9 | concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) | FHH-Chr 8BN/Mcwi | female | 1.6192 | E-7mole | phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) | 55905 | phenylephrine (1 umol/l) (for 0.2 hours) | | acetylcholine (0-30 umol/l) | drug dose time series (for 1 hours) | | |

9 | concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) | FHH-Chr 8BN/Mcwi | male | 1.354 | E-7mole | phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) | 55917 | phenylephrine (1 umol/l) (for 0.2 hours) | | acetylcholine (0-30 umol/l) | drug dose time series (for 1 hours) | | |

10 | concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) | FHH-Chr 8BN/Mcwi | female | 2.4364 | E-7mole | controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) | 56531 | controlled sodium content diet (4 %) (for 21 days) | | phenylephrine (1 umol/l) (for 0.2 hours) | | acetylcholine (0-30 umol/l) | drug dose time series (for 1 hours) |

9 | concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) | FHH-Chr 8BN/Mcwi | male | 5.3688 | E-7mole | controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) | 56543 | controlled sodium content diet (4 %) (for 21 days) | | phenylephrine (1 umol/l) (for 0.2 hours) | | acetylcholine (0-30 umol/l) | drug dose time series (for 1 hours) |

6 | dose of methacholine at which pulmonary conductance is half its pretreatment value | FHH-Chr 8BN/Mcwi | male | 2.9423 | mg/kg | air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) | 58911 | air oxygen content (12 %) (for 14 days) | | methacholine (0-11.06 mg/kg) | drug dose time series (for 0.2 hours) | | |

7 | dose of methacholine at which pulmonary conductance is half its pretreatment value | FHH-Chr 8BN/Mcwi | female | 2.6144 | mg/kg | methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) | 59184 | methacholine (0-11.06 mg/kg) | drug dose time series (for 0.2 hours) | | | | |

8 | dose of methacholine at which pulmonary conductance is half its pretreatment value | FHH-Chr 8BN/Mcwi | male | 5.1409 | mg/kg | methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) | 59196 | methacholine (0-11.06 mg/kg) | drug dose time series (for 0.2 hours) | | | | |

9 | dose of methacholine at which pulmonary conductance is half its pretreatment value | FHH-Chr 8BN/Mcwi | female | 2.275 | mg/kg | air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) | 58907 | air oxygen content (12 %) (for 14 days) | | methacholine (0-11.06 mg/kg) | drug dose time series (for 0.2 hours) | | |

9 | logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) | FHH-Chr 8BN/Mcwi | female | -7.5268 | | phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) | 55286 | phenylephrine (0-300 umol/l) | drug dose time series (for 1.2 hours) | | | | |

10 | logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) | FHH-Chr 8BN/Mcwi | male | -7.9051 | | phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) | 55298 | phenylephrine (0-300 umol/l) | drug dose time series (for 1.2 hours) | | | | |

9 | logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) | FHH-Chr 8BN/Mcwi | female | -7.8689 | | controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) | 56116 | controlled sodium content diet (4 %) (for 21 days) | | phenylephrine (0-300 umol/l) | drug dose time series (for 1.2 hours) | | |

10 | logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) | FHH-Chr 8BN/Mcwi | male | -8.0684 | | controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) | 56128 | controlled sodium content diet (4 %) (for 21 days) | | phenylephrine (0-300 umol/l) | drug dose time series (for 1.2 hours) | | |

10 | acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel | FHH-Chr 8BN/Mcwi | female | 78.8 | % | controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) | 54791 | controlled sodium content diet (4 %) (for 21 days) | | phenylephrine (1 umol/l) (for 0.2 hours) | | acetylcholine (0-30 umol/l) | drug dose time series (for 1 hours) |

9 | acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel | FHH-Chr 8BN/Mcwi | male | 61.7778 | % | controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) | 54803 | controlled sodium content diet (4 %) (for 21 days) | | phenylephrine (1 umol/l) (for 0.2 hours) | | acetylcholine (0-30 umol/l) | drug dose time series (for 1 hours) |

9 | acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel | FHH-Chr 8BN/Mcwi | female | 75.7778 | % | phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) | 57235 | phenylephrine (1 umol/l) (for 0.2 hours) | | acetylcholine (0-30 umol/l) | drug dose time series (for 1 hours) | | |

9 | acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel | FHH-Chr 8BN/Mcwi | male | 76.6667 | % | phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) | 57247 | phenylephrine (1 umol/l) (for 0.2 hours) | | acetylcholine (0-30 umol/l) | drug dose time series (for 1 hours) | | |

9 | logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) | FHH-Chr 8BN/Mcwi | female | -6.8066 | | phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) | 55636 | phenylephrine (1 umol/l) (for 0.2 hours) | | acetylcholine (0-30 umol/l) | drug dose time series (for 1 hours) | | |

9 | logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) | FHH-Chr 8BN/Mcwi | male | -6.9204 | | phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) | 55648 | phenylephrine (1 umol/l) (for 0.2 hours) | | acetylcholine (0-30 umol/l) | drug dose time series (for 1 hours) | | |

10 | logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) | FHH-Chr 8BN/Mcwi | female | -6.8058 | | controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) | 56926 | controlled sodium content diet (4 %) (for 21 days) | | phenylephrine (1 umol/l) (for 0.2 hours) | | acetylcholine (0-30 umol/l) | drug dose time series (for 1 hours) |

9 | logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) | FHH-Chr 8BN/Mcwi | male | -6.6664 | | controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) | 56938 | controlled sodium content diet (4 %) (for 21 days) | | phenylephrine (1 umol/l) (for 0.2 hours) | | acetylcholine (0-30 umol/l) | drug dose time series (for 1 hours) |

9 | concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) | FHH-Chr 8BN/Mcwi | female | 0.0264 | umol/l | phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) | 54685 | phenylephrine (0-300 umol/l) | drug dose time series (for 1.2 hours) | | | | |

10 | concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) | FHH-Chr 8BN/Mcwi | male | 0.0137 | umol/l | phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) | 54697 | phenylephrine (0-300 umol/l) | drug dose time series (for 1.2 hours) | | | | |

9 | concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) | FHH-Chr 8BN/Mcwi | female | 0.0193 | umol/l | controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) | 54917 | controlled sodium content diet (4 %) (for 21 days) | | phenylephrine (0-300 umol/l) | drug dose time series (for 1.2 hours) | | |

10 | concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) | FHH-Chr 8BN/Mcwi | male | 0.0119 | umol/l | controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) | 54929 | controlled sodium content diet (4 %) (for 21 days) | | phenylephrine (0-300 umol/l) | drug dose time series (for 1.2 hours) | | |