SS-Chr 18BN/Mcwi |
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
10 |
-8.02 |
null |
0.04 |
0.13 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Dyets |
55998 |
522 |
SS-Chr 18BN/Mcwi |
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
8 |
-8.22 |
null |
0.05 |
0.14 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Dyets |
56003 |
522 |
SS-Chr 18BN/Mcwi |
concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
10 |
0.06 |
10E-7mol/l |
0.01 |
0.02 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Dyets |
56263 |
522 |
SS-Chr 18BN/Mcwi |
concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
10 |
0.06 |
10E-7mol/l |
0.01 |
0.03 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Dyets |
56258 |
522 |
SS-Chr 18BN/Mcwi |
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
10 |
99.4 |
% |
0.6 |
1.9 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56317 |
522 |
SS-Chr 18BN/Mcwi |
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
10 |
100.0 |
% |
0.0 |
0.0 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Dyets |
56192 |
522 |
SS-Chr 18BN/Mcwi |
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
9 |
-8.05 |
null |
0.09 |
0.27 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56034 |
522 |
SS-Chr 18BN/Mcwi |
concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
10 |
0.1 |
10E-7mol/l |
0.01 |
0.03 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Dyets |
56691 |
522 |
SS-Chr 18BN/Mcwi |
concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
8 |
0.06 |
10E-7mol/l |
0.01 |
0.02 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Dyets |
56696 |
522 |
SS-Chr 18BN/Mcwi |
concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
10 |
0.2 |
10E-7mol/l |
0.03 |
0.08 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56242 |
522 |
SS-Chr 18BN/Mcwi |
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
10 |
-7.73 |
null |
0.07 |
0.21 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56030 |
522 |
SS-Chr 18BN/Mcwi |
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
10 |
99.7 |
% |
0.3 |
0.95 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Dyets |
56197 |
522 |
SS-Chr 18BN/Mcwi |
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
9 |
99.33 |
% |
0.37 |
1.12 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56321 |
522 |
SS-Chr 18BN/Mcwi |
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
10 |
-8.3 |
null |
0.06 |
0.2 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Dyets |
55488 |
522 |
SS-Chr 18BN/Mcwi |
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
10 |
-8.31 |
null |
0.08 |
0.24 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Dyets |
55483 |
522 |
SS-Chr 18BN/Mcwi |
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
10 |
99.4 |
% |
0.34 |
1.08 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Dyets |
55963 |
522 |
SS-Chr 18BN/Mcwi |
concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
9 |
0.11 |
10E-7mol/l |
0.02 |
0.07 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56246 |
522 |
SS-Chr 18BN/Mcwi |
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
10 |
98.5 |
% |
0.34 |
1.08 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Dyets |
55968 |
522 |