Phenominer

Phenominer Database Results (10000 results)

How to display a graph

Strain	Phenotype	Conditions	Study	Experiment Name	Sex	Age	# of Animals	Formula	Average Type	Value	Units	SEM	SD	Method	Method Site	Method Duration	Post Insult Type	Post Insult Time Value	Post Insult Time Unit	Method Notes	Clinical Measurement Notes	Experiment Notes	Record ID	Study ID
SS/Jr	systolic blood pressure	controlled sodium content diet (2 %) (between 24 and 28 days)	Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.	arterial blood pressure trait	male	63 days-70 days	20			202.0	mmHg	4.1	18.34	tail cuff plethysmography		0		0			average of 4days		65483	611
SS.LEW-(D1Rat211-D1Rat18)/Mco	systolic blood pressure	controlled sodium content diet (2 %) (between 24 and 28 days)	Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.	arterial blood pressure trait	male	63 days-70 days	20			179.0	mmHg	2.9	12.97	tail cuff plethysmography		0		0			average of 4days		65490	611
SS.LEW-(D1Mco75-D1Rat18)/Mco	systolic blood pressure	controlled sodium content diet (2 %) (between 24 and 28 days)	Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.	arterial blood pressure trait	male	63 days-70 days	20			193.0	mmHg	4.2	18.78	tail cuff plethysmography		0		0			average of 4days		65492	611
SS.LEW-(D1Rat211-D1Rat18)/Mco	heart rate	controlled sodium content diet (2 %) (between 34 and 38 days)	Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.	heart pumping trait	male	73 days-80 days	8			404.0	beats/min	5.0	14.14	intra-aortic abdominal radiotelemetry		10		0			diurnal difference		65504	611
SS.LEW-(D1Rat211-D1Rat18)/Mco	pulse pressure	controlled sodium content diet (2 %) (between 34 and 38 days)	Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.	arterial blood pressure trait	male	73 days-80 days	8			49.0	mmHg	0.74	2.09	intra-aortic abdominal radiotelemetry		10		0			average of 24 hr		65500	611
SS/Jr	absolute change in systolic blood pressure	controlled sodium content diet (2 %) (between 34 and 38 days) then controlled exposure to darkness then controlled exposure to ambient light	Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.	arterial blood pressure trait	male	73 days-80 days	8			22.6	mmHg	1.05	2.97	intra-aortic abdominal radiotelemetry		10		0			diurnal difference		65497	611
SS-Mas1em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			317.5	beats/min	19.5	27.58	radiotelemetry	carotid artery			0				-	66623	717
SS-Gpr183em2Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	9	1/3 systolic pressure + 2/3 diastolic pressure		148.56	mmHg	5.69	17.06	radiotelemetry	carotid artery			0				-	66641	717
SS-Gpr183em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	3	1/3 systolic pressure + 2/3 diastolic pressure		140.33	mmHg	10.48	18.15	radiotelemetry	carotid artery			0				-	66653	717
SS-Ets1em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	3	1/3 systolic pressure + 2/3 diastolic pressure		139.33	mmHg	15.68	27.15	radiotelemetry	carotid artery			0				-	66655	717
SS-Rag1em2Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	7	1/3 systolic pressure + 2/3 diastolic pressure		123.14	mmHg	6.08	16.08	radiotelemetry	carotid artery			0				-	66661	717
SS-Renem1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	1/3 systolic pressure + 2/3 diastolic pressure		155.25	mmHg	12.05	24.1	radiotelemetry	carotid artery			0				-	66671	717
SS-Chr 5BN-Cyp4a2em1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	6	1/3 systolic pressure + 2/3 diastolic pressure		124.67	mmHg	2.17	5.32	radiotelemetry	carotid artery			0				-	66681	717
SS-Gpr183em3Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	7	1/3 systolic pressure + 2/3 diastolic pressure		145.0	mmHg	9.6	25.4	radiotelemetry	carotid artery			0				-	66682	717
SS-Acad10em2Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	5	1/3 systolic pressure + 2/3 diastolic pressure		137.0	mmHg	3.78	8.46	radiotelemetry	carotid artery			0				-	66686	717
SS-Alms1em1Mcwi-/-	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	6			7.77	mg/d	1.02	2.49	automated urine analysis				0				-	66692	717
SS-Mthfrem1Mcwi+/+	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	1			11.47	mg/d			automated urine analysis				0				-	66698	717
SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi+/+	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	2			9.78	mg/d	0.8	1.13	automated urine analysis				0				-	66710	717
SS-Apoeem7Mcwi-/-	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	5			11.01	mg/d	0.65	1.45	automated urine analysis				0				-	66718	717
SS-Nox4em2Mcwi+/+	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	3			12.06	mg/d	1.27	2.2	automated urine analysis				0				-	66721	717
SS-Nox4em2Mcwi-/-	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	5			10.89	mg/d	0.69	1.53	automated urine analysis				0				-	66730	717
SS-Chr 5BN-Cyp4a2em1Mcwi-/-	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	7			11.76	mg/d	0.57	1.51	automated urine analysis				0				-	66742	717
SS-Acad10em2Mcwi-/-	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	12			1.51	g	0.03	0.12	post excision weight measurement				0				-	66758	717
SS-Mthfrem1Mcwi+/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	1			1.63	g			post excision weight measurement				0				-	66759	717
SS-Nckap5em1Mcwi-/-	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	7			1.48	g	0.08	0.21	post excision weight measurement				0				-	66762	717
SS-Nckap5em2Mcwi-/-	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	8			1.71	g	0.05	0.14	post excision weight measurement				0				-	66767	717
SS-Nckap5em1Mcwi+/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	5			1.67	g	0.08	0.18	post excision weight measurement				0				-	66780	717
SS-Alms1em1Mcwi+/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	1			1.47	g			post excision weight measurement				0				-	66790	717
SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi-/-	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	4			1.41	g	0.05	0.1	post excision weight measurement				0				-	66793	717
SS-Tfdp2em2Mcwi-/-	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	3			1.37	g	0.01	0.02	post excision weight measurement				0				-	66798	717
SS-Cybaem1Mcwi+/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	2			1.52	g	0.11	0.15	post excision weight measurement				0				-	66799	717
SS-Itga9em1Mcwi+/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	4			1.48	g	0.01	0.01	post excision weight measurement				0				-	66801	717
SS-Ncf2em1Mcwi-/-	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	6			11.43	mEq/d	0.64	1.56	automated urine analysis				0				-	66812	717
SS-Ube2q2em3Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	1			11.19	mEq/d			automated urine analysis				0				-	66819	717
SS-Tgfb1em3Mcwi+/-	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	3			11.14	mEq/d	1.82	3.16	automated urine analysis				0				-	66823	717
SS.LEW-(D1Mco102-D1Mco129)/1Mco	systolic blood pressure	controlled sodium content diet (0.4 %) (between 36 and 40 days)	Joe B, et al., Hum Mol Genet. 2009 Aug 1;18(15):2825-38. Epub 2009 May 7.	arterial blood pressure trait	male	66 days-70 days	20		serial mean	172.0	mmHg	1.9	8.5	tail cuff plethysmography		345600		0		Rats warmed to 28 degrees C for measurement.			65310	565
SS/Jr	heart wet weight	controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)	Joe B, et al., Hum Mol Genet. 2009 Aug 1;18(15):2825-38. Epub 2009 May 7.	heart mass	male	64 days-70 days	20		serial mean	1.32	g	0.01	0.06	post excision weight measurement		345600		0					65314	565
SS/JrHsdMcwi	systolic blood pressure	controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	arterial blood pressure trait	female	92 days-94 days	12		serial mean	160.0	mmHg	6.0	20.78	vascular indwelling catheter method	left femoral artery	0		0					65463	151
SS.LEW-(D8Rat56-D8Rat51)/Ayd	mean arterial blood pressure	controlled sodium content diet (2 %) (between 31 and 38 days)	Ariyarajah A, et al., J Hypertens 2004 Aug;22(8):1495-502.	arterial blood pressure trait	male	66 days-74 days	9			197.0	mmHg	5.0	15.0	radiotelemetry		0		0					65471	589
SS/JrHsdMcwi	plasma renin activity level	controlled sodium content diet (0.4 %) (for 35 days) and furosemide (10 mg/kg)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	renin activity	female	95 days	7			4.7	ng/ml/h	1.6	4.23	ex vivo blood analysis		0		0					65473	151
SS/Jr	mean arterial blood pressure	controlled sodium content diet (2 %) (for 63 days)	Moujahidine M, et al., Hypertens Res 2004 Mar;27(3):203-12.	arterial blood pressure trait	male	98 days	16		serial mean	171.0	mmHg	4.0	16.0	radiotelemetry		120		0			average of 6hr		65475	610
BN/NHsdMcwi	plasma renin activity level	controlled sodium content diet (0.4 %) (for 35 days) and furosemide (10 mg/kg)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	renin activity	female	95 days	11			9.6	ng/ml/h	1.0	3.32	ex vivo blood analysis		0		0					65474	151
SS-Chr 19SHR/Rkb	single kidney wet weight to body weight ratio	controlled sodium content diet (0.2 %) (for 56 days)	Wendt N, et al., J Hypertens. 2007 Jan;25(1):95-102.	kidney mass	male	98 days	20			3.1	g/kg	0.06	0.27	post excision weight measurement		0		0					66088	669
SS-Chr 19SHR/Rkb	heart right ventricle weight to body weight ratio	controlled sodium content diet (4 %) (for 56 days)	Wendt N, et al., J Hypertens. 2007 Jan;25(1):95-102.	heart right ventricle mass	male	98 days	20			0.57	mg/g	0.03	0.13	post excision weight measurement		0		0					66093	669
SS-Chr 5BN-Cyp4a2em1Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	3			9.13	mEq/d	0.61	1.06	automated urine analysis				0				-	66834	717
SS-Ncf2em1Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	5			10.7	mEq/d	0.99	2.21	automated urine analysis				0				-	66831	717
SS-Apoeem7Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	3			12.51	mEq/d	2.26	3.92	automated urine analysis				0				-	66836	717
SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi-/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	1			12.12	mEq/d			automated urine analysis				0				-	66835	717
SS-Cybaem1Mcwi-/-	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	6			9.8	mEq/d	1.62	3.97	automated urine analysis				0				-	66837	717
SS-Nox4em2Mcwi-/-	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	5			9.51	mEq/d	0.72	1.61	automated urine analysis				0				-	66853	717
SS-Renem1Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	4			7.2	mEq/d	0.99	1.98	automated urine analysis				0				-	66855	717
SS-Nckap5em3Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	2			10.65	mEq/d	0.47	0.67	automated urine analysis				0				-	66867	717
SS-Mas1em1Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	2			10.91	mEq/d	2.02	2.85	automated urine analysis				0				-	66869	717
SS-Mmp2em1Mcwi-/-	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	6			24.91	mg/d	4.8	11.75	automated urine analysis				0				-	66875	717
SS-Nckap5em1Mcwi-/-	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	7			66.56	mg/d	21.67	57.33	automated urine analysis				0				-	66885	717
SS-Gpr183em2Mcwi-/-	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	9			84.78	mg/d	11.45	34.35	automated urine analysis				0				-	66887	717
SS-Gpr183em3Mcwi+/+	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	4			56.31	mg/d	13.79	27.57	automated urine analysis				0				-	66904	717
SS-Nckap5em2Mcwi+/+	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	2			76.07	mg/d	1.64	2.32	automated urine analysis				0				-	66907	717
SS-Ets1em1Mcwi-/+	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	9			14.6	mg/d	3.91	11.72	automated urine analysis				0				-	66917	717
SS-Itga9em1Mcwi+/+	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	4			34.92	mg/d	4.36	8.71	automated urine analysis				0				-	66923	717
SS-Mthfrem1Mcwi-/+	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	8			73.13	mg/d	19.06	53.91	automated urine analysis				0				-	66929	717
SS-Acad10em2Mcwi+/+	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	5			41.87	mg/d	14.26	31.89	automated urine analysis				0				-	66931	717
SS-Ncf2em1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	6	1/3 systolic pressure + 2/3 diastolic pressure		127.17	mmHg	6.48	15.88	radiotelemetry	carotid artery			0				-	66934	717
SS-Nox4em2Mcwi-/+	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	2			42.62	mg/d	6.61	9.34	automated urine analysis				0				-	66932	717
FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	1/3 systolic pressure + 2/3 diastolic pressure		124.75	mmHg	5.48	10.97	radiotelemetry	carotid artery			0				-	66935	717
SS-Mas1em1Mcwi+/+	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	2			82.56	mg/d	1.95	2.75	automated urine analysis				0				-	66930	717
SS-Rag1em1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	1/3 systolic pressure + 2/3 diastolic pressure		127.5	mmHg	4.09	8.19	radiotelemetry	carotid artery			0				-	66938	717
SS-Ulk4em3Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	1/3 systolic pressure + 2/3 diastolic pressure		174.25	mmHg	16.92	33.84	radiotelemetry	carotid artery			0				-	66940	717
SS-Tgfb1em3Mcwi+/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	3	1/3 systolic pressure + 2/3 diastolic pressure		119.67	mmHg	10.14	17.56	radiotelemetry	carotid artery			0				-	66945	717
SS-Ncf2em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	5	1/3 systolic pressure + 2/3 diastolic pressure		126.2	mmHg	6.27	14.03	radiotelemetry	carotid artery			0				-	66953	717
SS-Cybaem1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	5	1/3 systolic pressure + 2/3 diastolic pressure		124.0	mmHg	8.62	19.27	radiotelemetry	carotid artery			0				-	66958	717
SS-Nox4em2Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	3	1/3 systolic pressure + 2/3 diastolic pressure		120.67	mmHg	3.38	5.86	radiotelemetry	carotid artery			0				-	66965	717
SS-Rag1em1Mcwi-/-	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	3			1.0	g	0.07	0.12	post excision weight measurement				0				-	66998	717
SS-Mthfrem1Mcwi+/+	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	1			1.08	g			post excision weight measurement				0				-	67003	717
SS-Ulk4em3Mcwi-/-	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	4			1.26	g	0.05	0.11	post excision weight measurement				0				-	67000	717
SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi+/+	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	2			1.19	g	0.0	0.0	post excision weight measurement				0				-	67015	717
SS-Apoeem7Mcwi+/+	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	3			1.16	g	0.06	0.1	post excision weight measurement				0				-	67018	717
SS-Apoeem7Mcwi-/-	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	5			1.1	g	0.03	0.06	post excision weight measurement				0				-	67023	717
SS-Tfdp2em2Mcwi-/-	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	3			1.17	g	0.01	0.02	post excision weight measurement				0				-	67042	717
SS-Nox4em2Mcwi-/+	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	2			1.04	g	0.0	0.0	post excision weight measurement				0				-	67054	717
SS-Gpr183em2Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			335.5	beats/min	6.5	9.19	radiotelemetry	carotid artery			0				-	67074	717
FHH-Chr 1BN-Sorcs1em1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	4			366.25	beats/min	23.14	46.28	radiotelemetry	carotid artery			0				-	67076	717
SS-Apoeem7Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	3			364.0	beats/min	12.29	21.28	radiotelemetry	carotid artery			0				-	67084	717
SS-Rag1em2Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	6			343.0	beats/min	14.92	36.56	radiotelemetry	carotid artery			0				-	67088	717
SS-Nox4em2Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	3			374.33	beats/min	5.7	9.87	radiotelemetry	carotid artery			0				-	67087	717
SS-Gpr183em3Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	3			345.67	beats/min	10.27	17.79	radiotelemetry	carotid artery			0				-	67086	717
SS-Nckap5em2Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			341.0	beats/min	11.0	15.56	radiotelemetry	carotid artery			0				-	67089	717
SS-Rag1em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	4			353.0	beats/min	22.92	45.83	radiotelemetry	carotid artery			0				-	67093	717
SS-Chr 5BN-Cyp4a2em1Mcwi-/+	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	3			360.67	beats/min	2.67	4.62	radiotelemetry	carotid artery			0				-	67095	717
SS-Itga9em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	3			374.0	beats/min	5.29	9.17	radiotelemetry	carotid artery			0				-	67105	717
SS.LEW-(D10Chm224-D10Chm6)/Ayd	heart left ventricle weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	heart left ventricle mass	male	98 days	11			2.78	mg/g	0.04	0.13	post excision weight measurement		0		0					64886	226
SS.LEW-(D18Chm91-D18Rat67)/Ayd	heart left ventricle weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	heart left ventricle mass	male	98 days	5			2.7	mg/g	0.1	0.22	post excision weight measurement		0		0					64896	226
SS.LEW-(D10Chm128-D10Chm169)/Ayd	heart left ventricle weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	heart left ventricle mass	male	98 days	8			2.97	mg/g	0.08	0.23	post excision weight measurement		0		0					64914	226
BN/NHsdMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (0.4 %) (for 28 days) then controlled sodium content diet (8 %) (for 30 days) then controlled exposure to ambient light (for 12 hours) then controlled exposure to darkness (for 12 hours)	Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15.	arterial blood pressure trait	male	91 days-93 days	42		continuous mean	4.5	mmHg	2.0	12.96	vascular indwelling catheter method	femoral artery	0.0		0		left femoral artery	increase		64928	229
SS/Jr	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 39 and 40 days)	Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.	arterial blood pressure trait	male	107 days-109 days	3			228.2	mmHg	2.6	4.5	intra-aortic abdominal radiotelemetry		86400		0					65047	283
SS/Jr	diastolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 27 and 28 days)	Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.	arterial blood pressure trait	male	67 days-69 days	5			125.2	mmHg	3.0	6.71	intra-aortic abdominal radiotelemetry		86400		0					65057	283
SS.SR-(D3Arb14-D3Mco36)/Mco	diastolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 39 and 40 days)	Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.	arterial blood pressure trait	male	107 days-109 days	4			157.5	mmHg	3.3	6.6	intra-aortic abdominal radiotelemetry		86400		0					65064	283
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco	diastolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 9 and 10 days)	Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.	arterial blood pressure trait	male	76 days-78 days	5			110.2	mmHg	2.0	4.47	intra-aortic abdominal radiotelemetry		86400		0					65062	283
SS-Nckap5em3Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			356.5	beats/min	12.5	17.68	radiotelemetry	carotid artery			0				-	67110	717
FHH-Chr 1BN-Sorcs1em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			381.0	beats/min	1.0	1.41	radiotelemetry	carotid artery			0				-	67126	717
SS-Mthfrem1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	1			348.0	beats/min			radiotelemetry	carotid artery			0				-	67125	717
SS-Gpr183em2Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			379.0	beats/min	13.0	18.38	radiotelemetry	carotid artery			0				-	67134	717
SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi-/+	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	1			353.0	beats/min			radiotelemetry	carotid artery			0				-	67139	717
SS-Gpr183em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	3			373.33	beats/min	14.66	25.38	radiotelemetry	carotid artery			0				-	67142	717
SS-Tfdp2em2Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	3			380.33	beats/min	38.35	66.43	radiotelemetry	carotid artery			0				-	67164	717
SS-Mthfrem1Mcwi-/+	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	8			353.57	beats/min	9.89	27.96	radiotelemetry	carotid artery			0				-	67173	717
SS-Acad10em2Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	5			374.6	beats/min	8.52	19.05	radiotelemetry	carotid artery			0				-	67175	717
SS-Mas1em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			348.5	beats/min	6.5	9.19	radiotelemetry	carotid artery			0				-	67174	717
LEW/Crl	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	5			2.96	beats/min	11.93	26.67	vascular fluid filled catheter				0					51680	481
FHH/EurMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	8			-11.7	beats/min	12.08	34.18	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51700	481
FHH/EurMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	5			-3.72	beats/min	14.86	33.24	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51703	481
BN/NHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	4			-74.95	beats/min	19.95	39.89	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51701	481
SS-Chr 9BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	6			-90.84	beats/min	15.38	37.66	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51711	481
FHH/EurMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	6			-36.4	beats/min	20.58	50.41	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51714	481
SS-Chr 9BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	5			-21.04	beats/min	12.68	28.35	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51725	481
Hsd:SD	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	glomerular filtration trait	male	87 days-120 days	11			2.61	ml/min	0.23	0.77	urine creatinine analysis				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	51747	481
SS/JrHsdMcwi	urine total protein excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	total urine protein amount	male	87 days-120 days	21			53.74	mg/d	5.94	27.24	automated urine analysis				0				Moms and pups used in studies were fed Teklad	51750	481
SS-Chr 18BN/Mcwi	urine total protein excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	total urine protein amount	female	87 days-120 days	8			23.12	mg/d	6.52	18.44	automated urine analysis				0				Moms and pups used in studies were fed Teklad	51753	481
GH/OmrMcwi	urine total protein excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	total urine protein amount	male	87 days-120 days	8			15.69	mg/d	3.09	8.73	automated urine analysis				0				Moms and pups used in studies were fed Teklad	51756	481
SHR/NCrl	urine total protein excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	total urine protein amount	male	87 days-120 days	9			24.02	mg/d	3.75	11.24	automated urine analysis				0				Moms and pups used in studies were fed Teklad	51755	481
BN/NHsdMcwi	urine total protein excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	total urine protein amount	female	87 days-120 days	10			19.71	mg/d	4.56	14.41	automated urine analysis				0				Moms and pups used in studies were fed Teklad	51762	481
LEW/Crl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	5			17.03	mmHg	2.14	4.79	vascular fluid filled catheter				0					51764	481
WKY/NCrl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	7			21.82	mmHg	4.54	12.02	vascular fluid filled catheter				0					51784	481
BN/NHsdMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	4			30.33	mmHg	2.51	5.03	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51778	481
LEW/Crl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	9			7.38	mmHg	3.34	10.01	vascular fluid filled catheter				0					51786	481
FHH/EurMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	8			15.53	beats/min	17.94	50.74	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51795	481
FHH/EurMcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	glomerular filtration trait	male	87 days-120 days	8			1.77	ml/min	0.16	0.45	urine creatinine analysis				0				Moms and pups used in studies were fed Dyets	51803	481
FHH/EurMcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	7			116.75	mmHg	1.54	4.07	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51820	481
SS-Chr 20BN/Mcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	renin activity	female	87 days-120 days	9			1.75	ng/ml/h	0.31	0.92	radioimmunoassay				0				Moms and pups used in studies were fed Teklad	51834	481
SS/JrHsdMcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	renin activity	male	87 days-120 days	13			0.43	ng/ml/h	0.08	0.29	radioimmunoassay				0				Moms and pups used in studies were fed Teklad	51833	481
SS-Chr 9BN/Mcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	renin activity	female	87 days-120 days	14			1.08	ng/ml/h	0.12	0.45	radioimmunoassay				0				Moms and pups used in studies were fed Teklad	51840	481
FHH/EurMcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	renin activity	male	87 days-120 days	5			4.01	ng/ml/h	1.09	2.43	radioimmunoassay				0				Moms and pups used in studies were fed Teklad	51843	481
BN/NHsdMcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	renin activity	male	87 days-120 days	3			2.06	ng/ml/h	0.69	1.19	radioimmunoassay				0				Moms and pups used in studies were fed Teklad	51844	481
FHH/EurMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	5			-25.56	beats/min	21.49	48.06	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51847	481
SS-Chr 16BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	7			-26.49	beats/min	16.87	44.63	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51849	481
GH/OmrMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	8			22.21	beats/min	6.03	17.04	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51855	481
SHR/NCrl	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	8			-8.33	beats/min	29.02	82.09	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51856	481
BN/NHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	4			-7.05	beats/min	10.76	21.52	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51858	481
SS/JrHsdMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	12			16.35	mmHg	2.77	9.58	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51869	481
BN/NHsdMcwi	urine sodium excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	urine sodium amount	female	87 days-120 days	10			10.9	mEq/d	0.8	2.54	flame atomic emission spectrometry				0				Moms and pups used in studies were fed Teklad	51894	481
F344/DuCrl	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	blood creatinine amount	male	87 days-120 days	7			0.29	mg/dl	0.01	0.02	radioimmunoassay				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51896	481
F344/DuCrl	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	blood creatinine amount	female	87 days-120 days	9			0.22	mg/dl	0.01	0.03	radioimmunoassay				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51898	481
SS-Chr 16BN/Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	blood creatinine amount	female	87 days-120 days	5			0.31	mg/dl	0.02	0.04	radioimmunoassay				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51902	481
FHH/EurMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	2			21.3	beats/min	54.9	77.64	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51921	481
SS-Chr 9BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	15			-30.67	beats/min	12.69	49.15	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51925	481
SS-Chr 16BN/Mcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	glomerular filtration trait	male	87 days-120 days	6			2.03	ml/min	0.15	0.38	urine creatinine analysis				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51935	481
SS-Chr 18BN/Mcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	glomerular filtration trait	female	87 days-120 days	1			1.05	ml/min			urine creatinine analysis				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51934	481
SS-Chr 16BN/Mcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	glomerular filtration trait	female	87 days-120 days	4			1.44	ml/min	0.11	0.22	urine creatinine analysis				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51933	481
SS/JrHsdMcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	glomerular filtration trait	male	87 days-120 days	14			1.64	ml/min	0.17	0.64	urine creatinine analysis				0				Moms and pups used in studies were fed Teklad	51944	481
SS-Chr 20BN/Mcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	glomerular filtration trait	female	87 days-120 days	12			0.96	ml/min	0.09	0.3	urine creatinine analysis				0				Moms and pups used in studies were fed Teklad	51945	481
SS-Chr 18BN/Mcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	glomerular filtration trait	female	87 days-120 days	5			1.39	ml/min	0.1	0.23	urine creatinine analysis				0				Moms and pups used in studies were fed Teklad	51947	481
SS-Chr 9BN/Mcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	glomerular filtration trait	male	87 days-120 days	13			1.13	ml/min	0.2	0.73	urine creatinine analysis				0				Moms and pups used in studies were fed Teklad	51948	481
SS-Chr 9BN/Mcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	glomerular filtration trait	female	87 days-120 days	14			0.77	ml/min	0.16	0.61	urine creatinine analysis				0				Moms and pups used in studies were fed Teklad	51951	481
SHR/NCrl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	1			24.43	mmHg			vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51965	481
SS-Chr 20BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	15			25.27	mmHg	3.22	12.48	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51966	481
SS-Chr 18BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	6			-0.9	mmHg	1.72	4.22	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51967	481
FHH/EurMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	7			13.53	mmHg	3.99	10.56	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51969	481
Crl:CD(SD)	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	blood creatinine amount	male	87 days-120 days	6			0.32	mg/dl	0.02	0.05	radioimmunoassay				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51984	481
F344/DuCrl	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	blood creatinine amount	male	87 days-120 days	5			0.29	mg/dl	0.02	0.05	radioimmunoassay				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51985	481
SS-Chr 20BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	14			122.5	mmHg	2.84	10.64	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	52006	481
FHH/EurMcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	4			137.89	mmHg	7.62	15.25	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	52007	481
SS-Chr 9BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	14			123.13	mmHg	1.84	6.88	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	52004	481
SS-Chr 18BN/Mcwi	urine sodium excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	urine sodium amount	male	87 days-120 days	8			13.61	mEq/d	0.49	1.38	flame atomic emission spectrometry				0				Moms and pups used in studies were fed Dyets	52010	481
SS-Chr 16BN/Mcwi	urine sodium excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	urine sodium amount	female	87 days-120 days	6			14.22	mEq/d	0.96	2.35	flame atomic emission spectrometry				0				Moms and pups used in studies were fed Dyets	52013	481
BN/NHsdMcwi	urine sodium excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	urine sodium amount	male	87 days-120 days	3			12.33	mEq/d	1.71	2.97	flame atomic emission spectrometry				0				Moms and pups used in studies were fed Dyets	52021	481
WKY/NCrl	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	glomerular filtration trait	male	87 days-120 days	9			1.5	ml/min	0.15	0.45	urine creatinine analysis				0					52027	481
LEW/Crl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	7			1.21	mmHg	4.28	11.33	vascular fluid filled catheter				0					52024	481
SS-Chr 18BN/Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	blood creatinine amount	male	87 days-120 days	7			0.31	mg/dl	0.02	0.06	radioimmunoassay				0				Moms and pups used in studies were fed Dyets	52035	481
SS-Chr 16BN/Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	blood creatinine amount	female	87 days-120 days	6			0.35	mg/dl	0.01	0.03	radioimmunoassay				0				Moms and pups used in studies were fed Dyets	52038	481
F344/DuCrl	urine total protein excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	total urine protein amount	female	87 days-120 days	10			24.49	mg/d	4.28	13.53	automated urine analysis				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	52063	481
WKY/NCrl	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	9			-33.41	beats/min	13.0	39.01	vascular fluid filled catheter				0					52074	481
WKY/NCrl	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	9			-73.2	beats/min	18.38	55.13	vascular fluid filled catheter				0					52078	481
SS-Chr 9BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	9			129.82	mmHg	3.64	10.92	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	52082	481
WKY/NCrl	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	7			-35.03	beats/min	21.41	56.65	vascular fluid filled catheter				0					52081	481
BN/NHsdMcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	8			104.93	mmHg	2.81	7.93	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	52091	481
BN/NHsdMcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	4			104.25	mmHg	3.14	6.27	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	52092	481
FHH-Chr 12BN/Mcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	female	80 days-99 days	10			157.28	mg/d	60.1	190.06	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52094	482
FHH-Chr 15BN/Mcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	male	80 days-99 days	9			232.75	mg/d	44.36	133.08	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52095	482
FHH-Chr 8BN/Mcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	female	80 days-99 days	7			65.01	mg/d	9.0	23.82	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52096	482
FHH-Chr 5BN/Mcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	female	80 days-99 days	6			110.21	mg/d	29.1	71.27	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52100	482
FHH/EurMcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	female	80 days-99 days	16			170.33	mg/d	49.67	198.67	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52097	482
FHH-Chr 3BN/Mcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	female	80 days-99 days	2			259.8	mg/d	89.85	127.07	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52099	482
FHH-Chr 12BN/Mcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	male	80 days-99 days	11			368.02	mg/d	45.8	151.92	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52113	482
FHH/EurMcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	male	80 days-99 days	48			472.36	mg/d	30.23	209.46	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52115	482
FHH-Chr 4BN/Mcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	female	80 days-99 days	9			168.35	mg/d	63.34	190.01	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52127	482
BN/NHsdMcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	female	80 days-99 days	11			39.43	mg/d	8.21	27.23	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52135	482
SS-Chr 9BN/Mcwi	creatinine clearance	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	glomerular filtration trait	male	80 days-99 days	8			1.85	ml/min	0.19	0.55	urine creatinine analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52145	482
SS.BN-(D12Arb13-D12Rat79)/Mcwi	creatinine clearance	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	glomerular filtration trait	female	80 days-99 days	8			1.68	ml/min	0.46	1.31	urine creatinine analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52146	482
SS-Chr 17BN/Mcwi	creatinine clearance	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	glomerular filtration trait	male	80 days-99 days	5			2.41	ml/min	0.57	1.27	urine creatinine analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52151	482
FHH-Chr 5BN/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	female	80 days-99 days	6			23.17	mEq/d	2.06	5.05	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52786	482
FHH-Chr 6BN/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	female	80 days-99 days	8			15.39	mEq/d	2.33	6.6	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52791	482
FHH-Chr 15BN/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	female	80 days-99 days	7			17.44	mEq/d	3.27	8.66	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52802	482
FHH-Chr 16BN/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	female	80 days-99 days	7			8.59	mEq/d	1.43	3.78	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52808	482
FHH-Chr XBN/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	female	80 days-99 days	7			20.79	mEq/d	0.9	2.37	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52822	482
FHH-Chr 7BN/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	male	80 days-99 days	11			14.23	mEq/d	3.75	12.43	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52824	482
SS-Chr 10BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	male	80 days-99 days	10			171.08	mmHg	6.65	21.04	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52829	482
SS-Chr 16BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	female	80 days-99 days	8			135.4	mmHg	3.37	9.54	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52846	482
SS-Chr 20BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	male	80 days-99 days	7			147.43	mmHg	7.77	20.57	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52853	482
SS.BN-(D8Rat163-D8Rat81)/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	male	80 days-99 days	20			156.0	mmHg	7.15	31.98	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52872	482
FHH-Chr 15BN/Mcwi	plasma renin activity level	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	renin activity	male	80 days-99 days	9			2.92	ng/ml/h	0.71	2.13	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52879	482
FHH-Chr 12BN/Mcwi	plasma renin activity level	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	renin activity	female	80 days-99 days	7			7.44	ng/ml/h	1.44	3.8	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52878	482
FHH-Chr 6BN/Mcwi	plasma renin activity level	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	renin activity	female	80 days-99 days	6			3.2	ng/ml/h	0.43	1.06	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52889	482
FHH-Chr 13BN/Mcwi	plasma renin activity level	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	renin activity	female	80 days-99 days	7			8.07	ng/ml/h	0.72	1.91	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52892	482
FHH-Chr 20BN/Mcwi	plasma renin activity level	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	renin activity	male	80 days-99 days	1			1.4	ng/ml/h			radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52893	482
FHH/EurMcwi	plasma renin activity level	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	renin activity	male	80 days-99 days	38			2.57	ng/ml/h	0.36	2.21	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52899	482
FHH-Chr 12BN/Mcwi	plasma renin activity level	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	renin activity	male	80 days-99 days	10			1.71	ng/ml/h	0.17	0.52	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52897	482
FHH-Chr 1BN/Mcwi	plasma renin activity level	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	renin activity	male	80 days-99 days	7			3.1	ng/ml/h	0.58	1.53	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52907	482
FHH-Chr 11BN/Mcwi	plasma renin activity level	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	renin activity	male	80 days-99 days	3			1.02	ng/ml/h	0.4	0.69	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52912	482
FHH-Chr 4BN/Mcwi	plasma renin activity level	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	renin activity	female	80 days-99 days	8			11.17	ng/ml/h	2.91	8.22	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52911	482
FHH-Chr XBN/Mcwi	plasma renin activity level	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	renin activity	female	80 days-99 days	5			4.63	ng/ml/h	0.97	2.16	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52920	482
FHH-Chr 9BN/Mcwi	plasma renin activity level	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	renin activity	male	80 days-99 days	4			2.48	ng/ml/h	0.69	1.38	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52921	482
SS-Chr 14BN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	female	80 days-99 days	11			0.88	mEq/d	0.09	0.29	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52929	482
SS-Chr 5BN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	female	80 days-99 days	8			1.03	mEq/d	0.09	0.27	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52940	482
SS-Chr 5BN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	male	80 days-99 days	10			1.33	mEq/d	0.09	0.28	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52942	482
SS-Chr 3BN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	female	80 days-99 days	7			1.04	mEq/d	0.11	0.3	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52950	482
SS-Chr 1BN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	male	80 days-99 days	20			1.07	mEq/d	0.08	0.34	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52958	482
SS-Chr 20BN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	male	80 days-99 days	9			0.95	mEq/d	0.07	0.2	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52951	482
SS-Chr XBN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	female	80 days-99 days	7			1.27	mEq/d	0.14	0.38	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52959	482
SS-Chr 4BN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	male	80 days-99 days	7			1.08	mEq/d	0.21	0.56	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52962	482
SS.BN-(D8Rat163-D8Rat81)/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	male	80 days-99 days	21			1.14	mEq/d	0.05	0.23	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52970	482
SS-Chr 1BN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	female	80 days-99 days	19			0.93	mEq/d	0.06	0.27	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52961	482
SS-Chr 19BN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	female	80 days-99 days	8			0.81	mEq/d	0.08	0.23	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52967	482
SS-Chr XBN/Mcwi	creatinine clearance	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	glomerular filtration trait	female	80 days-99 days	3			1.6	ml/min	0.34	0.59	urine creatinine analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52173	482
SS-Chr 12BN/Mcwi	creatinine clearance	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	glomerular filtration trait	female	80 days-99 days	3			2.21	ml/min	0.03	0.06	urine creatinine analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52185	482
SS-Chr 14BN/Mcwi	plasma creatinine level	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	blood creatinine amount	female	80 days-99 days	9			0.3	mg/dl	0.01	0.04	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52192	482
SS.BN-(D12Arb13-D12Rat79)/Mcwi	plasma creatinine level	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	blood creatinine amount	female	80 days-99 days	8			0.34	mg/dl	0.04	0.1	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52195	482
SS-Chr XBN/Mcwi	creatinine clearance	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	glomerular filtration trait	male	80 days-99 days	3			2.43	ml/min	0.72	1.25	urine creatinine analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52188	482
SS-Chr 16BN/Mcwi	plasma creatinine level	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	blood creatinine amount	female	80 days-99 days	9			0.42	mg/dl	0.02	0.05	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52207	482
SS-Chr 20BN/Mcwi	plasma creatinine level	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	blood creatinine amount	male	80 days-99 days	7			0.36	mg/dl	0.02	0.05	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52214	482
SS-Chr 18BN/Mcwi	plasma creatinine level	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	blood creatinine amount	female	80 days-99 days	8			0.33	mg/dl	0.03	0.09	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52223	482
SS-Chr XBN/Mcwi	plasma creatinine level	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	blood creatinine amount	male	80 days-99 days	3			0.4	mg/dl	0.07	0.13	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52237	482
FHH-Chr 15BN/Mcwi	plasma creatinine level	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	blood creatinine amount	male	80 days-99 days	9			0.32	mg/dl	0.01	0.03	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52244	482
FHH-Chr 6BN/Mcwi	plasma creatinine level	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	blood creatinine amount	female	80 days-99 days	5			0.38	mg/dl	0.05	0.11	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52254	482
FHH-Chr 1BN/Mcwi	plasma creatinine level	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	blood creatinine amount	male	80 days-99 days	7			0.35	mg/dl	0.03	0.08	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52272	482
FHH-Chr 9BN/Mcwi	plasma creatinine level	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	blood creatinine amount	female	80 days-99 days	3			0.5	mg/dl	0.2	0.34	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52280	482
FHH-Chr XBN/Mcwi	plasma creatinine level	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	blood creatinine amount	male	80 days-99 days	6			0.61	mg/dl	0.08	0.2	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52278	482
BN/NHsdMcwi	plasma creatinine level	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	blood creatinine amount	male	80 days-99 days	8			0.24	mg/dl	0.03	0.07	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52283	482
BN/NHsdMcwi	plasma creatinine level	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	blood creatinine amount	female	80 days-99 days	7			0.33	mg/dl	0.03	0.08	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52284	482
LE/BluGill	creatinine clearance	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	glomerular filtration trait	male	80 days-99 days	6			2.56	ml/min	0.2	0.5	urine creatinine analysis				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	52291	482
FHH-Chr 5BN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	female	80 days-99 days	6			1.25	mEq/d	0.12	0.3	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52298	482
FHH-Chr 2BN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	male	80 days-99 days	5			1.34	mEq/d	0.07	0.15	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52318	482
FHH-Chr 1BN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	female	80 days-99 days	10			0.94	mEq/d	0.09	0.27	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52338	482
FHH-Chr 2BN/Mcwi	creatinine clearance	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	glomerular filtration trait	female	80 days-99 days	5			1.71	ml/min	0.2	0.44	urine creatinine analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52346	482
FHH-Chr 20BN/Mcwi	creatinine clearance	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	glomerular filtration trait	female	80 days-99 days	6			2.06	ml/min	0.39	0.95	urine creatinine analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52357	482
FHH-Chr 5BN/Mcwi	creatinine clearance	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	glomerular filtration trait	male	80 days-99 days	7			1.6	ml/min	0.12	0.32	urine creatinine analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52351	482
FHH-Chr 13BN/Mcwi	creatinine clearance	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	glomerular filtration trait	male	80 days-99 days	10			1.17	ml/min	0.23	0.73	urine creatinine analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52355	482
FHH-Chr 3BN/Mcwi	creatinine clearance	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	glomerular filtration trait	male	80 days-99 days	3			0.68	ml/min	0.25	0.44	urine creatinine analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52362	482
FHH-Chr 10BN/Mcwi	creatinine clearance	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	glomerular filtration trait	female	80 days-99 days	7			1.82	ml/min	0.35	0.94	urine creatinine analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52366	482
FHH-Chr 7BN/Mcwi	creatinine clearance	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	glomerular filtration trait	female	80 days-99 days	7			1.44	ml/min	0.23	0.6	urine creatinine analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52377	482
FHH-Chr 16BN/Mcwi	creatinine clearance	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	glomerular filtration trait	male	80 days-99 days	7			1.55	ml/min	0.35	0.92	urine creatinine analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52384	482
FHH-Chr 19BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine albumin amount	male	80 days-99 days	7			227.43	mg/d	44.77	118.45	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52390	482
FHH-Chr 19BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine albumin amount	female	80 days-99 days	8			31.83	mg/d	11.92	33.71	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52396	482
FHH-Chr 18BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine albumin amount	female	80 days-99 days	9			48.46	mg/d	29.49	88.47	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52406	482
FHH/EurMcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine albumin amount	male	80 days-99 days	48			183.29	mg/d	13.89	96.23	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52407	482
FHH-Chr 1BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine albumin amount	male	80 days-99 days	10			68.56	mg/d	16.62	52.55	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52415	482
FHH-Chr 10BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine albumin amount	male	80 days-99 days	6			264.36	mg/d	29.33	71.84	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52425	482
FHH-Chr 9BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine albumin amount	female	80 days-99 days	5			134.79	mg/d	42.57	95.18	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52423	482
SS-Chr 7BN/Mcwi	plasma renin activity level	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	renin activity	male	80 days-99 days	9			0.51	ng/ml/h	0.12	0.37	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52446	482
SS-Chr 5BN/Mcwi	plasma renin activity level	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	renin activity	female	80 days-99 days	7			0.44	ng/ml/h	0.08	0.2	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52448	482
SS-Chr 15BN/Mcwi	plasma renin activity level	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	renin activity	male	80 days-99 days	7			0.28	ng/ml/h	0.02	0.05	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52453	482
SS-Chr 13BN/Mcwi	plasma renin activity level	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	renin activity	female	80 days-99 days	17			1.13	ng/ml/h	0.29	1.2	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52457	482
SS.BN-(D8Rat163-D8Rat81)/Mcwi	plasma renin activity level	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	renin activity	male	80 days-99 days	18			0.66	ng/ml/h	0.14	0.58	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52478	482
FHH-Chr 15BN/Mcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	male	80 days-99 days	9			383.93	beats/min	7.94	23.83	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52485	482
FHH-Chr 20BN/Mcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	male	80 days-99 days	7			386.33	beats/min	10.29	27.22	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52499	482
FHH-Chr 4BN/Mcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	male	80 days-99 days	5			446.87	beats/min	8.17	18.26	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52514	482
FHH-Chr 11BN/Mcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	male	80 days-99 days	4			431.62	beats/min	7.42	14.85	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52518	482
FHH-Chr 9BN/Mcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	female	80 days-99 days	4			437.66	beats/min	5.03	10.06	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52521	482
FHH-Chr 9BN/Mcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	male	80 days-99 days	4			409.54	beats/min	10.2	20.4	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52527	482
FHH-Chr 2BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	female	80 days-99 days	5			156.33	mmHg	11.05	24.71	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52538	482
FHH-Chr 5BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	male	80 days-99 days	7			174.07	mmHg	8.96	23.69	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52543	482
FHH-Chr 8BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	male	80 days-99 days	3			159.61	mmHg	9.53	16.51	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52544	482
FHH-Chr 13BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	male	80 days-99 days	10			188.54	mmHg	5.26	16.64	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52547	482
FHH/EurMcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	male	80 days-99 days	48			181.54	mmHg	2.9	20.07	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52552	482
FHH-Chr 1BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	male	80 days-99 days	9			166.93	mmHg	4.8	14.41	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52560	482
FHH-Chr 11BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	male	80 days-99 days	4			188.98	mmHg	4.83	9.66	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52565	482
FHH-Chr 7BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	female	80 days-99 days	9			148.65	mmHg	7.47	22.42	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52569	482
FHH-Chr 9BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	female	80 days-99 days	4			170.24	mmHg	5.85	11.71	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52568	482
BN/NHsdMcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	male	80 days-99 days	8			120.84	mmHg	2.6	7.37	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52571	482
FHH-Chr 16BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	male	80 days-99 days	8			165.26	mmHg	12.62	35.7	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52576	482
SS-Chr 5BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine albumin amount	male	80 days-99 days	10			27.89	mg/d	5.0	15.81	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52595	482
SS-Chr 20BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine albumin amount	male	80 days-99 days	9			44.12	mg/d	8.7	26.09	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52604	482
SS-Chr 4BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine albumin amount	male	80 days-99 days	7			53.64	mg/d	9.34	24.71	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52615	482
SS-Chr 4BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine albumin amount	female	80 days-99 days	8			11.71	mg/d	2.97	8.4	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52621	482
SS-Chr 2BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine albumin amount	male	80 days-99 days	10			73.9	mg/d	13.02	41.18	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52628	482
SS-Chr 7BN/Mcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	female	80 days-99 days	10			413.46	beats/min	4.88	15.44	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52645	482
SS-Chr 5BN/Mcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	female	80 days-99 days	8			396.82	beats/min	6.28	17.76	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52644	482
SS-Chr 20BN/Mcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	female	80 days-99 days	9			410.8	beats/min	6.42	19.25	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52647	482
SS-Chr 11BN/Mcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	female	80 days-99 days	15			401.61	beats/min	7.22	27.95	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52656	482
SS-Chr 11BN/Mcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	male	80 days-99 days	14			378.79	beats/min	10.47	39.16	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52658	482
SS-Chr XBN/Mcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	female	80 days-99 days	5			432.4	beats/min	14.46	32.33	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52663	482
SS/JrHsdMcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	female	80 days-99 days	9			416.02	beats/min	6.59	19.78	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52667	482
SS.BN-(D8Rat163-D8Rat81)/Mcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	female	80 days-99 days	11			396.87	beats/min	4.2	13.92	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52668	482
SS-Chr 4BN/Mcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	male	80 days-99 days	7			399.08	beats/min	14.32	37.89	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52666	482
SS-Chr 12BN/Mcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	male	80 days-99 days	7			358.72	beats/min	9.8	25.93	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52670	482
BN/NHsdMcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	female	80 days-99 days	18			384.5	beats/min	7.1	30.12	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52677	482
SS.BN-(D12Arb13-D12Rat79)/Mcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	female	80 days-99 days	10			184.5	mg/d	28.5	90.11	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52685	482
SS-Chr 6BN/Mcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	male	80 days-99 days	9			89.78	mg/d	14.56	43.68	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52688	482
SS-Chr 7BN/Mcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	male	80 days-99 days	11			72.57	mg/d	8.11	26.89	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52691	482
SS-Chr 5BN/Mcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	male	80 days-99 days	10			46.14	mg/d	7.31	23.12	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52695	482
SS-Chr YBN/Mcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	male	80 days-99 days	17			152.58	mg/d	15.5	63.93	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52708	482
SS/JrHsdMcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	female	80 days-99 days	11			161.82	mg/d	34.64	114.9	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52716	482
SS.BN-(D12Arb13-D12Rat79)/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	male	80 days-99 days	12			15.1	mEq/d	1.32	4.57	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52732	482
SS-Chr 17BN/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	female	80 days-99 days	7			20.45	mEq/d	2.52	6.66	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52743	482
SS-Chr 20BN/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	male	80 days-99 days	9			15.96	mEq/d	2.07	6.2	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52755	482
SS-Chr 13BN/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	male	80 days-99 days	16			11.92	mEq/d	1.33	5.31	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52757	482
SS-Chr XBN/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	female	80 days-99 days	7			16.97	mEq/d	1.49	3.94	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52763	482
SS-Chr 1BN/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	female	80 days-99 days	19			10.57	mEq/d	1.46	6.38	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52765	482
SS-Chr 19BN/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	female	80 days-99 days	8			9.12	mEq/d	2.82	7.99	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52771	482
BN/NHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	4			20.6	beats/min	13.45	26.91	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	50513	481
SS-Chr 16BN/Mcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	10			388.73	beats/min	6.4	20.24	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	50527	481
WKY/NCrl	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	6			-71.1	beats/min	33.5	82.05	vascular fluid filled catheter				0					50518	481
SS/JrHsdMcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	renin activity	male	87 days-120 days	3			0.64	ng/ml/h	0.27	0.47	radioimmunoassay				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50536	481
SS-Chr 18BN/Mcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	renin activity	female	87 days-120 days	1			0.67	ng/ml/h			radioimmunoassay				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50539	481
FHH/EurMcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	renin activity	female	87 days-120 days	6			9.02	ng/ml/h	1.47	3.59	radioimmunoassay				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50537	481
Crl:CD(SD)	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	4			3.0	mmHg	3.86	7.72	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	50542	481
WKY/NCrl	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	6			-53.6	beats/min	20.05	49.12	vascular fluid filled catheter				0					50553	481
SS-Chr 18BN/Mcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	renin activity	male	87 days-120 days	5			2.8	ng/ml/h	0.87	1.94	radioimmunoassay				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50565	481
SS-Chr 9BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	9			-34.01	beats/min	27.27	81.82	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50580	481
BN/NHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	4			-24.45	beats/min	31.16	62.33	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50590	481
SS-Chr 16BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	5			-9.39	beats/min	43.01	96.17	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50594	481
FHH/EurMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	9			-1.7	mmHg	1.59	4.78	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	50608	481
GH/OmrMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	6			-0.27	beats/min	11.36	27.82	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	50616	481
BN/NHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	4			-26.25	beats/min	11.9	23.81	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	50623	481
FHH/EurMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	8			-1.4	beats/min	7.97	22.55	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	50622	481
BN/NHsdMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	3			-2.03	mmHg	7.23	12.52	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	50637	481
SS-Chr 16BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	10			136.5	mmHg	3.86	12.21	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	50644	481
SS/JrHsdMcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	4			411.76	beats/min	26.24	52.48	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50667	481
SS-Chr 16BN/Mcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	7			387.4	beats/min	19.95	52.79	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50670	481
SS/JrHsdMcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	3			118.36	mmHg	3.5	6.07	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50673	481
FHH/EurMcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	2			142.46	mmHg	8.89	12.57	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50678	481
SS-Chr 18BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	6			-1.47	beats/min	34.5	84.5	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50684	481
FHH/EurMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	7			-5.23	beats/min	21.31	56.37	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50686	481
LEW/Crl	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	blood creatinine amount	male	87 days-120 days	4			0.29	mg/dl	0.01	0.02	radioimmunoassay				0					50692	481
SS-Chr 20BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	15			0.61	mmHg	1.97	7.64	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50704	481
BN/NHsdMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	7			0.72	mmHg	2.7	7.14	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50706	481
SS-Chr 18BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	1			28.48	beats/min			vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	50720	481
BN/NHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	8			-25.21	beats/min	19.43	54.97	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	50728	481
SHR/NCrl	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	10			149.76	mmHg	4.03	12.74	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50742	481
BN/NHsdMcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	8			101.3	mmHg	2.17	6.14	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50745	481
SS-Chr 18BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	9			29.73	mmHg	2.92	8.76	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	50747	481
GH/OmrMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	6			32.91	mmHg	5.6	13.72	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	50752	481
SS-Chr 16BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	7			-11.26	mmHg	2.11	5.58	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50766	481
SS-Chr 18BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	3			-6.83	mmHg	2.51	4.35	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50765	481
LEW/Crl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	9			-0.91	mmHg	3.29	9.86	vascular fluid filled catheter				0					50770	481
SS-Chr 9BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	12			4.84	mmHg	2.48	8.58	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50779	481
BN/NHsdMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	4			5.65	mmHg	0.84	1.68	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50782	481
SS-Chr 16BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	5			40.43	mmHg	1.89	4.23	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50789	481
SS-Chr 16BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	5			114.24	mmHg	2.67	5.98	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50796	481
FHH/EurMcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	7			140.46	mmHg	4.67	12.37	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50795	481
SS-Chr 16BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	7			119.61	mmHg	1.83	4.85	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50798	481
FHH/EurMcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	8			142.26	mmHg	3.59	10.14	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50799	481
GH/OmrMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	9			-11.35	mmHg	4.78	14.34	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50803	481
SS/JrHsdMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	15			-12.57	mmHg	1.76	6.83	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50801	481
BN/NHsdMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	5			-7.15	mmHg	2.83	6.32	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50812	481
Crl:CD(SD)	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	4			0.91	mmHg	2.27	4.55	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	50818	481
LEW/Crl	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	5			97.54	mmHg	1.66	3.71	vascular fluid filled catheter				0					50837	481
SS-Chr 18BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	6			0.64	mmHg	2.4	5.89	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50840	481
SS-Chr 16BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	2			4.72	mmHg	4.89	6.92	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50843	481
SS/JrHsdMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	3			21.03	mmHg	14.54	25.18	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50841	481
