SS-Chr 19BN/Mcwi |
left ventricular diastolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
9 |
|
5.72 |
mmHg |
0.4 |
1.21 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49197 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular diastolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
9 |
|
4.97 |
mmHg |
0.18 |
0.54 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49199 |
461 |
SS-Chr 19BN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
female |
49 days-63 days |
10 |
|
20.7 |
% |
2.78 |
8.79 |
digital scale post excision weight measurement |
|
0 |
Moms and pups used in studies were fed Teklad |
49720 |
461 |
SS-Chr 19BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49 days-63 days |
10 |
|
0.36 |
IU/g |
0.06 |
0.2 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47499 |
461 |
SS-Chr 19BN/Mcwi |
time to peak heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
9 |
|
1029.33 |
s |
28.48 |
85.44 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46568 |
461 |
SS-Chr 19BN/Mcwi |
percent change in left ventricular systolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
7 |
post-ischemic value/pre-ischemic value x 100% |
75.9 |
% |
11.78 |
31.17 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48776 |
461 |
SS-Chr 19BN/Mcwi |
arterial blood flow rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
8 |
|
4.96 |
ml/min/g |
0.4 |
1.14 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
44740 |
461 |
SS-Chr 19BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
7 |
|
15.8 |
IU/g |
1.18 |
3.13 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46003 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular diastolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
9 |
|
63.07 |
mmHg |
4.2 |
12.6 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47723 |
461 |
SS-Chr 19BN/Mcwi |
percent change in arterial blood flow rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
8 |
post-ischemic value/pre-ischemic value x 100% |
45.36 |
% |
4.91 |
13.9 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47099 |
461 |
SS-Chr 19BN/Mcwi |
percent change in left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
9 |
post-ischemic value/pre-ischemic value x 100% |
109.38 |
% |
5.61 |
16.82 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
44940 |
461 |
SS-Chr 19BN/Mcwi |
percent change in arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
9 |
post-ischemic value/pre-ischemic value x 100% |
58.82 |
% |
5.59 |
16.77 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46088 |
461 |
SS-Chr 19BN/Mcwi |
heart rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
8 |
|
210.35 |
beats/min |
11.22 |
31.74 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45170 |
461 |
SS-Chr 19BN/Mcwi |
percent change in heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
9 |
post-ischemic value/pre-ischemic value x 100% |
85.4 |
% |
3.17 |
9.51 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48426 |
461 |
SS-Chr 19BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
9 |
|
0.29 |
IU/g |
0.07 |
0.2 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47359 |
461 |
SS-Chr 19BN/Mcwi |
percent change in left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
9 |
post-ischemic value/pre-ischemic value x 100% |
38.68 |
% |
7.02 |
21.05 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46341 |
461 |
SS-Chr 19BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49 days-63 days |
8 |
|
18.39 |
IU/g |
1.31 |
3.72 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46007 |
461 |
SS-Chr 19BN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
male |
49 days-63 days |
8 |
|
25.16 |
% |
3.4 |
9.63 |
digital scale post excision weight measurement |
|
0 |
Moms and pups used in studies were fed Teklad |
49416 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
9 |
|
89.06 |
mmHg |
7.48 |
22.44 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45524 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular systolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
6 |
|
91.82 |
mmHg |
6.4 |
15.68 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49908 |
461 |
SS-Chr 19BN/Mcwi |
percent change in left ventricular developed pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
8 |
post-ischemic value/pre-ischemic value x 100% |
43.56 |
% |
5.71 |
16.16 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48549 |
461 |
SS-Chr 19BN/Mcwi |
arterial blood flow rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
7 |
|
3.38 |
ml/min/g |
0.27 |
0.72 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
44738 |
461 |
SS-Chr 19BN/Mcwi |
arterial blood flow rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
10 |
|
11.87 |
ml/min/g |
0.62 |
1.96 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46675 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
9 |
|
30.78 |
mmHg |
5.48 |
16.45 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47933 |
461 |
SS-Chr 19BN/Mcwi |
heart contraction pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
9 |
|
53.22 |
mmHg |
4.65 |
13.94 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48053 |
461 |
SS-Chr 19BN/Mcwi |
heart contraction pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49 days-63 days |
9 |
|
45.56 |
mmHg |
3.92 |
11.77 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48055 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular diastolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
