ACI/NJcl |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
42 days
| 6 |
|
120.5 |
g |
2.61 |
6.4 |
whole body digital scale |
|
0 |
|
|
70734 |
21 |
ACI/NJcl |
heart weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
heart mass |
male |
70 days
| 6 |
|
3.67 |
g/kg |
0.13 |
0.31 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
71844 |
41 |
ACI/NJcl |
both kidneys wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
kidney mass |
male |
70 days
| 6 |
|
1.41 |
g |
0.07 |
0.16 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
71849 |
41 |
ACI/NJcl |
spleen wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
spleen mass |
male |
70 days
| 6 |
|
0.36 |
g |
0.01 |
0.02 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
71853 |
41 |
ACI/NJcl |
both testes wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
testis mass |
male |
70 days
| 6 |
|
2.0 |
g |
0.15 |
0.36 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
71855 |
41 |
ACI/NJcl |
plasma aspartate aminotransferase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood aspartate transaminase amount |
male |
70 days
| 6 |
|
82.0 |
U/l |
6.12 |
15.0 |
automated plasma analysis |
|
0 |
PMID:15591307 |
|
77499 |
1498 |
ACI/NJcl |
plasma albumin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood albumin amount |
male |
70 days
| 6 |
|
0.39 |
g/l |
0.0 |
0.01 |
automated plasma albumin analysis |
|
0 |
Hitachi, model 7170 |
|
77503 |
1498 |
ACI/NJcl |
plasma sodium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood sodium amount |
male |
70 days
| 6 |
|
146.5 |
mmol/l |
0.53 |
1.3 |
automated blood electrolyte analysis |
|
0 |
Analytical intruments, PVA alpha II |
|
77515 |
1498 |
ACI/NJcl |
urine potassium excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine potassium amount |
male |
63 days
| 6 |
|
261.0 |
uEq/100g/6 hrs |
20.41 |
50.0 |
automated urine analysis |
|
0 |
Analytical intruments, PVA alpha II |
|
95009 |
1662 |
ACI/NJcl |
urine chloride excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine chloride amount |
male |
63 days
| 6 |
|
427.0 |
uEq/100g/6 hrs |
22.86 |
56.0 |
automated urine analysis |
|
0 |
|
|
95011 |
1662 |
ACI/NJcl |
red blood cell count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte quantity |
male |
70 days
| 6 |
|
8.72 |
x 10E6 cells/ul |
0.12 |
0.29 |
automated cell/particle size/count analysis method |
|
0 |
Sysmex, F-800 type |
|
77489 |
1498 |
ACI/NJcl |
plasma low density lipoprotein cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood LDL cholesterol amount |
male |
70 days
| 6 |
|
8.0 |
mg/dl |
0.82 |
2.0 |
automated plasma analysis |
|
0 |
PMID:15591307 |
|
77508 |
1498 |
ACI/NJcl |
plasma total bilirubin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood bilirubin amount |
male |
70 days
| 6 |
|
0.02 |
mg/dl |
0.01 |
0.02 |
automated plasma analysis |
|
0 |
PMID:15591307 |
total plasma bilirubin level |
77510 |
1498 |
ACI/NJcl |
blood segmented neutrophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
neutrophil quantity |
male |
70 days
| 6 |
|
19.0 |
% |
2.04 |
5.0 |
automated differential white blood cell count test |
|
0 |
May-Giemsa staining |
segmented neutrophil % |
77521 |
1498 |
ACI/NJcl |
heart wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
heart mass |
male |
70 days
| 6 |
|
0.73 |
g |
0.02 |
0.06 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
71843 |
41 |
ACI/NJcl |
lung wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
lung mass |
male |
70 days
| 6 |
|
0.75 |
g |
0.04 |
0.11 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
71845 |
41 |
ACI/NJcl |
liver wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
liver mass |
male |
70 days
| 6 |
|
5.21 |
g |
0.21 |
0.51 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
71847 |
41 |
ACI/NJcl |
both kidneys wet weight as percentage of body weight |
specific pathogen-free condition |
NBRP Organ Weight data |
kidney mass |
