FHH-Chr 17BN/Mcwi |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
10 |
67.0 |
% |
6.65 |
21.03 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
54780 |
522 |
FHH-Chr 17BN/Mcwi |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
9 |
87.0 |
% |
6.0 |
18.01 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
57227 |
522 |
FHH-Chr 17BN/Mcwi |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
9 |
-6.93 |
null |
0.08 |
0.23 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
55628 |
522 |
FHH-Chr 17BN/Mcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
10 |
1.03 |
E-7mole |
0.19 |
0.58 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
55894 |
522 |
FHH-Chr 17BN/Mcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
10 |
3.36 |
E-7mole |
2.05 |
6.49 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56520 |
522 |
FHH-Chr 17BN/Mcwi |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
10 |
-6.87 |
null |
0.04 |
0.12 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56915 |
522 |
FHH-Chr 17BN/Mcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
9 |
1.2 |
E-7mole |
0.35 |
1.05 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
55897 |
522 |
FHH-Chr 17BN/Mcwi |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
9 |
88.44 |
% |
4.26 |
12.77 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
57224 |
522 |
FHH-Chr 17BN/Mcwi |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
10 |
-6.86 |
null |
0.06 |
0.18 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56918 |
522 |
FHH-Chr 17BN/Mcwi |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
10 |
86.0 |
% |
3.59 |
11.34 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
54783 |
522 |
FHH-Chr 17BN/Mcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
10 |
1.48 |
E-7mole |
0.19 |
0.61 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56523 |
522 |
FHH-Chr 17BN/Mcwi |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
10 |
-7.03 |
null |
0.06 |
0.19 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
55625 |
522 |