 |
mg/d |
28.87 |
50.0 |
Bradford protein assay |
0.0 |
0 |
70260 |
1126 |
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb |
urine total protein excretion rate |
controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) |
Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. |
total urine protein amount |
not specified |
70 days
| 33 |
30.0 |
mg/d |
0.92 |
5.3 |
Bradford protein assay |
0.0 |
0 |
70258 |
1126 |
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb |
percentage of study population developing cerebrovascular lesions during a period of time |
controlled sodium content diet (3.7 mg/g) (between 28 and 67 days) and controlled sodium content drinking water (1 %) (between 28 and 67 days) and controlled potassium content diet (6.3 mg/g) (between 28 and 67 days) |
Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. |
cerebrovascular system integrity trait |
not specified |
70 days-109 days |
33 |
100.0 |
% |
|
|
ex vivo light microscopy |
0.0 |
0 |
84575 |
1126 |
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb |
systolic blood pressure |
controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days) |
Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. |
arterial blood pressure trait |
not specified |
84 days
| 20 |
192.0 |
mmHg |
1.57 |
7.0 |
tail cuff plethysmography |
0.0 |
0 |
69189 |
1126 |
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb |
systolic blood pressure |
controlled sodium content diet (3.7 mg/g) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) |
Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. |
arterial blood pressure trait |
not specified |
98 days
| 3 |
195.0 |
mmHg |
2.89 |
5.0 |
tail cuff plethysmography |
0.0 |
0 |
69190 |
1126 |
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb |
urine total protein excretion rate |
controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days) |
Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. |
total urine protein amount |
not specified |
56 days
| 33 |
38.0 |
mg/d |
1.91 |
11.0 |
Bradford protein assay |
0.0 |
0 |
70257 |
1126 |