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# of AnimalsPhenotypeStrainSexValueUnitsConditionsRecord IDCondition 1aCondition 1bCondition 2aCondition 2bCondition 3aCondition 3b
7urine sodium excretion rateFHH-Chr 8BN/Mcwifemale18.5163mEq/dcontrolled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)52782controlled sodium content diet (8 %) (between 19 and 22 days)controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)
4urine sodium excretion rateFHH-Chr 8BN/Mcwimale21.1452mEq/dcontrolled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)52793controlled sodium content diet (8 %) (between 19 and 22 days)controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)
2plasma renin activity levelFHH-Chr 8BN/Mcwifemale3.48ng/ml/hcontrolled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)52880controlled sodium content diet (8 %) (between 19 and 22 days)controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)
2plasma renin activity levelFHH-Chr 8BN/Mcwimale2.105ng/ml/hcontrolled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)52891controlled sodium content diet (8 %) (between 19 and 22 days)controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)
7urine total protein excretion rateFHH-Chr 8BN/Mcwifemale65.0143mg/dcontrolled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)52096controlled sodium content diet (8 %) (between 19 and 22 days)controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)
4urine total protein excretion rateFHH-Chr 8BN/Mcwimale401.0062mg/dcontrolled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)52107controlled sodium content diet (8 %) (between 19 and 22 days)controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)
7plasma creatinine levelFHH-Chr 8BN/Mcwifemale0.3271mg/dlcontrolled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)52245controlled sodium content diet (8 %) (between 19 and 22 days)controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)
3plasma creatinine levelFHH-Chr 8BN/Mcwimale0.31mg/dlcontrolled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)52256controlled sodium content diet (8 %) (between 19 and 22 days)controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)
7urine potassium excretion rateFHH-Chr 8BN/Mcwifemale1.1866mEq/dcontrolled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)52294controlled sodium content diet (8 %) (between 19 and 22 days)controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)
4urine potassium excretion rateFHH-Chr 8BN/Mcwimale1.174mEq/dcontrolled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)52305controlled sodium content diet (8 %) (between 19 and 22 days)controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)
6creatinine clearanceFHH-Chr 8BN/Mcwifemale1.3478ml/mincontrolled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)52341controlled sodium content diet (8 %) (between 19 and 22 days)controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)
3creatinine clearanceFHH-Chr 8BN/Mcwimale1.881ml/mincontrolled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)52352controlled sodium content diet (8 %) (between 19 and 22 days)controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)
7urine albumin excretion rateFHH-Chr 8BN/Mcwifemale29.5891mg/dcontrolled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)52388controlled sodium content diet (8 %) (between 19 and 22 days)controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)
4urine albumin excretion rateFHH-Chr 8BN/Mcwimale144.625mg/dcontrolled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)52399controlled sodium content diet (8 %) (between 19 and 22 days)controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)
8heart rateFHH-Chr 8BN/Mcwifemale429.9016beats/mincontrolled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)52486controlled sodium content diet (8 %) (between 19 and 22 days)controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)
3heart rateFHH-Chr 8BN/Mcwimale404.674beats/mincontrolled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)52497controlled sodium content diet (8 %) (between 19 and 22 days)controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)
8mean arterial blood pressureFHH-Chr 8BN/Mcwifemale141.229mmHgcontrolled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)52533controlled sodium content diet (8 %) (between 19 and 22 days)controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)
3mean arterial blood pressureFHH-Chr 8BN/Mcwimale159.6053mmHgcontrolled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)52544controlled sodium content diet (8 %) (between 19 and 22 days)controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)
10concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH-Chr 8BN/Mcwifemale2.4364E-7molecontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)56531controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
9concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH-Chr 8BN/Mcwimale5.3688E-7molecontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)56543controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
10maximum contractile force per wet weight of aortaFHH-Chr 8BN/Mcwifemale1.058g/mgcontrolled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)57345controlled sodium content diet (4 %) (for 21 days)potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
10maximum contractile force per wet weight of aortaFHH-Chr 8BN/Mcwimale0.947g/mgcontrolled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)57357controlled sodium content diet (4 %) (for 21 days)potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
10acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselFHH-Chr 8BN/Mcwifemale78.8%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)54791controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
9acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselFHH-Chr 8BN/Mcwimale61.7778%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)54803controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
10logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH-Chr 8BN/Mcwifemale-6.8058controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)56926controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
9logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH-Chr 8BN/Mcwimale-6.6664controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)56938controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
9concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)FHH-Chr 8BN/Mcwifemale0.0193umol/lcontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)54917controlled sodium content diet (4 %) (for 21 days)phenylephrine (0-300 umol/l) drug dose time series (for 1.2 hours)
10concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)FHH-Chr 8BN/Mcwimale0.0119umol/lcontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)54929controlled sodium content diet (4 %) (for 21 days)phenylephrine (0-300 umol/l) drug dose time series (for 1.2 hours)
9logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)FHH-Chr 8BN/Mcwifemale-7.8689controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)56116controlled sodium content diet (4 %) (for 21 days)phenylephrine (0-300 umol/l) drug dose time series (for 1.2 hours)
10logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)FHH-Chr 8BN/Mcwimale-8.0684controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)56128controlled sodium content diet (4 %) (for 21 days)phenylephrine (0-300 umol/l) drug dose time series (for 1.2 hours)
10body weightFHH-Chr 8BN/Mcwifemale179gcontrolled sodium content diet (4 %) (for 21 days)55192controlled sodium content diet (4 %) (for 21 days)
10body weightFHH-Chr 8BN/Mcwimale267.6gcontrolled sodium content diet (4 %) (for 21 days)55203controlled sodium content diet (4 %) (for 21 days)