Phenominer Database Results (72 results)

 

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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Time Value Post Insult Time Unit Record ID Study ID
GK/Jpe blood glucose level controlled cholesterol content diet (1.25 %) (for 90 days) and controlled cocoa butter content diet (7.5 %) (for 90 days) then soybean oil (2 ml/kg) then fasting (for 15 hours) Sena CM, etal., Br J Pharmacol. 2008 Mar;153(5):894-906. doi: 10.1038/sj.bjp.0707474. Epub 2007 Oct 1. blood glucose amount male 540 days 10 129.6 mg/dl 4.5 14.23 blood glucose test strip read by electrochemical glucometer 0.0 0 108007 3108
GK/Jpe blood glucose level controlled cholesterol content diet (1.25 %) (for 90 days) and controlled cocoa butter content diet (7.5 %) (for 90 days) then lipoic acid (50 mg/kg) then fasting (for 15 hours) then glucose solution (1.75 g/kg) (for 2 hours) Sena CM, etal., Br J Pharmacol. 2008 Mar;153(5):894-906. doi: 10.1038/sj.bjp.0707474. Epub 2007 Oct 1. blood glucose amount male 540 days 10 365.6 mg/dl 9.5 30.04 intraperitoneal glucose tolerance test 0.0 120 min 108013 3108
GK/Jpe serum triglyceride level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood triglyceride amount male 540 days 7 551.33 mg/dl 84.96 224.77 colorimetry 0.0 0 110882 3193
GK/Jpe serum albumin level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood albumin amount male 540 days 7 2.6 g/dl 0.04 0.11 blood protein analysis 0.0 0 110887 3193
GK/Jpe blood glucose level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood glucose amount male 540 days 7 151.56 mg/dl 7.2 19.05 blood glucose test strip read by electrochemical glucometer 0.0 0 110862 3193
GK/Jpe blood glucose level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and soybean oil (2 ml/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood glucose amount male 540 days 7 129.42 mg/dl 5.4 14.29 blood glucose test strip read by electrochemical glucometer 0.0 0 110863 3193
GK/Jpe hepatic extraction fraction fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. xenobiotic pharmacokinetics trait male 540 days 7 100.0 % 1.5 3.97 scintigraphy 0.0 0 110917 3193
GK/Jpe urine 8-hydroxy-2'-deoxyguanosine level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and soybean oil (2 ml/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. urine molecular composition trait male 540 days 7 302.37 ng/d 42.34 112.02 enzyme linked immunosorbent assay 0.0 0 110929 3193
GK/Jpe serum uric acid level fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood uric acid amount male 540 days 7 0.03 umol/l 0.0 0.01 blood uric acid analysis 0.0 0 110932 3193
GK/Jpe serum uric acid level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood uric acid amount male 540 days 7 0.03 umol/l 0.0 0.01 blood uric acid analysis 0.0 0 110933 3193
GK/Jpe blood glucose level fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood glucose amount male 540 days 7 115.02 mg/dl 7.2 19.05 blood glucose test strip read by electrochemical glucometer 0.0 0 110846 3193
GK/Jpe blood glucose level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) then fasting (for 15 hours) then glucose solution (1.75 g/kg) (for 2 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood glucose amount male 540 days 7 418.68 mg/dl 28.8 76.2 intraperitoneal glucose tolerance test 0.0 0 110867 3193
GK/Jpe blood glucose level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and soybean oil (2 ml/kg) (for 90 days) then fasting (for 15 hours) then glucose solution (1.75 g/kg) (for 2 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood glucose amount male 540 days 7 358.2 mg/dl 14.4 38.1 intraperitoneal glucose tolerance test 0.0 0 110868 3193
GK/Jpe blood glucose level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and lipoic acid (50 mg/kg) then fasting (for 15 hours) then glucose solution (1.75 g/kg) (for 2 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood glucose amount male 540 days 7 363.6 mg/dl 9.0 23.81 intraperitoneal glucose tolerance test 0.0 0 110869 3193
GK/Jpe serum aspartate aminotransferase activity level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood aspartate transaminase amount male 540 days 7 176.0 U/l 7.4 19.58 blood enzyme activity assay 0.0 0 110897 3193
GK/Jpe serum aspartate aminotransferase activity level fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood aspartate transaminase amount male 540 days 7 178.0 U/l 15.1 39.95 blood enzyme activity assay 0.0 0 110896 3193
GK/Jpe serum gamma-glutamyltransferase activity level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and soybean oil (2 ml/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood gamma-glutamyltransferase amount male 540 days 7 1.6 U/l 0.2 0.53 blood enzyme activity assay 0.0 0 110914 3193
GK/Jpe serum triglyceride level fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood triglyceride amount male 540 days 7 160.18 mg/dl 69.03 182.63 colorimetry 0.0 0 110881 3193
