Phenominer Database Results (142 results)

 

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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Experiment Notes Record ID Study ID
GK/MolTac ejection fraction control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. cardiac output trait male 112 days 8 66.0 % 11.0 31.11 vascular transducer tipped catheter 0.0 0 102963 2783
GK/MolTac stroke volume control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. cardiac output trait male 112 days 8 65000.0 ml 11000.0 31112.7 vascular transducer tipped catheter 0.0 0 102969 2783
GK/MolTac blood hemoglobin level control condition (between 70 and 77 days) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood hemoglobin amount male 70 days-77 days 7 15.8 g/dl 0.34 0.9 automated hematology analysis 0.0 0 103851 2864
GK/MolTac hematocrit rosiglitazone (5 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. erythrocyte quantity male 122 days-129 days 5 53.4 % 1.25 2.8 automated hematology analysis 0.0 0 103870 2864
GK/MolTac hematocrit sodium chloride solution (for 23 days) then control condition (for 60 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. erythrocyte quantity male 164 days-171 days 7 58.1 % 0.6 1.6 automated hematology analysis 0.0 0 103872 2864
GK/MolTac hematocrit rosiglitazone (5 mg/kg) (for 23 days) then control condition (for 60 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. erythrocyte quantity male 164 days-171 days 7 54.8 % 1.85 4.9 automated hematology analysis 0.0 0 103873 2864
GK/MolTac blood hemoglobin A1c level control condition (between 70 and 77 days) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood hemoglobin amount male 70 days-77 days 7 4.94 % 0.09 0.24 automated hematology analysis 0.0 0 103875 2864
GK/MolTac blood hemoglobin A1c level sodium chloride solution (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood hemoglobin amount male 122 days-129 days 7 5.41 % 0.08 0.22 automated hematology analysis 0.0 0 103881 2864
GK/MolTac blood hemoglobin A1c level sodium chloride solution (for 23 days) then control condition (for 60 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood hemoglobin amount male 164 days-171 days 7 6.89 % 0.61 1.61 automated hematology analysis 0.0 0 103884 2864
GK/MolTac whole body insulin sensitivity index rosiglitazone (10 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood insulin amount male 122 days-129 days 4 10,000/√(FG x FI) x (Ḡ x Ī) 2.04 null 0.21 0.42 oral glucose tolerance test 7200.0 0 measured at -5,15,30,45,60,90,120 min 103831 2864
GK/MolTac maximum rate of negative change in left ventricular blood pressure control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. heart left ventricular blood pressure trait male 112 days 8 -12940.0 mmHg/s 1112.0 3145.21 vascular transducer tipped catheter 0.0 0 102979 2783
GK/MolTac time constant of left ventricular pressure decay control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. heart left ventricular blood pressure trait male 112 days 8 8.15 ms 0.19 0.54 vascular transducer tipped catheter 0.0 0 102981 2783
GK/MolTac heart left ventricle weight to body weight ratio control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. heart left ventricle mass male 112 days 8 3.41 mg/g 0.17 0.48 echocardiography 0.0 0 102990 2783
GK/MolTac blood glucose level control condition Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. blood glucose amount male 144 days 6 382.0 mg/dl 69.0 169.01 blood glucose analysis 0.0 0 103990 2885
GK/MolTac plasma insulin level rosiglitazone (5 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood insulin amount male 122 days-129 days 4 38.22 mU/l 5.2 10.4 oral glucose tolerance test 0.0 0 103816 2864
GK/MolTac blood insulin level control condition then controlled saxagliptin content diet (10 mg/kg/d) (for 12 days) Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. blood insulin amount male 147 days 12 71.47 mU/l 8.24 28.53 blood insulin analysis 0.0 0 104003 2885
GK/MolTac blood dipeptidyl peptidase 4 activity level control condition then controlled saxagliptin content diet (10 mg/kg/d) (for 12 days) Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. blood enzyme amount male 147 days 0 35.0 pmol/min 14.0 blood enzyme activity assay 0.0 0 104011 2885
