Phenominer Database Results (43 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Average Type Value Units SEM SD Method Method Site Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Record ID Study ID
LEW diastolic blood pressure control condition Ueno T, et al., Physiol Genomics 2004 Mar 12;17(1):38-47. arterial blood pressure trait male 151 days-181 days 9 80.3 mmHg 2.9 8.7 vascular indwelling catheter method carotid artery and jugular vein 0 polyethylene catheter 11716 120
LEW heart left atrium fractional shortening controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart left atrium diameter male 77 days 14 (LADs - LADd)/ LADs x 100 34.1 % 1.62 6.08 transthoracic echocardiography 0.0 0 heart left atrium fractional shortening 68321 542
LEW ejection fraction controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. cardiac output trait male 77 days 14 84.4 % 1.03 3.85 transthoracic echocardiography 0.0 0 68289 542
LEW heart weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 heart mass male 98 days 6 2.43 g/kg 0.01 0.02 post excision weight measurement 0 0 12125 226
LEW bone mineral density control condition Koller DL, et al., Mamm Genome 2005 Aug;16(8):578-86. Epub 2005 Sep 14. lumbar vertebra mineral mass female 182 days 16 0.24 g/cm2 0.0 0.01 dual-energy x-ray absorptiometry lumbar vertebrae 3-5 0.0 0 L3-L5 76295 1578
LEW peak aortic velocity controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. aorta blood flow trait male 77 days 14 94.6 cm/s 3.1 11.6 pulsed wave doppler ultrasound 0.0 0 peak aortic velocity 68241 542
LEW heart left ventricle weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 heart left ventricle mass male 98 days 6 1.87 mg/g 0.01 0.02 post excision weight measurement 0 0 64890 226
LEW both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 6 7.91 g/kg 0.09 0.22 post excision weight measurement 0 0 64771 226
LEW mean arterial blood pressure controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 50 days) Chauvet C, et al., J Hypertens. 2008 May;26(5):893-901. arterial blood pressure trait male 66 days-78 days 6 serial mean 95.0 mmHg 3.0 7.35 intra-aortic abdominal radiotelemetry abdominal aorta 1036800 0 telemetry probe model PA-D70, Data Sciences, St. Paul, MN average of 24 hour averages over 12 days 12736 304
LEW heart rate controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart pumping trait male 77 days 14 388.6 beats/min 9.19 34.4 transthoracic echocardiography 0 0 65012 542
LEW heart left ventricle wet weight controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart left ventricle mass male 77 days 14 0.72 g 0.03 0.13 post excision weight measurement 0 0 65027 542
LEW heart left ventricle end-systolic diameter controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart left ventricle end-systolic diameter male 77 days 14 3.69 mm 0.16 0.6 transthoracic echocardiography 0.0 0 heart left ventricle anterior wall thickness 68273 542
LEW volumetric bone mineral density control condition Koller DL, et al., Mamm Genome 2005 Aug;16(8):578-86. Epub 2005 Sep 14. lumbar vertebra mineral mass female 182 days 16 746.0 mg/cm3 7.25 29.0 ex vivo peripheral quantitative computed tomography lumbar vertebrae 3-5 0.0 0 L3-L5 76300 1578
LEW volumetric bone mineral density control condition Koller DL, et al., Mamm Genome 2005 Aug;16(8):578-86. Epub 2005 Sep 14. femur mineral mass female 182 days 16 709.0 mg/cm3 6.25 25.0 ex vivo peripheral quantitative computed tomography distal epiphysis of femur 0.0 0 76302 1578
LEW body weight control condition Ueno T, et al., Physiol Genomics 2004 Mar 12;17(1):38-47. body mass female 150 days-180 days 10 212.7 g 3.8 12.02 body weighing method 0 0 13154 120
LEW heart right ventricle weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 heart right ventricle mass male 98 days 6 0.54 mg/g 0.01 0.01 post excision weight measurement 0 0 64891 226
LEW mean arterial blood pressure losartan (10 mg/kg) (for 0.2 hours) Ueno T, et al., J Mol Med 2003 Jan;81(1):51-60. Epub 2002 Nov 21. arterial blood pressure trait both 151 days-181 days 21 continuous mean 102.0 mmHg 2.0 9.17 vascular indwelling catheter method carotid artery, jugular vein 1800 0 12393 249
LEW plasma triglyceride level control condition Ueno T, et al., Physiol Genomics 2004 Mar 12;17(1):38-47. blood triglyceride amount male 150 days-180 days 10 0.81 mmol/l 0.08 0.25 plasma triglyceride analysis 0 13142 120
LEW mean arterial blood pressure control condition Ueno T, et al., J Mol Med 2003 Jan;81(1):51-60. Epub 2002 Nov 21. arterial blood pressure trait both 151 days-181 days 21 continuous mean 107.0 mmHg 2.0 9.17 vascular indwelling catheter method carotid artery, jugular vein 1800 0 64701 249
LEW heart left ventricle end-diastolic diameter controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart left ventricle end-diastolic diameter male 77 days 14 7.16 mm 0.25 0.93 transthoracic echocardiography 0.0 0 heart left ventricle anterior wall thickness 68265 542
LEW mean arterial blood pressure losartan (10 mg/kg) (for 0.2 hours) then pentolinium (5 mg/kg) (for 0.1 hours) then NG-nitroarginine methyl ester (30 mg/kg) (for 0.3 hours) Ueno T, et al., J Mol Med 2003 Jan;81(1):51-60. Epub 2002 Nov 21. arterial blood pressure trait both 151 days-181 days 21 continuous mean 123.0 mmHg 5.0 22.91 vascular indwelling catheter method carotid artery, jugular vein 1800 0 64706 249