GK/Jpe blood glucose level controlled cholesterol content diet (1.25 %) (for 90 days) and controlled cocoa butter content diet (7.5 %) (for 90 days) then fasting (for 15 hours) then glucose solution (1.75 g/kg) (for 2 hours) Sena CM, etal., Br J Pharmacol. 2008 Mar;153(5):894-906. doi: 10.1038/sj.bjp.0707474. Epub 2007 Oct 1. blood glucose amount male 540 days 10 419.1 mg/dl 28.5 90.12 intraperitoneal glucose tolerance test 0.0 120 min 108011 3108
GK/Jpe blood glucose level controlled cholesterol content diet (1.25 %) (for 90 days) and controlled cocoa butter content diet (7.5 g/kg) (for 90 days) then soybean oil (2 ml/kg) then fasting (2 ml/kg) (for 15 hours) then glucose solution (1.75 g/kg) (for 2 hours) Sena CM, etal., Br J Pharmacol. 2008 Mar;153(5):894-906. doi: 10.1038/sj.bjp.0707474. Epub 2007 Oct 1. blood glucose amount male 540 days 10 338.6 mg/dl 23.4 74.0 intraperitoneal glucose tolerance test 0.0 120 min 108012 3108
GK/Jpe serum albumin level fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood albumin amount male 540 days 7 2.9 g/dl 0.1 0.26 blood protein analysis 0.0 0 110886 3193
GK/Jpe serum albumin level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and lipoic acid (50 mg/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood albumin amount male 540 days 7 2.4 g/dl 0.04 0.11 blood protein analysis 0.0 0 110889 3193
GK/Jpe plasma malondialdehyde level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood malondialdehyde amount male 540 days 7 1.8 umol/l 0.1 0.26 high-performance liquid chromatography 0.0 0 110923 3193
GK/Jpe urine 8-hydroxy-2'-deoxyguanosine level fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. urine molecular composition trait male 540 days 7 306.57 ng/d 23.76 62.86 enzyme linked immunosorbent assay 0.0 0 110927 3193
GK/Jpe urine 8-hydroxy-2'-deoxyguanosine level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and lipoic acid (50 mg/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. urine molecular composition trait male 540 days 7 5.63 ng/d 0.36 0.95 enzyme linked immunosorbent assay 0.0 0 110930 3193
GK/Jpe hepatic extraction fraction controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. xenobiotic pharmacokinetics trait male 540 days 7 87.0 % 2.9 7.67 scintigraphy 0.0 0 110918 3193
GK/Jpe hepatic extraction fraction controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and soybean oil (2 ml/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. xenobiotic pharmacokinetics trait male 540 days 7 94.6 % 1.8 4.76 scintigraphy 0.0 0 110919 3193
GK/Jpe serum aspartate aminotransferase activity level to alanine aminotransferase activity level ratio fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood aspartate transaminase amount male 540 days 7 3.9 null 0.1 0.26 blood enzyme activity assay 0.0 0 110936 3193
GK/Jpe serum total bilirubin level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and lipoic acid (50 mg/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood bilirubin amount male 540 days 7 0.18 mg/dl 0.02 0.05 ex vivo blood analysis 0.0 0 110894 3193
GK/Jpe serum alanine aminotransferase activity level fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood alanine transaminase amount male 540 days 7 43.6 U/l 1.1 2.91 blood enzyme activity assay 0.0 0 110901 3193
GK/Jpe serum alanine aminotransferase activity level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and lipoic acid (50 mg/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood alanine transaminase amount male 540 days 7 37.5 U/l 1.3 3.44 blood enzyme activity assay 0.0 0 110904 3193
GK/Jpe blood glucose level fasting (for 15 hours) then glucose solution (1.75 g/kg) (for 2 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood glucose amount male 540 days 7 332.1 mg/dl 48.6 128.58 intraperitoneal glucose tolerance test 0.0 0 110866 3193
GK/Jpe serum alkaline phosphatase activity level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood alkaline phosphatase amount male 540 days 7 157.3 U/l 9.8 25.93 blood enzyme activity assay 0.0 0 110908 3193
GK/Jpe serum aspartate aminotransferase activity level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and soybean oil (2 ml/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood aspartate transaminase amount male 540 days 7 154.0 U/l 12.4 32.81 blood enzyme activity assay 0.0 0 110898 3193
GK/Jpe serum aspartate aminotransferase activity level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and lipoic acid (50 mg/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood aspartate transaminase amount male 540 days 7 151.0 U/l 8.7 23.02 blood enzyme activity assay 0.0 0 110899 3193
GK/Jpe serum triglyceride level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and lipoic acid (50 mg/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood triglyceride amount male 540 days 7 116.81 mg/dl 14.16 37.46 colorimetry 0.0 0 110884 3193