GK/MolTac body weight control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. body mass female 60 days 6 209.0 g 6.0 14.7 body weighing method 0.0 0 body weight 106893 3071
GK/MolTac body weight control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. body mass female 420 days 11 292.0 g 6.0 19.9 body weighing method 0.0 0 body weight 106895 3071
GK/MolTac serum insulin level control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. blood insulin amount female 60 days 6 0.0 mg/dl 0.0 0.0 enzyme linked immunosorbent assay 0.0 0 fasting insulin, non fasting insulin 106917 3071
GK/MolTac body weight control condition Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. body mass male 105 days 8 325.4 g 9.2 26.02 body weighing method 0.0 0 110729 3183
GK/MolTac serum insulin level control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. blood insulin amount male 112 days 8 0.0 mg/dl 0.0 0.0 enzyme linked immunosorbent assay 0.0 0 102943 2783
GK/MolTac mean arterial blood pressure control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. arterial blood pressure trait male 112 days 8 104.0 mmHg 5.0 14.14 vascular transducer tipped catheter 0.0 0 102961 2783
GK/MolTac red blood cell count control condition (between 70 and 77 days) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. erythrocyte quantity male 70 days-77 days 7 7.2 x 10E6 cells/ul 0.3 0.8 automated blood cell counting method 0.0 0 103841 2864
GK/MolTac diastolic blood pressure control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. arterial blood pressure trait male 112 days 8 93.0 mmHg 5.0 14.14 vascular transducer tipped catheter 0.0 0 102959 2783
GK/MolTac cardiac output control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. cardiac output trait male 112 days 8 32.0 ml/min 6.0 16.97 vascular transducer tipped catheter 0.0 0 102965 2783
GK/MolTac cardiac index control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. cardiac output trait male 112 days 8 97.0 ml/min/g 21.0 59.4 vascular transducer tipped catheter 0.0 0 102967 2783
GK/MolTac stroke index control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. cardiac output trait male 112 days 8 0.2 ul/g 0.04 0.11 vascular transducer tipped catheter 0.0 0 102971 2783
GK/MolTac systemic vascular resistance control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. arterial blood flow trait male 112 days 8 2.49 mmHg/ml/min 0.23 0.65 vascular transducer tipped catheter 0.0 0 102975 2783
GK/MolTac red blood cell count rosiglitazone (10 mg/kg) (for 23 days) then control condition (for 60 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. erythrocyte quantity male 164 days-171 days 7 9.8 x 10E6 cells/ul 0.04 0.1 automated blood cell counting method 0.0 0 103850 2864
GK/MolTac blood hemoglobin level sodium chloride solution (for 23 days) then control condition (for 60 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood hemoglobin amount male 164 days-171 days 7 17.9 g/dl 0.15 0.4 automated hematology analysis 0.0 0 103860 2864
GK/MolTac hematocrit rosiglitazone (10 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. erythrocyte quantity male 122 days-129 days 7 54.1 % 0.83 2.2 automated hematology analysis 0.0 0 103871 2864
GK/MolTac red blood cell count sodium chloride solution (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. erythrocyte quantity male 122 days-129 days 7 9.0 x 10E6 cells/ul 0.26 0.7 automated blood cell counting method 0.0 0 103845 2864
GK/MolTac Homeostatic Model Assessment of Insulin Resistance rosiglitazone (5 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood insulin amount male 122 days-129 days 4 (fasting glucose x fasting insulin)/22.5 14.2 null 2.15 4.3 oral glucose tolerance test 7200.0 0 103837 2864
GK/MolTac blood glucose level rosiglitazone (5 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 16 hours) then glucose solution (2 g/kg) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood glucose amount male 122 days-129 days 4 177.0 mg/dl 5.5 11.0 oral glucose tolerance test 0.0 0 103809 2864