F344/DuCrl	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	9			407.31	beats/min	7.86	23.58	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	50856	481
Crl:CD(SD)	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	7			404.0	beats/min	22.43	59.35	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	50855	481
F344/DuCrl	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	6			385.1	beats/min	13.34	32.69	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	50862	481
Crl:CD(SD)	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	4			-48.95	beats/min	23.61	47.22	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	50865	481
SS-Chr 18BN/Mcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	5			409.57	beats/min	5.76	12.88	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50881	481
Crl:CD(SD)	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	7			35.88	mmHg	3.36	8.9	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	50875	481
F344/DuCrl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	7			31.24	mmHg	2.72	7.19	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	50876	481
SS-Chr 9BN/Mcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	13			395.28	beats/min	9.37	33.79	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50882	481
GH/OmrMcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	8			393.96	beats/min	5.0	14.15	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50884	481
BN/NHsdMcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	5			375.46	beats/min	8.18	18.29	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50889	481
F344/DuCrl	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	6			6.57	beats/min	9.35	22.89	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	50892	481
Crl:CD(SD)	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	4			5.44	beats/min	14.96	29.92	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	50891	481
SS-Chr 18BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	5			28.03	mmHg	6.24	13.95	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50901	481
FHH/EurMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	2			23.96	mmHg	20.35	28.78	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50903	481
SS-Chr 18BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	5			10.88	beats/min	6.24	13.95	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50904	481
SS-Chr 18BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	3			15.12	beats/min	28.47	49.3	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50908	481
FHH/EurMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	7			12.14	beats/min	6.37	16.86	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50906	481
SHR/NCrl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	6			2.79	mmHg	5.37	13.15	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50922	481
SS-Chr 18BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	9			1.42	mmHg	2.41	7.24	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	50925	481
SS-Chr 16BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	5			3.68	mmHg	1.76	3.94	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	50928	481
SS-Chr 9BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	14			136.07	mmHg	3.1	11.61	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50943	481
F344/DuCrl	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	6			-12.2	beats/min	20.46	50.11	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	50953	481
SS-Chr 20BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	15			35.98	mmHg	2.91	11.27	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50962	481
SS-Chr 18BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	6			24.17	mmHg	4.29	10.51	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50964	481
SS-Chr 20BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	14			37.45	beats/min	19.76	73.94	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50986	481
FHH/EurMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	4			36.95	beats/min	7.33	14.67	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50987	481
Crl:CD(SD)	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	7			13.43	mmHg	1.98	5.23	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	50998	481
FHH/EurMcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	renin activity	female	87 days-120 days	5			12.61	ng/ml/h	1.89	4.23	radioimmunoassay				0				Moms and pups used in studies were fed Teklad	51002	481
GH/OmrMcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	renin activity	female	87 days-120 days	9			3.39	ng/ml/h	0.88	2.65	radioimmunoassay				0				Moms and pups used in studies were fed Teklad	51005	481
SS-Chr 9BN/Mcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	renin activity	female	87 days-120 days	14			2.21	ng/ml/h	0.35	1.3	radioimmunoassay				0				Moms and pups used in studies were fed Teklad	51010	481
FHH/EurMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	5			6.8	mmHg	2.91	6.51	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51019	481
SS-Chr 16BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	10			11.67	mmHg	1.81	5.73	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51024	481
LEW/Crl	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	7			0.07	beats/min	14.92	39.49	vascular fluid filled catheter				0					51041	481
F344/DuCrl	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	7			-20.57	beats/min	11.12	29.43	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51037	481
Hsd:SD	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	20			-1.58	mmHg	1.98	8.83	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	51038	481
SS-Chr 20BN/Mcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	glomerular filtration trait	male	87 days-120 days	10			1.2	ml/min	0.12	0.38	urine creatinine analysis				0				Moms and pups used in studies were fed Teklad	51061	481
Crl:CD(SD)	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	5			-2.18	mmHg	2.36	5.28	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51067	481
F344/DuCrl	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	9			117.34	mmHg	1.33	3.99	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51077	481
SS/JrHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	3			15.0	beats/min	17.09	29.6	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51070	481
SS-Chr 18BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	2			1.42	mmHg	1.42	2.0	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51083	481
SS-Chr 16BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	7			0.65	mmHg	2.07	5.48	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51084	481
SS-Chr 16BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	6			-4.01	beats/min	12.94	31.69	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51089	481
BN/NHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	3			-11.61	beats/min	15.08	26.12	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51098	481
SS-Chr 18BN/Mcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	9			407.56	beats/min	12.77	38.31	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51112	481
SS-Chr 16BN/Mcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	12			394.2	beats/min	10.18	35.26	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51117	481
SS/JrHsdMcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	12			432.92	beats/min	10.44	36.17	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51119	481
FHH/EurMcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	9			432.28	beats/min	13.8	41.4	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51122	481
Hsd:SD	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	20			-41.72	beats/min	7.75	34.65	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	51125	481
SS-Chr 20BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	15			-1.56	mmHg	2.17	8.42	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51132	481
SS-Chr 18BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	9			137.63	mmHg	3.75	11.25	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51139	481
SS-Chr 18BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	1			126.1	mmHg			vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51143	481
SHR/NCrl	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	8			139.16	mmHg	4.78	13.51	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51149	481
SS/JrHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	16			-16.62	beats/min	6.53	26.13	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51154	481
GH/OmrMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	9			-14.82	beats/min	11.3	33.9	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51156	481
F344/DuCrl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	7			14.0	mmHg	3.08	8.14	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51170	481
FHH/EurMcwi	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	blood creatinine amount	female	87 days-120 days	7			0.28	mg/dl	0.01	0.03	radioimmunoassay				0				Moms and pups used in studies were fed Dyets	51173	481
SS-Chr 16BN/Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	blood creatinine amount	male	87 days-120 days	7			0.35	mg/dl	0.01	0.02	radioimmunoassay				0				Moms and pups used in studies were fed Dyets	51177	481
GH/OmrMcwi	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	blood creatinine amount	male	87 days-120 days	8			0.31	mg/dl	0.01	0.02	radioimmunoassay				0				Moms and pups used in studies were fed Dyets	51182	481
FHH/EurMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	5			12.46	mmHg	3.39	7.58	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51183	481
GH/OmrMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	9			10.04	mmHg	3.19	9.56	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51186	481
SS-Chr 18BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	9			-34.31	beats/min	15.69	47.06	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51197	481
SS/JrHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	17			-27.92	beats/min	8.05	33.2	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51199	481
SS-Chr 16BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	10			-34.17	beats/min	7.73	24.44	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51203	481
SHR/NCrl	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	8			-60.76	beats/min	16.42	46.43	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51207	481
SS-Chr 9BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	6			-69.53	beats/min	11.28	27.64	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51225	481
SS/JrHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	15			10.55	beats/min	16.42	63.61	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51233	481
BN/NHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	8			-79.11	beats/min	25.39	71.8	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51230	481
SS-Chr 20BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	15			-21.84	beats/min	4.82	18.68	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51236	481
FHH/EurMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	7			-22.66	beats/min	17.34	45.89	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51239	481
SS-Chr 9BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	15			-15.78	beats/min	13.94	54.0	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51238	481
FHH/EurMcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	10			399.95	beats/min	7.51	23.75	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51253	481
Crl:CD(SD)	absolute change in heart rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	6			18.95	beats/min	7.34	17.98	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51260	481
BN/NHsdMcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	3			388.81	beats/min	6.13	10.62	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51255	481
BN/NHsdMcwi	urine sodium excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	urine sodium amount	male	87 days-120 days	3			0.95	mEq/d	0.15	0.26	flame atomic emission spectrometry				0				Moms and pups used in studies were fed Dyets	51275	481
SS/JrHsdMcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	18			393.77	beats/min	10.28	43.62	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51280	481
SS-Chr 20BN/Mcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	15			417.6	beats/min	6.66	25.79	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51281	481
GH/OmrMcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	9			381.9	beats/min	3.85	11.54	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51286	481
BN/NHsdMcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	8			408.04	beats/min	7.45	21.07	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51291	481
FHH/EurMcwi	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	blood creatinine amount	female	87 days-120 days	5			0.25	mg/dl	0.01	0.03	radioimmunoassay				0				Moms and pups used in studies were fed Teklad	51309	481
F344/DuCrl	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	7			-7.69	beats/min	11.36	30.07	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51331	481
F344/DuCrl	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	7			46.11	beats/min	18.25	48.29	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51333	481
GH/OmrMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	6			19.9	mmHg	4.12	10.08	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51339	481
FHH/EurMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	5			-5.36	beats/min	26.01	58.15	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51348	481
GH/OmrMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	9			-11.5	beats/min	12.54	37.62	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51351	481
SS-Chr 20BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	15			-27.23	beats/min	9.2	35.65	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51350	481
BN/NHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	8			10.88	beats/min	4.58	12.97	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51378	481
Crl:CD(SD)	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	4			109.0	mmHg	4.18	8.37	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51390	481
Crl:CD(SD)	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	4			103.26	mmHg	5.16	10.33	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51392	481
F344/DuCrl	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	1			101.06	mmHg			vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51393	481
LEW/Crl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	7			2.21	mmHg	3.42	9.04	vascular fluid filled catheter				0					51395	481
SS-Chr 16BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	7			36.49	mmHg	4.28	11.32	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51422	481
SS-Chr 18BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	1			45.65	mmHg			vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51423	481
SS-Chr 18BN/Mcwi	urine total protein excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	total urine protein amount	male	87 days-120 days	10			81.8	mg/d	23.56	74.51	automated urine analysis				0				Moms and pups used in studies were fed Dyets	51433	481
SHR/NCrl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	9			41.75	mmHg	2.35	7.05	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51426	481
SS-Chr 16BN/Mcwi	urine total protein excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	total urine protein amount	male	87 days-120 days	12			49.72	mg/d	6.98	24.18	automated urine analysis				0				Moms and pups used in studies were fed Dyets	51439	481
SS/JrHsdMcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	glomerular filtration trait	male	87 days-120 days	4			1.51	ml/min	0.23	0.45	urine creatinine analysis				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51448	481
SS-Chr 18BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	urine albumin amount	male	87 days-120 days	7			3.47	mg/d	0.73	1.92	automated urine analysis				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51454	481
SS-Chr 18BN/Mcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	glomerular filtration trait	female	87 days-120 days	2			0.73	ml/min	0.02	0.02	urine creatinine analysis				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51451	481
SS-Chr 20BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	urine albumin amount	female	87 days-120 days	19			6.82	mg/d	0.97	4.22	automated urine analysis				0				Moms and pups used in studies were fed Teklad	51467	481
SHR/NCrl	urine albumin excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	urine albumin amount	female	87 days-120 days	10			0.47	mg/d	0.04	0.12	automated urine analysis				0				Moms and pups used in studies were fed Teklad	51474	481
Hsd:SD	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	20			9.53	mmHg	1.49	6.66	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	51479	481
SS-Chr 16BN/Mcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	7			364.9	beats/min	8.85	23.41	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51486	481
SS-Chr 18BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	2			33.19	mmHg	3.65	5.16	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51491	481
SS-Chr 16BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	5			20.44	mmHg	5.29	11.82	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51490	481
FHH/EurMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	6			7.05	mmHg	1.68	4.12	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51496	481
SS-Chr 18BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	9			-37.54	beats/min	13.84	41.52	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51501	481
SS-Chr 16BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	7			-28.06	beats/min	17.7	46.83	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51504	481
SS/JrHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	12			-46.0	beats/min	14.52	50.29	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51509	481
SS-Chr 18BN/Mcwi	urine sodium excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	urine sodium amount	female	87 days-120 days	7			0.91	mEq/d	0.11	0.28	flame atomic emission spectrometry				0				Moms and pups used in studies were fed Teklad	51519	481
F344/DuCrl	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	7			-48.94	beats/min	12.72	33.65	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51530	481
FHH/EurMcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	glomerular filtration trait	female	87 days-120 days	7			1.45	ml/min	0.17	0.46	urine creatinine analysis				0				Moms and pups used in studies were fed Dyets	51542	481
SHR/NCrl	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	glomerular filtration trait	female	87 days-120 days	7			1.08	ml/min	0.08	0.2	urine creatinine analysis				0				Moms and pups used in studies were fed Dyets	51544	481
GH/OmrMcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	glomerular filtration trait	female	87 days-120 days	3			1.69	ml/min	0.06	0.1	urine creatinine analysis				0				Moms and pups used in studies were fed Dyets	51545	481
FHH/EurMcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	glomerular filtration trait	male	87 days-120 days	9			2.23	ml/min	0.08	0.25	urine creatinine analysis				0				Moms and pups used in studies were fed Dyets	51547	481
FHH/EurMcwi	urine total protein excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	total urine protein amount	male	87 days-120 days	8			59.56	mg/d	16.55	46.8	automated urine analysis				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51558	481
GH/OmrMcwi	urine albumin excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	urine albumin amount	female	87 days-120 days	7			1.34	mg/d	0.47	1.24	automated urine analysis				0				Moms and pups used in studies were fed Dyets	51564	481
SS-Chr 16BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	urine albumin amount	male	87 days-120 days	12			22.08	mg/d	3.69	12.78	automated urine analysis				0				Moms and pups used in studies were fed Dyets	51565	481
SHR/NCrl	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	8			328.06	beats/min	5.66	16.02	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51582	481
SHR/NCrl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	9			2.21	mmHg	3.87	11.6	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51596	481
Hsd:SD	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	renin activity	male	87 days-120 days	5			1.65	ng/ml/h	0.44	0.98	radioimmunoassay				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	51620	481
FHH/EurMcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	8			122.1	mmHg	1.91	5.4	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51627	481
F344/DuCrl	urine sodium excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	urine sodium amount	male	87 days-120 days	8			7.87	mEq/d	1.47	4.17	flame atomic emission spectrometry				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51640	481
FHH/EurMcwi	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	blood creatinine amount	female	87 days-120 days	5			0.23	mg/dl	0.01	0.02	radioimmunoassay				0				Moms and pups used in studies were fed Teklad	51643	481
SS-Chr 18BN/Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	blood creatinine amount	female	87 days-120 days	5			0.26	mg/dl	0.01	0.02	radioimmunoassay				0				Moms and pups used in studies were fed Teklad	51647	481
SS-Chr 9BN/Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	blood creatinine amount	female	87 days-120 days	14			0.26	mg/dl	0.01	0.03	radioimmunoassay				0				Moms and pups used in studies were fed Teklad	51651	481
SHR/NCrl	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	blood creatinine amount	female	87 days-120 days	6			0.26	mg/dl	0.0	0.01	radioimmunoassay				0				Moms and pups used in studies were fed Teklad	51652	481
BN/NHsdMcwi	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	blood creatinine amount	male	87 days-120 days	3			0.28	mg/dl	0.03	0.05	radioimmunoassay				0				Moms and pups used in studies were fed Teklad	51655	481
FHH/EurMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	2			25.88	mmHg	1.67	2.36	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51660	481
SS-Chr 20BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	15			36.48	mmHg	2.7	10.45	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51662	481
Crl:CD(SD)	urine albumin excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	urine albumin amount	male	87 days-120 days	9			0.59	mg/d	0.08	0.25	automated urine analysis				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51669	481
FHH/EurMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	7			30.91	mmHg	4.23	11.18	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51665	481
BN/NHsdMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	4			31.19	mmHg	2.1	4.2	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51667	481
FHH/EurMcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	7			377.14	beats/min	16.4	43.39	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50329	481
SS-Chr 18BN/Mcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	6			451.67	beats/min	18.13	44.41	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50327	481
Hsd:SD	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	20			124.48	mmHg	1.9	8.48	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	50333	481
Hsd:SD	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	15			114.94	mmHg	1.51	5.86	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	50334	481
SS-Chr 18BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	2			-57.41	beats/min	0.99	1.4	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50338	481
SS-Chr 16BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	7			-48.51	beats/min	15.93	42.16	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50339	481
SS-Chr 16BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	7			-45.24	beats/min	26.63	70.44	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50347	481
SS-Chr 9BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	9			-47.44	beats/min	16.66	49.97	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50353	481
BN/NHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	4			-45.27	beats/min	22.01	44.02	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50363	481
SHR/NCrl	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	6			-12.88	beats/min	7.63	18.69	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50364	481
SS-Chr 18BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	6			6.33	mmHg	2.64	6.46	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50369	481
BN/NHsdMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	8			3.61	mmHg	1.8	5.09	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50378	481
FHH/EurMcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	renin activity	female	87 days-120 days	6			11.87	ng/ml/h	0.85	2.08	radioimmunoassay				0				Moms and pups used in studies were fed Dyets	50389	481
SHR/NCrl	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	renin activity	female	87 days-120 days	7			10.95	ng/ml/h	1.24	3.28	radioimmunoassay				0				Moms and pups used in studies were fed Dyets	50391	481
FHH/EurMcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	renin activity	male	87 days-120 days	9			11.85	ng/ml/h	0.69	2.08	radioimmunoassay				0				Moms and pups used in studies were fed Dyets	50394	481
LEW/Crl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	5			4.13	mmHg	3.85	8.62	vascular fluid filled catheter				0					50406	481
WKY/NCrl	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	blood creatinine amount	male	87 days-120 days	9			0.4	mg/dl	0.02	0.06	radioimmunoassay				0					50409	481
WKY/NCrl	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	blood creatinine amount	female	87 days-120 days	5			0.42	mg/dl	0.03	0.07	radioimmunoassay				0					50412	481
BN/NHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	8			-8.48	beats/min	15.29	43.23	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	50429	481
SS-Chr 16BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	5			-0.61	mmHg	2.07	4.64	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50432	481
SS-Chr 16BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	7			-0.2	mmHg	4.63	12.24	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50434	481
WKY/NCrl	urine sodium excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	urine sodium amount	female	87 days-120 days	8			1.16	mEq/d	0.2	0.56	flame atomic emission spectrometry				0					50439	481
FHH/EurMcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	6			410.27	beats/min	18.86	46.2	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50446	481
SS/JrHsdMcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	renin activity	male	87 days-120 days	14			0.93	ng/ml/h	0.15	0.56	radioimmunoassay				0				Moms and pups used in studies were fed Dyets	50456	481
SHR/NCrl	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	renin activity	male	87 days-120 days	7			0.83	ng/ml/h	0.23	0.6	radioimmunoassay				0				Moms and pups used in studies were fed Dyets	50464	481
FHH/EurMcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	renin activity	male	87 days-120 days	8			9.0	ng/ml/h	0.76	2.15	radioimmunoassay				0				Moms and pups used in studies were fed Dyets	50462	481
GH/OmrMcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	9			400.42	beats/min	13.3	39.9	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50473	481
SHR/NCrl	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	4			349.08	beats/min	20.02	40.03	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50476	481
FHH/EurMcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	6			358.13	beats/min	16.04	39.3	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50481	481
SHR/NCrl	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	9			385.51	beats/min	15.45	46.36	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50479	481
Hsd:SD	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	19			4.09	mmHg	1.31	5.69	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	50498	481
Hsd:SD	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	15			8.67	mmHg	1.66	6.43	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	50499	481
SS/Jr	both kidneys wet weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	kidney mass	male	98 days	16			12.1	g/kg	0.3	1.2	post excision weight measurement		0		0					64772	226
SS.LEW-(D18Chm41-D18Rat92)/Ayd	both kidneys wet weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	kidney mass	male	98 days	5			10.1	g/kg	0.4	0.89	post excision weight measurement		0		0					64775	226
SS.LEW-(D8Rat56-D8Rat51)/Ayd	both kidneys wet weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	kidney mass	male	98 days	9			11.1	g/kg	0.4	1.2	post excision weight measurement		0		0					64788	226
SS.MNS-(D2Wox27-Adh1)/Ayd	both kidneys wet weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	kidney mass	male	98 days	5			10.3	g/kg	0.2	0.45	post excision weight measurement		0		0					64796	226
SS.LEW-(D2Rat18-D2Chm277)/Ayd	both kidneys wet weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	kidney mass	male	98 days	6			12.2	g/kg	0.3	0.73	post excision weight measurement		0		0					64800	226
SS.MNS-(D2Chm25-Fgg)/Ayd	heart left ventricle weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	heart left ventricle mass	male	98 days	9			2.94	mg/g	0.08	0.24	post excision weight measurement		0		0					64950	226
SS.MNS-(D2Chm51-D2Rat341)/Ayd	heart right ventricle weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	heart right ventricle mass	male	98 days	8			0.62	mg/g	0.02	0.06	post excision weight measurement		0		0					64955	226
SS.LEW-(D2Rat199-D2Mco17)/Ayd	heart right ventricle weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	heart right ventricle mass	male	98 days	8			0.7	mg/g	0.03	0.08	post excision weight measurement		0		0					64963	226
SS.BN-(D13Rat151-D13Rat197)/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (for 18 days)	Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12.	urine albumin amount	male	84 days-88 days	12			49.3	mg/d	3.7	12.82	urine analysis		86400		0					65249	15
SS/Jr	body weight	controlled sodium content diet (4 %) (for 14 days)	Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8.	body mass	male	53 days-67 days	10			297.0	g	5.0	15.81	body weighing method		0		0					66107	691
SS.SR-(D3Arb14-D3Mco36)/Mco	heart left ventricle relative wall thickness	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 29 days) then controlled sodium content diet (4 %) (between 40 and 41 days)	Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.	heart left ventricle wall thickness	male	109 days-112 days	7	(SWT+PWT)/LVDd		67.0	%	9.0	23.81	transthoracic echocardiography		0		0					65759	283
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco	heart left ventricle relative wall thickness	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 29 days) then controlled sodium content diet (4 %) (between 40 and 41 days)	Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.	heart left ventricle wall thickness	male	109 days-112 days	6	(SWT+PWT)/LVDd		85.0	%	3.0	7.35	transthoracic echocardiography		0		0					65760	283
SS.SR-Inha/Jr	heart wet weight	controlled sodium content diet (2 %) (for 24 days)	Rapp JP, et al., Genomics 1998 Jul 15;51(2):191-6	heart mass	male	62 days	20			1.25	g	0.01	0.06	post excision weight measurement		0		0					65835	633
SS/Jr	systolic blood pressure	controlled sodium content diet (4 %) (for 14 days)	Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8.	arterial blood pressure trait	male	67 days	10			218.0	mmHg	7.8	24.67	tail cuff plethysmography		0		0					66117	691
SS-Chr 13BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (for 18 days)	Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12.	urine albumin amount	female	84 days-88 days	12			15.9	mg/d	2.1	7.27	urine analysis		86400		0					65203	15
SS.BN-(D13Rat7-D13Rat60)/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (for 18 days)	Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12.	urine albumin amount	male	84 days-88 days	12			69.4	mg/d	12.6	43.65	urine analysis		86400		0					65205	15
SS.BN-(D13Rat20-D13Rat127)/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (for 18 days)	Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12.	urine albumin amount	female	84 days-88 days	12			21.2	mg/d	4.9	16.97	urine analysis		86400		0					65216	15
SS.BN-(D13Rat127-D13Rat77)/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (for 18 days)	Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12.	urine albumin amount	male	84 days-88 days	12			66.5	mg/d	7.3	25.29	urine analysis		86400		0					65230	15
SS.BN-(D13Rat57-D13Rat192)/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (for 18 days)	Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12.	urine albumin amount	male	84 days-88 days	12			62.8	mg/d	3.9	13.51	urine analysis		86400		0					65246	15
SS/NEisSlc	plasma aldosterone level	controlled sodium content diet (8 %)	Kitada K, et al., PLoS One. 2012;7(7):e41896. Epub 2012 Jul 24.	blood aldosterone amount	male	42 days	4			139.3	pg/ml	22.8	45.6	radioimmunoassay		0.0		0					67280	736
SS.BN-(D13Rat7-D13Rat60)/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 16 and 19 days)	Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12.	arterial blood pressure trait	female	86 days-89 days	12			148.0	mmHg	3.7	12.82	vascular fluid filled catheter	left femoral artery	14400		0		on 3 consecutive days			5395	15
SS/Jr	body weight	controlled sodium content diet (2 %) (between 24 and 27 days)	Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23	body mass	not specified	64 days-71 days	46			302.0	g	1.8	12.21	body weighing method		0		0				4 rats per cage, 2 SR/Jr 2 LEW/NCrl	64713	222
SS.LEW-(D10Mit10-D10Mgh1)/Jr	body weight	controlled sodium content diet (2 %) (between 24 and 27 days)	Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23	body mass	not specified	64 days-71 days	20			292.0	g	2.1	9.39	body weighing method		0		0				4 rats per cage, 2 SR/Jr 2 LEW/NCrl	64725	222
SS/Jr	body weight	controlled sodium content diet (2 %) (between 24 and 27 days)	Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23	body mass	not specified	64 days-71 days	40			304.0	g	1.6	10.12	body weighing method		0		0				4 rats per cage, 2 SR/Jr 2 LEW/NCrl	64716	222
SS/Jr	body weight	controlled sodium content diet (2 %) (between 24 and 27 days)	Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23	body mass	not specified	64 days-71 days	20			290.0	g	1.9	8.5	body weighing method		0		0				4 rats per cage, 2 SR/Jr 2 LEW/NCrl	64718	222
SS.SR-(D3Arb14-D3Mco36)/Mco	heart left ventricle fractional shortening	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 29 days) then controlled sodium content diet (4 %) (between 40 and 41 days)	Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.	heart left ventricle end-diastolic diameter	male	109 days-112 days	7			54.0	%	3.0	7.94	transthoracic echocardiography		0		0					65750	283
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco	velocity of circumferential fiber shortening	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 29 days) then controlled sodium content diet (4 %) (between 40 and 41 days)	Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.	heart left ventricle end-diastolic diameter	male	109 days-112 days	7			848.0	%/s	50.0	132.29	transthoracic echocardiography		0		0					65755	283
SS/Jr	velocity of circumferential fiber shortening	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 29 days) then controlled sodium content diet (4 %) (between 40 and 41 days)	Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.	heart left ventricle end-diastolic diameter	male	109 days-112 days	6			548.0	%/s	59.0	144.52	transthoracic echocardiography		0		0					65753	283
SS/JrSeac	body weight	controlled sodium content diet (8 %) (for 35 days)	Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1.	body mass	not specified	126 days	5			273.0	g	6.26	14.0	body weighing method		0.0		0					67256	733
SS/HsdMcwiCrl	absolute change in mean arterial blood pressure	controlled sodium content diet (0.15 %) (for 21 days) then dihydrocapsaicin (30 ug/kg) and pentobarbital (50 mg/kg)	Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1.	arterial blood pressure trait	male	35 days-56 days	0			-28.0	mmHg	4.0		tail cuff plethysmography		0.0		0				DR strain is from Charles River Laboratory, Wilmington, MA	67262	731
SS/JrHsdMcwi	kidney glomerulus diameter	controlled sodium content diet (0.4 %) (for 35 days)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	kidney glomerulus size trait	female	97 days-101 days	16			117.0	um	3.8	15.2	ex vivo light microscopy		0.0		0		plasma creatinine analysis	glomerular diameter		67286	151
BN/NHsdMcwi	absolute change in mean arterial blood pressure	furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then angiotensin II (200 ng/kg/min) (for 0.1 hours)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	arterial blood pressure trait	female	101 days-103 days	20		serial mean	27.0	mmHg	2.0	8.94	vascular indwelling catheter method	left femoral artery	0.0		0					67299	151
SS/JrHsdMcwi	ratio of change in renal blood flow rate to kidney weight	controlled sodium content diet (0.4 %) (for 16 hours) then norepinephrine (3 ug/kg/min) (for 0.1 hours)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	renal blood flow trait	female	97 days-101 days	13			-2.4	ml/min/g	0.6	2.16	electromagnetic flowmetry		0.0		0		electromagnetic flowmetry			67308	151
BN/NHsdMcwi	ratio of change in renal blood flow rate to kidney weight	controlled sodium content diet (0.4 %) (for 16 hours) then angiotensin II (200 ng/kg/min) (for 0.1 hours)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	renal blood flow trait	female	97 days-101 days	21			-1.4	ml/min/g	0.3	1.37	electromagnetic flowmetry		0.0		0		electromagnetic flowmetry	change in renal blood flow rate		67305	151
SS/Jr	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	arterial blood pressure trait	not specified	65 days-70 days	20			222.0	mmHg	5.01	22.41	tail cuff plethysmography		0.0		0					67311	749
SS.SR-(D13Mit9-D13Mit1)/Jr	systolic blood pressure	controlled sodium content diet (8 %) (between 62 and 69 days) then controlled exposure to darkness	St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7	arterial blood pressure trait	female	56 days-63 days	8		serial mean	122.0	mmHg	2.0	5.66	intra-aortic abdominal radiotelemetry		604800.0		0		5 s every 5 min nightly for a week			11707	119
SS/Jr	heart wet weight	controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (for 28 days)	Cicila GT, et al., Mamm Genome 1999 Feb;10(2):112-6.	heart mass	male	65 days	20			1.29	g	0.02	0.08	post excision weight measurement				0					11777	145
SS/Jr	heart wet weight	controlled sodium content diet (1 %) (for 30 days) then controlled sodium content diet (0.2 %) (for 40 days)	Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902.	heart mass	male	100 days	21			1.28	g	0.02	0.11	post excision weight measurement				0					11783	146
SS.SR-(Cyp11b1)/Jr	body weight	controlled sodium content diet (1 %) (for 30 days) then controlled sodium content diet (0.2 %) (for 40 days)	Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902.	body mass	male	100 days	16			336.7	g	6.7	26.8	body weighing method				0					11786	146
SS/Jr	systolic blood pressure	controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (for 42 days)	Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902.	arterial blood pressure trait	male	79 days	20		serial mean	231.4	mmHg	7.2	32.2	tail cuff plethysmography				0					11789	146
SS.SR-(Cyp11b1)/Jr	systolic blood pressure	controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (for 42 days)	Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902.	arterial blood pressure trait	male	79 days	20		serial mean	198.1	mmHg	5.7	25.49	tail cuff plethysmography				0					11790	146
SS/Jr	body weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)	Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.	body mass	male	68 days-70 days	20			298.2	g	4.2	18.78	body weighing method				0					11799	147
SS/Jr	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)	Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.	arterial blood pressure trait	male	68 days-70 days	20		serial mean	230.6	mmHg	4.7	21.02	tail cuff plethysmography				0			average of 12 readings from 4 daily sessions		11807	147
SS.SR-(D7Uia1-D7Mco7)/Jr	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)	Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.	arterial blood pressure trait	male	68 days-70 days	20		serial mean	205.0	mmHg	1.8	8.05	tail cuff plethysmography				0			average of 12 readings from 4 daily sessions		11814	147
SS/Jr	body weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)	Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.	body mass	male	68 days-70 days	20			289.8	g	3.2	14.31	body weighing method				0					11817	147
SS/Jr	body weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)	Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.	body mass	male	68 days-70 days	20			297.7	g	2.5	11.18	body weighing method				0					11823	147
SS.SR-(D7Mco7-D7Wox19)/Jr	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)	Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.	arterial blood pressure trait	male	68 days-70 days	20		serial mean	209.0	mmHg	2.2	9.84	tail cuff plethysmography				0			average of 12 readings from 4 daily sessions		11820	147
SS.MNS-(D10Mco14-D10Mit11)/Jr	systolic blood pressure	controlled sodium content diet (2 %) (between 25 and 28 days)	Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35.	arterial blood pressure trait	not specified	64 days-68 days	20		serial mean	175.0	mmHg	1.7	7.6	tail cuff plethysmography				0			average of 12 readings from 4 daily sessions		11832	148
SS.SR-(D7Rat16-D7Rat176)/Jr	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)	Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.	arterial blood pressure trait	male	68 days-70 days	19		serial mean	223.7	mmHg	4.0	17.44	tail cuff plethysmography				0			average of 12 readings from 4 daily sessions		11826	147
SS.MNS-(Aldoc-D10Mco1)/Jr	systolic blood pressure	controlled sodium content diet (2 %) (between 25 and 28 days)	Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35.	arterial blood pressure trait	not specified	64 days-68 days	38		serial mean	210.0	mmHg	2.7	16.64	tail cuff plethysmography				0			average of 12 readings from 4 daily sessions		11842	148
SS/Jr	heart weight to body weight ratio	controlled sodium content diet (2 %) (between 25 and 28 days)	Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35.	heart mass	not specified	64 days-68 days	20			3.95	g/kg	0.05	0.22	post excision weight measurement				0					11839	148
SS.WKY-(D2N35-Mme),MNS-(D10Mit11-D10M11Mit119)/Mco	systolic blood pressure	controlled sodium content diet (0.2 %) (between 15 and 18 days) then controlled sodium content diet (2 %) (between 25 and 28 days)	Rapp JP, et al., J Clin Invest 1998 Apr 15;101(8):1591-5.	arterial blood pressure trait	male	70 days-76 days	24		serial mean	170.0	mmHg	1.4	6.86	tail cuff plethysmography				0					11848	150
SS/JrHsdMcwi	mean arterial blood pressure	controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	arterial blood pressure trait	female	89 days-92 days	21		serial mean	174.0	mmHg	6.0	27.5	vascular indwelling catheter method	left femoral artery			0		3 hrs (during inactive phase) 3 consecutive days, and 4 extra hrs (during active phase) next day			11854	151
SS.MNS-(D2Rat183-D2Chm113)/Ayd	mean arterial blood pressure	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	arterial blood pressure trait	male	68 days-98 days	8			145.0	mmHg	4.0	11.31	radiotelemetry		30		0					11934	226
SS.LEW-(D3Got33-D3Chm68)/Ayd	mean arterial blood pressure	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	arterial blood pressure trait	male	68 days-98 days	10			156.0	mmHg	6.0	18.97	radiotelemetry		30		0					11943	226
SS.LEW-(D10Chm10-D10Rat11)/Ayd	mean arterial blood pressure	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	arterial blood pressure trait	male	68 days-98 days	7			150.0	mmHg	2.0	5.29	radiotelemetry		30		0					11956	226
SS.LEW-(D17Rat65-D17Chm2)/Ayd	mean arterial blood pressure	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	arterial blood pressure trait	male	68 days-98 days	5			171.0	mmHg	8.0	17.89	radiotelemetry		30		0					11963	226
SS/Jr	heart weight to body weight ratio	controlled sodium content diet (2 %) (between 24 and 27 days)	Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85	heart mass	male	64 days-69 days	20			4.39	g/kg	0.05	0.24	post excision weight measurement				0					11987	221
SS/Jr	heart weight to body weight ratio	controlled sodium content diet (2 %) (between 24 and 27 days)	Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85	heart mass	male	64 days-69 days	20			4.09	g/kg	0.03	0.14	post excision weight measurement				0					11994	221
SS/JrHsdMcwi	diastolic blood pressure	controlled sodium content diet (0.1 %) (for 28 days) then controlled sodium content diet (8 %) (for 31 days) and controlled exposure to ambient light (for 12 hours)	Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15.	arterial blood pressure trait	male	91 days-94 days	35		continuous mean	167.0	mmHg	4.0	23.66	vascular indwelling catheter method	femoral artery	259200.0		0		3 h per day			12002	229
SS.LEW-(D10Mco38-D10Mgh1)/Jr	heart weight to body weight ratio	controlled sodium content diet (2 %) (between 24 and 27 days)	Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85	heart mass	male	64 days-69 days	20			3.89	g/kg	0.03	0.15	post excision weight measurement				0					12008	221
BN/NHsdMcwi	systolic blood pressure	controlled sodium content diet (0.1 %) (for 28 days) then controlled sodium content diet (8 %) (for 31 days) and controlled exposure to ambient light (for 12 hours)	Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15.	arterial blood pressure trait	male	91 days-94 days	42		continuous mean	127.0	mmHg	3.0	19.44	vascular indwelling catheter method	femoral artery	259200.0		0		3 h per day			12006	229
SS/Jr	heart wet weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Saad Y, et al., Hypertension. 2007	heart mass	male	64 days-66 days	0			1.32	g	0.01		post excision weight measurement				0					12011	205
SS.LEW-(D2Rat18-D2Chm277)/Ayd	body weight	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	body mass	male	98 days	6			311.0	g	20.0	48.99	body weighing method		0		0					12014	226
SS.LEW-(D10Mco84-D10Rat58)/Mco	heart wet weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Saad Y, et al., Hypertension. 2007	heart mass	male	64 days-66 days	0			1.45	g	0.01		post excision weight measurement				0					12023	205
SS.MNS-(D2Wox27-Adh1)/Ayd	body weight	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	body mass	male	98 days	5			352.0	g	15.0	33.54	body weighing method		0		0					12032	226
SS.LEW-(D3Rat52-D3Rat130)/Ayd	body weight	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	body mass	male	98 days	7			390.0	g	6.0	15.87	body weighing method		0		0					12037	226
SS.MNS-(D10Rat13-D10Rat12)/Jr	heart weight to body weight ratio	controlled sodium content diet (2 %) (between 24 and 27 days)	Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85	heart mass	male	64 days-69 days	20			4.19	g/kg	0.05	0.22	post excision weight measurement				0					12044	221
SS.MNS-(D10Mco62-D10Mit1)/Jr	heart weight to body weight ratio	controlled sodium content diet (2 %) (between 24 and 27 days)	Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85	heart mass	male	64 days-69 days	20			3.82	g/kg	0.03	0.12	post excision weight measurement				0					12047	221
SS.LEW-(D10Mco84-D10Mco143)/Mco	heart weight to body weight ratio	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Saad Y, et al., Hypertension. 2007	heart mass	male	64 days-66 days	0			4.06	g/kg	0.06		post excision weight measurement				0					12053	205
SS.LEW-(D10Chm10-D10Rat11)/Ayd	body weight	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	body mass	male	98 days	7			375.0	g	5.0	13.23	body weighing method		0		0					12061	226
SS.LEW-(D10Chm128-D10Chm169)/Ayd	body weight	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	body mass	male	98 days	8			369.0	g	6.0	16.97	body weighing method		0		0					12063	226
SS.LEW-(D10Mco84-D10Mco129)/Mco	heart weight to body weight ratio	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Saad Y, et al., Hypertension. 2007	heart mass	male	64 days-66 days	0			4.32	g/kg	0.01		post excision weight measurement				0					12056	205
SS.LEW-(D17Chm14-D17Rat181)/Ayd	body weight	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	body mass	male	98 days	5			377.0	g	9.0	20.12	body weighing method		0		0					12069	226
LEW	body weight	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	body mass	male	98 days	6			372.0	g	9.0	22.05	body weighing method		0		0					12080	226
SS.WKY-(D2N35-Mme)/Mco	systolic blood pressure	controlled sodium content diet (2 %) (between 25 and 28 days)	Deng AY, et al., Hypertension 1997 Aug;30(2 Pt 1):199-202	arterial blood pressure trait	male	65 days-68 days	27			161.9	mmHg	2.45	12.73	tail cuff photoplethysmography	tail			0		average of 4 days, 3 to 4 consistent readings each day, IITC			12105	231
SS.LEW-(D8Rat56-D8Rat51)/Ayd	heart weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	heart mass	male	98 days	9			4.7	g/kg	0.4	1.2	post excision weight measurement		0		0					12107	226
SS.LEW-(D17Rat65-D17Chm2)/Ayd	heart weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	heart mass	male	98 days	5			3.6	g/kg	0.2	0.45	post excision weight measurement		0		0					12118	226
SS.LEW-(D16Got3-D16Rat112)/Ayd	heart weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	heart mass	male	98 days	9			3.43	g/kg	0.06	0.18	post excision weight measurement		0		0					12116	226
SS/Jr	heart weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	heart mass	male	98 days	16			4.1	g/kg	0.1	0.4	post excision weight measurement		0		0					12124	226
SS.LEW-(D17Chm9-D17Rat97)/Ayd	heart weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	heart mass	male	98 days	10			3.9	g/kg	0.1	0.32	post excision weight measurement		0		0					12119	226
SS.MNS-(D10Mco30-D10Got112)/Mco	systolic blood pressure	controlled sodium content diet (2 %) (for 24 days)	Saad Y, et al., Mamm Genome. 2008 Jan 4	arterial blood pressure trait	male	64 days-68 days	20			190.0	mmHg	2.55	11.4	tail cuff plethysmography	tail	345600		0		warm up to 28 C	Average of 3-4 consistent measurements taken each day over 4 consecutive days		12135	232
SS.MNS-(D10Mco30-D10Got91)/1Mco	systolic blood pressure	controlled sodium content diet (2 %) (for 24 days)	Saad Y, et al., Mamm Genome. 2008 Jan 4	arterial blood pressure trait	male	64 days-68 days	20			206.0	mmHg	5.06	22.63	tail cuff plethysmography	tail	345600		0		warm up to 28 C	Average of 3-4 consistent measurements taken each day over 4 consecutive days		12138	232
SS/Jr	body weight	controlled sodium content diet (2 %) (for 24 days)	Saad Y, et al., Mamm Genome. 2008 Jan 4	body mass	male	64 days-68 days	20			312.0	g	3.22	14.4	body weighing method		0		0					12143	232
SS.MNS-(D10Mco30-D10Got91)/3Mco	systolic blood pressure	controlled sodium content diet (2 %) (for 24 days)	Saad Y, et al., Mamm Genome. 2008 Jan 4	arterial blood pressure trait	male	64 days-68 days	20			193.0	mmHg	3.5	15.65	tail cuff plethysmography	tail	345600.0		0		warm up to 28 C	Average of 3-4 consistent measurements taken each day over 4 consecutive days		12140	232
SR/Jr	systolic blood pressure	controlled sodium content diet (0.2 %) (for 112 days)	Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23	arterial blood pressure trait	male	147 days	10		serial mean	132.0	mmHg	3.1	9.8	tail cuff plethysmography	tail	0		0					12165	222
SR/Jr	systolic blood pressure	controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 56 days)	Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23	arterial blood pressure trait	male	91 days	10		serial mean	159.0	mmHg	2.0	6.32	tail cuff plethysmography	tail	0		0					12168	222
SR/Jr	systolic blood pressure	controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 28 days)	Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23	arterial blood pressure trait	male	63 days	10		serial mean	150.0	mmHg	3.5	11.07	tail cuff plethysmography	tail	0		0					12167	222
SR/Jr	systolic blood pressure	controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 168 days)	Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23	arterial blood pressure trait	male	203 days	10		serial mean	156.0	mmHg	4.0	12.65	tail cuff plethysmography	tail	0		0					12170	222
SR/Jr	body weight	controlled sodium content diet (0.2 %) (for 28 days)	Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23	body mass	male	63 days	10			238.0	g	4.7	14.86	body weighing method		0		0				4 rats per cage, 2 SR/Jr 2 LEW/NCrl	12180	222
SR/Jr	body weight	controlled sodium content diet (0.2 %) (for 112 days)	Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23	body mass	male	147 days	10			379.0	g	5.7	18.02	body weighing method		0		0				4 rats per cage, 2 SR/Jr 2 LEW/NCrl	12182	222
LEW/NCrl	body weight	controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 28 days)	Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23	body mass	male	63 days	8			286.0	g	4.4	12.45	body weighing method		0		0				4 rats per cage, 2 SR/Jr 2 LEW/NCrl	12194	222
SS.MNS-(D10Mco62-D10Mco30)/Mco	heart wet weight	controlled sodium content diet (2 %) (for 24 days)	Saad Y, et al., Mamm Genome. 2008 Jan 4	heart mass	male	64 days-68 days	20			1.37	g	0.03	0.13	post excision weight measurement		0		0					12205	232
SS.MNS-(D10Mco30-D10Got91)/3Mco	heart weight to body weight ratio	controlled sodium content diet (2 %) (for 24 days)	Saad Y, et al., Mamm Genome. 2008 Jan 4	heart mass	male	64 days-68 days	20			3.77	g/kg	0.02	0.09	post excision weight measurement		0		0					12215	232
SS.SR-(D3Mco36-D3Got166)/Jr	heart wet weight	controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)	Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.	heart mass	male	70 days-72 days	40			1.12	g	0.02	0.09	post excision weight measurement				0					12255	237
SS/Jr	heart wet weight	controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)	Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.	heart mass	male	70 days-72 days	40			1.15	g	0.01	0.06	post excision weight measurement				0					12279	237
SS.SR-(D3Mco39-D3Got130)/Jr	heart wet weight	controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)	Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.	heart mass	male	70 days-72 days	39			1.08	g	0.01	0.07	post excision weight measurement				0					12277	237
SS/Jr	both kidneys wet weight	controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)	Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.	kidney mass	male	70 days-72 days	20			2.9	g	0.05	0.23	post excision weight measurement				0					12316	237
SS.SHR-(D8Uia1-D8Rat90)/Mco	body weight	controlled sodium content diet (0.3 %)	Packard M, et al., Am J Physiol Renal Physiol. 2009 Apr;296(4):F839-46. Epub 2009 Jan 28.	body mass	male	84 days	12			366.0	g	4.3	14.9	body weighing method		0		0					12332	246
SS.SHR-(D13Rat63-D13Mit1)/Mco	both kidneys wet weight	controlled sodium content diet (0.3 %)	Packard M, et al., Am J Physiol Renal Physiol. 2009 Apr;296(4):F839-46. Epub 2009 Jan 28.	kidney mass	male	84 days	12			2.79	g	0.05	0.18	post excision weight measurement		0		0					12340	246
SS/Jr	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Saad Y, et al., Hypertension. 2007	arterial blood pressure trait	male	64 days-66 days	0			221.0	mmHg	3.95		tail cuff plethysmography				0		warm up to 28 C	Average of 3-4 consistent measurements taken each day over 4 consecutive days		11913	205
SS/Jr	body weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)	Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.	body mass	male	68 days-70 days	20			303.0	g	2.86	12.79	whole body digital scale		0		0					12688	282
SS/Jr	heart weight to body weight ratio	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)	Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.	heart mass	male	68 days-70 days	20			4.26	g/kg	0.07	0.3	digital scale post excision weight measurement		0		0					12707	282
SS.LEW-(D10Rat24-Igfbp4)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 50 days)	Chauvet C, et al., J Hypertens. 2008 May;26(5):893-901.	arterial blood pressure trait	male	66 days-78 days	7		serial mean	177.0	mmHg	6.0	15.87	intra-aortic abdominal radiotelemetry	abdominal aorta	1036800		0		telemetry probe model PA-D70, Data Sciences, St. Paul, MN	average of 24 hour averages over 12 days		12739	304
SS.LEW-(D10Mco15-D10Mgh1)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 50 days)	Chauvet C, et al., J Hypertens. 2008 May;26(5):893-901.	arterial blood pressure trait	male	66 days-78 days	6		serial mean	180.0	mmHg	6.0	14.7	intra-aortic abdominal radiotelemetry	abdominal aorta	1036800		0		telemetry probe model PA-D70, Data Sciences, St. Paul, MN	average of 24 hour averages over 12 days		12742	304
SS.LEW-(D10Chm10-D10Chm14)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 50 days)	Chauvet C, et al., J Hypertens. 2008 May;26(5):893-901.	arterial blood pressure trait	male	66 days-78 days	5		serial mean	168.0	mmHg	6.0	13.42	intra-aortic abdominal radiotelemetry	abdominal aorta	1036800		0		telemetry probe model PA-D70, Data Sciences, St. Paul, MN	average of 24 hour averages over 12 days		12743	304
SS/Jr	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.	arterial blood pressure trait	male	64 days-66 days	20			195.0	mmHg	3.27	14.62	tail cuff plethysmography		4		0		semi- automatic equipment from IITC, Woodland Hills, CA	average of 2-3 readings/day over 4 days		12807	313
SS.LEW-(D1Mco36-D1Rat131)/2Mco	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.	arterial blood pressure trait	male	64 days-66 days	20			170.0	mmHg	2.33	10.42	tail cuff plethysmography		4		0		semi- automatic equipment from IITC, Woodland Hills, CA	average of 2-3 readings/day over 4 days		12818	313
SS.LEW-(D1Mco36-D1Mco77)/Mco	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.	arterial blood pressure trait	male	64 days-66 days	20			184.0	mmHg	3.07	13.73	tail cuff plethysmography		4		0		semi- automatic equipment from IITC, Woodland Hills, CA	average of 2-3 readings/day over 4 days		12819	313
SS.LEW-(D1Mco36-D1Rat131)/1Mco	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.	arterial blood pressure trait	male	64 days-66 days	20			178.0	mmHg	2.22	9.93	tail cuff plethysmography		4		0		semi- automatic equipment from IITC, Woodland Hills, CA	average of 2-3 readings/day over 4 days		12817	313
SS.SHR-(D9Mco72-D9Mco93)/Mco	systolic blood pressure	controlled sodium content diet (2 %) (between 35 and 37 days)	Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.	arterial blood pressure trait	male	75 days-79 days	5		serial mean	146.0	mmHg	1.44	3.22	intra-aortic abdominal radiotelemetry	lower abdominal aorta	172800		0		C-40 transmitter (Data Sciences International, St. Paul, MN)	average of 12 4-hour averages over 48 hours using 5 or 6 rats		13030	305
SS.SHR-(D9Mco74-D9Rat64)/Mco	diastolic blood pressure	controlled sodium content diet (2 %) (between 35 and 37 days)	Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.	arterial blood pressure trait	male	75 days-79 days	5		serial mean	108.0	mmHg	1.32	2.95	intra-aortic abdominal radiotelemetry	lower abdominal aorta	172800		0		C-40 transmitter (Data Sciences International, St. Paul, MN)	average of 12 4-hour averages over 48 hours using 5 or 6 rats		13033	305
SS/Jr	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.	arterial blood pressure trait	male	64 days-70 days	44		serial mean	190.0	mmHg	1.61	10.68	tail cuff photoplethysmography	tail	345600		0			average of 4 daily averages of 3-4 measurements/day		13116	282
SS/Jr	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)	Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.	arterial blood pressure trait	male	64 days-70 days	30		serial mean	206.0	mmHg	2.23	12.21	tail cuff photoplethysmography	tail	345600		0			average of 4 daily averages of 3-4 measurements/day		13125	282
SHR/Fub	urine albumin excretion rate	controlled sodium content diet (0.2 %)	Poyan Mehr A, et al., Physiol Genomics 2003 Aug 15;14(3):209-16.	urine albumin amount	not specified	28 days	11			0.03	mg/d			enzyme linked immunosorbent assay	urine	0.0		0		rat albumin ELISA			13282	335
SS/Jr	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)	Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.	arterial blood pressure trait	male	64 days-70 days	20			221.0	mmHg	3.44	15.38	tail cuff plethysmography				0		average of 3-4 consistent readings			12454	266
SS.LEW-(D1Mco87-D1Rat71)/Jr	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)	Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.	arterial blood pressure trait	male	64 days-70 days	20			207.0	mmHg	2.87	12.84	tail cuff plethysmography				0		average of 3-4 consistent readings			12461	266
SS.LEW-(D1Uia2-D1Rat49)/Jr	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)	Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.	arterial blood pressure trait	male	64 days-70 days	20			187.0	mmHg	2.42	10.82	tail cuff plethysmography				0		average of 3-4 consistent readings			12465	266
SS.LEW-(D1Uia8-D1Rat18)/Mco	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)	Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.	arterial blood pressure trait	male	64 days-70 days	20			191.0	mmHg	2.24	10.02	tail cuff plethysmography				0		average of 3-4 consistent readings			12471	266
SS.LEW-(D17Rat65-D17Chm2)/Ayd	mean arterial blood pressure	controlled sodium content diet (2 %) (between 43 and 47 days)	Grondin M, et al., Physiol Genomics 2005 Mar 21;21(1):112-6. Epub 2005 Jan 4.	arterial blood pressure trait	male	88 days-92 days	5			173.0	mmHg	8.0	17.89	intra-aortic abdominal radiotelemetry				0			measure every 2 min for 24 hrs		12472	261
SS.LEW-(D1Mco87-D1Rat71)/Jr	body weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)	Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.	body mass	male	68 days-70 days	20			329.0	g	2.27	10.15	body weighing method				0					12494	266
SS.LEW-(D1Uia8-D1Rat124)/Mco	body weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)	Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.	body mass	male	68 days-70 days	20			298.0	g	2.53	11.31	body weighing method				0					12506	266
SS.LEW-(D1Uia8-D1Rat213)/Mco	body weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)	Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.	body mass	male	68 days-70 days	20			277.0	g	5.53	24.73	body weighing method				0					12507	266
SS.LEW-(D1Mco36-D1Rat49)/Jr	heart weight to body weight ratio	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)	Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.	heart mass	male	68 days-70 days	20			3.74	g/kg	0.04	0.17	post excision weight measurement				0					12561	266
WKY	heart weight to body weight ratio	controlled sodium content diet (0.4 %) (for 122 days) then controlled sodium content diet (1.4 %) (for 210 days)	Inomata H, et al., Hypertens Res 2005 Mar;28(3):273-81.	heart mass	male	360 days	4			2.5	g/kg	0.1	0.2	post excision weight measurement		0		0					12593	268
WKY	heart weight to body weight ratio	controlled sodium content diet (0.4 %) (for 122 days) then controlled sodium content diet (1.4 %) (for 210 days)	Inomata H, et al., Hypertens Res 2005 Mar;28(3):273-81.	heart mass	female	360 days	4			2.8	g/kg	0.1	0.2	post excision weight measurement		0		0					12596	268
SS/Jr	mean arterial blood pressure	controlled sodium content diet (8 %) (between 21 and 25 days)	Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5.	arterial blood pressure trait	male	82 days-86 days	69		serial mean	187.0	mmHg			vascular fluid filled catheter	femoral artery	345600		0		connected to solid-state transducer (Argon Medical Technologies, Athens, TX)	5 hr recording session - 1 min. averages, averaged over 4 days		12613	272
SS.LEW-(D18Rat67-D18Rat55)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days)	Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8.	arterial blood pressure trait	male	56 days	6			132.0	mmHg	8.0	19.6	intra-aortic abdominal radiotelemetry	aorta			0					12608	269
SS/Jr	body weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.	body mass	male	64 days-66 days	30			328.0	g	2.61	14.3	body weighing method		0		0					12866	313
SS.LEW-(D1Mco99-D1Rat49)/Mco	body weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.	body mass	male	64 days-66 days	20			302.0	g	1.89	8.45	body weighing method		0		0					12879	313
SS.LEW-(D1Mco36-D1Rat131)/1Mco	heart weight to body weight ratio	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.	heart mass	male	64 days-66 days	20			3.84	g/kg	0.03	0.15	post excision weight measurement		0		0					12897	313
SS.LEW-(D1Mco36-D1Mco101)/Mco	heart weight to body weight ratio	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.	heart mass	male	64 days-66 days	30			3.82	g/kg	0.02	0.13	post excision weight measurement		0		0					12902	313
SS.LEW-(D1Mco2-D1Rat49)/Jr	heart wet weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)	Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.	heart mass	male	68 days-70 days	20			1.14	g	0.01	0.05	post excision weight measurement				0					12525	266
SS.LEW-(D1Rat196-D1Mco36)/Jr	heart wet weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)	Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.	heart mass	male	68 days-70 days	20			1.17	g	0.01	0.03	post excision weight measurement				0					12533	266
SHRSP	body weight	controlled sodium content diet (0.4 %) (for 122 days) then controlled sodium content diet (1.4 %) (for 210 days)	Inomata H, et al., Hypertens Res 2005 Mar;28(3):273-81.	body mass	female	360 days	4			160.4	g	4.05	8.1	body weighing method		0		0					12539	268
SS/Jr	heart weight to body weight ratio	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)	Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.	heart mass	male	68 days-70 days	20			4.35	g/kg	0.05	0.22	post excision weight measurement				0					12553	266
SHR	heart wet weight	controlled sodium content diet (0.4 %) (for 122 days) then controlled sodium content diet (1.4 %) (for 210 days)	Inomata H, et al., Hypertens Res 2005 Mar;28(3):273-81.	heart mass	male	360 days	4			0.88	g	0.01	0.02	post excision weight measurement		0		0					12572	268
SHRSP	heart weight to body weight ratio	controlled sodium content diet (0.4 %) (for 122 days) then controlled sodium content diet (1.4 %) (for 210 days)	Inomata H, et al., Hypertens Res 2005 Mar;28(3):273-81.	heart mass	female	360 days	4			4.8	g/kg	0.5	1.0	post excision weight measurement		0		0					12571	268
SHR	systolic blood pressure	controlled sodium content diet (0.4 %) (for 63 days)	Inomata H, et al., Hypertens Res 2005 Mar;28(3):273-81.	arterial blood pressure trait	female	91 days	4		serial mean	152.2	mmHg	6.0	12.0	tail cuff photoplethysmography		0		0		UR1000; Ueda	average of 3 consistent readings		12583	268
SS/Jr	heart wet weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)	Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.	heart mass	male	68 days-70 days	20			1.26	g	0.05	0.21	digital scale post excision weight measurement		0		0					12675	282
SS/Jr	body weight	controlled sodium content diet (2 %) (for 28 days)	Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.	body mass	male	68 days-70 days	20			316.0	g	3.93	17.58	body weighing method				0					12942	305
