DA/Slc |
urine total protein excretion rate |
anti-glomerular basement membrane antibody (500 ul) |
Kose H, et al., Exp Anim. 2009 Apr;58(2):193-8. |
total urine protein amount |
female |
61 days
| 10 |
|
1.92 |
mg/d |
|
|
urine protein analysis |
0.0 |
antibody injection |
5 |
days |
|
|
67684 |
307 |
DA/Slc |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
42 days
| 6 |
|
133.3 |
g |
3.02 |
7.4 |
whole body digital scale |
|
|
0 |
|
|
|
70670 |
21 |
DA/Slc |
heart weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
heart mass |
male |
70 days
| 6 |
|
4.04 |
g/kg |
0.15 |
0.37 |
Shimadzu electronic balance post excision weight measurement |
|
|
0 |
|
|
|
71494 |
41 |
DA/Slc |
spleen wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
spleen mass |
male |
70 days
| 6 |
|
0.33 |
g |
0.01 |
0.02 |
Shimadzu electronic balance post excision weight measurement |
|
|
0 |
|
|
|
71503 |
41 |
DA/Slc |
white blood cell count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
leukocyte quantity |
male |
70 days
| 6 |
|
6.1 |
x 1000 cells/ul |
0.94 |
2.3 |
automated cell/particle size/count analysis method |
|
|
0 |
|
Sysmex, F-800 type |
|
76703 |
1498 |
DA/Slc |
plasma low density lipoprotein cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood LDL cholesterol amount |
male |
70 days
| 6 |
|
14.0 |
mg/dl |
0.82 |
2.0 |
automated plasma analysis |
|
|
0 |
|
PMID:15591307 |
|
76716 |
1498 |
DA/Slc |
plasma total bilirubin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood bilirubin amount |
male |
70 days
| 6 |
|
0.05 |
mg/dl |
0.0 |
0.01 |
automated plasma analysis |
|
|
0 |
|
PMID:15591307 |
total plasma bilirubin level |
76718 |
1498 |
DA/Slc |
total plasma calcium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood calcium amount |
male |
70 days
| 6 |
|
9.2 |
mg/dl |
0.12 |
0.3 |
automated blood electrolyte analysis |
|
|
0 |
|
Hitachi, model 7170 |
|
76722 |
1498 |
DA/Slc |
blood lymphocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
lymphocyte quantity |
male |
70 days
| 6 |
|
88.0 |
% |
2.86 |
7.0 |
automated differential white blood cell count test |
|
|
0 |
|
May-Giemsa staining |
|
76730 |
1498 |
DA/Slc |
timed urine volume to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine output |
male |
63 days
| 6 |
|
0.04 |
ul/min/g |
0.0 |
0.01 |
metabolic cage urine volume measurement method |
|
|
0 |
|
|
|
94829 |
1662 |
DA/Slc |
urine sodium level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine sodium amount |
male |
63 days
| 6 |
|
164.5 |
mmol/l |
9.84 |
24.1 |
automated urine analysis |
|
|
0 |
|
Analytical intruments, PVA alpha II |
|
94830 |
1662 |
DA/Slc |
body temperature |
specific pathogen-free condition |
NBRP Body Temperature data |
body temperature trait |
male |
56 days-70 days |
6 |
serial mean |
38.4 |
degrees C |
0.12 |
0.3 |
digital rectal thermometry |
|
|
0 |
|
|
|
74924 |
22 |
DA/Slc |
heart wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
heart mass |
male |
70 days
| 6 |
|
0.75 |
g |
0.03 |
0.06 |
Shimadzu electronic balance post excision weight measurement |
|
|
0 |
|
|
|
71493 |
41 |
DA/Slc |
lung weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
lung mass |
male |
70 days
| 6 |
|
0.39 |
% |
0.01 |
0.02 |
Shimadzu electronic balance post excision weight measurement |
|
|
0 |
|
|
|
71496 |
41 |
DA/Slc |
both testes wet weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
testis mass |
male |
70 days
| 6 |
|
1.18 |
% |
