Phenominer Database Results (92 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Average Type Value Units SEM SD Method Method Duration Post Insult Time Value Clinical Measurement Notes Record ID Study ID
SR/NEisSlc serum urea nitrogen level controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. blood urea nitrogen amount male 126 days 8 16.3 mg/dl 0.9 2.55 serum urea nitrogen analysis 0.0 0 102328 2684
SR/NEisSlc time constant of left ventricular pressure decay controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 77 days 10 107.0 ms 0.79 2.5 volume pressure recording 0.0 0 102536 2690
SR/NEisSlc single kidney wet weight to body weight ratio controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney mass male 77 days 19 3.85 g/kg 0.06 0.28 post excision weight measurement 0.0 0 102462 2689
SR/NEisSlc body weight controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. body mass male 77 days 10 356.0 g 3.48 11.0 body weighing method 0.0 0 102480 2690
SR/NEisSlc body weight controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. body mass male 63 days 7 286.0 g 6.05 16.0 body weighing method 0.0 0 102405 2689
SR/NEisSlc urine total protein excretion rate to body weight ratio controlled sodium chloride content diet (8 %) (for 7 days) then 0.9% sodium chloride solution (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. total urine protein amount male 63 days 19 3.4 mg/d/100 g 0.25 1.1 urine protein analysis 0.0 0 102471 2689
SR/NEisSlc heart weight controlled sodium content diet (0.3 %) (for 91 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. heart mass male 91 days 6 1.23 g 0.05 0.12 post excision weight measurement 0.0 0 100708 2519
SR/NEisSlc serum potassium level controlled sodium content diet (0.3 %) (for 91 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. blood potassium amount male 91 days 6 7.5 mmol/l 0.33 0.81 automated serum potassium test 0.0 0 100659 2519
SR/NEisSlc urine aldosterone excretion rate controlled sodium content diet (0.3 %) (for 49 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. urine aldosterone amount male 49 days 6 15.37 ng/d 1.03 2.52 radioimmunoassay 0.0 0 ng/d 100694 2519
SR/NEisSlc ratio of change in renal sympathetic nerve activity controlled sodium content diet (8 %) (for 28 days) then tempol (4 mol/l) (between 0 and 0 hours) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. kidney sympathetic nerve activity male 63 days-70 days 6 -6.7 % 2.5 6.12 implanted wire electrode recording method 0.0 0 102375 2687
SR/NEisSlc serum creatinine level controlled sodium content diet (0.3 %) (for 91 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. blood creatinine amount male 91 days 6 0.57 mg/dl 0.05 0.12 automated blood creatinine analysis 0.0 0 100679 2519
SR/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 70 days 8 mean of 3 samples of undefined duration serial mean 124.0 mmHg 3.18 9.0 tail cuff plethysmography 0.0 0 102431 2689
SR/NEisSlc body weight controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. body mass male 126 days 8 449.0 g 6.0 16.97 body weighing method 0.0 0 102310 2684
SR/NEisSlc creatinine clearance controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. glomerular filtration trait male 126 days 8 3.9 ml/min 0.8 2.26 serum creatinine analysis 0.0 0 102331 2684
SR/NEisSlc urine total protein excretion rate controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. total urine protein amount male 126 days 8 38.0 mg/d 6.0 16.97 urine protein analysis 0.0 0 102337 2684
SR/NEisSlc end-systolic volume controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 77 days 10 0.07 ml 0.02 0.06 volume pressure recording 0.0 0 102512 2690
SR/NEisSlc serum uric acid level controlled sodium content diet (0.3 %) (for 91 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. blood uric acid amount male 91 days 6 0.02 umol/l 0.0 0.0 automated blood analysis 0.0 0 100684 2519
SR/NEisSlc kidney medullary adrenomedullin level controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney adrenomedullin amount male 77 days 7 0.34 fmol/mg 0.01 0.02 radioimmunoassay 0.0 0 102451 2689
SR/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 77 days 19 mean of 3 samples of undefined duration serial mean 128.0 mmHg 1.38 6.0 tail cuff plethysmography 0.0 0 102465 2689
SR/NEisSlc body weight controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. body mass male 126 days 10 483.0 g 5.69 18.0 body weighing method 0.0 0 102481 2690
SR/NEisSlc heart left ventricle weight controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricle mass male 126 days 10 0.94 g 0.0 0.0 post excision weight measurement 0.0 0 102485 2690
SR/NEisSlc heart left ventricle weight to body weight ratio controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricle mass male 77 days 10 2.33 mg/g 0.03 0.09 post excision weight measurement 0.0 0 102488 2690
SR/NEisSlc left ventricular end-diastolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 77 days 10 2.2 mmHg 0.6 1.9 volume pressure recording 0.0 0 102508 2690