6 |
|
62.93 |
mmHg |
2.41 |
5.9 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46437 |
461 |
SS-Chr 19BN/Mcwi |
time to onset of heart contraction |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49 days-63 days |
10 |
|
860.7 |
s |
38.26 |
120.99 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49321 |
461 |
SS-Chr 19BN/Mcwi |
heart contraction pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
9 |
|
36.67 |
mmHg |
2.13 |
6.38 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50017 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
9 |
|
83.34 |
mmHg |
7.59 |
22.76 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
|
46770 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
9 |
|
82.34 |
mmHg |
4.51 |
13.52 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
|
46772 |
461 |
SS-Chr 19BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49 days-63 days |
9 |
|
0.29 |
IU/g |
0.06 |
0.19 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47362 |
461 |
SS-Chr 19BN/Mcwi |
percent change in left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
9 |
post-ischemic value/pre-ischemic value x 100% |
125.95 |
% |
10.81 |
32.43 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
44938 |
461 |
SS-Chr 19BN/Mcwi |
heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
9 |
|
281.2 |
beats/min |
12.75 |
38.25 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48217 |
461 |
SS-Chr 19BN/Mcwi |
heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
9 |
|
239.63 |
beats/min |
12.68 |
38.05 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48965 |
461 |
SS-Chr 19BN/Mcwi |
percent change in left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
9 |
post-ischemic value/pre-ischemic value x 100% |
47.2 |
% |
6.3 |
18.9 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46339 |
461 |
SS-Chr 19BN/Mcwi |
heart rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
7 |
|
260.7 |
beats/min |
48.91 |
129.41 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45168 |
461 |
SS-Chr 19BN/Mcwi |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
9 |
|
5.47 |
ml/min/g |
0.5 |
1.5 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46221 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular developed pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
8 |
|
40.09 |
mmHg |
5.31 |
15.02 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45292 |
461 |
SS-Chr 19BN/Mcwi |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
9 |
|
9.59 |
ml/min/g |
0.75 |
2.24 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46890 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular diastolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
8 |
|
55.28 |
mmHg |
4.02 |
11.37 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46439 |
461 |
SS-Chr 19BN/Mcwi |
time to peak heart contraction |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
10 |
|
1084.8 |
s |
39.82 |
125.94 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50249 |
461 |
SS-Chr 19BN/Mcwi |
heart rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
9 |
|
262.16 |
beats/min |
7.61 |
22.83 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47602 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular systolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
8 |
|
95.37 |
mmHg |
4.9 |
13.87 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49910 |
461 |
SS-Chr 19BN/Mcwi |
heart contraction pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49 days-63 days |
10 |
|
34.8 |
mmHg |
2.41 |
7.63 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50019 |
461 |
SS-Chr 19BN/Mcwi |
time to peak heart contraction |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
9 |
|
1103.33 |
s |
36.37 |
109.12 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50247 |
461 |
SS-Chr 19BN/Mcwi |
time to peak heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
9 |
|
1081.22 |
s |
33.59 |
100.78 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
46570 |
461 |
SS-Chr 19BN/Mcwi |
percent change in left ventricular developed pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
7 |
post-ischemic value/pre-ischemic value x 100% |
24.27 |
% |
5.17 |
13.68 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48547 |
461 |
SS-Chr 19BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49 days-63 days |
9 |
|
22.46 |
IU/g |
3.22 |
9.66 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
48905 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular diastolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
9 |
|
69.12 |
mmHg |
4.52 |
13.55 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47721 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular systolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
8 |
|
101.7 |
mmHg |
5.34 |
15.11 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45749 |
461 |
SS-Chr 19BN/Mcwi |
percent change in arterial blood flow rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
7 |
post-ischemic value/pre-ischemic value x 100% |
30.25 |
% |
1.7 |
4.49 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47097 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular diastolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
9 |
|
5.13 |
mmHg |
0.35 |
1.05 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47217 |
461 |