GK/MolTac maximum rate of positive change in left ventricular blood pressure to left ventricular end-diastolic volume ratio control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. heart left ventricular blood pressure trait male 112 days 8 104.0 mmHg/s/ul 10.0 28.28 vascular transducer tipped catheter 0.0 0 102988 2783
GK/MolTac heart left ventricle end-diastolic anterior wall index control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. heart left ventricle anterior wall thickness male 112 days 8 7.31 mm/kg 0.22 0.62 echocardiography 0.0 0 102994 2783
GK/MolTac heart left ventricle end-diastolic diameter to body weight ratio control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. heart left ventricle diameter male 112 days 8 15.29 mm/kg 0.51 1.44 echocardiography 0.0 0 102996 2783
GK/MolTac body weight control condition Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. body mass male 147 days 6 382.0 g 13.0 31.84 body weighing method 0.0 0 103981 2885
GK/MolTac blood insulin level control condition Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. blood insulin amount male 147 days 6 57.65 mU/l 11.47 28.1 blood insulin analysis 0.0 0 103999 2885
GK/MolTac blood dipeptidyl peptidase 4 activity level control condition Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. blood enzyme amount male 147 days 0 235.0 pmol/min 25.0 blood enzyme activity assay 0.0 0 104007 2885
GK/MolTac blood glucose level sodium chloride solution (for 23 days) then control condition (for 20 days) then fasting (for 16 hours) then glucose solution (2 g/kg) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood glucose amount male 122 days-129 days 4 162.0 mg/dl 14.0 28.0 oral glucose tolerance test 0.0 0 103808 2864
GK/MolTac plasma insulin level sodium chloride solution (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood insulin amount male 122 days-129 days 4 37.96 mU/l 6.5 13.0 oral glucose tolerance test 0.0 0 103815 2864
GK/MolTac serum aldosterone level control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. blood aldosterone amount male 112 days 8 3.63 nmol/l 0.91 2.59 radioimmunoassay 0.0 0 102945 2783
GK/MolTac food intake rate control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. eating behavior trait female 60 days 6 16.1 g/d 0.4 0.98 food intake measuring method 0.0 0 food consumption 106899 3071
GK/MolTac food intake rate control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. eating behavior trait female 240 days 11 15.7 g/d 0.3 0.99 food intake measuring method 0.0 0 food consumption 106900 3071
GK/MolTac food intake rate control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. eating behavior trait female 420 days 11 17.2 g/d 0.4 1.33 food intake measuring method 0.0 0 food consumption 106901 3071
GK/MolTac blood glucose level control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. blood glucose amount female 60 days 6 268.2 mg/dl 14.4 35.27 blood glucose test strip read by optical glucometer 0.0 0 tail vein blood fasting blood glucose, non fasting blood glucose 106905 3071
GK/MolTac both kidneys wet weight to body weight ratio control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. kidney mass female 420 days 0 3.14 g/kg 0.07 post excision weight measurement 0.0 0 kidney weight, kidney weight to body weight ratio 106953 3071
GK/MolTac serum fructosamine level control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. blood fructosamine amount female 0 days 11 253.0 umol/l 5.0 16.58 serum fructosamine analysis 0.0 0 serum fructosamine analysis 106955 3071
GK/MolTac serum insulin level control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. blood insulin amount female 240 days 11 0.0 mg/dl 0.0 0.0 enzyme linked immunosorbent assay 0.0 0 fasting insulin, non fasting insulin 106918 3071
GK/MolTac serum insulin level control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. blood insulin amount female 420 days 11 0.0 mg/dl 0.0 0.0 enzyme linked immunosorbent assay 0.0 0 fasting insulin, non fasting insulin 106919 3071
GK/MolTac kidney glomerulus basement membrane thickness control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. kidney glomerulus morphology trait female 420 days 0 337.0 nm 16.0 ex vivo electron microscopy with digital image analysis 0.0 0 kidney basement membrane thickness 106947 3071
