Phenominer Database Results (80 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Duration Post Insult Time Value Experiment Notes Record ID Study ID
FHH-Chr 4BN/Mcwi time to peak heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 9 1215.89 s 50.87 152.6 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46564 461
FHH-Chr 4BN/Mcwi time to peak heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 8 1166.63 s 46.76 132.26 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46566 461
FHH-Chr 4BN/Mcwi percent change in left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 6 post-ischemic value/pre-ischemic value x 100% 35.13 % 5.51 13.51 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48543 461
FHH-Chr 4BN/Mcwi arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 9 5.1 ml/min/g 0.53 1.58 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46217 461
FHH-Chr 4BN/Mcwi percent change in left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 9 post-ischemic value/pre-ischemic value x 100% 111.45 % 8.22 24.65 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 44936 461
FHH-Chr 4BN/Mcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 9 253.56 beats/min 9.69 29.06 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48213 461
FHH-Chr 4BN/Mcwi left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 8 69.71 mmHg 4.04 11.44 balloon tipped catheter with pressure transducer in isolated perfused heart 0 46768 461
FHH-Chr 4BN/Mcwi left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 8 105.21 mmHg 7.47 21.14 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45745 461
FHH-Chr 4BN/Mcwi left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 9 35.33 mmHg 3.82 11.46 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47929 461
FHH-Chr 4BN/Mcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait female 49 days-63 days 8 7.48 % 2.03 5.73 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 49414 461
FHH-Chr 4BN/Mcwi left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 9 76.4 mmHg 3.79 11.38 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45522 461
FHH-Chr 4BN/Mcwi left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 8 5.39 mmHg 0.15 0.43 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49195 461
FHH-Chr 4BN/Mcwi time to peak heart contraction air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 10 1206.1 s 32.33 102.25 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50245 461
FHH-Chr 4BN/Mcwi percent change in left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 8 post-ischemic value/pre-ischemic value x 100% 31.2 % 5.0 14.13 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48545 461
FHH-Chr 4BN/Mcwi arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 9 5.03 ml/min/g 0.48 1.43 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 44736 461
FHH-Chr 4BN/Mcwi left ventricular diastolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 10 5.91 mmHg 0.39 1.23 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47215 461
FHH-Chr 4BN/Mcwi arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 7 4.08 ml/min/g 0.37 0.98 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46219 461
FHH-Chr 4BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 7 0.33 IU/g 0.03 0.08 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47357 461
FHH-Chr 4BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 9 11.57 IU/g 1.63 4.9 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46002 461
FHH-Chr 4BN/Mcwi heart left ventricle infarction weight to total heart left ventricle weight ratio air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait male 49 days-63 days 7 11.42 % 2.47 6.54 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 49714 461
FHH-Chr 4BN/Mcwi left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 8 81.25 mmHg 5.53 15.64 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45520 461
FHH-Chr 4BN/Mcwi heart contraction pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49 days-63 days 8 33.13 mmHg 5.18 14.64 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50013 461
FHH-Chr 4BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 0.24 IU/g 0.05 0.13 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47488 461
FHH-Chr 4BN/Mcwi heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 10 254.35 beats/min 4.66 14.74 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47600 461
FHH-Chr 4BN/Mcwi time to peak heart contraction air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 8 1214.38 s 45.59 128.94 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50243 461
FHH-Chr 4BN/Mcwi left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 10 82.06 mmHg 6.08 19.23 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49906 461
FHH-Chr 4BN/Mcwi heart contraction pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49 days-63 days 10 28.6 mmHg 2.6 8.22 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50015 461
FHH-Chr 4BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 7 0.15 IU/g 0.03 0.07 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47493 461
FHH-Chr 4BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49 days-63 days 8 18.41 IU/g 2.25 6.38 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48901 461
FHH-Chr 4BN/Mcwi left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 9 61.28 mmHg 4.98 14.93 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47717 461
FHH-Chr 4BN/Mcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 9 255.51 beats/min 5.04 15.12 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48215 461
FHH-Chr 4BN/Mcwi heart contraction pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49 days-63 days 9 38.67 mmHg 5.36 16.09 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48049 461
FHH-Chr 4BN/Mcwi percent change in heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 9 post-ischemic value/pre-ischemic value x 100% 92.03 % 3.09 9.28 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48313 461
FHH-Chr 4BN/Mcwi percent change in heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 9 post-ischemic value/pre-ischemic value x 100% 87.11 % 4.44 13.33 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48422 461
FHH-Chr 4BN/Mcwi percent change in arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 8 post-ischemic value/pre-ischemic value x 100% 40.76 % 4.43 12.52 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47093 461
FHH-Chr 4BN/Mcwi left ventricular diastolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 8 5.86 mmHg 0.14 0.41 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47213 461
FHH-Chr 4BN/Mcwi heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 4 214.26 beats/min 17.57 35.14 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45164 461
FHH-Chr 4BN/Mcwi heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 9 233.2 beats/min 9.6 28.81 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45166 461
FHH-Chr 4BN/Mcwi percent change in left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 8 post-ischemic value/pre-ischemic value x 100% 43.32 % 4.62 13.07 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46335 461
FHH-Chr 4BN/Mcwi left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 6 34.45 mmHg 5.96 14.6 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45286 461
FHH-Chr 4BN/Mcwi arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 9 8.18 ml/min/g 0.7 2.1 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46886 461