0.02 |
0.06 |
Shimadzu electronic balance post excision weight measurement |
|
|
0 |
|
|
|
71506 |
41 |
DA/Slc |
plasma triglyceride level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood triglyceride amount |
male |
70 days
| 6 |
|
0.25 |
mmol/l |
0.05 |
0.11 |
automated plasma analysis |
|
|
0 |
|
PMID:15591307 |
|
76717 |
1498 |
DA/Slc |
blood band neutrophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
neutrophil quantity |
male |
70 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
|
0 |
|
May-Giemsa staining |
band neutrophil % |
76728 |
1498 |
DA/Slc |
kidney wet weight |
anti-glomerular basement membrane antibody (500 ul) |
Kose H, et al., Exp Anim. 2009 Apr;58(2):193-8. |
kidney mass |
female |
64 days
| 10 |
|
1.12 |
g |
|
|
post excision weight measurement |
0.0 |
antibody injection |
8 |
days |
|
|
67685 |
307 |
DA/Slc |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
35 days
| 6 |
|
92.8 |
g |
2.74 |
6.7 |
whole body digital scale |
|
|
0 |
|
|
|
70669 |
21 |
DA/Slc |
squamous cell carcinoma of the head and neck tumor number |
controlled 4-nitroquinoline N-oxide content drinking water (10 mg/l) (for 180 days) |
Hirano M, et al., Cancer Lett 2005 May 2;. |
head and neck integrity trait |
both |
42 days-222 days |
20 |
|
5.55 |
null |
0.4 |
1.79 |
necropsy |
0.0 |
|
0 |
|
|
180 day maximum |
70326 |
1339 |
DA/Slc |
brain weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
brain mass |
male |
70 days
| 6 |
|
1.0 |
% |
0.02 |
0.04 |
Shimadzu electronic balance post excision weight measurement |
|
|
0 |
|
|
|
71492 |
41 |
DA/Slc |
lung wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
lung mass |
male |
70 days
| 6 |
|
0.72 |
g |
0.01 |
0.03 |
Shimadzu electronic balance post excision weight measurement |
|
|
0 |
|
|
|
71495 |
41 |
DA/Slc |
liver wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
liver mass |
male |
70 days
| 6 |
|
4.51 |
g |
0.14 |
0.35 |
Shimadzu electronic balance post excision weight measurement |
|
|
0 |
|
|
|
71497 |
41 |
DA/Slc |
mean corpuscular hemoglobin concentration |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70 days
| 6 |
|
32.1 |
g/dl |
0.08 |
0.2 |
automated cell/particle size/count analysis method |
|
|
0 |
|
Sysmex, F-800 type |
|
76702 |
1498 |
DA/Slc |
blood basophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
basophil quantity |
male |
70 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
|
0 |
|
May-Giemsa staining |
|
76726 |
1498 |
DA/Slc |
urine sodium excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine sodium amount |
male |
63 days
| 6 |
|
0.01 |
uEq/min/g |
0.0 |
0.0 |
automated urine analysis |
|
|
0 |
|
Analytical intruments, PVA alpha II |
|
94831 |
1662 |
DA/Slc |
squamous cell carcinoma of the tongue maximum tumor diameter |
controlled 4-nitroquinoline N-oxide content drinking water (0.001 %) (for 0.1 hours) |
Tanuma J, et al., Cancer Res 1998 Apr 15;58(8):1660-4 |
tongue integrity trait |
both |
42 days-222 days |
47 |
|
12.77 |
mm |
0.65 |
4.49 |
necropsy |
0.0 |
|
0 |
|
until moribund or 180days of exp |
error not specified |
70397 |
1398 |
DA/Slc |
heart rate |
specific pathogen-free condition |
NBRP Blood Pressure and Heart Rate data |
heart pumping trait |
male |
56 days-70 days |
6 |
serial mean |
443.0 |
beats/min |
16.33 |
40.0 |
tail cuff photoplethysmography |
|
|
0 |
|
NP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japan |
|
74923 |
14 |
DA/Slc |
