Phenominer Database Results (27 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Site Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Experiment Notes Record ID Study ID
SS/JrHsdMcwi middle cerebral artery inner diameter angiotensin II (3 ng/kg/min) (for 3 days) then controlled calcium ion content physiological salt solution perfusate (0 %) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 5 247.0 um 7.8 17.44 ex vivo videomicroscopy 0.0 0 69574 732
SS/JrHsdMcwi middle cerebral artery inner diameter controlled tempol content drinking water (15 mg/kg/d) (for 3 days) then physiological salt solution perfusate Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 6 133.0 um 3.4 8.33 ex vivo videomicroscopy 0.0 0 69582 732
SS/JrHsdMcwi middle cerebral artery inner diameter controlled captopril content drinking water (100 mg/kg/d) (for 3 days) then physiological salt solution perfusate Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 6 145.0 um 8.4 20.58 ex vivo videomicroscopy 0.0 0 69561 732
SS/JrHsdMcwi middle cerebral artery inner diameter controlled tempol content drinking water (15 mg/kg/d) (for 3 days) then controlled calcium ion content physiological salt solution perfusate (0 %) then NG-nitroarginine methyl ester (100 umol/l) (for 0.3 hours) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 6 246.0 um 8.9 21.8 ex vivo videomicroscopy 0.0 0 69586 732
SS/JrHsdMcwi resting tone of middle cerebral artery controlled captopril content drinking water (100 mg/kg/d) (for 3 days) then controlled calcium ion content physiological salt solution perfusate (0 %) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 6 [(Dmax - Drest) /Dmax] x 100 41.0 % 3.3 8.08 ex vivo videomicroscopy 0.0 0 69563 732
SS/JrHsdMcwi resting tone of middle cerebral artery angiotensin II (3 ng/kg/min) (for 3 days) then controlled calcium ion content physiological salt solution perfusate (0 %) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 5 [(Dmax - Drest) /Dmax] x 100 37.0 % 1.5 3.35 ex vivo videomicroscopy 0.0 0 69575 732
SS/JrHsdMcwi middle cerebral artery inner diameter controlled calcium ion content physiological salt solution perfusate (0 %) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 9 252.0 um 3.4 10.2 ex vivo videomicroscopy 0.0 0 67245 732
SS/JrHsdMcwi middle cerebral artery inner diameter controlled losartan content drinking water (20 mg/kg/d) (for 7 days) then controlled calcium ion content physiological salt solution perfusate (0 %) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 7 237.0 um 6.6 17.46 ex vivo videomicroscopy 0.0 0 69568 732
SS/JrHsdMcwi middle cerebral artery inner diameter angiotensin II (3 ng/kg/min) (for 3 days) then physiological salt solution perfusate Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 6 157.0 um 2.0 4.9 ex vivo videomicroscopy 0.0 0 69573 732
SS/JrHsdMcwi renal afferent arteriole diameter controlled sodium chloride content diet (1 %) (between 70 and 91 days) then controlled ex vivo artery perfusion pressure (60 mmHg) (for 0.1 hours) Miller B, et al., J Clin Invest. 2016 Jul 1;126(7):2533-46. doi: 10.1172/JCI75079. Epub 2016 Jun 6. kidney arteriole morphology trait not specified 91 days-133 days 9 19.8 um 0.9 2.7 ex vivo videomicroscopy renal afferent arteriole 120.0 0 ex vivo videomicroscopy (MMO:0000319) renal afferent arteriole diameter () renal arteriole morphology trait 106494 3030
SS/JrHsdMcwi renal afferent arteriole diameter controlled sodium chloride content diet (1 %) (between 70 and 91 days) then controlled ex vivo artery perfusion pressure (60 mmHg) (for 0.1 hours) Miller B, et al., J Clin Invest. 2016 Jul 1;126(7):2533-46. doi: 10.1172/JCI75079. Epub 2016 Jun 6. kidney arteriole morphology trait not specified 91 days-133 days 10 24.6 um 0.8 2.53 ex vivo videomicroscopy renal afferent arteriole 120.0 0 ex vivo videomicroscopy (MMO:0000319) renal afferent arteriole diameter (CMO:0003725) renal arteriole morphology trait 106504 3030
SS/JrHsdMcwi resting tone of middle cerebral artery 0.9% sodium chloride solution (for 3 days) then controlled calcium ion content physiological salt solution perfusate (0 %) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 6 [(Dmax - Drest) /Dmax] x 100 38.0 % 2.1 5.14 ex vivo videomicroscopy 0.0 0 69572 732
SS/JrHsdMcwi resting tone of middle cerebral artery controlled tempol content drinking water (15 mg/kg/d) (for 3 days) then controlled calcium ion content physiological salt solution perfusate (0 %) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 5 [(Dmax - Drest) /Dmax] x 100 48.0 % 1.9 4.25 ex vivo videomicroscopy 0.0 0 69584 732