male |
70 days
| 6 |
|
0.71 |
% |
0.02 |
0.06 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
71850 |
41 |
ACI/NJcl |
hematocrit |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte quantity |
male |
70 days
| 6 |
|
51.1 |
% |
0.45 |
1.1 |
automated cell/particle size/count analysis method |
|
0 |
Sysmex, F-800 type |
|
77491 |
1498 |
ACI/NJcl |
mean corpuscular hemoglobin |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70 days
| 6 |
|
17.3 |
pg |
0.12 |
0.3 |
automated cell/particle size/count analysis method |
|
0 |
Sysmex, F-800 type |
|
77493 |
1498 |
ACI/NJcl |
white blood cell count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
leukocyte quantity |
male |
70 days
| 6 |
|
3.7 |
x 1000 cells/ul |
0.49 |
1.2 |
automated cell/particle size/count analysis method |
|
0 |
Sysmex, F-800 type |
|
77495 |
1498 |
ACI/NJcl |
plasma alkaline phosphatase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood alkaline phosphatase amount |
male |
70 days
| 6 |
|
265.0 |
IU/l |
7.35 |
18.0 |
automated plasma analysis |
|
0 |
PMID:15591307 |
|
77501 |
1498 |
ACI/NJcl |
total plasma calcium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood calcium amount |
male |
70 days
| 6 |
|
9.6 |
mg/dl |
0.2 |
0.5 |
automated blood electrolyte analysis |
|
0 |
Hitachi, model 7170 |
|
77514 |
1498 |
ACI/NJcl |
blood eosinophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
eosinophil quantity |
male |
70 days
| 6 |
|
1.0 |
% |
0.41 |
1.0 |
automated differential white blood cell count test |
|
0 |
May-Giemsa staining |
|
77519 |
1498 |
ACI/NJcl |
blood band neutrophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
neutrophil quantity |
male |
70 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
0 |
May-Giemsa staining |
band neutrophil % |
77520 |
1498 |
ACI/NJcl |
blood lymphocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
lymphocyte quantity |
male |
70 days
| 6 |
|
81.0 |
% |
2.04 |
5.0 |
automated differential white blood cell count test |
|
0 |
May-Giemsa staining |
|
77522 |
1498 |
ACI/NJcl |
urine sodium level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine sodium amount |
male |
63 days
| 6 |
|
138.6 |
mmol/l |
9.55 |
23.4 |
automated urine analysis |
|
0 |
Analytical intruments, PVA alpha II |
|
95006 |
1662 |
ACI/NJcl |
urine potassium level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine potassium amount |
male |
63 days
| 6 |
|
108.8 |
mmol/l |
6.86 |
16.8 |
automated urine analysis |
|
0 |
Analytical intruments, PVA alpha II |
|
95008 |
1662 |
ACI/NJcl |
urine chloride level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine chloride amount |
male |
63 days
| 6 |
|
179.0 |
mEq/L |
11.84 |
29.0 |
automated urine analysis |
|
0 |
|
|
95010 |
1662 |
ACI/NJcl |
heart rate |
specific pathogen-free condition |
NBRP Blood Pressure and Heart Rate data |
heart pumping trait |
male |
56 days-70 days |
6 |
serial mean |
463.0 |
beats/min |
16.74 |
41.0 |
tail cuff photoplethysmography |
|
0 |
NP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japan |
|
74989 |
14 |
ACI/NJcl |
plasma total protein level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood total protein amount |
male |
70 days
| 6 |
|
58.0 |
mg/ml |
0.41 |
1.0 |
automated plasma total protein analysis |
|
0 |
Hitachi, model 7170 |
|
77502 |
1498 |
ACI/NJcl |
blood basophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
basophil quantity |
male |
70 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
0 |
May-Giemsa staining |
|
77518 |
1498 |
ACI/NJcl |
spleen weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
spleen mass |
male |
70 days
| 6 |
|
0.18 |
% |
0.0 |
0.01 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
71854 |
41 |
ACI/NJcl |
both testes wet weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
testis mass |
male |
70 days
| 6 |
|
1.0 |
% |
0.07 |
0.17 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
71856 |