number of squamous cell tumors of the tongue with diameter greater than 3 mm |
controlled 4-nitroquinoline N-oxide content drinking water (10 mg/l) (for 180 days) |
Hirano M, et al., Cancer Lett 2005 May 2;. |
tongue integrity trait |
both |
42 days-222 days |
20 |
|
1.6 |
null |
0.17 |
0.75 |
necropsy |
0.0 |
|
0 |
|
|
180 day maximum |
70320 |
1339 |
DA/Slc |
both kidneys wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
kidney mass |
male |
70 days
| 6 |
|
1.24 |
g |
0.04 |
0.09 |
Shimadzu electronic balance post excision weight measurement |
|
|
0 |
|
|
|
71499 |
41 |
DA/Slc |
both adrenal glands weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
adrenal gland mass |
male |
70 days
| 6 |
|
19.1 |
mg/100g |
1.22 |
3.0 |
Shimadzu electronic balance post excision weight measurement |
|
|
0 |
|
|
|
71502 |
41 |
DA/Slc |
both testes wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
testis mass |
male |
70 days
| 6 |
|
2.18 |
g |
0.04 |
0.09 |
Shimadzu electronic balance post excision weight measurement |
|
|
0 |
|
|
|
71505 |
41 |
DA/Slc |
red blood cell count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte quantity |
male |
70 days
| 6 |
|
9.14 |
x 10E6 cells/ul |
0.18 |
0.45 |
automated cell/particle size/count analysis method |
|
|
0 |
|
Sysmex, F-800 type |
|
76697 |
1498 |
DA/Slc |
prothrombin time |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood coagulation trait |
male |
70 days
| 6 |
|
16.8 |
s |
0.12 |
0.3 |
automated coagulometer method |
|
|
0 |
|
Sysmex, CA-3000 type |
|
76705 |
1498 |
DA/Slc |
plasma albumin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood albumin amount |
male |
70 days
| 6 |
|
0.39 |
g/l |
0.01 |
0.02 |
automated plasma albumin analysis |
|
|
0 |
|
Hitachi, model 7170 |
|
76711 |
1498 |
DA/Slc |
plasma glucose level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood glucose amount |
male |
70 days
| 6 |
|
138.0 |
mg/dl |
4.49 |
11.0 |
automated plasma analysis |
|
|
0 |
|
PMID:15591307 |
|
76713 |
1498 |
DA/Slc |
plasma potassium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood potassium amount |
male |
70 days
| 6 |
|
4.27 |
mmol/l |
0.29 |
0.7 |
automated blood electrolyte analysis |
|
|
0 |
|
Analytical intruments, PVA alpha II |
|
76724 |
1498 |
DA/Slc |
blood eosinophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
eosinophil quantity |
male |
70 days
| 6 |
|
0.0 |
% |
0.41 |
1.0 |
automated differential white blood cell count test |
|
|
0 |
|
May-Giemsa staining |
|
76727 |
1498 |
DA/Slc |
urine chloride excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine chloride amount |
male |
63 days
| 6 |
|
275.0 |
uEq/100g/6 hrs |
23.27 |
57.0 |
automated urine analysis |
|
|
0 |
|
|
|
94835 |
1662 |
DA/Slc |
both adrenal glands wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
adrenal gland mass |
male |
70 days
| 6 |
|
35.2 |
mg |
2.16 |
5.3 |
Shimadzu electronic balance post excision weight measurement |
|
|
0 |
|
|
|
71501 |
41 |
DA/Slc |
spleen weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
spleen mass |
male |
70 days
| 6 |
|
0.18 |
% |
0.0 |
0.01 |
Shimadzu electronic balance post excision weight measurement |
|
|
0 |
|
|
|
71504 |
41 |
DA/Slc |
timed urine volume |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine output |
male |
63 days
| 6 |
|
11.08 |
ml/d |
0.83 |
2.04 |
metabolic cage urine volume measurement method |
|
|
0 |
|
|
|
94828 |
1662 |
DA/Slc |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
