SHR/N-cp |
serum glucose level |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 112 and 126 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
blood glucose amount |
male |
140 days-168 days |
8 |
145.2 |
mg/dl |
23.6 |
66.74 |
serum glucose analysis |
0.0 |
0 |
101505 |
2601 |
SHR/N-cp |
serum glucose level |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
blood glucose amount |
male |
168 days-196 days |
8 |
130.68 |
mg/dl |
21.78 |
61.6 |
serum glucose analysis |
0.0 |
0 |
101508 |
2601 |
SHR/N-cp |
serum glucose level |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 112 and 126 days) then perindopril (0.25-0.5 mg/kg/d) (between 56 and 70 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
blood glucose amount |
male |
140 days-168 days |
8 |
179.69 |
mg/dl |
21.78 |
61.6 |
serum glucose analysis |
0.0 |
0 |
101506 |
2601 |
SHR/N-cp |
serum glucose level |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then perindopril (0.25-0.5 mg/kg/d) (between 84 and 98 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
blood glucose amount |
male |
168 days-196 days |
8 |
139.76 |
mg/dl |
18.15 |
51.34 |
serum glucose analysis |
0.0 |
0 |
101509 |
2601 |
SHR/N-cp |
both kidneys wet weight to body weight ratio |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then perindopril (0.25-0.5 mg/kg/d) (between 84 and 98 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
kidney mass |
male |
168 days-196 days |
8 |
1.67 |
g/kg |
0.1 |
0.28 |
post excision weight measurement |
0.0 |
0 |
101524 |
2601 |
SHR/N-cp |
kidney sclerotic glomeruli count to total glomeruli count ratio |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
kidney glomerulus integrity trait |
male |
168 days-196 days |
8 |
16.0 |
% |
3.0 |
8.49 |
ex vivo light microscopy with histochemistry |
0.0 |
0 |
101526 |
2601 |
SHR/N-cp |
plasma renin activity level |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then controlled hydralazine content drinking water (30 mg/l) (between 84 and 98 days) and hydralazine (50 mg/l) (between 84 and 98 days) and reserpine (4 mg/l) (between 84 and 98 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
renin activity |
male |
140 days-168 days |
8 |
38.0 |
ng/ml/h |
2.0 |
5.66 |
radioimmunoassay |
0.0 |
0 |
101534 |
2601 |
SHR/N-cp |
both kidneys wet weight to body weight ratio |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then controlled hydralazine content drinking water (30 mg/l) (between 84 and 98 days) and hydralazine (50 mg/l) (between 84 and 98 days) and reserpine (4 mg/l) (between 84 and 98 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
kidney mass |
male |
140 days-168 days |
8 |
1.83 |
g/kg |
0.31 |
0.88 |
post excision weight measurement |
0.0 |
0 |
101525 |
2601 |
SHR/N-cp |
plasma renin activity level |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
renin activity |
male |
168 days-196 days |
8 |
11.0 |
ng/ml/h |
2.0 |
5.66 |
radioimmunoassay |
0.0 |
0 |
101532 |
2601 |
SHR/N-cp |
kidney sclerotic glomeruli count to total glomeruli count ratio |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then controlled hydralazine content drinking water (30 mg/l) (between 84 and 98 days) and hydralazine (50 mg/l) (between 84 and 98 days) and reserpine (4 mg/l) (between 84 and 98 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
kidney glomerulus integrity trait |
male |
140 days-168 days |
8 |
4.0 |
% |
1.0 |
2.83 |
ex vivo light microscopy with histochemistry |
0.0 |
0 |
101528 |
2601 |
SHR/N-cp |
serum glucose level |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 84 and 98 days) then perindopril (0.25-0.5 mg/kg/d) (between 28 and 42 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
blood glucose amount |
male |
112 days-140 days |
8 |
192.39 |
mg/dl |
29.04 |
82.14 |
serum glucose analysis |
0.0 |
0 |
101503 |
2601 |
SHR/N-cp |
kidney sclerotic glomeruli count to total glomeruli count ratio |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then perindopril (0.25-0.5 mg/kg/d) (between 84 and 98 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
kidney glomerulus integrity trait |
male |
168 days-196 days |
8 |
9.0 |
% |
4.0 |
11.31 |
ex vivo light microscopy with histochemistry |
0.0 |
0 |
101527 |
2601 |
SHR/N-cp |
serum glucose level |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then controlled hydralazine content drinking water (30 mg/l) (between 84 and 98 days) and hydralazine (50 mg/l) (between 84 and 98 days) and reserpine (4 mg/l) (between 84 and 98 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
blood glucose amount |
male |
140 days-168 days |
8 |
139.76 |
mg/dl |
29.04 |
82.14 |
serum glucose analysis |
0.0 |
0 |
101510 |
2601 |
SHR/N-cp |
serum glucose level |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 42 and 56 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
blood glucose amount |
male |
70 days-98 days |
8 |
185.13 |
mg/dl |
32.67 |
92.4 |
serum glucose analysis |
0.0 |
0 |
101499 |
2601 |
SHR/N-cp |
serum glucose level |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 42 and 56 days) then perindopril (0.25-0.5 mg/kg/d) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
blood glucose amount |
male |
70 days-98 days |
8 |
154.28 |
mg/dl |
19.97 |
56.47 |
serum glucose analysis |
0.0 |
0 |
101500 |
2601 |
SHR/N-cp |
serum glucose level |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 42 and 56 days) then controlled hydralazine content drinking water (30 mg/l) and hydralazine (50 mg/l) and reserpine (4 mg/l) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
blood glucose amount |
male |
70 days-98 days |
8 |
139.76 |
mg/dl |
14.52 |
41.07 |
serum glucose analysis |
0.0 |
0 |
101501 |
2601 |
SHR/N-cp |
both kidneys wet weight to body weight ratio |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
kidney mass |
male |
168 days-196 days |
8 |
1.88 |
g/kg |
0.1 |
0.28 |
post excision weight measurement |
0.0 |
0 |
101523 |
2601 |
SHR/N-cp |
plasma renin activity level |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then perindopril (0.25-0.5 mg/kg/d) (between 84 and 98 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
renin activity |
male |
168 days-196 days |
8 |
52.0 |
ng/ml/h |
8.0 |
22.63 |
radioimmunoassay |
0.0 |
0 |
101533 |
2601 |
SHR/N-cp |
serum glucose level |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 84 and 98 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
blood glucose amount |
male |
112 days-140 days |
8 |
150.65 |
mg/dl |
23.6 |
66.74 |
serum glucose analysis |
0.0 |
0 |
101502 |
2601 |
SHR/N-cp |
serum glucose level |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 112 and 126 days) then controlled hydralazine content drinking water (30 mg/l) (between 56 and 70 days) and hydralazine (50 mg/l) (between 56 and 70 days) and reserpine (4 mg/l) (between 56 and 70 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
blood glucose amount |
male |
140 days-168 days |
8 |
157.91 |
mg/dl |
34.49 |
97.54 |
serum glucose analysis |
0.0 |
0 |
101507 |
2601 |
SHR/N-cp |
serum glucose level |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 84 and 98 days) then controlled hydralazine content drinking water (30 mg/l) (between 28 and 42 days) and hydralazine (50 mg/l) (between 28 and 42 days) and reserpine (4 mg/l) (between 28 and 42 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
blood glucose amount |
male |
112 days-140 days |
8 |
137.94 |
mg/dl |
30.86 |
87.27 |
serum glucose analysis |
0.0 |
0 |
101504 |
2601 |