SR/NEisSlc body weight controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. body mass male 70 days 8 309.0 g 3.89 11.0 body weighing method 0.0 0 102407 2689
SR/NEisSlc body weight controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. body mass male 77 days 7 371.0 g 4.54 12.0 body weighing method 0.0 0 102409 2689
SR/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 63 days 7 389.0 beats/min 9.07 24.0 tail cuff plethysmography 0.0 0 102411 2689
SR/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 63 days 7 mean of 3 samples of undefined duration serial mean 119.0 mmHg 3.02 8.0 tail cuff plethysmography 0.0 0 102429 2689
SR/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 77 days 7 mean of 3 samples of undefined duration serial mean 125.0 mmHg 3.02 8.0 tail cuff plethysmography 0.0 0 102433 2689
SR/NEisSlc kidney medullary adrenomedullin level controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney adrenomedullin amount male 70 days 8 0.34 fmol/mg 0.01 0.04 radioimmunoassay 0.0 0 102449 2689
SR/NEisSlc urine aldosterone excretion rate controlled sodium content diet (0.3 %) (for 84 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. urine aldosterone amount male 84 days 6 39.87 ng/d 11.4 27.92 radioimmunoassay 0.0 0 ng/d 100695 2519
SR/NEisSlc heart rate controlled sodium content diet (0.3 %) (for 28 days) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. heart pumping trait male 63 days-70 days 7 346.0 beats/min 13.0 34.39 vascular fluid filled catheter 0.0 0 102370 2687
SR/NEisSlc percent change in mean arterial blood pressure controlled sodium content diet (0.3 %) (for 28 days) then tempol (4 mol/l) (between 0 and 0 hours) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. arterial blood pressure trait male 63 days-70 days 7 -14.1 % 3.2 8.47 vascular fluid filled catheter 0.0 0 102378 2687
SR/NEisSlc systolic blood pressure controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. arterial blood pressure trait male 126 days 8 undefined 138.0 mmHg 5.0 14.14 tail cuff plethysmography 0.0 0 102313 2684
SR/NEisSlc mean arterial blood pressure controlled sodium content diet (0.3 %) (for 28 days) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. arterial blood pressure trait male 63 days-70 days 7 103.0 mmHg 3.0 7.94 vascular fluid filled catheter 0.0 0 102366 2687
SR/NEisSlc ratio of change in renal sympathetic nerve activity controlled sodium content diet (0.3 %) (for 28 days) then tempol (4 mol/l) (between 0 and 0 hours) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. kidney sympathetic nerve activity male 63 days-70 days 7 -8.0 % 0.7 1.85 implanted wire electrode recording method 0.0 0 102374 2687
SR/NEisSlc percent change in mean arterial blood pressure controlled sodium content diet (8 %) (for 28 days) then tempol (4 mol/l) (between 0 and 0 hours) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. arterial blood pressure trait male 63 days-70 days 6 -9.6 % 1.7 4.16 vascular fluid filled catheter 0.0 0 102379 2687
SR/NEisSlc serum creatinine level controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. blood creatinine amount male 126 days 8 0.22 mg/dl 0.01 0.03 serum creatinine analysis 0.0 0 102325 2684
SR/NEisSlc heart left ventricle plus septum weight to body weight ratio controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart left ventricle mass male 77 days 19 1.9 mg/g 0.03 0.13 post excision weight measurement 0.0 0 heart left ventricle plus septum weight to body weight ratio (CMO:0003869) 102459 2689
SR/NEisSlc heart left ventricle weight controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricle mass male 77 days 10 0.83 g 0.0 0.0 post excision weight measurement 0.0 0 102484 2690
SR/NEisSlc systolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. arterial blood pressure trait male 77 days 10 undefined 140.0 mmHg 2.21 7.0 tail cuff plethysmography 0.0 0 102492 2690
SR/NEisSlc left ventricular systolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 77 days 10 105.0 mmHg 5.38 17.0 volume pressure recording 0.0 0 102500 2690
SR/NEisSlc end-diastolic volume controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 77 days 10 0.13 ml 0.02 0.07 volume pressure recording 0.0 0 102516 2690
SR/NEisSlc end-diastolic volume controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 126 days 10 0.19 ml 0.02 0.07 volume pressure recording 0.0 0 102517 2690
SR/NEisSlc heart left ventricle end-systolic elastance controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 77 days 10 2404.0 mmHg/ml 78.42 248.0 volume pressure recording 0.0 0 102520 2690
SR/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 63 days 7 2.1 mEq/d 0.38 1.0 automated urine sodium analysis 0.0 0 102435 2689
SR/NEisSlc kidney cortical adrenomedullin level controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney adrenomedullin amount male 77 days 7 0.55 fmol/mg 0.02 0.06 radioimmunoassay 0.0 0 102445 2689