GK/MolTac mean arterial blood pressure control condition Kold-Petersen H, etal., J Vasc Res. 2012;49(3):267-78. doi: 10.1159/000335487. Epub 2012 Apr 11. arterial blood pressure trait male 112 days 0 118.0 mmHg 1.0 tail cuff plethysmography 0.0 0 108031 3109
GK/MolTac blood glucose level control condition Kold-Petersen H, etal., J Vasc Res. 2012;49(3):267-78. doi: 10.1159/000335487. Epub 2012 Apr 11. blood glucose amount male 154 days 0 165.6 mg/dl 34.2 blood glucose test strip read by electrochemical glucometer 0.0 0 108037 3109
GK/MolTac blood glucose level control condition Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. blood glucose amount female 56 days 10 127.8 mg/dl 1.8 5.69 blood glucose analysis 0.0 0 110264 3168
GK/MolTac body weight control condition Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. body mass male 119 days 9 350.8 g 9.8 29.4 body weighing method 0.0 0 110737 3183
GK/MolTac arterial elastance control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. heart left ventricular blood pressure trait male 112 days 8 1.26 null 0.12 0.34 vascular transducer tipped catheter 0.0 0 102973 2783
GK/MolTac heart rate control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. heart pumping trait male 112 days 8 476.0 beats/min 18.0 50.91 vascular transducer tipped catheter 0.0 0 102955 2783
GK/MolTac systolic blood pressure control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. arterial blood pressure trait male 112 days 8 127.0 mmHg 5.0 14.14 vascular transducer tipped catheter 0.0 0 102957 2783
GK/MolTac red blood cell count rosiglitazone (5 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. erythrocyte quantity male 122 days-129 days 5 9.0 x 10E6 cells/ul 0.22 0.5 automated blood cell counting method 0.0 0 103846 2864
GK/MolTac red blood cell count rosiglitazone (10 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. erythrocyte quantity male 122 days-129 days 7 9.4 x 10E6 cells/ul 0.08 0.2 automated blood cell counting method 0.0 0 103847 2864
GK/MolTac blood hemoglobin level control condition (between 70 and 77 days) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood hemoglobin amount male 70 days-77 days 6 13.1 g/dl 1.18 2.9 automated hematology analysis 0.0 0 103852 2864
GK/MolTac blood hemoglobin level sodium chloride solution (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood hemoglobin amount male 122 days-129 days 7 16.2 g/dl 0.45 1.2 automated hematology analysis 0.0 0 103857 2864
GK/MolTac hematocrit control condition (between 70 and 77 days) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. erythrocyte quantity male 70 days-77 days 6 42.3 % 3.8 9.3 automated hematology analysis 0.0 0 103864 2864
GK/MolTac hematocrit control condition (between 70 and 77 days) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. erythrocyte quantity male 70 days-77 days 7 46.0 % 2.0 5.3 automated hematology analysis 0.0 0 103865 2864
GK/MolTac whole body insulin sensitivity index rosiglitazone (5 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood insulin amount male 122 days-129 days 4 10,000/√(FG x FI) x (Ḡ x Ī) 1.27 null 0.23 0.46 oral glucose tolerance test 7200.0 0 measured at -5,15,30,45,60,90,120 min 103830 2864
GK/MolTac red blood cell count control condition (between 70 and 77 days) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. erythrocyte quantity male 70 days-77 days 6 6.6 x 10E6 cells/ul 0.57 1.4 automated blood cell counting method 0.0 0 103840 2864
GK/MolTac blood glucose level control condition Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. blood glucose amount male 144 days 12 352.0 mg/dl 39.0 135.1 blood glucose analysis 0.0 0 103992 2885
GK/MolTac preload recruitable left ventricle stroke work control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. cardiac output trait male 112 days 8 73.0 mmHg 6.0 16.97 vascular transducer tipped catheter 0.0 0 102983 2783
GK/MolTac blood malondialdehyde level control condition then controlled saxagliptin content diet (10 mg/kg/d) (for 12 days) Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. blood malondialdehyde amount male 147 days 0 6.5 umol/l 1.0 thiobarbituric acid assay 0.0 0 104019 2885