SS-Chr 19BN/Mcwi |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
9 |
|
5.61 |
ml/min/g |
0.32 |
0.96 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46223 |
461 |
SS-Chr 19BN/Mcwi |
arterial blood flow rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
9 |
|
11.35 |
ml/min/g |
0.31 |
0.94 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46673 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
9 |
|
106.28 |
mmHg |
2.92 |
8.77 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
44835 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
9 |
|
37.16 |
mmHg |
4.21 |
12.64 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47931 |
461 |
SS-Chr 19BN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
female |
49 days-63 days |
9 |
|
19.94 |
% |
3.07 |
9.22 |
digital scale post excision weight measurement |
|
0 |
Moms and pups used in studies were fed Teklad |
49418 |
461 |
SS-Chr 19BN/Mcwi |
heart rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
10 |
|
265.92 |
beats/min |
7.32 |
23.15 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47604 |
461 |
SS-Chr 19BN/Mcwi |
time to onset of heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
9 |
|
858.78 |
s |
33.37 |
100.12 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50139 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular developed pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
10 |
|
96.5 |
mmHg |
5.92 |
18.73 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48646 |
461 |
SS-Chr 19BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
9 |
|
23.09 |
IU/g |
2.6 |
7.8 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
48902 |
461 |
SS-Chr 19BN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
male |
49 days-63 days |
9 |
|
18.89 |
% |
2.12 |
6.36 |
digital scale post excision weight measurement |
|
0 |
Moms and pups used in studies were fed Teklad |
49718 |
461 |
SS-Chr 19BN/Mcwi |
time to onset of heart contraction |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
9 |
|
877.0 |
s |
22.7 |
68.09 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
49319 |
461 |
SS-Chr 19BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
9 |
|
0.25 |
IU/g |
0.06 |
0.19 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47495 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
9 |
|
87.31 |
mmHg |
4.48 |
13.43 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45526 |
461 |
SS-Chr 19BN/Mcwi |
percent change in left ventricular systolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
8 |
post-ischemic value/pre-ischemic value x 100% |
96.93 |
% |
6.2 |
17.52 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48778 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular systolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
10 |
|
101.84 |
mmHg |
5.89 |
18.62 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45751 |
461 |
SS-Chr 19BN/Mcwi |
percent change in arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
9 |
post-ischemic value/pre-ischemic value x 100% |
58.82 |
% |
5.72 |
17.15 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46086 |
461 |
SS-Chr 19BN/Mcwi |
heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
9 |
|
263.71 |
beats/min |
10.52 |
31.56 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48219 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
9 |
|
93.85 |
mmHg |
2.92 |
8.77 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
44837 |
461 |
SS-Chr 19BN/Mcwi |
percent change in heart rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
7 |
post-ischemic value/pre-ischemic value x 100% |
100.39 |
% |
17.82 |
47.15 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48315 |
461 |
SS-Chr 19BN/Mcwi |
percent change in heart rate |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
8 |
post-ischemic value/pre-ischemic value x 100% |
80.04 |
% |
3.49 |
9.86 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48317 |
461 |
SS-Chr 19BN/Mcwi |
percent change in heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
8 |
post-ischemic value/pre-ischemic value x 100% |
84.34 |
% |
4.95 |
14.01 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48428 |
461 |
SS-Chr 19BN/Mcwi |
heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
8 |
|
216.22 |
beats/min |
14.24 |
40.27 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48967 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular diastolic blood pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
10 |
|
5.34 |
mmHg |
0.12 |
0.39 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
47219 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular developed pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
6 |
|
28.89 |
mmHg |
5.82 |
14.26 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
45290 |
461 |
SS-Chr 19BN/Mcwi |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
9 |
|
9.96 |
ml/min/g |
0.71 |
2.11 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46892 |
461 |
SS-Chr 19BN/Mcwi |
time to onset of heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49 days-63 days |
9 |
|
868.11 |
s |
25.94 |
77.83 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
50141 |
461 |
SS-Chr 19BN/Mcwi |
left ventricular developed pressure |
air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
8 |
|
96.55 |
mmHg |
5.34 |
15.11 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms and pups used in studies were fed Teklad |
48644 |
461 |