70 days
| 6 |
|
196.2 |
g |
3.96 |
9.7 |
whole body digital scale |
|
|
0 |
|
|
|
70668 |
21 |
DA/Slc |
squamous cell carcinoma of the head and neck tumor number |
controlled 4-nitroquinoline N-oxide content drinking water (0.001 %) (for 0.1 hours) |
Tanuma J, et al., Cancer Res 1998 Apr 15;58(8):1660-4 |
head and neck integrity trait |
both |
42 days-222 days |
47 |
|
3.34 |
null |
0.23 |
1.58 |
necropsy |
0.0 |
|
0 |
|
until moribund or 180days of exp |
error not specified |
70401 |
1398 |
DA/Slc |
hematocrit |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte quantity |
male |
70 days
| 6 |
|
48.2 |
% |
1.02 |
2.5 |
automated cell/particle size/count analysis method |
|
|
0 |
|
Sysmex, F-800 type |
|
76699 |
1498 |
DA/Slc |
mean corpuscular hemoglobin |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70 days
| 6 |
|
16.9 |
pg |
0.04 |
0.1 |
automated cell/particle size/count analysis method |
|
|
0 |
|
Sysmex, F-800 type |
|
76701 |
1498 |
DA/Slc |
plasma aspartate aminotransferase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood aspartate transaminase amount |
male |
70 days
| 6 |
|
166.0 |
U/l |
29.8 |
73.0 |
automated plasma analysis |
|
|
0 |
|
PMID:15591307 |
|
76707 |
1498 |
DA/Slc |
plasma chloride level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood chloride amount |
male |
70 days
| 6 |
|
106.0 |
mmol/l |
0.82 |
2.0 |
automated blood electrolyte analysis |
|
|
0 |
|
Analytical intruments, PVA alpha II |
|
76725 |
1498 |
DA/Slc |
body weight |
anti-glomerular basement membrane antibody (500 ul) |
Kose H, et al., Exp Anim. 2009 Apr;58(2):193-8. |
body mass |
female |
64 days
| 10 |
|
136.8 |
g |
|
|
body weighing method |
0.0 |
antibody injection |
8 |
days |
|
|
67689 |
307 |
DA/Slc |
number of squamous cell tumors of the tongue with diameter greater than 5 mm |
controlled 4-nitroquinoline N-oxide content drinking water (0.001 %) (for 0.1 hours) |
Tanuma J, et al., Cancer Res 1998 Apr 15;58(8):1660-4 |
tongue integrity trait |
both |
42 days-222 days |
47 |
|
1.17 |
null |
0.09 |
0.64 |
necropsy |
0.0 |
|
0 |
|
until moribund or 180days of exp |
error not specified |
70393 |
1398 |
DA/Slc |
brain wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
brain mass |
male |
70 days
| 6 |
|
1.85 |
g |
0.02 |
0.04 |
Shimadzu electronic balance post excision weight measurement |
|
|
0 |
|
|
|
71491 |
41 |
DA/Slc |
both kidneys wet weight as percentage of body weight |
specific pathogen-free condition |
NBRP Organ Weight data |
kidney mass |
male |
70 days
| 6 |
|
0.67 |
% |
0.01 |
0.03 |
Shimadzu electronic balance post excision weight measurement |
|
|
0 |
|
|
|
71500 |
41 |
DA/Slc |
blood hemoglobin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70 days
| 6 |
|
15.5 |
g/dl |
0.33 |
0.8 |
automated cell/particle size/count analysis method |
|
|
0 |
|
Sysmex, F-800 type |
|
76698 |
1498 |
DA/Slc |
mean corpuscular volume |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte size trait |
male |
70 days
| 6 |
|
52.7 |
fl |
0.2 |
0.5 |
automated cell/particle size/count analysis method |
|
|
0 |
|
Sysmex, F-800 type |
|
76700 |
1498 |
DA/Slc |
activated partial thromboplastin time |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood coagulation trait |
male |
70 days
| 6 |
|
12.0 |
s |
0.41 |
1.0 |
automated coagulometer method |
|
|
0 |
|
Sysmex, CA-3000 type |
|
76706 |
1498 |
DA/Slc |
plasma alanine aminotransferase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood alanine transaminase amount |