GK/MolTac plasma insulin level rosiglitazone (10 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood insulin amount male 122 days-129 days 4 27.3 mU/l 4.16 8.32 oral glucose tolerance test 0.0 0 103817 2864
GK/MolTac plasma triglyceride level control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. blood triglyceride amount male 112 days 8 0.68 mmol/l 0.12 0.35 automated plasma triglyceride analysis 0.0 0 102941 2783
GK/MolTac blood glucose level control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. blood glucose amount female 240 days 11 311.4 mg/dl 14.4 47.76 blood glucose test strip read by optical glucometer 0.0 0 fasting blood glucose, non fasting blood glucose 106906 3071
GK/MolTac systolic blood pressure control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. arterial blood pressure trait female 60 days 6 114.0 mmHg 0.09 0.22 tail cuff plethysmography 0.0 0 10 consecutive measurements 106929 3071
GK/MolTac systolic blood pressure control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. arterial blood pressure trait female 240 days 11 124.0 mmHg 3.0 9.95 tail cuff plethysmography 0.0 0 10 consecutive measurements 106930 3071
GK/MolTac systolic blood pressure control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. arterial blood pressure trait female 420 days 11 116.0 mmHg 1.7 5.64 tail cuff plethysmography 0.0 0 10 consecutive measurements 106931 3071
GK/MolTac body weight control condition Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. body mass male 105 days 9 337.3 g 7.8 23.4 body weighing method 0.0 0 110731 3183
GK/MolTac blood glucose level control condition Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. blood glucose amount female 56 days 9 120.6 mg/dl 1.8 5.4 blood glucose analysis 0.0 0 110263 3168
GK/MolTac body weight control condition Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. body mass female 56 days 10 191.0 g 3.0 9.49 body weighing method 0.0 0 110244 3168
GK/MolTac hematocrit control condition (between 70 and 77 days) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. erythrocyte quantity male 70 days-77 days 7 50.0 % 1.06 2.8 automated hematology analysis 0.0 0 103863 2864
GK/MolTac hematocrit sodium chloride solution (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. erythrocyte quantity male 122 days-129 days 7 53.4 % 1.44 3.8 automated hematology analysis 0.0 0 103869 2864
GK/MolTac blood hemoglobin A1c level control condition (between 70 and 77 days) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood hemoglobin amount male 70 days-77 days 6 4.75 % 0.06 0.14 automated hematology analysis 0.0 0 103876 2864
GK/MolTac blood hemoglobin A1c level rosiglitazone (5 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood hemoglobin amount male 122 days-129 days 5 5.2 % 0.1 0.22 automated hematology analysis 0.0 0 103882 2864
GK/MolTac blood insulin level AUC to blood glucose level AUC ratio sodium chloride solution (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood insulin amount male 122 days-129 days 4 AUC ins/glu 0.0 null 0.0 0.0 oral glucose tolerance test 7200.0 0 measured at -5,15,30,45,60,90,120 min 103822 2864
GK/MolTac whole body insulin sensitivity index sodium chloride solution (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood insulin amount male 122 days-129 days 4 10,000/√(FG x FI) x (Ḡ x Ī) 1.49 null 0.31 0.62 oral glucose tolerance test 7200.0 0 measured at -5,15,30,45,60,90,120 min 103829 2864
GK/MolTac Homeostatic Model Assessment of Insulin Resistance sodium chloride solution (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood insulin amount male 122 days-129 days 4 (fasting glucose x fasting insulin)/22.5 13.0 null 2.65 5.3 oral glucose tolerance test 7200.0 0 103836 2864
GK/MolTac maximum rate of positive change in left ventricular blood pressure control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. heart left ventricular blood pressure trait male 112 days 8 10429.0 mmHg/s 568.0 1606.55 vascular transducer tipped catheter 0.0 0 102977 2783
GK/MolTac blood dipeptidyl peptidase 4 activity level control condition Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. blood enzyme amount male 147 days 0 235.0 pmol/min 25.0 blood enzyme activity assay 0.0 0 104009 2885