SR/NEisSlc urine total protein excretion rate to body weight ratio controlled sodium chloride content diet (8 %) (for 14 days) then 0.9% sodium chloride solution (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. total urine protein amount male 70 days 19 3.2 mg/d/100 g 0.21 0.9 urine protein analysis 0.0 0 102474 2689
SR/NEisSlc single kidney wet weight to body weight ratio controlled sodium content diet (0.3 %) (for 91 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. kidney mass male 91 days 6 3.61 g/kg 0.04 0.1 post excision weight measurement 0.0 0 100713 2519
SR/NEisSlc heart left ventricle plus septum weight to body weight ratio controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart left ventricle mass male 70 days 8 2.22 mg/g 0.06 0.16 post excision weight measurement 0.0 0 heart left ventricle plus septum weight to body weight ratio (CMO:0003869) 102419 2689
SR/NEisSlc single kidney wet weight to body weight ratio controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney mass male 70 days 8 4.09 g/kg 0.05 0.13 post excision weight measurement 0.0 0 102425 2689
SR/NEisSlc heart left ventricle fractional shortening controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. heart left ventricle end-diastolic diameter male 126 days 8 52.6 % 0.7 1.98 transthoracic echocardiography 0.0 0 102316 2684
SR/NEisSlc both kidneys wet weight to body weight ratio controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. kidney mass male 126 days 8 3.53 g/kg 0.04 0.11 post excision weight measurement 0.0 0 102322 2684
SR/NEisSlc timed urine volume controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. urine output male 126 days 8 30.4 ml/d 6.8 19.23 urine volume measurement method 0.0 0 102334 2684
SR/NEisSlc heart left ventricle diastolic volume-axis intercept controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 126 days 10 0.09 ml 0.02 0.06 volume pressure recording 0.0 0 102533 2690
SR/NEisSlc body weight controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. body mass male 77 days 19 370.0 g 2.52 11.0 body weighing method 0.0 0 102453 2689
SR/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 77 days 19 347.0 beats/min 7.34 32.0 tail cuff plethysmography 0.0 0 102456 2689
SR/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 77 days 19 2.2 mEq/d 0.16 0.7 automated urine sodium analysis 0.0 0 102468 2689
SR/NEisSlc heart left ventricle weight to body weight ratio controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricle mass male 126 days 10 1.95 mg/g 0.03 0.09 post excision weight measurement 0.0 0 102489 2690
SR/NEisSlc systolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. arterial blood pressure trait male 126 days 10 undefined 135.0 mmHg 2.21 7.0 tail cuff plethysmography 0.0 0 102493 2690
SR/NEisSlc heart rate controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart pumping trait male 77 days 10 464.0 beats/min 8.54 27.0 tail cuff plethysmography 0.0 0 102496 2690
SR/NEisSlc heart rate controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart pumping trait male 77 days 10 383.0 beats/min 6.96 22.0 tail cuff plethysmography 0.0 0 102504 2690
SR/NEisSlc end-systolic volume controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 126 days 10 0.09 ml 0.02 0.06 volume pressure recording 0.0 0 102513 2690
SR/NEisSlc heart left ventricle systolic volume-axis intercept controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 77 days 10 0.17 ml 0.02 0.06 volume pressure recording 0.0 0 102524 2690
SR/NEisSlc heart left ventricle systolic volume-axis intercept controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 126 days 10 0.39 ml 0.03 0.09 volume pressure recording 0.0 0 102525 2690
SR/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 70 days 8 396.0 beats/min 12.73 36.0 tail cuff plethysmography 0.0 0 102413 2689
SR/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 77 days 7 377.0 beats/min 8.32 22.0 tail cuff plethysmography 0.0 0 102415 2689
SR/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 70 days 8 1.9 mEq/d 0.21 0.6 automated urine sodium analysis 0.0 0 102437 2689
SR/NEisSlc kidney cortical adrenomedullin level controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney adrenomedullin amount male 63 days 7 0.59 fmol/mg 0.04 0.1 radioimmunoassay 0.0 0 102441 2689
SR/NEisSlc kidney cortical adrenomedullin level controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney adrenomedullin amount male 70 days 8 0.56 fmol/mg 0.02 0.06 radioimmunoassay 0.0 0 102443 2689
SR/NEisSlc kidney medullary adrenomedullin level controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney adrenomedullin amount male 63 days 7 0.31 fmol/mg 0.02 0.06 radioimmunoassay 0.0 0 102447 2689
SR/NEisSlc plasma renin activity level controlled sodium content diet (0.3 %) (for 91 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. renin activity male 91 days 6 3.23 ng/ml/h 0.45 1.11 radioimmunoassay 0.0 0 100689 2519
SR/NEisSlc body weight controlled sodium content diet (0.3 %) (for 91 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. body mass male 91 days 6 405.0 g 17.8 43.6 body weighing method 0.0 0 100698 2519