SS/JrHsdMcwi middle cerebral artery inner diameter controlled captopril content drinking water (100 mg/kg/d) (for 3 days) then controlled calcium ion content physiological salt solution perfusate (0 %) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 6 245.0 um 6.1 14.94 ex vivo videomicroscopy 0.0 0 69562 732
SS/JrHsdMcwi middle cerebral artery inner diameter 0.9% sodium chloride solution (for 3 days) then physiological salt solution perfusate Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 6 155.0 um 8.6 21.07 ex vivo videomicroscopy 0.0 0 69570 732
SS/JrHsdMcwi middle cerebral artery inner diameter 0.9% sodium chloride solution (for 3 days) then controlled calcium ion content physiological salt solution perfusate (0 %) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 6 249.0 um 8.5 20.82 ex vivo videomicroscopy 0.0 0 69571 732
SS/JrHsdMcwi renal afferent arteriole diameter controlled sodium chloride content diet (1 %) (between 70 and 91 days) then controlled ex vivo artery perfusion pressure (60 mmHg) (for 0.1 hours) Miller B, et al., J Clin Invest. 2016 Jul 1;126(7):2533-46. doi: 10.1172/JCI75079. Epub 2016 Jun 6. kidney arteriole morphology trait not specified 91 days-133 days 8 24.1 um 0.8 2.26 ex vivo videomicroscopy renal afferent arteriole 120.0 0 ex vivo videomicroscopy (MMO:0000319) renal afferent arteriole diameter (CMO:0003725) renal arteriole morphology trait 106499 3030
SS/JrHsdMcwi resting tone of middle cerebral artery angiotensin II (3 ng/kg/min) (for 3 days) then controlled calcium ion content physiological salt solution perfusate (0 %) then NG-nitroarginine methyl ester (100 umol/l) (for 0.3 hours) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 5 [(Dmax - Drest) /Dmax] x 100 54.0 % 2.2 4.92 ex vivo videomicroscopy 0.0 0 69578 732
SS/JrHsdMcwi middle cerebral artery inner diameter physiological salt solution perfusate Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 9 146.0 um 5.4 16.2 ex vivo videomicroscopy 0.0 0 67244 732
SS/JrHsdMcwi middle cerebral artery inner diameter angiotensin II (3 ng/kg/min) (for 3 days) then controlled calcium ion content physiological salt solution perfusate (0 %) then NG-nitroarginine methyl ester (100 umol/l) (for 0.3 hours) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 5 246.0 um 3.7 8.27 ex vivo videomicroscopy 0.0 0 69577 732
SS/JrHsdMcwi middle cerebral artery inner diameter controlled tempol content drinking water (15 mg/kg/d) (for 3 days) then controlled calcium ion content physiological salt solution perfusate (0 %) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 5 255.0 um 2.9 6.48 ex vivo videomicroscopy 0.0 0 69583 732
SS/JrHsdMcwi middle cerebral artery inner diameter controlled tempol content drinking water (15 mg/kg/d) (for 3 days) then physiological salt solution perfusate then NG-nitroarginine methyl ester (100 umol/l) (for 0.3 hours) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 6 138.0 um 10.1 24.74 ex vivo videomicroscopy 0.0 0 69585 732
SS/JrHsdMcwi resting tone of middle cerebral artery controlled tempol content drinking water (15 mg/kg/d) (for 3 days) then controlled calcium ion content physiological salt solution perfusate (0 %) then NG-nitroarginine methyl ester (100 umol/l) (for 0.3 hours) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 6 [(Dmax - Drest) /Dmax] x 100 44.0 % 3.3 8.08 ex vivo videomicroscopy 0.0 0 69587 732
SS/JrHsdMcwi resting tone of middle cerebral artery controlled calcium ion content physiological salt solution perfusate (0 %) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 9 [(Dmax - Drest) /Dmax] x 100 42.0 % 3.3 9.9 ex vivo videomicroscopy 0.0 0 67246 732
SS/JrHsdMcwi middle cerebral artery inner diameter controlled losartan content drinking water (20 mg/kg/d) (for 7 days) then physiological salt solution perfusate Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 7 147.0 um 2.3 6.09 ex vivo videomicroscopy 0.0 0 69567 732
SS/JrHsdMcwi resting tone of middle cerebral artery controlled losartan content drinking water (20 mg/kg/d) (for 7 days) then controlled calcium ion content physiological salt solution perfusate (0 %) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 7 [(Dmax - Drest) /Dmax] x 100 38.0 % 2.1 5.56 ex vivo videomicroscopy 0.0 0 69569 732
SS/JrHsdMcwi middle cerebral artery inner diameter angiotensin II (3 ng/kg/min) (for 3 days) then physiological salt solution perfusate then NG-nitroarginine methyl ester (100 umol/l) (for 0.3 hours) Durand MJ, et al., Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1865-74. Epub 2010 Sep 17. cerebral artery size trait male 63 days-98 days 5 113.0 um 4.2 9.39 ex vivo videomicroscopy 0.0 0 69576 732