GK/MolTac urine glucose level control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. urine glucose amount male 112 days 8 86.0 mg/dl 31.0 87.68 urine analysis 0.0 0 102951 2783
GK/MolTac blood hemoglobin level rosiglitazone (5 mg/kg) (for 23 days) then control condition (for 60 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood hemoglobin amount male 164 days-171 days 5 16.7 g/dl 0.72 1.6 automated hematology analysis 0.0 0 103861 2864
GK/MolTac hematocrit rosiglitazone (10 mg/kg) (for 23 days) then control condition (for 60 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. erythrocyte quantity male 164 days-171 days 7 57.7 % 0.23 0.6 automated hematology analysis 0.0 0 103874 2864
GK/MolTac blood hemoglobin A1c level rosiglitazone (10 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood hemoglobin amount male 122 days-129 days 7 5.19 % 0.08 0.2 automated hematology analysis 0.0 0 103883 2864
GK/MolTac blood insulin level AUC to blood glucose level AUC ratio rosiglitazone (5 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood insulin amount male 122 days-129 days 4 AUC ins/glu 0.0 null 0.0 0.0 oral glucose tolerance test 7200.0 0 measured at -5,15,30,45,60,90,120 min 103823 2864
GK/MolTac blood insulin level AUC to blood glucose level AUC ratio rosiglitazone (10 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood insulin amount male 122 days-129 days 4 AUC ins/glu 0.0 null 0.0 0.0 oral glucose tolerance test 7200.0 0 measured at -5,15,30,45,60,90,120 min 103824 2864
GK/MolTac Homeostatic Model Assessment of Insulin Resistance rosiglitazone (10 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood insulin amount male 122 days-129 days 4 (fasting glucose x fasting insulin)/22.5 8.2 null 1.35 2.7 oral glucose tolerance test 7200.0 0 103838 2864
GK/MolTac left ventricular diastolic blood pressure control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. heart left ventricular blood pressure trait male 112 days 8 5.7 mmHg 0.4 1.13 vascular transducer tipped catheter 0.0 0 102985 2783
GK/MolTac body weight control condition Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. body mass male 147 days 0 389.0 g 7.0 body weighing method 0.0 0 103983 2885
GK/MolTac body weight control condition then controlled saxagliptin content diet (10 mg/kg/d) (for 12 days) Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. body mass male 147 days 0 389.0 g 7.0 body weighing method 0.0 0 103985 2885
GK/MolTac blood glucose level control condition then controlled saxagliptin content diet (10 mg/kg/d) (for 12 days) Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. blood glucose amount male 144 days 12 305.0 mg/dl 18.0 62.35 blood glucose analysis 0.0 0 103994 2885
GK/MolTac blood malondialdehyde level control condition Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. blood malondialdehyde amount male 147 days 0 6.7 umol/l 1.7 thiobarbituric acid assay 0.0 0 104015 2885
GK/MolTac plasma NH2-terminal pro-B-type natriuretic peptide level control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. blood protein amount male 112 days 8 3416.0 ng/l 585.0 1654.63 electrochemiluminescence immunoassay 0.0 0 plasma pro bnp 102933 2783
GK/MolTac plasma total cholesterol level control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. blood cholesterol amount male 112 days 8 96.0 mg/dl 7.0 19.8 automated plasma total cholesterol analysis 0.0 0 102939 2783
GK/MolTac blood glucose level control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. blood glucose amount female 420 days 11 289.8 mg/dl 10.8 35.82 blood glucose test strip read by optical glucometer 0.0 0 fasting blood glucose, non fasting blood glucose 106907 3071
GK/MolTac liver wet weight control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. liver mass female 420 days 0 9.91 g 0.38 post excision weight measurement 0.0 0 106943 3071
GK/MolTac heart wet weight control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. heart mass female 420 days 0 0.86 g 0.02 post excision weight measurement 0.0 0 106945 3071