SR/NEisSlc kidney weight controlled sodium content diet (0.3 %) (for 91 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. kidney mass male 91 days 6 1.43 g 0.04 0.09 post excision weight measurement 0.0 0 100703 2519
SR/NEisSlc mean arterial blood pressure controlled sodium content diet (8 %) (for 28 days) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. arterial blood pressure trait male 63 days-70 days 6 100.0 mmHg 1.0 2.45 vascular fluid filled catheter 0.0 0 102367 2687
SR/NEisSlc percent change in heart rate controlled sodium content diet (8 %) (for 28 days) then tempol (4 mol/l) (between 0 and 0 hours) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. heart pumping trait male 63 days-70 days 6 -3.0 % 1.9 4.65 vascular fluid filled catheter 0.0 0 102383 2687
SR/NEisSlc serum total protein level controlled sodium content diet (0.3 %) (for 91 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. blood total protein amount male 91 days 6 4.85 g/dl 0.22 0.54 serum total protein analysis 0.0 0 100669 2519
SR/NEisSlc serum urea nitrogen level controlled sodium content diet (0.3 %) (for 91 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. blood urea nitrogen amount male 91 days 6 19.2 mg/dl 1.22 2.99 serum urea nitrogen analysis 0.0 0 100674 2519
SR/NEisSlc number of nucleated cells per kidney glomerulus controlled sodium content diet (0.3 %) (for 91 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. kidney glomerulus morphology trait male 91 days 6 33.0 null 0.75 1.84 ex vivo light microscopy with histochemistry 0.0 0 100728 2519
SR/NEisSlc heart left ventricle end-diastolic diameter controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. heart left ventricle end-diastolic diameter male 126 days 8 6.5 mm 0.1 0.28 transthoracic echocardiography 0.0 0 102319 2684
SR/NEisSlc heart rate controlled sodium content diet (8 %) (for 28 days) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. heart pumping trait male 63 days-70 days 6 342.0 beats/min 11.0 26.94 vascular fluid filled catheter 0.0 0 102371 2687
SR/NEisSlc percent change in heart rate controlled sodium content diet (0.3 %) (for 28 days) then tempol (4 mol/l) (between 0 and 0 hours) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. heart pumping trait male 63 days-70 days 7 -6.0 % 3.1 8.2 vascular fluid filled catheter 0.0 0 102382 2687
SR/NEisSlc heart left ventricle end-diastolic elastance controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart left ventricular blood pressure trait male 77 days 10 32.0 mmHg/ml 5.69 18.0 volume pressure recording 0.0 0 102528 2690
SR/NEisSlc heart left ventricle diastolic volume-axis intercept controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. cardiac output trait male 77 days 10 0.08 ml 0.02 0.07 volume pressure recording 0.0 0 102532 2690
SR/NEisSlc serum chloride level controlled sodium content diet (0.3 %) (for 91 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. blood chloride amount male 91 days 6 105.0 mmol/l 4.57 11.19 automated serum chloride test 0.0 0 100664 2519
SR/NEisSlc heart left ventricle plus septum weight to body weight ratio controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart left ventricle mass male 63 days 7 2.06 mg/g 0.06 0.15 post excision weight measurement 0.0 0 heart left ventricle plus septum weight to body weight ratio (CMO:0003869) 102417 2689
SR/NEisSlc heart left ventricle plus septum weight to body weight ratio controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart left ventricle mass male 77 days 7 1.97 mg/g 0.04 0.11 post excision weight measurement 0.0 0 heart left ventricle plus septum weight to body weight ratio (CMO:0003869) 102421 2689
SR/NEisSlc single kidney wet weight to body weight ratio controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney mass male 63 days 7 3.69 g/kg 0.1 0.26 post excision weight measurement 0.0 0 102423 2689
SR/NEisSlc single kidney wet weight to body weight ratio controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. kidney mass male 77 days 7 3.67 g/kg 0.05 0.13 post excision weight measurement 0.0 0 102427 2689
SR/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 77 days 7 2.7 mEq/d 0.49 1.3 automated urine sodium analysis 0.0 0 102439 2689
SR/NEisSlc serum sodium level controlled sodium content diet (0.3 %) (for 91 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. blood sodium amount male 91 days 6 138.0 mmol/l 5.76 14.11 automated serum sodium test 0.0 0 100653 2519
SR/NEisSlc heart weight to body weight ratio controlled sodium content diet (0.3 %) (for 91 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. heart mass male 91 days 6 3.05 g/kg 0.05 0.12 post excision weight measurement 0.0 0 100718 2519
SR/NEisSlc urine total protein excretion rate to body weight ratio controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. total urine protein amount male 77 days 19 3.4 mg/d/100 g 0.21 0.9 urine protein analysis 0.0 0 102477 2689