41 |
ACI/NJcl |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
70 days
| 6 |
|
204.4 |
g |
5.31 |
13.0 |
whole body digital scale |
|
0 |
|
|
70736 |
21 |
ACI/NJcl |
blood hemoglobin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70 days
| 6 |
|
15.1 |
g/dl |
0.16 |
0.4 |
automated cell/particle size/count analysis method |
|
0 |
Sysmex, F-800 type |
|
77490 |
1498 |
ACI/NJcl |
systolic blood pressure |
specific pathogen-free condition |
NBRP Blood Pressure and Heart Rate data |
arterial blood pressure trait |
male |
56 days-70 days |
6 |
serial mean |
157.0 |
mmHg |
6.12 |
15.0 |
tail cuff photoplethysmography |
|
0 |
NP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japan |
|
74988 |
14 |
ACI/NJcl |
mean corpuscular hemoglobin concentration |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70 days
| 6 |
|
29.5 |
g/dl |
0.12 |
0.3 |
automated cell/particle size/count analysis method |
|
0 |
Sysmex, F-800 type |
|
77494 |
1498 |
ACI/NJcl |
prothrombin time |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood coagulation trait |
male |
70 days
| 6 |
|
17.3 |
s |
0.12 |
0.3 |
automated coagulometer method |
|
0 |
Sysmex, CA-3000 type |
|
77497 |
1498 |
ACI/NJcl |
body temperature |
specific pathogen-free condition |
NBRP Body Temperature data |
body temperature trait |
male |
56 days-70 days |
6 |
serial mean |
38.0 |
degrees C |
0.12 |
0.3 |
digital rectal thermometry |
|
0 |
|
|
74990 |
22 |
ACI/NJcl |
brain wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
brain mass |
male |
70 days
| 6 |
|
1.74 |
g |
0.03 |
0.07 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
71841 |
41 |
ACI/NJcl |
both adrenal glands weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
adrenal gland mass |
male |
70 days
| 6 |
|
19.5 |
mg/100g |
0.78 |
1.9 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
71852 |
41 |
ACI/NJcl |
platelet count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
platelet quantity |
male |
70 days
| 6 |
|
1206.0 |
x 1000 /ul |
54.71 |
134.0 |
automated cell/particle size/count analysis method |
|
0 |
Sysmex, F-800 type |
|
77496 |
1498 |
ACI/NJcl |
activated partial thromboplastin time |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood coagulation trait |
male |
70 days
| 6 |
|
13.2 |
s |
1.47 |
3.6 |
automated coagulometer method |
|
0 |
Sysmex, CA-3000 type |
|
77498 |
1498 |
ACI/NJcl |
plasma albumin to plasma total protein ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood albumin amount |
male |
70 days
| 6 |
|
2.04 |
null |
0.07 |
0.18 |
automated plasma protein analysis |
|
0 |
Hitachi, model 7170 |
plasma albumin to plasma total protein ratio |
77504 |
1498 |
ACI/NJcl |
plasma total cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood cholesterol amount |
male |
70 days
| 6 |
|
63.0 |
mg/dl |
2.86 |
7.0 |
automated plasma analysis |
|
0 |
PMID:15591307 |
|
77506 |
1498 |
ACI/NJcl |
plasma triglyceride level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood triglyceride amount |
male |
70 days
| 6 |
|
0.79 |
mmol/l |
0.06 |
0.15 |
automated plasma analysis |
|
0 |
PMID:15591307 |
|
77509 |
1498 |
ACI/NJcl |
plasma urea nitrogen level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood urea nitrogen amount |
male |
70 days
| 6 |
|
7.96 |
mmol/l |
0.36 |
0.89 |
automated plasma analysis |
|
0 |
PMID:15591307 |
|
77511 |
1498 |
ACI/NJcl |
plasma creatinine level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood creatinine amount |
male |
70 days
| 6 |
|
0.27 |
mg/dl |
0.0 |
0.01 |
automated plasma creatinine analysis |
|
0 |
Hitachi, model 7170 |
|
77512 |
1498 |
ACI/NJcl |
timed urine volume |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine output |
male |
63 days
| 6 |
|
19.2 |
ml/d |
1.52 |
3.72 |
metabolic cage urine volume measurement method |
|
0 |
|
|
95004 |
1662 |
ACI/NJcl |
non-specified leukocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
leukocyte quantity |