GK/Jpe serum albumin level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and soybean oil (2 ml/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood albumin amount male 540 days 7 2.7 g/dl 0.06 0.16 blood protein analysis 0.0 0 110888 3193
GK/Jpe blood glucose level control condition then fasting (for 15 hours) Sena CM, etal., Br J Pharmacol. 2008 Mar;153(5):894-906. doi: 10.1038/sj.bjp.0707474. Epub 2007 Oct 1. blood glucose amount male 540 days 20 115.3 mg/dl 5.6 25.04 blood glucose test strip read by electrochemical glucometer 0.0 0 108005 3108
GK/Jpe blood glucose level controlled cholesterol content diet (1.25 %) (for 90 days) and controlled cocoa butter content diet (7.5 %) (for 90 days) then lipoic acid (50 mg/kg) then fasting (for 15 hours) Sena CM, etal., Br J Pharmacol. 2008 Mar;153(5):894-906. doi: 10.1038/sj.bjp.0707474. Epub 2007 Oct 1. blood glucose amount male 540 days 10 122.3 mg/dl 9.3 29.41 blood glucose test strip read by electrochemical glucometer 0.0 0 108008 3108
GK/Jpe blood glucose level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and lipoic acid (50 mg/kg) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood glucose amount male 540 days 7 122.04 mg/dl 5.4 14.29 blood glucose test strip read by electrochemical glucometer 0.0 0 110864 3193
GK/Jpe plasma malondialdehyde level fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood malondialdehyde amount male 540 days 7 1.5 umol/l 0.1 0.26 high-performance liquid chromatography 0.0 0 110922 3193
GK/Jpe serum total bilirubin level fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood bilirubin amount male 540 days 7 0.16 mg/dl 0.0 0.0 ex vivo blood analysis 0.0 0 110891 3193
GK/Jpe serum alanine aminotransferase activity level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood alanine transaminase amount male 540 days 7 40.1 U/l 4.3 11.38 blood enzyme activity assay 0.0 0 110902 3193
GK/Jpe serum gamma-glutamyltransferase activity level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood gamma-glutamyltransferase amount male 540 days 7 1.9 U/l 0.1 0.26 blood enzyme activity assay 0.0 0 110913 3193
GK/Jpe serum total cholesterol level fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood cholesterol amount male 540 days 7 154.44 mg/dl 25.48 67.42 colorimetry 0.0 0 110871 3193
GK/Jpe serum non-high density lipoprotein cholesterol level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and lipoic acid (50 mg/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood cholesterol amount male 540 days 7 1.11 mmol/l 0.16 0.42 colorimetry 0.0 0 110879 3193
GK/Jpe serum triglyceride level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and soybean oil (2 ml/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood triglyceride amount male 540 days 7 196.46 mg/dl 37.17 98.34 colorimetry 0.0 0 110883 3193
GK/Jpe serum total bilirubin level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and soybean oil (2 ml/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood bilirubin amount male 540 days 7 0.14 mg/dl 0.04 0.11 ex vivo blood analysis 0.0 0 110893 3193
GK/Jpe blood glucose level controlled cholesterol content diet (1.25 %) (for 90 days) and controlled cocoa butter content diet (7.5 %) (for 90 days) then fasting (between 15 and 0.2 hours) Sena CM, etal., Br J Pharmacol. 2008 Mar;153(5):894-906. doi: 10.1038/sj.bjp.0707474. Epub 2007 Oct 1. blood glucose amount male 540 days 10 151.7 mg/dl 7.9 24.98 blood glucose test strip read by electrochemical glucometer 0.0 0 108006 3108
GK/Jpe serum alanine aminotransferase activity level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and soybean oil (2 ml/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood alanine transaminase amount male 540 days 7 27.0 U/l 2.0 5.29 blood enzyme activity assay 0.0 0 110903 3193
GK/Jpe serum alkaline phosphatase activity level fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood alkaline phosphatase amount male 540 days 7 137.1 U/l 10.5 27.78 blood enzyme activity assay 0.0 0 110907 3193
GK/Jpe serum alkaline phosphatase activity level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and lipoic acid (50 mg/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood alkaline phosphatase amount male 540 days 7 125.2 U/l 7.4 19.58 blood enzyme activity assay 0.0 0 110910 3193
GK/Jpe serum gamma-glutamyltransferase activity level fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood gamma-glutamyltransferase amount male 540 days 7 2.1 U/l 0.1 0.26 blood enzyme activity assay 0.0 0 110912 3193
GK/Jpe plasma malondialdehyde level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and lipoic acid (50 mg/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood malondialdehyde amount male 540 days 7 1.11 umol/l 0.1 0.26 high-performance liquid chromatography 0.0 0 110925 3193
