Phenominer Database Results (11 results)

 

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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Average Type Value Units SEM SD Method Method Site Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Record ID Study ID
SHRSP/A3N kidney weight controlled sodium chloride content drinking water (1 %) (between 42 and 77 days) and controlled fat content diet (24.5 %) (between 42 and 77 days) and vehicle control condition (between 42 and 77 days) Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. kidney mass male 126 days-182 days 0 2.65 g 0.1 post excision weight measurement kidney 0.0 0 107531 3090
SHRSP/A3N kidney glomerular lesion count controlled sodium chloride content drinking water (1 %) (between 42 and 77 days) and controlled fat content diet (24.5 %) (between 42 and 77 days) and vehicle control condition (between 42 and 77 days) Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. kidney glomerulus integrity trait male 126 days-182 days 0 76.5 /section 7.0 ex vivo light microscopy with histochemistry renal glomerulus 0.0 0 107539 3090
SHRSP/A3N body weight controlled sodium chloride content drinking water (1 %) (for 42 days) and controlled fat content diet (24.5 %) (for 42 days) and vehicle control condition (for 42 days) Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. body mass male 126 days-147 days 0 254.0 g 7.0 body weighing method 0.0 0 107527 3090
SHRSP/A3N kidney total tubule cast count controlled sodium chloride content drinking water (1 %) (between 42 and 77 days) and controlled fat content diet (24.5 %) (between 42 and 77 days) and vehicle control condition (between 42 and 77 days) Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. kidney integrity trait male 126 days-182 days 0 349.0 /section 45.0 ex vivo light microscopy with histochemistry 0.0 0 107555 3090
SHRSP/A3N renal fibrosis foci count controlled sodium chloride content drinking water (1 %) (between 42 and 77 days) and controlled fat content diet (24.5 %) (between 42 and 77 days) and vehicle control condition (between 42 and 77 days) Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. kidney integrity trait male 126 days-182 days 0 16.4 /section 1.4 ex vivo light microscopy with histochemistry 0.0 0 107559 3090
SHRSP/A3N interstitial nephritis foci count controlled sodium chloride content drinking water (1 %) (between 42 and 77 days) and controlled fat content diet (24.5 %) (between 42 and 77 days) and vehicle control condition (between 42 and 77 days) Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. kidney integrity trait male 126 days-182 days 0 8.5 /section 1.2 ex vivo light microscopy with histochemistry 0.0 0 107551 3090
SHRSP/A3N systolic blood pressure controlled sodium chloride content drinking water (1 %) (for 84 days) and controlled fat content diet (24.5 %) (for 84 days) and vehicle control condition (for 84 days) Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. arterial blood pressure trait male 168 days-189 days 6 serial mean 284.0 mmHg 8.0 19.6 tail cuff plethysmography tail 0.0 0 average 3 week intervals for 12 weeks 107499 3090
SHRSP/A3N kidney tubule regeneration foci count controlled sodium chloride content drinking water (1 %) (between 42 and 77 days) and controlled fat content diet (24.5 %) (between 42 and 77 days) and vehicle control condition (between 42 and 77 days) Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. kidney integrity trait male 126 days-182 days 0 27.3 /section 2.9 ex vivo light microscopy with histochemistry 0.0 0 107547 3090
SHRSP/A3N ratio of deaths related to chronic hypertension to total study population during a period of time controlled sodium chloride content drinking water (1 %) (for 63 days) and controlled fat content diet (24.5 %) (for 63 days) and vehicle control condition (for 63 days) Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. total life span male 147 days-168 days 25 95.0 % unspecified method 0.0 0 ratio of deaths related to chronic hypertension to total study population during a period of time (CMO:0003800) 107518 3090
SHRSP/A3N urine total protein excretion rate controlled sodium chloride content drinking water (1 %) (between 35 and 49 days) and controlled fat content diet (24.5 %) (between 35 and 49 days) and vehicle control condition (between 35 and 49 days) Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. total urine protein amount male 119 days-154 days 0 127.0 mg/d 13.0 urine protein analysis 86400.0 0 107520 3090
SHRSP/A3N both kidneys wet weight to body weight ratio controlled sodium chloride content drinking water (1 %) (between 42 and 77 days) and controlled fat content diet (24.5 %) (between 42 and 77 days) and vehicle control condition (between 42 and 77 days) Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. kidney mass male 126 days-182 days 0 13.0 g/kg 0.7 post excision weight measurement kidney 0.0 0 107535 3090