Phenominer Database Results (56 results)

 
 
Table "column sort" updates the order of the bars in the chart.
Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Record ID Study ID
Crl:CD(SD) retinal outer layer thickness vehicle control condition (0 mg/kg) (for 13 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 67 days-74 days 5 138.5 um 3.4 7.6 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography outer retinal layer 105474 3016
Crl:CD(SD) retinal outer nuclear layer thickness AMG-8718 (100 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal outer nuclear layer morphology trait male 137 days-144 days 5 49.2 um 2.95 6.6 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 outer nuc layer 105456 3016
Crl:CD(SD) retinal outer nuclear layer thickness AMG-8718 (600 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal outer nuclear layer morphology trait male 81 days-88 days 5 48.9 um 3.13 7.0 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 outer nuc layer 105445 3016
Crl:CD(SD) full retina thickness AMG-8718 (100 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 137 days-144 days 5 184.4 um 8.09 18.1 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 full retina layer 105460 3016
Crl:CD(SD) retinal outer layer thickness vehicle control condition (0 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 111 days-118 days 5 132.2 um 3.71 8.3 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography outer retinal layer 105490 3016
Crl:CD(SD) retinal outer layer thickness AMG-8718 (10 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 136 days-143 days 5 128.2 um 3.8 8.5 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography outer retinal layer 105499 3016
Crl:CD(SD) retinal inner layer thickness vehicle control condition (0 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 136 days-143 days 5 123.8 um 4.83 10.8 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography inner retinal layer 105502 3016
Crl:CD(SD) full retina thickness AMG-8718 (100 mg/kg) (for 5 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 59 days-66 days 5 122.2 um 4.07 9.1 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 full retina layer 105440 3016
Crl:CD(SD) retinal inner layer thickness AMG-8718 (10 mg/kg) (for 13 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 67 days-74 days 5 127.2 um 3.85 8.6 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography inner retinal layer 105479 3016
Crl:CD(SD) retinal inner layer thickness AMG-8718 (100 mg/kg) (for 13 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 67 days-74 days 5 128.6 um 4.11 9.2 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography inner retinal layer 105480 3016
Crl:CD(SD) retinal outer layer thickness AMG-8718 (600 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 136 days-143 days 5 112.7 um 2.91 6.5 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography outer retinal layer 105501 3016
Crl:CD(SD) retinal inner layer thickness AMG-8718 (600 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 111 days-118 days 5 120.9 um 5.19 11.6 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography inner retinal layer 105497 3016
Crl:CD(SD) retinal outer nuclear layer thickness AMG-8718 (10 mg/kg) (for 5 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal outer nuclear layer morphology trait male 59 days-66 days 5 40.8 um 1.25 2.8 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 outer nuc layer 105435 3016
Crl:CD(SD) retinal inner layer thickness vehicle control condition (0 mg/kg) (for 26 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 80 days-87 days 10 126.0 um 4.02 9.0 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography inner retinal layer 105486 3016
Crl:CD(SD) retinal outer layer thickness AMG-8718 (100 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 136 days-143 days 5 124.3 um 3.44 7.7 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography outer retinal layer 105500 3016
Crl:CD(SD) retinal outer layer thickness AMG-8718 (100 mg/kg) (for 13 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 67 days-74 days 5 138.9 um 3.49 7.8 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography outer retinal layer 105476 3016
Crl:CD(SD) retinal outer nuclear layer thickness vehicle control condition (0 mg/kg) (for 5 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal outer nuclear layer morphology trait male 59 days-66 days 5 41.0 um 1.12 2.5 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 outer nuc layer 105434 3016
Crl:CD(SD) full retina thickness AMG-8718 (100 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 81 days-88 days 5 185.4 um 5.41 12.1 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 full retina layer 105448 3016
Crl:CD(SD) full retina thickness AMG-8718 (600 mg/kg) (for 5 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 59 days-66 days 5 137.1 um 18.02 40.3 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 full retina layer 105441 3016
Crl:CD(SD) retinal inner layer thickness AMG-8718 (10 mg/kg) (for 26 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 80 days-87 days 10 125.1 um 3.98 8.9 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography inner retinal layer 105487 3016
Crl:CD(SD) retinal inner layer thickness AMG-8718 (600 mg/kg) (for 13 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 67 days-74 days 5 124.0 um 4.2 9.4 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography inner retinal layer 105481 3016
Crl:CD(SD) retinal outer nuclear layer thickness AMG-8718 (100 mg/kg) (for 5 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal outer nuclear layer morphology trait male 59 days-66 days 5 38.5 um 1.07 2.4 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 outer nuc layer 105436 3016
Crl:CD(SD) full retina thickness vehicle control condition (0 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 81 days-88 days 5 177.2 um 6.22 13.9 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 full retina layer 105446 3016
Crl:CD(SD) retinal outer layer thickness AMG-8718 (10 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 111 days-118 days 5 134.2 um 4.79 10.7 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography outer retinal layer 105491 3016
Crl:CD(SD) retinal inner layer thickness AMG-8718 (10 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 136 days-143 days 5 125.7 um 3.89 8.7 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography inner retinal layer 105503 3016
Crl:CD(SD) full retina thickness AMG-8718 (10 mg/kg) (for 5 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 59 days-66 days 5 128.0 um 4.74 10.6 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 full retina layer 105439 3016
Crl:CD(SD) retinal outer nuclear layer thickness vehicle control condition (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal outer nuclear layer morphology trait male 137 days-144 days 5 50.6 um 1.61 3.6 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 outer nuc layer 105454 3016
Crl:CD(SD) retinal inner layer thickness vehicle control condition (0 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 111 days-118 days 5 121.9 um 4.38 9.8 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography inner retinal layer 105494 3016