LEW diastolic blood pressure control condition Ueno T, et al., Physiol Genomics 2004 Mar 12;17(1):38-47. arterial blood pressure trait female 151 days-181 days 12 89.0 mmHg 2.5 8.66 vascular indwelling catheter method carotid artery and jugular vein 0 polyethylene catheter 11718 120
LEW heart left ventricle weight to body weight ratio controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart left ventricle mass male 77 days 14 2.42 mg/g 0.14 0.54 post excision weight measurement 0.0 0 68257 542
LEW plasma triglyceride level control condition Ueno T, et al., Physiol Genomics 2004 Mar 12;17(1):38-47. blood triglyceride amount female 150 days-180 days 10 1.11 mmol/l 0.1 0.32 plasma triglyceride analysis 0 13144 120
LEW plasma total cholesterol level control condition Ueno T, et al., Physiol Genomics 2004 Mar 12;17(1):38-47. blood cholesterol amount male 150 days-180 days 10 81.47 mg/dl 5.02 15.87 plasma total cholesterol measurement test 0 13149 120
LEW plasma total cholesterol level control condition Ueno T, et al., Physiol Genomics 2004 Mar 12;17(1):38-47. blood cholesterol amount male 150 days-180 days 10 113.13 mg/dl 4.63 14.65 plasma total cholesterol measurement test 0 13150 120
LEW systolic blood pressure control condition Ueno T, et al., Physiol Genomics 2004 Mar 12;17(1):38-47. arterial blood pressure trait female 151 days-181 days 12 138.8 mmHg 2.8 9.7 vascular indwelling catheter method carotid artery and jugular vein 0 polyethylene catheter 11717 120
LEW mean arterial blood pressure controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 23 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. arterial blood pressure trait male 56 days-60 days 6 95.0 mmHg 1.22 3.0 radiotelemetry 86400 0 two 24 hours widely separated periods, data represent averages of all readings over the 24-h measurements 64994 542
LEW body weight controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. body mass male 77 days 14 299.2 g 6.76 25.3 body weighing method 0 0 65004 542
LEW bone mineral density control condition Koller DL, et al., Mamm Genome 2005 Aug;16(8):578-86. Epub 2005 Sep 14. femur mineral mass female 182 days 16 0.24 g/cm2 0.0 0.01 dual-energy x-ray absorptiometry femur 0.0 0 L3-L5 76296 1578
LEW volumetric bone mineral density control condition Koller DL, et al., Mamm Genome 2005 Aug;16(8):578-86. Epub 2005 Sep 14. femur mineral mass female 182 days 16 1341.0 mg/cm3 2.75 11.0 ex vivo peripheral quantitative computed tomography diaphysis of femur 0.0 0 76301 1578
LEW heart left ventricle fractional shortening controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart left ventricle end-diastolic diameter male 77 days 14 (LVDdLVDs)/LVDd x 100 48.6 % 1.21 4.54 transthoracic echocardiography 0.0 0 heart left ventricle anterior wall thickness 68281 542
LEW heart left ventricle posterior wall thickness controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart left ventricle posterior wall thickness male 77 days 14 0.15 mm 0.0 0.01 transthoracic echocardiography 0 0 65114 542
LEW mean arterial blood pressure losartan (10 mg/kg) (for 0.2 hours) then pentolinium (5 mg/kg) (for 0.1 hours) Ueno T, et al., J Mol Med 2003 Jan;81(1):51-60. Epub 2002 Nov 21. arterial blood pressure trait both 151 days-181 days 21 continuous mean 45.0 mmHg 2.0 9.17 vascular indwelling catheter method carotid artery, jugular vein 1800 0 64703 249
LEW mean arterial blood pressure controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 arterial blood pressure trait male 68 days-98 days 6 95.0 mmHg 3.0 7.35 radiotelemetry 30 0 11972 226
LEW systolic blood pressure control condition Ueno T, et al., Physiol Genomics 2004 Mar 12;17(1):38-47. arterial blood pressure trait male 151 days-181 days 9 124.3 mmHg 3.9 11.7 vascular indwelling catheter method carotid artery and jugular vein 0 polyethylene catheter 11715 120
LEW body weight controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 body mass male 98 days 6 372.0 g 9.0 22.05 body weighing method 0 0 12080 226
LEW body weight control condition Ueno T, et al., Physiol Genomics 2004 Mar 12;17(1):38-47. body mass male 150 days-180 days 10 300.2 g 8.0 25.3 body weighing method 0 13153 120
LEW heart left atrium end-systolic diameter controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart left atrium diameter male 77 days 14 4.39 mm 0.13 0.48 transthoracic echocardiography 0.0 0 heart left atrium end-systolic diameter 68298 542
LEW percentage of study population developing experimental autoimmune encephalomyelitis during a period of time central nervous system myelin (5 mg/ml) and Freund's complete adjuvant (50 %) Roth MP, et al., J Immunol 1999 Feb 15;162(4):1917-22. central nervous system integrity trait not specified 70 days-122 days 9 100.0 % in vivo visual assessment 0.0 0 69968 1278
LEW heart isovolumetric relaxation time controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart muscle relaxation trait male 77 days 14 16.3 ms 0.71 2.66 continuous wave doppler ultrasound 0.0 0 isovolumetric relaxation time 68297 542
LEW heart left atrium end-diastolic diameter controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart left atrium diameter male 77 days 14 2.89 mm 0.1 0.38 transthoracic echocardiography 0.0 0 heart left atrium end-diastolic diameter 68306 542
LEW heart left ventricle anterior wall thickness controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart left ventricle anterior wall thickness male 77 days 14 0.15 mm 0.0 0.01 transthoracic echocardiography 0.0 0 heart left ventricle anterior wall thickness 68249 542