SS/Jr	body weight	controlled sodium content diet (2 %) (for 28 days)	Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.	body mass	male	68 days-70 days	20			343.0	g	5.2	23.26	body weighing method				0					12948	305
SS.SHR-(D9Wox16-D9Rat76)/Mco	body weight	controlled sodium content diet (2 %) (for 28 days)	Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.	body mass	male	68 days-70 days	20			366.0	g	3.96	17.71	body weighing method				0					12953	305
SS/Jr	heart wet weight	controlled sodium content diet (2 %) (for 28 days)	Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.	heart mass	male	68 days-70 days	6			1.39	g	0.03	0.08	post excision weight measurement				0					12964	305
SS.SHR-(D9Mco72-D9Mco93)/Mco	heart wet weight	controlled sodium content diet (2 %) (for 28 days)	Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.	heart mass	male	68 days-70 days	6			1.14	g	0.03	0.07	post excision weight measurement				0					12972	305
SS.SHR-(D9Wox16-D9Rat76)/Mco	heart wet weight	controlled sodium content diet (2 %) (for 28 days)	Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.	heart mass	male	68 days-70 days	20			1.5	g	0.02	0.09	post excision weight measurement				0					12969	305
SS.SHR-(D9Mco74-D9Rat64)/Mco	heart wet weight	controlled sodium content diet (2 %) (for 28 days)	Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.	heart mass	male	68 days-70 days	5			1.11	g	0.03	0.07	post excision weight measurement				0					12971	305
SS/Jr	mean arterial blood pressure	controlled sodium content diet (2 %) (between 21 and 37 days)	Dutil J, et al., Hypertension 2005 Apr;45(4):557-64. Epub 2005 Feb 28.	arterial blood pressure trait	male	56 days-72 days	18			170.0	mmHg	4.0	16.97	intra-aortic abdominal radiotelemetry				0					12354	242
SS.SHR-(D8Uia1-D8Rat90)/Mco	serum triglyceride level	controlled sodium content diet (0.3 %)	Packard M, et al., Am J Physiol Renal Physiol. 2009 Apr;296(4):F839-46. Epub 2009 Jan 28.	blood triglyceride amount	male	28 days-84 days	8			45.0	mg/dl	1.4	3.96	automated blood analysis				0					12400	246
SS.LEW-(D5Rat130-D5Rat72)/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (for 14 days)	Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5.	arterial blood pressure trait	male	80 days	6		serial mean	195.0	mmHg			radiotelemetry	femoral artery			0		connected to solid-state transducer (Argon Medical Technologies, Athens, TX)	5 hr recording session - 1 min. averages, averaged over 4 days		12651	272
SS.LEW-(D10Mco84-D10Got93)/Mco	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)	Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.	arterial blood pressure trait	male	64 days-70 days	30		serial mean	189.0	mmHg	2.28	12.49	tail cuff photoplethysmography	tail	345600		0			average of 4 daily averages of 3-4 measurements/day		13136	282
SHR/Fub	urine albumin excretion rate	controlled sodium content diet (0.2 %)	Poyan Mehr A, et al., Physiol Genomics 2003 Aug 15;14(3):209-16.	urine albumin amount	not specified	196 days	11			2.6	mg/d			enzyme linked immunosorbent assay	urine	0.0		0		rat albumin ELISA			13285	335
SS/Jr	plasma sodium level	controlled sodium content diet (8 %) (between 8 and 10 days)	Huang BS, et al., Hypertension. 2007 Apr 9;.	blood sodium amount	male	43 days-52 days	12			147.0	mmol/l	2.0	6.93	sodium ion-selective electrode method				0		sodium ion-selective electrode			13322	344
LEW/Crlc	plasma potassium level	controlled sodium content diet (8 %) (between 8 and 10 days)	Huang BS, et al., Hypertension. 2007 Apr 9;.	blood potassium amount	male	43 days-52 days	8			5.0	mmol/l	0.3	0.85	potassium ion-selective electrode method				0		potassium ion-selective electrode			13323	344
LEW/Crlc	plasma chloride level	controlled sodium content diet (8 %) (between 8 and 10 days)	Huang BS, et al., Hypertension. 2007 Apr 9;.	blood chloride amount	male	43 days-52 days	8			103.0	mmol/l	2.0	5.66	chloride ion-selective electrode method		0.0		0		chloride ion-selective electrode			13327	344
SS.SHR-(D9Mco72-D9Mco109)/Mco	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	arterial blood pressure trait	not specified	65 days-70 days	0			188.0	mmHg	3.21		tail cuff plethysmography		0.0		0					67514	749
SS.SHR-(D9Mco72-D9Mco106)/Mco	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	arterial blood pressure trait	not specified	65 days-70 days	0			176.0	mmHg	5.24		tail cuff plethysmography		0.0		0					67520	749
SS/Jr	body weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	body mass	not specified	0 days	0			307.0	g	4.93		body weighing method		0.0		0					67527	749
SS.SHR-(D9Rat7-D9Rat84)/Mco	body weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	body mass	not specified	0 days	0			339.0	g	3.37		body weighing method		0.0		0					67538	749
SS/Jr	heart wet weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	heart mass	not specified	0 days	0			1.38	g	0.02		post excision weight measurement		0.0		0					67550	749
SS.SHR-(D9Mco72-D9Mco105)/Mco	heart weight to body weight ratio	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	heart mass	not specified	0 days	0			4.3	g/kg	0.16		post excision weight measurement		0.0		0					67569	749
SS.SHR-(D9Rat7-D9Mco91)/Mco	heart weight to body weight ratio	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	heart mass	not specified	0 days	0			4.16	g/kg	0.06		post excision weight measurement		0.0		0					67576	749
SS.SHR-(D9Mco72-D9Mco105)/Mco	urine total protein excretion rate	controlled sodium content diet (2 %) (between 30 and 33 days)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	total urine protein amount	not specified	78 days-83 days	0			212.0	mg/d	14.66		pyrogallol red-molybdate complex-based urine total protein analysis		0.0		0					67587	749
SS/Jr	urine total protein excretion rate	controlled sodium content diet (2 %) (between 30 and 33 days)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	total urine protein amount	not specified	78 days-83 days	0			94.0	mg/d	7.54		pyrogallol red-molybdate complex-based urine total protein analysis		0.0		0					67584	749
SS-Chr 16BN/Mcwi	percent change in ventilation	controlled sodium content diet (0 %) then controlled air oxygen content (12 %) (between 0.1 and 0.1 hours)	PhysGen Respiratory data	pulmonary ventilation trait	female	82 days-99 days	7	%change=VE during7-9 min hypoxia/control during standard conditions		167.62	%	15.92	42.13	stop flow air displacement plethysmography				0				Moms and pups used in studies were fed Dyets	17915	381
SS.LEW-(D10Mit10-D10Mgh1)/Jr	heart wet weight	controlled sodium content diet (2 %) (between 24 and 27 days)	Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23	heart mass	not specified	64 days-71 days	20			1.1	g	0.01	0.05	post excision weight measurement		0		0				4 rats per cage, 2 SR/Jr 2 LEW/NCrl	64763	222
SS/Jr	heart wet weight	controlled sodium content diet (2 %) (between 24 and 27 days)	Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23	heart mass	not specified	64 days-71 days	19			1.21	g	0.02	0.07	post excision weight measurement		0		0				4 rats per cage, 2 SR/Jr 2 LEW/NCrl	64764	222
SS/JrHsdMcwi	percent change in ventilation	controlled sodium content diet (0 %) then controlled air oxygen content (12 %) (between 0.1 and 0.1 hours)	PhysGen Respiratory data	pulmonary ventilation trait	female	82 days-99 days	10	%change=VE during7-9 min hypoxia/control during standard conditions		148.65	%	12.89	40.77	stop flow air displacement plethysmography				0				Moms and pups used in studies were fed Dyets	17922	381
SS.LEW-(D18Rat30-D18Chm29)/Ayd	heart weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	heart mass	male	98 days	8			3.5	g/kg	0.1	0.28	post excision weight measurement		0		0					64802	226
SS.LEW-(D18Rat30-D18Chm29)/Ayd	body weight	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	body mass	male	98 days	8			378.0	g	9.0	25.46	body weighing method		0.0		0					64803	226
SS/Jr	heart rate	controlled sodium content diet (2 %) (for 37 days)	Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.	heart pumping trait	male	75 days-79 days	5			378.0	beats/min	9.18	20.53	intra-aortic abdominal radiotelemetry		172800		0					64986	305
SS.LEW-(D16Rat112-D16Chm60)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 23 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	arterial blood pressure trait	male	56 days-60 days	8			137.0	mmHg	0.71	2.0	radiotelemetry		86400		0			two 24 hours widely separated periods, data represent averages of all readings over the 24-h measurements		64999	542
LEW	body weight	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	body mass	male	77 days	14			299.2	g	6.76	25.3	body weighing method		0		0					65004	542
SS.LEW-(D10Got112-Igfbp4)/Ayd	body weight	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	body mass	male	77 days	5			318.8	g	9.03	20.2	body weighing method		0		0					65010	542
SS/Jr	heart rate	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	heart pumping trait	male	77 days	40			414.0	beats/min	4.27	27.0	transthoracic echocardiography		0		0					65013	542
SS.BN-(D13Rat7-D13Rat127)/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 16 and 19 days)	Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12.	arterial blood pressure trait	male	86 days-89 days	12			173.0	mmHg	5.4	18.71	vascular fluid filled catheter	left femoral artery	14400		0		on 3 consecutive days			65162	15
SS.BN-(D13Rat20-D13Got22)/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 16 and 19 days)	Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12.	arterial blood pressure trait	female	86 days-89 days	12			184.0	mmHg	6.2	21.48	vascular fluid filled catheter	left femoral artery	14400		0		on 3 consecutive days			65165	15
Hsd:SD	percent change in ventilation	controlled sodium content diet (0 %) then controlled air oxygen content (12 %) (between 0.1 and 0.1 hours)	PhysGen Respiratory data	pulmonary ventilation trait	male	82 days-99 days	15	%change=VE during7-9 min hypoxia/control during standard conditions		141.14	%	5.99	23.18	stop flow air displacement plethysmography				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	17018	381
Hsd:SD	percent change in ventilation	controlled sodium content diet (0 %) then controlled air oxygen content (12 %) (between 0.1 and 0.1 hours)	PhysGen Respiratory data	pulmonary ventilation trait	female	82 days-99 days	15	%change=VE during7-9 min hypoxia/control during standard conditions		138.6	%	6.48	25.11	stop flow air displacement plethysmography				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	17019	381
FHH-Agtr1bm1Mcwi	body length, nose to tail	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	male	70 days-84 days	12			40.63	cm	0.89	3.08	in vivo ruler method				0					63662	529
FHH-F10m1Mcwi	body length, nose to tail	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	female	70 days-84 days	10			38.45	cm	0.22	0.69	in vivo ruler method				0					63676	529
FHH-F10m2Mcwi	body length, nose to tail	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	female	70 days-84 days	11			38.5	cm	0.38	1.25	in vivo ruler method				0					63690	529
F344-DccTn(sb-T2/Bart3)2.205Mcwi	body length, nose to tail	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	female	70 days-84 days	6			33.42	cm	0.27	0.66	in vivo ruler method				0					63693	529
FHH-Adipoqm3Mcwi	body length, nose to tail	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	female	70 days-84 days	7			37.86	cm	0.51	1.35	in vivo ruler method				0					63707	529
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi	body length, nose to tail	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	male	70 days-84 days	4			37.38	cm	0.69	1.38	in vivo ruler method				0					63725	529
FHH-Adipoqm1Mcwi	heart left ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart left ventricle mass	female	70 days-84 days	10			0.52	g	0.01	0.04	digital scale post excision weight measurement				0					63727	529
FHH-Adipoqm2Mcwi	heart left ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart left ventricle mass	female	70 days-84 days	15			0.63	g	0.05	0.18	digital scale post excision weight measurement				0					63728	529
FHH-Agtr1bm1Mcwi	heart left ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart left ventricle mass	male	70 days-84 days	15			0.64	g	0.01	0.06	digital scale post excision weight measurement				0					63734	529
FHH-Adipoqm1Mcwi	heart left ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart left ventricle mass	male	70 days-84 days	8			0.73	g	0.02	0.05	digital scale post excision weight measurement				0					63744	529
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi	heart left ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart left ventricle mass	female	70 days-84 days	8			0.4	g	0.03	0.08	digital scale post excision weight measurement				0					63758	529
F344-DccTn(sb-T2/Bart3)2.205Mcwi	heart left ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart left ventricle mass	female	70 days-84 days	6			0.38	g	0.01	0.01	digital scale post excision weight measurement				0					63765	529
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi	heart left ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart left ventricle mass	male	70 days-84 days	1			0.6	g			digital scale post excision weight measurement				0					63766	529
FHH/EurMcwi	heart left ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart left ventricle mass	female	70 days-84 days	28			0.53	g	0.01	0.06	digital scale post excision weight measurement				0					63770	529
F344-Plcb3Tn(sb-T2/Bart3)2.69Mcwi	heart left ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart left ventricle mass	female	70 days-84 days	4			0.37	g	0.01	0.02	digital scale post excision weight measurement				0					63775	529
FHH-Adipoqm3Mcwi	heart left ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart left ventricle mass	female	70 days-84 days	7			0.55	g	0.01	0.03	digital scale post excision weight measurement				0					63779	529
FHH/EurMcwi	heart left ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart left ventricle mass	male	70 days-84 days	172			0.7	g	0.01	0.08	digital scale post excision weight measurement				0					63781	529
FHH-Tlr4m1Mcwi	heart left ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart left ventricle mass	male	70 days-84 days	13			0.66	g	0.02	0.05	digital scale post excision weight measurement				0					63785	529
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi	heart left ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart left ventricle mass	female	70 days-84 days	2			0.37	g	0.01	0.02	digital scale post excision weight measurement				0					63787	529
LE/BluGill	percent change in ventilation	controlled sodium content diet (0 %) then controlled air oxygen content (12 %) (between 0 and 0.1 hours)	PhysGen Respiratory data	pulmonary ventilation trait	male	82 days-99 days	13	%change=VE during 2-3 min hypoxia/control during standard conditions		151.33	%	5.57	20.09	stop flow air displacement plethysmography				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	19309	381
SHR.SS-(D13Rat1-D13Mgh6)/Mco	serum total cholesterol level	controlled sodium content diet (0.3 %)	Packard M, et al., Am J Physiol Renal Physiol. 2009 Apr;296(4):F839-46. Epub 2009 Jan 28.	blood cholesterol amount	male	84 days	8			40.0	mg/dl	1.8	5.09	automated blood analysis		0		0					64809	246
SS.BN-(D13Rat91-D13Got45)/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 16 and 19 days)	Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12.	arterial blood pressure trait	female	86 days-89 days	12			169.0	mmHg	4.4	15.24	vascular fluid filled catheter	left femoral artery	14400		0		on 3 consecutive days			65176	15
SS.BN-(D13Rat178-D13Got45)/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 16 and 19 days)	Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12.	arterial blood pressure trait	male	86 days-89 days	12			190.0	mmHg	2.8	9.7	vascular fluid filled catheter	left femoral artery	14400		0		on 3 consecutive days			65185	15
SS.BN-(D13Rat127-D13Rat46)/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 16 and 19 days)	Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12.	arterial blood pressure trait	female	86 days-89 days	12			154.0	mmHg	3.1	10.74	vascular fluid filled catheter	left femoral artery	14400		0		on 3 consecutive days			65188	15
SS/Jr	systolic blood pressure	controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)	Joe B, et al., Hum Mol Genet. 2009 Aug 1;18(15):2825-38. Epub 2009 May 7.	arterial blood pressure trait	male	64 days-70 days	20		serial mean	207.0	mmHg	4.7	21.02	tail cuff plethysmography		345600		0		Rats warmed to 28 degrees C for measurement.			65305	565
SS-Klf4m3Mcwi	heart right ventricle wet weight	controlled sodium content diet (1 %) (for 14 days)	PhysGen General data	heart right ventricle mass	female	70 days-84 days	9			0.16	g	0.0	0.01	digital scale post excision weight measurement				0					63248	529
SS-Cpt2m1Mcwi	body length, nose to tail	controlled sodium content diet (1 %) (for 14 days)	PhysGen General data	body length	female	70 days-84 days	2			38.5	cm	0.5	0.71	in vivo ruler method				0					63260	529
FHH-Adipoqm2Mcwi	heart right ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart right ventricle mass	female	70 days-84 days	15			0.18	g	0.03	0.1	digital scale post excision weight measurement				0					63266	529
F344-Elmod3Tn(sb-T2/Bart3)2.42Mcwi	heart right ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart right ventricle mass	male	70 days-84 days	7			0.17	g	0.01	0.02	digital scale post excision weight measurement				0					63271	529
F344-Plce1Tn(sb-T2/Bart3)2.146Mcwi	heart right ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart right ventricle mass	male	70 days-84 days	8			0.15	g	0.0	0.01	digital scale post excision weight measurement				0					63274	529
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi	heart right ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart right ventricle mass	female	70 days-84 days	2			0.12	g	0.0	0.01	digital scale post excision weight measurement				0					63275	529
F344-Plce1Tn(sb-T2/Bart3)2.146Mcwi	heart right ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart right ventricle mass	female	70 days-84 days	5			0.11	g	0.0	0.01	digital scale post excision weight measurement				0					63283	529
FHH-Procm1Mcwi	heart right ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart right ventricle mass	female	70 days-84 days	9			0.18	g	0.02	0.06	digital scale post excision weight measurement				0					63288	529
F344/NHsd	heart right ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart right ventricle mass	male	70 days-84 days	10			0.11	g	0.0	0.01	digital scale post excision weight measurement				0					63290	529
F344-DccTn(sb-T2/Bart3)2.205Mcwi	heart right ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart right ventricle mass	female	70 days-84 days	6			0.1	g	0.0	0.0	digital scale post excision weight measurement				0					63303	529
FHH/EurMcwi	heart right ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart right ventricle mass	female	70 days-84 days	28			0.16	g	0.01	0.03	digital scale post excision weight measurement				0					63308	529
FHH-Adra1am1Mcwi	heart right ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart right ventricle mass	female	70 days-84 days	9			0.14	g	0.0	0.0	digital scale post excision weight measurement				0					63322	529
FHH-Tlr4m1Mcwi	heart right ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart right ventricle mass	female	70 days-84 days	11			0.14	g	0.01	0.02	digital scale post excision weight measurement				0					63327	529
FHH-Lcatm1Mcwi	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	kidney mass	male	70 days-84 days	13			1.13	g	0.03	0.1	digital scale post excision weight measurement				0					63341	529
FHH-Adipoqm1Mcwi	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	kidney mass	male	70 days-84 days	8			1.19	g	0.03	0.07	digital scale post excision weight measurement				0					63354	529
FHH-Ccr2m1Mcwi	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	kidney mass	female	70 days-84 days	7			0.88	g	0.02	0.05	digital scale post excision weight measurement				0					63357	529
F344-Plce1Tn(sb-T2/Bart3)2.146Mcwi	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	kidney mass	female	70 days-84 days	5			0.62	g	0.01	0.03	digital scale post excision weight measurement				0					63355	529
FHH-Procm1Mcwi	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	kidney mass	female	70 days-84 days	9			0.95	g	0.06	0.17	digital scale post excision weight measurement				0					63360	529
FHH-F10m2Mcwi	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	kidney mass	male	70 days-84 days	17			1.23	g	0.03	0.12	digital scale post excision weight measurement				0					63363	529
FHH-Htr1am1Mcwi	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	kidney mass	male	70 days-84 days	22			1.14	g	0.02	0.1	digital scale post excision weight measurement				0					63369	529
FHH/EurMcwi	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	kidney mass	female	70 days-84 days	28			0.91	g	0.02	0.13	digital scale post excision weight measurement				0					63380	529
BN-Lcatm3Mcwi	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	kidney mass	male	70 days-84 days	1			0.88	g			digital scale post excision weight measurement				0					63384	529
FHH-Egln3m1Mcwi	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	kidney mass	male	70 days-84 days	6			1.14	g	0.05	0.11	digital scale post excision weight measurement				0					63387	529
FHH-Tlr4m1Mcwi	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	kidney mass	male	70 days-84 days	13			1.12	g	0.03	0.09	digital scale post excision weight measurement				0					63395	529
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	kidney mass	male	70 days-84 days	4			0.98	g	0.01	0.03	digital scale post excision weight measurement				0					63407	529
FHH-Ghsrm1Mcwi	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart mass	female	70 days-84 days	10			0.84	g	0.03	0.08	digital scale post excision weight measurement				0					63450	529
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart mass	male	70 days-84 days	1			0.87	g			digital scale post excision weight measurement				0					63448	529
BN-Lcatm3Mcwi	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart mass	male	70 days-84 days	1			0.76	g			digital scale post excision weight measurement				0					63456	529
FHH-Adra1am1Mcwi	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart mass	female	70 days-84 days	9			0.79	g	0.01	0.03	digital scale post excision weight measurement				0					63466	529
FHH-Tlr4m1Mcwi	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart mass	female	70 days-84 days	11			0.8	g	0.03	0.09	digital scale post excision weight measurement				0					63471	529
BN/NHsdMcwi	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart mass	male	70 days-84 days	45			0.74	g	0.01	0.08	digital scale post excision weight measurement				0					63476	529
SS-Cpt2m1Mcwi	heart left ventricle wet weight	controlled sodium content diet (1 %) (for 14 days)	PhysGen General data	heart left ventricle mass	female	70 days-84 days	2			0.76	g	0.0	0.01	digital scale post excision weight measurement				0					63486	529
SS-Sod3m1Mcwi	heart left ventricle wet weight	controlled sodium content diet (1 %) (for 14 days)	PhysGen General data	heart left ventricle mass	female	70 days-84 days	13			0.63	g	0.02	0.06	digital scale post excision weight measurement				0					63489	529
SS-Ghsrm3Mcwi	body length, nose to rump	controlled sodium content diet (1 %) (for 14 days)	PhysGen General data	body length	male	70 days-84 days	2			23.5	cm	0.5	0.71	in vivo ruler method				0					63490	529
SS/JrHsdMcwi	body length, nose to rump	controlled sodium content diet (1 %) (for 14 days)	PhysGen General data	body length	female	70 days-84 days	17			21.38	cm	0.34	1.42	in vivo ruler method				0					63498	529
SS-Sod3m1Mcwi	body length, nose to rump	controlled sodium content diet (1 %) (for 14 days)	PhysGen General data	body length	female	70 days-84 days	13			21.08	cm	0.26	0.93	in vivo ruler method				0					63499	529
FHH-Agtr1bm1Mcwi	body length, nose to rump	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	male	70 days-84 days	12			23.38	cm	0.27	0.93	in vivo ruler method				0					63508	529
FHH-Tgfbr2m2Mcwi	body length, nose to rump	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	female	70 days-84 days	14			21.96	cm	0.12	0.46	in vivo ruler method				0					63509	529
BN-Tgfbr2m1Mcwi	body length, nose to rump	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	male	70 days-84 days	7			23.21	cm	0.15	0.39	in vivo ruler method				0					63517	529
F344/NHsd	body length, nose to rump	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	male	70 days-84 days	10			29.95	cm	2.66	8.42	in vivo ruler method				0					63526	529
FHH-F10m2Mcwi	body length, nose to rump	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	female	70 days-84 days	11			21.27	cm	0.41	1.35	in vivo ruler method				0					63536	529
FHH-Nr4a1m1Mcwi	body length, nose to rump	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	female	70 days-84 days	13			21.65	cm	0.2	0.72	in vivo ruler method				0					63538	529
FHH-Ghsrm1Mcwi	body length, nose to rump	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	female	70 days-84 days	10			22.5	cm	0.11	0.33	in vivo ruler method				0					63542	529
F344-AbatTn(sb-T2/Bart3)2.163Mcwi	body length, nose to rump	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	female	70 days-84 days	5			20.2	cm	0.2	0.45	in vivo ruler method				0					63557	529
BN/NHsdMcwi	body length, nose to rump	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	male	70 days-84 days	45			22.29	cm	0.16	1.11	in vivo ruler method				0					63568	529
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi	body length, nose to rump	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	male	70 days-84 days	4			23.0	cm	0.0	0.0	in vivo ruler method				0					63571	529
SS-Cpt2m1Mcwi	left kidney wet weight	controlled sodium content diet (1 %) (for 14 days)	PhysGen General data	kidney mass	male	70 days-84 days	7			1.45	g	0.04	0.11	digital scale post excision weight measurement				0					63573	529
SS/JrHsdMcwi	left kidney wet weight	controlled sodium content diet (1 %) (for 14 days)	PhysGen General data	kidney mass	male	70 days-84 days	47			1.43	g	0.03	0.21	digital scale post excision weight measurement				0					63574	529
BN-Tgfbr2m1Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body mass	female	70 days-84 days	3			148.33	g	2.33	4.04	whole body digital scale				0					63588	529
FHH-Tgfbr2m2Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body mass	female	70 days-84 days	14			182.57	g	2.81	10.52	whole body digital scale				0					63591	529
FHH-Htr1am1Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body mass	male	70 days-84 days	22			256.86	g	3.44	16.15	whole body digital scale				0					63615	529
FHH-Egln3m1Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body mass	male	70 days-84 days	6			264.0	g	6.39	15.66	whole body digital scale				0					63633	529
F344-DccTn(sb-T2/Bart3)2.205Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body mass	male	70 days-84 days	7			275.14	g	10.05	26.59	whole body digital scale				0					63634	529
FHH/EurMcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body mass	male	70 days-84 days	173			275.19	g	2.26	29.78	whole body digital scale				0					63637	529
F344-Elmod3Tn(sb-T2/Bart3)2.42Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	3			-8.07	null	0.04	0.08	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		63068	528
F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	3			-8.06	null	0.2	0.34	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		63077	528
FHH-Htr1am1Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	12			-8.03	null	0.07	0.23	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		63079	528
F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	1			-8.24	null			wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		63082	528
FHH-Htr1am1Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	18			-8.26	null	0.06	0.28	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		63087	528
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	4			-8.21	null	0.15	0.3	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		63088	528
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	3			-8.05	null	0.1	0.17	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		63095	528
FHH/EurMcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	119			-8.15	null	0.03	0.33	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		63108	528
F344-AbatTn(sb-T2/Bart3)2.163Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	1			-8.89	null			wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		63110	528
FHH-Egln3m1Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	13			-8.21	null	0.11	0.41	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		63118	528
FHH-Agtr1bm1Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	4			1.23	g/mg	0.07	0.15	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63132	528
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	3			-7.81	null	0.14	0.24	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		63124	528
BN/NHsdMcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	8			-7.96	null	0.07	0.21	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		63121	528
FHH-Adipoqm2Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	9			1.3	g/mg	0.08	0.24	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63144	528
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	8			1.15	g/mg	0.15	0.41	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63155	528
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	4			0.83	g/mg	0.22	0.44	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63157	528
FHH-F10m2Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	12			1.6	g/mg	0.08	0.29	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63159	528
F344-DccTn(sb-T2/Bart3)2.205Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	3			1.27	g/mg	0.32	0.55	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63162	528
F344-DccTn(sb-T2/Bart3)2.205Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	5			1.3	g/mg	0.07	0.15	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63173	528
BN/NHsdMcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	8			2.07	g/mg	0.12	0.34	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63190	528
F344-Nrg1Tn(sb-T2/Bart3)2.183Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	5			1.17	g/mg	0.09	0.2	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63191	528
SS/JrHsdMcwi	body weight	controlled sodium content diet (1 %) (for 14 days)	PhysGen Vascular data	body mass	male	70 days-84 days	11			299.18	g	5.3	17.59	whole body digital scale				0					63196	528
SS-Cpt2m1Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (1 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	1			1.81	E-7mole			wire myography using a Digi-Med tissue force analysis system with force transducer				0					63220	528
SS-Sod3m1Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (1 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	12			2.57	E-7mole	0.98	3.38	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63223	528
SS/Jr	systolic blood pressure	controlled sodium content diet (1 %) (for 60 days) then controlled sodium content diet (0.2 %) (between 41 and 44 days)	Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41	arterial blood pressure trait	both	131 days-134 days	21	data obtained at three consistent sessions per day	serial mean	244.0	mmHg			tail cuff plethysmography		345600		0					65963	650
SS.SR-(D13N1-D13Mit1)/Jr	systolic blood pressure	controlled sodium content diet (0.2 %) (for 24 days) then controlled sodium content diet (4 %) (for 24 days)	Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41	arterial blood pressure trait	not specified	65 days-68 days	26	data obtained at three consistent sessions per day	serial mean	217.0	mmHg			tail cuff plethysmography		345600		0					66029	650
SS/Jr	heart weight to body weight ratio	controlled sodium content diet (0.2 %) (for 10 days) then controlled sodium content diet (2 %) (for 24 days)	Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41	heart mass	not specified	68 days	27			4.05	g/kg			post excision weight measurement		0		0					66031	650
SS/JrRkb	body weight	controlled sodium content diet (0.2 %) (for 56 days)	Wendt N, et al., J Hypertens. 2007 Jan;25(1):95-102.	body mass	male	98 days	14			371.0	g	5.0	18.71	body weighing method		0		0					66082	669
SS-Chr 19SHR/Rkb	body weight	controlled sodium content diet (0.2 %) (for 56 days)	Wendt N, et al., J Hypertens. 2007 Jan;25(1):95-102.	body mass	male	98 days	20			355.0	g	8.0	35.78	body weighing method		0		0					66084	669
SS-Ube2q2em3Mcwi+/+	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	1			1.92	g			post excision weight measurement				0				-	66209	717
SS-Gpr183em1Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	6			1.57	g	0.07	0.18	post excision weight measurement				0				-	66207	717
SS-Gpr183em2Mcwi+/+	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	2			1.66	g	0.03	0.04	post excision weight measurement				0				-	66220	717
SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi-/+	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	1			1.26	g			post excision weight measurement				0				-	66225	717
SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi+/+	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	2			1.46	g	0.06	0.08	post excision weight measurement				0				-	66223	717
SS-Cybaem1Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	6			1.44	g	0.06	0.15	post excision weight measurement				0				-	66227	717
SS-Mmp2em1Mcwi+/+	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	1			1.45	g			post excision weight measurement				0				-	66229	717
SS-Gpr183em1Mcwi+/+	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	4			1.45	g	0.07	0.13	post excision weight measurement				0				-	66228	717
SS-Gpr183em3Mcwi+/+	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	4			1.55	g	0.05	0.09	post excision weight measurement				0				-	66233	717
SS-Apoeem7Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	5			1.42	g	0.04	0.09	post excision weight measurement				0				-	66231	717
SS-Nox4em2Mcwi+/+	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	3			1.28	g	0.08	0.13	post excision weight measurement				0				-	66235	717
SS-Nckap5em2Mcwi+/+	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	2			1.63	g	0.04	0.06	post excision weight measurement				0				-	66237	717
SS-Mmp2em2Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	6			1.36	g	0.06	0.14	post excision weight measurement				0				-	66238	717
SS-Renem1Mcwi+/+	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	4			1.52	g	0.06	0.11	post excision weight measurement				0				-	66246	717
SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	4			1.43	g	0.06	0.13	post excision weight measurement				0				-	66245	717
SS-Mthfrem1Mcwi-/+	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	8			1.67	g	0.09	0.25	post excision weight measurement				0				-	66259	717
SS-Ube2q2em3Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	2			1.4	g	0.01	0.02	post excision weight measurement				0				-	66263	717
SS-Ube2q2em3Mcwi+/+	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	1			376.0	g			whole body digital scale				0				-	66271	717
SS-Gpr183em2Mcwi+/+	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	2			336.5	g	10.5	14.8	whole body digital scale				0				-	66282	717
SS-Itga9em1Mcwi+/+	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	4			317.0	g	9.4	18.9	whole body digital scale				0				-	66315	717
SS-Mas1em1Mcwi+/+	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	2			307.0	g	15.0	21.2	whole body digital scale				0				-	66322	717
SS-Ube2q2em3Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	1			358.0	beats/min			radiotelemetry	carotid artery			0				-	66333	717
FHH-Chr 1BN-Sorcs1em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			338.0	beats/min	38.0	53.74	radiotelemetry	carotid artery			0				-	66336	717
SS-Tfdp2em2Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			373.5	beats/min	7.5	10.61	radiotelemetry	carotid artery			0				-	66339	717
SS-Bcas3em4Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	3			365.0	beats/min	3.51	6.08	radiotelemetry	carotid artery			0				-	66341	717
SS-Mthfrem1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	1			338.0	beats/min			radiotelemetry	carotid artery			0				-	66335	717
SS-Mmp2em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	1			359.0	beats/min			radiotelemetry	carotid artery			0				-	66352	717
SS-Nckap5em2Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			328.5	beats/min	6.5	9.19	radiotelemetry	carotid artery			0				-	66359	717
SS-Apoeem8Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			354.0	beats/min	23.0	32.53	radiotelemetry	carotid artery			0				-	66361	717
SS-Alms1em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	1			360.0	beats/min			radiotelemetry	carotid artery			0				-	66364	717
SS-Tfdp2em2Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	3			337.33	beats/min	21.76	37.69	radiotelemetry	carotid artery			0				-	66372	717
SS-Rag1em1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	1/3 systolic pressure + 2/3 diastolic pressure		132.5	mmHg	10.59	21.17	radiotelemetry	carotid artery			0				-	66390	717
SS-Alms1em1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	5	1/3 systolic pressure + 2/3 diastolic pressure		150.4	mmHg	8.63	19.3	radiotelemetry	carotid artery			0				-	66389	717
FHH-Chr 1BN-Sorcs1em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		130.5	mmHg	12.5	17.68	radiotelemetry	carotid artery			0				-	66396	717
SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	1	1/3 systolic pressure + 2/3 diastolic pressure		132.0	mmHg			radiotelemetry	carotid artery			0				-	66407	717
SS-Apoeem7Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	3	1/3 systolic pressure + 2/3 diastolic pressure		122.33	mmHg	4.91	8.5	radiotelemetry	carotid artery			0				-	66409	717
SS-Apoeem7Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	5	1/3 systolic pressure + 2/3 diastolic pressure		134.8	mmHg	8.52	19.06	radiotelemetry	carotid artery			0				-	66414	717
SS-Mas1em1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	1/3 systolic pressure + 2/3 diastolic pressure		141.0	mmHg	14.46	28.93	radiotelemetry	carotid artery			0				-	66422	717
SS-Ets1em1Mcwi-/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	7	1/3 systolic pressure + 2/3 diastolic pressure		123.71	mmHg	5.02	13.28	radiotelemetry	carotid artery			0				-	66429	717
SS-Itga9em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	1/3 systolic pressure + 2/3 diastolic pressure		140.0	mmHg	4.92	9.83	radiotelemetry	carotid artery			0				-	66435	717
SS-Mmp2em1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	5	/3 systolic pressure + 2/3 diastolic pressure		136.4	mmHg	5.59	12.5	radiotelemetry	carotid artery			0				-	66448	717
SS-Acad10em2Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	13	/3 systolic pressure + 2/3 diastolic pressure		141.62	mmHg	6.7	24.17	radiotelemetry	carotid artery			0				-	66454	717
SS-Ube2q2em3Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	1	/3 systolic pressure + 2/3 diastolic pressure		169.0	mmHg			radiotelemetry	carotid artery			0				-	66453	717
FHH-Chr 1BN-Sorcs1em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	/3 systolic pressure + 2/3 diastolic pressure		125.0	mmHg	6.0	8.49	radiotelemetry	carotid artery			0				-	66456	717
SS-Gpr183em3Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	3	/3 systolic pressure + 2/3 diastolic pressure		221.67	mmHg	92.67	160.51	radiotelemetry	carotid artery			0				-	66476	717
SS-Chr 5BN-Cyp4a2em1Mcwi-/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	/3 systolic pressure + 2/3 diastolic pressure		127.5	mmHg	2.5	3.54	radiotelemetry	carotid artery			0				-	66485	717
SS-Cybaem1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	1	/3 systolic pressure + 2/3 diastolic pressure		116.0	mmHg			radiotelemetry	carotid artery			0				-	66493	717
SS-Chr 5BN-Cyp4a2em1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	6	/3 systolic pressure + 2/3 diastolic pressure		125.17	mmHg	6.23	15.26	radiotelemetry	carotid artery			0				-	66498	717
SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi+/+	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	2			120.8	mg/d	25.54	36.11	automated urine analysis				0				-	66527	717
SS-Gpr183em3Mcwi+/+	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	4			124.52	mg/d	31.69	63.39	automated urine analysis				0				-	66537	717
SS-Chr 5BN-Cyp4a2em1Mcwi-/-	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	7			132.1	mg/d	10.01	26.5	automated urine analysis				0				-	66559	717
SS-Nox4em2Mcwi-/+	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	2			97.16	mg/d	7.03	9.94	automated urine analysis				0				-	66565	717
SS-Acad10em2Mcwi+/+	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	5			96.08	mg/d	22.3	49.86	automated urine analysis				0				-	66564	717
SS-Ube2q2em3Mcwi-/-	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	2			68.98	mg/d	3.36	4.75	automated urine analysis				0				-	66566	717
SS-Mas1em1Mcwi+/+	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	2			159.63	mg/d	7.7	10.88	automated urine analysis				0				-	66563	717
FHH-Chr 1BN-Sorcs1em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			318.5	beats/min	35.5	50.2	radiotelemetry	carotid artery			0				-	66577	717
SS-Nckap5em1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	6			344.67	beats/min	7.6	18.62	radiotelemetry	carotid artery			0				-	66579	717
SS-Chr 5BN-Cyp4a2em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	3			334.33	beats/min	4.33	7.51	radiotelemetry	carotid artery			0				-	66589	717
SS-Tfdp2em2Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			356.0	beats/min	3.0	4.24	radiotelemetry	carotid artery			0				-	66580	717
SS-Cybaem1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	5			330.4	beats/min	12.76	28.54	radiotelemetry	carotid artery			0				-	66591	717
SS-Rag1em2Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	6			326.0	beats/min	17.43	42.7	radiotelemetry	carotid artery			0				-	66600	717
SS-Ube2q2em3Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			320.5	beats/min	28.5	40.31	radiotelemetry	carotid artery			0				-	66626	717
SS-Adra2aem1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	8			358.13	beats/min	7.03	19.89	radiotelemetry	carotid artery			0				-	43443	421
SS-Sh2b3em1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	14	1/3 systolic pressure + 2/3 diastolic pressure		120.79	mmHg	2.3	8.62	radiotelemetry	carotid artery			0				-	43456	421
SS-Rasgrp3em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	5	1/3 systolic pressure + 2/3 diastolic pressure		130.0	mmHg	4.24	9.49	radiotelemetry	carotid artery			0				-	43459	421
SS-Ulk3em4Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		147.0	mmHg	23.0	32.53	radiotelemetry	carotid artery			0				-	43464	421
SS-Ulk3em4Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	15	1/3 systolic pressure + 2/3 diastolic pressure		141.67	mmHg	6.73	26.05	radiotelemetry	carotid artery			0				-	43466	421
SS-Rasgrp3em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	1/3 systolic pressure + 2/3 diastolic pressure		126.75	mmHg	4.94	9.88	radiotelemetry	carotid artery			0				-	43475	421
SS-Wdr72em2Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	7	1/3 systolic pressure + 2/3 diastolic pressure		142.57	mmHg	3.27	8.66	radiotelemetry	carotid artery			0				-	43477	421
SS-Hexim2em4Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	10	1/3 systolic pressure + 2/3 diastolic pressure		129.0	mmHg	3.21	10.14	radiotelemetry	carotid artery			0				-	43486	421
SS-Sh2b3em1Mcwi+/+	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	1			318.0	g			whole body digital scale				0				-	43492	421
SS-Sh2b3em1Mcwi-/+	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	3			300.7	g	1.8	3.1	whole body digital scale				0				-	43494	421
SS-Ulk3em4Mcwi-/+	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	4			301.2	g	7.7	15.4	whole body digital scale				0				-	43498	421
SS-Sh2b3em1Mcwi-/-	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	16			81.78	mg/d	5.64	22.56	automated urine analysis				0				-	43503	421
SS-Adra2aem1Mcwi-/-	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	8			70.43	mg/d	7.87	22.25	automated urine analysis				0				-	43505	421
SS-Sh2b3em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	1			364.0	beats/min			radiotelemetry	carotid artery			0				-	43524	421
SS-Ulk3em4Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			357.5	beats/min	10.5	14.85	radiotelemetry	carotid artery			0				-	43527	421
SS-Agtrapem4Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	7			340.67	beats/min	6.17	16.33	radiotelemetry	carotid artery			0				-	43532	421
SS-Sh2b3em1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	12	1/3 systolic pressure + 2/3 diastolic pressure		124.25	mmHg	2.86	9.9	radiotelemetry	carotid artery			0				-	43535	421
SS-Sh2b3em1Mcwi-/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		121.0	mmHg	4.0	5.66	radiotelemetry	carotid artery			0				-	43542	421
SS-Hexim2em4Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	10	1/3 systolic pressure + 2/3 diastolic pressure		130.7	mmHg	3.58	11.32	radiotelemetry	carotid artery			0				-	43550	421
SS-Ulk3em4Mcwi-/+	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	4			10.01	mg/d	0.67	1.35	automated urine analysis				0				-	43562	421
SS-Sh2b3em1Mcwi-/-	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	16			10.41	mEq/d	0.37	1.48	automated urine analysis				0				-	43567	421
SS-Agtrapem4Mcwi-/-	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	6			10.07	mEq/d	0.86	2.12	automated urine analysis				0				-	43580	421
SS-Sh2b3em1Mcwi-/+	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	3			16.02	mg/d	3.39	5.88	automated urine analysis				0				-	43590	421
SS-Hexim2em4Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	1	1/3 systolic pressure + 2/3 diastolic pressure		154.0	mmHg			radiotelemetry	carotid artery			0				-	43622	421
SS-Wdr72em2Mcwi-/-	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	8			1.33	g	0.04	0.11	post excision weight measurement				0				-	43630	421
SS-Ulk3em4Mcwi-/-	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	18			1.4	g	0.03	0.12	post excision weight measurement				0				-	43637	421
SS-Adra2aem1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	8			363.75	beats/min	7.66	21.66	radiotelemetry	carotid artery			0				-	43659	421
SS-Sh2b3em1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	10			371.9	beats/min	5.06	16.01	radiotelemetry	carotid artery			0				-	43657	421
SS-Rasgrp3em1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	10			337.7	beats/min	15.82	50.04	radiotelemetry	carotid artery			0				-	43661	421
SS-Hexim2em4Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	1			344.0	beats/min			radiotelemetry	carotid artery			0				-	43666	421
SS-Agtrapem4Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	7			351.49	beats/min	6.29	16.65	radiotelemetry	carotid artery			0				-	43670	421
SS-Sh2b3em1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	12			373.58	beats/min	7.33	25.41	radiotelemetry	carotid artery			0				-	43673	421
SS-Wdr72em2Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	7			371.57	beats/min	10.47	27.7	radiotelemetry	carotid artery			0				-	43679	421
SS-Agtrapem4Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	6			354.24	beats/min	6.81	16.69	radiotelemetry	carotid artery			0				-	43686	421
SS.LEW-(D18Rat29-D18Rat55)/Ayd	heart left ventricle posterior wall thickness	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	heart left ventricle posterior wall thickness	male	77 days	11			0.18	mm	0.01	0.02	transthoracic echocardiography		0		0					65116	542
SS/Jr	heart left ventricle posterior wall thickness	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	heart left ventricle posterior wall thickness	male	77 days	40			0.19	mm	0.0	0.02	transthoracic echocardiography		0		0					65115	542
WKY/Bbb	diastolic blood pressure	controlled sodium content diet	Kreutz R, et al., Proc Natl Acad Sci U S A 1995 Sep 12;92(19):8778-82	arterial blood pressure trait	not specified	0 days	8			83.5	mmHg	0.92	2.6	radiotelemetry		0.0		0					67198	116
FHH-Procm1Mcwi	serum glucose level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood glucose amount	male	70 days-84 days	10			107.5	mg/dl	12.74	40.29	standard blood chemistry panel				0					62478	527
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi	serum glucose level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood glucose amount	female	70 days-84 days	7			181.0	mg/dl	8.21	21.71	standard blood chemistry panel				0					62479	527
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi	serum glucose level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood glucose amount	female	70 days-84 days	4			159.75	mg/dl	15.93	31.86	standard blood chemistry panel				0					62488	527
F344-Plcb3Tn(sb-T2/Bart3)2.69Mcwi	serum glucose level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood glucose amount	male	70 days-84 days	1			156.0	mg/dl			standard blood chemistry panel				0					62493	527
F344-DccTn(sb-T2/Bart3)2.205Mcwi	serum glucose level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood glucose amount	male	70 days-84 days	6			197.0	mg/dl	12.94	31.7	standard blood chemistry panel				0					62499	527
FHH-Adra1am1Mcwi	serum glucose level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood glucose amount	female	70 days-84 days	9			140.11	mg/dl	4.8	14.39	standard blood chemistry panel				0					62505	527
FHH-Tgfbr2m2Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	9			69.89	%	4.2	12.59	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62596	528
FHH-Ccr2m1Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	6			70.0	%	7.73	18.94	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62608	528
FHH-Htr1am1Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	18			55.72	%	4.55	19.31	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62619	528
FHH-F10m1Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	7			59.29	%	6.33	16.76	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62623	528
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	1			18.0	%			wire myography using a Digi-Med tissue force analysis system with force transducer				0					62626	528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	2			95.5	%	4.5	6.36	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62628	528
FHH/EurMcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	6			80.33	%	8.26	20.23	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62629	528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	2			26.5	%	13.5	19.09	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62632	528
BN-Lcatm3Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	3			43.0	%	17.62	30.51	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62631	528
FHH-Egln3m1Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	6			48.0	%	4.27	10.45	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62635	528
F344-DccTn(sb-T2/Bart3)2.205Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	7			61.71	%	6.29	16.65	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62634	528
FHH-Adipoqm3Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	5			52.8	%	11.24	25.14	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62637	528
FHH-Adra1am1Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	8			80.13	%	4.26	12.05	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62639	528
FHH-Adra1am1Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	8			73.75	%	5.49	15.53	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62641	528
FHH-Adipoqm1Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	10			0.01	umol/l	0.0	0.01	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62733	528
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	3			57.67	%	5.04	8.74	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62654	528
F344-Plce1Tn(sb-T2/Bart3)2.146Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	8			0.01	umol/l	0.0	0.01	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62741	528
FHH-Slc8a2m1Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	13			0.01	umol/l	0.0	0.01	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62744	528
FHH-Adipoqm1Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	8			0.01	umol/l	0.0	0.01	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62749	528
FHH-Procm1Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	8			0.06	umol/l	0.02	0.06	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62755	528
FHH-F10m2Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	17			0.01	umol/l	0.0	0.01	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62758	528
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	3			0.01	umol/l	0.0	0.0	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62772	528
FHH/EurMcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	6			0.01	umol/l	0.0	0.01	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62774	528
F344-AbatTn(sb-T2/Bart3)2.163Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	1			0.0	umol/l			wire myography using a Digi-Med tissue force analysis system with force transducer				0					62787	528
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	2			0.01	umol/l	0.0	0.0	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62791	528
FHH/EurMcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	119			0.01	umol/l	0.0	0.02	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62785	528
FHH-Slc8a2m1Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	15			0.02	umol/l	0.01	0.03	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62792	528
FHH-Tlr4m1Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	11			0.01	umol/l	0.0	0.01	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62793	528
FHH-Egln3m1Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	13			0.03	umol/l	0.01	0.04	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62795	528
SS-Ghsrm3Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (1 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	2			1.01	g/mg	0.2	0.28	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62808	528
SS-Klf4m3Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (1 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	9			1.57	g/mg	0.1	0.28	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62806	528
SS/JrHsdMcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (1 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	5			1.29	g/mg	0.11	0.24	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62809	528
SS-Sod3m1Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (1 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	12			1.33	g/mg	0.07	0.25	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62810	528
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	1			-6.97	null			wire myography using a Digi-Med tissue force analysis system with force transducer				0					62815	528
FHH-Adipoqm1Mcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	8			-6.94	null	0.16	0.45	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62828	528
FHH-Procm1Mcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	7			-6.98	null	0.12	0.31	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62833	528
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	4			-6.88	null	0.05	0.1	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62843	528
FHH-F10m1Mcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	7			-6.8	null	0.08	0.2	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62846	528
FHH-Egln3m1Mcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	13			-6.85	null	0.03	0.12	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62871	528
BN/NHsdMcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	8			-6.98	null	0.1	0.28	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62874	528
BN/NHsdMcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	5			-6.71	null	0.05	0.1	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62876	528
SS-Klf4m3Mcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (1 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	9			-6.67	null	0.08	0.25	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62882	528
SS-Cpt2m1Mcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (1 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	1			-5.74	null			wire myography using a Digi-Med tissue force analysis system with force transducer				0					62884	528
SS-Sod3m1Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (1 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	9			-8.11	null	0.07	0.2	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		62891	528
SS/JrHsdMcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (1 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	5			-7.82	null	0.1	0.23	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		62896	528
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Vascular data	body mass	male	70 days-84 days	1			277.0	g			whole body digital scale				0					62902	528
FHH-Tgfbr2m2Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Vascular data	body mass	male	70 days-84 days	10			274.4	g	6.51	20.58	whole body digital scale				0					62901	528
FHH-Nr0b2m1Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Vascular data	body mass	male	70 days-84 days	4			269.0	g	5.74	11.49	whole body digital scale				0					62913	528
FHH-Ccr2m1Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Vascular data	body mass	female	70 days-84 days	7			183.71	g	2.49	6.6	whole body digital scale				0					62918	528
FHH-Procm1Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Vascular data	body mass	female	70 days-84 days	8			215.38	g	11.16	31.57	whole body digital scale				0					62921	528
FHH-Nr4a1m1Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Vascular data	body mass	male	70 days-84 days	6			250.67	g	8.61	21.09	whole body digital scale				0					62927	528
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Vascular data	body mass	female	70 days-84 days	8			172.88	g	4.25	12.02	whole body digital scale				0					62929	528
FHH-Nr4a1m1Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Vascular data	body mass	female	70 days-84 days	6			182.67	g	3.18	7.79	whole body digital scale				0					62935	528
FHH-Ghsrm1Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Vascular data	body mass	male	70 days-84 days	5			267.0	g	19.31	43.19	whole body digital scale				0					62946	528
FHH-Adipoqm3Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Vascular data	body mass	male	70 days-84 days	5			267.4	g	14.57	32.59	whole body digital scale				0					62950	528
BN/NHsdMcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Vascular data	body mass	female	70 days-84 days	5			148.8	g	1.85	4.15	whole body digital scale				0					62966	528
SS-Ghsrm3Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (1 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	2			46.0	%	1.0	1.41	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62985	528
F344-Elmod3Tn(sb-T2/Bart3)2.42Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	6			1.61	E-7mole	0.29	0.72	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62994	528
F344-Elmod3Tn(sb-T2/Bart3)2.42Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	2			0.96	E-7mole	0.22	0.32	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63001	528
FHH-Adipoqm2Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	8			0.81	E-7mole	0.15	0.42	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63007	528
F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	1			1.2	E-7mole			wire myography using a Digi-Med tissue force analysis system with force transducer				0					63014	528
FHH-F10m2Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	11			2.37	E-7mole	0.46	1.54	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63022	528
F344-Plcb3Tn(sb-T2/Bart3)2.69Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	1			2.84	E-7mole			wire myography using a Digi-Med tissue force analysis system with force transducer				0					63030	528
F344-Nrg1Tn(sb-T2/Bart3)2.183Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	5			1.6	E-7mole	0.37	0.82	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63052	528
FHH-Chr 2BN/Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	9			1.37	g/mg	0.26	0.78	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	57312	522
SS-Chr 9BN/Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	10			1.53	g/mg	0.18	0.56	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	57317	522
FHH-Chr 6BN/Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	9			1.37	g/mg	0.19	0.57	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	57319	522
FHH-Chr 2BN/Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	9			0.73	g/mg	0.09	0.27	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	57328	522
FHH-Chr XBN/Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	10			1.0	g/mg	0.16	0.51	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	57343	522
SS-Chr 4BN/Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	8			0.71	g/mg	0.09	0.24	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	57379	522
SS/JrHsdMcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	90			1.09	g/mg	0.06	0.56	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	57374	522
FHH/EurMcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	7			-7.09	null	0.15	0.41	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	57409	522
WKY/NCrl	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	14			0.05	umol/l	0.01	0.03	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	57425	522
LEW/Crl	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	24			0.05	umol/l	0.01	0.03	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	57431	522
F344/DuCrl	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	20			0.04	umol/l	0.01	0.02	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	57428	522
SS-Chr 15BN/Mcwi	body weight	controlled sodium content diet (4 %) (for 21 days)	PhysGen Vascular data	body mass	female	70 days-84 days	10			215.0	g	4.2	13.3	whole body digital scale				0				Moms and pups used in studies were fed Teklad	55199	522
SS-Chr 13BN/Mcwi	body weight	controlled sodium content diet (4 %) (for 21 days)	PhysGen Vascular data	body mass	female	70 days-84 days	16			215.8	g	4.0	15.8	whole body digital scale				0				Moms and pups used in studies were fed Teklad	55205	522
FHH-Chr 20BN/Mcwi	body weight	controlled sodium content diet (4 %) (for 21 days)	PhysGen Vascular data	body mass	male	70 days-84 days	10			270.3	g	3.4	10.8	whole body digital scale				0				Moms and pups used in studies were fed Teklad	55207	522
FHH-Chr 8BN/Mcwi	body weight	controlled sodium content diet (4 %) (for 21 days)	PhysGen Vascular data	body mass	male	70 days-84 days	10			267.6	g	7.8	24.8	whole body digital scale				0				Moms and pups used in studies were fed Teklad	55203	522
FHH-Chr YBN/Mcwi	body weight	controlled sodium content diet (4 %) (for 21 days)	PhysGen Vascular data	body mass	male	70 days-84 days	11			217.6	g	13.3	44.2	whole body digital scale				0				Moms and pups used in studies were fed Teklad	55215	522
FHH/EurMcwi	body weight	controlled sodium content diet (4 %) (for 21 days)	PhysGen Vascular data	body mass	male	70 days-84 days	51			234.9	g	4.6	33.1	whole body digital scale				0				Moms and pups used in studies were fed Teklad	55212	522
SS-Chr 18BN/Mcwi	body weight	controlled sodium content diet (4 %) (for 21 days)	PhysGen Vascular data	body mass	male	70 days-84 days	21			329.5	g	4.6	21.0	whole body digital scale				0				Moms and pups used in studies were fed Teklad	55218	522
SS-Chr YBN/Mcwi	body weight	controlled sodium content diet (4 %) (for 21 days)	PhysGen Vascular data	body mass	male	70 days-84 days	20			300.3	g	5.9	26.4	whole body digital scale				0				Moms and pups used in studies were fed Teklad	55216	522
FHH-Chr 4BN/Mcwi	body weight	controlled sodium content diet (4 %) (for 21 days)	PhysGen Vascular data	body mass	male	70 days-84 days	10			227.4	g	3.1	9.7	whole body digital scale				0				Moms and pups used in studies were fed Teklad	55223	522
SS-Chr 19BN/Mcwi	body weight	controlled sodium content diet (4 %) (for 21 days)	PhysGen Vascular data	body mass	male	70 days-84 days	10			305.6	g	9.2	29.1	whole body digital scale				0				Moms and pups used in studies were fed Teklad	55229	522
FHH-Chr 7BN/Mcwi	body weight	controlled sodium content diet (4 %) (for 21 days)	PhysGen Vascular data	body mass	male	70 days-84 days	9			252.3	g	5.3	16.0	whole body digital scale				0				Moms and pups used in studies were fed Teklad	55242	522
Hsd:SD	logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	16			-7.49	null	0.05	0.22	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	55247	522
LEW/Crl	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	24			73.54	%	3.22	15.75	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	55383	522
LE/BluGill	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	14			62.79	%	2.82	10.56	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	55387	522
BN/NHsdMcwi	red blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	female	70 days-84 days	27			8.12	x 10E6 cells/ul	0.07	0.36	automated blood cell counting method				0					60610	527
SS-Sod3m1Mcwi	serum glucose level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood glucose amount	female	70 days-84 days	11			140.36	mg/dl	16.35	54.22	standard blood chemistry panel				0					60622	527
F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi	hematocrit	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	female	70 days-84 days	1			42.8	%			automated blood cell counting method				0					60651	527
F344/NHsd	hematocrit	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	female	70 days-84 days	4			46.38	%	2.8	5.61	automated blood cell counting method				0					60658	527
F344-Inpp4bTn(sb-T2/Bart3)2.143Mcwi	hematocrit	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	male	70 days-84 days	7			45.83	%	0.95	2.51	automated blood cell counting method				0					60689	527
FHH-Nr0b2m1Mcwi	mean corpuscular volume	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte size trait	male	70 days-84 days	10			52.07	fl	0.22	0.7	automated blood cell counting method				0					60751	527
FHH-F10m1Mcwi	mean corpuscular volume	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte size trait	female	70 days-84 days	11			53.67	fl	0.49	1.64	automated blood cell counting method				0					60757	527
FHH-F10m1Mcwi	mean corpuscular volume	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte size trait	male	70 days-84 days	10			51.48	fl	0.31	0.97	automated blood cell counting method				0					60772	527
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi	mean corpuscular volume	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte size trait	male	70 days-84 days	2			53.85	fl	0.35	0.5	automated blood cell counting method				0					60769	527
BN-Lcatm3Mcwi	mean corpuscular volume	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte size trait	male	70 days-84 days	1			53.0	fl			automated blood cell counting method				0					60783	527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi	mean corpuscular volume	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte size trait	female	70 days-84 days	2			55.8	fl	0.0	0.0	automated blood cell counting method				0					60782	527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi	mean corpuscular volume	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte size trait	female	70 days-84 days	4			55.7	fl	0.27	0.54	automated blood cell counting method				0					60792	527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi	mean corpuscular volume	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte size trait	male	70 days-84 days	3			53.27	fl	0.23	0.4	automated blood cell counting method				0					60795	527
