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Strain |
Phenotype |
Conditions |
Study |
Experiment Name |
Sex |
Age |
# of Animals |
Value |
Units |
SEM |
SD |
Method |
Method Duration |
Post Insult Type |
Post Insult Time Value |
Post Insult Time Unit |
Clinical Measurement Notes |
Record ID |
Study ID |
SD |
percentage of study population developing anorectal malformation during a period of time |
in utero condition (for 7 days) and corn oil (for 7 days) |
Jiang JT, et al., Toxicology. 2015 Dec 2;338:77-85. doi: 10.1016/j.tox.2015.10.006. Epub 2015 Oct 26. |
anorectal integrity trait |
male |
1 days
| 0 |
0.0 |
% |
|
|
ex vivo light microscopy with histochemistry |
1.0 |
|
0 |
|
anorectal malformation incidence |
98734 |
2158 |
SD |
kidney sclerotic glomeruli count to total glomeruli count ratio |
sham surgical control condition (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney glomerulus integrity trait |
male |
0 days
| 6 |
1.9 |
% |
0.49 |
1.2 |
ex vivo light microscopy with histochemistry |
0.0 |
sham unx |
28 |
days |
|
101603 |
2602 |
SD |
kidney sclerotic glomeruli count to total glomeruli count ratio |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney glomerulus integrity trait |
male |
0 days
| 7 |
4.7 |
% |
1.97 |
5.2 |
ex vivo light microscopy with histochemistry |
0.0 |
unx |
28 |
days |
|
101605 |
2602 |
SD |
percentage of study population developing anorectal malformation during a period of time |
in utero condition (for 7 days) and dibutyl phthalate (850 mg/kg/d) (for 7 days) |
Jiang JT, et al., Toxicology. 2015 Dec 2;338:77-85. doi: 10.1016/j.tox.2015.10.006. Epub 2015 Oct 26. |
anorectal integrity trait |
male |
1 days
| 43 |
39.5 |
% |
|
|
ex vivo light microscopy with histochemistry |
1.0 |
|
0 |
|
anorectal malformation incidence |
98733 |
2158 |
SD |
kidney sclerotic glomeruli count to total glomeruli count ratio |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney glomerulus integrity trait |
male |
0 days
| 8 |
31.0 |
% |
5.66 |
16.0 |
ex vivo light microscopy with histochemistry |
0.0 |
unx |
28 |
days |
|
101629 |
2602 |
SD |
kidney sclerotic glomeruli count to total glomeruli count ratio |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney glomerulus integrity trait |
male |
0 days
| 7 |
37.2 |
% |
10.02 |
26.5 |
ex vivo light microscopy with histochemistry |
0.0 |
unx |
28 |
days |
|
101604 |
2602 |
SD |
kidney sclerotic glomeruli count to total glomeruli count ratio |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney glomerulus integrity trait |
male |
0 days
| 6 |
25.3 |
% |
4.53 |
11.1 |
ex vivo light microscopy with histochemistry |
0.0 |
unx |
28 |
days |
|
101606 |
2602 |
SD |
kidney sclerotic glomeruli count to total glomeruli count ratio |
unilateral nephrectomy (for 28 days) then spironolactone (5.56 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney glomerulus integrity trait |
male |
0 days
| 8 |
26.0 |
% |
3.89 |
11.0 |
ex vivo light microscopy with histochemistry |
0.0 |
unx |
28 |
days |
|
101630 |
2602 |
|