male |
70 days
| 6 |
|
114.0 |
U/l |
30.62 |
75.0 |
automated plasma analysis |
|
|
0 |
|
PMID:15591307 |
|
76708 |
1498 |
DA/Slc |
plasma total protein level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood total protein amount |
male |
70 days
| 6 |
|
60.0 |
mg/ml |
0.82 |
2.0 |
automated plasma total protein analysis |
|
|
0 |
|
Hitachi, model 7170 |
|
76710 |
1498 |
DA/Slc |
plasma total cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood cholesterol amount |
male |
70 days
| 6 |
|
75.0 |
mg/dl |
2.86 |
7.0 |
automated plasma analysis |
|
|
0 |
|
PMID:15591307 |
|
76714 |
1498 |
DA/Slc |
urine potassium level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine potassium amount |
male |
63 days
| 6 |
|
91.1 |
mmol/l |
5.59 |
13.7 |
automated urine analysis |
|
|
0 |
|
Analytical intruments, PVA alpha II |
|
94832 |
1662 |
DA/Slc |
urine chloride level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine chloride amount |
male |
63 days
| 6 |
|
195.0 |
mEq/L |
9.8 |
24.0 |
automated urine analysis |
|
|
0 |
|
|
|
94834 |
1662 |
DA/Slc |
liver weight as percentage of body weight |
specific pathogen-free condition |
NBRP Organ Weight data |
liver mass |
male |
70 days
| 6 |
|
2.44 |
% |
0.04 |
0.1 |
Shimadzu electronic balance post excision weight measurement |
|
|
0 |
|
|
|
71498 |
41 |
DA/Slc |
urine potassium excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine potassium amount |
male |
63 days
| 6 |
|
128.0 |
uEq/100g/6 hrs |
11.43 |
28.0 |
automated urine analysis |
|
|
0 |
|
Analytical intruments, PVA alpha II |
|
94833 |
1662 |
DA/Slc |
squamous cell carcinoma of the tongue tumor number |
controlled 4-nitroquinoline N-oxide content drinking water (0.001 %) (for 0.1 hours) |
Tanuma J, et al., Cancer Res 1998 Apr 15;58(8):1660-4 |
tongue integrity trait |
both |
42 days-222 days |
47 |
|
1.49 |
null |
0.1 |
0.66 |
necropsy |
0.0 |
|
0 |
|
until moribund or 180days of exp |
error type not specified |
70395 |
1398 |
DA/Slc |
squamous cell carcinoma of the tongue tumor number |
controlled 4-nitroquinoline N-oxide content drinking water (10 mg/l) (for 180 days) |
Hirano M, et al., Cancer Lett 2005 May 2;. |
tongue integrity trait |
both |
42 days-222 days |
20 |
|
2.35 |
null |
0.22 |
0.99 |
necropsy |
0.0 |
|
0 |
|
|
180 day maximum |
70317 |
1339 |
DA/Slc |
squamous cell carcinoma of the tongue maximum tumor diameter |
controlled 4-nitroquinoline N-oxide content drinking water (10 mg/l) (for 180 days) |
Hirano M, et al., Cancer Lett 2005 May 2;. |
tongue integrity trait |
both |
42 days-222 days |
20 |
|
10.35 |
mm |
0.95 |
4.26 |
necropsy |
0.0 |
|
0 |
|
|
180 day maximum |
70323 |
1339 |
DA/Slc |
plasma alkaline phosphatase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood alkaline phosphatase amount |
male |
70 days
| 6 |
|
248.0 |
IU/l |
4.49 |
11.0 |
automated plasma analysis |
|
|
0 |
|
PMID:15591307 |
|
76709 |
1498 |
DA/Slc |
plasma high density lipoprotein cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood HDL cholesterol amount |
male |
70 days
| 6 |
|
44.4 |
mg/dl |
1.55 |
3.8 |
automated plasma analysis |
|
|
0 |
|
PMID:15591307 |
|
76715 |
1498 |
DA/Slc |
plasma creatinine level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood creatinine amount |
male |
70 days
| 6 |
|
0.24 |
mg/dl |
0.01 |
0.02 |
automated plasma creatinine analysis |
|
|
0 |
|
Hitachi, model 7170 |
|
76720 |
1498 |