SS-Klf4m3Mcwi	serum bicarbonate level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bicarbonate amount	male	70 days-84 days	8			18.5	mmol/l	0.5	1.41	standard blood chemistry panel				0					60812	527
SS-Chr 18BN/Mcwi	logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	10			-8.31	null	0.08	0.24	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	55483	522
SS-Chr 16BN/Mcwi	logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	10			-8.43	null	0.1	0.3	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	55486	522
SS-Chr 16BN/Mcwi	logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	10			-8.36	null	0.11	0.33	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	55490	522
Hsd:SD	concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	16			0.33	10E-7mol/l	0.05	0.19	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	55502	522
BN-Tgfbr2m1Mcwi	blood neutrophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	neutrophil quantity	female	70 days-84 days	3			1.26	x 1000 cells/ul	0.26	0.46	automated blood cell counting method				0					60833	527
FHH-Tgfbr2m2Mcwi	blood neutrophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	neutrophil quantity	female	70 days-84 days	14			0.88	x 1000 cells/ul	0.08	0.29	automated blood cell counting method				0					60836	527
F344-Plce1Tn(sb-T2/Bart3)2.146Mcwi	blood neutrophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	neutrophil quantity	male	70 days-84 days	6			1.23	x 1000 cells/ul	0.26	0.64	automated blood cell counting method				0					60837	527
FHH-Lcatm1Mcwi	blood neutrophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	neutrophil quantity	female	70 days-84 days	15			0.73	x 1000 cells/ul	0.12	0.46	automated blood cell counting method				0					60839	527
FHH-Ccr2m1Mcwi	blood neutrophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	neutrophil quantity	female	70 days-84 days	5			0.58	x 1000 cells/ul	0.23	0.51	automated blood cell counting method				0					60848	527
FHH-Procm1Mcwi	blood neutrophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	neutrophil quantity	female	70 days-84 days	8			0.73	x 1000 cells/ul	0.2	0.56	automated blood cell counting method				0					60851	527
FHH-Procm1Mcwi	blood neutrophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	neutrophil quantity	male	70 days-84 days	9			1.07	x 1000 cells/ul	0.39	1.18	automated blood cell counting method				0					60858	527
FHH-F10m1Mcwi	blood neutrophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	neutrophil quantity	male	70 days-84 days	10			0.76	x 1000 cells/ul	0.1	0.32	automated blood cell counting method				0					60864	527
FHH-Adipoqm3Mcwi	blood neutrophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	neutrophil quantity	female	70 days-84 days	6			0.54	x 1000 cells/ul	0.16	0.4	automated blood cell counting method				0					60880	527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi	blood neutrophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	neutrophil quantity	female	70 days-84 days	4			0.9	x 1000 cells/ul	0.04	0.07	automated blood cell counting method				0					60884	527
SS-Sod3m1Mcwi	serum sodium level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	male	70 days-84 days	10			141.2	mmol/l	1.18	3.74	flame atomic emission spectrometry				0					60902	527
SS-Cpt2m1Mcwi	serum sodium level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	female	70 days-84 days	1			146.0	mmol/l			flame atomic emission spectrometry				0					60905	527
FHH-Adipoqm2Mcwi	serum globulin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood globulin amount	female	70 days-84 days	12			1.51	g/dl	0.06	0.19	standard blood chemistry panel				0			replaced obsolete serum globulin level term, 1/19/2016		60911	527
FHH-Agtr1bm1Mcwi	serum globulin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood globulin amount	female	70 days-84 days	14			1.51	g/dl	0.04	0.15	standard blood chemistry panel				0			replaced obsolete serum globulin level term, 1/19/2016		60924	527
FHH-Nr4a1m1Mcwi	serum globulin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood globulin amount	male	70 days-84 days	11			1.77	g/dl	0.05	0.17	standard blood chemistry panel				0			replaced obsolete serum globulin level term, 1/19/2016		60939	527
FHH-Htr1am1Mcwi	serum globulin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood globulin amount	male	70 days-84 days	20			1.75	g/dl	0.03	0.14	standard blood chemistry panel				0			replaced obsolete serum globulin level term, 1/19/2016		60942	527
FHH-Nr4a1m1Mcwi	serum globulin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood globulin amount	female	70 days-84 days	11			1.58	g/dl	0.06	0.21	standard blood chemistry panel				0			replaced obsolete serum globulin level term, 1/19/2016		60947	527
F344-DccTn(sb-T2/Bart3)2.205Mcwi	serum globulin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood globulin amount	female	70 days-84 days	4			1.9	g/dl	0.04	0.08	standard blood chemistry panel				0			replaced obsolete serum globulin level term, 1/19/2016		60948	527
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi	serum globulin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood globulin amount	male	70 days-84 days	1			2.4	g/dl			standard blood chemistry panel				0			replaced obsolete serum globulin level term, 1/19/2016		60949	527
BN-Lcatm3Mcwi	serum globulin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood globulin amount	female	70 days-84 days	2			1.75	g/dl	0.05	0.07	standard blood chemistry panel				0			replaced obsolete serum globulin level term, 1/19/2016		60954	527
FHH-Egln3m1Mcwi	serum globulin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood globulin amount	male	70 days-84 days	6			1.78	g/dl	0.06	0.15	standard blood chemistry panel				0			replaced obsolete serum globulin level term, 1/19/2016		60960	527
FHH-Tlr4m1Mcwi	serum globulin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood globulin amount	female	70 days-84 days	9			1.54	g/dl	0.07	0.2	standard blood chemistry panel				0			replaced obsolete serum globulin level term, 1/19/2016		60972	527
F344-Nrg1Tn(sb-T2/Bart3)2.183Mcwi	serum globulin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood globulin amount	female	70 days-84 days	5			1.9	g/dl	0.07	0.16	standard blood chemistry panel				0			replaced obsolete serum globulin level term, 1/19/2016		60976	527
SS-Ghsrm3Mcwi	hematocrit	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	male	70 days-84 days	2			50.3	%	1.4	1.98	automated blood cell counting method				0					60981	527
SS-Sod3m1Mcwi	hematocrit	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	male	70 days-84 days	10			48.01	%	1.22	3.85	automated blood cell counting method				0					60984	527
SS-Klf4m3Mcwi	hematocrit	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	female	70 days-84 days	7			46.94	%	1.27	3.35	automated blood cell counting method				0					60985	527
SS-Ghsrm3Mcwi	hematocrit	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	female	70 days-84 days	1			48.8	%			automated blood cell counting method				0					60988	527
SS/JrHsdMcwi	hematocrit	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	female	70 days-84 days	17			46.26	%	0.61	2.53	automated blood cell counting method				0					60989	527
FHH-Adipoqm2Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours)	PhysGen Biochemistry data	blood creatinine amount	female	70 days-84 days	12			0.28	mg/dl	0.04	0.15	automated plasma creatinine analysis				0					60993	527
FHH-Lcatm1Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours)	PhysGen Biochemistry data	blood creatinine amount	male	70 days-84 days	13			0.31	mg/dl	0.05	0.17	automated plasma creatinine analysis				0					60996	527
FHH-Slc8a2m1Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours)	PhysGen Biochemistry data	blood creatinine amount	female	70 days-84 days	12			0.23	mg/dl	0.03	0.09	automated plasma creatinine analysis				0					61004	527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours)	PhysGen Biochemistry data	blood creatinine amount	female	70 days-84 days	2			0.3	mg/dl	0.1	0.14	automated plasma creatinine analysis				0					61002	527
BN-Tgfbr2m1Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours)	PhysGen Biochemistry data	blood creatinine amount	male	70 days-84 days	7			0.3	mg/dl	0.03	0.08	automated plasma creatinine analysis				0					61008	527
SS/JrHsdMcwi	sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	blood vessel smooth muscle dilation trait	male	70 days-84 days	12			99.42	%	0.26	0.9	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	55715	522
Hsd:SD	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	10			69.0	%	6.69	21.17	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	55730	522
Hsd:SD	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	14			85.5	%	4.86	18.18	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	55731	522
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours)	PhysGen Biochemistry data	blood creatinine amount	female	70 days-84 days	7			0.34	mg/dl	0.04	0.1	automated plasma creatinine analysis				0					61023	527
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours)	PhysGen Biochemistry data	blood creatinine amount	female	70 days-84 days	4			0.43	mg/dl	0.05	0.1	automated plasma creatinine analysis				0					61032	527
FHH-Egln3m1Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours)	PhysGen Biochemistry data	blood creatinine amount	male	70 days-84 days	6			0.2	mg/dl	0.0	0.0	automated plasma creatinine analysis				0					61042	527
F344-DccTn(sb-T2/Bart3)2.205Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours)	PhysGen Biochemistry data	blood creatinine amount	male	70 days-84 days	6			0.33	mg/dl	0.03	0.08	automated plasma creatinine analysis				0					61043	527
FHH-Adipoqm1Mcwi	plasma anion gap	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	ion homeostasis trait	female	70 days-84 days	9			25.22	mmol/l	1.35	4.06	standard blood chemistry panel				0					61064	527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi	plasma anion gap	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	ion homeostasis trait	male	70 days-84 days	1			29.0	mmol/l			standard blood chemistry panel				0					61067	527
FHH-Tgfbr2m2Mcwi	plasma anion gap	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	ion homeostasis trait	female	70 days-84 days	10			24.4	mmol/l	1.19	3.78	standard blood chemistry panel				0					61072	527
F344/NHsd	plasma anion gap	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	ion homeostasis trait	male	70 days-84 days	7			24.29	mmol/l	1.19	3.15	standard blood chemistry panel				0					61089	527
FHH-Nr4a1m1Mcwi	plasma anion gap	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	ion homeostasis trait	male	70 days-84 days	11			26.27	mmol/l	1.06	3.52	standard blood chemistry panel				0					61093	527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi	plasma anion gap	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	ion homeostasis trait	male	70 days-84 days	7			25.14	mmol/l	0.91	2.41	standard blood chemistry panel				0					61106	527
FHH-Egln3m1Mcwi	plasma anion gap	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	ion homeostasis trait	male	70 days-84 days	6			22.33	mmol/l	0.49	1.21	standard blood chemistry panel				0					61114	527
FHH-Adipoqm3Mcwi	plasma anion gap	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	ion homeostasis trait	male	70 days-84 days	5			24.2	mmol/l	1.69	3.77	standard blood chemistry panel				0					61117	527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi	plasma anion gap	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	ion homeostasis trait	female	70 days-84 days	2			26.0	mmol/l	1.0	1.41	standard blood chemistry panel				0					61120	527
FHH-Adipoqm3Mcwi	plasma anion gap	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	ion homeostasis trait	female	70 days-84 days	6			21.33	mmol/l	0.95	2.34	standard blood chemistry panel				0					61116	527
FHH-Tgfbr2m2Mcwi	mean corpuscular hemoglobin concentration	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	14			33.29	g/dl	0.24	0.88	automated blood cell counting method				0					61144	527
FHH-Agtr1bm1Mcwi	mean corpuscular hemoglobin concentration	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	15			33.93	g/dl	0.12	0.45	automated blood cell counting method				0					61143	527
FHH-Lcatm1Mcwi	mean corpuscular hemoglobin concentration	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	15			33.6	g/dl	0.14	0.54	automated blood cell counting method				0					61147	527
FHH-Agtr1bm1Mcwi	mean corpuscular hemoglobin concentration	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	14			33.34	g/dl	0.11	0.41	automated blood cell counting method				0					61150	527
FHH-Nr0b2m1Mcwi	mean corpuscular hemoglobin concentration	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	10			33.64	g/dl	0.21	0.67	automated blood cell counting method				0					61151	527
BN-Tgfbr2m1Mcwi	mean corpuscular hemoglobin concentration	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	7			33.5	g/dl	0.14	0.37	automated blood cell counting method				0					61152	527
FHH-F10m1Mcwi	mean corpuscular hemoglobin concentration	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	10			33.45	g/dl	0.14	0.45	automated blood cell counting method				0					61172	527
F344-DccTn(sb-T2/Bart3)2.205Mcwi	mean corpuscular hemoglobin concentration	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	4			32.73	g/dl	0.62	1.24	automated blood cell counting method				0					61174	527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi	mean corpuscular hemoglobin concentration	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	7			32.34	g/dl	0.17	0.45	automated blood cell counting method				0					61178	527
FHH-Adra1am1Mcwi	mean corpuscular hemoglobin concentration	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	8			33.48	g/dl	0.17	0.48	automated blood cell counting method				0					61191	527
FHH-Egln3m1Mcwi	mean corpuscular hemoglobin concentration	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	14			32.45	g/dl	0.14	0.53	automated blood cell counting method				0					61200	527
SS/JrHsdMcwi	serum aspartate aminotransferase activity level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood aspartate transaminase amount	female	70 days-84 days	16			174.31	U/l	12.33	49.32	standard blood chemistry panel				0					61215	527
F344-Elmod3Tn(sb-T2/Bart3)2.42Mcwi	serum total protein level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood total protein amount	male	70 days-84 days	5			6.12	g/dl	0.04	0.08	standard blood chemistry panel				0					61224	527
WKY/NCrl	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	12			0.55	E-7mole	0.13	0.44	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	55978	522
F344/DuCrl	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	13			1.8	E-7mole	0.32	1.14	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	55981	522
LEW/Crl	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	24			1.43	E-7mole	0.27	1.32	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	55984	522
SS-Chr 16BN/Mcwi	logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	5			-8.5	null	0.17	0.39	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	56011	522
FHH-Nr0b2m1Mcwi	serum total protein level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood total protein amount	male	70 days-84 days	10			5.18	g/dl	0.06	0.19	standard blood chemistry panel				0					61233	527
FHH-Procm1Mcwi	serum total protein level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood total protein amount	female	70 days-84 days	8			5.24	g/dl	0.15	0.42	standard blood chemistry panel				0					61241	527
F344-Plce1Tn(sb-T2/Bart3)2.146Mcwi	serum total protein level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood total protein amount	female	70 days-84 days	5			5.84	g/dl	0.17	0.37	standard blood chemistry panel				0					61236	527
FHH-Ccr2m1Mcwi	serum total protein level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood total protein amount	male	70 days-84 days	8			5.44	g/dl	0.05	0.13	standard blood chemistry panel				0					61246	527
F344/NHsd	serum total protein level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood total protein amount	female	70 days-84 days	4			5.0	g/dl	0.25	0.5	standard blood chemistry panel				0					61252	527
FHH-Nr4a1m1Mcwi	serum total protein level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood total protein amount	female	70 days-84 days	11			5.36	g/dl	0.09	0.31	standard blood chemistry panel				0					61255	527
F344-Plcb3Tn(sb-T2/Bart3)2.69Mcwi	serum total protein level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood total protein amount	male	70 days-84 days	1			5.1	g/dl			standard blood chemistry panel				0					61263	527
FHH/EurMcwi	serum total protein level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood total protein amount	male	70 days-84 days	159			5.56	g/dl	0.02	0.28	standard blood chemistry panel				0					61272	527
FHH-Adipoqm1Mcwi	serum potassium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	female	70 days-84 days	9			4.97	mmol/l	0.14	0.43	flame atomic emission spectrometry				0					61290	527
FHH-Lcatm1Mcwi	serum potassium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	male	70 days-84 days	12			5.74	mmol/l	0.55	1.9	flame atomic emission spectrometry				0					61294	527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi	serum potassium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	male	70 days-84 days	1			3.4	mmol/l			flame atomic emission spectrometry				0					61293	527
F344-Plce1Tn(sb-T2/Bart3)2.146Mcwi	serum potassium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	male	70 days-84 days	6			4.23	mmol/l	0.4	0.97	flame atomic emission spectrometry				0					61299	527
F344-Elmod3Tn(sb-T2/Bart3)2.42Mcwi	serum potassium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	female	70 days-84 days	3			4.67	mmol/l	0.19	0.32	flame atomic emission spectrometry				0					61303	527
FHH-Agtr1bm1Mcwi	serum potassium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	female	70 days-84 days	14			4.05	mmol/l	0.13	0.47	flame atomic emission spectrometry				0					61304	527
FHH-Nr0b2m1Mcwi	serum potassium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	male	70 days-84 days	10			4.76	mmol/l	0.24	0.75	flame atomic emission spectrometry				0					61305	527
FHH-Adipoqm1Mcwi	serum potassium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	male	70 days-84 days	8			5.99	mmol/l	0.53	1.51	flame atomic emission spectrometry				0					61307	527
FHH-Htr1am1Mcwi	serum potassium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	male	70 days-84 days	19			5.08	mmol/l	0.16	0.71	flame atomic emission spectrometry				0					61322	527
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi	serum potassium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	female	70 days-84 days	4			4.2	mmol/l	0.32	0.65	flame atomic emission spectrometry				0					61330	527
FHH-Ghsrm1Mcwi	serum potassium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	female	70 days-84 days	9			4.28	mmol/l	0.11	0.33	flame atomic emission spectrometry				0					61331	527
FHH-Ghsrm1Mcwi	serum potassium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	male	70 days-84 days	15			5.35	mmol/l	0.29	1.11	flame atomic emission spectrometry				0					61339	527
FHH-Adra1am1Mcwi	serum potassium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	female	70 days-84 days	9			4.91	mmol/l	0.34	1.02	flame atomic emission spectrometry				0					61347	527
BN/NHsdMcwi	serum potassium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	female	70 days-84 days	27			4.18	mmol/l	0.09	0.45	flame atomic emission spectrometry				0					61358	527
FHH-Adipoqm1Mcwi	total white blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	leukocyte quantity	female	70 days-84 days	9			3.88	x 1000 cells/ul	0.41	1.23	automated blood cell counting method				0					61362	527
FHH-Lcatm1Mcwi	total white blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	leukocyte quantity	male	70 days-84 days	13			4.78	x 1000 cells/ul	0.38	1.39	automated blood cell counting method				0					61366	527
FHH-Slc8a2m1Mcwi	total white blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	leukocyte quantity	female	70 days-84 days	11			3.53	x 1000 cells/ul	0.34	1.12	automated blood cell counting method				0					61374	527
BN-Tgfbr2m1Mcwi	total white blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	leukocyte quantity	male	70 days-84 days	7			7.44	x 1000 cells/ul	0.5	1.33	automated blood cell counting method				0					61378	527
FHH-Adipoqm2Mcwi	total white blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	leukocyte quantity	male	70 days-84 days	5			4.64	x 1000 cells/ul	0.61	1.36	automated blood cell counting method				0					61381	527
FHH-F10m1Mcwi	total white blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	leukocyte quantity	female	70 days-84 days	11			4.25	x 1000 cells/ul	0.66	2.18	automated blood cell counting method				0					61383	527
F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi	total white blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	leukocyte quantity	female	70 days-84 days	1			4.7	x 1000 cells/ul			automated blood cell counting method				0					61389	527
F344/NHsd	total white blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	leukocyte quantity	female	70 days-84 days	4			4.18	x 1000 cells/ul	0.6	1.2	automated blood cell counting method				0					61396	527
FHH/EurMcwi	total white blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	leukocyte quantity	female	70 days-84 days	25			5.01	x 1000 cells/ul	0.3	1.48	automated blood cell counting method				0					61405	527
FHH/EurMcwi	total white blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	leukocyte quantity	male	70 days-84 days	157			5.08	x 1000 cells/ul	0.19	2.33	automated blood cell counting method				0					61416	527
FHH-Slc8a2m1Mcwi	total white blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	leukocyte quantity	male	70 days-84 days	8			3.96	x 1000 cells/ul	0.53	1.5	automated blood cell counting method				0					61423	527
SS/JrHsdMcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	13			1.27	E-7mole	0.38	1.36	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	54596	522
SHR/NCrl	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	10			0.71	E-7mole	0.1	0.31	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	54597	522
Hsd:SD	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	13			40.71	%	5.21	18.79	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	54636	522
SS.BN-(D12Arb13-D12Rat79)/Mcwi	logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	14			-8.48	null	0.05	0.18	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56018	522
SS-Chr 18BN/Mcwi	logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	9			-8.05	null	0.09	0.27	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56034	522
LEW/Crl	body weight	controlled sodium content diet (4 %) (for 21 days)	PhysGen Vascular data	body mass	female	70 days-84 days	25			210.8	g	1.7	8.6	whole body digital scale				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56069	522
Crl:CD(SD)	body weight	controlled sodium content diet (4 %) (for 21 days)	PhysGen Vascular data	body mass	female	70 days-84 days	10			264.9	g	7.0	22.2	whole body digital scale				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56072	522
F344/DuCrl	body weight	controlled sodium content diet (4 %) (for 21 days)	PhysGen Vascular data	body mass	female	70 days-84 days	20			155.9	g	3.1	13.7	whole body digital scale				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56076	522
FHH-Chr 12BN/Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	12			-8.28	null	0.21	0.74	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter	Moms and pups used in studies were fed Teklad	56079	522
SS-Chr 10BN/Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	10			-7.78	null	0.08	0.27	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter	Moms and pups used in studies were fed Teklad	56080	522
SS-Chr 6BN/Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	21			-7.68	null	0.11	0.48	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter	Moms and pups used in studies were fed Teklad	56094	522
SS-Chr 10BN/Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	9			-8.06	null	0.05	0.14	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter	Moms and pups used in studies were fed Teklad	56096	522
FHH-Chr XBN/Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	10			-7.8	null	0.09	0.28	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter	Moms and pups used in studies were fed Teklad	56111	522
FHH-Chr 3BN/Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	10			-8.16	null	0.06	0.18	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter	Moms and pups used in studies were fed Teklad	56121	522
FHH-Chr 19BN/Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	10			-8.23	null	0.06	0.2	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter	Moms and pups used in studies were fed Teklad	56125	522
SS-Chr 18BN/Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	21			-8.22	null	0.14	0.64	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter	Moms and pups used in studies were fed Teklad	56144	522
SS-Chr XBN/Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	10			-8.24	null	0.11	0.35	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter	Moms and pups used in studies were fed Teklad	56146	522
SS-Chr 12BN/Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	10			-7.27	null	0.06	0.18	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter	Moms and pups used in studies were fed Teklad	56156	522
SS.BN-(D8Rat163-D8Rat81)/Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	8			-8.04	null	0.09	0.25	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter	Moms and pups used in studies were fed Teklad	56163	522
FHH-Chr 7BN/Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	9			-8.26	null	0.07	0.21	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter	Moms and pups used in studies were fed Teklad	56160	522
BN/NHsdMcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	20			-6.8	null	0.1	0.44	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter	Moms and pups used in studies were fed Teklad	56165	522
SS/JrHsdMcwi	sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	20			99.85	%	0.11	0.49	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	56201	522
BN/NHsdMcwi	blood eosinophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	eosinophil quantity	male	70 days-84 days	43			0.12	x 1000 cells/ul	0.02	0.13	automated blood cell counting method				0					62269	527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi	blood eosinophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	eosinophil quantity	female	70 days-84 days	2			0.03	x 1000 cells/ul	0.03	0.04	automated blood cell counting method				0					62265	527
F344-Inpp4bTn(sb-T2/Bart3)2.143Mcwi	blood eosinophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	eosinophil quantity	male	70 days-84 days	7			0.08	x 1000 cells/ul	0.02	0.06	automated blood cell counting method				0					62267	527
FHH-Nr0b2m1Mcwi	serum chloride level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood chloride amount	female	70 days-84 days	6			103.17	mmol/l	1.51	3.71	standard blood chemistry panel				0					62283	527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi	serum chloride level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood chloride amount	male	70 days-84 days	1			99.0	mmol/l			standard blood chemistry panel				0					62287	527
F344-Plce1Tn(sb-T2/Bart3)2.146Mcwi	serum chloride level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood chloride amount	male	70 days-84 days	6			99.17	mmol/l	0.6	1.47	standard blood chemistry panel				0					62293	527
FHH-Agtr1bm1Mcwi	serum chloride level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood chloride amount	female	70 days-84 days	14			104.71	mmol/l	0.46	1.73	standard blood chemistry panel				0					62298	527
FHH-Htr1am1Mcwi	serum chloride level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood chloride amount	female	70 days-84 days	13			105.15	mmol/l	0.78	2.82	standard blood chemistry panel				0					62308	527
FHH-F10m2Mcwi	serum chloride level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood chloride amount	male	70 days-84 days	16			104.44	mmol/l	0.63	2.53	standard blood chemistry panel				0					62310	527
FHH-F10m1Mcwi	serum chloride level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood chloride amount	male	70 days-84 days	10			103.7	mmol/l	0.78	2.45	standard blood chemistry panel				0					62320	527
FHH-Ghsrm1Mcwi	serum chloride level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood chloride amount	male	70 days-84 days	15			104.73	mmol/l	0.74	2.87	standard blood chemistry panel				0					62333	527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi	serum chloride level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood chloride amount	female	70 days-84 days	4			101.75	mmol/l	1.18	2.36	standard blood chemistry panel				0					62340	527
FHH-Tlr4m1Mcwi	serum chloride level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood chloride amount	female	70 days-84 days	9			102.89	mmol/l	0.26	0.78	standard blood chemistry panel				0					62346	527
F344-Inpp4bTn(sb-T2/Bart3)2.143Mcwi	serum chloride level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood chloride amount	male	70 days-84 days	7			99.86	mmol/l	1.42	3.76	standard blood chemistry panel				0					62349	527
BN/NHsdMcwi	serum chloride level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood chloride amount	male	70 days-84 days	44			103.82	mmol/l	0.5	3.34	standard blood chemistry panel				0					62351	527
FHH-F10m2Mcwi	serum total cholesterol level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood cholesterol amount	male	70 days-84 days	16			60.19	mg/dl	1.95	7.78	standard blood chemistry panel				0					62382	527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi	serum total cholesterol level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood cholesterol amount	male	70 days-84 days	7			67.0	mg/dl	2.28	6.03	standard blood chemistry panel				0					62398	527
FHH/EurMcwi	serum total cholesterol level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood cholesterol amount	female	70 days-84 days	25			63.04	mg/dl	1.84	9.19	standard blood chemistry panel				0					62399	527
SS-Ghsrm3Mcwi	serum total protein level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood total protein amount	male	70 days-84 days	2			6.1	g/dl	0.3	0.42	standard blood chemistry panel				0					62437	527
FHH-Nr0b2m1Mcwi	serum glucose level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood glucose amount	female	70 days-84 days	6			178.5	mg/dl	6.69	16.39	standard blood chemistry panel				0					62447	527
FHH-Tgfbr2m2Mcwi	serum glucose level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood glucose amount	male	70 days-84 days	13			131.46	mg/dl	11.6	41.83	standard blood chemistry panel				0					62450	527
FHH-Lcatm1Mcwi	serum glucose level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood glucose amount	female	70 days-84 days	15			146.13	mg/dl	4.61	17.86	standard blood chemistry panel				0					62459	527
FHH-Tgfbr2m2Mcwi	serum glucose level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood glucose amount	female	70 days-84 days	14			137.43	mg/dl	7.74	28.95	standard blood chemistry panel				0					62456	527
FHH-Adipoqm2Mcwi	serum glucose level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood glucose amount	male	70 days-84 days	7			109.0	mg/dl	12.47	32.99	standard blood chemistry panel				0					62467	527
FHH-Chr 10BN/Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	10			73.5	%	4.84	15.31	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54776	522
GH/OmrMcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	3			54.33	%	4.33	7.51	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54784	522
FHH-Chr XBN/Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	10			92.3	%	3.45	10.92	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54789	522
FHH-Chr 16BN/Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	10			66.1	%	4.51	14.26	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54790	522
SS-Chr 15BN/Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	8			73.63	%	6.48	18.32	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54797	522
SS-Chr 13BN/Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	14			89.5	%	2.32	8.7	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54805	522
FHH-Chr 20BN/Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	10			85.9	%	4.5	14.22	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54807	522
SS-Chr 18BN/Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	20			63.05	%	4.72	21.12	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54819	522
SS-Chr 18BN/Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	18			67.11	%	4.57	19.37	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54823	522
FHH-Chr 4BN/Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	9			78.0	%	4.57	13.7	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54828	522
SS-Chr 19BN/Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	9			81.89	%	7.49	22.47	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54834	522
SS/JrHsdMcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	12			50.42	%	4.9	16.97	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	54856	522
FHH-Chr 7BN/Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	9			82.44	%	6.48	19.45	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54843	522
SS-Chr 16BN/Mcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	3			39.67	%	2.19	3.79	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	54854	522
FHH-Chr 6BN/Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	9			0.01	umol/l	0.0	0.01	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54887	522
FHH-Chr 2BN/Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	9			0.02	umol/l	0.01	0.02	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54884	522
SS-Chr 5BN/Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	9			0.02	umol/l	0.0	0.01	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54908	522
SS-Chr 16BN/Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	15			0.03	umol/l	0.01	0.02	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54921	522
FHH-Chr 13BN/Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	12			0.01	umol/l	0.0	0.01	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54932	522
SS-Chr 20BN/Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	10			0.04	umol/l	0.01	0.03	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54936	522
SS-Chr 18BN/Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	19			0.02	umol/l	0.01	0.03	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54949	522
SS-Chr 4BN/Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	10			0.06	umol/l	0.03	0.08	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54951	522
SS-Chr 4BN/Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	10			0.04	umol/l	0.02	0.05	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54959	522
SS-Chr XBN/Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	9			0.01	umol/l	0.0	0.01	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54968	522
SS-Chr 2BN/Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	10			0.04	umol/l	0.01	0.03	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54971	522
SS-Chr YBN/Mcwi	concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	20			0.03	10E-7mol/l	0.01	0.03	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56241	522
GH/OmrMcwi	concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	5			0.08	10E-7mol/l	0.01	0.02	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56245	522
SS.BN-(D8Rat163-D8Rat81)/Mcwi	concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	6			0.05	10E-7mol/l	0.01	0.03	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56249	522
SS.BN-(D8Rat163-D8Rat81)/Mcwi	concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	10			0.09	10E-7mol/l	0.02	0.05	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56251	522
SS-Chr 6BN/Mcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	8			36.25	%	5.54	15.66	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56275	522
FHH/EurMcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	9			26.11	%	3.86	11.59	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56283	522
SS-Chr 18BN/Mcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	5			40.0	%	4.73	10.58	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56289	522
BN/NHsdMcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	7			59.0	%	3.48	9.2	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56295	522
SS.BN-(D8Rat163-D8Rat81)/Mcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	7			23.14	%	3.27	8.65	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56294	522
SS-Chr 16BN/Mcwi	sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	9			100.0	%	0.0	0.0	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56309	522
FHH-Ghsrm1Mcwi	serum bicarbonate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bicarbonate amount	male	70 days-84 days	15			16.4	mmol/l	0.48	1.84	standard blood chemistry panel				0					61647	527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi	serum bicarbonate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bicarbonate amount	male	70 days-84 days	3			19.67	mmol/l	0.67	1.15	standard blood chemistry panel				0					61657	527
F344-Nrg1Tn(sb-T2/Bart3)2.183Mcwi	serum bicarbonate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bicarbonate amount	male	70 days-84 days	5			19.6	mmol/l	0.68	1.52	standard blood chemistry panel				0					61667	527
FHH-Lcatm1Mcwi	blood monocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	monocyte quantity	female	70 days-84 days	15			0.19	x 1000 cells/ul	0.04	0.15	automated blood cell counting method				0					61681	527
F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi	blood monocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	monocyte quantity	male	70 days-84 days	3			0.23	x 1000 cells/ul	0.11	0.19	automated blood cell counting method				0					61692	527
FHH-Htr1am1Mcwi	blood monocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	monocyte quantity	female	70 days-84 days	13			0.14	x 1000 cells/ul	0.03	0.13	automated blood cell counting method				0					61694	527
FHH-Procm1Mcwi	blood monocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	monocyte quantity	male	70 days-84 days	9			0.14	x 1000 cells/ul	0.06	0.19	automated blood cell counting method				0					61700	527
F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi	blood monocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	monocyte quantity	female	70 days-84 days	1			0.0	x 1000 cells/ul			automated blood cell counting method				0					61697	527
FHH-Ghsrm1Mcwi	blood monocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	monocyte quantity	female	70 days-84 days	9			0.11	x 1000 cells/ul	0.05	0.15	automated blood cell counting method				0					61711	527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi	blood monocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	monocyte quantity	female	70 days-84 days	2			0.18	x 1000 cells/ul	0.08	0.11	automated blood cell counting method				0					61716	527
FHH-Adipoqm3Mcwi	blood monocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	monocyte quantity	female	70 days-84 days	6			0.18	x 1000 cells/ul	0.06	0.13	automated blood cell counting method				0					61722	527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi	blood monocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	monocyte quantity	female	70 days-84 days	2			0.04	x 1000 cells/ul	0.04	0.06	automated blood cell counting method				0					61733	527
SS-Cpt2m1Mcwi	serum calcium level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood calcium amount	male	70 days-84 days	6			9.32	mg/dl	0.15	0.38	standard blood chemistry panel				0					61742	527
SS-Cpt2m1Mcwi	serum potassium level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	female	70 days-84 days	1			4.1	mmol/l			flame atomic emission spectrometry				0					61757	527
FHH-Tgfbr2m2Mcwi	serum sodium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	male	70 days-84 days	12			140.0	mmol/l	0.44	1.54	flame atomic emission spectrometry				0					61774	527
BN-Tgfbr2m1Mcwi	serum sodium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	male	70 days-84 days	7			139.86	mmol/l	1.03	2.73	flame atomic emission spectrometry				0					61788	527
FHH-F10m2Mcwi	serum sodium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	male	70 days-84 days	16			139.38	mmol/l	0.49	1.96	flame atomic emission spectrometry				0					61798	527
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi	serum sodium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	female	70 days-84 days	4			143.5	mmol/l	1.55	3.11	flame atomic emission spectrometry				0					61812	527
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi	serum sodium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	male	70 days-84 days	1			142.0	mmol/l			flame atomic emission spectrometry				0					61811	527
F344-DccTn(sb-T2/Bart3)2.205Mcwi	serum sodium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	female	70 days-84 days	4			139.75	mmol/l	3.3	6.6	flame atomic emission spectrometry				0					61810	527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi	serum sodium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	female	70 days-84 days	2			140.0	mmol/l	1.0	1.41	flame atomic emission spectrometry				0					61818	527
F344-Plcb3Tn(sb-T2/Bart3)2.69Mcwi	serum sodium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	female	70 days-84 days	3			140.67	mmol/l	1.2	2.08	flame atomic emission spectrometry				0					61820	527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi	serum sodium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	female	70 days-84 days	4			142.25	mmol/l	0.75	1.5	flame atomic emission spectrometry				0					61828	527
FHH-Adra1am1Mcwi	serum sodium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	male	70 days-84 days	8			141.25	mmol/l	0.77	2.19	flame atomic emission spectrometry				0					61827	527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi	serum sodium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	male	70 days-84 days	3			140.0	mmol/l	0.0	0.0	flame atomic emission spectrometry				0					61831	527
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi	serum sodium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	female	70 days-84 days	2			142.5	mmol/l	1.5	2.12	flame atomic emission spectrometry				0					61832	527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi	serum sodium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	female	70 days-84 days	2			138.0	mmol/l	1.0	1.41	flame atomic emission spectrometry				0					61835	527
F344-Nrg1Tn(sb-T2/Bart3)2.183Mcwi	serum sodium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	female	70 days-84 days	5			140.6	mmol/l	1.47	3.29	flame atomic emission spectrometry				0					61838	527
BN/NHsdMcwi	serum sodium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	male	70 days-84 days	44			141.27	mmol/l	0.43	2.86	flame atomic emission spectrometry				0					61839	527
Crl:CD(SD)	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	9			42.78	%	4.97	14.92	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	55001	522
LE/BluGill	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	14			33.71	%	3.38	12.65	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	55002	522
SS.BN-(D12Arb13-D12Rat79)/Mcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	13			40.23	%	4.6	16.59	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	55078	522
SS-Chr 6BN/Mcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	8			28.25	%	5.29	14.95	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	55075	522
FHH-Chr 1BN/Mcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	14			13.07	%	3.87	14.47	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	55097	522
SS/JrHsdMcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	14			84.07	%	4.74	17.72	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	55100	522
LE/BluGill	logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	14			-8.48	null	0.06	0.24	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	55116	522
SS-Chr 10BN/Mcwi	body weight	controlled sodium content diet (4 %) (for 21 days)	PhysGen Vascular data	body mass	male	70 days-84 days	10			324.9	g	6.0	19.0	whole body digital scale				0				Moms and pups used in studies were fed Teklad	55160	522
SS-Chr 10BN/Mcwi	body weight	controlled sodium content diet (4 %) (for 21 days)	PhysGen Vascular data	body mass	female	70 days-84 days	10			203.4	g	6.2	19.8	whole body digital scale				0				Moms and pups used in studies were fed Teklad	55174	522
SS-Chr 7BN/Mcwi	body weight	controlled sodium content diet (4 %) (for 21 days)	PhysGen Vascular data	body mass	female	70 days-84 days	12			187.6	g	2.3	7.8	whole body digital scale				0				Moms and pups used in studies were fed Teklad	55186	522
SHR/NCrl	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	8			45.63	%	1.58	4.47	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	56441	522
GH/OmrMcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	6			47.33	%	5.9	14.45	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	56443	522
SS-Chr 10BN/Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	7			2.89	E-7mole	0.69	1.82	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56495	522
Hsd:SD	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	14			-7.49	null	0.09	0.32	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter	Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	56492	522
SS-Chr 6BN/Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	17			6.71	E-7mole	2.23	9.19	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56509	522
FHH-Chr 17BN/Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	10			1.48	E-7mole	0.19	0.61	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56523	522
FHH-Chr XBN/Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	10			1.02	E-7mole	0.09	0.29	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56526	522
FHH-Chr 10BN/Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	9			1.76	E-7mole	0.28	0.83	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56528	522
SS-Chr 15BN/Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	10			1.23	E-7mole	0.16	0.49	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56539	522
SS-Chr 15BN/Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	8			2.23	E-7mole	0.45	1.27	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56537	522
FHH/EurMcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	10			1.58	E-7mole	0.24	0.77	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56534	522
SS/JrHsdMcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	13			1.46	E-7mole	0.26	0.95	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56566	522
SS-Chr 2BN/Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	14			0.92	E-7mole	0.33	1.25	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56577	522
BN/NHsdMcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	18			3.1	E-7mole	0.51	2.18	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56580	522
FHH-Chr 1BN/Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	17			1.61	E-7mole	0.35	1.44	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56586	522
F344-Elmod3Tn(sb-T2/Bart3)2.42Mcwi	blood lymphocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	lymphocyte quantity	female	70 days-84 days	3			4.29	x 1000 cells/ul	0.87	1.51	automated blood cell counting method				0					62061	527
FHH-Adipoqm2Mcwi	blood lymphocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	lymphocyte quantity	male	70 days-84 days	5			3.68	x 1000 cells/ul	0.45	1.01	automated blood cell counting method				0					62067	527
F344/NHsd	blood lymphocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	lymphocyte quantity	male	70 days-84 days	7			3.77	x 1000 cells/ul	0.62	1.65	automated blood cell counting method				0					62073	527
FHH-Htr1am1Mcwi	blood lymphocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	lymphocyte quantity	female	70 days-84 days	13			4.28	x 1000 cells/ul	0.23	0.81	automated blood cell counting method				0					62072	527
FHH-Nr4a1m1Mcwi	blood lymphocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	lymphocyte quantity	male	70 days-84 days	11			5.65	x 1000 cells/ul	0.63	2.09	automated blood cell counting method				0					62077	527
FHH-Htr1am1Mcwi	blood lymphocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	lymphocyte quantity	male	70 days-84 days	21			4.04	x 1000 cells/ul	0.18	0.83	automated blood cell counting method				0					62080	527
FHH-F10m2Mcwi	blood lymphocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	lymphocyte quantity	female	70 days-84 days	12			3.78	x 1000 cells/ul	0.35	1.2	automated blood cell counting method				0					62083	527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi	blood lymphocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	lymphocyte quantity	female	70 days-84 days	2			3.86	x 1000 cells/ul	0.11	0.16	automated blood cell counting method				0					62094	527
F344-Plcb3Tn(sb-T2/Bart3)2.69Mcwi	blood lymphocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	lymphocyte quantity	female	70 days-84 days	3			3.7	x 1000 cells/ul	0.42	0.72	automated blood cell counting method				0					62096	527
FHH-Ghsrm1Mcwi	blood lymphocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	lymphocyte quantity	male	70 days-84 days	15			4.3	x 1000 cells/ul	0.3	1.16	automated blood cell counting method				0					62097	527
FHH-Adipoqm3Mcwi	blood lymphocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	lymphocyte quantity	female	70 days-84 days	6			3.79	x 1000 cells/ul	0.68	1.66	automated blood cell counting method				0					62100	527
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi	blood lymphocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	lymphocyte quantity	female	70 days-84 days	2			4.09	x 1000 cells/ul	1.13	1.59	automated blood cell counting method				0					62108	527
BN/NHsdMcwi	blood lymphocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	lymphocyte quantity	female	70 days-84 days	27			5.94	x 1000 cells/ul	0.39	2.0	automated blood cell counting method				0					62116	527
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi	blood lymphocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	lymphocyte quantity	male	70 days-84 days	4			4.38	x 1000 cells/ul	0.23	0.45	automated blood cell counting method				0					62118	527
FHH-Nr0b2m1Mcwi	serum total bilirubin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bilirubin amount	female	70 days-84 days	6			0.13	mg/dl	0.02	0.05	standard blood chemistry panel				0					62119	527
F344-Plce1Tn(sb-T2/Bart3)2.146Mcwi	serum total bilirubin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bilirubin amount	male	70 days-84 days	6			0.11	mg/dl	0.02	0.05	standard blood chemistry panel				0					62129	527
FHH-Nr0b2m1Mcwi	serum total bilirubin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bilirubin amount	male	70 days-84 days	10			0.1	mg/dl	0.0	0.0	standard blood chemistry panel				0					62135	527
F344/NHsd	serum total bilirubin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bilirubin amount	male	70 days-84 days	7			0.07	mg/dl	0.01	0.03	standard blood chemistry panel				0					62145	527
FHH-Adra1am1Mcwi	serum total bilirubin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bilirubin amount	male	70 days-84 days	8			0.09	mg/dl	0.01	0.02	standard blood chemistry panel				0					62175	527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi	serum total bilirubin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bilirubin amount	female	70 days-84 days	4			0.13	mg/dl	0.03	0.05	standard blood chemistry panel				0					62176	527
FHH-Egln3m1Mcwi	serum total bilirubin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bilirubin amount	female	70 days-84 days	14			0.19	mg/dl	0.01	0.05	standard blood chemistry panel				0					62184	527
SS-Sod3m1Mcwi	serum alanine aminotransferase activity level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alanine transaminase amount	male	70 days-84 days	10			90.3	U/l	29.22	92.42	standard blood chemistry panel				0					62194	527
SS/JrHsdMcwi	serum alanine aminotransferase activity level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alanine transaminase amount	female	70 days-84 days	17			40.94	U/l	3.17	13.06	standard blood chemistry panel				0					62199	527
FHH-Tgfbr2m2Mcwi	blood eosinophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	eosinophil quantity	male	70 days-84 days	13			0.06	x 1000 cells/ul	0.02	0.05	automated blood cell counting method				0					62204	527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi	blood eosinophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	eosinophil quantity	male	70 days-84 days	1			0.0	x 1000 cells/ul			automated blood cell counting method				0					62205	527
FHH-Adipoqm2Mcwi	blood eosinophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	eosinophil quantity	female	70 days-84 days	12			0.05	x 1000 cells/ul	0.01	0.04	automated blood cell counting method				0					62203	527
F344-Elmod3Tn(sb-T2/Bart3)2.42Mcwi	blood eosinophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	eosinophil quantity	male	70 days-84 days	5			0.07	x 1000 cells/ul	0.03	0.06	automated blood cell counting method				0					62208	527
FHH-Tgfbr2m2Mcwi	blood eosinophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	eosinophil quantity	female	70 days-84 days	14			0.05	x 1000 cells/ul	0.02	0.06	automated blood cell counting method				0					62210	527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi	blood eosinophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	eosinophil quantity	female	70 days-84 days	2			0.0	x 1000 cells/ul	0.0	0.0	automated blood cell counting method				0					62212	527
FHH-Slc8a2m1Mcwi	blood eosinophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	eosinophil quantity	female	70 days-84 days	11			0.04	x 1000 cells/ul	0.01	0.05	automated blood cell counting method				0					62214	527
F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi	blood eosinophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	eosinophil quantity	female	70 days-84 days	1			0.0	x 1000 cells/ul			automated blood cell counting method				0					62229	527
FHH-F10m2Mcwi	blood eosinophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	eosinophil quantity	male	70 days-84 days	16			0.07	x 1000 cells/ul	0.02	0.06	automated blood cell counting method				0					62228	527
FHH-Nr4a1m1Mcwi	blood eosinophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	eosinophil quantity	male	70 days-84 days	11			0.07	x 1000 cells/ul	0.03	0.08	automated blood cell counting method				0					62231	527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi	blood eosinophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	eosinophil quantity	female	70 days-84 days	4			0.0	x 1000 cells/ul	0.0	0.0	automated blood cell counting method				0					62258	527
SS-Kcnq1em14Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	7			340.57	beats/min	13.34	35.3	radiotelemetry	carotid artery			0				-	43706	441
SS-Cyp1a1em2Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			341.0	beats/min	18.0	25.46	radiotelemetry	carotid artery			0				-	43724	441
SS-Plcd3em4Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	9			322.67	beats/min	10.58	31.74	radiotelemetry	carotid artery			0				-	43727	441
SS-Plekha7em4Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	12			372.0	beats/min	6.02	20.86	radiotelemetry	carotid artery			0				-	43728	441
SS-Cyp1a1em5Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			364.0	beats/min	3.0	4.24	radiotelemetry	carotid artery			0				-	43735	441
SS-Ulk3em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	3			366.67	beats/min	7.31	12.66	radiotelemetry	carotid artery			0				-	43738	441
SS-Aldh2em2Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	6			364.17	beats/min	7.78	19.06	radiotelemetry	carotid artery			0				-	43736	441
SS-Cyp1a1em1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	7			356.14	beats/min	7.11	18.81	radiotelemetry	carotid artery			0				-	43744	441
SS-Agtr1aem1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	10			339.7	beats/min	11.64	36.82	radiotelemetry	carotid artery			0				-	43754	441
SS-Plcd3em4Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			338.0	beats/min	15.0	21.21	radiotelemetry	carotid artery			0				-	43762	441
SS-Nppbem4Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	8	1/3 systolic pressure + 2/3 diastolic pressure		132.38	mmHg	4.44	12.56	radiotelemetry	carotid artery			0				-	43773	441
SS-Cdh13em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	1/3 systolic pressure + 2/3 diastolic pressure		130.0	mmHg	4.38	8.76	radiotelemetry	carotid artery			0				-	43775	441
SS-Slc30a8em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	1/3 systolic pressure + 2/3 diastolic pressure		137.0	mmHg	2.04	4.08	radiotelemetry	carotid artery			0				-	43776	441
SS-Plod1em1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	8	1/3 systolic pressure + 2/3 diastolic pressure		132.85	mmHg	6.05	17.1	radiotelemetry	carotid artery			0				-	43791	441
SS-Plekha7em4Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		151.5	mmHg	9.5	13.44	radiotelemetry	carotid artery			0				-	43788	441
SS-Plcd3em4Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	9	1/3 systolic pressure + 2/3 diastolic pressure		135.33	mmHg	5.61	16.82	radiotelemetry	carotid artery			0				-	43789	441
SS-Mstnem3Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	7	1/3 systolic pressure + 2/3 diastolic pressure		125.29	mmHg	4.64	12.28	radiotelemetry	carotid artery			0				-	43799	441
SS-Msraem3Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	1	1/3 systolic pressure + 2/3 diastolic pressure		147.0	mmHg			radiotelemetry	carotid artery			0				-	43804	441
SS/JrHsdMcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	6	1/3 systolic pressure + 2/3 diastolic pressure		131.0	mmHg	6.09	14.93	radiotelemetry	carotid artery			0				-	43807	441
SS-Mstnem1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	3	1/3 systolic pressure + 2/3 diastolic pressure		124.67	mmHg	6.06	10.5	radiotelemetry	carotid artery			0				-	43818	441
SS-Slc30a8em2Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	11	1/3 systolic pressure + 2/3 diastolic pressure		142.73	mmHg	4.81	15.97	radiotelemetry	carotid artery			0				-	43820	441
SS-Plcd3em4Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		143.5	mmHg	17.5	24.75	radiotelemetry	carotid artery			0				-	43824	441
SS-Stk39em2Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	3	1/3 systolic pressure + 2/3 diastolic pressure		140.33	mmHg	16.13	27.93	radiotelemetry	carotid artery			0				-	43828	441
SS-Msraem4Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	1/3 systolic pressure + 2/3 diastolic pressure		138.5	mmHg	10.46	20.92	radiotelemetry	carotid artery			0				-	43834	441
SS-Cdh13em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	1/3 systolic pressure + 2/3 diastolic pressure		137.0	mmHg	2.94	5.89	radiotelemetry	carotid artery			0				-	43837	441
SS-Mstnem3Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		144.0	mmHg	6.0	8.49	radiotelemetry	carotid artery			0				-	43844	441
SS-Ulk3em1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	11	1/3 systolic pressure + 2/3 diastolic pressure		140.45	mmHg	4.9	16.25	radiotelemetry	carotid artery			0				-	43846	441
SS-Mstnem3Mcwi-/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	1	1/3 systolic pressure + 2/3 diastolic pressure		124.0	mmHg			radiotelemetry	carotid artery			0				-	43849	441
SS-Aldh2em2Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	6	1/3 systolic pressure + 2/3 diastolic pressure		151.67	mmHg	10.92	26.76	radiotelemetry	carotid artery			0				-	43864	441
SS-Ulk3em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	3	1/3 systolic pressure + 2/3 diastolic pressure		136.33	mmHg	5.55	9.61	radiotelemetry	carotid artery			0				-	43862	441
SS-Plod1em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	1/3 systolic pressure + 2/3 diastolic pressure		142.25	mmHg	2.78	5.56	radiotelemetry	carotid artery			0				-	43870	441
SS-Agtr1aem1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	9	1/3 systolic pressure + 2/3 diastolic pressure		142.67	mmHg	4.37	13.11	radiotelemetry	carotid artery			0				-	43878	441
SS-Stk39em2Mcwi+/+	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	6			324.5	g	7.3	17.9	whole body digital scale				0				-	43891	441
SS-Kcnq1em14Mcwi-/-	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	7			251.0	g	3.7	9.7	whole body digital scale				0				-	43893	441
SS-Agtrapem8Mcwi-/-	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	10			327.4	g	3.9	12.3	whole body digital scale				0				-	43899	441
SS-Cyp1a1em1Mcwi+/+	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	3			307.3	g	16.5	28.6	whole body digital scale				0				-	43910	441
WKY/NCrl	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	10			71.9	%	3.29	10.42	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56710	522
SS-Chr 16BN/Mcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	3			58.67	%	8.35	14.47	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	56716	522
SS/JrHsdMcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	12			1.38	g/mg	0.11	0.39	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	56757	522
SS/JrHsdMcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	10			1.84	g/mg	0.09	0.28	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	56759	522
LEW/Crl	concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	23			0.01	10E-7mol/l	0.0	0.01	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56763	522
F344/DuCrl	concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	14			0.05	10E-7mol/l	0.01	0.04	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56765	522
WKY/NCrl	concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	9			0.05	10E-7mol/l	0.01	0.02	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56769	522
Hsd:SD	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	15			65.48	%	5.85	22.64	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	56782	522
WKY/NCrl	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	13			29.0	%	2.97	10.69	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56825	522
F344/DuCrl	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	18			32.94	%	5.29	22.42	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56833	522
FHH-Tgfbr2m2Mcwi	serum urea nitrogen level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood urea nitrogen amount	male	70 days-84 days	12			19.58	mg/dl	0.47	1.62	standard blood chemistry panel				0					60144	527
FHH-Lcatm1Mcwi	serum urea nitrogen level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood urea nitrogen amount	male	70 days-84 days	13			20.08	mg/dl	1.13	4.07	standard blood chemistry panel				0					60146	527
F344-Elmod3Tn(sb-T2/Bart3)2.42Mcwi	serum urea nitrogen level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood urea nitrogen amount	female	70 days-84 days	3			24.33	mg/dl	1.45	2.52	standard blood chemistry panel				0					60155	527
FHH-Nr0b2m1Mcwi	serum urea nitrogen level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood urea nitrogen amount	male	70 days-84 days	10			18.8	mg/dl	0.49	1.55	standard blood chemistry panel				0					60157	527
FHH-Ccr2m1Mcwi	serum urea nitrogen level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood urea nitrogen amount	female	70 days-84 days	5			17.8	mg/dl	0.86	1.92	standard blood chemistry panel				0					60162	527
FHH-Agtr1bm1Mcwi	serum alanine aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alanine transaminase amount	male	70 days-84 days	15			53.67	U/l	3.54	13.72	standard blood chemistry panel				0					61441	527
F344-Plcb3Tn(sb-T2/Bart3)2.69Mcwi	serum urea nitrogen level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood urea nitrogen amount	male	70 days-84 days	1			22.0	mg/dl			standard blood chemistry panel				0					60187	527
FHH-Slc8a2m1Mcwi	serum alanine aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alanine transaminase amount	female	70 days-84 days	12			44.0	U/l	4.04	14.0	standard blood chemistry panel				0					61446	527
FHH-F10m1Mcwi	serum alanine aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alanine transaminase amount	female	70 days-84 days	11			44.0	U/l	4.36	14.46	standard blood chemistry panel				0					61455	527
FHH-F10m2Mcwi	serum alanine aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alanine transaminase amount	male	70 days-84 days	16			51.5	U/l	3.92	15.69	standard blood chemistry panel				0					61460	527
F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi	serum alanine aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alanine transaminase amount	female	70 days-84 days	1			36.0	U/l			standard blood chemistry panel				0					61461	527
F344-DccTn(sb-T2/Bart3)2.205Mcwi	serum alanine aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alanine transaminase amount	male	70 days-84 days	6			58.67	U/l	11.18	27.38	standard blood chemistry panel				0					61485	527
FHH-Adra1am1Mcwi	serum alanine aminotransferase activity level	controlled sodium content diet (4 %) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alanine transaminase amount	female	70 days-84 days	9			46.11	U/l	4.92	14.76	standard blood chemistry panel				0					61491	527
F344-Inpp4bTn(sb-T2/Bart3)2.143Mcwi	serum alanine aminotransferase activity level	controlled sodium content diet (4 %) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alanine transaminase amount	male	70 days-84 days	7			63.0	U/l	7.12	18.83	standard blood chemistry panel				0					61499	527
SS/JrHsdMcwi	red blood cell count	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	male	70 days-84 days	41			8.42	x 10E6 cells/ul	0.09	0.6	automated blood cell counting method				0					61507	527
SS-Klf4m3Mcwi	red blood cell count	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	male	70 days-84 days	8			8.06	x 10E6 cells/ul	0.14	0.39	automated blood cell counting method				0					61510	527
SS-Ghsrm3Mcwi	red blood cell count	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	female	70 days-84 days	1			8.08	x 10E6 cells/ul			automated blood cell counting method				0					61512	527
SS-Sod3m1Mcwi	red blood cell count	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	female	70 days-84 days	10			8.02	x 10E6 cells/ul	0.11	0.36	automated blood cell counting method				0					61514	527
SS-Cpt2m1Mcwi	plasma creatinine level	controlled sodium content diet (1 %) (for 14 days) then fasting (between 16 and 1 hours)	PhysGen Biochemistry data	blood creatinine amount	male	70 days-84 days	6			0.62	mg/dl	0.11	0.26	automated plasma creatinine analysis				0					61516	527
SS-Cpt2m1Mcwi	plasma creatinine level	controlled sodium content diet (1 %) (for 14 days) then fasting (between 16 and 1 hours)	PhysGen Biochemistry data	blood creatinine amount	female	70 days-84 days	1			0.8	mg/dl			automated plasma creatinine analysis				0					61521	527
SS/JrHsdMcwi	plasma creatinine level	controlled sodium content diet (1 %) (for 14 days) then fasting (between 16 and 1 hours)	PhysGen Biochemistry data	blood creatinine amount	female	70 days-84 days	17			0.33	mg/dl	0.02	0.08	automated plasma creatinine analysis				0					61523	527