Crl:CD(SD) retinal inner layer thickness AMG-8718 (100 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 136 days-143 days 5 122.6 um 4.74 10.6 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography inner retinal layer 105504 3016
Crl:CD(SD) full retina thickness AMG-8718 (600 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 81 days-88 days 5 175.7 um 16.14 36.1 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 full retina layer 105449 3016
Crl:CD(SD) retinal outer nuclear layer thickness AMG-8718 (100 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal outer nuclear layer morphology trait male 81 days-88 days 5 55.6 um 1.25 2.8 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 outer nuc layer 105444 3016
Crl:CD(SD) retinal inner layer thickness AMG-8718 (600 mg/kg) (for 26 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 80 days-87 days 10 122.4 um 4.65 10.4 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography inner retinal layer 105489 3016
Crl:CD(SD) retinal outer layer thickness AMG-8718 (100 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 111 days-118 days 5 128.1 um 3.49 7.8 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography outer retinal layer 105492 3016
Crl:CD(SD) full retina thickness AMG-8718 (10 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 137 days-144 days 5 207.4 um 18.87 42.2 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 full retina layer 105459 3016
Crl:CD(SD) retinal inner layer thickness AMG-8718 (100 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 111 days-118 days 5 120.7 um 4.2 9.4 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography inner retinal layer 105496 3016
Crl:CD(SD) retinal outer layer thickness vehicle control condition (0 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 136 days-143 days 5 129.8 um 4.02 9.0 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography outer retinal layer 105498 3016
Crl:CD(SD) retinal outer nuclear layer thickness AMG-8718 (10 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal outer nuclear layer morphology trait male 137 days-144 days 5 51.1 um 1.65 3.7 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 outer nuc layer 105455 3016
Crl:CD(SD) full retina thickness vehicle control condition (0 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 137 days-144 days 5 191.6 um 7.56 16.9 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 full retina layer 105458 3016
Crl:CD(SD) full retina thickness AMG-8718 (600 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 137 days-144 days 5 167.0 um 6.98 15.6 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 full retina layer 105461 3016
Crl:CD(SD) retinal inner layer thickness AMG-8718 (600 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 136 days-143 days 5 120.4 um 4.25 9.5 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography inner retinal layer 105505 3016
Crl:CD(SD) retinal outer layer thickness vehicle control condition (0 mg/kg) (for 26 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 80 days-87 days 10 136.0 um 3.49 7.8 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography outer retinal layer 105482 3016
Crl:CD(SD) retinal outer layer thickness AMG-8718 (10 mg/kg) (for 13 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 67 days-74 days 5 138.8 um 3.67 8.2 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography outer retinal layer 105475 3016
Crl:CD(SD) retinal outer layer thickness AMG-8718 (600 mg/kg) (for 13 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 67 days-74 days 5 132.1 um 3.18 7.1 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography outer retinal layer 105477 3016
Crl:CD(SD) retinal outer layer thickness AMG-8718 (600 mg/kg) (for 26 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 80 days-87 days 10 133.4 um 3.04 6.8 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography outer retinal layer 105485 3016
Crl:CD(SD) retinal outer layer thickness AMG-8718 (600 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 111 days-118 days 5 118.6 um 3.35 7.5 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography outer retinal layer 105493 3016
Crl:CD(SD) retinal inner layer thickness AMG-8718 (10 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 111 days-118 days 5 126.1 um 4.11 9.2 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography inner retinal layer 105495 3016
Crl:CD(SD) retinal outer layer thickness AMG-8718 (10 mg/kg) (for 26 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 80 days-87 days 10 137.0 um 3.44 7.7 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography outer retinal layer 105483 3016
Crl:CD(SD) retinal outer nuclear layer thickness AMG-8718 (10 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal outer nuclear layer morphology trait male 81 days-88 days 5 52.5 um 2.33 5.2 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 outer nuc layer 105443 3016
Crl:CD(SD) full retina thickness AMG-8718 (10 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 81 days-88 days 5 175.9 um 9.17 20.5 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 full retina layer 105447 3016
Crl:CD(SD) retinal outer nuclear layer thickness AMG-8718 (600 mg/kg) (for 5 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal outer nuclear layer morphology trait male 59 days-66 days 5 38.6 um 1.07 2.4 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 outer nuc layer 105437 3016
Crl:CD(SD) full retina thickness vehicle control condition (0 mg/kg) (for 5 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 59 days-66 days 5 129.7 um 3.71 8.3 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 full retina layer 105438 3016
Crl:CD(SD) retinal outer nuclear layer thickness AMG-8718 (600 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal outer nuclear layer morphology trait male 137 days-144 days 5 40.9 um 2.15 4.8 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 outer nuc layer 105457 3016
Crl:CD(SD) retinal inner layer thickness vehicle control condition (0 mg/kg) (for 13 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 67 days-74 days 5 128.7 um 4.92 11.0 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography inner retinal layer 105478 3016
Crl:CD(SD) retinal inner layer thickness AMG-8718 (100 mg/kg) (for 26 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 80 days-87 days 10 124.7 um 3.89 8.7 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography inner retinal layer 105488 3016
Crl:CD(SD) retinal outer layer thickness AMG-8718 (100 mg/kg) (for 26 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal layer morphology trait male 80 days-87 days 10 138.5 um 4.25 9.5 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 optical coherence tomography outer retinal layer 105484 3016
Crl:CD(SD) retinal outer nuclear layer thickness vehicle control condition (0 mg/kg) (for 25 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. retinal outer nuclear layer morphology trait male 81 days-88 days 5 53.4 um 2.33 5.2 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 outer nuc layer 105442 3016