DA/Slc |
blood monocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
monocyte quantity |
male |
70 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
|
0 |
|
May-Giemsa staining |
|
76731 |
1498 |
DA/Slc |
single kidney wet weight to body weight ratio |
anti-glomerular basement membrane antibody (500 ul) |
Kose H, et al., Exp Anim. 2009 Apr;58(2):193-8. |
kidney mass |
female |
64 days
| 10 |
|
8.2 |
g/kg |
|
|
post excision weight measurement |
0.0 |
antibody injection |
8 |
days |
|
percentage of kidney weight/body weight |
67687 |
307 |
DA/Slc |
plasma urea nitrogen level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood urea nitrogen amount |
male |
70 days
| 6 |
|
6.25 |
mmol/l |
0.23 |
0.57 |
automated plasma analysis |
|
|
0 |
|
PMID:15591307 |
|
76719 |
1498 |
DA/Slc |
plasma phosphate level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood phosphate amount |
male |
70 days
| 6 |
|
7.8 |
mg/dl |
0.16 |
0.4 |
automated blood electrolyte analysis |
|
|
0 |
|
Hitachi, model 7170 |
|
76721 |
1498 |
DA/Slc |
blood segmented neutrophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
neutrophil quantity |
male |
70 days
| 6 |
|
12.0 |
% |
3.27 |
8.0 |
automated differential white blood cell count test |
|
|
0 |
|
May-Giemsa staining |
segmented neutrophil % |
76729 |
1498 |
DA/Slc |
non-specified leukocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
leukocyte quantity |
male |
70 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
|
0 |
|
May-Giemsa staining |
unidentified differential wbc |
76732 |
1498 |
DA/Slc |
systolic blood pressure |
specific pathogen-free condition |
NBRP Blood Pressure and Heart Rate data |
arterial blood pressure trait |
male |
56 days-70 days |
6 |
serial mean |
145.0 |
mmHg |
4.08 |
10.0 |
tail cuff photoplethysmography |
|
|
0 |
|
NP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japan |
|
74922 |
14 |
DA/Slc |
post-insult time to onset of moribundity |
controlled 4-nitroquinoline N-oxide content drinking water (10 mg/l) (for 180 days) |
Hirano M, et al., Cancer Lett 2005 May 2;. |
life span trait |
both |
42 days-222 days |
20 |
|
161.45 |
d |
2.85 |
12.73 |
ex vivo visual assessment |
0.0 |
|
0 |
|
|
180 day maximum |
70329 |
1339 |
DA/Slc |
non-tongue squamous cell carcinoma of the head and neck tumor number |
controlled 4-nitroquinoline N-oxide content drinking water (0.001 %) (for 0.1 hours) |
Tanuma J, et al., Cancer Res 1998 Apr 15;58(8):1660-4 |
head and neck integrity trait |
both |
42 days-222 days |
47 |
|
1.83 |
null |
0.18 |
1.26 |
necropsy |
0.0 |
|
0 |
|
until moribund or 180days of exp |
error not specified |
70399 |
1398 |
DA/Slc |
platelet count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
platelet quantity |
male |
70 days
| 6 |
|
1032.0 |
x 1000 /ul |
17.15 |
42.0 |
automated cell/particle size/count analysis method |
|
|
0 |
|
Sysmex, F-800 type |
|
76704 |
1498 |
DA/Slc |
plasma albumin to plasma total protein ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood albumin amount |
male |
70 days
| 6 |
|
1.86 |
null |
0.06 |
0.15 |
automated plasma protein analysis |
|
|
0 |
|
Hitachi, model 7170 |
plasma albumin to plasma total protein ratio |
76712 |
1498 |
DA/Slc |
plasma sodium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood sodium amount |
male |
70 days
| 6 |
|
146.8 |
mmol/l |
0.9 |
2.2 |
automated blood electrolyte analysis |
|
|
0 |
|
Analytical intruments, PVA alpha II |
|
76723 |
1498 |