Crl:CD(SD) |
liver oxidized glutathione level to liver weight ratio |
standard diet and restricted feeding (4 h) (for 114 days) then fasting (for 20 hours) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver glutathione amount |
male |
170 days
| 19 |
0.17 |
umol/g |
0.0 |
0.02 |
reduced glutathione/oxidized glutathione enzyme recycling assay |
0.0 |
0 |
enzyme recycling method |
|
85409 |
1604 |
Crl:CD(SD) |
liver reduced glutathione level to liver weight ratio |
standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (300 mg/kg) (for 99 days) then fasting (for 20 hours) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver glutathione amount |
male |
170 days
| 8 |
6.24 |
umol/g |
0.31 |
0.87 |
reduced glutathione/oxidized glutathione enzyme recycling assay |
0.0 |
0 |
enzyme recycling method |
|
85570 |
1604 |
Crl:CD(SD) |
liver oxidized glutathione level to liver weight ratio |
standard diet then acetaminophen (300 mg/kg) (for 99 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver glutathione amount |
male |
170 days
| 8 |
0.24 |
umol/g |
0.01 |
0.02 |
reduced glutathione/oxidized glutathione enzyme recycling assay |
0.0 |
0 |
enzyme recycling method |
reduced liver glutathione level to liver weight ratio |
85573 |
1604 |
Crl:CD(SD) |
liver oxidized glutathione level to liver weight ratio |
standard diet |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver glutathione amount |
male |
170 days
| 19 |
0.21 |
umol/g |
0.01 |
0.03 |
reduced glutathione/oxidized glutathione enzyme recycling assay |
0.0 |
0 |
enzyme recycling method |
oxidized liver glutathione level to liver weight ratio |
85408 |
1604 |
Crl:CD(SD) |
liver oxidized glutathione level to liver weight ratio |
standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (300 mg/kg) (for 99 days) then fasting (for 20 hours) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver glutathione amount |
male |
170 days
| 8 |
0.16 |
umol/g |
0.01 |
0.03 |
reduced glutathione/oxidized glutathione enzyme recycling assay |
0.0 |
0 |
enzyme recycling method |
|
85576 |
1604 |
Crl:CD(SD) |
liver reduced glutathione level to liver weight ratio |
standard diet |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver glutathione amount |
male |
170 days
| 19 |
7.12 |
umol/g |
0.07 |
0.31 |
reduced glutathione/oxidized glutathione enzyme recycling assay |
0.0 |
0 |
enzyme recycling method |
reduced liver glutathione level to liver weight ratio |
85406 |
1604 |
Crl:CD(SD) |
liver oxidized glutathione level to liver weight ratio |
standard diet then acetaminophen (500 mg/kg) (for 99 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver glutathione amount |
male |
170 days
| 8 |
0.19 |
umol/g |
0.01 |
0.03 |
reduced glutathione/oxidized glutathione enzyme recycling assay |
0.0 |
0 |
enzyme recycling method |
reduced liver glutathione level to liver weight ratio |
85574 |
1604 |
Crl:CD(SD) |
liver oxidized glutathione level to liver weight ratio |
standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (500 mg/kg) (for 99 days) then fasting (for 20 hours) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver glutathione amount |
male |
170 days
| 8 |
0.14 |
umol/g |
0.0 |
0.01 |
reduced glutathione/oxidized glutathione enzyme recycling assay |
0.0 |
0 |
enzyme recycling method |
|
85577 |
1604 |
Crl:CD(SD) |
liver reduced glutathione level to liver weight ratio |
standard diet then acetaminophen (300 mg/kg) (for 99 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver glutathione amount |
male |
170 days
| 8 |
9.16 |
umol/g |
0.18 |
0.5 |
reduced glutathione/oxidized glutathione enzyme recycling assay |
0.0 |
0 |
enzyme recycling method |
reduced liver glutathione level to liver weight ratio |
85567 |
1604 |
Crl:CD(SD) |
liver reduced glutathione level to liver weight ratio |
standard diet and restricted feeding (4 h) (for 114 days) then fasting (for 20 hours) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver glutathione amount |
male |
170 days
| 19 |
6.1 |
umol/g |
0.15 |
0.67 |
reduced glutathione/oxidized glutathione enzyme recycling assay |
0.0 |
0 |
enzyme recycling method |
|
85407 |
1604 |
Crl:CD(SD) |
liver reduced glutathione level to liver weight ratio |
standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (500 mg/kg) (for 99 days) then fasting (for 20 hours) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver glutathione amount |
male |
170 days
| 8 |
5.19 |
umol/g |
0.24 |
0.69 |
reduced glutathione/oxidized glutathione enzyme recycling assay |
0.0 |
0 |
enzyme recycling method |
|
85571 |
1604 |
Crl:CD(SD) |
liver reduced glutathione level to liver weight ratio |
standard diet then acetaminophen (500 mg/kg) (for 99 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver glutathione amount |
male |
170 days
| 8 |
9.07 |
umol/g |
0.25 |
0.72 |
reduced glutathione/oxidized glutathione enzyme recycling assay |
0.0 |
0 |
enzyme recycling method |
reduced liver glutathione level to liver weight ratio |
85568 |
1604 |