GK/MolTac body weight control condition Kold-Petersen H, etal., J Vasc Res. 2012;49(3):267-78. doi: 10.1159/000335487. Epub 2012 Apr 11. body mass male 112 days 0 351.0 g 5.0 body weighing method 0.0 0 108025 3109
GK/MolTac mean arterial blood pressure control condition Kold-Petersen H, etal., J Vasc Res. 2012;49(3):267-78. doi: 10.1159/000335487. Epub 2012 Apr 11. arterial blood pressure trait male 154 days 0 127.0 mmHg 4.0 tail cuff plethysmography 0.0 0 108033 3109
GK/MolTac blood glucose level control condition Kold-Petersen H, etal., J Vasc Res. 2012;49(3):267-78. doi: 10.1159/000335487. Epub 2012 Apr 11. blood glucose amount male 112 days 0 190.8 mg/dl 7.2 blood glucose test strip read by electrochemical glucometer 0.0 0 108035 3109
GK/MolTac body weight control condition Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. body mass male 105 days 10 335.6 g 5.2 16.44 body weighing method 0.0 0 110730 3183
GK/MolTac body weight control condition Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. body mass male 112 days 8 337.1 g 9.3 26.3 body weighing method 0.0 0 110732 3183
GK/MolTac body weight control condition Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. body mass male 119 days 8 343.0 g 9.0 25.46 body weighing method 0.0 0 110735 3183
GK/MolTac body weight control condition Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. body mass male 119 days 10 350.1 g 7.7 24.35 body weighing method 0.0 0 110736 3183
GK/MolTac serum 8-epi-prostaglandin F2alpha level control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. blood eicosanoid amount female 0 days 11 973.0 ng/l 243.0 805.94 enzyme immunoassay 0.0 0 blood 8-epi-prostaglandin F2alpha amount 108087 3071
GK/MolTac body weight control condition Schrijvers BF, et al., Horm Metab Res. 2005 Jan;37(1):21-5. doi: 10.1055/s-2005-861027. body mass female 56 days 9 188.0 g 3.0 9.0 body weighing method 0.0 0 110243 3168
GK/MolTac middle cerebral artery outer diameter control condition Kold-Petersen H, etal., J Vasc Res. 2012;49(3):267-78. doi: 10.1159/000335487. Epub 2012 Apr 11. cerebral artery size trait male 154 days 20 215.0 um 10.0 44.72 ex vivo light microscopy with inverted microscope 0.0 0 with video image analysis 109092 3109
GK/MolTac red blood cell count rosiglitazone (5 mg/kg) (for 23 days) then control condition (for 60 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. erythrocyte quantity male 164 days-171 days 5 9.3 x 10E6 cells/ul 0.36 0.8 automated blood cell counting method 0.0 0 103849 2864
GK/MolTac plasma renin activity level control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. renin activity male 112 days 8 4.8 ng/ml/h 1.9 5.37 radioimmunoassay 0.0 0 102947 2783
GK/MolTac urine norepinephrine level control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. urine norepinephrine amount male 112 days 8 2743.0 nmol/l 883.0 2497.5 urine analysis 0.0 0 102953 2783
GK/MolTac red blood cell count sodium chloride solution (for 23 days) then control condition (for 60 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. erythrocyte quantity male 164 days-171 days 7 9.8 x 10E6 cells/ul 0.3 0.8 automated blood cell counting method 0.0 0 103848 2864
GK/MolTac blood hemoglobin level control condition (between 70 and 77 days) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood hemoglobin amount male 70 days-77 days 7 14.4 g/dl 0.6 1.6 automated hematology analysis 0.0 0 103853 2864
GK/MolTac blood hemoglobin level rosiglitazone (5 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood hemoglobin amount male 122 days-129 days 5 16.3 g/dl 0.54 1.2 automated hematology analysis 0.0 0 103858 2864
GK/MolTac blood hemoglobin level rosiglitazone (10 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood hemoglobin amount male 122 days-129 days 7 17.0 g/dl 0.19 0.5 automated hematology analysis 0.0 0 103859 2864
GK/MolTac blood hemoglobin level rosiglitazone (10 mg/kg) (for 23 days) then control condition (for 60 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood hemoglobin amount male 164 days-171 days 7 17.8 g/dl 0.08 0.2 automated hematology analysis 0.0 0 103862 2864
GK/MolTac blood hemoglobin A1c level control condition (between 70 and 77 days) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood hemoglobin amount male 70 days-77 days 7 4.8 % 0.07 0.19 automated hematology analysis 0.0 0 103877 2864