FHH-Adipoqm1Mcwi	serum phosphate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood phosphate amount	female	70 days-84 days	9			6.43	mg/dl	0.61	1.82	standard blood chemistry panel				0					61526	527
FHH-Lcatm1Mcwi	serum phosphate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood phosphate amount	male	70 days-84 days	13			9.55	mg/dl	0.83	3.0	standard blood chemistry panel				0					61530	527
FHH-Agtr1bm1Mcwi	serum phosphate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood phosphate amount	male	70 days-84 days	15			7.99	mg/dl	0.12	0.46	standard blood chemistry panel				0					61533	527
FHH-Tgfbr2m2Mcwi	serum phosphate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood phosphate amount	female	70 days-84 days	11			7.92	mg/dl	0.64	2.11	standard blood chemistry panel				0					61534	527
FHH-Agtr1bm1Mcwi	serum phosphate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood phosphate amount	female	70 days-84 days	14			7.24	mg/dl	0.15	0.56	standard blood chemistry panel				0					61540	527
F344/NHsd	serum phosphate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood phosphate amount	male	70 days-84 days	7			8.44	mg/dl	0.32	0.84	standard blood chemistry panel				0					61551	527
FHH-Nr4a1m1Mcwi	serum phosphate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood phosphate amount	female	70 days-84 days	11			8.12	mg/dl	0.69	2.29	standard blood chemistry panel				0					61563	527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi	serum phosphate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood phosphate amount	female	70 days-84 days	2			4.2	mg/dl	3.9	5.52	standard blood chemistry panel				0					61572	527
F344-Plcb3Tn(sb-T2/Bart3)2.69Mcwi	serum phosphate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood phosphate amount	female	70 days-84 days	3			6.87	mg/dl	0.78	1.34	standard blood chemistry panel				0					61574	527
FHH-Adipoqm3Mcwi	serum phosphate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood phosphate amount	male	70 days-84 days	5			8.46	mg/dl	1.21	2.7	standard blood chemistry panel				0					61579	527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi	serum phosphate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood phosphate amount	male	70 days-84 days	3			8.33	mg/dl	0.55	0.95	standard blood chemistry panel				0					61585	527
FHH-Agtr1bm1Mcwi	serum bicarbonate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bicarbonate amount	female	70 days-84 days	14			17.79	mmol/l	0.67	2.52	standard blood chemistry panel				0					61612	527
FHH-Slc8a2m1Mcwi	serum bicarbonate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bicarbonate amount	female	70 days-84 days	12			13.92	mmol/l	1.16	4.03	standard blood chemistry panel				0					61610	527
FHH-F10m2Mcwi	serum bicarbonate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bicarbonate amount	male	70 days-84 days	16			16.44	mmol/l	1.26	5.06	standard blood chemistry panel				0					61624	527
SS-Plcd3em4Mcwi-/-	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	13			310.8	g	5.1	18.4	whole body digital scale				0				-	43914	441
SS-Plod1em1Mcwi+/+	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	5			307.2	g	14.7	32.9	whole body digital scale				0				-	43933	441
SS-Nppaem4Mcwi-/-	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	13			72.53	mg/d	8.27	29.81	automated urine analysis				0				-	43950	441
SS-Prokr1em2Mcwi+/+	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	6			70.44	mg/d	12.79	31.32	automated urine analysis				0				-	43952	441
SS-Slc30a8em1Mcwi+/+	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	4			127.37	mg/d	5.84	11.69	automated urine analysis				0				-	43963	441
SS-Mstnem1Mcwi-/-	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	13			79.34	mg/d	9.3	33.54	automated urine analysis				0				-	43966	441
SS-Mstnem3Mcwi-/-	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	3			56.3	mg/d	2.31	4.0	automated urine analysis				0				-	43968	441
SS-Plekha7em1Mcwi-/-	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	9			79.69	mg/d	6.5	19.5	automated urine analysis				0				-	43979	441
SS-Cyp1a1em5Mcwi-/-	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	2			77.71	mg/d	6.98	9.88	automated urine analysis				0				-	43983	441
SS-Plcd3em7Mcwi-/-	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	9			108.74	mg/d	9.87	29.6	automated urine analysis				0				-	43987	441
SS-Cyp1a1em1Mcwi-/-	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	7			72.43	mg/d	9.46	25.04	automated urine analysis				0				-	43992	441
SS-Wdr72em1Mcwi+/+	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	2			77.22	mg/d	11.0	15.56	automated urine analysis				0				-	43995	441
SS-Slc30a8em2Mcwi+/+	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	1			46.59	mg/d			automated urine analysis				0				-	43997	441
SS-Stk39em2Mcwi-/-	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	10			50.85	mg/d	6.03	19.06	automated urine analysis				0				-	43999	441
SS-Slc30a8em2Mcwi-/-	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	10			105.78	mg/d	9.72	30.74	automated urine analysis				0				-	44006	441
SS-Msraem4Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	4			353.5	beats/min	8.22	16.44	radiotelemetry	carotid artery			0				-	44020	441
SS-Tcf7l2em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	4			342.0	beats/min	13.82	27.64	radiotelemetry	carotid artery			0				-	44028	441
SS-Plekha7em1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	8			352.13	beats/min	6.55	18.51	radiotelemetry	carotid artery			0				-	44041	441
SS-Aldh2em2Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	6			365.33	beats/min	8.22	20.14	radiotelemetry	carotid artery			0				-	44050	441
SS-Wdr72em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			350.0	beats/min	9.0	12.73	radiotelemetry	carotid artery			0				-	44057	441
SS-Agtrapem8Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			345.5	beats/min	7.5	10.61	radiotelemetry	carotid artery			0				-	44058	441
SS-Plekha7em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	6	1/3 systolic pressure + 2/3 diastolic pressure		137.17	mmHg	4.8	11.75	radiotelemetry	carotid artery			0				-	44079	441
SS-Tcf7l2em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	5	1/3 systolic pressure + 2/3 diastolic pressure		144.6	mmHg	4.3	9.61	radiotelemetry	carotid artery			0				-	44090	441
SS-Wdr72em1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	1	1/3 systolic pressure + 2/3 diastolic pressure		108.0	mmHg			radiotelemetry	carotid artery			0				-	44093	441
SS-Mstnem3Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		116.0	mmHg	9.0	12.73	radiotelemetry	carotid artery			0				-	44092	441
SS-Plcd3em7Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	1	1/3 systolic pressure + 2/3 diastolic pressure		120.0	mmHg			radiotelemetry	carotid artery			0				-	44113	441
SS/JrHsdMcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	7	1/3 systolic pressure + 2/3 diastolic pressure		130.57	mmHg	4.7	12.45	radiotelemetry	carotid artery			0				-	44116	441
SS-Plod1em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	1/3 systolic pressure + 2/3 diastolic pressure		145.75	mmHg	6.05	12.09	radiotelemetry	carotid artery			0				-	44117	441
SS-Agtr1aem1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	9	1/3 systolic pressure + 2/3 diastolic pressure		134.67	mmHg	4.68	14.03	radiotelemetry	carotid artery			0				-	44125	441
Crl:CD(SD)	sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	10			71.9	%	8.91	28.16	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56853	522
F344/DuCrl	sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	14			99.71	%	0.29	1.07	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56854	522
WKY/NCrl	sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	14			99.29	%	0.27	0.99	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56851	522
F344/DuCrl	sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	11			99.91	%	0.09	0.3	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56859	522
LEW/Crl	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	24			1.3	g/mg	0.06	0.3	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56867	522
SS-Chr 18BN/Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	10			0.11	umol/l	0.02	0.07	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	56879	522
SS/JrHsdMcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	15			0.19	umol/l	0.07	0.28	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	56883	522
GH/OmrMcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	10			0.11	umol/l	0.03	0.09	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	56885	522
FHH-Chr 15BN/Mcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	7			-6.99	null	0.09	0.23	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56888	522
SS.BN-(D12Arb13-D12Rat79)/Mcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	11			-7.15	null	0.1	0.34	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56899	522
SS-Chr 6BN/Mcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	17			-6.61	null	0.13	0.54	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56904	522
GH/OmrMcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	3			-6.66	null	0.11	0.18	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56919	522
FHH-Chr 8BN/Mcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	10			-6.81	null	0.12	0.38	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56926	522
FHH-Chr 19BN/Mcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	7			-6.85	null	0.03	0.07	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56935	522
FHH-Chr 11BN/Mcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	9			-6.84	null	0.11	0.33	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56967	522
FHH-Chr 7BN/Mcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	10			-6.96	null	0.07	0.22	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56970	522
FHH/EurMcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	10			1.23	g/mg	0.11	0.35	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	56984	522
FHH/EurMcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	10			1.36	g/mg	0.14	0.43	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	56990	522
GH/OmrMcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	10			1.0	g/mg	0.08	0.26	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	56993	522
FHH-Adipoqm1Mcwi	serum calcium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood calcium amount	female	70 days-84 days	9			9.96	mg/dl	0.13	0.39	standard blood chemistry panel				0					60214	527
FHH-Agtr1bm1Mcwi	serum calcium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood calcium amount	female	70 days-84 days	14			9.94	mg/dl	0.11	0.41	standard blood chemistry panel				0					60228	527
BN-Tgfbr2m1Mcwi	serum calcium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood calcium amount	male	70 days-84 days	7			10.03	mg/dl	0.18	0.47	standard blood chemistry panel				0					60230	527
FHH-Ccr2m1Mcwi	serum calcium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood calcium amount	female	70 days-84 days	5			9.32	mg/dl	0.25	0.57	standard blood chemistry panel				0					60234	527
FHH-F10m2Mcwi	serum calcium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood calcium amount	male	70 days-84 days	16			10.06	mg/dl	0.09	0.36	standard blood chemistry panel				0					60240	527
FHH-Htr1am1Mcwi	serum calcium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood calcium amount	male	70 days-84 days	21			9.74	mg/dl	0.08	0.35	standard blood chemistry panel				0					60246	527
F344/NHsd	serum calcium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood calcium amount	female	70 days-84 days	4			8.55	mg/dl	0.1	0.21	standard blood chemistry panel				0					60248	527
FHH-Ghsrm1Mcwi	serum calcium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood calcium amount	female	70 days-84 days	9			9.93	mg/dl	0.15	0.45	standard blood chemistry panel				0					60255	527
BN-Lcatm3Mcwi	serum calcium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood calcium amount	female	70 days-84 days	2			9.1	mg/dl	0.2	0.28	standard blood chemistry panel				0					60258	527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi	serum calcium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood calcium amount	female	70 days-84 days	4			9.82	mg/dl	0.64	1.29	standard blood chemistry panel				0					60270	527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi	serum calcium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood calcium amount	female	70 days-84 days	2			9.0	mg/dl	0.0	0.0	standard blood chemistry panel				0					60277	527
BN/NHsdMcwi	serum calcium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood calcium amount	female	70 days-84 days	27			9.97	mg/dl	0.09	0.47	standard blood chemistry panel				0					60282	527
SS-Klf4m3Mcwi	total white blood cell count	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	leukocyte quantity	male	70 days-84 days	8			8.49	x 1000 cells/ul	1.04	2.94	automated blood cell counting method				0					60290	527
BN-Tgfbr2m1Mcwi	blood hemoglobin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	3			14.67	g/dl	0.19	0.32	automated blood cell counting method				0					60301	527
FHH-Adipoqm2Mcwi	blood hemoglobin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	12			13.82	g/dl	0.69	2.38	automated blood cell counting method				0					60297	527
BN-Tgfbr2m1Mcwi	blood hemoglobin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	7			14.91	g/dl	0.11	0.3	automated blood cell counting method				0					60312	527
FHH-Adipoqm1Mcwi	blood hemoglobin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	8			15.06	g/dl	0.38	1.07	automated blood cell counting method				0					60313	527
FHH-Htr1am1Mcwi	blood hemoglobin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	13			13.52	g/dl	0.18	0.64	automated blood cell counting method				0					60320	527
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi	blood hemoglobin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	2			15.6	g/dl	0.1	0.14	automated blood cell counting method				0					60329	527
F344-DccTn(sb-T2/Bart3)2.205Mcwi	blood hemoglobin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	4			14.78	g/dl	0.24	0.48	automated blood cell counting method				0					60334	527
FHH-F10m1Mcwi	blood hemoglobin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	10			14.94	g/dl	0.27	0.84	automated blood cell counting method				0					60332	527
FHH-Slc8a2m1Mcwi	blood hemoglobin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	8			16.48	g/dl	0.76	2.16	automated blood cell counting method				0					60357	527
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi	blood hemoglobin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	2			14.85	g/dl	0.95	1.34	automated blood cell counting method				0					60356	527
BN/NHsdMcwi	blood hemoglobin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	27			14.4	g/dl	0.09	0.45	automated blood cell counting method				0					60364	527
SS-Cpt2m1Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	6			18.7	pg	0.14	0.33	automated blood cell counting method				0					60368	527
SS-Sod3m1Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	10			19.0	pg	0.08	0.27	automated blood cell counting method				0					60376	527
F344-Elmod3Tn(sb-T2/Bart3)2.42Mcwi	serum alkaline phosphatase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	female	70 days-84 days	3			110.67	U/l	11.29	19.55	standard blood chemistry panel				0					60401	527
SS-Sod3m1Mcwi	serum globulin level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood globulin amount	female	70 days-84 days	11			1.91	g/dl	0.06	0.2	standard blood chemistry panel				0			replaced obsolete serum globulin level term, 1/19/2016		61872	527
SS-Klf4m3Mcwi	serum globulin level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood globulin amount	male	70 days-84 days	8			2.26	g/dl	0.07	0.18	standard blood chemistry panel				0			replaced obsolete serum globulin level term, 1/19/2016		61868	527
SS-Cpt2m1Mcwi	blood hemoglobin level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	1			12.9	g/dl			automated blood cell counting method				0					61879	527
FHH-Nr0b2m1Mcwi	serum albumin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood albumin amount	female	70 days-84 days	6			3.78	g/dl	0.11	0.27	standard blood chemistry panel				0					61893	527
BN-Tgfbr2m1Mcwi	serum albumin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood albumin amount	female	70 days-84 days	3			3.57	g/dl	0.2	0.35	standard blood chemistry panel				0					61899	527
FHH-Ghsrm1Mcwi	serum albumin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood albumin amount	female	70 days-84 days	7			3.79	g/dl	0.06	0.17	standard blood chemistry panel				0					61935	527
F344-DccTn(sb-T2/Bart3)2.205Mcwi	serum albumin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood albumin amount	female	70 days-84 days	4			3.83	g/dl	0.21	0.41	standard blood chemistry panel				0					61932	527
FHH-Adipoqm3Mcwi	serum albumin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood albumin amount	female	70 days-84 days	6			3.9	g/dl	0.07	0.18	standard blood chemistry panel				0					61946	527
BN/NHsdMcwi	serum albumin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood albumin amount	female	70 days-84 days	27			3.6	g/dl	0.03	0.18	standard blood chemistry panel				0					61962	527
FHH-Adipoqm1Mcwi	serum aspartate aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood aspartate transaminase amount	female	70 days-84 days	9			224.44	U/l	23.7	71.09	standard blood chemistry panel				0					61966	527
FHH-Htr1am1Mcwi	serum aspartate aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood aspartate transaminase amount	female	70 days-84 days	13			184.54	U/l	17.67	63.71	standard blood chemistry panel				0					61990	527
F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi	serum aspartate aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood aspartate transaminase amount	female	70 days-84 days	1			129.0	U/l			standard blood chemistry panel				0					61993	527
FHH-F10m2Mcwi	serum aspartate aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood aspartate transaminase amount	female	70 days-84 days	12			211.83	U/l	23.14	80.17	standard blood chemistry panel				0					62001	527
F344-DccTn(sb-T2/Bart3)2.205Mcwi	serum aspartate aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood aspartate transaminase amount	male	70 days-84 days	6			239.33	U/l	41.61	101.92	standard blood chemistry panel				0					62017	527
FHH/EurMcwi	serum aspartate aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood aspartate transaminase amount	male	70 days-84 days	158			230.06	U/l	18.8	236.33	standard blood chemistry panel				0					62020	527
F344-Inpp4bTn(sb-T2/Bart3)2.143Mcwi	serum aspartate aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood aspartate transaminase amount	male	70 days-84 days	7			216.29	U/l	44.54	117.85	standard blood chemistry panel				0					62031	527
SS-Cyp1a1em2Mcwi-/-	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	10			10.17	mg/d	0.45	1.41	automated urine analysis				0				-	44138	441
SS-Plekha7em1Mcwi+/+	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	6			10.61	mg/d	0.71	1.74	automated urine analysis				0				-	44140	441
SS-Cdh13em1Mcwi+/+	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	4			9.69	mg/d	1.0	2.0	automated urine analysis				0				-	44146	441
SS-Ulk3em1Mcwi-/+	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	3			10.63	mg/d	1.01	1.75	automated urine analysis				0				-	44149	441
SS-Mstnem3Mcwi-/-	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	3			16.43	mg/d	0.6	1.03	automated urine analysis				0				-	44153	441
SS-Agtr1aem5Mcwi-/-	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	2			8.33	mg/d	0.3	0.42	automated urine analysis				0				-	44165	441
SS-Plcd3em4Mcwi-/-	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	13			10.39	mg/d	0.35	1.25	automated urine analysis				0				-	44160	441
SS-Cyp1a1em5Mcwi-/-	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	2			9.62	mg/d	0.34	0.47	automated urine analysis				0				-	44168	441
SS/JrHsdMcwi	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	7			9.31	mg/d	0.42	1.11	automated urine analysis				0				-	44178	441
SS-Wdr72em1Mcwi+/+	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	2			10.26	mg/d	0.06	0.08	automated urine analysis				0				-	44180	441
SS-Mstnem1Mcwi+/+	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	3			10.53	mg/d	0.73	1.26	automated urine analysis				0				-	44189	441
SS-Plcd3em4Mcwi+/+	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	3			11.62	mg/d	0.32	0.55	automated urine analysis				0				-	44195	441
SS-Cyp1a1em5Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	2			10.88	mEq/d	0.47	0.66	automated urine analysis				0				-	44203	441
SS-Msraem4Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	5			8.58	mEq/d	0.79	1.76	automated urine analysis				0				-	44205	441
SS-Ulk3em1Mcwi-/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	3			6.61	mEq/d	3.13	5.43	automated urine analysis				0				-	44211	441
SS-Cyp1a1em1Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	3			9.2	mEq/d	0.51	0.88	automated urine analysis				0				-	44218	441
SS-Tcf7l2em1Mcwi-/-	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	10			9.71	mEq/d	0.94	2.98	automated urine analysis				0				-	44250	441
SS-Nppaem4Mcwi-/-	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	12			25.37	mg/d	2.78	9.62	automated urine analysis				0				-	44258	441
SS-Agtr1aem1Mcwi+/+	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	6			50.27	mg/d	20.21	49.51	automated urine analysis				0				-	44259	441
SS-Msraem3Mcwi-/-	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	3			11.49	mEq/d	0.18	0.32	automated urine analysis				0				-	44254	441
SS-Plekha7em4Mcwi-/-	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	12			32.25	mg/d	5.86	20.29	automated urine analysis				0				-	44285	441
SS-Plekha7em1Mcwi-/-	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	9			31.02	mg/d	3.97	11.9	automated urine analysis				0				-	44288	441
SS-Slc30a8em2Mcwi+/+	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	1			11.57	mg/d			automated urine analysis				0				-	44306	441
SS-Slc30a8em2Mcwi-/-	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	10			54.88	mg/d	6.22	19.68	automated urine analysis				0				-	44315	441
SS-Kcnq1em14Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	7			1.19	g	0.04	0.11	digital scale post excision weight measurement				0				-	44325	441
SS-Nppaem4Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	13			1.36	g	0.02	0.09	digital scale post excision weight measurement				0				-	44320	441
SS/JrHsdMcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	40			54.13	%	2.52	15.94	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	57149	522
SS.BN-(D8Rat163-D8Rat81)/Mcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	7			42.71	%	6.79	17.96	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	57157	522
FHH-Chr 1BN/Mcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	14			44.14	%	5.69	21.28	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	57160	522
FHH-Agtr1bm1Mcwi	serum alkaline phosphatase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	female	70 days-84 days	14			148.86	U/l	10.38	38.84	standard blood chemistry panel				0					60402	527
FHH-Ccr2m1Mcwi	serum alkaline phosphatase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	female	70 days-84 days	5			169.2	U/l	16.47	36.83	standard blood chemistry panel				0					60408	527
FHH-F10m1Mcwi	serum alkaline phosphatase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	female	70 days-84 days	11			193.27	U/l	14.4	47.77	standard blood chemistry panel				0					60409	527
F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi	serum alkaline phosphatase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	male	70 days-84 days	3			169.67	U/l	19.1	33.08	standard blood chemistry panel				0					60410	527
F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi	serum alkaline phosphatase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	female	70 days-84 days	1			110.0	U/l			standard blood chemistry panel				0					60415	527
FHH-Htr1am1Mcwi	serum alkaline phosphatase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	male	70 days-84 days	21			205.86	U/l	5.28	24.19	standard blood chemistry panel				0					60420	527
FHH/EurMcwi	serum alkaline phosphatase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	female	70 days-84 days	25			143.96	U/l	8.55	42.73	standard blood chemistry panel				0					60431	527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi	serum alkaline phosphatase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	female	70 days-84 days	2			110.5	U/l	2.5	3.54	standard blood chemistry panel				0					60434	527
FHH-Adipoqm3Mcwi	serum alkaline phosphatase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	male	70 days-84 days	5			182.4	U/l	38.74	86.62	standard blood chemistry panel				0					60441	527
FHH-Egln3m1Mcwi	serum alkaline phosphatase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	male	70 days-84 days	6			217.67	U/l	11.74	28.74	standard blood chemistry panel				0					60438	527
FHH-Adra1am1Mcwi	serum alkaline phosphatase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	male	70 days-84 days	8			194.0	U/l	4.75	13.44	standard blood chemistry panel				0					60443	527
FHH-Adipoqm3Mcwi	serum alkaline phosphatase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	female	70 days-84 days	6			163.67	U/l	18.96	46.45	standard blood chemistry panel				0					60440	527
FHH-Adra1am1Mcwi	serum alkaline phosphatase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	female	70 days-84 days	9			145.89	U/l	11.53	34.58	standard blood chemistry panel				0					60445	527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi	serum alkaline phosphatase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	female	70 days-84 days	2			103.0	U/l	4.0	5.66	standard blood chemistry panel				0					60451	527
F344-Nrg1Tn(sb-T2/Bart3)2.183Mcwi	serum alkaline phosphatase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	male	70 days-84 days	5			167.2	U/l	3.67	8.2	standard blood chemistry panel				0					60457	527
FHH-Nr0b2m1Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	6			18.08	pg	0.1	0.24	automated blood cell counting method				0					60459	527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	2			18.0	pg	0.0	0.0	automated blood cell counting method				0					60470	527
FHH-Nr0b2m1Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	10			17.51	pg	0.14	0.44	automated blood cell counting method				0					60475	527
FHH-Adipoqm2Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	7			17.17	pg	0.17	0.44	automated blood cell counting method				0					60479	527
FHH-Htr1am1Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	13			18.19	pg	0.15	0.55	automated blood cell counting method				0					60484	527
F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	1			17.8	pg			automated blood cell counting method				0					60487	527
FHH-Nr4a1m1Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	11			17.76	pg	0.12	0.41	automated blood cell counting method				0					60497	527
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	1			17.6	pg			automated blood cell counting method				0					60499	527
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	4			18.05	pg	0.1	0.19	automated blood cell counting method				0					60500	527
FHH-Adipoqm3Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	5			17.32	pg	0.17	0.38	automated blood cell counting method				0					60513	527
F344-DccTn(sb-T2/Bart3)2.205Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	6			17.47	pg	0.15	0.36	automated blood cell counting method				0					60511	527
FHH-Adra1am1Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	9			17.63	pg	0.04	0.11	automated blood cell counting method				0					60517	527
FHH-Tlr4m1Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	9			18.04	pg	0.14	0.42	automated blood cell counting method				0					60522	527
SS-Klf4m3Mcwi	serum total cholesterol level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood cholesterol amount	female	70 days-84 days	7			86.29	mg/dl	18.04	47.74	standard blood chemistry panel				0					60535	527
FHH-Adipoqm2Mcwi	red blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	female	70 days-84 days	12			7.49	x 10E6 cells/ul	0.54	1.88	automated blood cell counting method				0					60543	527
FHH-Ccr2m1Mcwi	red blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	male	70 days-84 days	8			8.97	x 10E6 cells/ul	0.34	0.96	automated blood cell counting method				0					60570	527
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi	red blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	female	70 days-84 days	7			8.01	x 10E6 cells/ul	0.19	0.5	automated blood cell counting method				0					60573	527
FHH-F10m2Mcwi	red blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	female	70 days-84 days	12			7.6	x 10E6 cells/ul	0.15	0.51	automated blood cell counting method				0					60577	527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi	red blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	female	70 days-84 days	2			8.1	x 10E6 cells/ul	0.24	0.34	automated blood cell counting method				0					60588	527
BN-Lcatm3Mcwi	red blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	female	70 days-84 days	2			8.45	x 10E6 cells/ul	0.14	0.2	automated blood cell counting method				0					60586	527
BN-Lcatm3Mcwi	red blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	male	70 days-84 days	1			8.01	x 10E6 cells/ul			automated blood cell counting method				0					60589	527
FHH-Adra1am1Mcwi	red blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	female	70 days-84 days	9			7.84	x 10E6 cells/ul	0.18	0.53	automated blood cell counting method				0					60599	527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi	red blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	male	70 days-84 days	3			8.86	x 10E6 cells/ul	0.4	0.69	automated blood cell counting method				0					60601	527
SS-Wdr72em1Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	1			1.41	g			digital scale post excision weight measurement				0				-	44340	441
SS-Plekha7em4Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	12			1.33	g	0.05	0.16	digital scale post excision weight measurement				0				-	44347	441
SS-Prokr1em2Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	8			1.5	g	0.04	0.11	digital scale post excision weight measurement				0				-	44349	441
SS-Plekha7em1Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	9			1.41	g	0.04	0.12	digital scale post excision weight measurement				0				-	44350	441
SS-Nppbem4Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	8			1.44	g	0.02	0.05	digital scale post excision weight measurement				0				-	44352	441
SS-Prokr1em1Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	5			1.46	g	0.04	0.08	digital scale post excision weight measurement				0				-	44353	441
SS/JrHsdMcwi	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	7			1.61	g	0.05	0.13	digital scale post excision weight measurement				0				-	44364	441
SS-Stk39em2Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	10			1.33	g	0.02	0.06	digital scale post excision weight measurement				0				-	44370	441
SS-Msraem3Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	3			1.6	g	0.07	0.12	digital scale post excision weight measurement				0				-	44378	441
SS-Nppbem2Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	1/3 systolic pressure + 2/3 diastolic pressure		133.25	mmHg	3.68	7.37	radiotelemetry	carotid artery			0				-	44390	441
SS-Msraem4Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	5	1/3 systolic pressure + 2/3 diastolic pressure		126.0	mmHg	8.75	19.57	radiotelemetry	carotid artery			0				-	44391	441
SS-Plekha7em4Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		155.5	mmHg	10.5	14.85	radiotelemetry	carotid artery			0				-	44407	441
SS-Plekha7em4Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	11	1/3 systolic pressure + 2/3 diastolic pressure		135.64	mmHg	6.09	20.19	radiotelemetry	carotid artery			0				-	44409	441
SS-Sh2b3em2Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	7	1/3 systolic pressure + 2/3 diastolic pressure		147.14	mmHg	7.95	21.03	radiotelemetry	carotid artery			0				-	44423	441
SS-Tcf7l2em1Mcwi-/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		150.0	mmHg	2.0	2.83	radiotelemetry	carotid artery			0				-	44430	441
SS-Agtrapem8Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		122.0	mmHg	4.0	5.66	radiotelemetry	carotid artery			0				-	44428	441
SS-Stk39em2Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	10	1/3 systolic pressure + 2/3 diastolic pressure		126.2	mmHg	4.07	12.87	radiotelemetry	carotid artery			0				-	44431	441
SS-Agtr1aem1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	9	1/3 systolic pressure + 2/3 diastolic pressure		131.89	mmHg	4.34	13.02	radiotelemetry	carotid artery			0				-	44434	441
SS-Plekha7em4Mcwi+/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	2			1.53	g	0.04	0.06	digital scale post excision weight measurement				0				-	44468	441
SS-Plod1em1Mcwi-/-	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	11			1.49	g	0.06	0.18	digital scale post excision weight measurement				0				-	44471	441
SS-Plcd3em7Mcwi-/-	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	10			1.41	g	0.05	0.17	digital scale post excision weight measurement				0				-	44481	441
SS/JrHsdMcwi	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	7			1.58	g	0.06	0.15	digital scale post excision weight measurement				0				-	44487	441
SS-Tcf7l2em1Mcwi-/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	2			1.57	g	0.04	0.06	digital scale post excision weight measurement				0				-	44492	441
SS-Wdr72em1Mcwi+/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	2			1.56	g	0.08	0.11	digital scale post excision weight measurement				0				-	44489	441
SS-Agtrapem8Mcwi+/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	2			1.46	g	0.01	0.02	digital scale post excision weight measurement				0				-	44490	441
SS-Mstnem1Mcwi+/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	3			1.67	g	0.06	0.11	digital scale post excision weight measurement				0				-	44498	441
SS-Nppaem4Mcwi+/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	2			1.37	g	0.02	0.03	digital scale post excision weight measurement				0				-	44502	441
SS-Nppbem4Mcwi+/+	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	9			1.13	g	0.04	0.12	digital scale post excision weight measurement				0				-	44515	441
SS-Ulk3em1Mcwi-/-	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	11			1.09	g	0.02	0.07	digital scale post excision weight measurement				0				-	44526	441
SS-Cyp1a1em1Mcwi+/+	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	3			1.09	g	0.06	0.1	digital scale post excision weight measurement				0				-	44527	441
SS-Plcd3em4Mcwi-/-	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	13			1.1	g	0.02	0.05	digital scale post excision weight measurement				0				-	44531	441
SS-Plekha7em4Mcwi-/-	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	13			1.04	g	0.03	0.12	digital scale post excision weight measurement				0				-	44532	441
SS-Prokr1em1Mcwi-/-	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	5			1.12	g	0.04	0.09	digital scale post excision weight measurement				0				-	44538	441
SS-Plod1em1Mcwi-/-	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	12			1.14	g	0.03	0.09	digital scale post excision weight measurement				0				-	44533	441
SS-Aldh2em2Mcwi+/+	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	6			1.19	g	0.05	0.11	digital scale post excision weight measurement				0				-	44544	441
SS-Stk39em2Mcwi-/-	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	10			0.96	g	0.03	0.11	digital scale post excision weight measurement				0				-	44555	441
SS-Slc30a8em2Mcwi-/-	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	9			1.2	g	0.02	0.06	digital scale post excision weight measurement				0				-	44562	441
SS-Kcnq1em14Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	7			350.29	beats/min	11.7	30.96	radiotelemetry	carotid artery			0				-	44572	441
SS-Agtrapem8Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	7			361.97	beats/min	9.06	23.96	radiotelemetry	carotid artery			0				-	44578	441
SS-Msraem4Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	6			358.83	beats/min	17.96	43.99	radiotelemetry	carotid artery			0				-	44581	441
SS-Stk39em2Mcwi-/+	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	1			373.0	beats/min			radiotelemetry	carotid artery			0				-	44585	441
SS-Mstnem3Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			341.0	beats/min	13.0	18.38	radiotelemetry	carotid artery			0				-	44586	441
SS-Ulk3em1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	10			362.9	beats/min	6.43	20.34	radiotelemetry	carotid artery			0				-	44588	441
SS-Plcd3em4Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	11			338.73	beats/min	9.57	31.74	radiotelemetry	carotid artery			0				-	44593	441
SS-Plekha7em4Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	12			378.33	beats/min	7.67	26.58	radiotelemetry	carotid artery			0				-	44594	441
SS-Prokr1em2Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	7			364.0	beats/min	4.74	12.54	radiotelemetry	carotid artery			0				-	44596	441
SS-Plcd3em7Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	8			354.5	beats/min	6.26	17.7	radiotelemetry	carotid artery			0				-	44605	441
SS-Tcf7l2em1Mcwi-/+	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			378.5	beats/min	5.5	7.78	radiotelemetry	carotid artery			0				-	44615	441
SS-Nppbem2Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	14			354.71	beats/min	6.54	24.45	radiotelemetry	carotid artery			0				-	44617	441
SS-Kcnq1em14Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	1			380.0	beats/min			radiotelemetry	carotid artery			0				-	44626	441
SS-Tcf7l2em1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	9			364.33	beats/min	7.03	21.08	radiotelemetry	carotid artery			0				-	44620	441
SS-Mstnem3Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			321.5	beats/min	22.5	31.82	radiotelemetry	carotid artery			0				-	44647	441
SS-Msraem4Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	6			379.5	beats/min	16.45	40.3	radiotelemetry	carotid artery			0				-	44642	441
SS-Tcf7l2em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	5			369.6	beats/min	15.17	33.93	radiotelemetry	carotid artery			0				-	44645	441
SS-Cyp1a1em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	3			402.33	beats/min	8.41	14.57	radiotelemetry	carotid artery			0				-	44650	441
SS-Plekha7em4Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	11			385.73	beats/min	6.12	20.31	radiotelemetry	carotid artery			0				-	44655	441
SS-Aldh2em2Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	7			370.0	beats/min	6.38	16.87	radiotelemetry	carotid artery			0				-	44663	441
SS-Plcd3em7Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	9			363.89	beats/min	9.64	28.93	radiotelemetry	carotid artery			0				-	44666	441
SS-Agtrapem8Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			365.5	beats/min	0.5	0.71	radiotelemetry	carotid artery			0				-	44674	441
SS-Slc30a8em1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	8			363.13	beats/min	7.1	20.07	radiotelemetry	carotid artery			0				-	44679	441
SS-Msraem3Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	3			375.33	beats/min	30.07	52.08	radiotelemetry	carotid artery			0				-	44685	441
SS.LEW-(D10Wox51-D10Rat27)/Ayd	mean arterial blood pressure	controlled sodium content diet (2 %) (for 21 days)	Charron S, et al., Hypertension. 2005 Dec;46(6):1300-8. Epub 2005 Nov 14.	arterial blood pressure trait	male	56 days-59 days	5			140.0	mmHg			intra-aortic abdominal radiotelemetry		86400.0		0					67878	830
SS.LEW-(D5Mco39-D5Mco57)(D5Mco42-D5Mco47)/Mco	systolic blood pressure	controlled sodium content diet (2 %) (between 24 and 28 days)	Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11.	arterial blood pressure trait	male	62 days-66 days	0			226.0	mmHg	5.5		tail cuff plethysmography		0.0		0		restrained, 28 degrees C			70586	1482
SS.LEW-(D5Mco41-D5Mco47)/Mco	systolic blood pressure	controlled sodium content diet (2 %) (between 24 and 28 days)	Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11.	arterial blood pressure trait	male	62 days-66 days	0			204.0	mmHg	5.4		tail cuff plethysmography		0.0		0		restrained, 28 degrees C			70591	1482
SS/JrHsd	systolic blood pressure	controlled sodium content diet (8 %) (between 83 and 84 days)	Herrera VL, et al., Physiol Genomics. 2006 Aug 16;26(3):172-9. Epub 2006 May 23.	arterial blood pressure trait	female	167 days-168 days	8			199.5	mmHg	6.93	19.6	intra-aortic abdominal radiotelemetry		0.0		0					67857	810
SR/JrHsd	heart weight to body weight ratio	controlled sodium content diet (8 %) (for 84 days)	Herrera VL, et al., Physiol Genomics. 2006 Aug 16;26(3):172-9. Epub 2006 May 23.	heart mass	female	168 days	5			2.37	g/kg	0.04	0.09	post excision weight measurement		0.0		0					67867	810
SS/JrHsd	heart weight to body weight ratio	controlled sodium content diet (8 %) (for 56 days)	Herrera VL, et al., Physiol Genomics. 2006 Aug 16;26(3):172-9. Epub 2006 May 23.	heart mass	male	140 days	6			3.31	g/kg	0.13	0.32	post excision weight measurement		0.0		0					67866	810
SS.LEW-(D8Chm14-D8Rat16)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days)	Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.	arterial blood pressure trait	male	66 days-80 days	7			138.0	mmHg	5.0	13.23	intra-aortic abdominal radiotelemetry	abdominal aorta	0.0		0					70441	1438
SS.LEW-(D2Rat199-D2Mco17)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days)	Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.	arterial blood pressure trait	male	66 days-80 days	8			199.0	mmHg	4.0	11.31	intra-aortic abdominal radiotelemetry	abdominal aorta	0.0		0					70446	1438
SS.LEW-(D10Rat194-D10Chm243)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days)	Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.	arterial blood pressure trait	male	66 days-80 days	11			144.0	mmHg	2.0	6.63	intra-aortic abdominal radiotelemetry	abdominal aorta	0.0		0					70450	1438
SS.MNS-(D2Mit6-D2Rat166)/Ayd	heart right ventricle deoxyribonucleic acid level to body weight ratio	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days)	Dutil J, et al., Physiol Genomics 2005 Mar 1;.	heart right ventricle DNA amount	male	98 days	4			0.5	ug/g	0.09	0.18	spectrophotometry		0.0		0					69041	1096
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb	percentage of study population developing cerebrovascular lesions during a period of time	controlled sodium content diet (3.7 mg/g) (between 28 and 49 days) and controlled sodium content drinking water (1 %) (between 28 and 49 days) and controlled potassium content diet (6.3 mg/g) (between 28 and 49 days)	Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11.	cerebrovascular system integrity trait	not specified	70 days-91 days	20			61.0	%			ex vivo light microscopy		0.0		0					69121	1126
SS/JrSeac	heart left ventricle relative wall thickness	controlled sodium content diet (8 %) (for 35 days)	Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1.	heart left ventricle wall thickness	not specified	77 days	5	RWT = 2 × PWT/EDD		86.0	%	16.55	37.0	transthoracic echocardiography		0.0		0					68588	733
SS/JrSeac	heart left ventricle relative wall thickness	controlled sodium content diet (0.3 %) (for 35 days)	Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1.	heart left ventricle wall thickness	not specified	77 days	5	RWT = 2 × PWT/EDD		44.0	%	7.16	16.0	transthoracic echocardiography		0.0		0					68587	733
SS/JrSeac	heart left ventricle relative wall thickness	controlled sodium content diet (8 %) (for 84 days)	Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1.	heart left ventricle wall thickness	not specified	126 days	5	RWT = 2 × PWT/EDD		29.0	%	5.81	13.0	transthoracic echocardiography		0.0		0					68590	733
SS/JrSeac	heart rate	controlled sodium content diet (8 %) (for 84 days) then controlled oxygen content Kreb's solution perfusate	Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1.	heart pumping trait	not specified	126 days	5			284.0	beats/min	58.58	131.0	isolated perfused heart method		0.0		0					68594	733
SS/JrSeac	heart rate	controlled sodium content diet (0.3 %) (for 35 days) then controlled oxygen content Kreb's solution perfusate	Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1.	heart pumping trait	not specified	77 days	5			264.0	beats/min	37.12	83.0	isolated perfused heart method		0.0		0					68591	733
SS/JrHsdMcwi	mean arterial blood pressure	furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then angiotensin II (100 ng/kg/min) (for 0.1 hours)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	arterial blood pressure trait	female	101 days-103 days	13		serial mean	147.2	mmHg	3.9	14.06	vascular indwelling catheter method	left femoral artery	120.0		0					69532	151
BN/NHsdMcwi	mean arterial blood pressure	furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then norepinephrine (0.5 ug/kg/min) (for 0.1 hours)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	arterial blood pressure trait	female	101 days-103 days	21		serial mean	120.4	mmHg	5.3	24.29	vascular indwelling catheter method	left femoral artery	120.0		0					69535	151
SS/JrHsdMcwi	mean arterial blood pressure	furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then angiotensin II (20 ng/kg/min) (for 0.1 hours)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	arterial blood pressure trait	female	101 days-103 days	13		serial mean	131.3	mmHg	4.2	15.14	vascular indwelling catheter method	left femoral artery	120.0		0					69530	151
BN/NHsdMcwi	mean arterial blood pressure	furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then acetylcholine (0.1 ug/kg/min) (for 0.1 hours)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	arterial blood pressure trait	female	101 days-103 days	21		serial mean	111.3	mmHg	4.6	21.08	vascular indwelling catheter method	left femoral artery	120.0		0					69541	151
SS/JrHsdMcwi	mean arterial blood pressure	furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then NG-nitroarginine methyl ester (5 mg/kg)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	arterial blood pressure trait	female	101 days-103 days	9		serial mean	159.0	mmHg	7.1	21.3	vascular indwelling catheter method	left femoral artery	120.0		0					69546	151
SS.LEW-(D16Rat112-D16Chm60)/Ayd	heart left ventricle anterior wall thickness	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	heart left ventricle anterior wall thickness	male	77 days	14			0.17	mm	0.0	0.01	transthoracic echocardiography		0.0		0					68254	542
SS.LEW-(D3Rat52-D3Chm57)/Ayd	heart left ventricle anterior wall thickness	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	heart left ventricle anterior wall thickness	male	77 days	8			0.17	mm	0.0	0.01	transthoracic echocardiography		0.0		0					68256	542
SS.LEW-(D18Rat29-D18Rat55)/Ayd	heart left ventricle weight to body weight ratio	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	heart left ventricle mass	male	77 days	11			2.75	mg/g	0.11	0.37	post excision weight measurement		0.0		0					68259	542
SS.LEW-(D16Rat112-D16Chm60)/Ayd	heart left ventricle weight to body weight ratio	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	heart left ventricle mass	male	77 days	14			2.67	mg/g	0.08	0.31	post excision weight measurement		0.0		0					68262	542
SS/Jr	heart left ventricle end-systolic area	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	heart left ventricle size trait	not specified	0 days	6			0.25	cm2	0.07	0.17	echocardiography		0.0		0					69602	749
SS/Jr	heart left ventricle posterior wall thickness	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	heart left ventricle posterior wall thickness	not specified	0 days	6			2.9	mm	0.3	0.73	echocardiography		0.0		0					69604	749
SS/Jr	age at time of death	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 66 and 68 days)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	total life span	not specified	0 days	8		median	108.0	d			necropsy		0.0		0		visual observation			69608	749
SS/JrHsd	pulse pressure	controlled sodium content diet (8 %) (between 24 and 28 days)	Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013.	arterial blood pressure trait	male	108 days-112 days	8			57.1	mmHg	0.4	1.13	intra-aortic abdominal radiotelemetry		0.0		0					70504	1458
SS/JrHsd	diastolic blood pressure	controlled sodium content diet (8 %) (between 24 and 28 days)	Herrera VL, et al., PLoS One. 2012;7(7):e42214. doi: 10.1371/journal.pone.0042214. Epub 2012 Jul 30.	arterial blood pressure trait	female	108 days-112 days	9			139.7	mmHg	5.8	17.4	intra-aortic abdominal radiotelemetry		0.0		0					70354	1358
SS.SR-(rs65785750-rs13452155)/Opaz	diastolic blood pressure	controlled sodium content diet (8 %) (between 24 and 28 days)	Herrera VL, et al., PLoS One. 2012;7(7):e42214. doi: 10.1371/journal.pone.0042214. Epub 2012 Jul 30.	arterial blood pressure trait	female	108 days-112 days	10			131.9	mmHg	3.6	11.38	intra-aortic abdominal radiotelemetry		0.0		0					70355	1358
SS.SR-(rs65785750-rs13452155)/Opaz	mean arterial blood pressure	controlled sodium content diet (8 %) (between 24 and 28 days)	Herrera VL, et al., PLoS One. 2012;7(7):e42214. doi: 10.1371/journal.pone.0042214. Epub 2012 Jul 30.	arterial blood pressure trait	female	108 days-112 days	10			157.7	mmHg	3.7	11.7	intra-aortic abdominal radiotelemetry		0.0		0					70358	1358
SHRSP/Bbb	urine total protein excretion rate	controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days)	Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11.	total urine protein amount	not specified	56 days	31			35.0	mg/d	0.61	3.4	Bradford protein assay		0.0		0					69216	1126
SHRSP/Bbb	urine total protein excretion rate	controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days)	Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11.	total urine protein amount	not specified	70 days	26			215.0	mg/d	18.43	94.0	Bradford protein assay		0.0		0					69217	1126
SS/JrHsdMcwi	urine sodium level	controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	urine sodium amount	female	92 days-94 days	14			149.5	mmol/l	5.2	19.46	unspecified method		0.0		0		urine sodium analysis			69467	151
SS/JrHsdMcwi	hematocrit	controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	erythrocyte quantity	female	89 days-92 days	15			38.8	%	1.4	5.42	hematocrit analysis		0.0		0					69482	151
SS.SR-(rs106870553-rs63922710)/Opaz	systolic blood pressure	controlled sodium content diet (8 %) (between 24 and 28 days)	Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013.	arterial blood pressure trait	female	108 days-112 days	10			187.0	mmHg	3.0	9.49	intra-aortic abdominal radiotelemetry		0.0		0					70566	1458
LEW	heart left ventricle end-systolic diameter	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	heart left ventricle end-systolic diameter	male	77 days	14			3.69	mm	0.16	0.6	transthoracic echocardiography		0.0		0			heart left ventricle anterior wall thickness		68273	542
SS.LEW-(D16Rat112-D16Chm60)/Ayd	heart left ventricle end-systolic diameter	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	heart left ventricle end-systolic diameter	male	77 days	14			3.77	mm	0.15	0.57	transthoracic echocardiography		0.0		0					68278	542
SS.LEW-(D16Chm36-D16Mit2)/Ayd	heart left ventricle fractional shortening	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	heart left ventricle end-diastolic diameter	male	77 days	18	(LVDdLVDs)/LVDd x 100		44.1	%	1.38	5.87	transthoracic echocardiography		0.0		0					68285	542
SS.LEW-(D16Rat112-D16Chm60)/Ayd	heart left ventricle fractional shortening	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	heart left ventricle end-diastolic diameter	male	77 days	14	(LVDdLVDs)/LVDd x 100		50.0	%	1.51	5.66	transthoracic echocardiography		0.0		0					68286	542
SS.LEW-(D16Rat112-D16Chm60)/Ayd	ejection fraction	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	cardiac output trait	male	77 days	14			85.3	%	1.39	5.21	transthoracic echocardiography		0.0		0			peak aortic velocity		68294	542
SS/NEisSlc	systolic blood pressure	controlled sodium content diet (8 %) (for 28 days) then adrenalectomy then controlled sodium content diet (0.3 %) (for 28 days) and dexamethasone (20 ug/d)	Kitada K, et al., PLoS One. 2012;7(7):e41896. Epub 2012 Jul 24.	arterial blood pressure trait	male	98 days	4			141.0	mmHg	8.0	16.0	tail cuff plethysmography		0.0		0					69688	736
SHRSR.SHRSP-(Klk1-D1Mit3)/Bbb	urine total protein excretion rate	controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days)	Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11.	total urine protein amount	not specified	70 days	31			74.0	mg/d	2.69	15.0	Bradford protein assay		0.0		0					70244	1126
SHRSR.SHRSP-(Klk1-D1Mit3)/Bbb	urine total protein excretion rate	controlled sodium content diet (3.7 mg/g) (for 84 days) and controlled sodium content drinking water (1 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days)	Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11.	total urine protein amount	not specified	126 days	31			58.0	mg/d	1.33	7.4	Bradford protein assay		0.0		0					70248	1126
SS.LEW-(D10Chm10-D10Rat11)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days)	Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.	arterial blood pressure trait	male	66 days-80 days	7			150.0	mmHg	3.0	7.94	intra-aortic abdominal radiotelemetry	abdominal aorta	0.0		0					70436	1438
SS/JrSeac	myocardial flow rate	controlled sodium content diet (8 %) (for 35 days) then controlled oxygen content Kreb's solution perfusate (for 0.2 hours) then 99mTc-sestamibi (37 MBq/l) (for 0.3 hours) then controlled oxygen content Kreb's solution perfusate (for 0.4 hours)	Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1.	coronary blood flow trait	not specified	77 days	5			2.36	ml/min	0.48	1.07	isolated perfused heart method		0.0		0			K1, myocardial flow rate		68596	733
SS/JrSeac	myocardial clearance rate	controlled sodium content diet (0.3 %) (for 35 days) then controlled oxygen content Kreb's solution perfusate (for 0.2 hours) then 99mTc-sestamibi (37 MBq/l) (for 0.3 hours) then Kreb's solution perfusate (for 0.4 hours)	Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1.	heart muscle physiology trait	not specified	77 days	5			0.0	/min	0.0	0.0	isolated perfused heart method		0.0		0			K2, myocardial clearance rate		68599	733
SS/JrSeac	myocardial flow rate	controlled sodium content diet (0.3 %) (for 35 days) then controlled oxygen content Kreb's solution perfusate (for 0.2 hours) then 99mTc-sestamibi (37 MBq/l) (for 0.3 hours) then controlled oxygen content Kreb's solution perfusate (for 0.4 hours)	Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1.	coronary blood flow trait	not specified	126 days	5			2.84	ml/min	0.25	0.57	isolated perfused heart method		0.0		0			K1, myocardial flow rate		68597	733
SS.MNS-(Mme-D2Rat131)/Ayd	heart left ventricle deoxyribonucleic acid level to body weight ratio	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days)	Dutil J, et al., Physiol Genomics 2005 Mar 1;.	heart left ventricle DNA amount	male	98 days	5			3.7	ug/g	0.3	0.67	spectrophotometry		0.0		0					69038	1096
BN/NHsdMcwi	systolic blood pressure	controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	arterial blood pressure trait	female	92 days	20		serial mean	140.6	mmHg	4.4	19.68	vascular indwelling catheter method	left femoral artery	10800.0		0					69509	151
BN/NHsdMcwi	heart rate	controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	heart pumping trait	female	94 days	16		serial mean	370.1	beats/min	6.3	25.2	vascular indwelling catheter method	left femoral artery	10800.0		0					69525	151
LEW/Crlc	cerebrospinal fluid chloride level	controlled sodium content diet (8 %) (between 8 and 10 days)	Huang BS, et al., Hypertension. 2007 Apr 9;.	cerebrospinal fluid mineral amount	male	43 days-52 days	0			121.0	mmol/l	1.0		chloride ion-selective electrode method		0.0		0					69694	344
SS/JrHsd	diastolic blood pressure	controlled sodium content diet (8 %) (between 83 and 84 days)	Herrera VL, et al., Physiol Genomics. 2006 Aug 16;26(3):172-9. Epub 2006 May 23.	arterial blood pressure trait	female	167 days-168 days	8			143.0	mmHg	4.88	13.8	intra-aortic abdominal radiotelemetry		0.0		0					67871	810
SHRSR.SHRSP-(Klk1-Mt1-ps1)/Bbb	systolic blood pressure	controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days)	Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11.	arterial blood pressure trait	not specified	56 days	33			148.0	mmHg	3.13	18.0	tail cuff plethysmography		0.0		0					69166	1126
SHRSR.SHRSP-(Klk1-D1Mit3)/Bbb	systolic blood pressure	controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days)	Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11.	arterial blood pressure trait	not specified	56 days	31			146.0	mmHg	1.26	7.0	tail cuff plethysmography		0.0		0					69173	1126
SHRSR.SHRSP-(Klk1-D1Mit3)/Bbb	systolic blood pressure	controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days)	Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11.	arterial blood pressure trait	not specified	70 days	31			176.0	mmHg	1.89	10.5	tail cuff plethysmography		0.0		0					69174	1126
SHRSR.SHRSP-(Klk1-D1Mit3)/Bbb	systolic blood pressure	controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days)	Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11.	arterial blood pressure trait	not specified	84 days	31			181.0	mmHg	1.65	9.2	tail cuff plethysmography		0.0		0					69175	1126
SHRSR.SHRSP-(Klk1-D1Mit3)/Bbb	systolic blood pressure	controlled sodium content diet (3.7 mg/g) (for 84 days) and controlled sodium content drinking water (1 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days)	Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11.	arterial blood pressure trait	not specified	126 days	31			208.0	mmHg	1.44	8.0	tail cuff plethysmography		0.0		0					69178	1126
SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb	systolic blood pressure	controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days)	Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11.	arterial blood pressure trait	not specified	84 days	31			191.0	mmHg	0.72	4.0	tail cuff plethysmography		0.0		0					69182	1126
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb	systolic blood pressure	controlled sodium content diet (3.7 mg/g) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days)	Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11.	arterial blood pressure trait	not specified	98 days	3			195.0	mmHg	2.89	5.0	tail cuff plethysmography		0.0		0					69190	1126
SHRSP.SHRSR-(D1Rat134-Mt1-ps1)/Bbb	systolic blood pressure	controlled sodium content diet (3.7 mg/g) (for 70 days) and controlled sodium content drinking water (1 %) (for 70 days) and controlled potassium content diet (6.3 mg/g) (for 70 days)	Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11.	arterial blood pressure trait	not specified	112 days	5			198.0	mmHg	1.34	3.0	tail cuff plethysmography		0.0		0					69200	1126
SS/JrHsdMcwi	thymus wet weight	controlled sodium content diet (4 %) (for 21 days)	Mattson DL, et al., Am J Physiol Regul Integr Comp Physiol. 2013 Jan 30.	thymus mass	not specified	84 days	4			500.0	mg	100.0	200.0	post excision weight measurement		0.0		0					69289	1057
SS	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days)	Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.	arterial blood pressure trait	male	66 days-80 days	12			183.0	mmHg	4.0	13.86	intra-aortic abdominal radiotelemetry	abdominal aorta	0.0		0					70469	1438
SS/JrHsdMcwi	systolic blood pressure	controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) then controlled exposure to darkness (for 12 hours)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	arterial blood pressure trait	female	89 days-91 days	15		serial mean	184.0	mmHg	7.7	29.82	vascular indwelling catheter method	left femoral artery	0.0		0					69444	151
BN/NHsdMcwi	urine creatinine level	controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	urine creatinine amount	female	89 days-92 days	24			30.2	mg/dl	3.87	18.96	urine creatinine analysis		0.0		0					69455	151
BN/NHsdMcwi	urine sodium excretion rate	controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	urine sodium amount	female	89 days-92 days	24			6.35	mEq/d	0.35	1.74	unspecified method		0.0		0		urine sodium analysis	umol/min		69459	151
SS/JrHsdMcwi	urine sodium excretion rate	controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	urine sodium amount	female	89 days-92 days	17			5.06	mEq/d	0.6	2.49	unspecified method		0.0		0		urine sodium analysis	umol/min		69460	151
SS/JrTol	systolic blood pressure	controlled sodium content diet (2 %) (between 24 and 28 days)	Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11.	arterial blood pressure trait	male	62 days-66 days	0			196.0	mmHg	6.8		tail cuff plethysmography		0.0		0		restrained, 28 degrees C			70583	1482
SS.LEW-(D18Chm90-D18Chm4)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 12 days)	Chauvet C, et al., J Hypertens. 2011 Jul;29(7):1320-6. doi: 10.1097/HJH.0b013e32834705e4.	arterial blood pressure trait	male	68 days	5		serial mean	170.0	mmHg	8.0	17.89	radiotelemetry	abdominal aorta	1036800.0		0		telemetry probe	averaged over 12 days	has records that will be duplicated if entered need to add multiple refs once the functionality is in	96572	1663
SS-Chr 12BN/Mcwi	artery wall thickness to artery inner diameter ratio	controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (40 mmHg)	Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22.	mesenteric artery morphology trait	male	63 days-70 days	7			17.2	%	0.6	1.59	unspecified method		0.0		0				mesenteric artery morphology trait	96874	1719
SS-Chr 12BN/Mcwi	artery wall thickness to artery inner diameter ratio	controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (100 mmHg)	Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22.	mesenteric artery morphology trait	male	63 days-70 days	7			9.4	%	0.5	1.32	unspecified method		0.0		0				mesenteric artery morphology trait	96877	1719
SS-Chr 12BN/Mcwi	artery wall thickness to artery inner diameter ratio	controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (80 mmHg)	Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22.	mesenteric artery morphology trait	male	63 days-70 days	7			10.8	%	0.6	1.59	unspecified method		0.0		0				mesenteric artery morphology trait	96876	1719
SS.LEW-(D10Chm10-D10Rat11)(D16Chm48-D16Chm60)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days)	Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.	arterial blood pressure trait	male	66 days-80 days	8			137.0	mmHg	3.0	8.49	intra-aortic abdominal radiotelemetry	abdominal aorta	0.0		0					84488	1438
SS.LEW-(D16Chm48-D16Chm60)(D18Rat101-D18Rat92)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days)	Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.	arterial blood pressure trait	male	66 days-80 days	5			141.0	mmHg	4.0	8.94	intra-aortic abdominal radiotelemetry	abdominal aorta	0.0		0					84498	1438
SS.MNS-(D2Chm33-Tm2sf1),LEW-(D3Rat2-D3Chm79)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days)	Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.	arterial blood pressure trait	male	66 days-80 days	9			117.0	mmHg	2.0	6.0	intra-aortic abdominal radiotelemetry	abdominal aorta	0.0		0					84511	1438
SHRSP.SHRSR-(D1Rat134-Mt1-ps1)/Bbb	urine total protein excretion rate	controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days)	Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11.	total urine protein amount	not specified	56 days	35			24.0	mg/d	1.86	11.0	Bradford protein assay		0.0		0					84582	1126
SHRSP.SHRSR-(D1Rat134-Mt1-ps1)/Bbb	urine total protein excretion rate	controlled sodium content diet (3.7 mg/g) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days)	Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11.	total urine protein amount	not specified	98 days	14			343.0	mg/d	16.04	60.0	Bradford protein assay		0.0		0					84585	1126
ACI.FHH-(D1Mit18-D1Rat90)(D3Rat6-D3Got149)(D14Mit11-D14Rat33)(D14Rat65-D14Rat90)/Mcwi	urine albumin excretion rate	right nephrectomy (for 28 days) then controlled sodium content diet (0.4 %) (for 28 days)	O'Meara CC, et al., J Am Soc Nephrol. 2011 Mar;22(3):518-25. Epub 2010 Dec 2.	urine albumin amount	male	63 days-70 days	13			15.4	mg/d	2.4	8.65	fluorometry		0.0	right nephrectomy	28	days				84747	1600
ACI.FHH-(D1Mit18-D1Rat90)(D14Mit11-D14Rat33)(D14Rat65-D14Rat90)/Eur	urine albumin excretion rate	right nephrectomy (for 28 days) then controlled sodium content diet (0.4 %) (for 28 days)	O'Meara CC, et al., J Am Soc Nephrol. 2011 Mar;22(3):518-25. Epub 2010 Dec 2.	urine albumin amount	male	63 days-70 days	9			11.18	mg/d	3.18	9.54	fluorometry		0.0	right nephrectomy	28	days				84748	1600
ACI.FHH-(D1Mit18-D1Rat90)(D3Rat6-D3Got149)(D14Mit11-D14Rat33)(D14Rat65-D14Rat90)/Mcwi	ratio of the area occupied by protein casts to the total area of the kidney outer medulla outer stripe and cortex	right nephrectomy (for 42 days) then controlled sodium content diet (0.4 %) (for 42 days)	O'Meara CC, et al., J Am Soc Nephrol. 2011 Mar;22(3):518-25. Epub 2010 Dec 2.	kidney integrity trait	male	84 days	3			1.18	%	0.26	0.45	ex vivo light microscopy with digital image analysis		0.0		42	days		area of cast to kidney area ratio		84750	1600
SS.MNS-(D2Chm153-D2Chm410)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 12 days)	Chauvet C, et al., Hypertens Res. 2009 Jul;32(7):631-7. doi: 10.1038/hr.2009.70. Epub 2009 May 22.	arterial blood pressure trait	male	68 days	6		serial mean	141.0	mmHg	6.0	14.7	radiotelemetry		1036800.0		0		telemetry probe	averaged over 12 days	has records that will be duplicated if entered need to add multiple refs once the functionality is in	96576	1664
SS-Chr 12BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi	mean arterial blood pressure	controlled sodium content diet (1 %) (between 42 and 49 days)	Prisco SZ, et al., Hypertension. 2014 Jul 7. pii: HYPERTENSIONAHA.114.03550.	arterial blood pressure trait	male	71 days-77 days	14			110.0	mmHg	2.0	7.48	intra-aortic abdominal radiotelemetry		0.0		0					96801	1698
SS-Chr 12BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi	artery wall thickness to artery inner diameter ratio	controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (160 mmHg)	Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22.	mesenteric artery morphology trait	male	63 days-70 days	5			6.3	%	0.3	0.67	unspecified method		0.0		0				mesenteric artery morphology trait	96888	1719
SS-Chr 12BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi	artery wall thickness to artery inner diameter ratio	controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (140 mmHg)	Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22.	mesenteric artery morphology trait	male	63 days-70 days	5			6.5	%	0.3	0.67	unspecified method		0.0		0				mesenteric artery morphology trait	96887	1719
SS.BN-(D12Hmgc3-AU047911)/Mcwi	artery wall thickness to artery inner diameter ratio	controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (60 mmHg)	Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22.	mesenteric artery morphology trait	male	63 days-70 days	12			12.2	%	0.5	1.73	unspecified method		0.0		0				mesenteric artery morphology trait	96891	1719
SS.BN-(D12Hmgc3-AU047911)/Mcwi	artery wall thickness to artery inner diameter ratio	controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (140 mmHg)	Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22.	mesenteric artery morphology trait	male	63 days-70 days	12			7.5	%	0.3	1.04	unspecified method		0.0		0				mesenteric artery morphology trait	96895	1719