GK/Jpe plasma malondialdehyde level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and soybean oil (2 ml/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood malondialdehyde amount male 540 days 7 1.42 umol/l 0.2 0.53 high-performance liquid chromatography 0.0 0 110924 3193
GK/Jpe serum aspartate aminotransferase activity level to alanine aminotransferase activity level ratio controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood aspartate transaminase amount male 540 days 7 4.2 null 0.2 0.53 blood enzyme activity assay 0.0 0 110937 3193
GK/Jpe serum aspartate aminotransferase activity level to alanine aminotransferase activity level ratio controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and soybean oil (2 ml/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood aspartate transaminase amount male 540 days 7 5.7 null 0.4 1.06 blood enzyme activity assay 0.0 0 110938 3193
GK/Jpe serum alkaline phosphatase activity level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and soybean oil (2 ml/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood alkaline phosphatase amount male 540 days 7 114.8 U/l 7.8 20.64 blood enzyme activity assay 0.0 0 110909 3193
GK/Jpe serum total cholesterol level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood cholesterol amount male 540 days 7 705.4 mg/dl 118.15 312.59 colorimetry 0.0 0 110872 3193
GK/Jpe serum total cholesterol level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and soybean oil (2 ml/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood cholesterol amount male 540 days 7 145.56 mg/dl 21.62 57.21 colorimetry 0.0 0 110873 3193
GK/Jpe serum non-high density lipoprotein cholesterol level fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood cholesterol amount male 540 days 7 1.76 mmol/l 0.51 1.35 colorimetry 0.0 0 110876 3193
GK/Jpe serum non-high density lipoprotein cholesterol level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and soybean oil (2 ml/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood cholesterol amount male 540 days 7 2.23 mmol/l 0.48 1.27 colorimetry 0.0 0 110878 3193
GK/Jpe serum gamma-glutamyltransferase activity level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and lipoic acid (50 mg/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood gamma-glutamyltransferase amount male 540 days 7 1.3 U/l 0.2 0.53 blood enzyme activity assay 0.0 0 110915 3193
GK/Jpe blood glucose level fasting (for 15 hours) then glucose solution (1.75 g/kg) (for 2 hours) Sena CM, etal., Br J Pharmacol. 2008 Mar;153(5):894-906. doi: 10.1038/sj.bjp.0707474. Epub 2007 Oct 1. blood glucose amount male 540 days 20 332.5 mg/dl 47.7 213.32 intraperitoneal glucose tolerance test 0.0 120 min 108010 3108
GK/Jpe urine 8-hydroxy-2'-deoxyguanosine level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. urine molecular composition trait male 540 days 7 415.8 ng/d 74.29 196.55 enzyme linked immunosorbent assay 0.0 0 110928 3193
GK/Jpe hepatic extraction fraction controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and lipoic acid (50 mg/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. xenobiotic pharmacokinetics trait male 540 days 7 97.8 % 1.74 4.6 scintigraphy 0.0 0 110920 3193
GK/Jpe serum uric acid level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and soybean oil (2 ml/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood uric acid amount male 540 days 7 0.03 umol/l 0.0 0.01 blood uric acid analysis 0.0 0 110934 3193
GK/Jpe serum uric acid level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and lipoic acid (50 mg/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood uric acid amount male 540 days 7 0.02 umol/l 0.0 0.0 blood uric acid analysis 0.0 0 110935 3193
GK/Jpe serum aspartate aminotransferase activity level to alanine aminotransferase activity level ratio controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and lipoic acid (50 mg/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood aspartate transaminase amount male 540 days 7 3.9 null 0.2 0.53 blood enzyme activity assay 0.0 0 110940 3193
GK/Jpe serum total cholesterol level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) and lipoic acid (50 mg/kg) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood cholesterol amount male 540 days 7 92.28 mg/dl 10.42 27.58 colorimetry 0.0 0 110874 3193
GK/Jpe serum total bilirubin level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood bilirubin amount male 540 days 7 0.14 mg/dl 0.02 0.05 ex vivo blood analysis 0.0 0 110892 3193
GK/Jpe serum total cholesterol level controlled cocoa butter content diet (7.5 %) (for 90 days) and controlled cholesterol content diet (1.25 %) (for 90 days) then fasting (for 15 hours) Sena CM, etal., Int J Mol Sci. 2018 Sep 11;19(9). pii: ijms19092706. doi: 10.3390/ijms19092706. blood cholesterol amount male 540 days 7 618.15 mg/dl 115.83 306.46 colorimetry 0.0 0 110877 3193