GK/MolTac blood hemoglobin A1c level rosiglitazone (5 mg/kg) (for 23 days) then control condition (for 60 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood hemoglobin amount male 164 days-171 days 7 5.86 % 0.24 0.64 automated hematology analysis 0.0 0 103885 2864
GK/MolTac blood hemoglobin A1c level rosiglitazone (10 mg/kg) (for 23 days) then control condition (for 60 days) then fasting (for 12 hours) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood hemoglobin amount male 164 days-171 days 7 5.61 % 0.12 0.32 automated hematology analysis 0.0 0 103886 2864
GK/MolTac blood glucose level rosiglitazone (10 mg/kg) (for 23 days) then control condition (for 20 days) then fasting (for 16 hours) then glucose solution (2 g/kg) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. blood glucose amount male 122 days-129 days 4 145.0 mg/dl 7.5 15.0 oral glucose tolerance test 0.0 0 103810 2864
GK/MolTac red blood cell count control condition (between 70 and 77 days) Gao W and Jusko WJ, J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29. erythrocyte quantity male 70 days-77 days 7 7.8 x 10E6 cells/ul 0.15 0.4 automated blood cell counting method 0.0 0 103839 2864
GK/MolTac blood insulin level control condition Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. blood insulin amount male 147 days 12 65.29 mU/l 8.82 30.57 blood insulin analysis 0.0 0 104001 2885
GK/MolTac blood malondialdehyde level control condition Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. blood malondialdehyde amount male 147 days 0 6.7 umol/l 1.6 thiobarbituric acid assay 0.0 0 104017 2885
GK/MolTac plasma troponin T level control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. blood protein amount male 112 days 8 3044.0 pg/ml 750.0 2121.32 electrochemiluminescence immunoassay 0.0 0 102935 2783
GK/MolTac plasma glucose level control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. blood glucose amount male 112 days 8 223.2 mg/dl 32.4 91.64 automated plasma glucose analysis 0.0 0 102937 2783
GK/MolTac body weight control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. body mass female 240 days 11 280.0 g 6.0 19.9 body weighing method 0.0 0 body weight 106894 3071
GK/MolTac kidney fractional mesangial volume control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. kidney glomerulus morphology trait female 420 days 0 35.0 % 1.7 ex vivo electron microscopy with digital image analysis 0.0 0 kidney fractional mesangial volume 106949 3071
GK/MolTac both kidneys wet weight control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. kidney mass female 420 days 0 0.92 g 0.02 post excision weight measurement 0.0 0 kidney weight, kidney weight to body weight ratio 106939 3071
GK/MolTac body weight control condition Kold-Petersen H, etal., J Vasc Res. 2012;49(3):267-78. doi: 10.1159/000335487. Epub 2012 Apr 11. body mass male 154 days 0 419.0 g 7.0 body weighing method 0.0 0 108027 3109
GK/MolTac heart weight control condition Kold-Petersen H, etal., J Vasc Res. 2012;49(3):267-78. doi: 10.1159/000335487. Epub 2012 Apr 11. heart mass male 154 days 0 1.39 g 0.06 post excision weight measurement 0.0 0 108029 3109
GK/MolTac body weight control condition Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. body mass male 112 days 10 352.4 g 6.5 20.55 body weighing method 0.0 0 110733 3183
GK/MolTac body weight control condition Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. body mass male 112 days 9 345.8 g 8.4 25.2 body weighing method 0.0 0 110734 3183
GK/MolTac tissue mitochondrial DNA to nuclear DNA ratio control condition Keller AC, et al., J Cardiovasc Pharmacol. 2015 Feb;65(2):137-47. doi: 10.1097/FJC.0000000000000170. tissue DNA amount male 147 days 6 913.5 null 400.9 982.0 real-time polymerase chain reaction assay 0.0 0 tissue mitochondrial DNA to nuclear DNA ratio (CMO:0003889) 138274 2885
GK/MolTac heart left ventricle end-diastolic posterior wall index control condition Korkmaz-Ic?z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. heart left ventricle posterior wall thickness male 112 days 8 8.85 mm/kg 0.31 0.88 echocardiography 0.0 0 102992 2783