SHR-Ndufc2em2Mcwi+/+	body weight	controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days)	Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701.	body mass	not specified	70 days	12			239.0	g	3.75	13.0	body weighing method		0.0		0					97900	1938
SHR-Ndufc2em2Mcwi+/+	body weight	controlled protein content diet (19.7 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) and controlled sodium content diet (3.7 mg/g) (for 56 days)	Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701.	body mass	not specified	98 days	12			299.0	g	4.62	16.0	body weighing method		0.0		0					97901	1938
SHR-Ndufc2em2Mcwi-/+	body weight	controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days)	Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701.	body mass	not specified	70 days	26			237.0	g	5.3	27.0	body weighing method		0.0		0					97903	1938
SHR/Bbb	body weight	controlled protein content diet (19.7 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) and controlled sodium content diet (3.7 mg/g) (for 84 days)	Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701.	body mass	not specified	126 days	18			289.0	g	1.89	8.0	body weighing method		0.0		0					97908	1938
SHRSP/Bbb	body weight	controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days)	Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701.	body mass	not specified	70 days	18			177.0	g	1.41	6.0	body weighing method		0.0		0					97909	1938
SHR-Ndufc2em1Mcwi+/+	body weight	controlled protein content diet (19.7 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) and controlled sodium content diet (3.7 mg/g) (for 56 days)	Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701.	body mass	not specified	98 days	10			287.0	g	3.79	12.0	body weighing method		0.0		0					97878	1938
SS.LEW-(D1Mco55-D1Wox6)/Bj	mean arterial blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days)	Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18.	arterial blood pressure trait	male	73 days-75 days	10			128.0	mmHg	6.0	18.97	radiotelemetry		345600.0		0		C-40 transmitter (Data Sciences International, St. Paul, MN)	average of 24 hour		96960	1778
SS/JrTol	body weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18.	body mass	male	73 days-75 days	10			338.0	g	4.0	12.65	body weighing method		0.0		0					96966	1778
SS/JrTol	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 26 and 66 days) then controlled sodium content diet (2 %) (for 24 days)	Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18.	arterial blood pressure trait	male	64 days-66 days	30		continuous mean	198.0	mmHg	8.0	43.82	tail cuff plethysmography		0.0		0		restrained, 28 degrees C	average of 2-3 readings/day over 4 days		96980	1778
SS/JrTol	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 26 and 66 days) then controlled sodium content diet (2 %) (for 24 days)	Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18.	arterial blood pressure trait	male	64 days-66 days	30		continuous mean	208.0	mmHg	6.0	32.86	tail cuff plethysmography		0.0		0		restrained, 28 degrees C	average of 2-3 readings/day over 4 days		96982	1778
SHRSP/Bbb	systolic blood pressure	controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days)	Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701.	arterial blood pressure trait	not specified	70 days	18	undefined		181.0	mmHg	3.3	14.0	tail cuff plethysmography		0.0		0					97914	1938
SHR-Ndufc2em2Mcwi+/+	systolic blood pressure	controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days)	Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701.	arterial blood pressure trait	not specified	70 days	12	undefined		181.0	mmHg	0.87	3.0	tail cuff plethysmography		0.0		0					97922	1938
SHR-Ndufc2em2Mcwi+/+	systolic blood pressure	controlled protein content diet (19.7 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) and controlled sodium content diet (3.7 mg/g) (for 56 days)	Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701.	arterial blood pressure trait	not specified	98 days	12	undefined		181.0	mmHg	2.6	9.0	tail cuff plethysmography		0.0		0					97923	1938
SHR-Ndufc2em1Mcwi-/+	urine total protein excretion rate	controlled protein content diet (19.7 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) and controlled sodium content diet (3.7 mg/g) (for 84 days)	Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701.	total urine protein amount	not specified	126 days	17			71.0	mg/d	4.61	19.0	urine analysis		0.0		0					97938	1938
SS/JrHsd	plasma estradiol level	controlled sodium content diet (0.1 %) (for 112 days) then bilateral ovariectomy (between 56 and 63 days) and 17 beta-estradiol (5 mg) (between 56 and 63 days)	Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13.	blood estradiol amount	female	112 days	6			21.2	pg/ml	3.2	7.84	radioimmunoassay		0.0	ovx	63	days				102360	2686
SS/NEisSlc	mean arterial blood pressure	controlled sodium content diet (8 %) (for 28 days)	Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18.	arterial blood pressure trait	male	63 days-70 days	8			146.0	mmHg	6.0	16.97	vascular fluid filled catheter		0.0		0					102365	2687
SR/JrHsd	plasma estradiol level	controlled sodium content diet (0.1 %) (for 112 days) then bilateral ovariectomy (between 56 and 63 days) and 17 beta-estradiol (5 mg) (between 56 and 63 days)	Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13.	blood estradiol amount	female	112 days	6			42.9	pg/ml	12.6	30.86	radioimmunoassay		0.0	ovx	63	days				102363	2686
SR/NEisSlc	mean arterial blood pressure	controlled sodium content diet (0.3 %) (for 28 days)	Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18.	arterial blood pressure trait	male	63 days-70 days	7			103.0	mmHg	3.0	7.94	vascular fluid filled catheter		0.0		0					102366	2687
SS/NEisSlc	ratio of change in renal sympathetic nerve activity	controlled sodium content diet (8 %) (for 28 days) then tempol (4 mol/l) (between 0 and 0 hours)	Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18.	kidney sympathetic nerve activity	male	63 days-70 days	8			-18.7	%	2.0	5.66	implanted wire electrode recording method		0.0		0					102373	2687
SR/NEisSlc	heart rate	controlled sodium content diet (8 %) (for 28 days)	Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18.	heart pumping trait	male	63 days-70 days	6			342.0	beats/min	11.0	26.94	vascular fluid filled catheter		0.0		0					102371	2687
SS/NEisSlc	serum urea nitrogen level	controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) then vehicle control condition (for 49 days)	Ishikawa M, et al., Int Heart J. 2013;54(2):98-106.	blood urea nitrogen amount	male	126 days	8			33.6	mg/dl	4.1	11.6	serum urea nitrogen analysis		0.0		0					102329	2684
SS/NEisSlc	both kidneys wet weight to body weight ratio	controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) then tolvaptan (0.05 %) (for 49 days)	Ishikawa M, et al., Int Heart J. 2013;54(2):98-106.	kidney mass	male	126 days	8			4.55	g/kg	0.06	0.17	post excision weight measurement		0.0		0					102324	2684
SS/NEisSlc	creatinine clearance	controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) then vehicle control condition (for 49 days)	Ishikawa M, et al., Int Heart J. 2013;54(2):98-106.	glomerular filtration trait	male	126 days	8			1.9	ml/min	0.5	1.41	serum creatinine analysis		0.0		0					102332	2684
SR/Jr	respiration rate	controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 42 days) then atropine (1 mg/kg) then ambient air (between 0 and 0.4 hours)	Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18.	respiratory function trait	not specified	86 days	5	sampling once per minute		100.0	breaths/min	8.94	20.0	spirometry		0.0		0					103209	2787
SS/Jr	respiration rate	controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 42 days) then atropine (1 mg/kg) then 10% CO2, 20% O2, 70% N2 (10 %) (for 0.4 hours) then ambient air (for 0.1 hours)	Sobajima M, et al., Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2214-20. doi: 10.1152/ajpheart.00615.2010. Epub 2011 Mar 18.	respiratory function trait	not specified	86 days	4	sampling once per minute		96.0	breaths/min	4.0	8.0	spirometry		0.0		0					103212	2787
SR	heart rate	controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 84 days)	Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18.	heart pumping trait	male	126 days	6			375.0	beats/min	11.02	27.0	tail cuff plethysmography		0.0		0					103283	2803
SS-Agtrapem4Mcwi-/-	urine total protein excretion rate	controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 12 days)	Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4.	total urine protein amount	male	60 days-69 days	0			54.0	mg/d	9.0		urine total protein analysis		0.0		0					98435	2059
SS-Agtrapem4Mcwi-/-	heart wet weight	controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 12 days)	Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4.	heart mass	male	60 days-69 days	0			1.08	g	0.03		digital scale post excision weight measurement		0.0		0					98463	2059
SS-Plod1em1Mcwi-/-	body weight	controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 12 days)	Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4.	body mass	male	60 days-69 days	0			298.0	g	6.0		body weighing method		0.0		0					98465	2059
SS-Agtrapem4Mcwi-/-	body weight	controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 12 days)	Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4.	body mass	male	60 days-69 days	0			327.0	g	4.0		body weighing method		0.0		0					98470	2059
SS/Hsd	body weight	controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 12 days)	Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4.	body mass	male	60 days-69 days	0			321.0	g	5.0		body weighing method		0.0		0					98471	2059
SS.BN-(D13Hmgc354-D13Rat32)/Mcwi	diastolic blood pressure	controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days)	Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.	arterial blood pressure trait	male	60 days-67 days	15		serial mean	116.0	mmHg	5.0	19.36	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		intra-carotid radiotelemetry	strain 26-J		98592	2098
SS.BN-(D13Hmgc5885-D13Rat32)/Mcwi	mean arterial blood pressure	controlled sodium content diet (0.4 %) (between 46 and 50.8 days)	Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.	arterial blood pressure trait	male	46 days-53 days	3		serial mean	104.0	mmHg	1.73	3.0	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		intra-carotid radiotelemetry	strain 26-I		98606	2098
SS.BN-(D13Got45-D13Hmgc664)/Mcwi	mean arterial blood pressure	controlled sodium content diet (0.4 %) (between 46 and 50.8 days)	Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.	arterial blood pressure trait	male	46 days-53 days	3		serial mean	103.0	mmHg	2.89	5.0	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		intra-carotid radiotelemetry	strain 26-M		98608	2098
SS/JrHsdMcwi	heart rate	controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days)	Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.	heart pumping trait	male	60 days-67 days	12		serial mean	388.0	beats/min	6.0	20.78	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		intra-carotid radiotelemetry	intra-carotid radiotelemetry		98609	2098
SS.BN-(D13Got42-D13Hmgc664)/Mcwi	heart rate	controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days)	Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.	heart pumping trait	male	60 days-67 days	5		serial mean	385.0	beats/min	6.0	13.42	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		intra-carotid radiotelemetry	intra-carotid radiotelemetry		98617	2098
SS/NEisSlc	serum total protein level	controlled sodium content diet (0.3 %) (for 91 days)	Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806.	blood total protein amount	male	91 days	6			5.33	g/dl	2.35	5.76	serum total protein analysis		0.0		0					100668	2519
SS-Agtrapem4Mcwi-/-	systolic blood pressure	controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days)	Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4.	arterial blood pressure trait	male	58 days-67 days	0		serial mean	139.0	mmHg	2.0		intra-aortic abdominal radiotelemetry		32400.0		0					98416	2059
SS-Agtrapem4Mcwi-/-	heart rate	controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days)	Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4.	heart pumping trait	male	58 days-67 days	0		serial mean	350.0	beats/min	6.0		intra-aortic abdominal radiotelemetry		32400.0		0					98423	2059
SR	heart weight	controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 42 days)	Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18.	heart mass	male	84 days	6			1.0	g	0.04	0.11	post excision weight measurement		0.0		0					103293	2803
SS	heart weight to body weight ratio	controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 84 days)	Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18.	heart mass	male	126 days	6			4.25	g/kg	0.16	0.39	post excision weight measurement		0.0		0					103306	2803
SS	heart left ventricle end-diastolic diameter	controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 84 days)	Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18.	heart left ventricle end-diastolic diameter	male	126 days	6			8.7	mm	0.12	0.3	transthoracic echocardiography		0.0		0					103310	2803
SS	heart left ventricle fractional shortening	controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 42 days)	Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18.	heart left ventricle end-diastolic diameter	male	84 days	7			32.0	%	1.89	5.0	transthoracic echocardiography		0.0		0					103316	2803
SS	plasma insulin level	controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 42 days)	Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18.	blood insulin amount	male	84 days	13			5.0	mU/l	0.55	2.0	plasma insulin analysis		0.0		0					103328	2803
SR	plasma free fatty acids level	controlled sodium content diet (0.3 %) (for 42 days)	Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18.	blood free fatty acid amount	male	42 days	13			1.3	mmol/l	0.08	0.3	thin layer chromatography		0.0		0					103333	2803
SS	plasma free fatty acids level	controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 42 days)	Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18.	blood free fatty acid amount	male	84 days	13			0.9	mmol/l	0.14	0.5	thin layer chromatography		0.0		0					103334	2803
SR	body weight	controlled sodium content diet (6 %) (between 35 and 49 days)	Kamei K, et al., Circ J. 2007 Mar;71(3):390-6.	body mass	male	77 days-91 days	7			360.0	g	9.83	26.0	body weighing method		0.0		0					103345	2804
SS	body weight	controlled sodium content diet (6 %) (between 21 and 28 days)	Kamei K, et al., Circ J. 2007 Mar;71(3):390-6.	body mass	male	63 days-70 days	7			312.0	g	11.72	31.0	body weighing method		0.0		0					103347	2804
SS	systolic blood pressure	controlled sodium content diet (6 %) (between 21 and 28 days)	Kamei K, et al., Circ J. 2007 Mar;71(3):390-6.	arterial blood pressure trait	male	63 days-70 days	7			208.0	mmHg	15.5	41.0	oscillometric sphygmomanometer		0.0		0					103353	2804
SS	systolic blood pressure	controlled sodium content diet (6 %) (between 35 and 49 days)	Kamei K, et al., Circ J. 2007 Mar;71(3):390-6.	arterial blood pressure trait	male	77 days-91 days	7			226.0	mmHg	10.21	27.0	oscillometric sphygmomanometer		0.0		0					103354	2804
SS	systolic blood pressure	controlled sodium content diet (6 %) (between 56 and 70 days)	Kamei K, et al., Circ J. 2007 Mar;71(3):390-6.	arterial blood pressure trait	male	98 days-132 days	7			234.0	mmHg	15.87	42.0	oscillometric sphygmomanometer		0.0		0					103355	2804
SS	heart ventricle septal wall thickness	controlled sodium content diet (6 %) (between 35 and 49 days) then pentobarbital (50 mg/kg)	Kamei K, et al., Circ J. 2007 Mar;71(3):390-6.	heart left ventricle wall thickness	male	77 days-91 days	7			0.16	cm	0.01	0.03	transthoracic echocardiography		0.0		0					103366	2804
SS	heart left ventricle end-diastolic diameter	controlled sodium content diet (6 %) (between 35 and 49 days) then pentobarbital (50 mg/kg)	Kamei K, et al., Circ J. 2007 Mar;71(3):390-6.	heart left ventricle end-diastolic diameter	male	77 days-91 days	7			5.7	mm	0.42	1.1	transthoracic echocardiography		0.0		0					103372	2804
SS	heart left ventricle end-diastolic diameter	controlled sodium content diet (6 %) (between 21 and 28 days) then pentobarbital (50 mg/kg)	Kamei K, et al., Circ J. 2007 Mar;71(3):390-6.	heart left ventricle end-diastolic diameter	male	63 days-70 days	7			6.1	mm	0.42	1.1	transthoracic echocardiography		0.0		0					103371	2804
SR	monophasic action potential	controlled sodium content diet (6 %) (between 21 and 28 days) then pentobarbital (50 mg/kg)	Kamei K, et al., Circ J. 2007 Mar;71(3):390-6.	heart electrical impulse conduction trait	male	63 days-70 days	7			66.0	ms	1.51	4.0	electrocardiography		0.0		0			ecg map		103380	2804
SS	monophasic action potential	controlled sodium content diet (6 %) (between 35 and 49 days) then pentobarbital (50 mg/kg)	Kamei K, et al., Circ J. 2007 Mar;71(3):390-6.	heart electrical impulse conduction trait	male	77 days-91 days	7			98.0	ms	5.29	14.0	electrocardiography		0.0		0			ecg map		103384	2804
SS	conduction velocity	controlled sodium content diet (6 %) (between 35 and 49 days) then pentobarbital (50 mg/kg)	Kamei K, et al., Circ J. 2007 Mar;71(3):390-6.	heart electrical impulse conduction trait	male	77 days-91 days	7			56.0	cm/min	2.65	7.0	electrocardiography		0.0		0			conduction velocity		103390	2804
SS/Hsd	plasma osmolality	controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days)	Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13.	blood molecular composition trait	male	91 days-119 days	6			300.3	umol/g	4.7	11.51	osmometry		0.0		0			p osmolality mosm/kg		102245	2682
SS/Hsd	plasma sodium level	controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days)	Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13.	blood sodium amount	male	91 days-119 days	6			139.6	mmol/l	1.9	4.65	flame atomic emission spectrometry		0.0		0					102243	2682
SR/Hsd	plasma osmolality	controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days)	Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13.	blood molecular composition trait	male	91 days-119 days	6			298.6	umol/g	3.8	9.31	osmometry		0.0		0			p osmolality mosm/kg		102257	2682
SS/Hsd	plasma osmolality	controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then Gnai2 antisense oligonucleotide (4.17 ug/d) (for 21 days) then surgical denervation (for 21 days)	Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13.	blood molecular composition trait	male	91 days-119 days	6			301.8	umol/g	3.6	8.82	osmometry		0.0		0			p osmolality mosm/kg		102262	2682
SS.BN-(D13Hmgc1048-D13Hmgc664)/Mcwi	systolic blood pressure	controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	arterial blood pressure trait	male	58 days-67 days	15		serial mean	153.0	mmHg	4.0	15.49	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		carotid a. to thoracic aorta implant	strain 26-N		98501	2079
SS.BN-(D13Hmgc1048-D13Hmgc664)/Mcwi	heart rate	controlled sodium content diet (0.4 %) (between 23 and 32 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	heart pumping trait	male	44 days-53 days	15		serial mean	401.0	beats/min	4.0	15.49	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		carotid a. to thoracic aorta implant	strain 26-N		98515	2079
SS.BN-(D13Hmgc1041-D13Hmgc885)/Mcwi	systolic blood pressure	controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	arterial blood pressure trait	male	58 days-67 days	15		serial mean	181.0	mmHg	5.0	19.36	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		carotid a. to thoracic aorta implant	strain 26-S		98506	2079
SS.BN-(D13Hmgc1041-D13Hmgc664)/Mcwi	heart rate	controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	heart pumping trait	male	58 days-67 days	13		serial mean	385.0	beats/min	4.0	14.42	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		carotid a. to thoracic aorta implant	strain 26-Q		98525	2079
SS/JrHsdMcwi	mean arterial blood pressure	controlled sodium content diet (0.4 %) (between 50 and 52 days) then controlled sodium content diet (4 %) (for 21 days)	Cowley AW Jr, et al., Hypertension. 2016 Feb;67(2):440-50. doi: 10.1161/HYPERTENSIONAHA.115.06280. Epub 2015 Dec 7.	arterial blood pressure trait	male	71 days-73 days	8		serial mean	151.0	mmHg	3.0	8.49	intra-aortic thoracic radiotelemetry via carotid cannulation		86400.0		0					98643	2118
SS.SHR-(D9Mco113-D9Mco124)/Bj	tibia midshaft endosteal cross-sectional area	controlled sodium content diet (2 %) (between 38 and 42 days)	Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.	tibia morphology trait	male	66 days-70 days	0			2.08	mm2	0.21		micro-computed tomography		0.0		0					98014	1958
SS.BN-(D13Got42-D13Rat130)/Mcwi	urine albumin excretion rate	controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days)	Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.	urine albumin amount	male	60 days-67 days	14			239.0	mg/d	29.0	108.51	urine microalbumin analysis		0.0		0			strain 26-C		98628	2098
SS.BN-(D13Got42-D13Hmgc885)/Mcwi	urine albumin excretion rate	controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days)	Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.	urine albumin amount	male	60 days-67 days	15			172.0	mg/d	25.0	96.82	urine microalbumin analysis		0.0		0			strain 26-F		98631	2098
SS.SHR-(D9Mco115-D9Mco124)/Bj	heart rate	controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)	Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.	heart pumping trait	male	68 days-70 days	6		serial mean	400.0	beats/min	4.24	10.39	radiotelemetry		0.0		0					97977	1958
SS/Jr	systolic blood pressure	controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)	Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.	arterial blood pressure trait	male	68 days-70 days	6		serial mean	203.0	mmHg	4.17	10.21	radiotelemetry		0.0		0					97984	1958
SS.BN-(D13Rat111-D13Rat20)/Mcwi	urine total protein excretion rate	controlled sodium content diet (0.4 %) (for 68 days) then controlled sodium content diet (8 %) (for 21 days)	Moreno C, et al., Am J Physiol Heart Circ Physiol. 2011 Apr;300(4):H1530-5. doi: 10.1152/ajpheart.01026.2010. Epub 2011 Jan 21.	total urine protein amount	male	89 days	12			265.0	mg/d	34.0	117.78	Bradford protein assay		1.0		0			strain 5-10		98698	2138
LH/MavRrrcAek	serum low density lipoprotein cholesterol level	controlled sodium content diet (0.3 %) (for 105 days) then controlled sodium content diet (4 %) (for 21 days)	Ma MCJ, et al., PLoS One. 2017 Aug 8;12(8):e0182650. doi: 10.1371/journal.pone.0182650. eCollection 2017.	blood LDL cholesterol amount	male	126 days	7			33.5	mg/dl	4.4	11.64	serum low-density lipoprotein-cholesterol measurement test		0.0		0					102784	2722
SS/Jr	diastolic blood pressure	controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)	Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.	arterial blood pressure trait	male	68 days-70 days	6		serial mean	149.0	mmHg	3.55	8.7	radiotelemetry		0.0		0					97988	1958
SS.BN-(D13Hmgc64-D13Hmgc23)/Mcwi	mean arterial blood pressure	controlled sodium content diet (0.4 %) (for 70 days) then controlled sodium content diet (8 %) (for 21 days)	Flister MJ, et al., Hypertension. 2013 Apr;61(4):850-6. doi: 10.1161/HYPERTENSIONAHA.111.01008. Epub 2013 Mar 4.	arterial blood pressure trait	male	91 days	13		serial mean	147.0	mmHg	11.0	39.66	intra-aortic abdominal radiotelemetry via femoral cannulation		10800.0		0			strain 9A		98721	2142
SS.BN-(2340-RN34_13048990782)/Mcwi	mean arterial blood pressure	controlled sodium content diet (0.4 %) (for 70 days) then controlled sodium content diet (8 %) (for 21 days)	Flister MJ, et al., Hypertension. 2013 Apr;61(4):850-6. doi: 10.1161/HYPERTENSIONAHA.111.01008. Epub 2013 Mar 4.	arterial blood pressure trait	male	91 days	10		serial mean	190.0	mmHg	4.0	12.65	intra-aortic abdominal radiotelemetry via femoral cannulation		10800.0		0			strain 9D		98724	2142
SS.BN-(2340-RN34_13048990782)/Mcwi	urine albumin excretion rate	controlled sodium content diet (0.4 %) (for 70 days) then controlled sodium content diet (8 %) (for 21 days)	Flister MJ, et al., Hypertension. 2013 Apr;61(4):850-6. doi: 10.1161/HYPERTENSIONAHA.111.01008. Epub 2013 Mar 4.	urine albumin amount	male	91 days	10			320.0	mg/d	29.0	91.71	urine microalbumin analysis		10800.0		0			strain 9D		98730	2142
SS.SHR-(D9Mco113-D9Mco124)/Bj	diastolic blood pressure	controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)	Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.	arterial blood pressure trait	male	68 days-70 days	6		serial mean	126.0	mmHg	2.7	6.61	radiotelemetry		0.0		0					97959	1958
SS/JrHsd	body weight	controlled sodium content diet (0.1 %) (for 112 days) then bilateral ovariectomy (between 56 and 63 days)	Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13.	body mass	female	112 days	6			350.5	g	11.3	27.68	body weighing method		0.0	ovx	63	days				102341	2686
SR/JrHsd	uterus weight	controlled sodium content diet (0.1 %) (for 112 days) then sham surgical control condition (between 56 and 63 days)	Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13.	uterus mass	female	112 days	6			0.41	g	0.02	0.05	post excision weight measurement		0.0	sham ovx	63	days				102355	2686
SS-Renem1Mcwi+/-	body weight	controlled sodium content diet (0.4 %) (for 49 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	body mass	female	70 days	8			203.13	g	3.02	8.54	body weighing method		0.0		0					98293	2038
SS-Renem1Mcwi+/-	single kidney wet weight to body weight ratio	controlled sodium content diet (0.4 %) (for 49 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	kidney mass	male	70 days	9			4.6	g/kg	0.2	0.6	digital scale post excision weight measurement		0.0		0					98302	2038
SS-Clcn6em2Mcwi	mean arterial blood pressure	controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days)	Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4.	arterial blood pressure trait	male	58 days-67 days	0		serial mean	123.0	mmHg	1.0		intra-aortic abdominal radiotelemetry		32400.0		0					98400	2059
SS/Hsd	mean arterial blood pressure	controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days)	Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4.	arterial blood pressure trait	male	58 days-67 days	0		serial mean	136.0	mmHg	2.0		intra-aortic abdominal radiotelemetry		32400.0		0					98403	2059
SS.BN-(D13Hmgc885-D13Hmgc664)/Mcwi	diastolic blood pressure	controlled sodium content diet (0.4 %) (between 23 and 32 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	arterial blood pressure trait	male	44 days-53 days	10		serial mean	86.0	mmHg	2.0	6.32	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		carotid a. to thoracic aorta implant	strain 26-R		98491	2079
SS.BN-(D13Hmgc1041-D13Hmgc885)/Mcwi	mean arterial blood pressure	controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	arterial blood pressure trait	male	58 days-67 days	15		serial mean	168.0	mmHg	4.0	15.49	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		carotid a. to thoracic aorta implant	strain 26-S		98499	2079
SS.BN-(D13Hmgc1041-D13Hmgc664)/Mcwi	diastolic blood pressure	controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	arterial blood pressure trait	male	58 days-67 days	13		serial mean	141.0	mmHg	4.0	14.42	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		carotid a. to thoracic aorta implant	strain 26-Q		98511	2079
SS.BN-(D13Hmgc1048-D13Hmgc1050)/Mcwi	heart rate	controlled sodium content diet (0.4 %) (between 23 and 32 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	heart pumping trait	male	44 days-53 days	11		serial mean	397.0	beats/min	4.0	13.27	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		carotid a. to thoracic aorta implant	strain 26-P		98517	2079
SS/Jr	bone section mineralized tissue surface area	controlled sodium content diet (2 %) (between 38 and 42 days)	Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.	tibia morphology trait	male	66 days-70 days	0			5.3	mm2	0.17		micro-computed tomography		0.0		0					98121	1958
SS.BN-(D13Hmgc1048-D13Hmgc664)/Mcwi	diastolic blood pressure	controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	arterial blood pressure trait	male	58 days-67 days	15		serial mean	117.0	mmHg	4.0	15.49	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		carotid a. to thoracic aorta implant	strain 26-N		98508	2079
SS.BN-(D13Got45-D13Hmgc664)/Mcwi	mean arterial blood pressure	controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days)	Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.	arterial blood pressure trait	male	60 days-67 days	14		serial mean	137.0	mmHg	3.0	11.22	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		intra-carotid radiotelemetry	strain 26-M		98565	2098
SS.BN-(D13Got42-D13Hmgc354)/Mcwi	diastolic blood pressure	controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days)	Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.	arterial blood pressure trait	male	60 days-67 days	16		serial mean	138.0	mmHg	5.0	20.0	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		intra-carotid radiotelemetry	strain 26-D		98585	2098
SS.BN-(D13Rat111-D13Hmgc86)/Mcwi	mean arterial blood pressure	controlled sodium content diet (0.4 %) (for 68 days) then controlled sodium content diet (8 %) (for 21 days)	Moreno C, et al., Am J Physiol Heart Circ Physiol. 2011 Apr;300(4):H1530-5. doi: 10.1152/ajpheart.01026.2010. Epub 2011 Jan 21.	arterial blood pressure trait	male	89 days	14		serial mean	175.0	mmHg	6.0	22.45	intra-aortic abdominal radiotelemetry via femoral cannulation		10800.0		0			strain 5-9		98683	2138
SS-Chr 13BN/Mcwi	urine total protein excretion rate	controlled sodium content diet (0.4 %) (for 68 days) then controlled sodium content diet (8 %) (for 21 days)	Moreno C, et al., Am J Physiol Heart Circ Physiol. 2011 Apr;300(4):H1530-5. doi: 10.1152/ajpheart.01026.2010. Epub 2011 Jan 21.	total urine protein amount	male	89 days	9			162.0	mg/d	24.0	72.0	Bradford protein assay		1.0		0					98686	2138
SS.BN-(D13Rat111-D13Hmgc85)/Mcwi	urine total protein excretion rate	controlled sodium content diet (0.4 %) (for 68 days) then controlled sodium content diet (8 %) (for 21 days)	Moreno C, et al., Am J Physiol Heart Circ Physiol. 2011 Apr;300(4):H1530-5. doi: 10.1152/ajpheart.01026.2010. Epub 2011 Jan 21.	total urine protein amount	male	89 days	21			159.0	mg/d	27.0	123.73	Bradford protein assay		1.0		0			strain 5-11		98692	2138
SS.BN-(D13Rat25-rs106935835)/Mcwi	mean arterial blood pressure	controlled sodium content diet (0.4 %) (for 70 days) then controlled sodium content diet (8 %) (for 21 days)	Hoffman MJ, et al., Hypertension. 2013 Sep;62(3):557-63. doi: 10.1161/HYPERTENSIONAHA.113.01708. Epub 2013 Jul 1.	arterial blood pressure trait	male	91 days	11		serial mean	187.0	mmHg	6.0	19.9	intra-aortic abdominal radiotelemetry via femoral cannulation		10800.0		0			strain 9E		98705	2141
SS.BN-(D13Hmgc64-RN34_13048990782)/Mcwi	urine albumin excretion rate	controlled sodium content diet (0.4 %) (for 70 days) then controlled sodium content diet (8 %) (for 21 days)	Hoffman MJ, et al., Hypertension. 2013 Sep;62(3):557-63. doi: 10.1161/HYPERTENSIONAHA.113.01708. Epub 2013 Jul 1.	urine albumin amount	female	91 days	11			45.0	mg/d	12.0	39.8	urine microalbumin analysis		1.0		0					98712	2141
SS.BN-(D13Rat25-RN34_13048990782)/Mcwi	urine albumin excretion rate	controlled sodium content diet (0.4 %) (for 70 days) then controlled sodium content diet (8 %) (for 21 days)	Hoffman MJ, et al., Hypertension. 2013 Sep;62(3):557-63. doi: 10.1161/HYPERTENSIONAHA.113.01708. Epub 2013 Jul 1.	urine albumin amount	female	91 days	28			70.0	mg/d	8.0	42.33	urine microalbumin analysis		1.0		0			strain 9C		98714	2141
SS.BN-(D13Rat25-rs198199323)/Mcwi	urine albumin excretion rate	controlled sodium content diet (0.4 %) (for 70 days) then controlled sodium content diet (8 %) (for 21 days)	Hoffman MJ, et al., Hypertension. 2013 Sep;62(3):557-63. doi: 10.1161/HYPERTENSIONAHA.113.01708. Epub 2013 Jul 1.	urine albumin amount	female	91 days	9			60.0	mg/d	11.0	33.0	urine microalbumin analysis		1.0		0			strain 9F		98718	2141
SS/NEisSlc	heart left ventricle fractional shortening	controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) then tolvaptan (0.05 %) (for 49 days)	Ishikawa M, et al., Int Heart J. 2013;54(2):98-106.	heart left ventricle end-diastolic diameter	male	126 days	8			44.3	%	1.0	2.83	transthoracic echocardiography		0.0		0					102318	2684
SS/JrHsdMcwi	urine albumin excretion rate	controlled sodium content diet (0.4 %) (between 20 and 29 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	urine albumin amount	male	41 days-50 days	14			2.8	mg/d	0.5	1.87	urine microalbumin analysis		86400.0		0					98528	2079
SS.BN-(D13Hmgc1048-D13Hmgc1045)/Mcwi	urine albumin excretion rate	controlled sodium content diet (0.4 %) (between 20 and 29 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	urine albumin amount	male	41 days-50 days	11			1.2	mg/d	0.3	0.99	urine microalbumin analysis		86400.0		0			strain 26-N		98530	2079
SS.BN-(D13Hmgc1041-D13Hmgc664)/Mcwi	urine albumin excretion rate	controlled sodium content diet (0.4 %) (between 20 and 29 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	urine albumin amount	male	41 days-50 days	13			2.9	mg/d	0.5	1.8	urine microalbumin analysis		86400.0		0			strain 26-Q		98532	2079
SS.BN-(D13Hmgc1041-D13Hmgc885)/Mcwi	urine albumin excretion rate	controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	urine albumin amount	male	59 days-68 days	15			300.0	mg/d	35.0	135.55	urine microalbumin analysis		86400.0		0			strain 26-S		98541	2079
SS-Renem1Mcwi+/-	serum chloride level	controlled sodium content diet (0.4 %) (for 42 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	blood chloride amount	female	63 days	9			99.0	mmol/l	0.54	1.62	automated serum electrolyte analysis		0.0		0					98365	2038
SS-Renem1Mcwi+/-	serum alanine aminotransferase activity level	controlled sodium content diet (0.4 %) (for 42 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	blood alanine transaminase amount	female	63 days	9			31.0	U/l	2.36	7.08	automated serum analysis		0.0		0					98359	2038
SS-Renem1Mcwi-/-	serum bicarbonate level	controlled sodium content diet (0.4 %) (for 42 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	blood bicarbonate amount	male	63 days	8			20.88	mmol/l	0.72	2.04	automated serum bicarbonate test		0.0		0					98369	2038
SS-Renem1Mcwi-/-	serum bicarbonate level	controlled sodium content diet (0.4 %) (for 42 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	blood bicarbonate amount	female	63 days	4			16.75	mmol/l	1.2	2.4	automated serum bicarbonate test		0.0		0					98372	2038
SS-Renem1Mcwi-/-	diastolic blood pressure	controlled sodium content diet (0.4 %) (between 66 and 69 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	arterial blood pressure trait	male	66 days-69 days	8		serial mean	46.44	mmHg	2.34	6.62	intra-aortic abdominal radiotelemetry		32400.0		0					98381	2038
SS.BN-(D13Got42-D13Hmgc885)/Mcwi	systolic blood pressure	controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days)	Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.	arterial blood pressure trait	male	60 days-67 days	15		serial mean	171.0	mmHg	5.0	19.36	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		intra-carotid radiotelemetry	strain 26-F		98573	2098
SS.BN-(D13Got42-D13Hmgc885)/Mcwi	mean arterial blood pressure	controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days)	Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.	arterial blood pressure trait	male	60 days-67 days	15		serial mean	151.0	mmHg	5.0	19.36	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		intra-carotid radiotelemetry	strain 26-F		98558	2098
SS.BN-(D13Hmgc5885-D13Rat32)/Mcwi	mean arterial blood pressure	controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days)	Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.	arterial blood pressure trait	male	60 days-67 days	14		serial mean	170.0	mmHg	5.0	18.71	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		intra-carotid radiotelemetry	strain 26-I		98561	2098
SS-Nppbem2Mcwi-/-	heart left ventricle end-diastolic posterior wall thickness	controlled sodium content diet (for 21 days)	Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11.	heart left ventricle posterior wall thickness	male	98 days	4			1.87	mm	0.2	0.4	echocardiography		0.0		0					99715	2319
SS-Nppbem2Mcwi+/+	heart left ventricle end-systolic posterior wall thickness	controlled sodium content diet (for 21 days)	Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11.	heart left ventricle posterior wall thickness	male	98 days	4			2.51	mm	0.23	0.46	echocardiography		0.0		0					99720	2319
SS.BN-(D13Rat130-D13Rat32)/Mcwi	mean arterial blood pressure	controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days)	Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.	arterial blood pressure trait	male	60 days-67 days	12		serial mean	141.0	mmHg	3.0	10.39	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		intra-carotid radiotelemetry	strain 26-K		98563	2098
SS.BN-(D13Rat151-D13Rat197)/Mcwi	systolic blood pressure	controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days)	Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.	arterial blood pressure trait	male	60 days-67 days	14		serial mean	156.0	mmHg	5.0	18.71	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		intra-carotid radiotelemetry			98567	2098
SS/Jr	bone section mineralized tissue volume	controlled sodium content diet (2 %) (between 38 and 42 days)	Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.	tibia morphology trait	male	66 days-70 days	0			4.92	mm3	0.88		micro-computed tomography		0.0		0			bone volume		98019	1958
SR/JrIpcv	systolic blood pressure	controlled sodium content diet (0.3 %)	Hojn¿ S, et al., Physiol Res. 2005;54(2):201-6.	arterial blood pressure trait	male	0 days	0	undefined		137.0	mmHg	3.0		vascular indwelling catheter method		0.0		0					102395	2688
SS/JrIpcv	plasma triglyceride level	controlled sodium content diet (0.3 %)	Hojn¿ S, et al., Physiol Res. 2005;54(2):201-6.	blood triglyceride amount	male	0 days	0			1.2	mmol/l	0.16		plasma triglyceride analysis		0.0		0					102402	2688
SS.BN-(D13Hmgc1048-D13Hmgc1045)/Mcwi	urine albumin excretion rate	controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	urine albumin amount	male	59 days-68 days	11			117.0	mg/d	36.0	119.4	urine microalbumin analysis		86400.0		0			strain 26-O		98537	2079
SS-Nppbem2Mcwi-/-	urine creatinine excretion rate	controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 12 days)	Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4.	urine creatinine amount	male	60 days-69 days	0			11.5	mg/d	0.5		urine creatinine analysis		0.0		0					98438	2059
SS-Plod1em1Mcwi-/-	urine creatinine excretion rate	controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 12 days)	Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4.	urine creatinine amount	male	60 days-69 days	0			9.0	mg/d	0.4		urine creatinine analysis		0.0		0					98437	2059
SS-Mthfrem1Mcwi-/+	urine creatinine excretion rate	controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 12 days)	Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4.	urine creatinine amount	male	60 days-69 days	0			12.1	mg/d	0.4		urine creatinine analysis		0.0		0					98441	2059
SS.SHR-(D9Mco115-D9Mco124)/Bj	mean arterial blood pressure	controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)	Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.	arterial blood pressure trait	male	68 days-70 days	6		serial mean	172.0	mmHg	11.48	28.12	radiotelemetry		0.0		0					97966	1958
WKY/NHsd	skin chloride level to skin dry weight ratio	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)	Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.	skin chloride amount	male	0 days	7			0.07	mmol/g	0.01	0.02	ex vivo analysis of atomic composition following dry ashing		0.0		0		ashed skin	skin cl mmol/g		99137	2238
WKY/NHsd	plasma cystatin C level	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)	Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.	blood cystatin C amount	male	0 days	7			3.5	mg/l	0.2	0.53	automated plasma protein analysis		0.0		0					99177	2238
SS.SHR-(D9Mco110-D9Mco124)/Bj	systolic blood pressure	controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)	Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.	arterial blood pressure trait	male	68 days-70 days	7		serial mean	157.0	mmHg	0.82	2.17	radiotelemetry		0.0		0					97951	1958
SS.BN-(D13Rat130-D13Rat32)/Mcwi	systolic blood pressure	controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days)	Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.	arterial blood pressure trait	male	60 days-67 days	12		serial mean	159.0	mmHg	4.0	13.86	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		intra-carotid radiotelemetry	strain 26-K		98578	2098
WKY/NHsd	urine sodium excretion rate	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)	Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.	urine sodium amount	male	0 days	7			41.9	mEq/d	5.2	13.76	urine sodium analysis		0.0		0					99185	2238
SR/NEisSlc	urine aldosterone excretion rate	controlled sodium content diet (0.3 %) (for 84 days)	Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806.	urine aldosterone amount	male	84 days	6			39.87	ng/d	11.4	27.92	radioimmunoassay		0.0		0			ng/d		100695	2519
SR/NEisSlc	kidney weight	controlled sodium content diet (0.3 %) (for 91 days)	Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806.	kidney mass	male	91 days	6			1.43	g	0.04	0.09	post excision weight measurement		0.0		0					100703	2519
SS-Renem1Mcwi+/-	retroperitoneal fat pad weight to body weight ratio	controlled sodium content diet (0.4 %) (for 49 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	retroperitoneal fat pad mass	male	70 days	9			0.49	%	0.05	0.15	digital scale post excision weight measurement		0.0		0					98308	2038
SS-Renem1Mcwi+/+	single kidney wet weight to body weight ratio	controlled sodium content diet (0.4 %) (for 49 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	kidney mass	female	70 days	8			5.1	g/kg	0.2	0.57	digital scale post excision weight measurement		0.0		0					98304	2038
SS-Renem1Mcwi+/+	retroperitoneal fat pad weight to body weight ratio	controlled sodium content diet (0.4 %) (for 49 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	retroperitoneal fat pad mass	male	70 days	5			0.44	%	0.07	0.16	digital scale post excision weight measurement		0.0		0					98307	2038
SS-Renem1Mcwi+/-	urine total protein excretion rate	controlled sodium content diet (0.4 %) (for 35 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	total urine protein amount	male	56 days	9			85.47	mg/d	10.93	32.79	urine total protein analysis		0.0		0					98320	2038
SS-Renem1Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (0.4 %) (for 35 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	urine sodium amount	male	56 days	5			0.65	mEq/d	0.25	0.56	urine sodium analysis		0.0		0					98325	2038
SS-Renem1Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (0.4 %) (for 35 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	urine sodium amount	female	56 days	8			0.71	mEq/d	0.08	0.23	urine sodium analysis		0.0		0					98328	2038
SS-Renem1Mcwi+/-	urine creatinine excretion rate	controlled sodium content diet (0.4 %) (for 35 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	urine creatinine amount	male	56 days	9			8.41	mg/d	0.4	1.2	urine creatinine analysis		0.0		0					98332	2038
SS-Renem1Mcwi+/-	serum urea nitrogen level	controlled sodium content diet (0.4 %) (for 42 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	blood urea nitrogen amount	male	63 days	8			112.25	mg/dl	7.52	21.27	serum urea nitrogen analysis		0.0		0					98339	2038
SS-Renem1Mcwi+/-	serum creatinine level	controlled sodium content diet (0.4 %) (for 42 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	blood creatinine amount	female	63 days	9			0.26	mg/dl	0.02	0.06	serum creatinine analysis		0.0		0					98347	2038
WKY/NHsd	creatinine clearance	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)	Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.	glomerular filtration trait	male	0 days	7			3.5	ml/min	0.3	0.79	urine creatinine analysis		0.0		0					99181	2238
SS.SHR-(D9Mco113-D9Mco124)/Bj	heart rate	controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)	Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.	heart pumping trait	male	68 days-70 days	6		serial mean	390.0	beats/min	4.83	11.83	radiotelemetry		0.0		0					97975	1958
F344-Hsd11b2em1Jmul+/+	mean arterial blood pressure	controlled sodium content diet (0.3 %)	Mullins LJ, et al., Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15.	arterial blood pressure trait	not specified	182 days-210 days	4	1000hz 5min/hour		113.5	mmHg			intra-aortic abdominal radiotelemetry via femoral cannulation		0.0		0					104994	3008
F344-Hsd11b2em1Jmul+/+	food intake rate	controlled sodium content diet (0.3 %)	Mullins LJ, et al., Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15.	eating behavior trait	male	161 days	4			15.13	g/d	0.25	0.5	food intake measuring method		0.0		0					104997	3008
F344-Hsd11b2em1Jmul+/+	food intake rate	controlled sodium content diet (0.3 %) then controlled sodium content diet (0.03 %) (between 7 and 10 days)	Mullins LJ, et al., Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15.	eating behavior trait	male	168 days	5			13.6	g/d	0.3	0.67	food intake measuring method		0.0		0					105001	3008
F344-Hsd11b2em1Jmul-/-	water drink intake rate	controlled sodium content diet (0.3 %) then controlled sodium content diet (3 %) (between 7 and 10 days)	Mullins LJ, et al., Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15.	drinking behavior trait	male	168 days	5			76.38	ml/d	1.92	4.29	drink intake measuring method		0.0		0					105006	3008
F344-Hsd11b2em1Jmul-/-	water drink intake rate	controlled sodium content diet (0.3 %) then controlled sodium content diet (0.03 %) (between 7 and 10 days)	Mullins LJ, et al., Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15.	drinking behavior trait	male	168 days	5			13.1	ml/d	0.6	1.34	drink intake measuring method		0.0		0					105008	3008
F344-Hsd11b2em1Jmul-/-	timed urine volume	controlled sodium content diet (0.3 %)	Mullins LJ, et al., Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15.	urine output	male	161 days	5			16.15	ml/d	0.78	1.74	urine volume measurement method		0.0		0					105010	3008
F344-Hsd11b2em1Jmul+/+	timed urine volume	controlled sodium content diet (0.3 %) then controlled sodium content diet (0.03 %) (between 7 and 10 days)	Mullins LJ, et al., Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15.	urine output	male	168 days	5			3.4	ml/d	0.2	0.45	urine volume measurement method		0.0		0					105013	3008
F344-Hsd11b2em1Jmul-/-	timed urine volume	controlled sodium content diet (0.3 %) then controlled sodium content diet (3 %) (between 7 and 10 days)	Mullins LJ, et al., Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15.	urine output	male	168 days	5			69.15	ml/d	2.06	4.61	urine volume measurement method		0.0		0					105012	3008
F344-Hsd11b2em1Jmul+/+	urine sodium level	controlled sodium content diet (0.3 %) then controlled sodium content diet (0.03 %) (between 7 and 10 days)	Mullins LJ, et al., Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15.	urine sodium amount	male	168 days	5			35.1	mmol/l	9.1	20.35	urine sodium analysis		0.0		0					105025	3008
F344-Hsd11b2em1Jmul+/+	urine sodium level	controlled sodium content diet (0.3 %)	Mullins LJ, et al., Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15.	urine sodium amount	male	161 days	4			817.2	mmol/l	39.6	79.2	urine sodium analysis		0.0		0					105021	3008
F344-Hsd11b2em1Jmul-/-	urine potassium level	controlled sodium content diet (0.3 %) then controlled sodium content diet (3 %) (between 7 and 10 days)	Mullins LJ, et al., Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15.	urine potassium amount	male	168 days	5			1862.4	mmol/l	334.5	747.96	urine potassium analysis		0.0		0					105030	3008
F344-Hsd11b2em1Jmul+/+	urine potassium level	controlled sodium content diet (0.3 %) then controlled sodium content diet (0.03 %) (between 7 and 10 days)	Mullins LJ, et al., Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15.	urine potassium amount	male	168 days	5			1151.0	mmol/l	44.5	99.51	urine potassium analysis		0.0		0					105031	3008
SS-Plekha7em4Mcwi+/+	urine sodium level	controlled sodium content diet (8 %) (for 28 days)	Endres BT, et al., Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12817-22. doi: 10.1073/pnas.1410745111. Epub 2014 Aug 18.	urine sodium amount	male	91 days	10			284.0	mmol/l	16.0	50.6	urine sodium analysis		0.0		0					105782	3022
SS-Plekha7em4Mcwi-/-	timed urine volume	controlled sodium content diet (0.4 %) (for 63 days)	Endres BT, et al., Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12817-22. doi: 10.1073/pnas.1410745111. Epub 2014 Aug 18.	urine output	male	63 days	10			5.26	ml/d	0.51	1.61	urine volume measurement method		0.0		0					105765	3022
SS-Plekha7em4Mcwi-/-	timed urine volume	controlled sodium content diet (8 %) (for 21 days)	Endres BT, et al., Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12817-22. doi: 10.1073/pnas.1410745111. Epub 2014 Aug 18.	urine output	male	84 days	10			71.34	ml/d	2.26	7.15	urine volume measurement method		0.0		0					105771	3022
SS-Plekha7em4Mcwi-/-	urine sodium level	controlled sodium content diet (8 %) (for 14 days)	Endres BT, et al., Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12817-22. doi: 10.1073/pnas.1410745111. Epub 2014 Aug 18.	urine sodium amount	male	77 days	10			348.0	mmol/l	16.0	50.6	urine sodium analysis		0.0		0					105779	3022
SS-Plekha7em4Mcwi+/+	urine potassium level	controlled sodium content diet (8 %) (for 28 days)	Endres BT, et al., Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12817-22. doi: 10.1073/pnas.1410745111. Epub 2014 Aug 18.	urine potassium amount	male	91 days	10			15.1	mmol/l	1.2	3.79	urine potassium analysis		0.0		0					105792	3022
SS-Plekha7em4Mcwi+/+	body weight	controlled sodium content diet (0.4 %) (for 42 days)	Endres BT, et al., Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12817-22. doi: 10.1073/pnas.1410745111. Epub 2014 Aug 18.	body mass	male	63 days	10			250.0	g	8.0	25.3	body weighing method		0.0		0					105736	3022
SS-Plekha7em4Mcwi-/-	urine total protein excretion rate	controlled sodium content diet (8 %) (for 28 days)	Endres BT, et al., Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12817-22. doi: 10.1073/pnas.1410745111. Epub 2014 Aug 18.	total urine protein amount	male	91 days	10			190.0	mg/d	16.0	50.6	urine protein analysis		0.0		0					105741	3022
SHRSP/A3NCrl	brain infarction volume	controlled protein content diet (16 %) (between 28 and 120 days) and controlled sodium content diet (4 %) (for 28 days) and controlled potassium content diet (0.75 %) (for 28 days) and unilateral carotid artery occlusion (for 28 days)	Yang Y, etal., Neurobiol Dis. 2018 Jun;114:95-110. doi: 10.1016/j.nbd.2018.02.012. Epub 2018 Feb 24.	brain integrity trait	male	112 days	8			19.7	mm3	4.4	12.45	magnetic resonance imaging	corpus callosum	0.0		0		corpus callosum-right hemisphere	corpus callosum-right hemisphere		107282	3079
SS-Chr 2BN/Mcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	male	80 days-99 days	10			174.3	mg/d	23.06	72.93	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52728	482
SS-Chr 4BN/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	female	80 days-99 days	8			11.82	mEq/d	1.51	4.27	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52772	482
LEW/Crl	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	9			-2.43	beats/min	15.64	46.93	vascular fluid filled catheter				0					50517	481
FHH-Chr 12BN/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	female	80 days-99 days	10			12.16	mEq/d	2.29	7.24	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52780	482
SS-Chr 18BN/Mcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	renin activity	male	87 days-120 days	5			0.3	ng/ml/h	0.03	0.07	radioimmunoassay				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50535	481
WKY/NCrl	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	9			118.22	mmHg	2.65	7.94	vascular fluid filled catheter				0					50546	481
BN/NHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	9			0.28	beats/min	13.27	39.81	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	50624	481
SS-Chr 18BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	8			139.27	mmHg	3.66	10.35	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	50638	481
SS-Chr 9BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	6			46.25	mmHg	3.11	7.61	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50660	481
FHH/EurMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	6			55.32	mmHg	2.61	6.39	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50663	481
SS-Chr 16BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	5			125.38	mmHg	2.94	6.57	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50677	481
LEW/Crl	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	blood creatinine amount	female	87 days-120 days	6			0.33	mg/dl	0.01	0.03	radioimmunoassay				0					50691	481
SS-Chr 9BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	14			6.91	mmHg	2.02	7.55	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50699	481
BN/NHsdMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	4			-9.46	mmHg	3.26	6.51	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50813	481
Crl:CD(SD)	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	4			-0.2	mmHg	2.08	4.16	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	50816	481
F344/DuCrl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	1			-0.7	mmHg			vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	50819	481
LEW/Crl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	9			-0.68	mmHg	4.11	12.32	vascular fluid filled catheter				0					50830	481
SS/JrHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	5			8.29	beats/min	21.22	47.46	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50905	481
SS-Chr 16BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	5			34.4	mmHg	3.93	8.78	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50902	481
SS-Chr 9BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	6			128.48	mmHg	4.68	11.46	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50946	481
GH/OmrMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	9			18.73	mmHg	1.8	5.4	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50963	481
SHR/NCrl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	4			29.71	mmHg	9.04	18.07	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50966	481
Hsd:SD	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	14			13.28	mmHg	2.14	8.01	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	50958	481
SHR/NCrl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	8			1.24	mmHg	2.67	7.55	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51028	481
SS-Chr 9BN/Mcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	glomerular filtration trait	female	87 days-120 days	12			0.56	ml/min	0.15	0.53	urine creatinine analysis				0				Moms and pups used in studies were fed Teklad	51059	481
FHH/EurMcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	glomerular filtration trait	male	87 days-120 days	4			1.21	ml/min	0.21	0.42	urine creatinine analysis				0				Moms and pups used in studies were fed Teklad	51062	481
SS/Jr	plasma chloride level	controlled sodium content diet (8 %) (between 8 and 10 days)	Huang BS, et al., Hypertension. 2007 Apr 9;.	blood chloride amount	male	43 days-52 days	12			105.0	mmol/l	2.0	6.93	chloride ion-selective electrode method				0		chloride ion-selective electrode			13330	344
Crl:CD(SD)	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	7			113.23	mmHg	1.95	5.15	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51076	481
GH/OmrMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	3			-11.72	beats/min	10.1	17.5	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51090	481
SS-Chr 16BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	5			3.87	mmHg	2.0	4.48	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51102	481
FHH/EurMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	5			-27.08	beats/min	15.11	33.78	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51217	481
GH/OmrMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	9			-12.27	beats/min	14.94	44.83	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51220	481
FHH/EurMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	2			4.3	beats/min	93.3	131.95	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51234	481
F344/DuCrl	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	glomerular filtration trait	female	87 days-120 days	8			0.92	ml/min	0.08	0.22	urine creatinine analysis				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51259	481
BN/NHsdMcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	1			432.84	beats/min			vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51254	481
FHH/EurMcwi	urine sodium excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	urine sodium amount	female	87 days-120 days	8			1.74	mEq/d	0.27	0.76	flame atomic emission spectrometry				0				Moms and pups used in studies were fed Dyets	51265	481
SHR/NCrl	urine sodium excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	urine sodium amount	male	87 days-120 days	10			1.46	mEq/d	0.11	0.36	flame atomic emission spectrometry				0				Moms and pups used in studies were fed Dyets	51270	481
SS-Chr 9BN/Mcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	15			420.94	beats/min	4.88	18.88	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51287	481
FHH/EurMcwi	urine sodium excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	urine sodium amount	male	87 days-120 days	6			5.93	mEq/d	0.44	1.07	flame atomic emission spectrometry				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51299	481
SS/Jr	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	arterial blood pressure trait	not specified	65 days-70 days	0			197.0	mmHg	3.85		tail cuff plethysmography		0.0		0					67513	749
SS.SHR-(D9Mco72-D9Uia4)/Mco	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	arterial blood pressure trait	not specified	65 days-70 days	0			181.0	mmHg	3.91		tail cuff plethysmography		0.0		0					67516	749
SS.SHR-(D9Rat7-D9Rat52)/Mco	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	arterial blood pressure trait	not specified	65 days-70 days	0			203.0	mmHg	6.11		tail cuff plethysmography		0.0		0					67526	749
SS.SHR-(D9Mco72-D9Rat55)/Mco	body weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	body mass	not specified	0 days	0			302.0	g	2.88		body weighing method		0.0		0					67528	749
SS.SHR-(D9Mco72-D9Mco109)/Mco	heart wet weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	heart mass	not specified	0 days	0			1.23	g	0.01		post excision weight measurement		0.0		0					67549	749
SS.SHR-(D9Mco72-D9Mco109)/Mco	heart weight to body weight ratio	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	heart mass	not specified	0 days	0			4.01	g/kg	0.03		post excision weight measurement		0.0		0					67565	749
SS.SHR-(D9Rat7-D9Rat84)/Mco	heart weight to body weight ratio	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	heart mass	not specified	0 days	0			4.09	g/kg	0.07		post excision weight measurement		0.0		0					67573	749
SS/Jr	heart weight to body weight ratio	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	heart mass	not specified	0 days	0			4.24	g/kg	0.1		post excision weight measurement		0.0		0					67575	749
Hsd:SD	urine sodium excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	urine sodium amount	female	87 days-120 days	16			0.74	mEq/d	0.11	0.43	flame atomic emission spectrometry				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	51399	481
SS-Chr 16BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	2			-109.6	beats/min	11.6	16.4	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51407	481
SS/JrHsdMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	17			30.86	mmHg	2.26	9.32	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51421	481
FHH/EurMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	8			38.72	mmHg	3.96	11.19	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51430	481
SS/JrHsdMcwi	urine total protein excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	total urine protein amount	female	87 days-120 days	11			41.53	mg/d	8.23	27.31	automated urine analysis				0				Moms and pups used in studies were fed Dyets	51441	481
SS-Chr 18BN/Mcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	glomerular filtration trait	male	87 days-120 days	4			1.66	ml/min	0.1	0.2	urine creatinine analysis				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51447	481
SS-Chr 16BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	urine albumin amount	male	87 days-120 days	8			3.91	mg/d	0.77	2.17	automated urine analysis				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51459	481
SHR/NCrl	urine sodium excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	urine sodium amount	male	87 days-120 days	8			1.08	mEq/d	0.16	0.45	flame atomic emission spectrometry				0				Moms and pups used in studies were fed Teklad	51521	481
SS-Chr 16BN/Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	blood creatinine amount	male	87 days-120 days	6			0.3	mg/dl	0.06	0.15	radioimmunoassay				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51538	481
SS-Chr 16BN/Mcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	glomerular filtration trait	male	87 days-120 days	7			1.93	ml/min	0.1	0.27	urine creatinine analysis				0				Moms and pups used in studies were fed Dyets	51546	481
SS-Chr 16BN/Mcwi	urine total protein excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	total urine protein amount	female	87 days-120 days	6			19.21	mg/d	2.42	5.92	automated urine analysis				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51555	481
FHH/EurMcwi	urine albumin excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	urine albumin amount	female	87 days-120 days	8			1.96	mg/d	0.27	0.76	automated urine analysis				0				Moms and pups used in studies were fed Dyets	51560	481
SHR/NCrl	urine albumin excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	urine albumin amount	male	87 days-120 days	10			1.03	mg/d	0.16	0.51	automated urine analysis				0				Moms and pups used in studies were fed Dyets	51566	481
SHR/NCrl	urine albumin excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	urine albumin amount	female	87 days-120 days	9			0.29	mg/d	0.05	0.16	automated urine analysis				0				Moms and pups used in studies were fed Dyets	51569	481
BN/NHsdMcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	8			437.8	beats/min	17.4	49.21	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51588	481
Crl:CD(SD)	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	renin activity	male	87 days-120 days	6			1.14	ng/ml/h	0.3	0.74	radioimmunoassay				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	51603	481
SS/JrHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	3			-12.6	beats/min	13.02	22.55	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51608	481
SS.LEW-(D3Mco21-D3Rat17)/Ayd	mean arterial blood pressure	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	arterial blood pressure trait	male	68 days-98 days	4			166.0	mmHg	9.0	18.0	radiotelemetry		30		0					11941	226
SS/JrHsdMcwi	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	18			157.55	mmHg	5.0	21.21	vascular fluid filled catheter				0				Moms and pups used in studies were fed Dyets	51628	481
SS.LEW-(D10Chm128-D10Chm169)/Ayd	mean arterial blood pressure	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	arterial blood pressure trait	male	68 days-98 days	8			184.0	mmHg	8.0	22.63	radiotelemetry		30		0					11957	226
SS-Chr 16BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	5			-20.24	beats/min	14.12	31.57	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50337	481
Crl:CD(SD)	mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	7			109.1	mmHg	3.86	10.21	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	50351	481
Hsd:SD	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	7			3.42	mmHg	1.85	4.89	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	50342	481
SS-Chr 20BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	1			8.0	beats/min			vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	50354	481
SS-Chr 16BN/Mcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	renin activity	male	87 days-120 days	8			3.34	ng/ml/h	0.14	0.39	radioimmunoassay				0				Moms and pups used in studies were fed Dyets	50393	481
F344/DuCrl	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	renin activity	male	87 days-120 days	7			15.17	ng/ml/h	1.06	2.81	radioimmunoassay				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	50414	481
SS-Chr 16BN/Mcwi	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	2			455.2	beats/min	31.4	44.41	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	50447	481
SS.LEW-(D18Chm91-D18Rat67)/Ayd	both kidneys wet weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	kidney mass	male	98 days	5			10.0	g/kg	0.4	0.89	post excision weight measurement		0		0					64774	226
SS.LEW-(D17Chm14-D17Rat181)/Ayd	both kidneys wet weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	kidney mass	male	98 days	5			9.7	g/kg	0.2	0.45	post excision weight measurement		0		0					64779	226
SS-Chr 16BN/Mcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	renin activity	female	87 days-120 days	6			2.08	ng/ml/h	0.23	0.56	radioimmunoassay				0				Moms and pups used in studies were fed Dyets	50458	481
SS.LEW-(D17Chm9-D17Rat97)/Ayd	both kidneys wet weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	kidney mass	male	98 days	10			10.3	g/kg	0.4	1.26	post excision weight measurement		0		0					64777	226
SS-Chr 16BN/Mcwi	plasma renin activity level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	renin activity	male	87 days-120 days	8			1.22	ng/ml/h	0.11	0.31	radioimmunoassay				0				Moms and pups used in studies were fed Dyets	50461	481
SS.LEW-(D10Rat27-Igfbp4)/Ayd	both kidneys wet weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	kidney mass	male	98 days	7			10.9	g/kg	0.4	1.06	post excision weight measurement		0		0					64787	226
SS.LEW-(D3Rat52-D3Rat130)/Ayd	both kidneys wet weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	kidney mass	male	98 days	7			9.5	g/kg	0.2	0.53	post excision weight measurement		0		0					64793	226
SS.MNS-(D2Wox27-Adh1)/Ayd	heart left ventricle weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	heart left ventricle mass	male	98 days	5			3.1	mg/g	0.1	0.22	post excision weight measurement		0		0					64956	226
SS.LEW-(D10Mco84-D10Rat58)/Mco	heart weight to body weight ratio	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Saad Y, et al., Hypertension. 2007	heart mass	male	64 days-66 days	0			4.67	g/kg	0.09		post excision weight measurement				0					12054	205
SS.LEW-(D3Rat52-D3Rat130)/Ayd	heart weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	heart mass	male	98 days	7			3.23	g/kg	0.09	0.24	post excision weight measurement		0		0					12097	226
SS.LEW-(D16Rat38-D16Chm66)/Ayd	heart weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	heart mass	male	98 days	8			3.9	g/kg	0.1	0.28	post excision weight measurement		0		0					12114	226
