Phenominer Database Results (32 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Experiment Notes Record ID Study ID
SS-Chr 15BN/Mcwi urine albumin excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine albumin amount male 80 days-99 days 7 57.74 mg/d 11.69 30.93 radioimmunoassay 0 Moms were fed Teklad, pups used in studies were fed Dyets 52598 482
SS-Chr 15BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80 days-99 days 7 1.97 mEq/d 0.89 2.35 flame atomic emission spectrometry 0 urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52945 482
SS-Chr 15BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80 days-99 days 3 1.78 ml/min 0.21 0.37 urine creatinine analysis 0 Moms were fed Teklad, pups used in studies were fed Dyets 52160 482
SS-Chr 15BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80 days-99 days 3 1.73 ng/ml/h 0.2 0.35 radioimmunoassay 0 Moms were fed Teklad, pups used in studies were fed Dyets 52454 482
SS-Chr 15BN/Mcwi body weight controlled sodium content diet (4 %) (for 21 days) PhysGen Vascular data body mass female 70 days-84 days 10 215.0 g 4.2 13.3 whole body digital scale 0 Moms and pups used in studies were fed Teklad 55199 522
SS-Chr 15BN/Mcwi logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait female 70 days-84 days 10 -8.42 null 0.23 0.71 wire myography using a Digi-Med tissue force analysis system with force transducer 0 EC50 value is moles/liter Moms and pups used in studies were fed Teklad 56124 522
SS-Chr 15BN/Mcwi logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70 days-84 days 10 -6.94 null 0.06 0.18 wire myography using a Digi-Med tissue force analysis system with force transducer 0 Moms and pups used in studies were fed Teklad 56934 522
SS-Chr 15BN/Mcwi urine total protein excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data total urine protein amount male 80 days-99 days 7 139.22 mg/d 35.75 94.58 automated urine total protein analysis 0 Moms were fed Teklad, pups used in studies were fed Dyets 52698 482
SS-Chr 15BN/Mcwi maximum contractile force per wet weight of aorta controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours) PhysGen Vascular data vasoconstriction trait female 70 days-84 days 10 1.19 g/mg 0.11 0.35 wire myography using a Digi-Med tissue force analysis system with force transducer 0 Moms and pups used in studies were fed Teklad 57353 522
SS-Chr 15BN/Mcwi plasma creatinine level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data blood creatinine amount female 80 days-99 days 3 0.38 mg/dl 0.04 0.07 radioimmunoassay 0 Moms were fed Teklad, pups used in studies were fed Dyets 52209 482
SS-Chr 15BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80 days-99 days 7 364.71 beats/min 8.9 23.56 vascular fluid filled catheter 0 Moms were fed Teklad, pups used in studies were fed Dyets 52649 482
SS-Chr 15BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80 days-99 days 7 2.52 ml/min 0.27 0.71 urine creatinine analysis 0 Moms were fed Teklad, pups used in studies were fed Dyets 52159 482
SS-Chr 15BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80 days-99 days 5 154.32 mmHg 18.48 41.32 vascular fluid filled catheter 0 Moms were fed Teklad, pups used in studies were fed Dyets 52848 482
SS-Chr 15BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80 days-99 days 5 403.16 beats/min 14.0 31.31 vascular fluid filled catheter 0 Moms were fed Teklad, pups used in studies were fed Dyets 52650 482
SS-Chr 15BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80 days-99 days 7 0.28 ng/ml/h 0.02 0.05 radioimmunoassay 0 Moms were fed Teklad, pups used in studies were fed Dyets 52453 482
SS-Chr 15BN/Mcwi concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70 days-84 days 8 2.23 E-7mole 0.45 1.27 wire myography using a Digi-Med tissue force analysis system with force transducer 0 Moms and pups used in studies were fed Teklad 56537 522
SS-Chr 15BN/Mcwi urine albumin excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine albumin amount female 80 days-99 days 7 46.16 mg/d 15.16 40.11 radioimmunoassay 0 Moms were fed Teklad, pups used in studies were fed Dyets 52599 482
SS-Chr 15BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80 days-99 days 7 20.45 mEq/d 2.19 5.79 flame atomic emission spectrometry 0 Moms were fed Teklad, pups used in studies were fed Dyets 52749 482
SS-Chr 15BN/Mcwi body weight controlled sodium content diet (4 %) (for 21 days) PhysGen Vascular data body mass male 70 days-84 days 10 307.1 g 6.9 21.9 whole body digital scale 0 Moms and pups used in studies were fed Teklad 55197 522
SS-Chr 15BN/Mcwi concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait female 70 days-84 days 10 0.01 umol/l 0.0 0.01 wire myography using a Digi-Med tissue force analysis system with force transducer 0 Moms and pups used in studies were fed Teklad 54925 522
SS-Chr 15BN/Mcwi concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70 days-84 days 10 1.23 E-7mole 0.16 0.49 wire myography using a Digi-Med tissue force analysis system with force transducer 0 Moms and pups used in studies were fed Teklad 56539 522
SS-Chr 15BN/Mcwi logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70 days-84 days 8 -6.72 null 0.1 0.28 wire myography using a Digi-Med tissue force analysis system with force transducer 0 Moms and pups used in studies were fed Teklad 56932 522
SS-Chr 15BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80 days-99 days 7 159.66 mmHg 5.64 14.91 vascular fluid filled catheter 0 Moms were fed Teklad, pups used in studies were fed Dyets 52847 482
SS-Chr 15BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80 days-99 days 7 0.99 mEq/d 0.14 0.36 flame atomic emission spectrometry 0 urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52946 482
SS-Chr 15BN/Mcwi maximum contractile force per wet weight of aorta controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours) PhysGen Vascular data vasoconstriction trait male 70 days-84 days 10 0.57 g/mg 0.06 0.17 wire myography using a Digi-Med tissue force analysis system with force transducer 0 Moms and pups used in studies were fed Teklad 57351 522
SS-Chr 15BN/Mcwi urine total protein excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data total urine protein amount female 80 days-99 days 7 95.15 mg/d 25.23 66.74 automated urine total protein analysis 0 Moms were fed Teklad, pups used in studies were fed Dyets 52699 482
SS-Chr 15BN/Mcwi logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait male 70 days-84 days 9 -7.82 null 0.14 0.42 wire myography using a Digi-Med tissue force analysis system with force transducer 0 EC50 value is moles/liter Moms and pups used in studies were fed Teklad 56122 522
SS-Chr 15BN/Mcwi acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70 days-84 days 8 73.63 % 6.48 18.32 wire myography using a Digi-Med tissue force analysis system with force transducer 0 Moms and pups used in studies were fed Teklad 54797 522
SS-Chr 15BN/Mcwi acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70 days-84 days 10 64.6 % 7.03 22.22 wire myography using a Digi-Med tissue force analysis system with force transducer 0 Moms and pups used in studies were fed Teklad 54799 522
SS-Chr 15BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80 days-99 days 7 14.44 mEq/d 3.52 9.31 flame atomic emission spectrometry 0 Moms were fed Teklad, pups used in studies were fed Dyets 52750 482
SS-Chr 15BN/Mcwi plasma creatinine level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data blood creatinine amount male 80 days-99 days 7 0.36 mg/dl 0.02 0.06 radioimmunoassay 0 Moms were fed Teklad, pups used in studies were fed Dyets 52208 482
SS-Chr 15BN/Mcwi concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait male 70 days-84 days 9 0.02 umol/l 0.01 0.02 wire myography using a Digi-Med tissue force analysis system with force transducer 0 Moms and pups used in studies were fed Teklad 54923 522