male |
70 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
0 |
May-Giemsa staining |
unidentified differential wbc |
77524 |
1498 |
ACI/NJcl |
lung weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
lung mass |
male |
70 days
| 6 |
|
0.38 |
% |
0.02 |
0.05 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
71846 |
41 |
ACI/NJcl |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
35 days
| 6 |
|
84.5 |
g |
2.08 |
5.1 |
whole body digital scale |
|
0 |
|
|
70735 |
21 |
ACI/NJcl |
brain weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
brain mass |
male |
70 days
| 6 |
|
0.88 |
% |
0.01 |
0.03 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
71842 |
41 |
ACI/NJcl |
plasma high density lipoprotein cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood HDL cholesterol amount |
male |
70 days
| 6 |
|
45.7 |
mg/dl |
2.37 |
5.8 |
automated plasma analysis |
|
0 |
PMID:15591307 |
|
77507 |
1498 |
ACI/NJcl |
plasma chloride level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood chloride amount |
male |
70 days
| 6 |
|
106.0 |
mmol/l |
0.82 |
2.0 |
automated blood electrolyte analysis |
|
0 |
Analytical intruments, PVA alpha II |
|
77517 |
1498 |
ACI/NJcl |
blood monocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
monocyte quantity |
male |
70 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
0 |
May-Giemsa staining |
|
77523 |
1498 |
ACI/NJcl |
timed urine volume to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine output |
male |
63 days
| 6 |
|
0.07 |
ul/min/g |
0.0 |
0.01 |
metabolic cage urine volume measurement method |
|
0 |
|
|
95005 |
1662 |
ACI/NJcl |
urine sodium excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine sodium amount |
male |
63 days
| 6 |
|
0.01 |
uEq/min/g |
0.0 |
0.0 |
automated urine analysis |
|
0 |
Analytical intruments, PVA alpha II |
|
95007 |
1662 |
ACI/NJcl |
percentage of study population developing stomach tumors during a period of time |
controlled N-methyl-N'-nitro-N-nitrosoguanidine content drinking water (83 mg/l) (for 224 days) |
Ushijima T, et al., Cancer Res 2000 Feb 15;60(4):1092-6. |
stomach integrity trait |
not specified |
56 days-560 days |
21 |
|
76.0 |
% |
|
|
necropsy |
0.0 |
0 |
|
|
84753 |
1478 |
ACI/NJcl |
mean corpuscular volume |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte size trait |
male |
70 days
| 6 |
|
58.6 |
fl |
0.53 |
1.3 |
automated cell/particle size/count analysis method |
|
0 |
Sysmex, F-800 type |
|
77492 |
1498 |
ACI/NJcl |
plasma alanine aminotransferase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood alanine transaminase amount |
male |
70 days
| 6 |
|
39.0 |
U/l |
6.12 |
15.0 |
automated plasma analysis |
|
0 |
PMID:15591307 |
|
77500 |
1498 |
ACI/NJcl |
plasma glucose level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood glucose amount |
male |
70 days
| 6 |
|
163.0 |
mg/dl |
12.66 |
31.0 |
automated plasma analysis |
|
0 |
PMID:15591307 |
|
77505 |
1498 |
ACI/NJcl |
plasma phosphate level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood phosphate amount |
male |
70 days
| 6 |
|
6.2 |
mg/dl |
0.53 |
1.3 |
automated blood electrolyte analysis |
|
0 |
Hitachi, model 7170 |
|
77513 |
1498 |
ACI/NJcl |
plasma potassium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood potassium amount |
male |
70 days
| 6 |
|
5.2 |
mmol/l |
0.8 |
1.97 |
automated blood electrolyte analysis |
|
0 |
Analytical intruments, PVA alpha II |
|
77516 |
1498 |
ACI/NJcl |
liver weight as percentage of body weight |
specific pathogen-free condition |
NBRP Organ Weight data |
liver mass |
male |
70 days
| 6 |
|
2.62 |
% |
0.06 |
0.14 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
71848 |
41 |
ACI/NJcl |
both adrenal glands wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
adrenal gland mass |
male |
70 days
| 6 |
|
38.7 |
mg |
1.63 |
4.0 |
Shimadzu electronic balance post excision weight measurement |
|
0 |
|
|
71851 |
41 |