SS/Jr	body weight	controlled sodium content diet (2 %) (for 24 days)	Saad Y, et al., Mamm Genome. 2008 Jan 4	body mass	male	64 days-68 days	20			306.0	g	3.09	13.82	body weighing method		0		0					12144	232
SS/Jr	heart wet weight	controlled sodium content diet (2 %) (for 24 days)	Saad Y, et al., Mamm Genome. 2008 Jan 4	heart mass	male	64 days-68 days	20			1.18	g	0.01	0.04	post excision weight measurement		0		0					12155	232
SS.MNS-(D10Mco62-D10Got99)/Mco	heart wet weight	controlled sodium content diet (2 %) (for 24 days)	Saad Y, et al., Mamm Genome. 2008 Jan 4	heart mass	male	64 days-68 days	20			1.24	g	0.01	0.04	post excision weight measurement		0		0					12204	232
SS/Jr	heart wet weight	controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)	Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.	heart mass	male	70 days-72 days	40			1.13	g	0.01	0.06	post excision weight measurement				0					12254	237
SS/Jr	heart wet weight	controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)	Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.	heart mass	male	70 days-72 days	20			1.27	g	0.02	0.07	post excision weight measurement				0					12262	237
SS.SR-(D3Mco36-D3Got159)/Jr	heart wet weight	controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)	Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.	heart mass	male	70 days-72 days	20			1.15	g	0.01	0.05	post excision weight measurement				0					12259	237
SS.SHR-(D8Uia1-D8Rat90)/Mco	both kidneys wet weight	controlled sodium content diet (0.3 %)	Packard M, et al., Am J Physiol Renal Physiol. 2009 Apr;296(4):F839-46. Epub 2009 Jan 28.	kidney mass	male	84 days	12			2.7	g	0.02	0.08	post excision weight measurement		0		0					12339	246
SS.SHR-(D9Wox16-D9Rat64)/Mco	heart rate	controlled sodium content diet (2 %) (for 37 days)	Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.	heart pumping trait	male	75 days-79 days	5			396.0	beats/min	8.72	19.5	intra-aortic abdominal radiotelemetry		172800		0					64987	305
SS.SHR-(D9Mco72-D9Mco93)/Mco	urine total protein excretion rate	controlled sodium content diet (2 %) (between 31 and 32 days)	Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.	total urine protein amount	male	71 days-73 days	20			61.64	mg/d	4.56	20.39	pyrogallol red-molybdate complex-based urine total protein analysis		86400		0					64990	305
SS.LEW-(D10Got112-Igfbp4)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 23 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	arterial blood pressure trait	male	56 days-60 days	5			151.0	mmHg	2.24	5.0	radiotelemetry		86400		0			two 24 hours widely separated periods, data represent averages of all readings over the 24-h measurements		65001	542
SS.LEW-(D18Rat29-D18Rat55)/Ayd	body weight	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	body mass	male	77 days	11			324.5	g	3.89	12.9	body weighing method		0		0					65006	542
SS.BN-(D13Rat127-D13Rat61)/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (for 18 days)	Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12.	urine albumin amount	male	84 days-88 days	12			70.8	mg/d	12.2	42.26	urine analysis		86400		0					65229	15
SS.BN-(D13Rat101-D13Rat46)/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (for 18 days)	Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12.	urine albumin amount	male	84 days-88 days	12			51.5	mg/d	7.9	27.37	urine analysis		86400		0					65234	15
SS.BN-(D13Rat151-D13Rat197)/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (for 18 days)	Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12.	urine albumin amount	female	84 days-88 days	12			17.8	mg/d	2.1	7.27	urine analysis		86400		0					65248	15
SS.LEW-(D10Got112-Igfbp4)/Ayd	heart left ventricle wet weight	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	heart left ventricle mass	male	77 days	5			0.8	g	0.05	0.12	post excision weight measurement		0		0					65033	542
SS.BN-(D13Rat7-D13Rat88)/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 16 and 19 days)	Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12.	arterial blood pressure trait	female	86 days-89 days	12			165.0	mmHg	4.2	14.55	vascular fluid filled catheter	left femoral artery	14400		0		on 3 consecutive days			65161	15
FHH-Chr 1BN-Sorcs1em1Mcwi-/-	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	12			7.01	mg/d	0.5	1.73	automated urine analysis				0				-	66709	717
SS-Tfdp2em2Mcwi-/-	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	3			9.51	mg/d	0.73	1.26	automated urine analysis				0				-	66736	717
SS-Nckap5em3Mcwi+/+	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	2			11.28	mg/d	1.27	1.8	automated urine analysis				0				-	66744	717
SS-Gpr183em3Mcwi-/-	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	8			1.57	g	0.07	0.21	post excision weight measurement				0				-	66805	717
SS-Ube2q2em3Mcwi-/-	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	2			1.4	g	0.0	0.0	post excision weight measurement				0				-	66811	717
SR/Jr	body weight	controlled sodium content diet (0.2 %) (for 168 days)	Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23	body mass	male	203 days	10			422.0	g	5.4	17.08	body weighing method		0		0				4 rats per cage, 2 SR/Jr 2 LEW/NCrl	64709	222
SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi-/-	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	4			10.68	mEq/d	0.94	1.88	automated urine analysis				0				-	66854	717
SS-Cybaem1Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	2			8.17	mEq/d	4.75	6.71	automated urine analysis				0				-	66860	717
SS-Chr 5BN-Cyp4a2em1Mcwi-/-	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	7			7.84	mEq/d	1.38	3.66	automated urine analysis				0				-	66865	717
SS-Ncf2em1Mcwi-/-	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	6			37.83	mg/d	10.61	25.99	automated urine analysis				0				-	66873	717
SS-Acad10em2Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	5			8.32	mEq/d	1.39	3.11	automated urine analysis				0				-	66870	717
SS-Ncf2em1Mcwi+/+	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	5			45.7	mg/d	6.07	13.58	automated urine analysis				0				-	66892	717
SS-Apoeem7Mcwi-/-	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	5			33.37	mg/d	5.71	12.78	automated urine analysis				0				-	66902	717
SS-Bcas3em4Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	1	1/3 systolic pressure + 2/3 diastolic pressure		117.0	mmHg			radiotelemetry	carotid artery			0				-	66978	717
SS-Chr 5BN-Cyp4a2em1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	6	1/3 systolic pressure + 2/3 diastolic pressure		121.5	mmHg	1.31	3.21	radiotelemetry	carotid artery			0				-	66986	717
SS/JrSeac	body weight	controlled sodium content diet (0.3 %) (for 35 days)	Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1.	body mass	not specified	126 days	5			303.0	g	14.31	32.0	body weighing method		0.0		0					67255	733
BN/NHsdMcwi	ratio of change in renal blood flow rate to kidney weight	controlled sodium content diet (0.4 %) (for 16 hours) then norepinephrine (3 ug/kg/min) (for 0.1 hours)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	renal blood flow trait	female	97 days-101 days	19			-1.4	ml/min/g	0.2	0.87	electromagnetic flowmetry		0.0		0		electromagnetic flowmetry			67307	151
SS-Chr 5BN-Cyp4a2em1Mcwi+/+	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	3			1.25	g	0.06	0.11	post excision weight measurement				0				-	67016	717
SS-Nckap5em2Mcwi+/+	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	2			1.27	g	0.04	0.06	post excision weight measurement				0				-	67029	717
SS-Nox4em2Mcwi+/+	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	3			1.08	g	0.07	0.12	post excision weight measurement				0				-	67027	717
SS-Cybaem1Mcwi+/+	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	2			1.38	g	0.28	0.39	post excision weight measurement				0				-	67043	717
SS-Ncf2em1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	6			361.0	beats/min	11.06	27.09	radiotelemetry	carotid artery			0				-	67056	717
SS-Acad10em2Mcwi+/+	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	5			1.07	g	0.04	0.09	post excision weight measurement				0				-	67053	717
SS.LEW-(D17Chm14-D17Rat181)/Ayd	heart right ventricle weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	heart right ventricle mass	male	98 days	5			0.56	mg/g	0.1	0.22	post excision weight measurement		0		0					64907	226
SS.LEW-(D16Rat12-D16Chm23)/Ayd	heart left ventricle weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	heart left ventricle mass	male	98 days	10			3.54	mg/g	0.05	0.16	post excision weight measurement		0		0					64910	226
SS.LEW-(D16Rat38-D16Chm66)/Ayd	heart right ventricle weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	heart right ventricle mass	male	98 days	8			0.62	mg/g	0.02	0.06	post excision weight measurement		0		0					64913	226
SS.LEW-(D8Chm14-D8Rat16)/Ayd	heart left ventricle weight to body weight ratio	controlled sodium content diet (2 %) (between 35 and 98 days)	Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161	heart left ventricle mass	male	98 days	7			2.57	mg/g	0.05	0.13	post excision weight measurement		0		0					64933	226
SS/Jr	diastolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 47 days)	Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.	arterial blood pressure trait	male	114 days-116 days	3			158.2	mmHg	3.9	6.75	intra-aortic abdominal radiotelemetry		86400		0					65066	283
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 17 and 18 days)	Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.	arterial blood pressure trait	male	85 days-87 days	9			214.9	mmHg	8.9	26.7	tail cuff photoplethysmography		172800		0					65074	283
SS.SR-(D7Mco19-D7Mco7)/Jr	body weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days)	Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.	body mass	male	114 days-118 days	3			360.3	g	15.3	26.5	body weighing method		0		0					65099	283
SS-Alms1em1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	5			353.0	beats/min	13.56	30.32	radiotelemetry	carotid artery			0				-	67119	717
SS-Gpr183em1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	6			380.67	beats/min	11.11	27.22	radiotelemetry	carotid artery			0				-	67121	717
SS-Acad10em2Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	12			375.42	beats/min	9.61	33.28	radiotelemetry	carotid artery			0				-	67124	717
SS/Jr	systolic blood pressure	controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)	Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.	arterial blood pressure trait	male	64 days-72 days	20		serial mean	206.6	mmHg	2.4	10.73	tail cuff plethysmography		345600		0		Rats warmed to 28 degrees C for measurement.			65793	237
GH/OmrMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	7			-13.51	beats/min	6.01	15.9	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51710	481
SS-Chr 20BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	15			-83.44	beats/min	10.79	41.81	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51713	481
GH/OmrMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	7			-0.83	beats/min	8.19	21.68	vascular fluid filled catheter				0				Moms and pups used in studies were fed Teklad	51724	481
FHH/EurMcwi	urine total protein excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	total urine protein amount	female	87 days-120 days	7			19.85	mg/d	4.01	10.61	automated urine analysis				0				Moms and pups used in studies were fed Teklad	51749	481
LEW/Crl	heart rate	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	4			352.38	beats/min	10.21	20.42	vascular fluid filled catheter				0					51782	481
SS-Chr 16BN/Mcwi	creatinine clearance	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	glomerular filtration trait	male	87 days-120 days	10			2.35	ml/min	0.14	0.44	urine creatinine analysis				0				Moms and pups used in studies were fed Dyets	51802	481
SS/Hsd	plasma total cholesterol level	controlled sodium content diet (0.3 %) then fasting (for 16 hours)	Herrera VL, et al., Circ Res 2004 Mar 5; 94(4):446-52	blood cholesterol amount	male	180 days	20			171.81	mg/dl	6.95	31.08	plasma total cholesterol measurement test				0					11884	204
SS/JrHsdMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	3			23.81	mmHg	5.74	9.95	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51813	481
SS-Chr 18BN/Mcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	female	87 days-120 days	5			14.36	mmHg	3.33	7.45	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51816	481
Hsd:SD	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	20			11.22	beats/min	7.91	35.37	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	51875	481
FHH/EurMcwi	urine sodium excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	urine sodium amount	male	87 days-120 days	6			13.2	mEq/d	1.8	4.41	flame atomic emission spectrometry				0				Moms and pups used in studies were fed Teklad	51892	481
SS-Chr 18BN/Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	blood creatinine amount	female	87 days-120 days	1			0.35	mg/dl			radioimmunoassay				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51903	481
WKY/NCrl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	9			-14.79	mmHg	5.52	16.56	vascular fluid filled catheter				0					51914	481
SS/JrHsdMcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	heart pumping trait	male	87 days-120 days	3			1.67	beats/min	20.69	35.83	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51978	481
SS-Chr 16BN/Mcwi	absolute change in heart rate	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	heart pumping trait	female	87 days-120 days	2			-55.0	beats/min	29.4	41.58	vascular fluid filled catheter				0				Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks	51980	481
LEW/Crl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	9			1.65	mmHg	2.61	7.83	vascular fluid filled catheter				0					51994	481
SS/JrHsdMcwi	urine sodium excretion rate	controlled sodium content diet (4 %) (between 17 and 36 days)	PhysGen Renal A data	urine sodium amount	female	87 days-120 days	11			7.72	mEq/d	1.23	4.07	flame atomic emission spectrometry				0				Moms and pups used in studies were fed Dyets	52017	481
LEW/Crl	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours)	PhysGen Renal A data	arterial blood pressure trait	male	87 days-120 days	9			-0.47	mmHg	3.39	10.17	vascular fluid filled catheter				0					52025	481
FHH-Chr 18BN/Mcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	female	80 days-99 days	9			64.77	mg/d	14.16	42.49	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52114	482
FHH-Chr 10BN/Mcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	male	80 days-99 days	6			556.36	mg/d	51.87	127.06	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52133	482
SS-Chr 6BN/Mcwi	creatinine clearance	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	glomerular filtration trait	female	80 days-99 days	7			1.3	ml/min	0.1	0.28	urine creatinine analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52144	482
FHH-Chr 13BN/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	male	80 days-99 days	10			12.0	mEq/d	2.14	6.77	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52796	482
FHH-Chr 2BN/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	male	80 days-99 days	5			17.74	mEq/d	4.06	9.07	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52806	482
FHH-Chr 14BN/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	male	80 days-99 days	7			30.48	mEq/d	3.7	9.8	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52804	482
FHH-Chr XBN/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	male	80 days-99 days	7			19.66	mEq/d	2.76	7.3	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52815	482
FHH-Chr 9BN/Mcwi	urine sodium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine sodium amount	male	80 days-99 days	6			19.96	mEq/d	1.86	4.56	flame atomic emission spectrometry				0				Moms were fed Teklad, pups used in studies were fed Dyets	52823	482
SS-Chr 5BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	female	80 days-99 days	8			122.04	mmHg	2.16	6.11	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52842	482
SS.LEW-(D10Arb9-D10Rat57)/Mco	heart wet weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)	Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.	heart mass	male	68 days-70 days	20			1.1	g	0.02	0.08	digital scale post excision weight measurement		0		0					12682	282
SS.LEW-(D10Mco84-D10Got93)/Mco	body weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)	Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.	body mass	male	68 days-70 days	30			305.0	g	1.96	10.74	whole body digital scale		0		0					12706	282
SS.SHR-(D9Wox16-D9Rat64)/Mco	diastolic blood pressure	controlled sodium content diet (2 %) (between 35 and 37 days)	Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.	arterial blood pressure trait	male	75 days-79 days	5		serial mean	103.0	mmHg	1.15	2.57	intra-aortic abdominal radiotelemetry	lower abdominal aorta	172800		0		C-40 transmitter (Data Sciences International, St. Paul, MN)	average of 12 4-hour averages over 48 hours using 5 or 6 rats		13032	305
SS/Jr	urine albumin excretion rate	controlled sodium content diet (0.2 %)	Poyan Mehr A, et al., Physiol Genomics 2003 Aug 15;14(3):209-16.	urine albumin amount	not specified	28 days	12			4.7	mg/d			enzyme linked immunosorbent assay	urine	0.0		0		rat albumin ELISA			13281	335
SS.LEW-(D1Uia2-D1Rat49)/Jr	body weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)	Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.	body mass	male	68 days-70 days	20			307.0	g	5.02	22.45	body weighing method				0					12500	266
WKY	heart wet weight	controlled sodium content diet (0.4 %) (for 122 days) then controlled sodium content diet (1.4 %) (for 210 days)	Inomata H, et al., Hypertens Res 2005 Mar;28(3):273-81.	heart mass	female	360 days	4			0.55	g	0.02	0.04	post excision weight measurement		0		0					12594	268
SS.LEW-(D18Chm41-D18Rat45)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days)	Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8.	arterial blood pressure trait	male	56 days	5			130.0	mmHg	3.0	6.71	intra-aortic abdominal radiotelemetry	aorta			0					12597	269
SS.LEW-(D18Rat29-D18Rat55)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days)	Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8.	arterial blood pressure trait	male	56 days	11			148.0	mmHg	4.0	13.27	intra-aortic abdominal radiotelemetry	aorta			0					12607	269
SS.LEW-(D5Rat130-D5Rat31)/JrMcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 21 and 25 days)	Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5.	arterial blood pressure trait	male	82 days-86 days	32		serial mean	159.0	mmHg			vascular fluid filled catheter	femoral artery	345600		0		connected to solid-state transducer (Argon Medical Technologies, Athens, TX)	5 hr recording session - 1 min. averages, averaged over 4 days		12618	272
F344-Plce1Tn(sb-T2/Bart3)2.146Mcwi	body length, nose to tail	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	male	70 days-84 days	8			38.63	cm	0.49	1.38	in vivo ruler method				0					63664	529
FHH-Procm1Mcwi	body length, nose to tail	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	female	70 days-84 days	9			37.72	cm	1.43	4.28	in vivo ruler method				0					63678	529
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi	body length, nose to tail	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	female	70 days-84 days	8			33.13	cm	1.43	4.03	in vivo ruler method				0					63686	529
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi	body length, nose to tail	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	male	70 days-84 days	1			35.0	cm			in vivo ruler method				0					63694	529
FHH-Egln3m1Mcwi	body length, nose to tail	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	male	70 days-84 days	6			42.58	cm	0.42	1.02	in vivo ruler method				0					63705	529
FHH-Tlr4m1Mcwi	body length, nose to tail	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	male	70 days-84 days	12			40.83	cm	0.38	1.3	in vivo ruler method				0					63713	529
FHH-Egln3m1Mcwi	heart left ventricle wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart left ventricle mass	female	70 days-84 days	14			0.52	g	0.01	0.04	digital scale post excision weight measurement				0					63791	529
SS-Chr 5BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	male	80 days-99 days	7			130.42	mmHg	2.59	6.85	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52844	482
SS-Chr 13BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	male	80 days-99 days	18			143.27	mmHg	0.95	4.05	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52855	482
SS-Chr XBN/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	female	80 days-99 days	5			167.1	mmHg	9.3	20.79	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52861	482
SS-Chr 18BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	male	80 days-99 days	8			134.57	mmHg	2.52	7.13	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52858	482
SS-Chr 10BN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	male	80 days-99 days	11			1.26	mEq/d	0.21	0.69	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52927	482
SS-Chr YBN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	male	80 days-99 days	17			1.4	mEq/d	0.1	0.4	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52955	482
SS/JrHsdMcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	male	80 days-99 days	64			1.29	mEq/d	0.06	0.5	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52957	482
SS/JrHsdMcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	female	80 days-99 days	11			1.15	mEq/d	0.05	0.18	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52963	482
SS-Chr 4BN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	female	80 days-99 days	8			1.1	mEq/d	0.1	0.27	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52968	482
SS-Chr 1BN/Mcwi	creatinine clearance	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	glomerular filtration trait	male	80 days-99 days	14			2.08	ml/min	0.21	0.79	urine creatinine analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52172	482
SS-Chr 17BN/Mcwi	plasma creatinine level	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	blood creatinine amount	male	80 days-99 days	5			0.34	mg/dl	0.05	0.12	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52200	482
SS-Chr 15BN/Mcwi	plasma creatinine level	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	blood creatinine amount	male	80 days-99 days	7			0.36	mg/dl	0.02	0.06	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52208	482
SS-Chr 12BN/Mcwi	plasma creatinine level	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	blood creatinine amount	male	80 days-99 days	6			0.3	mg/dl	0.02	0.06	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52229	482
SS-Chr 1BN/Mcwi	plasma creatinine level	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	blood creatinine amount	male	80 days-99 days	14			0.33	mg/dl	0.02	0.07	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52221	482
LE/BluGill	plasma creatinine level	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	blood creatinine amount	male	80 days-99 days	6			0.32	mg/dl	0.02	0.05	radioimmunoassay				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	52240	482
FHH-Chr 6BN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	female	80 days-99 days	8			1.1	mEq/d	0.06	0.16	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52303	482
FHH-Chr YBN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	male	80 days-99 days	5			1.47	mEq/d	0.06	0.14	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52317	482
FHH-Chr 11BN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	female	80 days-99 days	6			0.62	mEq/d	0.16	0.4	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52328	482
FHH-Chr 4BN/Mcwi	urine potassium excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine potassium amount	female	80 days-99 days	9			0.97	mEq/d	0.1	0.29	flame atomic emission spectrometry				0		urine potassium analysis		Moms were fed Teklad, pups used in studies were fed Dyets	52325	482
FHH-Chr 6BN/Mcwi	creatinine clearance	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	glomerular filtration trait	male	80 days-99 days	9			1.69	ml/min	0.15	0.46	urine creatinine analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52348	482
FHH-Chr 4BN/Mcwi	creatinine clearance	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	glomerular filtration trait	male	80 days-99 days	5			0.98	ml/min	0.12	0.26	urine creatinine analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52369	482
SS/Jr	heart wet weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.	heart mass	male	64 days-66 days	20			1.35	g	0.01	0.04	post excision weight measurement		0		0					12845	313
SS.LEW-(D1Mco36-D1Rat131)/1Mco	heart wet weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.	heart mass	male	64 days-66 days	20			1.18	g	0.01	0.04	post excision weight measurement		0		0					12853	313
SS/Jr	body weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.	body mass	male	64 days-66 days	20			309.0	g	2.53	11.31	body weighing method		0		0					12864	313
SS.LEW-(D1Mco36-D1Mco101)/Mco	body weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.	body mass	male	64 days-66 days	30			323.0	g	2.25	12.32	body weighing method		0		0					12877	313
SS/Jr	heart weight to body weight ratio	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)	Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.	heart mass	male	64 days-66 days	20			4.04	g/kg	0.03	0.13	post excision weight measurement		0		0					12883	313
SHR	heart wet weight	controlled sodium content diet (0.4 %) (for 122 days) then controlled sodium content diet (1.4 %) (for 210 days)	Inomata H, et al., Hypertens Res 2005 Mar;28(3):273-81.	heart mass	female	360 days	4			0.68	g	0.05	0.09	post excision weight measurement		0		0					12576	268
SS/Jr	heart wet weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)	Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.	heart mass	male	68 days-70 days	20			1.31	g	0.02	0.07	digital scale post excision weight measurement		0		0					12667	282
SS.SR-(D7Mco19-D7Mco7)/Jr	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 26 and 27 days)	Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.	arterial blood pressure trait	male	42 days-69 days	14			170.8	mmHg	3.3	12.35	tail cuff photoplethysmography		172800		0					12678	283
SS.SHR-(D9Wox16-D9Mco77)/Mco	body weight	controlled sodium content diet (2 %) (for 28 days)	Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.	body mass	male	68 days-70 days	20			301.0	g	5.65	25.27	body weighing method				0					12951	305
SS.SHR-(D9Wox16-D9Rat64)/Mco	heart wet weight	controlled sodium content diet (2 %) (for 28 days)	Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.	heart mass	male	68 days-70 days	20			1.17	g	0.02	0.08	post excision weight measurement				0					12959	305
SS.SHR-(D9Rat7-D9Mco93)/Mco	body weight	controlled sodium content diet (2 %) (for 28 days)	Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.	body mass	male	68 days-70 days	20			314.0	g	2.76	12.34	body weighing method				0					12957	305
SS.BN-(D13Rat127-D13Rat61)/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 16 and 19 days)	Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12.	arterial blood pressure trait	male	86 days-89 days	12			187.0	mmHg	2.6	9.01	vascular fluid filled catheter	left femoral artery	14400		0		on 3 consecutive days			65181	15
FHH-Chr 12BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine albumin amount	male	80 days-99 days	11			111.94	mg/d	15.39	51.03	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52405	482
FHH-Chr 15BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	urine albumin amount	female	80 days-99 days	7			36.68	mg/d	12.67	33.51	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52408	482
SS-Chr 14BN/Mcwi	plasma renin activity level	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	renin activity	male	80 days-99 days	8			0.42	ng/ml/h	0.1	0.29	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52441	482
FHH-Chr 10BN/Mcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	male	80 days-99 days	5			406.89	beats/min	10.72	23.98	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52523	482
FHH-Chr XBN/Mcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	female	80 days-99 days	5			452.27	beats/min	6.2	13.85	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52526	482
FHH-Chr 17BN/Mcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	male	80 days-99 days	8			404.47	beats/min	25.87	73.18	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52515	482
FHH-Chr 7BN/Mcwi	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	male	80 days-99 days	9			429.18	beats/min	10.25	30.75	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52528	482
FHH-Chr 12BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	female	80 days-99 days	11			163.84	mmHg	7.46	24.74	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52531	482
FHH-Chr 7BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days)	PhysGen Renal B data	arterial blood pressure trait	male	80 days-99 days	9			185.36	mmHg	6.33	18.99	vascular fluid filled catheter				0				Moms were fed Teklad, pups used in studies were fed Dyets	52575	482
SS-Chr 10BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine albumin amount	female	80 days-99 days	10			26.81	mg/d	7.11	22.47	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52589	482
SS-Chr 7BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine albumin amount	female	80 days-99 days	11			15.16	mg/d	2.95	9.78	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52594	482
SS-Chr 1BN/Mcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine albumin amount	male	80 days-99 days	20			6.78	mg/d	1.12	5.0	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52611	482
SS/JrHsdMcwi	urine albumin excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	urine albumin amount	female	80 days-99 days	11			73.53	mg/d	19.27	63.93	radioimmunoassay				0				Moms were fed Teklad, pups used in studies were fed Dyets	52616	482
LE/BluGill	heart rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	heart pumping trait	male	80 days-99 days	7			382.48	beats/min	3.97	10.5	vascular fluid filled catheter				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	52630	482
SS-Chr 20BN/Mcwi	urine total protein excretion rate	controlled sodium content diet (8 %) (between 19 and 22 days)	PhysGen Renal B data	total urine protein amount	male	80 days-99 days	9			134.48	mg/d	19.15	57.45	automated urine total protein analysis				0				Moms were fed Teklad, pups used in studies were fed Dyets	52704	482
SS/Jr	systolic blood pressure	controlled sodium content diet (2 %) (between 25 and 28 days)	Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35.	arterial blood pressure trait	not specified	64 days-68 days	18		serial mean	217.0	mmHg	4.0	16.97	tail cuff plethysmography				0			average of 12 readings from 4 daily sessions		11831	148
SS.LEW-(D10Arb9-D10Got101)/Jr	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)	Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.	arterial blood pressure trait	male	64 days-70 days	20		serial mean	217.0	mmHg	4.28	19.14	tail cuff photoplethysmography	tail	345600		0			average of 4 daily averages of 3-4 measurements/day		13127	282
SS.LEW-(D10Rat29-D10Mco88)/Mco	systolic blood pressure	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)	Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.	arterial blood pressure trait	male	64 days-70 days	20		serial mean	191.0	mmHg	4.07	18.2	tail cuff photoplethysmography	tail	345600		0			average of 4 daily averages of 3-4 measurements/day		13135	282
SHRSR.SHRSP-(Klk1-Mt1-ps1)/Bbb	urine total protein excretion rate	controlled sodium content diet (3.7 mg/g) (for 84 days) and controlled sodium content drinking water (1 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days)	Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11.	total urine protein amount	not specified	126 days	26			294.0	mg/d	2.94	15.0	Bradford protein assay		0.0		0					69225	1126
BN/NHsdMcwi	urine sodium level	controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	urine sodium amount	female	92 days-94 days	22			100.4	mmol/l	6.5	30.49	unspecified method		0.0		0		urine sodium analysis			69466	151
SS/JrHsdMcwi	creatinine clearance	controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	glomerular filtration trait	female	92 days-94 days	10			1.08	ml/min	0.37	1.17	urine creatinine analysis		0.0		0			mg/min		69480	151
SS/Jr	heart left ventricle end-diastolic diameter	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	heart left ventricle end-diastolic diameter	male	77 days	40			7.18	mm	0.09	0.57	transthoracic echocardiography		0.0		0					68266	542
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb	urine total protein excretion rate	controlled sodium content diet (3.7 mg/g) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days)	Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11.	total urine protein amount	not specified	98 days	3			351.0	mg/d	28.87	50.0	Bradford protein assay		0.0		0					70260	1126
SS.MNS-(D2Mit6-D2Rat303)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days)	Dutil J, et al., Physiol Genomics 2005 Mar 1;.	arterial blood pressure trait	male	68 days-98 days	9			168.0	mmHg			radiotelemetry		0.0		0					69028	1096
SS.MNS-(D2Mit6-Adh1)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days)	Dutil J, et al., Physiol Genomics 2005 Mar 1;.	arterial blood pressure trait	male	68 days-98 days	5			120.0	mmHg			radiotelemetry		0.0		0					69026	1096
SS.MNS-(D2Mit6-D2Rat166)/Ayd	heart left ventricle deoxyribonucleic acid level to body weight ratio	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days)	Dutil J, et al., Physiol Genomics 2005 Mar 1;.	heart left ventricle DNA amount	male	98 days	4			5.0	ug/g	0.5	1.0	spectrophotometry		0.0		0					69036	1096
BN/NHsdMcwi	heart rate	controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	heart pumping trait	female	93 days	20		serial mean	369.9	beats/min	5.1	22.81	vascular indwelling catheter method	left femoral artery	10800.0		0					69519	151
F344-Plcb3Tn(sb-T2/Bart3)2.69Mcwi	serum alkaline phosphatase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	female	70 days-84 days	3			114.33	U/l	8.84	15.31	standard blood chemistry panel				0					60436	527
FHH-Lcatm1Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	15			17.73	pg	0.15	0.58	automated blood cell counting method				0					60471	527
FHH-Ccr2m1Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	5			18.02	pg	0.1	0.22	automated blood cell counting method				0					60480	527
BN-Lcatm3Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	2			17.25	pg	0.15	0.21	automated blood cell counting method				0					60504	527
BN-Lcatm3Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	1			17.3	pg			automated blood cell counting method				0					60507	527
F344-Nrg1Tn(sb-T2/Bart3)2.183Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	5			18.16	pg	0.17	0.39	automated blood cell counting method				0					60526	527
F344-Nrg1Tn(sb-T2/Bart3)2.183Mcwi	mean corpuscular hemoglobin	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	5			17.78	pg	0.22	0.5	automated blood cell counting method				0					60529	527
SS-Sod3m1Mcwi	serum total cholesterol level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood cholesterol amount	male	70 days-84 days	10			101.4	mg/dl	9.38	29.66	standard blood chemistry panel				0					60534	527
SS-Ghsrm3Mcwi	serum total cholesterol level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood cholesterol amount	male	70 days-84 days	2			107.0	mg/dl	7.0	9.9	standard blood chemistry panel				0					60531	527
FHH-Adipoqm1Mcwi	red blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	female	70 days-84 days	9			7.5	x 10E6 cells/ul	0.09	0.26	automated blood cell counting method				0					60542	527
SS	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days)	Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.	arterial blood pressure trait	male	66 days-80 days	21			177.0	mmHg			intra-aortic abdominal radiotelemetry	abdominal aorta	0.0		0					70468	1438
SS.LEW-(D5Mco39-D5Mco57)/2Mco	systolic blood pressure	controlled sodium content diet (2 %) (between 24 and 28 days)	Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11.	arterial blood pressure trait	male	62 days-66 days	0			221.0	mmHg	6.3		tail cuff plethysmography		0.0		0		restrained, 28 degrees C			70589	1482
BN/NHsdMcwi	diastolic blood pressure	controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) then controlled exposure to darkness (for 12 hours)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	arterial blood pressure trait	female	89 days-91 days	20		serial mean	96.0	mmHg	2.7	12.07	vascular indwelling catheter method	left femoral artery	0.0		0					69445	151
SS/JrTol	systolic blood pressure	controlled sodium content diet (2 %) (between 24 and 28 days)	Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11.	arterial blood pressure trait	male	62 days-66 days	0			220.0	mmHg	5.6		tail cuff plethysmography		0.0		0		restrained, 28 degrees C			70581	1482
SS-Plcd3em7Mcwi+/+	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	3			1.36	g	0.2	0.35	digital scale post excision weight measurement				0				-	44360	441
SS-Nppbem2Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	16			1.54	g	0.03	0.13	digital scale post excision weight measurement				0				-	44371	441
SS-Nppaem4Mcwi+/+	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	2			1.38	g	0.04	0.05	digital scale post excision weight measurement				0				-	44379	441
SS-Nppbem4Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	9	1/3 systolic pressure + 2/3 diastolic pressure		130.0	mmHg	4.04	12.11	radiotelemetry	carotid artery			0				-	44392	441
SS-Slc30a8em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	1/3 systolic pressure + 2/3 diastolic pressure		137.5	mmHg	4.48	8.96	radiotelemetry	carotid artery			0				-	44395	441
SS-Ulk3em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	3	1/3 systolic pressure + 2/3 diastolic pressure		129.0	mmHg	6.25	10.82	radiotelemetry	carotid artery			0				-	44419	441
SS-Aldh2em2Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	6	1/3 systolic pressure + 2/3 diastolic pressure		144.67	mmHg	11.55	28.3	radiotelemetry	carotid artery			0				-	44421	441
SS-Cdh13em1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	7	1/3 systolic pressure + 2/3 diastolic pressure		142.57	mmHg	5.49	14.51	radiotelemetry	carotid artery			0				-	44437	441
SS-Stk39em2Mcwi-/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	1			1.68	g			digital scale post excision weight measurement				0				-	44461	441
SS-Mstnem1Mcwi-/-	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	13			1.43	g	0.02	0.07	digital scale post excision weight measurement				0				-	44459	441
SS-Mstnem3Mcwi-/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	1			1.55	g			digital scale post excision weight measurement				0				-	44467	441
SS-Ulk3em1Mcwi+/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	3			1.58	g	0.09	0.15	digital scale post excision weight measurement				0				-	44480	441
SS-Stk39em2Mcwi-/-	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	9			1.32	g	0.02	0.07	digital scale post excision weight measurement				0				-	44493	441
SS-Msraem3Mcwi-/-	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	3			1.53	g	0.07	0.12	digital scale post excision weight measurement				0				-	44501	441
SS.LEW-(D18Chm59-D18Rat1)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days)	Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.	arterial blood pressure trait	male	66 days-80 days	5			142.0	mmHg	2.0	4.47	intra-aortic abdominal radiotelemetry	abdominal aorta	0.0		0					84484	1438
SS.LEW-(D10Rat119-D10Mgh1)/Ayd	mean arterial blood pressure	controlled sodium content diet (2 %) (for 21 days)	Charron S, et al., Hypertension. 2005 Dec;46(6):1300-8. Epub 2005 Nov 14.	arterial blood pressure trait	male	56 days-59 days	10			107.0	mmHg			intra-aortic abdominal radiotelemetry		86400.0		0					67877	830
SS.LEW-(D10Rat204-D10Rat9)/Ayd	mean arterial blood pressure	controlled sodium content diet (2 %) (for 21 days)	Charron S, et al., Hypertension. 2005 Dec;46(6):1300-8. Epub 2005 Nov 14.	arterial blood pressure trait	male	56 days-59 days	5			146.0	mmHg			intra-aortic abdominal radiotelemetry		86400.0		0					67888	830
SR/Hsd	cubic root of body weight to nasoanal length ratio	controlled sodium content diet (0.3 %) then fasting (for 16 hours)	Herrera VL, et al., Circ Res 2004 Mar 5; 94(4):446-52	body mass	female	180 days	14			306.0	g/mm x 10000	2.0	7.48	body weighing method		0.0		0					67894	204
SS.LEW-(D16Rat112-D16Chm60)/Ayd	heart left atrium end-diastolic diameter	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	heart left atrium diameter	male	77 days	14			3.29	mm	0.12	0.46	transthoracic echocardiography		0.0		0					68311	542
SS/Jr	heart isovolumetric relaxation time	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	heart muscle relaxation trait	male	77 days	40			20.1	ms	0.41	2.57	continuous wave doppler ultrasound		0.0		0			isovolumetric relaxation time		68314	542
SS.LEW-(D18Chm41-D18Rat92)/Ayd	heart left atrium fractional shortening	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	heart left atrium diameter	male	77 days	8	(LADs - LADd)/ LADs x 100		38.1	%	1.62	4.58	transthoracic echocardiography		0.0		0			heart left atrium fractional shortening		68324	542
SS/JrHsd	heart weight to body weight ratio	controlled sodium content diet (8 %) (for 84 days)	Herrera VL, et al., Physiol Genomics. 2006 Aug 16;26(3):172-9. Epub 2006 May 23.	heart mass	female	168 days	8			3.65	g/kg	0.11	0.31	post excision weight measurement		0.0		0					67868	810
SS.LEW-(D10Chm10-D10Rat11)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days)	Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.	arterial blood pressure trait	male	66 days-80 days	6			151.0	mmHg	3.0	7.35	intra-aortic abdominal radiotelemetry	abdominal aorta	0.0		0					70439	1438
SS.LEW-(D16Chm48-D16Chm60)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days)	Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.	arterial blood pressure trait	male	66 days-80 days	7			134.0	mmHg	5.0	13.23	intra-aortic abdominal radiotelemetry	abdominal aorta	0.0		0					70447	1438
SS-Chr 12BN/Mcwi	mean arterial blood pressure	controlled sodium content diet (1 %) (for 77 days)	Flister MJ, et al., Hypertension. 2012 Oct;60(4):942-8. doi: 10.1161/HYPERTENSIONAHA.112.198200. Epub 2012 Aug 6.	arterial blood pressure trait	male	67 days-77 days	10		serial mean	127.0	mmHg	1.0	3.16	intra-aortic abdominal radiotelemetry		14400.0		0		abdominal aorta	4 hrs for 3 consecutive days		96862	1718
FHH-F10m2Mcwi	serum albumin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood albumin amount	male	70 days-84 days	16			3.81	g/dl	0.06	0.22	standard blood chemistry panel				0					61920	527
BN/NHsdMcwi	serum albumin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood albumin amount	male	70 days-84 days	44			3.89	g/dl	0.03	0.23	standard blood chemistry panel				0					61961	527
FHH-Lcatm1Mcwi	serum aspartate aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood aspartate transaminase amount	female	70 days-84 days	15			175.87	U/l	20.14	78.0	standard blood chemistry panel				0					61977	527
F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi	serum aspartate aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood aspartate transaminase amount	male	70 days-84 days	3			87.33	U/l	34.52	59.79	standard blood chemistry panel				0					61988	527
F344/NHsd	serum aspartate aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood aspartate transaminase amount	male	70 days-84 days	7			186.0	U/l	21.39	56.59	standard blood chemistry panel				0					61991	527
BN-Lcatm3Mcwi	serum aspartate aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood aspartate transaminase amount	male	70 days-84 days	1			183.0	U/l			standard blood chemistry panel				0					62013	527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi	serum aspartate aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood aspartate transaminase amount	female	70 days-84 days	2			202.0	U/l	44.0	62.23	standard blood chemistry panel				0					62029	527
SS-Cpt2m1Mcwi	blood lymphocyte count	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	lymphocyte quantity	female	70 days-84 days	1			4.68	x 1000 cells/ul			automated blood cell counting method				0					62043	527
SS-Ulk4em3Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	1/3 systolic pressure + 2/3 diastolic pressure		172.5	mmHg	13.73	27.45	radiotelemetry	carotid artery			0				-	66633	717
SS-Tgfb1em3Mcwi+/-	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	3			1.09	g	0.06	0.1	post excision weight measurement				0				-	67005	717
SR/Hsd	absolute change in mean arterial blood pressure	controlled sodium content diet (4 %) then 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg)	Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1.	arterial blood pressure trait	male	35 days-56 days	0			-39.0	mmHg	1.0		tail cuff plethysmography		0.0		0				DR strain is from Charles River Laboratory, Wilmington, MA	67235	731
SR/Hsd	absolute change in mean arterial blood pressure	controlled sodium content diet (0.15 %) then ruthenium red (3 mg/kg) then 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg)	Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1.	arterial blood pressure trait	male	35 days-56 days	0			-5.0	mmHg	3.0		tail cuff plethysmography		0.0		0				DR strain is from Charles River Laboratory, Wilmington, MA	67239	731
SS/HsdMcwiCrl	absolute change in mean arterial blood pressure	controlled sodium content diet (0.15 %) then ruthenium red (3 mg/kg) then 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg)	Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1.	arterial blood pressure trait	male	35 days-56 days	0			-5.0	mmHg	2.0		tail cuff plethysmography		0.0		0				DR strain is from Charles River Laboratory, Wilmington, MA	67241	731
SS-Agtr1aem1Mcwi-/-	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	9			1.19	g	0.03	0.09	digital scale post excision weight measurement				0				-	44558	441
SS-Mstnem3Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	7			369.29	beats/min	4.47	11.81	radiotelemetry	carotid artery			0				-	44603	441
SS-Slc30a8em2Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	1			344.0	beats/min			radiotelemetry	carotid artery			0				-	44614	441
SS-Prokr1em2Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	6			389.17	beats/min	12.11	29.66	radiotelemetry	carotid artery			0				-	44630	441
SS-Cdh13em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	4			357.75	beats/min	16.57	33.14	radiotelemetry	carotid artery			0				-	44640	441
SS-Plcd3em4Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	13			356.0	beats/min	5.5	19.85	radiotelemetry	carotid artery			0				-	44654	441
SS-Plod1em1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	11			362.7	beats/min	7.75	25.71	radiotelemetry	carotid artery			0				-	44656	441
SS-Aldh2em2Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	6			401.17	beats/min	22.89	56.07	radiotelemetry	carotid artery			0				-	44667	441
LEW	peak aortic velocity	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	aorta blood flow trait	male	77 days	14			94.6	cm/s	3.1	11.6	pulsed wave doppler ultrasound		0.0		0			peak aortic velocity		68241	542
SS.LEW-(D10Got112-Igfbp4)/Ayd	heart left ventricle anterior wall thickness	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)	Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.	heart left ventricle anterior wall thickness	male	77 days	5			0.15	mm	0.0	0.01	transthoracic echocardiography		0.0		0					68255	542
SS.LEW-(D2Uia5-D2Mit6)(D10Rat194-D10Chm243)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days)	Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.	arterial blood pressure trait	male	66 days-80 days	6			183.0	mmHg	9.0	22.05	intra-aortic abdominal radiotelemetry	abdominal aorta	0.0		0					84497	1438
SS.LEW-(D10Chm10-D10Rat11)(D10Chm246-D10Chm257)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days)	Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.	arterial blood pressure trait	male	66 days-80 days	5			151.0	mmHg	4.0	8.94	intra-aortic abdominal radiotelemetry	abdominal aorta	0.0		0					84486	1438
SS.LEW-(D1Chm64-D1Rat19)(D10Rat194-D10Chm243)(D10Chm10-D10Rat11)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 10 and 24 days)	Chauvet C, et al., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.	arterial blood pressure trait	male	66 days-80 days	5			118.0	mmHg	3.0	6.71	intra-aortic abdominal radiotelemetry	abdominal aorta	0.0		0					84502	1438
SS.SHR-(D9Mco72-D9Mco105)/Mco	heart left ventricle end-systolic area	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %)	Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.	heart left ventricle size trait	not specified	0 days	7			0.44	cm2	0.05	0.13	echocardiography		0.0		0					69603	749
FHH/EurMcwi	blood neutrophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	neutrophil quantity	female	70 days-84 days	25			0.87	x 1000 cells/ul	0.13	0.64	automated blood cell counting method				0					60871	527
SS/JrHsdMcwi	serum sodium level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	male	70 days-84 days	40			143.98	mmol/l	0.37	2.33	flame atomic emission spectrometry				0					60901	527
FHH-Tgfbr2m2Mcwi	serum globulin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood globulin amount	male	70 days-84 days	11			1.65	g/dl	0.05	0.16	standard blood chemistry panel				0			replaced obsolete serum globulin level term, 1/19/2016		60912	527
F344-Plce1Tn(sb-T2/Bart3)2.146Mcwi	serum globulin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood globulin amount	female	70 days-84 days	5			1.9	g/dl	0.1	0.23	standard blood chemistry panel				0			replaced obsolete serum globulin level term, 1/19/2016		60928	527
WKY/NCrl	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	15			1.28	g/mg	0.11	0.41	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56861	522
LEW/Crl	sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	23			99.43	%	0.27	1.31	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56852	522
LE/BluGill	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	15			2.3	g/mg	0.16	0.62	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56866	522
Crl:CD(SD)	sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	9			98.22	%	0.64	1.92	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56855	522
SS-Chr 18BN/Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	10			0.1	umol/l	0.02	0.06	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	56874	522
GH/OmrMcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	10			0.1	umol/l	0.04	0.12	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	56880	522
SS-Chr 11BN/Mcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	8			-6.84	null	0.04	0.11	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56953	522
SS-Chr 18BN/Mcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	18			-7.14	null	0.05	0.21	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56958	522
BN/NHsdMcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	18			-6.67	null	0.11	0.48	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56975	522
SS-Chr XBN/Mcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	9			-6.79	null	0.07	0.2	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56977	522
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi	serum urea nitrogen level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood urea nitrogen amount	female	70 days-84 days	2			26.5	mg/dl	0.5	0.71	standard blood chemistry panel				0					60202	527
F344-Nrg1Tn(sb-T2/Bart3)2.183Mcwi	serum urea nitrogen level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood urea nitrogen amount	female	70 days-84 days	5			24.2	mg/dl	2.54	5.67	standard blood chemistry panel				0					60208	527
FHH-Nr0b2m1Mcwi	serum calcium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood calcium amount	female	70 days-84 days	6			9.73	mg/dl	0.12	0.29	standard blood chemistry panel				0					60213	527
SS/JrHsdMcwi	total white blood cell count	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	leukocyte quantity	male	70 days-84 days	39			8.01	x 1000 cells/ul	0.29	1.79	automated blood cell counting method				0					60287	527
FHH-Tgfbr2m2Mcwi	blood hemoglobin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	13			14.72	g/dl	0.18	0.66	automated blood cell counting method				0					60298	527
SS-Ghsrm3Mcwi	total white blood cell count	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	leukocyte quantity	female	70 days-84 days	1			7.1	x 1000 cells/ul			automated blood cell counting method				0					60292	527
FHH-Nr0b2m1Mcwi	blood hemoglobin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	6			13.62	g/dl	0.16	0.39	automated blood cell counting method				0					60295	527
FHH-F10m1Mcwi	blood hemoglobin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	11			13.51	g/dl	0.17	0.55	automated blood cell counting method				0					60317	527
FHH-Nr4a1m1Mcwi	blood hemoglobin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	11			14.21	g/dl	0.14	0.46	automated blood cell counting method				0					60325	527
SS-Mmp2em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	1	/3 systolic pressure + 2/3 diastolic pressure		139.0	mmHg			radiotelemetry	carotid artery			0				-	66472	717
SS-Nckap5em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	5	/3 systolic pressure + 2/3 diastolic pressure		144.4	mmHg	13.28	29.7	radiotelemetry	carotid artery			0				-	66475	717
SS-Nox4em2Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	/3 systolic pressure + 2/3 diastolic pressure		118.75	mmHg	1.8	3.59	radiotelemetry	carotid artery			0				-	66486	717
FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi+/+	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	5			43.77	mg/d	13.05	29.18	automated urine analysis				0				-	66507	717
SS-Nckap5em1Mcwi-/-	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	7			112.23	mg/d	36.1	95.51	automated urine analysis				0				-	66518	717
FHH-Chr 1BN-Sorcs1em1Mcwi-/-	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	12			37.54	mg/d	4.94	17.12	automated urine analysis				0				-	66526	717
SS-Nckap5em2Mcwi-/-	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	8			259.44	mg/d	39.72	112.35	automated urine analysis				0				-	66523	717
SS-Gpr183em2Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			349.5	beats/min	11.5	16.26	radiotelemetry	carotid artery			0				-	66585	717
SS-Mmp2em2Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	1			343.0	beats/min			radiotelemetry	carotid artery			0				-	66598	717
F344-Plcb3Tn(sb-T2/Bart3)2.69Mcwi	blood hemoglobin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	3			13.2	g/dl	0.92	1.59	automated blood cell counting method				0					60344	527
FHH-Tlr4m1Mcwi	blood hemoglobin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	9			14.56	g/dl	0.34	1.02	automated blood cell counting method				0					60358	527
BN/NHsdMcwi	blood hemoglobin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	43			14.87	g/dl	0.11	0.74	automated blood cell counting method				0					60363	527
FHH-Adipoqm1Mcwi	serum alkaline phosphatase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	female	70 days-84 days	9			140.11	U/l	18.98	56.94	standard blood chemistry panel				0					60388	527
FHH-Tgfbr2m2Mcwi	serum alkaline phosphatase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	female	70 days-84 days	10			171.8	U/l	7.12	22.52	standard blood chemistry panel				0					60396	527
SS-Cpt2m1Mcwi	mean corpuscular hemoglobin concentration	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	1			31.8	g/dl			automated blood cell counting method				0					61859	527
FHH-Lcatm1Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	8			0.02	umol/l	0.01	0.02	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62737	528
FHH-Adipoqm2Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	15			0.02	umol/l	0.0	0.01	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62734	528
BN-Tgfbr2m1Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	2			0.02	umol/l	0.0	0.01	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62748	528
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	2			0.01	umol/l	0.0	0.0	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62742	528
FHH-Htr1am1Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	12			0.03	umol/l	0.01	0.03	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62756	528
FHH-Procm1Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	15			0.03	umol/l	0.01	0.04	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62762	528
BN-Lcatm3Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	5			0.02	umol/l	0.01	0.02	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62775	528
FHH-Adra1am1Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours)	PhysGen Biochemistry data	blood creatinine amount	male	70 days-84 days	8			0.23	mg/dl	0.03	0.07	automated plasma creatinine analysis				0					61047	527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours)	PhysGen Biochemistry data	blood creatinine amount	female	70 days-84 days	2			0.25	mg/dl	0.05	0.07	automated plasma creatinine analysis				0					61055	527
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi	plasma creatinine level	controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours)	PhysGen Biochemistry data	blood creatinine amount	female	70 days-84 days	2			0.4	mg/dl	0.1	0.14	automated plasma creatinine analysis				0					61052	527
FHH-Agtr1bm1Mcwi	plasma anion gap	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	ion homeostasis trait	male	70 days-84 days	14			25.5	mmol/l	0.5	1.87	standard blood chemistry panel				0					61071	527
F344-DccTn(sb-T2/Bart3)2.205Mcwi	mean corpuscular hemoglobin concentration	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	6			32.5	g/dl	0.3	0.73	automated blood cell counting method				0					61187	527
F344-Plcb3Tn(sb-T2/Bart3)2.69Mcwi	mean corpuscular hemoglobin concentration	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	female	70 days-84 days	3			31.73	g/dl	0.42	0.72	automated blood cell counting method				0					61184	527
FHH/EurMcwi	mean corpuscular hemoglobin concentration	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	158			33.18	g/dl	0.07	0.93	automated blood cell counting method				0					61190	527
F344-Inpp4bTn(sb-T2/Bart3)2.143Mcwi	mean corpuscular hemoglobin concentration	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood hemoglobin amount	male	70 days-84 days	7			32.47	g/dl	0.14	0.36	automated blood cell counting method				0					61201	527
SS-Nppbem2Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	4			8.93	mEq/d	1.6	3.19	automated urine analysis				0				-	44204	441
SS-Prokr1em2Mcwi-/-	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	8			7.76	mEq/d	0.89	2.52	automated urine analysis				0				-	44225	441
SS-Aldh2em2Mcwi-/-	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	7			9.99	mEq/d	1.19	3.15	automated urine analysis				0				-	44231	441
SS-Plod1em1Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	5			8.04	mEq/d	1.21	2.7	automated urine analysis				0				-	44241	441
SS-Slc30a8em2Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	1			9.6	mEq/d			automated urine analysis				0				-	44244	441
SS-Nppaem4Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	2			9.78	mEq/d	0.49	0.69	automated urine analysis				0				-	44255	441
SS-Nppbem4Mcwi+/+	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	9			36.09	mg/d	5.74	17.23	automated urine analysis				0				-	44268	441
SS-Plcd3em4Mcwi-/-	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	13			56.8	mg/d	8.54	30.8	automated urine analysis				0				-	44284	441
SS-Agtr1aem1Mcwi-/-	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	9			52.39	mg/d	12.72	38.17	automated urine analysis				0				-	44311	441
SS-Stk39em2Mcwi-/-	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	10			16.55	mg/d	3.54	11.19	automated urine analysis				0				-	44308	441
SS-Agtrapem8Mcwi+/+	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	2			18.39	mg/d	6.69	9.46	automated urine analysis				0				-	44305	441
SS-Cyp1a1em5Mcwi+/+	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	2			1.32	g	0.02	0.03	digital scale post excision weight measurement				0				-	44327	441
Hsd:SD	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	14			-6.98	null	0.11	0.4	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan	57194	522
FHH-Adipoqm2Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Vascular data	body mass	female	70 days-84 days	15			194.2	g	3.74	14.48	whole body digital scale				0					62900	528
SS-Cpt2m1Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (1 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	2			-7.5	null	0.05	0.06	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		62894	528
SS-Cpt2m1Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (1 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	5			-7.68	null	0.09	0.2	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		62889	528
SS/JrHsdMcwi	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (1 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	5			-7.25	null	0.1	0.22	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62886	528
SS-Sod3m1Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (1 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	13			-8.1	null	0.03	0.12	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		62897	528
F344-Elmod3Tn(sb-T2/Bart3)2.42Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Vascular data	body mass	female	70 days-84 days	3			150.33	g	0.67	1.15	whole body digital scale				0					62911	528
FHH-F10m1Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Vascular data	body mass	female	70 days-84 days	7			188.57	g	4.12	10.89	whole body digital scale				0					62919	528
FHH-Htr1am1Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Vascular data	body mass	female	70 days-84 days	13			180.77	g	3.57	12.87	whole body digital scale				0					62922	528
F344-Plce1Tn(sb-T2/Bart3)2.146Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Vascular data	body mass	female	70 days-84 days	5			173.8	g	4.47	9.99	whole body digital scale				0					62916	528
BN-Lcatm3Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Vascular data	body mass	female	70 days-84 days	6			158.83	g	3.63	8.89	whole body digital scale				0					62941	528
FHH-Nr4a1m1Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	4			1.19	E-7mole	0.57	1.13	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63024	528
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	2			2.93	E-7mole	0.91	1.28	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63032	528
FHH-Adipoqm3Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	5			3.67	E-7mole	1.0	2.24	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63037	528
FHH-Slc8a2m1Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	15			1.12	E-7mole	0.18	0.71	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63045	528
FHH-Htr1am1Mcwi	serum total protein level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood total protein amount	female	70 days-84 days	13			5.27	g/dl	0.06	0.22	standard blood chemistry panel				0					61242	527
BN-Tgfbr2m1Mcwi	serum total protein level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood total protein amount	male	70 days-84 days	7			5.73	g/dl	0.06	0.16	standard blood chemistry panel				0					61234	527
FHH-Procm1Mcwi	serum total protein level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood total protein amount	male	70 days-84 days	10			5.27	g/dl	0.1	0.3	standard blood chemistry panel				0					61248	527
FHH-F10m2Mcwi	serum total protein level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood total protein amount	female	70 days-84 days	12			5.3	g/dl	0.09	0.3	standard blood chemistry panel				0					61253	527
FHH-Adipoqm3Mcwi	serum potassium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	male	70 days-84 days	5			6.06	mmol/l	0.49	1.09	flame atomic emission spectrometry				0					61343	527
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi	serum potassium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	male	70 days-84 days	4			4.0	mmol/l	0.22	0.43	flame atomic emission spectrometry				0					61360	527
BN/NHsdMcwi	serum potassium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	male	70 days-84 days	43			4.8	mmol/l	0.09	0.62	flame atomic emission spectrometry				0					61357	527
FHH-Adipoqm2Mcwi	total white blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	leukocyte quantity	female	70 days-84 days	12			4.16	x 1000 cells/ul	0.27	0.94	automated blood cell counting method				0					61363	527
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi	total white blood cell count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	leukocyte quantity	male	70 days-84 days	2			5.2	x 1000 cells/ul	0.5	0.71	automated blood cell counting method				0					61395	527
GH/OmrMcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	8			1.1	E-7mole	0.23	0.65	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	54598	522
LE/BluGill	logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	14			-7.41	null	0.09	0.33	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	54748	522
FHH-Chr 5BN/Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	9			82.78	%	2.73	8.18	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54759	522
FHH-Chr 15BN/Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	9			86.44	%	3.85	11.54	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54772	522
FHH-Chr 12BN/Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	16			60.88	%	4.67	18.66	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54770	522
SS-Chr 16BN/Mcwi	logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	9			-8.96	null	0.17	0.51	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56022	522
FHH-Chr 1BN/Mcwi	logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	18			-8.5	null	0.12	0.5	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56032	522
SS-Chr 5BN/Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	7			-7.35	null	0.08	0.21	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter	Moms and pups used in studies were fed Teklad	56112	522
FHH-Chr 13BN/Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	12			-8.2	null	0.09	0.31	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter	Moms and pups used in studies were fed Teklad	56131	522
FHH-Chr 20BN/Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	10			-7.77	null	0.08	0.26	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter	Moms and pups used in studies were fed Teklad	56134	522
FHH-Chr 9BN/Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	9			-8.39	null	0.17	0.51	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter	Moms and pups used in studies were fed Teklad	56169	522
FHH/EurMcwi	sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	10			100.0	%	0.0	0.0	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	56200	522
F344-Plcb3Tn(sb-T2/Bart3)2.69Mcwi	serum chloride level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood chloride amount	male	70 days-84 days	1			104.0	mmol/l			standard blood chemistry panel				0					62329	527
FHH-Adipoqm1Mcwi	serum total cholesterol level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood cholesterol amount	female	70 days-84 days	8			65.0	mg/dl	2.52	7.13	standard blood chemistry panel				0					62356	527