FHH-Chr 4BN/Mcwi left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 8 32.7 mmHg 4.05 11.46 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47927 461
FHH-Chr 4BN/Mcwi left ventricular diastolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 7 57.65 mmHg 2.97 7.85 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46433 461
FHH-Chr 4BN/Mcwi heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 8 244.54 beats/min 8.59 24.29 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47598 461
FHH-Chr 4BN/Mcwi time to onset of heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49 days-63 days 9 1001.78 s 42.73 128.19 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50135 461
FHH-Chr 4BN/Mcwi time to onset of heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49 days-63 days 9 883.89 s 87.0 260.99 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 50137 461
FHH-Chr 4BN/Mcwi left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 9 5.99 mmHg 0.24 0.73 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49193 461
FHH-Chr 4BN/Mcwi time to onset of heart contraction air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49 days-63 days 8 1000.38 s 34.08 96.4 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49315 461
FHH-Chr 4BN/Mcwi time to onset of heart contraction air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49 days-63 days 10 987.9 s 32.19 101.78 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49317 461
FHH-Chr 4BN/Mcwi percent change in left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 9 post-ischemic value/pre-ischemic value x 100% 83.62 % 5.54 16.62 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48774 461
FHH-Chr 4BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 16.5 IU/g 1.71 5.13 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 48896 461
FHH-Chr 4BN/Mcwi left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 9 106.05 mmHg 8.34 25.03 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45747 461
FHH-Chr 4BN/Mcwi left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 9 48.9 mmHg 4.78 14.34 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 47719 461
FHH-Chr 4BN/Mcwi heart contraction pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49 days-63 days 9 33.11 mmHg 4.06 12.19 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48051 461
FHH-Chr 4BN/Mcwi percent change in arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 9 post-ischemic value/pre-ischemic value x 100% 62.45 % 4.48 13.45 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46082 461
FHH-Chr 4BN/Mcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 9 218.75 beats/min 9.55 28.64 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48961 461
FHH-Chr 4BN/Mcwi percent change in arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 9 post-ischemic value/pre-ischemic value x 100% 43.5 % 3.5 10.51 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47095 461
FHH-Chr 4BN/Mcwi percent change in left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 8 post-ischemic value/pre-ischemic value x 100% 55.04 % 4.8 13.57 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46337 461
FHH-Chr 4BN/Mcwi left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 9 27.33 mmHg 3.79 11.38 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 45288 461
FHH-Chr 4BN/Mcwi left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 8 75.32 mmHg 5.46 15.44 balloon tipped catheter with pressure transducer in isolated perfused heart 0 46766 461
FHH-Chr 4BN/Mcwi arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 7 8.11 ml/min/g 0.65 1.72 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46888 461
FHH-Chr 4BN/Mcwi left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 8 94.78 mmHg 6.35 17.97 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 44831 461
FHH-Chr 4BN/Mcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait male 49 days-63 days 8 11.51 % 3.11 8.81 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 49412 461
FHH-Chr 4BN/Mcwi heart left ventricle infarction weight to total heart left ventricle weight ratio air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait female 49 days-63 days 10 8.47 % 2.05 6.49 digital scale post excision weight measurement 0 Moms and pups used in studies were fed Teklad 49716 461
FHH-Chr 4BN/Mcwi left ventricular diastolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 10 56.79 mmHg 4.56 14.42 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 46435 461
FHH-Chr 4BN/Mcwi left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 8 99.35 mmHg 7.39 20.91 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48640 461
FHH-Chr 4BN/Mcwi left ventricular developed pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 9 100.14 mmHg 8.24 24.72 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48642 461
FHH-Chr 4BN/Mcwi left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 7 88.16 mmHg 9.01 23.84 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 49904 461
FHH-Chr 4BN/Mcwi percent change in left ventricular systolic blood pressure air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 7 post-ischemic value/pre-ischemic value x 100% 85.92 % 7.78 20.58 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48772 461
FHH-Chr 4BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 8 13.64 IU/g 2.07 5.85 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 45997 461
FHH-Chr 4BN/Mcwi arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 8 4.11 ml/min/g 0.41 1.16 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 44734 461
FHH-Chr 4BN/Mcwi percent change in left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49 days-63 days 8 post-ischemic value/pre-ischemic value x 100% 117.55 % 4.86 13.75 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 44934 461
FHH-Chr 4BN/Mcwi percent change in arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 7 post-ischemic value/pre-ischemic value x 100% 51.77 % 5.56 14.72 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46084 461
FHH-Chr 4BN/Mcwi percent change in heart rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49 days-63 days 4 post-ischemic value/pre-ischemic value x 100% 91.74 % 9.9 19.79 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48311 461
FHH-Chr 4BN/Mcwi percent change in heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 8 post-ischemic value/pre-ischemic value x 100% 84.95 % 4.3 12.17 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48424 461
FHH-Chr 4BN/Mcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49 days-63 days 9 0.31 IU/g 0.03 0.08 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 47352 461
FHH-Chr 4BN/Mcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49 days-63 days 8 214.4 beats/min 11.87 33.57 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 48963 461
FHH-Chr 4BN/Mcwi arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait male 49 days-63 days 8 10.26 ml/min/g 0.6 1.7 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46669 461
FHH-Chr 4BN/Mcwi arterial blood flow rate air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait female 49 days-63 days 10 11.71 ml/min/g 0.45 1.44 isolated perfused heart effluent collection 0 Moms and pups used in studies were fed Teklad 46671 461
FHH-Chr 4BN/Mcwi left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49 days-63 days 9 84.22 mmHg 6.05 18.16 balloon tipped catheter with pressure transducer in isolated perfused heart 0 Moms and pups used in studies were fed Teklad 44833 461