FHH-Tgfbr2m2Mcwi	serum total cholesterol level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood cholesterol amount	female	70 days-84 days	11			62.0	mg/dl	2.08	6.88	standard blood chemistry panel				0					62364	527
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi	serum total cholesterol level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood cholesterol amount	male	70 days-84 days	2			73.0	mg/dl	12.0	16.97	standard blood chemistry panel				0					62389	527
F344-DccTn(sb-T2/Bart3)2.205Mcwi	serum total cholesterol level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood cholesterol amount	female	70 days-84 days	4			74.5	mg/dl	7.1	14.2	standard blood chemistry panel				0					62394	527
FHH-Ghsrm1Mcwi	serum total cholesterol level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood cholesterol amount	male	70 days-84 days	15			61.67	mg/dl	1.43	5.52	standard blood chemistry panel				0					62405	527
BN-Lcatm3Mcwi	serum total cholesterol level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood cholesterol amount	female	70 days-84 days	2			38.5	mg/dl	1.5	2.12	standard blood chemistry panel				0					62400	527
SS-Cpt2m1Mcwi	serum total protein level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood total protein amount	male	70 days-84 days	6			5.78	g/dl	0.08	0.19	standard blood chemistry panel				0					62438	527
SS-Cpt2m1Mcwi	serum total bilirubin level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bilirubin amount	female	70 days-84 days	1			0.1	mg/dl			standard blood chemistry panel				0					62433	527
FHH-Adipoqm2Mcwi	serum glucose level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood glucose amount	female	70 days-84 days	12			129.58	mg/dl	10.37	35.91	standard blood chemistry panel				0					62449	527
FHH-Slc8a2m1Mcwi	serum glucose level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood glucose amount	female	70 days-84 days	12			122.0	mg/dl	11.39	39.45	standard blood chemistry panel				0					62460	527
FHH-Nr0b2m1Mcwi	serum glucose level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood glucose amount	male	70 days-84 days	10			157.5	mg/dl	9.05	28.62	standard blood chemistry panel				0					62463	527
F344-Plce1Tn(sb-T2/Bart3)2.146Mcwi	serum glucose level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood glucose amount	female	70 days-84 days	5			137.6	mg/dl	6.83	15.27	standard blood chemistry panel				0					62466	527
FHH-Ccr2m1Mcwi	serum glucose level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood glucose amount	female	70 days-84 days	5			111.2	mg/dl	14.76	33.0	standard blood chemistry panel				0					62468	527
FHH-Chr 11BN/Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	9			75.22	%	6.93	20.79	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54827	522
SS-Chr 4BN/Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	10			79.2	%	5.69	17.99	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54833	522
SS.BN-(D8Rat163-D8Rat81)/Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	9			49.44	%	5.26	15.77	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54838	522
BN/NHsdMcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	20			66.8	%	3.88	17.34	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54841	522
FHH-Chr 1BN/Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	18			41.5	%	5.45	23.12	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54846	522
SS-Chr 18BN/Mcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	8			29.13	%	2.86	8.08	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	54852	522
FHH/EurMcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	10			33.6	%	6.45	20.39	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	54855	522
SHR/NCrl	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	10			6.4	%	3.45	10.9	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	54857	522
SS.BN-(D12Arb13-D12Rat79)/Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	15			0.07	umol/l	0.02	0.06	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54890	522
FHH-Chr 17BN/Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	10			0.01	umol/l	0.0	0.01	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54909	522
FHH-Chr 19BN/Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	10			0.09	umol/l	0.08	0.26	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54926	522
SS-Chr 13BN/Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	10			0.01	umol/l	0.0	0.01	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54940	522
FHH-Chr 4BN/Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	10			0.02	umol/l	0.01	0.02	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54950	522
FHH-Chr 11BN/Mcwi	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	10			0.01	umol/l	0.0	0.0	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	54953	522
FHH/EurMcwi	concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	6			0.03	10E-7mol/l	0.01	0.02	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Dyets	56266	522
FHH/EurMcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	5			32.2	%	9.09	20.33	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56271	522
SS-Chr 16BN/Mcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	9			30.44	%	4.21	12.63	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56277	522
BN/NHsdMcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	6			54.5	%	9.09	22.26	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56296	522
SS-Chr 2BN/Mcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	15			34.6	%	4.62	17.89	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56293	522
FHH-Chr 12BN/Mcwi	sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	7			99.14	%	0.7	1.86	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56313	522
GH/OmrMcwi	sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	5			99.2	%	0.58	1.3	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56323	522
SS/JrHsdMcwi	heart wet weight	controlled sodium content diet (1 %) (for 14 days)	PhysGen General data	heart mass	male	70 days-84 days	47			1.13	g	0.02	0.14	digital scale post excision weight measurement				0					63226	529
SS-Cpt2m1Mcwi	body weight	controlled sodium content diet (1 %) (for 14 days)	PhysGen General data	body mass	male	70 days-84 days	7			312.57	g	2.61	6.9	whole body digital scale				0					63235	529
SS-Klf4m3Mcwi	heart right ventricle wet weight	controlled sodium content diet (1 %) (for 14 days)	PhysGen General data	heart right ventricle mass	male	70 days-84 days	9			0.21	g	0.01	0.02	digital scale post excision weight measurement				0					63249	529
SS-Hexim2em4Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		134.0	mmHg	1.0	1.41	radiotelemetry	carotid artery			0				-	43480	421
SS-Wdr72em2Mcwi+/+	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	7			126.17	mg/d	17.74	46.93	automated urine analysis				0				-	43509	421
SS-Hexim2em4Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			331.0	beats/min	9.0	12.73	radiotelemetry	carotid artery			0				-	43528	421
SS-Rasgrp3em1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	10			336.4	beats/min	12.53	39.62	radiotelemetry	carotid artery			0				-	43523	421
SS-Hexim2em4Mcwi+/+	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	3			10.16	mg/d	0.21	0.36	automated urine analysis				0				-	43560	421
SS-Wdr72em2Mcwi-/-	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	8			7.72	mEq/d	1.06	2.98	automated urine analysis				0				-	43568	421
SS-Wdr72em2Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	7			10.72	mEq/d	0.75	1.99	automated urine analysis				0				-	43573	421
SS-Hexim2em4Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	3			7.24	mEq/d	2.13	3.69	automated urine analysis				0				-	43576	421
SS-Wdr72em2Mcwi-/-	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	7			6.96	mg/d	1.24	3.28	automated urine analysis				0				-	43584	421
SS-Wdr72em2Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	8			1.31	g	0.03	0.08	post excision weight measurement				0				-	43600	421
FHH-Tgfbr2m2Mcwi	blood monocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	monocyte quantity	male	70 days-84 days	13			0.09	x 1000 cells/ul	0.02	0.07	automated blood cell counting method				0					61672	527
FHH-Htr1am1Mcwi	blood monocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	monocyte quantity	male	70 days-84 days	21			0.23	x 1000 cells/ul	0.03	0.16	automated blood cell counting method				0					61702	527
FHH-F10m2Mcwi	blood monocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	monocyte quantity	male	70 days-84 days	16			0.19	x 1000 cells/ul	0.04	0.14	automated blood cell counting method				0					61696	527
FHH-Nr4a1m1Mcwi	blood monocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	monocyte quantity	female	70 days-84 days	11			0.12	x 1000 cells/ul	0.03	0.11	automated blood cell counting method				0					61707	527
FHH/EurMcwi	blood monocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	monocyte quantity	female	70 days-84 days	25			0.2	x 1000 cells/ul	0.03	0.15	automated blood cell counting method				0					61713	527
F344-DccTn(sb-T2/Bart3)2.205Mcwi	blood monocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	monocyte quantity	male	70 days-84 days	6			0.12	x 1000 cells/ul	0.02	0.05	automated blood cell counting method				0					61721	527
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi	blood monocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	monocyte quantity	male	70 days-84 days	4			0.16	x 1000 cells/ul	0.02	0.03	automated blood cell counting method				0					61740	527
FHH-Ghsrm1Mcwi	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	kidney mass	female	70 days-84 days	10			0.95	g	0.02	0.07	digital scale post excision weight measurement				0					63378	529
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	kidney mass	female	70 days-84 days	2			0.57	g	0.01	0.01	digital scale post excision weight measurement				0					63397	529
FHH-Adra1am1Mcwi	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	kidney mass	female	70 days-84 days	9			0.91	g	0.02	0.05	digital scale post excision weight measurement				0					63394	529
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	kidney mass	female	70 days-84 days	2			0.61	g	0.0	0.0	digital scale post excision weight measurement				0					63400	529
FHH-Htr1am1Mcwi	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	heart mass	male	70 days-84 days	22			0.95	g	0.01	0.06	digital scale post excision weight measurement				0					63441	529
F344-Elmod3Tn(sb-T2/Bart3)2.42Mcwi	body length, nose to rump	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	male	70 days-84 days	7			23.64	cm	0.39	1.03	in vivo ruler method				0					63507	529
FHH-Adipoqm1Mcwi	body length, nose to rump	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	male	70 days-84 days	8			24.81	cm	0.28	0.8	in vivo ruler method				0					63518	529
FHH-Ccr2m1Mcwi	body length, nose to rump	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	female	70 days-84 days	7			21.71	cm	0.21	0.57	in vivo ruler method				0					63521	529
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi	body length, nose to rump	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	female	70 days-84 days	8			19.88	cm	0.21	0.58	in vivo ruler method				0					63532	529
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi	body length, nose to rump	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	male	70 days-84 days	1			21.0	cm			in vivo ruler method				0					63540	529
FHH-Slc8a2m1Mcwi	body length, nose to rump	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body length	male	70 days-84 days	15			24.2	cm	0.14	0.53	in vivo ruler method				0					63562	529
FHH-Lcatm1Mcwi	body weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen General data	body mass	female	70 days-84 days	15			180.2	g	4.47	17.32	whole body digital scale				0					63594	529
SS-Adra2aem1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	6			358.83	beats/min	9.8	24.0	radiotelemetry	carotid artery			0				-	43675	421
SS-Ulk3em4Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	15			379.53	beats/min	4.76	18.45	radiotelemetry	carotid artery			0				-	43683	421
SS-Ghsrm3Mcwi	serum potassium level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	male	70 days-84 days	2			3.55	mmol/l	0.15	0.21	flame atomic emission spectrometry				0					61751	527
SS-Klf4m3Mcwi	serum potassium level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood potassium amount	male	70 days-84 days	8			4.38	mmol/l	0.29	0.82	flame atomic emission spectrometry				0					61756	527
SS-Cpt2m1Mcwi	serum urea nitrogen level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood urea nitrogen amount	male	70 days-84 days	6			31.5	mg/dl	1.89	4.64	standard blood chemistry panel				0					61762	527
SS-Sod3m1Mcwi	serum urea nitrogen level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood urea nitrogen amount	male	70 days-84 days	10			25.5	mg/dl	1.81	5.72	standard blood chemistry panel				0					61764	527
SS-Cpt2m1Mcwi	serum urea nitrogen level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood urea nitrogen amount	female	70 days-84 days	1			44.0	mg/dl			standard blood chemistry panel				0					61767	527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi	serum sodium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	male	70 days-84 days	1			144.0	mmol/l			flame atomic emission spectrometry				0					61775	527
FHH-Agtr1bm1Mcwi	serum sodium level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood sodium amount	female	70 days-84 days	14			140.21	mmol/l	0.5	1.89	flame atomic emission spectrometry				0					61786	527
LE/BluGill	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	14			29.36	%	3.99	14.92	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	55006	522
SS-Chr 6BN/Mcwi	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	8			24.25	%	4.97	14.05	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	55080	522
FHH-Chr 6BN/Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	9			1.15	g/mg	0.15	0.45	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	57315	522
FHH-Chr 10BN/Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	10			0.93	g/mg	0.11	0.34	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	57342	522
FHH-Chr 8BN/Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	10			1.06	g/mg	0.13	0.42	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	57345	522
SS-Chr 20BN/Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	10			1.48	g/mg	0.05	0.15	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	57364	522
SS-Chr 13BN/Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	15			0.87	g/mg	0.1	0.38	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	57359	522
SS-Chr 11BN/Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	10			0.81	g/mg	0.07	0.21	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	57372	522
FHH-Chr YBN/Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	11			0.79	g/mg	0.08	0.26	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	57370	522
SS-Chr XBN/Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	10			1.27	g/mg	0.09	0.28	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	57375	522
FHH-Chr 12BN/Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	12			1.57	E-7mole	0.18	0.63	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56494	522
FHH-Chr 2BN/Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	9			1.57	E-7mole	0.17	0.5	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56514	522
SS-Chr 16BN/Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	11			2.8	E-7mole	1.24	4.11	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56541	522
SS-Chr 3BN/Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	9			1.53	E-7mole	0.22	0.66	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56544	522
FHH-Chr 13BN/Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	9			1.23	E-7mole	0.17	0.51	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms and pups used in studies were fed Teklad	56546	522
F344-DccTn(sb-T2/Bart3)2.205Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	7			-8.19	null	0.16	0.41	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		63104	528
FHH-Adra1am1Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	8			-7.78	null	0.12	0.34	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		63109	528
F344-Nrg1Tn(sb-T2/Bart3)2.183Mcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	5			-8.03	null	0.07	0.16	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		63120	528
BN/NHsdMcwi	logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	5			-8.13	null	0.03	0.07	wire myography using a Digi-Med tissue force analysis system with force transducer				0			EC50 value is moles/liter		63123	528
FHH-Ccr2m1Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	6			1.66	g/mg	0.13	0.32	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63145	528
FHH-Adra1am1Mcwi	maximum contractile force per wet weight of aorta	controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)	PhysGen Vascular data	vasoconstriction trait	male	70 days-84 days	8			1.33	g/mg	0.11	0.32	wire myography using a Digi-Med tissue force analysis system with force transducer				0					63178	528
SS-Cpt2m1Mcwi	body weight	controlled sodium content diet (1 %) (for 14 days)	PhysGen Vascular data	body mass	female	70 days-84 days	2			199.5	g	5.5	7.78	whole body digital scale				0					63200	528
SS-Ghsrm3Mcwi	concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)	controlled sodium content diet (1 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	1			2.56	E-7mole			wire myography using a Digi-Med tissue force analysis system with force transducer				0					63214	528
WKY/NCrl	concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)	PhysGen Vascular data	vasoconstriction trait	female	70 days-84 days	9			0.04	umol/l	0.01	0.02	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	57432	522
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi	blood lymphocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	lymphocyte quantity	male	70 days-84 days	7			4.1	x 1000 cells/ul	0.41	1.09	automated blood cell counting method				0					62090	527
FHH-Tlr4m1Mcwi	blood lymphocyte count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	lymphocyte quantity	male	70 days-84 days	7			3.55	x 1000 cells/ul	0.38	1.0	automated blood cell counting method				0					62106	527
BN-Tgfbr2m1Mcwi	serum total bilirubin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bilirubin amount	male	70 days-84 days	7			0.1	mg/dl	0.0	0.0	standard blood chemistry panel				0					62136	527
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi	serum total bilirubin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bilirubin amount	male	70 days-84 days	2			0.1	mg/dl	0.0	0.0	standard blood chemistry panel				0					62153	527
FHH-F10m2Mcwi	serum total bilirubin level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bilirubin amount	female	70 days-84 days	12			0.18	mg/dl	0.01	0.05	standard blood chemistry panel				0					62155	527
F344/NHsd	blood eosinophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	eosinophil quantity	male	70 days-84 days	7			0.03	x 1000 cells/ul	0.02	0.04	automated blood cell counting method				0					62227	527
F344-DccTn(sb-T2/Bart3)2.205Mcwi	blood eosinophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	eosinophil quantity	female	70 days-84 days	4			0.05	x 1000 cells/ul	0.02	0.05	automated blood cell counting method				0					62240	527
FHH-F10m1Mcwi	blood eosinophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	eosinophil quantity	male	70 days-84 days	10			0.06	x 1000 cells/ul	0.02	0.06	automated blood cell counting method				0					62238	527
FHH-Ghsrm1Mcwi	blood eosinophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	eosinophil quantity	female	70 days-84 days	9			0.08	x 1000 cells/ul	0.03	0.08	automated blood cell counting method				0					62243	527
BN-Lcatm3Mcwi	blood eosinophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	eosinophil quantity	female	70 days-84 days	2			0.17	x 1000 cells/ul	0.17	0.24	automated blood cell counting method				0					62246	527
SS-Wdr72em1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	1			342.0	beats/min			radiotelemetry	carotid artery			0				-	43721	441
SS-Plekha7em1Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	9			366.0	beats/min	7.74	23.21	radiotelemetry	carotid artery			0				-	43731	441
SS-Slc30a8em2Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	11			357.0	beats/min	5.64	18.7	radiotelemetry	carotid artery			0				-	43758	441
SS-Plcd3em7Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	9	1/3 systolic pressure + 2/3 diastolic pressure		142.78	mmHg	4.69	14.06	radiotelemetry	carotid artery			0				-	43801	441
SS-Plcd3em7Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	9	1/3 systolic pressure + 2/3 diastolic pressure		149.56	mmHg	5.16	15.48	radiotelemetry	carotid artery			0				-	43863	441
SS-Wdr72em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		130.0	mmHg	3.0	4.24	radiotelemetry	carotid artery			0				-	43871	441
SS-Cyp1a1em5Mcwi+/+	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	2			309.0	g	16.0	22.6	whole body digital scale				0				-	43895	441
SS-Cyp1a1em2Mcwi-/-	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	10			307.6	g	5.1	16.2	whole body digital scale				0				-	43892	441
SS-Nppaem4Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		142.5	mmHg	4.5	6.36	radiotelemetry	carotid artery			0				-	43884	441
SS-Cdh13em1Mcwi+/+	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	4			296.8	g	12.8	25.6	whole body digital scale				0				-	43900	441
SS-Ulk3em1Mcwi-/+	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	3			331.0	g	13.1	22.6	whole body digital scale				0				-	43903	441
SS-Tcf7l2em1Mcwi+/+	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	5			314.8	g	7.0	15.6	whole body digital scale				0				-	43905	441
SS-Wdr72em1Mcwi-/-	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	1			317.0	g			whole body digital scale				0				-	43908	441
SS-Cyp1a1em2Mcwi+/+	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	3			316.0	g	13.5	23.4	whole body digital scale				0				-	43911	441
F344/DuCrl	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	male	70 days-84 days	18			58.44	%	2.97	12.58	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56706	522
F344/DuCrl	hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	18			53.28	%	3.23	13.72	wire myography using a Digi-Med tissue force analysis system with force transducer				0				Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan	56711	522
SS.SR-(D13Mit9-D13Mit1)/Jr	systolic blood pressure	controlled sodium content diet (0.2 %) (for 10 days) then controlled sodium content diet (2 %) (between 41 and 44 days)	Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41	arterial blood pressure trait	male	81 days-84 days	20	data obtained at three consistent sessions per day	serial mean	208.0	mmHg			tail cuff plethysmography		345600		0					65973	650
SS-Nox4em2Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	5			1.35	g	0.05	0.12	post excision weight measurement				0				-	66244	717
SS-Ets1em1Mcwi-/+	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	10			1.28	g	0.07	0.22	post excision weight measurement				0				-	66247	717
F344-Elmod3Tn(sb-T2/Bart3)2.42Mcwi	hematocrit	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	male	70 days-84 days	5			46.36	%	0.45	1.01	automated blood cell counting method				0					60630	527
F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi	hematocrit	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	male	70 days-84 days	3			42.1	%	1.48	2.57	automated blood cell counting method				0					60646	527
FHH-Ccr2m1Mcwi	hematocrit	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	male	70 days-84 days	8			46.94	%	1.66	4.7	automated blood cell counting method				0					60652	527
F344-DccTn(sb-T2/Bart3)2.205Mcwi	hematocrit	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	female	70 days-84 days	4			45.23	%	0.86	1.72	automated blood cell counting method				0					60662	527
BN-Lcatm3Mcwi	hematocrit	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	female	70 days-84 days	2			44.5	%	0.4	0.57	automated blood cell counting method				0					60668	527
FHH-Adipoqm3Mcwi	hematocrit	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	female	70 days-84 days	6			42.88	%	0.61	1.49	automated blood cell counting method				0					60676	527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi	hematocrit	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte quantity	female	70 days-84 days	2			44.4	%	0.4	0.57	automated blood cell counting method				0					60687	527
SS-Cpt2m1Mcwi	serum alkaline phosphatase activity level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	female	70 days-84 days	1			41.0	U/l			standard blood chemistry panel				0					60701	527
SS/JrHsdMcwi	serum alkaline phosphatase activity level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alkaline phosphatase amount	female	70 days-84 days	17			56.53	U/l	2.15	8.85	standard blood chemistry panel				0					60703	527
SS/JrHsdMcwi	serum albumin level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood albumin amount	male	70 days-84 days	41			3.4	g/dl	0.06	0.37	standard blood chemistry panel				0					60717	527
SS-Klf4m3Mcwi	serum albumin level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood albumin amount	male	70 days-84 days	8			3.36	g/dl	0.11	0.31	standard blood chemistry panel				0					60720	527
SS-Sod3m1Mcwi	serum phosphate level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood phosphate amount	male	70 days-84 days	10			9.0	mg/dl	0.4	1.26	standard blood chemistry panel				0					60728	527
SS-Cpt2m1Mcwi	serum phosphate level	controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood phosphate amount	female	70 days-84 days	1			6.0	mg/dl			standard blood chemistry panel				0					60731	527
FHH-Adipoqm1Mcwi	mean corpuscular volume	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	erythrocyte size trait	female	70 days-84 days	9			54.91	fl	0.57	1.72	automated blood cell counting method				0					60736	527
FHH-Adipoqm1Mcwi	serum urea nitrogen level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood urea nitrogen amount	female	70 days-84 days	9			20.0	mg/dl	2.58	7.75	standard blood chemistry panel				0					60142	527
F344-DccTn(sb-T2/Bart3)2.205Mcwi	serum urea nitrogen level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood urea nitrogen amount	female	70 days-84 days	4			19.75	mg/dl	3.15	6.29	standard blood chemistry panel				0					60180	527
FHH-Ghsrm1Mcwi	serum urea nitrogen level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood urea nitrogen amount	male	70 days-84 days	15			17.07	mg/dl	0.49	1.91	standard blood chemistry panel				0					60191	527
BN-Lcatm3Mcwi	serum urea nitrogen level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood urea nitrogen amount	female	70 days-84 days	2			28.0	mg/dl	2.0	2.83	standard blood chemistry panel				0					60186	527
FHH-Tgfbr2m2Mcwi	serum alanine aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alanine transaminase amount	female	70 days-84 days	14			46.14	U/l	5.21	19.49	standard blood chemistry panel				0					61442	527
FHH-Lcatm1Mcwi	serum alanine aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alanine transaminase amount	female	70 days-84 days	15			45.27	U/l	8.34	32.3	standard blood chemistry panel				0					61445	527
BN-Tgfbr2m1Mcwi	serum alanine aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alanine transaminase amount	female	70 days-84 days	3			37.67	U/l	4.18	7.23	standard blood chemistry panel				0					61439	527
FHH-Ccr2m1Mcwi	serum alanine aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alanine transaminase amount	male	70 days-84 days	8			50.63	U/l	3.33	9.43	standard blood chemistry panel				0					61462	527
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi	serum alanine aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alanine transaminase amount	male	70 days-84 days	2			64.5	U/l	22.5	31.82	standard blood chemistry panel				0					61467	527
BN-Lcatm3Mcwi	serum alanine aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alanine transaminase amount	female	70 days-84 days	2			106.5	U/l	38.5	54.45	standard blood chemistry panel				0					61478	527
BN-Lcatm3Mcwi	serum alanine aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alanine transaminase amount	male	70 days-84 days	1			74.0	U/l			standard blood chemistry panel				0					61481	527
FHH-Adipoqm3Mcwi	serum alanine aminotransferase activity level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alanine transaminase amount	female	70 days-84 days	6			41.83	U/l	2.2	5.38	standard blood chemistry panel				0					61486	527
FHH-Tlr4m1Mcwi	serum alanine aminotransferase activity level	controlled sodium content diet (4 %) then fasting (for 16 hours)	PhysGen Biochemistry data	blood alanine transaminase amount	male	70 days-84 days	7			50.14	U/l	5.75	15.21	standard blood chemistry panel				0					61492	527
SS-Gpr183em3Mcwi-/-	right kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	8			1.61	g	0.07	0.19	post excision weight measurement				0				-	66257	717
SS-Nckap5em1Mcwi-/-	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	7			317.7	g	10.6	28.2	whole body digital scale				0				-	66276	717
FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi+/+	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	5			279.4	g	5.2	11.7	whole body digital scale				0				-	66265	717
SS-Cybaem1Mcwi-/-	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	6			297.2	g	8.7	21.2	whole body digital scale				0				-	66289	717
SS-Ulk4em3Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	4			396.5	beats/min	6.99	13.99	radiotelemetry	carotid artery			0				-	66332	717
SS-Acad10em2Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	12			360.67	beats/min	11.6	40.2	radiotelemetry	carotid artery			0				-	66334	717
SS-Tgfb1em3Mcwi+/-	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	3			336.67	beats/min	19.32	33.47	radiotelemetry	carotid artery			0				-	66337	717
WKY/Bbb	systolic blood pressure	controlled sodium content diet	Kreutz R, et al., Proc Natl Acad Sci U S A 1995 Sep 12;92(19):8778-82	arterial blood pressure trait	not specified	0 days	8			124.8	mmHg	1.1	3.1	radiotelemetry		0.0		0					67196	116
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco	heart wet weight	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 0 and 672 hours) then controlled sodium content diet (4 %) (between 46 and 48 days)	Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.	heart mass	male	114 days-118 days	6			1.78	g	0.05	0.12	post excision weight measurement		0		0					65131	283
SS.LEW-(D7Rat73-D7Rat128)/Ayd	mean arterial blood pressure	controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 49 days)	Crespo K, et al., J Hypertens. 2011 Mar;29(3):460-5.	arterial blood pressure trait	male	66 days-73 days	6			138.0	mmHg	3.0	7.35	intra-aortic abdominal radiotelemetry		0		0					65148	563
SS.SR-(D7Mco19-D7Mco7)/Jr	heart weight to body weight ratio	controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 0 and 672 hours) then controlled sodium content diet (4 %) (between 46 and 48 days)	Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.	heart mass	male	114 days-118 days	3			5.09	g/kg	0.4	0.69	post excision weight measurement		0		0					65136	283
FHH-Ghsrm1Mcwi	serum phosphate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood phosphate amount	female	70 days-84 days	9			7.63	mg/dl	0.3	0.9	standard blood chemistry panel				0					61567	527
BN-Lcatm3Mcwi	serum phosphate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood phosphate amount	male	70 days-84 days	1			6.7	mg/dl			standard blood chemistry panel				0					61573	527
BN-Lcatm3Mcwi	serum phosphate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood phosphate amount	female	70 days-84 days	2			6.85	mg/dl	0.25	0.35	standard blood chemistry panel				0					61570	527
FHH-Tgfbr2m2Mcwi	serum bicarbonate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bicarbonate amount	female	70 days-84 days	10			16.0	mmol/l	0.83	2.62	standard blood chemistry panel				0					61606	527
F344-Nrg1Tn(sb-T2/Bart3)2.183Mcwi	serum phosphate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood phosphate amount	male	70 days-84 days	5			7.58	mg/dl	0.35	0.79	standard blood chemistry panel				0					61595	527
FHH-Procm1Mcwi	serum bicarbonate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bicarbonate amount	male	70 days-84 days	10			13.3	mmol/l	1.37	4.35	standard blood chemistry panel				0					61628	527
FHH-Ghsrm1Mcwi	serum bicarbonate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bicarbonate amount	female	70 days-84 days	9			16.56	mmol/l	0.63	1.88	standard blood chemistry panel				0					61639	527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi	serum bicarbonate level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood bicarbonate amount	female	70 days-84 days	2			23.0	mmol/l	0.0	0.0	standard blood chemistry panel				0					61644	527
SS-Plekha7em4Mcwi-/-	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	13			309.6	g	6.8	24.6	whole body digital scale				0				-	43915	441
SS-Mstnem3Mcwi+/+	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	8			332.6	g	2.2	6.2	whole body digital scale				0				-	43924	441
SS-Aldh2em2Mcwi+/+	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	6			321.0	g	4.8	11.8	whole body digital scale				0				-	43927	441
SS-Tcf7l2em1Mcwi-/+	body weight	controlled sodium content diet (4 %) (for 10 days)	PhysGen Knockout data	body mass	male	70 days-77 days	2			339.5	g	7.5	10.6	whole body digital scale				0				-	43937	441
SS-Stk39em2Mcwi+/+	urine total protein excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	total urine protein amount	male	70 days-77 days	6			72.2	mg/d	11.68	28.62	automated urine analysis				0				-	43953	441
SS-Slc30a8em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	4			341.5	beats/min	14.87	29.74	radiotelemetry	carotid artery			0				-	44024	441
SS-Mstnem3Mcwi-/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	1			377.0	beats/min			radiotelemetry	carotid artery			0				-	44035	441
SS-Nppbem4Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	8			352.51	beats/min	9.93	28.1	radiotelemetry	carotid artery			0				-	44043	441
SS-Nppbem2Mcwi-/-	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	15			347.06	beats/min	5.71	22.11	radiotelemetry	carotid artery			0				-	44062	441
SS-Nppaem4Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			343.5	beats/min	9.5	13.44	radiotelemetry	carotid artery			0				-	44070	441
SS-Plcd3em4Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	3			333.33	beats/min	7.54	13.05	radiotelemetry	carotid artery			0				-	44072	441
SS-Kcnq1em14Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	7	1/3 systolic pressure + 2/3 diastolic pressure		132.43	mmHg	5.57	14.73	radiotelemetry	carotid artery			0				-	44078	441
SS-Cyp1a1em5Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		129.5	mmHg	6.5	9.19	radiotelemetry	carotid artery			0				-	44080	441
SS-Prokr1em2Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	7	1/3 systolic pressure + 2/3 diastolic pressure		139.29	mmHg	7.31	19.34	radiotelemetry	carotid artery			0				-	44102	441
SS-Aldh2em2Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	6	1/3 systolic pressure + 2/3 diastolic pressure		154.5	mmHg	11.34	27.78	radiotelemetry	carotid artery			0				-	44112	441
SS-Wdr72em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		130.5	mmHg	0.5	0.71	radiotelemetry	carotid artery			0				-	44118	441
SS-Ncf2em1Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	4			335.75	beats/min	14.86	29.73	radiotelemetry	carotid artery			0				-	66345	717
SS-Cybaem1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		140.5	mmHg	24.5	34.65	radiotelemetry	carotid artery			0				-	66433	717
SS-Renem1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 13 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	5	1/3 systolic pressure + 2/3 diastolic pressure		128.6	mmHg	7.0	15.65	radiotelemetry	carotid artery			0				-	66436	717
SS-Mthfrem1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	1	/3 systolic pressure + 2/3 diastolic pressure		151.0	mmHg			radiotelemetry	carotid artery			0				-	66455	717
SS-Ulk4em3Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	/3 systolic pressure + 2/3 diastolic pressure		174.25	mmHg	19.31	38.62	radiotelemetry	carotid artery			0				-	66452	717
SS-Gpr183em2Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	8	/3 systolic pressure + 2/3 diastolic pressure		151.5	mmHg	7.87	22.26	radiotelemetry	carotid artery			0				-	66460	717
SS-Nckap5em2Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	6	/3 systolic pressure + 2/3 diastolic pressure		146.0	mmHg	5.34	13.08	radiotelemetry	carotid artery			0				-	66463	717
SS/JrHsdMcwi	mean arterial blood pressure	controlled sodium content diet (0.4 %) (for 70 days) then controlled sodium content diet (8 %) (for 21 days)	Hoffman MJ, et al., Hypertension. 2013 Sep;62(3):557-63. doi: 10.1161/HYPERTENSIONAHA.113.01708. Epub 2013 Jul 1.	arterial blood pressure trait	male	91 days	12		serial mean	182.0	mmHg	6.0	20.78	intra-aortic abdominal radiotelemetry via femoral cannulation		10800.0		0					98699	2141
F344-DccTn(sb-T2/Bart3)2.205Mcwi	serum glucose level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood glucose amount	female	70 days-84 days	4			138.25	mg/dl	24.59	49.18	standard blood chemistry panel				0					62486	527
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi	serum glucose level	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	blood glucose amount	female	70 days-84 days	2			171.5	mg/dl	19.5	27.58	standard blood chemistry panel				0					62508	527
FHH-Adipoqm2Mcwi	acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel	controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)	PhysGen Vascular data	vasodilation trait	female	70 days-84 days	15			66.87	%	6.37	24.67	wire myography using a Digi-Med tissue force analysis system with force transducer				0					62590	528
SS-Klf4m3Mcwi	blood eosinophil count	controlled sodium content diet (1 %) (for 14 days) then fasting (between 16 and 1 hours)	PhysGen Biochemistry data	eosinophil quantity	male	70 days-84 days	8			0.1	x 1000 cells/ul	0.04	0.1	automated blood cell counting method				0					60822	527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi	blood neutrophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	neutrophil quantity	female	70 days-84 days	2			0.56	x 1000 cells/ul	0.07	0.09	automated blood cell counting method				0					60838	527
FHH-Lcatm1Mcwi	blood neutrophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	neutrophil quantity	male	70 days-84 days	13			0.96	x 1000 cells/ul	0.11	0.39	automated blood cell counting method				0					60832	527
FHH-Agtr1bm1Mcwi	blood neutrophil count	controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours)	PhysGen Biochemistry data	neutrophil quantity	male	70 days-84 days	15			1.21	x 1000 cells/ul	0.09	0.33	automated blood cell counting method				0					60835	527
SS/NEisSlc	body weight	controlled sodium content diet (8 %) (for 42 days) then 0.9% sodium chloride solution (0.3 ml) (for 42 days)	Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806.	body mass	male	91 days	12			347.6	g	6.85	23.73	body weighing method		0.0		0					100696	2519
SS/NEisSlc	kidney weight	controlled sodium content diet (0.3 %) (for 49 days) then controlled sodium content diet (8 %) (for 42 days) then cilazapril (10 mg/kg/d) (for 42 days)	Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806.	kidney mass	male	91 days	6			1.38	g	0.04	0.1	post excision weight measurement		0.0		0					100704	2519
SS-Renem1Mcwi-/-	timed urine volume	controlled sodium content diet (0.4 %) (for 35 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	urine output	male	56 days	8			22.19	ml/d	1.98	5.6	metabolic cage urine volume measurement method		0.0		0					98315	2038
SS-Renem1Mcwi+/-	urine sodium excretion rate	controlled sodium content diet (0.4 %) (for 35 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	urine sodium amount	male	56 days	9			0.81	mEq/d	0.08	0.24	urine sodium analysis		0.0		0					98326	2038
SS-Renem1Mcwi+/-	urine total protein excretion rate	controlled sodium content diet (0.4 %) (for 35 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	total urine protein amount	female	56 days	9			55.45	mg/d	5.64	16.92	urine total protein analysis		0.0		0					98323	2038
SS-Renem1Mcwi-/-	creatinine clearance to total kidney weight ratio	controlled sodium content diet (0.4 %) (for 42 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	glomerular filtration trait	female	63 days	4			0.3	ml/min/g	0.03	0.06	unspecified method		0.0		0					98354	2038
SS/Jr	heart rate	controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 28 days)	Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.	heart pumping trait	male	68 days-70 days	8		serial mean	397.0	beats/min	9.01	25.48	radiotelemetry		0.0		0					97979	1958
SS.BN-(D12Hmgc7-D12Hmgc6)/Mcwi	mean arterial blood pressure	controlled sodium content diet (1 %) (between 42 and 49 days)	Prisco SZ, et al., Hypertension. 2014 Jul 7. pii: HYPERTENSIONAHA.114.03550.	arterial blood pressure trait	male	71 days-77 days	6			110.0	mmHg	1.0	2.45	intra-aortic abdominal radiotelemetry		0.0		0					96806	1698
F344-Hsd11b2em1Jmul+/+	urine potassium level	controlled sodium content diet (0.3 %) then controlled sodium content diet (3 %) (between 7 and 10 days)	Mullins LJ, et al., Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15.	urine potassium amount	male	168 days	4			1794.3	mmol/l	174.4	348.8	urine potassium analysis		0.0		0					105029	3008
F344-Hsd11b2em1Jmul+/+	urine sodium level	controlled sodium content diet (0.3 %) then controlled sodium content diet (3 %) (between 7 and 10 days)	Mullins LJ, et al., Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15.	urine sodium amount	male	168 days	4			17145.0	mmol/l	2162.0	4324.0	urine sodium analysis		0.0		0					105023	3008
F344-Hsd11b2em1Jmul+/+	urine sodium level to urine potassium level ratio	controlled sodium content diet (0.3 %) then controlled sodium content diet (3 %) (between 7 and 10 days)	Mullins LJ, et al., Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15.	urine sodium amount	male	168 days	4			9.56	null	0.54	1.08	urine electrolyte analysis		0.0		0					105035	3008
SHR-Ndufc2em2Mcwi+/+	urine total protein excretion rate	controlled protein content diet (19.7 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) and controlled sodium content diet (3.7 mg/g) (for 56 days)	Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701.	total urine protein amount	not specified	98 days	12			47.0	mg/d	7.51	26.0	urine analysis		0.0		0					97940	1938
SS-Plekha7em4Mcwi-/-	renal cortex volume	controlled sodium content diet (8 %) (for 28 days)	Endres BT, et al., Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12817-22. doi: 10.1073/pnas.1410745111. Epub 2014 Aug 18.	kidney cortex morphology trait	male	91 days	10			406.0	mm3	85.0	268.79	ex vivo light microscopy with histochemistry and digital image analysis		0.0		0					105749	3022
SR/NEisSlc	percent change in mean arterial blood pressure	controlled sodium content diet (0.3 %) (for 28 days) then tempol (4 mol/l) (between 0 and 0 hours)	Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18.	arterial blood pressure trait	male	63 days-70 days	7			-14.1	%	3.2	8.47	vascular fluid filled catheter		0.0		0					102378	2687
SS.BN-(D13Hmgc1048-D13Hmgc1050)/Mcwi	systolic blood pressure	controlled sodium content diet (0.4 %) (between 23 and 32 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	arterial blood pressure trait	male	44 days-53 days	11		serial mean	122.0	mmHg	2.0	6.63	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		carotid a. to thoracic aorta implant	strain 26-P		98482	2079
SS.BN-(D13Got42-D13Hmgc497)/Mcwi	heart rate	controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days)	Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.	heart pumping trait	male	60 days-67 days	7		serial mean	372.0	beats/min	11.0	29.1	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		intra-carotid radiotelemetry	intra-carotid radiotelemetry		98615	2098
SS.BN-(D13Mit5-D13Rat32)/Mcwi	heart rate	controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days)	Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.	heart pumping trait	male	60 days-67 days	14		serial mean	399.0	beats/min	12.0	44.9	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		intra-carotid radiotelemetry	intra-carotid radiotelemetry		98618	2098
SR/NEisSlc	serum urea nitrogen level	controlled sodium content diet (0.3 %) (for 91 days)	Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806.	blood urea nitrogen amount	male	91 days	6			19.2	mg/dl	1.22	2.99	serum urea nitrogen analysis		0.0		0					100674	2519
SS/NEisSlc	serum creatinine level	controlled sodium content diet (8 %) (for 42 days) then 0.9% sodium chloride solution (0.3 ml) (for 42 days)	Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806.	blood creatinine amount	male	91 days	12			0.73	mg/dl	0.05	0.18	automated blood creatinine analysis		0.0		0					100677	2519
SS-Mthfrem1Mcwi-/+	heart rate	controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days)	Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4.	heart pumping trait	male	58 days-67 days	0		serial mean	330.0	beats/min	12.0		intra-aortic abdominal radiotelemetry		32400.0		0					98422	2059
SS-Mthfrem1Mcwi-/+	systolic blood pressure	controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days)	Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4.	arterial blood pressure trait	male	58 days-67 days	0		serial mean	152.0	mmHg	6.0		intra-aortic abdominal radiotelemetry		32400.0		0					98415	2059
SS	body weight	controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 84 days)	Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18.	body mass	male	126 days	6			323.0	g	5.72	14.0	body weighing method		0.0		0					103300	2803
SR	heart left ventricle end-systolic diameter	controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 84 days)	Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18.	heart left ventricle end-systolic diameter	male	126 days	6			4.9	mm	0.2	0.5	transthoracic echocardiography		0.0		0					103315	2803
SS/Jr	mean arterial blood pressure	controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)	Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.	arterial blood pressure trait	male	68 days-70 days	6		serial mean	175.0	mmHg	3.75	9.19	radiotelemetry		0.0		0					97991	1958
SS	conduction velocity	controlled sodium content diet (6 %) (between 56 and 70 days) then pentobarbital (50 mg/kg)	Kamei K, et al., Circ J. 2007 Mar;71(3):390-6.	heart electrical impulse conduction trait	male	98 days-132 days	7			50.0	cm/min	4.54	12.0	electrocardiography		0.0		0			conduction velocity		103391	2804
SR/Hsd	plasma osmolality	controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then Gnai2 antisense oligonucleotide (4.17 ug/d) (for 21 days)	Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13.	blood molecular composition trait	male	91 days-119 days	6			301.3	umol/g	4.4	10.78	osmometry		0.0		0					102240	2682
SS.BN-(D13Hmgc1048-D13Hmgc1045)/Mcwi	heart rate	controlled sodium content diet (0.4 %) (between 23 and 32 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	heart pumping trait	male	44 days-53 days	11		serial mean	395.0	beats/min	5.0	16.58	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		carotid a. to thoracic aorta implant	strain 26-O		98516	2079
SS.BN-(D13Hmgc1048-D13Hmgc1045)/Mcwi	heart rate	controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	heart pumping trait	male	58 days-67 days	11		serial mean	366.0	beats/min	6.0	19.9	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		carotid a. to thoracic aorta implant	strain 26-O		98523	2079
SS-Clcn6em2Mcwi	diastolic blood pressure	controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days)	Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4.	arterial blood pressure trait	male	58 days-67 days	0		serial mean	101.0	mmHg	1.0		intra-aortic abdominal radiotelemetry		32400.0		0					98407	2059
SS/JrHsdMcwi	systolic blood pressure	controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	arterial blood pressure trait	male	58 days-67 days	14		serial mean	185.0	mmHg	5.0	18.71	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		carotid a. to thoracic aorta implant			98500	2079
SS/JrHsdMcwi	diastolic blood pressure	controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	arterial blood pressure trait	male	58 days-67 days	14		serial mean	141.0	mmHg	4.0	14.97	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		carotid a. to thoracic aorta implant			98507	2079
SR/NEisSlc	body weight	controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days)	Ishikawa M, et al., Int Heart J. 2013;54(2):98-106.	body mass	male	126 days	8			449.0	g	6.0	16.97	body weighing method		0.0		0					102310	2684
SR/NEisSlc	heart left ventricle fractional shortening	controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days)	Ishikawa M, et al., Int Heart J. 2013;54(2):98-106.	heart left ventricle end-diastolic diameter	male	126 days	8			52.6	%	0.7	1.98	transthoracic echocardiography		0.0		0					102316	2684
SS.BN-(D13Hmgc885-D13Hmgc664)/Mcwi	urine albumin excretion rate	controlled sodium content diet (0.4 %) (between 20 and 29 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	urine albumin amount	male	41 days-50 days	10			4.1	mg/d	1.2	3.79	urine microalbumin analysis		86400.0		0			strain 26-R		98533	2079
SS-Renem1Mcwi+/+	heart rate	controlled sodium content diet (0.4 %) (between 66 and 69 days)	Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17.	heart pumping trait	female	66 days-69 days	7		serial mean	386.01	beats/min	5.71	15.11	intra-aortic abdominal radiotelemetry		32400.0		0					98394	2038
SS.BN-(D13Got42-D13Hmgc497)/Mcwi	systolic blood pressure	controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days)	Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.	arterial blood pressure trait	male	60 days-67 days	7		serial mean	150.0	mmHg	6.0	15.87	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		intra-carotid radiotelemetry	strain 26-E		98572	2098
SR/JrIpcv	plasma triglyceride level	controlled sodium content diet (0.3 %)	Hojn¿ S, et al., Physiol Res. 2005;54(2):201-6.	blood triglyceride amount	male	0 days	0			0.43	mmol/l	0.11		plasma triglyceride analysis		0.0		0					102401	2688
SS.BN-(D13Hmgc1048-D13Hmgc1050)/Mcwi	urine albumin excretion rate	controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days)	Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3.	urine albumin amount	male	59 days-68 days	11			161.0	mg/d	21.0	69.65	urine microalbumin analysis		86400.0		0			strain 26-P		98538	2079
WKY/NHsd	skin potassium level plus skin sodium level to skin water level ratio	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)	Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.	skin mineral amount	male	0 days	7			0.18	null	0.01	0.02	ex vivo analysis of atomic composition following dry ashing		0.0		0		ashed skin	skin na+k/h2o		99145	2238
WKY/NHsd	skin potassium level to skin water level ratio	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.	skin potassium amount	male	0 days	8			69.0	mmol/l	2.5	7.07	ex vivo analysis of atomic composition following dry ashing		0.0		0		ashed skin	skin k/h2o		99158	2238
WKY/NHsd	plasma potassium level	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days)	Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.	blood potassium amount	male	0 days	7			4.2	mmol/l	0.3	0.79	automated blood electrolyte analysis		0.0		0					99165	2238
WKY/NHsd	plasma chloride level	controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days)	Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20.	blood chloride amount	male	0 days	8			109.1	mmol/l	1.0	2.83	automated blood electrolyte analysis		0.0		0					99170	2238
SS/NEisSlc	serum potassium level	controlled sodium content diet (0.3 %) (for 91 days)	Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806.	blood potassium amount	male	91 days	6			7.65	mmol/l	0.29	0.71	automated serum potassium test		0.0		0					100658	2519
SS.BN-(D13Got42-D13Hmgc354)/Mcwi	systolic blood pressure	controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days)	Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8.	arterial blood pressure trait	male	60 days-67 days	16		serial mean	183.0	mmHg	6.0	24.0	intra-aortic thoracic radiotelemetry via carotid cannulation		10800.0		0		intra-carotid radiotelemetry	strain 26-D		98571	2098
SS/Jr	heart wet weight	controlled sodium content diet (2 %) (between 24 and 27 days)	Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23	heart mass	not specified	64 days-71 days	46			1.23	g	0.01	0.07	post excision weight measurement		0		0				4 rats per cage, 2 SR/Jr 2 LEW/NCrl	64743	222
SS/Jr	systolic blood pressure	controlled sodium content diet (2 %) (between 24 and 28 days)	Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.	arterial blood pressure trait	male	63 days-70 days	20			210.0	mmHg	3.3	14.76	tail cuff plethysmography		0		0			average of 4days		65479	611
SS.LEW-(D1Rat211-D1Rat18)/Mco	systolic blood pressure	controlled sodium content diet (2 %) (between 24 and 28 days)	Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.	arterial blood pressure trait	male	63 days-70 days	20			180.0	mmHg	2.8	12.52	tail cuff plethysmography		0		0			average of 4days		65488	611
SS.LEW-(D1Mco4-D1Rat18)/Mco	systolic blood pressure	controlled sodium content diet (2 %) (between 24 and 28 days)	Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.	arterial blood pressure trait	male	63 days-70 days	20			178.0	mmHg	2.3	10.29	tail cuff plethysmography		0		0			average of 4days		65489	611
BN/NHsdMcwi	mean arterial blood pressure	controlled sodium content diet (0.4 %) (for 28 days) then controlled sodium content diet (8 %) (for 30 days) and controlled exposure to ambient light (for 12 hours)	Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15.	arterial blood pressure trait	male	91 days-93 days	42		continuous mean	109.0	mmHg	3.0	19.44	vascular indwelling catheter method	femoral artery	259200.0		0		3 h per day	increase		66139	229
SS/JrHsdMcwi	absolute change in mean arterial blood pressure	furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then norepinephrine (3 ug/kg/min) (for 0.1 hours)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	arterial blood pressure trait	female	101 days-103 days	13		serial mean	39.0	mmHg	6.0	21.63	vascular indwelling catheter method	left femoral artery	0.0		0					67302	151
SHR	heart rate	controlled sodium content diet (1 %) (for 14 days)	Aneas I, et al., Physiol Genomics. 2009 Mar 3;37(1):52-7. Epub 2009 Jan 6.	heart pumping trait	male	87 days	24		continuous mean	380.0	beats/min	8.0	39.19	vascular indwelling catheter method	femoral artery	1800		0		pressure transducer (P23Dd; Stathan, Hato Rey, Puerto Rico), amplifier (GPA-4 model 2; Stemtech, Wood Dale, IL), 10-bit analog-to- digital converter (DataQ Instruments, Akron, OH)			65346	306
BN/NHsdMcwi	absolute change in mean arterial blood pressure	controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) then tactile electric shock exposure (2 %)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	arterial blood pressure trait	female	92 days-94 days	14		serial mean	16.0	mmHg	3.0	11.22	vascular indwelling catheter method	left femoral artery	0		0					66149	151
SS-Nox4em2Mcwi-/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			337.5	beats/min	6.5	9.19	radiotelemetry	carotid artery			0				-	66625	717
SS-Acad10em2Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	5			350.2	beats/min	7.34	16.41	radiotelemetry	carotid artery			0				-	66624	717
SS-Nckap5em3Mcwi+/+	heart rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart pumping trait	male	70 days-77 days	2			349.0	beats/min	3.0	4.24	radiotelemetry	carotid artery			0				-	66621	717
SS-Tfdp2em2Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		143.0	mmHg	3.0	4.24	radiotelemetry	carotid artery			0				-	66640	717
SS-Nckap5em1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	6	1/3 systolic pressure + 2/3 diastolic pressure		127.5	mmHg	5.37	13.16	radiotelemetry	carotid artery			0				-	66639	717
SS-Chr 5BN-Cyp4a2em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	3	1/3 systolic pressure + 2/3 diastolic pressure		115.0	mmHg	7.02	12.17	radiotelemetry	carotid artery			0				-	66649	717
SS-Apoeem8Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		136.0	mmHg	3.0	4.24	radiotelemetry	carotid artery			0				-	66664	717
SS-Alms1em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	1	1/3 systolic pressure + 2/3 diastolic pressure		134.0	mmHg			radiotelemetry	carotid artery			0				-	66667	717
SS-Bcas3em4Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	1	1/3 systolic pressure + 2/3 diastolic pressure		126.0	mmHg			radiotelemetry	carotid artery			0				-	66673	717
SS-Renem1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	6	1/3 systolic pressure + 2/3 diastolic pressure		121.5	mmHg	5.89	14.43	radiotelemetry	carotid artery			0				-	66679	717
FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi+/+	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	5			7.9	mg/d	0.52	1.17	automated urine analysis				0				-	66690	717
SS-Nox4em2Mcwi-/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 11 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		122.0	mmHg	1.0	1.41	radiotelemetry	carotid artery			0				-	66687	717
SS-Acad10em2Mcwi-/-	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	13			10.9	mg/d	0.23	0.83	automated urine analysis				0				-	66697	717
SS-Tgfb1em3Mcwi+/-	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	3			12.27	mg/d	0.06	0.1	automated urine analysis				0				-	66700	717
SS-Apoeem7Mcwi+/+	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	3			10.08	mg/d	0.43	0.74	automated urine analysis				0				-	66713	717
SS-Rag1em1Mcwi+/+	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	4			11.39	mg/d	1.35	2.7	automated urine analysis				0				-	66727	717
SS-Chr 5BN-Cyp4a2em1Mcwi-/+	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	3			10.23	mg/d	1.09	1.89	automated urine analysis				0				-	66729	717
FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi-/-	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	2			8.94	mg/d	1.17	1.65	automated urine analysis				0				-	66738	717
SS-Mas1em1Mcwi+/+	urine creatinine excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine creatinine amount	male	70 days-77 days	2			12.28	mg/d	1.63	2.31	automated urine analysis				0				-	66746	717
FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi+/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	5			1.14	g	0.03	0.07	post excision weight measurement				0				-	66751	717
SS-Tgfb1em3Mcwi+/-	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	3			1.5	g	0.07	0.13	post excision weight measurement				0				-	66761	717
SS-Ncf2em1Mcwi+/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	5			1.44	g	0.03	0.07	post excision weight measurement				0				-	66769	717
SS-Gpr183em2Mcwi-/-	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	9			1.54	g	0.05	0.14	post excision weight measurement				0				-	66764	717
SS-Mmp2em1Mcwi+/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	1			1.38	g			post excision weight measurement				0				-	66777	717
SS-Cybaem1Mcwi-/-	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	6			1.34	g	0.03	0.06	post excision weight measurement				0				-	66775	717
SS-Apoeem7Mcwi+/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	3			1.44	g	0.04	0.06	post excision weight measurement				0				-	66774	717
SS-Rag1em1Mcwi+/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	4			1.53	g	0.07	0.13	post excision weight measurement				0				-	66788	717
SS-Mthfrem1Mcwi-/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	8			1.61	g	0.08	0.23	post excision weight measurement				0				-	66807	717
SS-Nox4em2Mcwi-/+	left kidney wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	kidney mass	male	70 days-77 days	2			1.25	g	0.03	0.04	post excision weight measurement				0				-	66810	717
SS-Ulk4em3Mcwi-/-	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	4			8.48	mEq/d	1.31	2.63	automated urine analysis				0				-	66818	717
SS-Acad10em2Mcwi-/-	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	13			9.57	mEq/d	1.12	4.05	automated urine analysis				0				-	66820	717
SS-Gpr183em2Mcwi-/-	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	9			8.82	mEq/d	1.43	4.28	automated urine analysis				0				-	66826	717
SS-Tfdp2em2Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	3			13.38	mEq/d	1.65	2.86	automated urine analysis				0				-	66825	717
SS.LEW-(D1Mco102-D1Mco129)/2Mco	systolic blood pressure	controlled sodium content diet (0.4 %) (between 36 and 40 days)	Joe B, et al., Hum Mol Genet. 2009 Aug 1;18(15):2825-38. Epub 2009 May 7.	arterial blood pressure trait	male	66 days-70 days	20		serial mean	176.0	mmHg	2.2	9.84	tail cuff plethysmography		345600		0		Rats warmed to 28 degrees C for measurement.			65311	565
SS/JrHsdMcwi	mean arterial blood pressure	controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg)	Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57.	arterial blood pressure trait	female	92 days-94 days	12		serial mean	142.0	mmHg	5.0	17.32	vascular indwelling catheter method	left femoral artery	0		0					65467	151
SS/JrRkb	single kidney wet weight to body weight ratio	controlled sodium content diet (0.2 %) (for 56 days)	Wendt N, et al., J Hypertens. 2007 Jan;25(1):95-102.	kidney mass	male	98 days	14			3.5	g/kg	0.05	0.19	post excision weight measurement		0		0					66086	669
SS-Chr 19SHR/Rkb	single kidney wet weight to body weight ratio	controlled sodium content diet (4 %) (for 56 days)	Wendt N, et al., J Hypertens. 2007 Jan;25(1):95-102.	kidney mass	male	98 days	20			4.0	g/kg	0.14	0.63	post excision weight measurement		0		0					66089	669
SS/JrRkb	heart right ventricle weight to body weight ratio	controlled sodium content diet (0.2 %) (for 56 days)	Wendt N, et al., J Hypertens. 2007 Jan;25(1):95-102.	heart right ventricle mass	male	98 days	14			0.52	mg/g	0.02	0.07	post excision weight measurement		0		0					66090	669
SS-Chr 19SHR/Rkb	heart right ventricle weight to body weight ratio	controlled sodium content diet (0.2 %) (for 56 days)	Wendt N, et al., J Hypertens. 2007 Jan;25(1):95-102.	heart right ventricle mass	male	98 days	20			0.51	mg/g	0.01	0.04	post excision weight measurement		0		0					66092	669
FHH-Chr 1BN-Sorcs1em1Mcwi-/-	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	12			6.21	mEq/d	0.8	2.78	automated urine analysis				0				-	66832	717
SS-Nckap5em1Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	5			11.54	mEq/d	1.15	2.58	automated urine analysis				0				-	66842	717
SS-Alms1em1Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	1			6.26	mEq/d			automated urine analysis				0				-	66851	717
SS-Ets1em1Mcwi+/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	4			7.37	mEq/d	0.72	1.44	automated urine analysis				0				-	66840	717
SS-Ets1em1Mcwi-/+	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	10			10.15	mEq/d	0.95	3.0	automated urine analysis				0				-	66856	717
SS-Renem1Mcwi-/-	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	5			7.06	mEq/d	1.41	3.15	automated urine analysis				0				-	66863	717
SS-Nckap5em3Mcwi-/-	urine sodium excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine sodium amount	male	70 days-77 days	3			11.79	mEq/d	0.69	1.2	automated urine analysis				0				-	66864	717
SS-Mthfrem1Mcwi+/+	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	1			17.0	mg/d			automated urine analysis				0				-	66882	717
SS-Gpr183em2Mcwi+/+	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	2			60.18	mg/d	6.81	9.62	automated urine analysis				0				-	66891	717
FHH-Chr 1BN-Sorcs1em1Mcwi+/+	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	3			2.18	mg/d	0.68	1.17	automated urine analysis				0				-	66883	717
SS-Chr 5BN-Cyp4a2em1Mcwi+/+	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	3			85.45	mg/d	5.57	9.64	automated urine analysis				0				-	66895	717
SS-Apoeem8Mcwi+/+	urine albumin excretion rate	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	urine albumin amount	male	70 days-77 days	2			27.98	mg/d	4.63	6.55	automated urine analysis				0				-	66909	717
SS.SHR-(D13Rat63-D13Mit1)/Mco	blood uric acid level	controlled sodium content diet (0.3 %)	Packard M, et al., Am J Physiol Renal Physiol. 2009 Apr;296(4):F839-46. Epub 2009 Jan 28.	blood uric acid amount	male	84 days	8			2.4	mg/dl	0.12	0.34	automated blood analysis		0		0					65786	246
SHR.SS-(D8Uia1-D8Rat90)/Mco	blood uric acid level	controlled sodium content diet (0.3 %)	Packard M, et al., Am J Physiol Renal Physiol. 2009 Apr;296(4):F839-46. Epub 2009 Jan 28.	blood uric acid amount	male	84 days	8			3.4	mg/dl	0.29	0.82	automated blood analysis		0		0					65788	246
SS-Alms1em1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	5	1/3 systolic pressure + 2/3 diastolic pressure		151.2	mmHg	7.61	17.02	radiotelemetry	carotid artery			0				-	66937	717
SS-Gpr183em1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	6	1/3 systolic pressure + 2/3 diastolic pressure		146.83	mmHg	9.12	22.34	radiotelemetry	carotid artery			0				-	66939	717
SS-Tfdp2em2Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		142.0	mmHg	2.0	2.83	radiotelemetry	carotid artery			0				-	66947	717
SS-Ets1em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	3	1/3 systolic pressure + 2/3 diastolic pressure		162.33	mmHg	13.2	22.85	radiotelemetry	carotid artery			0				-	66961	717
SS-Nckap5em1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	5	1/3 systolic pressure + 2/3 diastolic pressure		147.6	mmHg	11.82	26.43	radiotelemetry	carotid artery			0				-	66963	717
SS-Rag1em2Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	6	1/3 systolic pressure + 2/3 diastolic pressure		120.83	mmHg	4.57	11.2	radiotelemetry	carotid artery			0				-	66966	717
SS-Renem1Mcwi+/+	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	4	1/3 systolic pressure + 2/3 diastolic pressure		156.5	mmHg	17.87	35.74	radiotelemetry	carotid artery			0				-	66976	717
SS-Tfdp2em2Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	3	1/3 systolic pressure + 2/3 diastolic pressure		142.0	mmHg	12.58	21.79	radiotelemetry	carotid artery			0				-	66980	717
FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi-/-	mean arterial blood pressure	controlled sodium content diet (4 %) (for 12 days)	PhysGen Knockout data	arterial blood pressure trait	male	70 days-77 days	2	1/3 systolic pressure + 2/3 diastolic pressure		129.5	mmHg	4.5	6.36	radiotelemetry	carotid artery			0				-	66982	717
SS-Ube2q2em3Mcwi+/+	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	1			1.41	g			post excision weight measurement				0				-	67001	717
SS-Ets1em1Mcwi+/+	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	4			1.11	g	0.03	0.06	post excision weight measurement				0				-	67022	717
SS-Nox4em2Mcwi-/-	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	5			1.0	g	0.03	0.06	post excision weight measurement				0				-	67036	717
SS-Apoeem8Mcwi+/+	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	2			1.19	g	0.0	0.0	post excision weight measurement				0				-	67031	717
SS-Alms1em1Mcwi+/+	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male	70 days-77 days	1			1.16	g			post excision weight measurement				0				-	67034	717
SS-Rag1em2Mcwi+/+	heart wet weight	controlled sodium content diet (4 %) (for 14 days)	PhysGen Knockout data	heart mass	male

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Create Name:

Description:

Send us a Message

Phenominer Database Results (10000 results)